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Clinical pearl

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https://www.readbyqxmd.com/read/28697040/navigating-the-cervical-cancer-screening-guidelines-for-women-aged-older-than-65-years
#1
Taniqua A Miller, Lisa Flowers
One of the most notable changes stemming from consensus guidance in 2012 is cessation of cervical cancer screening in low-risk women aged older than 65 years. Despite evidence provided for this recommendation, implementation in clinical practice can be challenging, with resistance from patients and providers. This NAMS Practice Pearl reviews data supporting this recommendation and provides clinicians with confidence as we counsel our patients.
July 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28697035/caring-for-the-lesbian-patient-at-midlife-and-beyond
#2
Jordan E Rullo, Stephanie S Faubion
Clinicians who have an understanding of lesbian women and their unique stressors, who provide a welcoming and inclusive environment, and who provide cross-cultural care are well positioned to reduce healthcare stigma and improve clinical outcomes. This Practice Pearl addresses these issues, focusing on the lesbian patient at midlife and beyond.
July 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28694045/myelitis-in-systemic-lupus-erythematosus
#3
REVIEW
Xiang-Yang Li, Hai-Bing Xiao, Pearl Pai
SLE-associated acute transverse myelitis (ATM) is a rare, but potentially severe complication of Systemic lupus erythematosus (SLE), and may lead to significant motor, sensory and autonomic dysfunctions in the central nervous system resulting in marked neurological deficits. It is important to recognize its clinical feature to allow timely diagnosis and management of this condition. In this review, we aimed to provide the reader with the understanding of its clinical presentation and classification, the underlying pathological, MRI (magnetic resonance imaging) appearance, and current status of management, with an emphasis on recent discoveries and advancements...
July 7, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28691593/electrographic-seizures-in-preterm-neonates-in-the-neonatal-intensive-care-unit
#4
Ersida Buraniqi, Arnold J Sansevere, Kush Kapur, Ann M Bergin, Phillip L Pearl, Tobias Loddenkemper
OBJECTIVE: Characterize clinical and electroencephalography (EEG) characteristics of preterm neonates undergoing continuous EEG in the neonatal intensive care unit. METHODS: Retrospective study of preterm neonates born less than 37 weeks' gestational age undergoing continuous EEG in the neonatal intensive care unit at Boston Children's Hospital over a 2-year period. RESULTS: Fifty-two preterms (46% male) had a mean gestational age of 32.8 weeks (standard deviation = 4...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28678302/clinical-pearls-laboratory-assessments-of-direct-oral-anticoagulants-doacs
#5
Robert C Gosselin, Robert Gosselin, Jonathan Douxfils, Dorothy Adcock
Direct oral anticoagulants (DOACS) are being used for stroke prevention in patients with atrial fibrillation as well as for prophylaxis and treatment of venous thromboembolism. Clinicians who treat, or may encounter, patients with DOAC exposure, should be aware of the limitations of coagulation testing in this setting, and seek counsel from their laboratory to understand the effects of DOACS on coagulation results. Generally, assays that employ clot based principles, or methods that require thrombin or Factor Xa activation or substrates may be affected by the presence of DOACS...
July 5, 2017: Hämostaseologie
https://www.readbyqxmd.com/read/28676895/analysis-of-normal-and-dysplastic-glenohumeral-morphology-at-magnetic-resonance-imaging-in-children-with-neonatal-brachial-plexus-palsy
#6
Fabian van de Bunt, Michael L Pearl, Eric K Lee, Lauren Peng, Paul Didomenico
BACKGROUND: Glenoid version and percentage of the humeral head anterior to the scapular line are commonly used 2-D measures to assess deformity of the glenohumeral joint of children with neonatal brachial plexus palsy. OBJECTIVE: To assess whether glenoid version and percentage of the humeral head anterior to the scapular line would be altered by standardizing the measurements to the orientation of the scapula. MATERIALS AND METHODS: Twenty-one bilateral magnetic resonance imaging (MRI) scans were evaluated by four reviewers...
July 4, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28668910/clinical-pearls
#7
EDITORIAL
Rhonda Board
No abstract text is available yet for this article.
July 2017: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/28668112/pearls-and-pitfalls-autoimmune-lymphoproliferative-syndrome-and-autoimmune-lymphoproliferative-syndrome-like-disease
#8
Anne K Bartels, Taylor A Banks, Jeannie L Bay
A case of autoimmune lymphoproliferative syndrome (ALPS) was presented, followed by a discussion of the clinical characteristics, pathophysiology, diagnosis, and management of this disease. Clinical pearls and pitfalls are emphasized for the use of the practicing allergist and the fellow in-training. The diagnosis of ALPS was guided by published criteria. A careful history and workup were needed to exclude other possible etiologies for the patient's symptoms and physical findings. ALPS often carries significant morbidity and is best managed through a multidisciplinary approach...
July 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28660153/vascular-diseases-of-the-spleen-a-review
#9
REVIEW
Pearl Princess D Uy, Denise Marie Francisco, Anshu Trivedi, Michael O'Loughlin, George Y Wu
Vascular diseases of the spleen are relatively uncommon in the clinical practice. However, the reported incidence has been progressively increasing, probably due to advances in the imaging modalities used to detect them. This disease condition often presents with non-specific clinical manifestations, but can be associated with significant morbidity and mortality. This review article aims to provide updated clinical information on the different vascular diseases of the splenic vasculature-splenic vein thrombosis, splenic vein aneurysm, splenic artery aneurysm, splenic arteriovenous fistula, and spontaneous splenorenal shunt-in order to aid clinicians in early diagnosis and management...
June 28, 2017: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/28658251/hiv-disease-progression-among-women-following-seroconversion-during-a-tenofovir-based-hiv-prevention-trial
#10
Sharon A Riddler, Marla Husnik, Gita Ramjee, Anamika Premrajh, Bomkazi Onini Tutshana, Arendevi Pather, Samantha Siva, Nitesha Jeenarain, Gonasagrie Nair, Pearl Selepe, Samuel Kabwigu, Thesla Palanee-Phillips, Ravindre Panchia, Felix Mhlanga, Lisa Levy, Edward Livant, Karen Patterson, Vanessa Elharrar, Jennifer Balkus
BACKGROUND: Little is known regarding HIV disease outcomes among individuals who become infected with HIV while receiving antiretroviral medications for prevention. We compared HIV disease parameters among women who seroconverted while receiving tenofovir-containing oral or vaginal pre-exposure prophylaxis (PrEP) to placebo. METHODS: Participants with HIV seroconversion in a randomized placebo-controlled trial of oral tenofovir, oral tenofovir/emtricitabine, and vaginal tenofovir gel (MTN-003) were followed in a longitudinal cohort study (MTN-015)...
2017: PloS One
https://www.readbyqxmd.com/read/28651691/clinical-pearls-in-women-s-health
#11
Stephanie S Faubion, Scott C Litin, John B Bundrick
No abstract text is available yet for this article.
June 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28651690/clinical-pearls-in-pulmonary-diseases
#12
Craig E Daniels, Scott C Litin, John B Bundrick
No abstract text is available yet for this article.
June 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28651689/clinical-pearls-in-palliative-medicine
#13
Molly A Feely, Scott C Litin, John B Bundrick
No abstract text is available yet for this article.
June 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28651688/clinical-pearls-in-infectious-diseases-2017
#14
Randall S Edson, Scott C Litin, John B Bundrick
No abstract text is available yet for this article.
June 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28651687/clinical-pearls-in-geriatrics
#15
Ericka E Tung, Scott C Litin, John B Bundrick
No abstract text is available yet for this article.
June 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28628728/characterizing-the-detection-threshold-for-optical-imaging-in-surgical-oncology
#16
Andrew C Prince, Aditi Jani, Melissa Korb, Kiranya E Tipirneni, Benjamin B Kasten, Eben L Rosenthal, Jason M Warram
BACKGROUND AND OBJECTIVES: Optical imaging to guide cancer resections is rapidly transitioning into the operating room. However, the sensitivity of this technique to detect subclinical disease is yet characterized. The purpose of this study was to determine the minimum range of cancer cells that can be detected by antibody-based fluorescence imaging. METHODS: 2LMP (breast), COLO-205 (colon), MiaPaca-2 (pancreas), and SCC-1 (head and neck) cells incubated in vitro with cetuximab-IRDye800CW (dose range 8...
June 19, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28619191/outcomes-of-pci-in-relation-to-procedural%C3%A2-characteristics-and-operator%C3%A2-volumes-in%C3%A2-the-united-states
#17
Alexander C Fanaroff, Pearl Zakroysky, David Dai, Daniel Wojdyla, Matthew W Sherwood, Matthew T Roe, Tracy Y Wang, Eric D Peterson, Hitinder S Gurm, Mauricio G Cohen, John C Messenger, Sunil V Rao
BACKGROUND: Professional guidelines have reduced the recommended minimum number to an average of 50 percutaneous coronary intervention (PCI) procedures performed annually by each operator. Operator volume patterns and associated outcomes since this change are unknown. OBJECTIVES: The authors describe herein PCI operator procedure volumes; characteristics of low-, intermediate-, and high-volume operators; and the relationship between operator volume and clinical outcomes in a large, contemporary, nationwide sample...
June 20, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28602902/case-report-a-durable-open-repair-of-a-rare-profunda-aneurysm
#18
Pouria Parsa, Anthony Rios, Kristha Cantu, John Eidt, Dennis Gable, Gregory Pearl
Profunda femoris artery aneurysms (PFAAs) are rare and difficult to diagnose in the early stages of development due to location and encasement in the deep thigh musculature. We report the case of a 74-year-old male who was discovered to have a right PFAA during evaluation for progressively worsening short distance claudication. He had undergone an angioplasty of the left iliofemoral system several months ago with no improvement of his symptoms. The PFAA was diagnosed through CT angiography and repaired via syndactylization of profunda femoris branches and interposition grafting with a polytetrafluoroethylene stretch graft...
June 7, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28600298/trematodal-granulomatous-uveitis-in-paediatric-egyptian-patients-a-case-series
#19
Amin Rm, Goweida Mb, El Goweini Hf, Bedda Am, Lotfy Wm, Gaballah Ah, Nadar Aa, Radwan Ae
PURPOSE: To describe the clinical presentations and results of laboratory analysis of waterborne ophthalmic granulomas of the anterior chamber (AC) in Egyptian patients. PARTICIPANTS: 110 patients with granulomatous anterior uveitis and distinctive AC nodules. DESIGN: Prospective, non-comparative, case series. METHODS: Demographic data including age, gender and place of residence were recorded. A full ophthalmic examination with emphasis on the inflammatory characteristics and systemic workup was performed...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28578761/research-pearls-the-significance-of-statistics-and-perils-of-pooling
#20
EDITORIAL
Aman Dhawan, Jefferson C Brand, Matthew T Provencher, Michael J Rossi, James H Lubowitz
A series of articles on statistics are intended for an audience of clinicians, as well as statisticians and authors. Statistical significance is different than clinical significance. Understanding of clinical outcomes, value, quality, or generalizability requires critical analysis of medical research literature to ensure that statistical analyses have been properly applied and interpreted.
June 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
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