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https://www.readbyqxmd.com/read/27924381/dual-energy-x-ray-absorptiometry-and-fracture-prediction-in-patients-with-spinal-cord-injuries-and-disorders
#1
L Abderhalden, F M Weaver, M Bethel, H Demirtas, S Burns, J Svircev, H Hoenig, K Lyles, S Miskevics, L D Carbone
: Low T-scores at the hip predict incident fractures in persons with a SCI. INTRODUCTION: Persons with a spinal cord injury (SCI) have substantial morbidity and mortality following osteoporotic fractures. The objective of this study was to determine whether dual-energy X-ray absorptiometry (DXA) measurements predict osteoporotic fractures in this population. METHODS: A retrospective historical analysis that includes patients (n = 552) with a SCI of at least 2 years duration who had a DXA performed and were in the VA Spinal Cord Disorders Registry from fiscal year (FY) 2002-2012 was performed...
December 6, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27924380/adherence-to-the-2006-american-heart-association-s-diet-and-lifestyle-recommendations-for-cardiovascular-disease-risk-reduction-is-associated-with-bone-mineral-density-in-older-chinese
#2
G D Chen, D Ding, H Y Tian, Y Y Zhu, W T Cao, C Wang, Y M Chen
: This cross-sectional study investigated the association between the modified 2006 American Heart Association Diet and Lifestyle Recommendations (AHA-DLR) and bone mineral density in Chinese adults. We found that better adherence to the AHA-DLR associated with higher bone mineral density (BMD) at multiple sites. INTRODUCTION: Accumulating evidence shows that cardiovascular disease (CVD) and osteoporosis are associated with each other, yet little research has focused on whether strategies to reduce CVD risk could also benefit bone health...
December 6, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27921206/periacetabular-osteotomy-provides-higher-survivorship-than-rim-trimming-for-acetabular-retroversion
#3
Corinne A Zurmühle, Helen Anwander, Christoph E Albers, Markus S Hanke, Simon D Steppacher, Klaus A Siebenrock, Moritz Tannast
BACKGROUND: Acetabular retroversion can cause impaction-type femoroacetabular impingement leading to hip pain and osteoarthritis. It can be treated by anteverting periacetabular osteotomy (PAO) or acetabular rim trimming with refixation of the labrum. There is increasing evidence that acetabular retroversion is a rotational abnormality of the entire hemipelvis and not a focal overgrowth of the anterior acetabular wall, which favors an anteverting PAO. However, it is unknown if this larger procedure would be beneficial in terms of survivorship and Merle d'Aubigné scores in a midterm followup compared with rim trimming...
December 5, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27920807/underdiagnosis-of-osteoporotic-vertebral-fractures-in-patients-with-fragility-fractures-retrospective-analysis-of-over-300-patients
#4
Vanna Bottai, Stefano Giannotti, Gloria Raffaetà, Maurizio Mazzantini, Francesco Casella, Gaia De Paola, Agnese Menconi, Francesca Falossi, Giulio Guido
Osteoporosis (OP) is a silent disease unless a fracture occurs; it is a major health problem, mainly due to fragility fractures, that occur at vertebral and peripheral sites. Vertebral fractures (VF) are probably the most common fragility fractures, but they go often unrecognized. The main clinical symptoms of VF are acute and chronic back pain, spinal deformity, reduced mobility and impaired quality of life. They are frequently associated with other fragility fractures. We examined 478 patients at our outpatient clinic, who were referred for fragility fracture occurrence...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27920805/abaloparatide
#5
REVIEW
Stefano Gonnelli, Carla Caffarelli
Abaloparatide is an investigational analog of human PTHrP (1-34) being developed for the treatment of osteoporosis. The amino-acid sequence of abaloparatide is identical to that of PTHrP in the first 20 amino-acids, while over half of the remaining amino-acids are different. Some studies in animals and in humans reported that abaloparatide presented a potent anabolic activity with reduced effects on bone resorption as compared to that observed with teriparatide. This may be due to a more transient signaling response of abaloparatide related to differing affinities of the two drugs to the specific conformations of the PTH1 receptor...
May 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/27919248/bone-mineral-density-in-patients-with-multiple-sclerosis-hereditary-ataxia-or-hereditary-spastic-paraplegia-after-at-least-10%C3%A2-years-of-disease-a-case-control-study
#6
Cecilia Smith Simonsen, Elisabeth Gulowsen Celius, Cathrine Brunborg, Chantal Tallaksen, Erik Fink Eriksen, Trygve Holmøy, Stine Marit Moen
BACKGROUND: Although disability is considered the main cause of low bone mineral density (BMD) in multiple sclerosis (MS), other factors related to the disease process or treatment could also be involved. The aim of this study was to assess whether patients with MS are more likely to develop low BMD (osteopenia or osteoporosis) than patients with the non-inflammatory neurological diseases Hereditary Spastic Paraplegia (HSP) and Hereditary Ataxia (HA). METHODS: We performed a case control study comparing BMD (spine, hip and total body) and biochemical measures of bone metabolism in 91 MS patients and 77 patients with HSP or HA, matched for age, gender and disability...
December 5, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27919200/bony-ankylosis-of-the-facet-joint-of-the-cervical-spine-in-rheumatoid-arthritis-its-characteristics-and-relationship-to-the-clinical-findings
#7
Haku Iizuka, Yoichi Iizuka, Koichi Okamura, Yukio Yonemoto, Tokue Mieda, Kenji Takagishi
OBJECTIVES: The purpose of this study was to clarify the characteristics of bony ankylosis of the facet joint of the cervical spine in RA patients who required cervical spine surgery, and its relationship to the clinical findings. METHODS: Eighty consecutive RA patients with cervical spine disorder who received initial surgery were reviewed. The occurrence of bony ankylosis of the facet joint of the cervical spine was investigated using computed tomography (CT) before surgery...
December 6, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27914693/high-prevalence-of-osteoporosis-and-morphometric-vertebral-fractures-in-indian-males-aged-60-years-and-above-should-age-for-screening-be-lowered
#8
Khurshid A Bhat, Manisha Kakaji, Ashish Awasthi, Manoj Shukla, Manoj Dubey, Rajesh Srivastava, Uttam Singh, Sushil K Gupta
Current guidelines recommend bone mineral density (BMD) measurement in asymptomatic men above age 70 years and vertebral fracture (VF) assessment above 80 years with T-score <-1.0 with risk factors. We studied the prevalence of osteoporosis and morphometric VF in asymptomatic males aged 60 years and above in North India. Free-living community-dwelling men (n = 241, age: mean ± standard deviation 68.0 ± 6.2 years) underwent a detailed history, physical examination, biochemical evaluation, and BMD measurements at 3 sites: lumbar spine, total hip (TH), and femoral neck (FN)...
November 30, 2016: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/27908253/assessment-of-bone-quality-in-osteoporosis-treatment-with-bone-anabolic-agents-really-something-new
#9
Fabio Massimo Ulivieri, Renata Caudarella, Marzia Camisasca, Daniela Maria Cabrini, Ilaria Merli, Carmelo Messina, Luca Petruccio Piodi
Osteoporosis is a chronic pathologic condition, particularly of the elderly, in which a reduction of bone mineral density (BMD) weakens bone, leading to the so-called fragility fractures, most often of spine and femur. The gold standard exam for the quantitative measurement of BMD is the dual X-ray photon absorptiometry (DXA), a radiological method. However, a relevant number of fragility fractures occurs in the range of normal BMD values, meaning that also qualitative aspects of bone play a role, namely bone architecture and bone geometry...
December 1, 2016: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/27907000/whole-body-vibration-treatments-in-postmenopausal-women-can-improve-bone-mineral-density-results-of-a-stimulus-focussed-meta-analysis
#10
Antonio Fratini, Tecla Bonci, Anthony M J Bull
Whole body vibration treatment is a non-pharmacological intervention intended to stimulate muscular response and increase bone mineral density, particularly for postmenopausal women. The literature related to this topic is controversial, heterogeneous, and unclear despite the prospect of a major clinical effect.The aim of this study was to identify and systematically review the literature to assess the effect of whole body vibration treatments on bone mineral density (BMD) in postmenopausal women with a specific focus on the experimental factors that influence the stimulus...
2016: PloS One
https://www.readbyqxmd.com/read/27900426/the-lumbar-spine-age-related-degenerative-disease-influences-the-bmd-not-the-tbs-the-osteolaus-cohort
#11
I Padlina, E Gonzalez-Rodriguez, D Hans, M Metzger, D Stoll, B Aubry-Rozier, O Lamy
: We evaluated the influence of degenerative disease and fractured vertebra on lumbar spine bone mineral density (BMD) and trabecular bone score (TBS) in 1500 women aged 50-80 years. TBS was not affected by a degenerative disease. While BMD increases after 62.5 years, TBS continues to decline. TBS should play a leading role in lumbar spine evaluation. INTRODUCTION: After menopause, lumbar spine (LS) BMD and TBS values decrease. Degenerative disease (DD) increases with age and affect LS BMD...
November 30, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27896435/course-of-pelvic-lift-during-total-hip-arthroplasty
#12
Steffen Brodt, Dimitri Nowack, Linda Krakow, Christoph Windisch, Georg Matziolis
INTRODUCTION: The position of the cup makes a major contribution to the success of total hip arthroplasty (THA). In conventional implantation of the prosthesis without navigation, the surgeon relies on the spatial position of the pelvis. However, iatrogenic manipulation of the pelvis during different surgical steps constantly changes the position of the pelvis during the operation. The position of the pelvis is substantial for the correct placement of the cup. The objective of this study was to investigate and visualize the course of this pelvic lift and correlate it to certain surgical steps...
November 28, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27896362/the-association-between-urinary-sodium-to-potassium-ratio-and-bone-density-in-middle-aged-chinese-adults
#13
W T Cao, J He, G D Chen, C Wang, R Qiu, Y M Chen
: The joint effect of sodium and potassium on bone health remains uncertain. We examined the associations between urinary excretion of sodium, potassium, and their ratio and bone mineral density (BMD), and reported an inverse association between urinary sodium-to-potassium ratio and BMD in women, but not in men. INTRODUCTION: Several studies have suggested that a higher sodium or lower potassium intake is associated with poor bone health. However, few studies have examined their joint effects...
November 28, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27896193/multidisciplinary-approach-to-an-extended-pressure-sore-at-the-lumbosacral-area
#14
Sehoon Yoon, Euicheol Jeong, Hudson Alex Lázaro
A pressure sore wound is often extensive or complicated by local infection involving adjacent soft tissue and bone. In this case, a regional flap after simple debridement is not adequate. Here, we present a case of an extensive pressure sore in the sacral area with deep tissue infection. A 43-year-old female patient with a complicated sore with deep tissue infection had a presacral abscess, an iliopsoas abscess, and an epidural abscess in the lumbar spine. After a multidisciplinary approach performed in stages, the infection had subsided and removal of the devitalized tissue was possible...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27889047/sex-differences-in-the-association-between-stroke-and-bone-mineral-density-in-elderly-koreans-the-korean-national-health-and-nutrition-examination-survey-2008-2010
#15
Ji Eun Lee, Hye-Rim Jeon, Jung Keun Park, Kyung-Do Han, Ji-Hyun Kim, Jinnie Yoon, Seok-Won Park, Yang-Hyun Kim, Kyung-Hwan Cho
OBJECTIVES: The aim of this study was to investigate whether osteoporosis is more prevalent in elderly Korean people who have had a stroke and whether the association differs by sex. STUDY DESIGN: A total of 3806 elderly subjects (1951 men and 1855 women) from the Korea National Health and Nutrition Examination Survey were included in this study. Stroke history was determined by self-administered questionnaire. Bone mineral density (BMD) was measured at the lumbar spine, total hip, and neck of the femur using dual-energy X-ray absorptiometry...
January 2017: Maturitas
https://www.readbyqxmd.com/read/27888285/efficacy-of-statins-for-osteoporosis-a-systematic-review-and-meta-analysis
#16
REVIEW
T An, J Hao, S Sun, R Li, M Yang, G Cheng, M Zou
Our meta-analysis assessed the efficacy of statins on the risk of fracture, bone mineral density (BMD), and the markers of bone metabolism by collecting data from 33 clinical trials. We found that statin treatment was associated with bone metabolism. And statins seemed to be more effective on male patients with osteoporosis. The efficacy of statins for the treatment of osteoporosis has been controversial in previous studies and meta-analyses. Our meta-analysis was conducted to examine in detail the efficacy of statins on osteoporosis...
November 25, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27887681/bone-accrual-in-males-with-autism-spectrum-disorder
#17
Ann M Neumeyer, Natalia Cano Sokoloff, Erin McDonnell, Eric A Macklin, Christopher J McDougle, Madhusmita Misra
OBJECTIVE: To test the hypothesis that bone accrual over a 4-year period is reduced in boys with autism spectrum disorder (ASD) compared with typically developing controls. STUDY DESIGN: Twenty-five boys with ASD and 24 controls were assessed for bone outcomes. Fourteen boys with ASD and 11 controls were assessed both at baseline and after 4 years. The mean subject age was 11.0 ± 1.6 years at study initiation and 14.9 ± 1.6 years at follow-up. Bone mineral density (BMD) was measured at the spine, hip, and whole body using dual-energy X-ray absorptiometry and normalized for age, race, and sex (BMD z-scores)...
November 22, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27883987/changes-in-lumbopelvic-rhythm-during-trunk-extension-in-adolescent-soccer-players
#18
Michio Tojima, Suguru Torii
Many adolescent athletes experience low back pain (LBP). Its causative factors include lower limb muscle tightness and hip-spine incoordination. Hip-spine coordination [or lumbopelvic rhythm, LPR] can be used to assess lower-limb and spine functions. We assessed the presence/absence of LBP in adolescent soccer players before and after a six-month period and divided them into four groups: no LBP both before and after the period (NBP group); LBP before but not after (PN group); LBP after but not before (NP group); and LBP both before and after (LBP group)...
November 15, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27881628/normative-reference-values-for-strength-and-flexibility-of-1-000-children-and-adults
#19
Marnee J McKay, Jennifer N Baldwin, Paulo Ferreira, Milena Simic, Natalie Vanicek, Joshua Burns
OBJECTIVE: To establish reference values for isometric strength of 12 muscle groups and flexibility of 13 joint movements in 1,000 children and adults and investigate the influence of demographic and anthropometric factors. METHODS: A standardized reliable protocol of hand-held and fixed dynamometry for isometric strength of ankle, knee, hip, elbow, and shoulder musculature as well as goniometry for flexibility of the ankle, knee, hip, elbow, shoulder, and cervical spine was performed in an observational study investigating 1,000 healthy male and female participants aged 3-101 years...
November 23, 2016: Neurology
https://www.readbyqxmd.com/read/27874298/volitional-spine-stabilization-during-a-drop-vertical-jump-from-different-landing-heights-implications-for-anterior-cruciate-ligament-injury
#20
Ram Haddas, Troy Hooper, C Roger James, Phillip S Sizer
CONTEXT:  Volitional spine stabilization (VSS) during dynamic activities may alter trunk motion, but the role of the core musculature in positioning the trunk during landing tasks is unclear. OBJECTIVE:  To determine whether volitional core-muscle activation incorporated during a drop vertical jump alters lower extremity kinematics and kinetics, as well as trunk and lower extremity muscle activity at different landing heights. DESIGN:  Controlled laboratory study...
November 22, 2016: Journal of Athletic Training
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