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https://www.readbyqxmd.com/read/28453635/peak-bone-mass-and-bone-microarchitecture-in-adults-born-with-low-birth-weight-preterm-or-at-term-a-cohort-study
#1
Chandima Balasuriya, Kari Anne I Evensen, Mats P Mosti, Ann-Mari Brubakk, Geir W Jacobsen, Marit S Indredavik, Berit Schei, Astrid Kamilla Stunes, Unni Syversen
Context and objectives: Peak bone mass (PBM) is regarded as the most important determinant of osteoporosis. Growing evidence suggests a role of intrauterine programming in skeletal development. We examined PBM and trabecular bone score (TBS) in adults born preterm with very low birth weight (VLBW) or small for gestational age (SGA) at term compared with term-born controls. Design, setting, participants and outcomes: This follow-up cohort study included 186 men and women (25-28 years); 52 preterm VLBW (≤ 1500g), 59 term-born SGA (< 10th percentile), and 75 controls (>10th percentile)...
April 27, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28453307/-643c%C3%A2-%C3%A2-t-rankl-gene-polymorphism-is-associated-with-osteoporosis-in-tunisian-postmenopausal-women
#2
R Sassi, H Sahli, E Cheour, S Sellami, A Ben Ammar El Gaaied
OBJECTIVES: The dynamic nature of the skeleton is achieved by a remodeling process. Receptor activator of nuclear factor kappa B (RANK) ligand (RANKL) stimulates bone resorption by activating RANK signaling. Therefore it is considered as a candidate gene regulating susceptibility to osteoporosis. In the current study, we have investigated the association between the RANKL gene -693G > C and -643 C > T polymorphisms and bone mineral density (BMD) in a population of postmenopausal Tunisian women...
April 28, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28445303/lifetime-and-recent-alcohol-use-and-bone-mineral-density-in-adults-with-hiv-infection-and-substance-dependence
#3
Alicia S Ventura, Michael R Winter, Timothy C Heeren, Meg M Sullivan, Alexander Y Walley, Michael F Holick, Gregory J Patts, Seville M Meli, Jeffrey H Samet, Richard Saitz
Low bone mineral density (BMD) is common in people living with HIV infection (PLWH), increasing fracture risk. Alcohol use is also common in PLWH and is a modifiable risk factor for both HIV disease progression and low BMD. In PLWH, alcohol's effect on BMD is not well understood.We studied adult PLWH with substance dependence. We measured lifetime alcohol use (kg) and recent (i.e., past 30-day) alcohol use (categorized as: abstinent, low risk, or high risk). In adjusted multivariable regression analyses, we tested associations between lifetime and recent alcohol use and (i) mean BMD (g/cm) at the femoral neck, total hip, and lumbar spine and (ii) low BMD diagnosis (i...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28444432/childhood-growth-predicts-higher-bone-mass-and-greater-bone-area-in-early-old-age-findings-among-a-subgroup-of-women-from-the-helsinki-birth-cohort-study
#4
T M Mikkola, M B von Bonsdorff, C Osmond, M K Salonen, E Kajantie, C Cooper, M J Välimäki, J G Eriksson
We examined the associations between childhood growth and bone properties among women at early old age. Early growth in height predicted greater bone area and higher bone mineral mass. However, information on growth did not improve prediction of bone properties beyond that predicted by body size at early old age. INTRODUCTION: We examined the associations between body size at birth and childhood growth with bone area, bone mineral content (BMC), and areal bone mineral density (aBMD) in early old age...
April 25, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28442297/vertebral-and-femoral-bone-mineral-density-and-bone-strength-in-prostate-cancer-patients-assessed-in-phantomless-pet-ct-examinations
#5
Benedikt J Schwaiger, David L Kopperdahl, Lorenzo Nardo, Luca Facchetti, Alexandra S Gersing, Jan Neumann, Kwang J Lee, Tony M Keaveny, Thomas M Link
PURPOSE: Bone fracture risk assessed ancillary to positron emission tomography with computed tomography co-registration (PET/CT) could provide substantial clinical value to oncology patients with elevated fracture risk without introducing additional radiation dose. The purpose of our study was to investigate the feasibility of obtaining valid measurements of bone mineral density (BMD) and finite element analysis-derived bone strength of the hip and spine using PET/CT examinations of prostate cancer patients by comparing against values obtained using routine multidetector-row computed tomography (MDCT) scans-as validated in previous studies-as a reference standard...
April 22, 2017: Bone
https://www.readbyqxmd.com/read/28438449/ankylosing-spondylitis-increases-perioperative-and-postoperative-complications-after-total-hip-arthroplasty
#6
Daniel J Blizzard, Colin T Penrose, Charles Z Sheets, Thorsten M Seyler, Michael P Bolognesi, Christopher R Brown
BACKGROUND: Ankylosing spondylitis (AS) is a chronic autoimmune spondyloarthropathy that primarily affects the axial spine and hips. Progressive disease leads to pronounced spinal kyphosis, positive sagittal balance, and altered biomechanics. The purpose of this study is to determine the complication profile of patients with AS undergoing total hip arthroplasty (THA). METHODS: The Medicare sample was searched from 2005 to 2012 yielding 1006 patients with AS who subsequently underwent THA...
March 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28438150/intermittent-parathyroid-hormone-improve-bone-microarchitecture-of-the-mandible-and-femoral-head-in-ovariectomized-rats
#7
Ying-Ju Chen, Shun-Ping Wang, Fu-Chou Cheng, Pei-Yu Hsu, Yu-Fen Li, Jay Wu, Heng-Li Huang, Ming-Tzu Tsai, Jui-Ting Hsu
BACKGROUND: Intermittent parathyroid hormone (PTH) can be used to treat osteoporosis of the spine and hip. However, whether it can be used to treat osteoporosis of the mandible is unclear. The purpose of this study was to explore the influence of applying intermittent PTH to ovariectomized rats on the trabecular bone microarchitecture of the mandible and femoral head. METHODS: Eighteen female rats were divided into three groups: the healthy group, ovariectomized (OVX) group, and OVX + PTH group...
April 24, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28437548/arthroscopic-treatment-of-a-displaced-nonunion-of-the-anterior-inferior-iliac-spine-causing-extra-articular-impingement
#8
Motoi Shibahara, Yasuo Ohnishi, Eisaburo Honda, Dean K Matsuda, Soshi Uchida
This report describes a case of nonunion of an anterior inferior iliac spine (AIIS) apophyseal avulsion fracture with resultant subspine impingement combined with symptomatic femoroacetabular impingement (FAI). A 16-year-old male soccer player presented with a 6-month history of right groin pain exacerbated by kicking and running. The patient was diagnosed with a displaced nonunion of the AIIS apophysis avulsion fracture causing secondary extra-articular impingement beyond cam-type FAI by physical examination and radiological findings...
April 24, 2017: Orthopedics
https://www.readbyqxmd.com/read/28437347/effect-of-coronal-scoliotic-curvature-on-sagittal-spinal-shape-analysis-of-parameters-in-mature-adolescent-scoliosis-patients
#9
Jae-Young Hong, Keon-Woo Kim, Seung-Woo Suh, Si-Young Park, Jae-Hyuk Yang
STUDY DESIGN: A radiographic analysis with scoliosis patients. OBJECTIVES: To analyze correlations between sagittal spinal alignment and coronal scoliotic curvature. SUMMARY OF BACKGROUND DATA: Sagittal spinal alignment and scoliosis may have a significant relationship, and schematic analysis is needed. METHODS: The study group was comprised of 163 patients with adolescent idiopathic scoliosis. Subjects underwent anteroposterior and lateral radiographs of the whole spine including hip joints...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28437346/correlations-between-sagittal-spinal-balance-and-quality-of-life-in-rheumatoid-arthritis
#10
Hong Seok Lee, Jung Sub Lee, Jong Ki Shin, Tae Sik Goh
STUDY DESIGN: Prospective study. OBJECTIVE: To identify relationships between spinopelvic parameters and health-related quality of life in rheumatoid arthritis (RA). SUMMARY OF BACKGROUND DATA: Little data are available on relationships between sagittal spinopelvic parameters and health-related quality of life in RA. MATERIALS AND METHODS: The study and control groups comprised 120 RA patients and 60 controls. All subjects underwent anteroposterior and lateral radiography of the whole spine, including hip joints, and all completed clinical questionnaires...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28437220/lean-mass-and-fat-mass-as-mediators-of-the-relationship-between-physical-activity-and-bone-mineral-density-in-postmenopausal-women
#11
Jing Xiang, Yongjie Chen, Yupeng Wang, Shaofei Su, Xinyu Wang, Biao Xie, Qiuju Zhang, Meina Liu
BACKGROUND: The relationship between physical activity (PA) and bone health is well known, but the role of lean mass (LM) and fat mass (FM) in this relationship remains uncertain. Therefore, the aim of this study was to examine the mediating effect of LM and FM on the relationship between PA and bone mineral density (BMD) in postmenopausal women. MATERIALS AND METHODS: This cross-sectional study involved 282 postmenopausal women aged between 50 and 65 year, who were randomly selected from Hongqi community of Harbin City in China...
February 28, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28436196/bone-mineral-density-and-fractures-after-surgical-menopause-a-systematic-review-and-meta-analysis
#12
Ingrid E Fakkert, Natalia Teixeira, Elske Marije Abma, Riemer H J A Slart, Marian J E Mourits, Geertruida H de Bock
BACKGROUND: Oophorectomy is recommended to women at increased ovarian cancer risk. When performed at premenopausal age oophorectomy induces acute surgical menopause, with unwanted consequences. OBJECTIVE: To investigate bone mineral density (BMD) and fracture prevalence after surgical menopause. SEARCH STRATEGY: A literature search on PubMed, Embase and Cochrane library through March 2016. SELECTION CRITERIA: Primary studies reporting on BMD, T-scores or fracture prevalence in women with surgical menopause and age-matched reference groups...
April 24, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28435744/diagnosis-of-spinal-epidural-abscess-a-case-report-and-literature-review
#13
Chidinma Chima-Melton, Michelle Pearl, Marni Scheiner
INTRODUCTION: Spinal epidural abscess (SEA) is a rare but serious cause of back pain in the critical care setting. It occurs most commonly in adults in their fifth and sixth decades of life. Risk factors include diabetes mellitus, alcoholism, AIDS or other immunocompromised states, cancer, intravenous drug use, trauma and spinal surgery. The clinical presentation can be non-specific but the classical triad includes back pain, fever and neurological deficits. Magnetic resonance imaging (MRI) with gadolinium is the diagnostic imaging modality of choice...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28432458/is-the-evaluation-of-the-anterior-inferior-iliac-spine-aiis-in-the-ap-pelvis-possible-analysis-of-conventional-x-rays-and-3d-ct-reconstructions
#14
David R Krueger, Markus Windler, Markus Geßlein, Michael Schuetz, Carsten Perka, Joerg H Schroeder
INTRODUCTION: A hypertrophic AIIS has been identified as a cause for extraarticular hip impingement and is classified according to Hetsroni using 3D-CT reconstructions. The role of the conventional AP pelvis X-ray, which is the first standard imaging step for the evaluation of hip pain, has not been investigated yet. MATERIALS AND METHODS: AP pelvis X-rays and 3D-CT reconstructions of patients were evaluated regarding their morphology of the AIIS. The conventional X-rays were categorized into three groups according to the projection of the AIIS: above (A) or below (B) the acetabular sourcil or even exceeding the anterior acetabular rim (C)...
April 21, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28427725/association-of-mild-leg-length-discrepancy-and-degenerative-changes-in-the-hip-joint-and-lumbar-spine
#15
Kelvin J Murray, Tom Molyneux, Michael R Le Grande, Aurora Castro Mendez, Franz K Fuss, Michael F Azari
OBJECTIVE: The purpose of this study was to evaluate the correlation between mild leg length discrepancy (LLD) and degenerative joint disease (DJD) or osteoarthritis. METHODS: We evaluated standard postural lumbopelvic radiographs from 255 adults (121 women and 134 men) who had presented with spinal pain for chiropractic care. Symmetry of femoral head diameters was used to exclude magnification errors. Pearson's partial correlation was used to control for age and derive effect sizes for LLD on DJD in the hip and lower lumbar motion segments...
April 17, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28425086/the-clinical-benefits-of-denosumab-for-prophylaxis-of-steroid-induced-osteoporosis-in-patients-with-pulmonary-disease
#16
Shigeo Ishiguro, Kentaro Ito, Shigenori Nakagawa, Osamu Hataji, Akihiro Sudo
Previous reports demonstrated that bone density decreased rapidly during the initial few months of steroid therapy and continued decreasing at a rate of 2 to 4% annually. Our data indicates that denosumab can also play a role in the treatment of osteoporosis in the steroid-taking population. INTRODUCTION: Respiratory physicians are often faced with the dilemma that long-term steroid use will deteriorate bone mineral density and quality. Previous reports demonstrated that bone density decreased 8 to 12% during the initial few months of steroid therapy then continued decreasing at a rate of 2 to 4% annually...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28423434/-radiologic-presentation-in-subspine-impingement-and-correlation-with-intraarticular-impingement-in-the-hip
#17
David R Krüger, Michael Schütz, Carsten Perka, Jörg Schröder
Background Besides the known intraarticular femoroacetabular impingement (FAI), recently forms of extra-articular impingement of the hip have been increasingly recognized. Recent studies have described an extra-articular impingement between a distal extension of the anterior inferior iliac spine (AIIS) and the femoral neck (AIIS or subspine impingement). Evidently, an association between this subspine impingement and an intraarticular FAI seems to exist. Little is known about the incidence of this impingement type and the value of its radiological diagnostics...
April 19, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28415980/the-effects-of-bending-speed-on-the-lumbo-pelvic-kinematics-and-movement-pattern-during-forward-bending-in-people-with-and-without-low-back-pain
#18
Sharon M H Tsang, Grace P Y Szeto, Linda M K Li, Dim C M Wong, Millie M P Yip, Raymond Y W Lee
BACKGROUND: Impaired lumbo-pelvic movement in people with low back pain during bending task has been reported previously. However, the regional mobility and the pattern of the lumbo-pelvic movement were found to vary across studies. The inconsistency of the findings may partly be related to variations in the speed at which the task was executed. This study examined the effects of bending speeds on the kinematics and the coordination lumbo-pelvic movement during forward bending, and to compare the performance of individuals with and without low back pain...
April 17, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28411742/a-biomechanical-and-physiological-study-of-office-seat-and-tablet-device-interaction
#19
Eric Weston, Peter Le, William S Marras
Twenty subjects performed typing tasks on a desktop computer and touch-screen tablet in two chairs for an hour each, and the effects of chair, device, and their interactions on each dependent measure were recorded. Biomechanical measures of muscle force, spinal load, and posture were examined, while discomfort was measured via heart rate variability (HRV) and subjective reports. HRV was sensitive enough to differentiate between chair and device interactions. Biomechanically, a lack of seat back mobility forced individuals to maintain an upright seating posture with increased extensor muscle forces and increased spinal compression...
July 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28408276/low-serum-concentrations-of-irisin-are-associated-with-increased-risk-of-hip-fracture-in-chinese-older-women
#20
Jun Yan, Hai-Juan Liu, Wei-Chun Guo, Jian Yang
OBJECTIVE: Irisin derived from muscle in response to exercise may be the molecular entity responsible for muscle wasting-osteoporosis connectivity in the elderly. The objective of the study was to determine whether serum Irisin (sIrisin) provides information on hip fracture prediction which were independent of bone mineral density (BMD) and the fracture risk assessment tool (FRAX) algorithm. METHODS: This study enrolled 160 older women (ages, 70-90 y) with minimal trauma hip fractures (MTHFs) and 160 age-matched women without fracture serving as controls...
April 10, 2017: Joint, Bone, Spine: Revue du Rhumatisme
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