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Bilateral mastectomy

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https://www.readbyqxmd.com/read/29790359/-hereditary-breast-cancer-genetic-etiology-and-current-possibilities-of-prevention-and-surgical-treatment
#1
Alena Puchmajerová, Jannis Tornikidis, Lubor Mrňa, Markéta Havlovicová, Markéta Vlčková, Jana Chrudimská, Milan Macek, Jiří Hoch
Cancer is the second most common cause of death in our population just after cardiovascular diseases, since each third individual will become affected by it during their lifetime. Breast cancer is the most common malignancy in women. The lifetime cumulative risk of breast cancer in women under the age of 75 is around 8 % according to Czech statistics. In 70-75 % of all individuals sporadic breast carcinomas are found, with 5-10 % of all women suffer from the hereditary breast and ovarian cancer (HBOC) syndrome...
2018: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/29786129/surgeon-variability-and-factors-predicting-for-reoperation-following-breast-conserving-surgery
#2
Monica G Valero, Melissa Anne Mallory, Katya Losk, Mustafa Tukenmez, Jaeho Hwang, Kristen Camuso, Craig Bunnell, Tari King, Mehra Golshan
BACKGROUND: Reoperation after breast-conserving surgery (BCS) is common and has been partially associated with the lack of consensus on margin definition. We sought to investigate factors associated with reoperations and variation in reoperation rates across breast surgeons at our cancer center. METHODS: Retrospective analyses of patients with clinical stage I-II breast cancer who underwent BCS between January and December 2014 were conducted prior to the recommendation of 'no ink on tumor' margin...
May 21, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29778821/evaluating-mastectomy-skin-flap-necrosis-in-the-extended-breast-reconstruction-risk-assessment-score-for-one-year-prediction-of-prosthetic-reconstruction-outcomes
#3
Nora Hansen, Sasa Espino, Jordan T Blough, Michael M Vu, Neil A Fine, John Ys Kim
BACKGROUND: Rates of mastectomy for breast cancer treatment and immediate reconstruction continue to rise. With increasing scrutiny on outcomes and patient satisfaction, there is an impetus for providers to be more deliberate in deciding appropriate patient selection for breast reconstruction. The Breast Reconstruction Risk Assessment (BRA) Score was developed for prediction of complications after primary prosthetic breast reconstruction, focusing on calculating risk estimations for a variety of complications based on individual patient demographics and perioperative characteristics...
May 17, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29774312/breast-cancer-prevention-current-approaches-and-future-directions
#4
REVIEW
Edward R Sauter
The topic of breast cancer prevention is very broad. All aspects of the topic, therefore, cannot be adequately covered in a single review. The objective of this review is to discuss strategies in current use to prevent breast cancer, as well as potential approaches that could be used in the future. This review does not discuss early detection strategies for breast cancer, including breast cancer screening. The breast is the most common site among women worldwide of noncutaneous cancer. Many clinical and genetic factors have been found to increase a woman's risk of developing the disease...
April 2018: European journal of breast health
https://www.readbyqxmd.com/read/29772993/shoulder-lesion-in-a-69-year-old-woman
#5
Andrew J Hayden, Srinivas Kolla, Adele L Boskey, Steven Burekhovich, Chuanyong Lu, Michael Stracher, Aditya V Maheshwari
Milwaukee Shoulder Syndrome (MSS) is a painful progressive arthropathy in which hydroxyapatite crystal deposition in synovial tissue induces lysosomal release of collagenase and neutral proteases. These enzymes are destructive to periarticular tissue, including the synovium, articular cartilage, rotator cuff muscles, and the intrasynovial cortical bone. MSS predominantly occurring in women (90%) over the age of 70 years of age with a clinical history marked by recurrent joint effusions and pain, which classically worsens at night...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29772965/association-of-surgical-approach-with-complication-rate-progression-free-survival-time-and-disease-specific-survival-time-in-cats-with-mammary-adenocarcinoma-107-cases-1991-2014
#6
Francesco Gemignani, Philipp D Mayhew, Michelle A Giuffrida, Jason Palaigos, Jeffrey J Runge, David E Holt, Nicholas A Robertson, Bernard Seguin, Meaghan Walker, Ameet Singh, Julius M Liptak, Giorgio Romanelli, Marina Martano, Sarah E Boston, Cassie Lux, Roberto Busetto, William T N Culp, Katherine A Skorupski, Jenna H Burton
OBJECTIVE To evaluate potential associations between surgical approach and complication rate, progression-free survival time, and disease-specific survival time in cats with mammary adenocarcinoma. DESIGN Retrospective case series. ANIMALS 107 client-owned cats. PROCEDURES Medical records of cats that underwent surgical excision of mammary adenocarcinoma by means of a unilateral or bilateral (staged or single-session) mastectomy at 9 hospitals between 1991 and 2014 were reviewed. Relevant clinicopathologic data and details of surgical and adjuvant treatments were recorded...
June 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29764822/numb-chin-syndrome-an-ominous-sign-of-mandibular-metastasis
#7
Abdul Razak, Bee See Goh, Jothi Raamahlingam Rajaran, Abd Jabar Nazimi
A 51-year-old woman a known case of stage 2 breast carcinoma in 2006 and underwent left mastectomy performed in the same year presented with bilateral lower limb pain suggestive of spinal pathology, and left chin numbness, both of 2 weeks' duration. Examination revealed left mandibular hypoesthesia without any other sign or symptoms. Orthopantomogram was unremarkable apart from mild alveolar bone expansion at tooth 36 area, which was extracted 3 months earlier. Subsequently, a full-body positron emission tomography contrast enhanced computer tomography revealed hypermetabolic lesions of her axial (excluding skull) and appendicular skeleton...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29761322/concurrent-risk-reduction-surgery-in-patients-with-increased-lifetime-risk-for-breast-and-ovarian-cancer-an-analysis-of-the-national-surgical-quality-improvement-program-nsqip-database
#8
Maryam Elmi, Arash Azin, Ahmad Elnahas, David R McCready, Tulin D Cil
BACKGROUND: Patients with genetic susceptibility to breast and ovarian cancer are eligible for risk-reduction surgery. Surgical morbidity of risk-reduction mastectomy (RRM) with concurrent bilateral salpingo-oophorectomy (BSO) is unknown. Outcomes in these patients were compared to patients undergoing RRM without BSO using a large multi-institutional database. METHODS: A retrospective cohort analysis was conducted using the American College of Surgeon's National Surgical Quality Improvement Program (NSQIP) 2007-2016 datasets, comparing postoperative morbidity between patients undergoing RRM with patients undergoing RRM with concurrent BSO...
May 14, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29758504/patients-perspectives-and-experiences-concerning-barriers-to-accessing-information-about-bilateral-prophylactic-mastectomy
#9
Rachael Glassey, Moira O'Connor, Angela Ives, Christobel Saunders, kConFab Investigators, Sarah O'Sullivan, Sarah J Hardcastle
PURPOSE: To explore the barriers and experiences of accessing information for women who have received genetic risk assessment/testing results for breast cancer (BC) and are considering a bilateral prophylactic mastectomy (BPM) and, exploring participants' preferences concerning information and support needs. METHODS: A qualitative retrospective study guided by interpretative phenomenological analysis was utilised. Semi-structured interviews were conducted with forty-six women who were either considering BPM or had already undergone the surgery...
May 11, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29752634/bilateral-mastectomy-as-radical-treatment-of-gynecomastia-secondary-to-antiretroviral-therapy-in-a-low-income-setting-a-case-report
#10
Mario Antunes, Marcella Schiavone, Damiano Pizzol, Francesco Di Gennaro, Rossana Ludovico, Angela De Palma
Gynecomastia is a common finding in males, with an incidence that varies widely globally. In 10-25% of cases, it is caused by drugs. Its pathophysiologic mechanism includes exposure to exogenous estrogens and medications that cause hypogonadism, antiandrogenic effects and hyperprolactinemia. Gynecomastia is associated with exposure to antiretroviral therapy (ART), particularly efavirenz. Sometimes surgery may be required as treatment. We report a case of a 46-year-old man receiving ART presenting with a marked bilateral breast enlargement who underwent bilateral mastectomy as the only successful treatment in a low-income setting...
May 11, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29752327/adherence-to-guidelines-for-breast-surveillance-in-breast-cancer-survivors
#11
Kathryn J Ruddy, Lindsey Sangaralingham, Rachel A Freedman, Sarah Mougalian, Heather Neuman, Caprice Greenberg, Ahmedin Jemal, Narjust Duma, Tufia C Haddad, Valerie Lemaine, Karthik Ghosh, Tina J Hieken, Katie Hunt, Celine Vachon, Cary Gross, Nilay D Shah
Background: Guidelines recommend annual mammography after curative-intent treatment for breast cancer. The goal of this study was to assess contemporary patterns of breast imaging after breast cancer treatment. Methods: Administrative claims data were used to identify privately insured and Medicare Advantage beneficiaries with nonmetastatic breast cancer who had residual breast tissue (not bilateral mastectomy) after breast surgery between January 2005 and May 2015. We calculated the proportion of patients who had a mammogram, MRI, both, or neither during each of 5 subsequent 13-month periods...
May 2018: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29746276/deepithelialized-skin-reduction-preserves-skin-and-nipple-perfusion-in-immediate-reconstruction-of-large-and-ptotic-breasts
#12
Danielle H Rochlin, Dung H Nguyen
BACKGROUND: Women with large and/or ptotic breasts are often not considered candidates for nipple-sparing mastectomy (NSM) and/or immediate breast reconstruction given difficulties avoiding ischemic complications and achieving a favorable aesthetic result. We report a novel technique involving deepithelialized skin reduction to simultaneously reduce the skin envelope and preserve perfusion to the skin and nipple in immediate breast reconstruction for women that fit this high-risk anatomic profile...
April 30, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29744328/bilateral-metachronous-breast-carcinoma-a-rare-case-report
#13
Anand Singla, Navneet Kaur, Darshanjeet Singh Walia, Deeksha Singla
The occurrence of bilateral breast cancer is rare. A second primary in the contralateral breast can either be synchronous or metachronous. Lobular carcinoma of the breast is known for its multicentricity and bilateral spread. The synchronous mixed pattern of carcinoma of the breast has also been reported in the same breast. The family history of breast carcinoma, estrogen receptor negativity, and human epidermal growth factor receptor-2 positivity are risk factors for the development of contralateral breast malignancy...
April 2018: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29725545/single-stage-nipple-sparing-mastectomy-and-reduction-mastopexy-in-the-ptotic-breast
#14
M E Pontell, N Saad, A Brown, M Rose, R Ashinoff, A Saad
Purpose: Given the proposed increased risk of nipple-areolar complex (NAC) necrosis, nipple-sparing mastectomy (NSM) is generally not recommended for patients with large or significantly ptotic breasts. NAC preserving strategies in this subgroup include staged or simultaneous NSM and reduction mastopexy. We present a novel approach towards simultaneous NSM and reduction mastopexy in patients with large, ptotic breasts. Methods: Literature pertaining to NSM for women with large, ptotic breasts was reviewed and a surgical approach was designed to allow for simultaneous NSM and reduction mastopexy in such patients...
2018: Plastic Surgery International
https://www.readbyqxmd.com/read/29721054/international-consensus-on-the-clinical-management-of-inflammatory-breast-cancer-from-the-morgan-welch-inflammatory-breast-cancer-research-program-10th-anniversary-conference
#15
Naoto T Ueno, Jose Rodrigo Espinosa Fernandez, Massimo Cristofanilli, Beth Overmoyer, Dan Rea, Fedor Berdichevski, Mohamad El-Shinawi, Jennifer Bellon, Huong T Le-Petross, Anthony Lucci, Gildy Babiera, Sarah M DeSnyder, Mediget Teshome, Edward Chang, Bora Lim, Savitri Krishnamurthy, Michael C Stauder, Simrit Parmar, Mona M Mohamed, Angela Alexander, Vicente Valero, Wendy A Woodward
National and international experts in inflammatory breast cancer (IBC) from high-volume centers treating IBC recently convened at the 10th Anniversary Conference of the Morgan Welch Inflammatory Breast Cancer Research Program at The University of Texas MD Anderson Cancer Center in Houston Texas. A consensus on the clinical management of patients with IBC was discussed, summarized, and subsequently reviewed. All participants at the conference (patients, advocates, researchers, trainees, and clinicians) were queried using the MDRing electronic survey on key management issues...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29713993/influences-on-satisfaction-with-reconstructed-breasts-and-intimacy-in-younger-women-following-bilateral-prophylactic-mastectomy-a-qualitative-analysis
#16
Rachael Glassey, Moira O'Connor, Angela Ives, Christobel Saunders, Sarah J Hardcastle
PURPOSE: The aim of this study was to explore the influences on satisfaction with reconstructed breasts and intimacy following bilateral prophylactic mastectomy (BPM) in younger women (< 35) with a strong family history of breast cancer. METHODS: Twenty-six women who had undergone BPM between 1 and6 years ago were recruited from New Zealand and Australia through a genetics clinic, registry, research cohort, and online (Mage  = 31). Twenty-three were BRCA mutation carriers...
April 30, 2018: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29707442/the-functional-impact-of-breast-reconstruction-an-overview-and-update
#17
Jonas A Nelson, Iris T Lee, Joseph J Disa
As rates of bilateral mastectomy and immediate reconstruction rise, the aesthetic and psychosocial benefits of breast reconstruction are increasingly well understood. However, an understanding of functional outcome and its optimization is still lacking. This endpoint is critical to maximizing postoperative quality of life. All reconstructive modalities have possible functional consequences. Studies demonstrate that implant-based reconstruction impacts subjective movement, but patients' day-to-day function may not be objectively hindered despite self-reported disability...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29690864/radiogenic-angiosarcoma-of-the-breast-case-report-and-systematic-review-of-the-literature
#18
Askin Dogan, Peter Kern, Beate Schultheis, Günther Häusler, Günther A Rezniczek, Clemens B Tempfer
BACKGROUND: Radiogenic angiosarcoma of the breast (RASB) is a rare late sequela of local irradiation of the breast or chest wall after breast cancer. The prognosis of women with RASB is poor and there is no standardized therapy for this type of malignancy. CASE PRESENTATION: We present the case of a 54 year old woman with RASB (poorly differentiated angiosarcoma of the left breast; pT1, pNX, M0, L0, V0) and a history of invasive-ductal cancer of the left breast (pT1b, G2, pN0, ER positive, PR positive, HER-2/neu negative) treated in July 2012 with breast-conserving surgery, adjuvant chemotherapy with 6 cycles of epirubicin and cyclophosphamide, adjuvant irradiation of the left breast with 50 Gray, and adjuvant endocrine therapy with an aromatase inhibitor...
April 24, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29687179/bilateral-mastectomies-can-a-co-surgeon-technique-offer-improvements-over-the-single-surgeon-method
#19
Melissa Anne Mallory, Constantine Tarabanis, Eric Schneider, Suniti Nimbkar, Mehra Golshan
PURPOSE: Bilateral mastectomy (BM) is traditionally performed using a single-surgeon (SS) technique (SST); a co-surgeon (CS) technique (CST), where each attending surgeon concurrently performs a unilateral mastectomy, offers an alternative approach. We sought to compare the CST and SST for BM with respect to operative times and complications. METHODS: Patients undergoing BM without reconstruction at our institution between 2005 and 2015 were identified using operative caselogs and stratified into CS- and SS-cohorts...
April 23, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29650917/-a-case-of-primary-spinddle-cell-carcinoma-of-the-breast
#20
Hiroshi Kawai, Chihiro Yoshikawa, Kento Kawasaki, Norichika Iga, Ryosuke Yoshida, Naohisa Waki, Futoshi Uno, Masahiro Ishizaki, Hideyuki Nishi, Kazuki Yamashita, Shinichiro Miyoshi
A 76-year-old female underwent breast-conserving surgery of the right breast and sentinel lymph node biopsy for primary breast cancer. Three years later, mammography and ultrasonography showed a small nodule in the right breast. There was nothing abnormal in the left breast. Three months later, she complained of a huge and rapid growing mass in the left breast. Malignant cells were obtained on fine needle aspiration biopsy in the right breast tumor. But it was not possible to diagnose whether the left breast tumor was benign or malignant on fine needle aspiration biopsy and needle biopsy...
March 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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