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https://www.readbyqxmd.com/read/28330669/czt-spect-reaching-its-potential
#1
EDITORIAL
Lawrence M Phillips
No abstract text is available yet for this article.
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28330657/diagnostic-accuracy-of-myocardial-perfusion-imaging-with-czt-technology-systemic-review-and-meta-analysis-of-comparison-with%C3%A2-invasive-coronary-angiography
#2
Francesco Nudi, Ami E Iskandrian, Orazio Schillaci, Mariangela Peruzzi, Giacomo Frati, Giuseppe Biondi-Zoccai
OBJECTIVES: This study sought to summarize the evidence on stress myocardial perfusion imaging (MPI) using cadmium-zinc-telluride (CZT) technology for the diagnosis of obstructive coronary artery disease (CAD). The CZT cameras are newly introduced, and comparative data with the conventional Anger technology (Anger-MPI) are lacking. BACKGROUND: The diagnostic accuracy of Anger-MPI for detection of angiographically significant CAD is well established; however, less evidence is available on the diagnostic accuracy of CZT-MPI...
March 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28276752/new-solid-state-cadmium-zinc-telluride-technology-for-cardiac-single-photon-emission-computed-tomographic-myocardial-perfusion-imaging
#3
REVIEW
Ali B Alenazy, R Glenn Wells, Terrence D Ruddy
Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is well established as diagnostic test for patients with suspected or known coronary artery disease. New camera systems have been developed with cadmium-zinc-telluride (CZT) detectors, novel collimator designs and reconstruction software. Areas covered: We review the current state of cardiac SPECT, advances in conventional camera technology and the development and clinical validation of solid-state CZT cameras. Expert commentary: The development of CZT systems is timely and addresses current issues for clinical SPECT imaging...
March 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/28275896/first-assessment-of-simultaneous-dual-isotope-123-i-99m-tc-cardiac-spect-on-two-different-czt-cameras-a-phantom-study
#4
Tanguy Blaire, Alban Bailliez, Fayçal Ben Bouallegue, Dimitri Bellevre, Denis Agostini, Alain Manrique
BACKGROUND: We studied the impact of simultaneous dual-isotope acquisition on (123)I/(99m)Tc mismatch assessment using two CZT cameras (DNM 530c, GE Healthcare and DSPECT, Biosensors International). METHODS: We used an anthropomorphic torso phantom (respectively filled with a solution of (123)I alone, (99m)Tc alone, and a mixture of (123)I and (99m)Tc) and its cardiac insert with two defects mimicking two matched and mismatched defects. Mismatch extent and reconstructed image contrast were evaluated...
March 8, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28198517/a-monte-carlo-study-for-optimizing-the-detector-of-spect-imaging-using-a-xcat-human-phantom
#5
Mohammad Khoshakhlagh, Jalil Pirayesh Islamian, Seyyed Mohammad Abedi, Babak Mahmoudian, Masoud Shayesteh Azar
BACKGROUND: Acquiring a high quality image has assigned an important concern for obtaining accurate diagnosis in nuclear medicine. Detector is a critical component of Single Photon Emission Computed Tomography (SPECT) imaging system for giving accurate information from exact pattern of radionuclide distribution in the target organ. The images are strongly affected by the attenuation, scattering, and response of the detector. The conventional detector is mainly made from sodium iodide activated by thallium [NaI(Tl)] in nuclear medicine imaging...
2017: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/28194726/validation-of-cadmium-zinc-telluride-camera-for-measurement-of-left-ventricular-systolic-performance
#6
Elisabeth Coupez, Charles Merlin, Viateur Tuyisenge, Laurent Sarry, Bruno Pereira, Jean René Lusson, Louis Boyer, Lucie Cassagnes
BACKGROUND: There are paucity of data comparing measurements of left ventricular systolic performance using cadmium-zinc-telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging. METHODS: 60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI...
February 13, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28176253/tl-201-dosing-for-czt-spect-more-new-information
#7
EDITORIAL
M J Henzlova, W L Duvall
No abstract text is available yet for this article.
February 7, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28160264/impact-of-data-driven-cardiac-respiratory-motion-correction-on-the-extent-and-severity-of-myocardial-perfusion-defects-with-free-breathing-czt-spect
#8
Doumit Daou, Rémy Sabbah, Carlos Coaguila, Hatem Boulahdour
BACKGROUND: We previously reported the clinical feasibility and positive impact on image characteristics of a data-driven cardiac respiratory motion (RM) correction method (REGAT) applicable to CZT SPECT myocardial perfusion imaging (MPI). Here, we evaluate its impact on the extent and severity of myocardial perfusion defects (MPD). METHODS: We included 25 patients having a 1-day (99m)Tc-Tetrofosmin stress/rest MPI acquired with multi-pinhole CZT SPECT. Acquisitions were processed with REGAT to generate mean RM gated SPECT...
February 3, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28008559/optimal-thallium-201-dose-in-cadmium-zinc-telluride-spect-myocardial-perfusion-imaging
#9
Masaru Ishihara, Yasuyo Taniguchi, Masahisa Onoguchi, Takayuki Shibutani
BACKGROUND: We aimed to determine the optimal thallium 201 chloride (thallium-201) dose using a novel ultrafast cardiac gamma camera with cadmium-zinc-telluride (CZT) solid-state semiconductor detectors (D-SPECT). METHODS AND RESULTS: The optimal thallium-201 dose for obtaining left ventricular (LV) myocardial counts was determined from a phantom study. Consecutive 292 patients underwent stress myocardial perfusion imaging with a thallium-201 injection. Stress test comprised exercise or pharmacological (adenosine) provocation...
December 22, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27845567/spect-ct-an-update-on-technological-developments-and-clinical-applications
#10
Michael Ljungberg, P Hendrik Pretorius
Functional nuclear medicine imaging with single-photon emission CT (SPECT) in combination with anatomical CT has been commercially available since the beginning of this century. The combination of the two modalities has improved both the sensitivity and specificity of many clinical applications and CT in conjunction with SPECT that allows for spatial overlay of the SPECT data on good anatomy images. Introduction of diagnostic CT units as part of the SPECT/CT system has also potentially allowed for a more cost-efficient use of the equipment...
January 16, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/27677613/routine-evaluation-of-left-ventricular-function-using-czt-spect-with-low-injected-activities-and-limited-recording-times
#11
Marine Claudin, Laetitia Imbert, Wassila Djaballah, Nicolas Veran, Sylvain Poussier, Véronique Roch, Mathieu Perrin, Antoine Verger, Henri Boutley, Gilles Karcher, Pierre-Yves Marie
PURPOSE: Gamma-cameras, with Cadmium-Zinc-Telluride (CZT) detectors, allow to perform myocardial perfusion imaging (MPI) with limited injected activities and recorded times. This study aimed at determining whether the routine assessment of left ventricular (LV) function with such limited counts protocols compares well with reference values from cardiac MRI. METHODS: The study included patients who have undergone cardiac MRI and an MPI routinely planned on a CZT camera with a low-dose protocol (120 MBq of Sestamibi for stress and 360 MBq at rest for 75 kg body weight), while targeting the recording of only 500 myocardial kcounts in order to limit the recording times (<10 minutes for stress, <4 minutes for rest)...
September 27, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27542010/performance-of-cardiac-cadmium-zinc-telluride-gamma-camera-imaging-in-coronary-artery-disease-a-review-from-the-cardiovascular-committee-of-the-european-association-of-nuclear-medicine-eanm
#12
REVIEW
Denis Agostini, Pierre-Yves Marie, Simona Ben-Haim, François Rouzet, Bernard Songy, Alessandro Giordano, Alessia Gimelli, Fabien Hyafil, Roberto Sciagrà, Jan Bucerius, Hein J Verberne, Riemer H J A Slart, Oliver Lindner
The trade-off between resolution and count sensitivity dominates the performance of standard gamma cameras and dictates the need for relatively high doses of radioactivity of the used radiopharmaceuticals in order to limit image acquisition duration. The introduction of cadmium-zinc-telluride (CZT)-based cameras may overcome some of the limitations against conventional gamma cameras. CZT cameras used for the evaluation of myocardial perfusion have been shown to have a higher count sensitivity compared to conventional single photon emission computed tomography (SPECT) techniques...
December 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27538570/applicability-of-data-driven-respiratory-motion-correction-to-czt-spect-myocardial-perfusion-imaging-in-the-clinical-setting-the-birth-of-an-old-wish
#13
Doumit Daou, Remy Sabbah, Carlos Coaguila, Hatem Boulahdour
No abstract text is available yet for this article.
August 18, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27510176/comparison-of-the-prognostic-value-of-myocardial-perfusion-imaging-using-a-czt-spect-camera-with-a-conventional-anger-camera
#14
Ronaldo Lima, Thais Peclat, Thalita Soares, Caio Ferreira, Ana Carolina Souza, Gabriel Camargo
BACKGROUND: Recent studies have shown that myocardial perfusion imaging (MPI) in cadmium-zinc-telluride (CZT) cameras allow faster exams with less radiation dose but there are little data comparing its prognosis information with that of dedicated cardiac Na-I SPECT cameras OBJECTIVE: The objective of this study is to compare the prognostic value of MPI using an ultrafast protocol with low radiation dose in a CZT-SPECT and a traditional one. METHODS: Group 1 was submitted to a two-day MIBI protocol in a conventional camera, and group 2 was submitted to a 1-day MIBI protocol in CZT camera...
August 10, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27469371/simultaneous-dual-isotope-solid-state-detector-spect-for-improved-tracking-of-white-blood-cells-in-suspected-endocarditis
#15
Federico Caobelli, Tim Wollenweber, Udo Bavendiek, Christian Kühn, Christian Schütze, Lilli Geworski, James T Thackeray, Johann Bauersachs, Axel Haverich, Frank M Bengel
AIMS: High-energy resolution and sensitivity of novel cadmium-zinc-telluride (CZT) detector equipped SPECT systems facilitate simultaneous imaging of multiple isotopes and may enhance the detection of molecular/cellular signals. This may refine the detection of endocarditis. This study was designed to determine the feasibility and diagnostic accuracy of simultaneous imaging of inflammation with (111)In-labeled white blood cells (WBCs) and myocardial perfusion with (99m)Tc-sestamibi, for localization of WBCs relative to the valve plane in suspected endocarditis...
July 28, 2016: European Heart Journal
https://www.readbyqxmd.com/read/27417733/motion-detection-and-amelioration-in-a-dedicated-cardiac-solid-state-czt-spect-device
#16
John A Kennedy, H William Strauss
A solid-state cadmium zinc tellurium (CZT) dedicated multipinhole cardiac camera which acquires all views simultaneously has been introduced for myocardial SPECT acquisition. We report a method to detect and ameliorate patient motion artifacts in myocardial perfusion imaging (MPI) studies recorded with this device. To detect motion, a myocardial phantom study was recorded, and at mid-scan, the phantom was moved stepwise along each of 6 orthogonal directions, causing MPI artifacts. Using QPS software (Cedars-Sinai) and an in-house normal database, displacements giving artifactual perfusion defects (total perfusion deficit score, TPD, >5 %) were all 1...
July 14, 2016: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/27406376/value-of-automatic-patient-motion-detection-and-correction-in-myocardial-perfusion-imaging-using-a-czt-based-spect-camera
#17
Joris D van Dijk, Jorn A van Dalen, Mohamed Mouden, Jan Paul Ottervanger, Siert Knollema, Cornelis H Slump, Pieter L Jager
BACKGROUND: Correction of motion has become feasible on cadmium-zinc-telluride (CZT)-based SPECT cameras during myocardial perfusion imaging (MPI). Our aim was to quantify the motion and to determine the value of automatic correction using commercially available software. METHODS AND RESULTS: We retrospectively included 83 consecutive patients who underwent stress-rest MPI CZT-SPECT and invasive fractional flow reserve (FFR) measurement. Eight-minute stress acquisitions were reformatted into 1...
July 12, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/27363834/absolute-myocardial-blood-flow-and-flow-reserve-assessed-by-gated-spect-with-cadmium-zinc-telluride-detectors-using-99mtc-tetrofosmin-head-to-head-comparison-with-13n-ammonia-pet
#18
Rene Nkoulou, Tobias A Fuchs, Aju P Pazhenkottil, Silke M Kuest, Jelena R Ghadri, Julia Stehli, Michael Fiechter, Bernhard A Herzog, Oliver Gaemperli, Ronny R Buechel, Philipp A Kaufmann
Recent advances in SPECT technology including cadmium-zinc-telluride (CZT) semiconductor detector material may pave the way for absolute myocardial blood flow (MBF) measurements by SPECT. The aim of the present study was to compare K1 uptake rate constants as surrogates of absolute MBF and myocardial flow reserve index (MFRi) in humans as assessed with a CZT SPECT camera versus PET. METHODS: Absolute MBF was assessed in 28 consecutive patients undergoing adenosine stress-rest myocardial perfusion imaging (MPI) by (99m)Tc-tetrofosmin CZT SPECT and (13)N-ammonia PET, and MFR was calculated as a ratio of hyperemic over resting MBF...
December 2016: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/27250348/feasibility-of-ultra-low-dose-thallium-stress-redistribution-protocol-including-prone-imaging-in-obese-patients-using-czt-camera
#19
Vladimír Kincl, Milan Kamínek, Jiří Vašina, Roman Panovský, Martin Havel
High efficiency cadmium-zinc-telluride (CZT) cameras provide an opportunity to lower the injected activities of radiopharmaceuticals for single photon emission tomography (SPECT) myocardial perfusion imaging (MPI). The limits for reducing activities of thallium have not been determined, particularly in obese patients. After an injection of 0.7 megabecquerel (MBq) of thallium/kg, we collected an average 1.5 million counts for the 10-min acquisition in a pilot cohort of ten patients. After extrapolation, we reduced the administered activity to 0...
September 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27240368/evaluation-of-a-wobbling-method-applied-to-correcting-defective-pixels-of-czt-detectors-in-spect-imaging
#20
Zhaoheng Xie, Suying Li, Kun Yang, Baixuan Xu, Qiushi Ren
In this paper, we propose a wobbling method to correct bad pixels in cadmium zinc telluride (CZT) detectors, using information of related images. We build up an automated device that realizes the wobbling correction for small animal Single Photon Emission Computed Tomography (SPECT) imaging. The wobbling correction method is applied to various constellations of defective pixels. The corrected images are compared with the results of conventional interpolation method, and the correction effectiveness is evaluated quantitatively using the factor of peak signal-to-noise ratio (PSNR) and structural similarity (SSIM)...
2016: Sensors
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