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Contralateral prophylactic mastectomy

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https://www.readbyqxmd.com/read/27815748/a-model-for-individualized-risk-prediction-of-contralateral-breast-cancer
#1
Marzana Chowdhury, David Euhus, Tracy Onega, Swati Biswas, Pankaj K Choudhary
PURPOSE: Patients diagnosed with invasive breast cancer (BC) or ductal carcinoma in situ are increasingly choosing to undergo contralateral prophylactic mastectomy (CPM) to reduce their risk of contralateral BC (CBC). This is a particularly disturbing trend as a large proportion of these CPMs are believed to be medically unnecessary. Many BC patients tend to substantially overestimate their CBC risk. Thus, there is a pressing need to educate patients effectively on their CBC risk. We develop a CBC risk prediction model to aid physicians in this task...
November 4, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27787313/new-advisory-on-contralateral-prophylactic-mastectomy
#2
Joan Zolot
Breast surgeons recommend against the procedure unless cancer risk is increased.
November 2016: American Journal of Nursing
https://www.readbyqxmd.com/read/27783164/guidelines-for-guidelines-an-assessment-of-the-american-society-of-breast-surgeons-contralateral-prophylactic-mastectomy-consensus-statement
#3
EDITORIAL
Todd M Tuttle, Andrea V Barrio, V Suzanne Klimberg, Armando E Giuliano, Mariana Chavez-MacGregor, Heather A Thompson Buum, Kelly M McMasters
No abstract text is available yet for this article.
October 25, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27779988/is-sentinel-lymph-node-dissection-necessary-in-all-patients-with-ductal-carcinoma-in-situ-undergoing-total-mastectomy
#4
Valentina Bonev, Carlos Chavez De Paz Villanueva, Naveenraj Solomon, Maheswari Senthil, Mark E Reeves, Carlos Garberoglio, Sharon S Lum
When ductal carcinoma in situ (DCIS) is found on core needle biopsy, rates of upgrade to invasive cancer of 25 per cent and nodal positivity of 10 per cent have been reported. Sentinel lymph node dissection (SLND) is recommended when mastectomy is performed for DCIS. We investigated the role of SLND in DCIS patients undergoing partial and total mastectomy (TM). During the study period 2004 to 2013, 170 patients with DCIS were identified with a median age of 60 years (range 26-84 years). Of these, 58.2 per cent had partial mastectomy (PM) alone, 10...
October 2016: American Surgeon
https://www.readbyqxmd.com/read/27674591/contralateral-breast-cancer-risk-and-the-selection-of-contralateral-prophylactic-mastectomy-among-women-with-unilateral-breast-cancer
#5
J V Hegde, J Wang, A Kusske, S A McCloskey
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27650678/outcomes-of-contralateral-prophylactic-mastectomy-in-relation-to-familial-history-a-decision-analysis-brcr-d-16-00033
#6
Kalatu R Davies, Abenaa M Brewster, Isabelle Bedrosian, Patricia A Parker, Melissa A Crosby, Susan K Peterson, Yu Shen, Robert J Volk, Scott B Cantor
BACKGROUND: Family history of breast cancer is associated with an increased risk of contralateral breast cancer (CBC) even in the absence of mutations in the breast cancer susceptibility genes BRCA1/2. We compared quality-adjusted survival after contralateral prophylactic mastectomy (CPM) with surveillance only (no CPM) among women with breast cancer incorporating the degree of family history. METHODS: We created a microsimulation model for women with first-degree, second-degree, and no family history treated for a stage I, II, or III estrogen receptor (ER)-positive or ER-negative breast cancer at the ages of 40, 50, 60, and 70...
2016: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/27624164/subsequent-risk-of-ipsilateral-and-contralateral-invasive-breast-cancer-after-treatment-for-ductal-carcinoma-in-situ-incidence-and-the-effect-of-radiotherapy-in-a-population-based-cohort-of-10-090-women
#7
Lotte E Elshof, Michael Schaapveld, Marjanka K Schmidt, Emiel J Rutgers, Flora E van Leeuwen, Jelle Wesseling
PURPOSE: To assess the effect of different treatment strategies on the risk of subsequent invasive breast cancer (IBC) in women diagnosed with ductal carcinoma in situ (DCIS). METHODS: Up to 15-year cumulative incidences of ipsilateral IBC (iIBC) and contralateral IBC (cIBC) were assessed among a population-based cohort of 10,090 women treated for DCIS in the Netherlands between 1989 and 2004. Multivariable Cox regression analyses were used to evaluate associations of treatment with iIBC risk...
October 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27576011/why-are-there-so-many-mastectomies-in-the-united-states
#8
Anita Mamtani, Monica Morrow
Breast-conserving therapy (BCT) and mastectomy result in equivalent longterm survival. Locoregional recurrence rates after BCT have decreased over time and are now similar to those after mastectomy. Contralateral breast cancer rates are declining as well owing to the widespread use of adjuvant systemic therapy. Despite these improved outcomes, increasing rates of bilateral mastectomy for unilateral cancer have been observed in the United States. Medical indications for mastectomy are well defined and present in a minority of patients, and women at increased risk for contralateral cancer are a small proportion of the breast cancer population...
August 26, 2016: Annual Review of Medicine
https://www.readbyqxmd.com/read/27564723/differences-between-breast-conservation-eligible-patients-and-unilateral-mastectomy-patients-in-choosing-contralateral-prophylactic-mastectomies
#9
Michael S Sabel, Casey T Kraft, Kent A Griffith, Jessica M Bensenhaver, Lisa A Newman, Sarah T Hawley, Adeyiza O Momoh
There has been an increasing use of bilateral mastectomy (BM) for breast cancer. We sought to examine our trends among breast conservation (BCT) candidates and women recommended for unilateral mastectomy (UM). Our prospective breast cancer database was queried for women with a first-time, unilateral breast cancer. Patient and histologic factors and surgical treatment, including reconstruction, were evaluated. A detailed chart review was performed among patients from two representative time periods as to the reasons the patient underwent mastectomy...
November 2016: Breast Journal
https://www.readbyqxmd.com/read/27562384/contralateral-prophylactic-mastectomy-and-its-impact-on-quality-of-life
#10
COMMENT
Tina J Hieken, Judy C Boughey
No abstract text is available yet for this article.
August 2016: Gland Surgery
https://www.readbyqxmd.com/read/27539136/challenges-of-treating-incidental-synchronous-bilateral-breast-cancer-with-differing-tumour-biology
#11
Jonathan Walter Esclovon, Melissa Ponder, Nail Aydin, Subhasis Misra
A 59-year-old woman with right breast mass was diagnosed with invasive ductal carcinoma (IDC). Workup consisted of bilateral diagnostic mammogram and ultrasound (US); both showed a right breast mass with normal left breast. Core biopsy showed IDC with estrogen receptor negative (ER-)/progesterone receptor negative (PR-) and HER2/neu positive receptor status. The patient underwent carboplatin-based chemotherapy with Herceptin. The mass completely resolved. The patient desired to proceed with bilateral total mastectomy with right sentinel lymph node biopsy (SLNB)...
August 18, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27529090/women-s-preferences-for-contralateral-prophylactic-mastectomy-an-investigation-using-protection-motivation-theory
#12
Stephanie Tesson, Imogen Richards, David Porter, Kelly-Anne Phillips, Nicole Rankin, Toni Musiello, Michelle Marven, Phyllis Butow
OBJECTIVE: Most women diagnosed with unilateral breast cancer without BRCA1 or BRCA2 mutations are at low risk of contralateral breast cancer. Contralateral Prophylactic Mastectomy (CPM) decreases the relative risk of contralateral breast cancer, but may not increase life expectancy; yet international uptake is increasing. This study applied protection motivation theory (PMT) to determine factors associated with women's intentions to undergo CPM. METHODS: Three hundred eighty-eight women previously diagnosed with unilateral breast cancer and of negative or unknown BRCA1 or BRCA2 status were recruited from an advocacy group's research database...
May 2016: Patient Education and Counseling
https://www.readbyqxmd.com/read/27475088/bilateral-mastectomy-and-the-retreat-from-breast-conserving-surgery
#13
REVIEW
Frederick L Moffat, Danny Yakoub
The purpose of this study is to assess the consequences for breast cancer patients of the trend away from breast conservation in favor of bilateral and contralateral mastectomy. The methods are followed from the review of the literature from 1991 to 2015. Breast-conserving surgery and sentinel lymph node biopsy, introduced into mainstream practice in the 1980s and 1990s, respectively, are now the standard of care for early-stage breast cancer. Disruptive change has unexpectedly supervened in the guise of bilateral mastectomy for cancer or prophylaxis and contralateral prophylactic mastectomy...
August 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27469118/contralateral-prophylactic-mastectomy-consensus-statement-from-the-american-society-of-breast-surgeons-additional-considerations-and-a-framework-for-shared-decision-making
#14
Judy C Boughey, Deanna J Attai, Steven L Chen, Hiram S Cody, Jill R Dietz, Sheldon M Feldman, Caprice C Greenberg, Rena B Kass, Jeffrey Landercasper, Valerie Lemaine, Fiona MacNeill, Julie A Margenthaler, David H Song, Alicia C Staley, Lee G Wilke, Shawna C Willey, Katharine A Yao
No abstract text is available yet for this article.
October 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27469117/contralateral-prophylactic-mastectomy%C3%A2-cpm-consensus-statement-from-the-american-society-of-breast-surgeons-data-on-cpm-outcomes-and-risks
#15
Judy C Boughey, Deanna J Attai, Steven L Chen, Hiram S Cody, Jill R Dietz, Sheldon M Feldman, Caprice C Greenberg, Rena B Kass, Jeffrey Landercasper, Valerie Lemaine, Fiona MacNeill, David H Song, Alicia C Staley, Lee G Wilke, Shawna C Willey, Katharine A Yao, Julie A Margenthaler
No abstract text is available yet for this article.
October 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27465657/social-network-surgeon-and-media-influence-on-the-decision-to-undergo-contralateral-prophylactic-mastectomy
#16
Maria K Venetis, Erina L MacGeorge, Dadrie F Baptiste, Ashton Mouton, Lorin B Friley, Rebekah Pastor, Kristen Hatten, Janaka Lagoo, Monet W Bowling, Susan E Clare
OBJECTIVES: The rate of contralateral prophylactic mastectomy (CPM) has risen sharply in the past decade. The current study was designed to examine social network, surgeon, and media influence on patients' CPM decision-making, examining not only who influenced the decision, and to what extent, but also the type of influence exerted. METHODS: Patients (N=113) who underwent CPM at 4 Indiana University-affiliated hospitals between 2008 and 2012 completed structured telephone interviews in 2013...
July 26, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27465285/contralateral-prophylactic-mastectomy
#17
J R Benson, Z E Winters
No abstract text is available yet for this article.
September 2016: British Journal of Surgery
https://www.readbyqxmd.com/read/27382334/contralateral-prophylactic-mastectomy-current-perspectives
#18
REVIEW
Katharine Yao, Mark Sisco, Isabelle Bedrosian
There has been an increasing trend in the use of contralateral prophylactic mastectomy (CPM) in the United States among women diagnosed with unilateral breast cancer, particularly young women. Approximately one-third of women <40 years old are undergoing CPM in the US. Most studies have shown that the CPM trend is mainly patient-driven, which reflects a changing environment for newly diagnosed breast cancer patients. The most common reason that women choose CPM is based on misperceptions about CPM's effect on survival and overestimation of their contralateral breast cancer (CBC) risk...
2016: International Journal of Women's Health
https://www.readbyqxmd.com/read/27364506/contralateral-prophylactic-mastectomy-for-women-with-t4-locally-advanced-breast-cancer
#19
Brittany L Murphy, Tanya L Hoskin, Judy C Boughey, Amy C Degnim, Katrina N Glazebrook, Tina J Hieken
BACKGROUND: The use of contralateral prophylactic mastectomy (CPM) for women with unilateral breast cancer is increasing. The authors were interested in assessing whether this trend extended to patients with T4 disease. METHODS: We identified 92 patients from our prospective breast surgery registry with unilateral clinical T4 M0 disease who underwent mastectomy at our institution from October 2008 to July 2015. Patient, tumor, and treatment variables were compared between patients who did and those who did not undergo CPM, and the reasons patients elected CPM were ascertained...
October 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27355266/tradeoffs-associated-with-contralateral-prophylactic-mastectomy-in-women-choosing-breast-reconstruction-results-of-a-prospective-multicenter-cohort
#20
Adeyiza O Momoh, Wess A Cohen, Kelley M Kidwell, Jennifer B Hamill, Ji Qi, Andrea L Pusic, Edwin G Wilkins, Evan Matros
OBJECTIVE: Assess postoperative morbidity and patient-reported outcomes after unilateral and bilateral breast reconstruction in patients with unilateral breast cancer. BACKGROUND: Relatively little is known about the morbidity associated with and changes in quality of life experienced by patients who undergo contralateral prophylactic mastectomy (CPM) and breast reconstruction. This information would be valuable for decision making in patients with unilateral breast cancer...
June 28, 2016: Annals of Surgery
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