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https://www.readbyqxmd.com/read/28097915/the-relationship-between-angiotensin-converting-enzyme-ace-insertion-i-deletion-d-polymorphism-serum-ace-activity-and-bone-mineral-density-bmd-in-older-chinese
#1
Ya-Feng Zhang, Hong Wang, Qiong Cheng, Ling Qin, Nelson Ls Tang, Ping-Chong Leung, Timothy Cy Kwok
OBJECTIVE: In this study, we set out to investigate the relationship between angiotensin-converting enzyme ( ACE) I/D polymorphism, serum ACE activity and bone mineral density (BMD) in older Chinese. METHODS: A standardized, structured, face-to-face interview was performed to collect demographic information. BMD was measured using dual-energy X-ray absorptiometry (DXA). I/D genotypes of ACE were determined by polymerase chain reaction (PCR) amplification. Serum ACE activity was determined photometrically by a commercially available kinetic kit...
January 2017: Journal of the Renin-angiotensin-aldosterone System: JRAAS
https://www.readbyqxmd.com/read/28097253/practical-implications-of-the-lumbar-spine-and-its-function-on-total-hip-arthroplasty
#2
EDITORIAL
Vincent Vinh Gia An, Brahman Shankar Sivakumar, Yadin David Levy, Jim Pierrepont, Warwick James Bruce
Correct component placement is of significant importance to ensure optimal outcomes in total hip arthroplasty (THA). Traditionally, the Lewinnek plane has been referenced as an adequate "safe zone", formed between the anterior superior iliac spines and public tubercles to optimize acetabular orientation. However, recent evidence shows that the positioning of this plane may vary due to the biomechanical relationship between the lumbar spine and hip. Therefore, the plane acquired intraoperatively may not accurately recreate the actual functional plane and acetabular orientation encountered outside of the intraoperative environment...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28097242/anterior-to-psoas-atp-fusion-of-the-lumbar-spine-evolution-of-a-technique-facilitated-by-changes-in-equipment
#3
Cristian Gragnaniello, Kevin Seex
BACKGROUND: Lateral interbody cages have been proven useful in spinal fusions. Spanning both lateral cortical rims while sparing the Anterior Longitudinal Ligament, the lateral interbody cages restore and maintain disc height while adding stability prior to supplemental fixation. The standard approach for their insertion is by a 90-degree lateral transpsoas method. This is relatively bloodless compared to other techniques although has its limitations, requiring neuro-monitoring and being, at times, very difficult at L4/5 due to iliac crest obstruction or an anterior plexus position...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28096639/association-between-serum-25-hydroxyvitamin-d-levels-and-bone-mineral-density-in-normal-postmenopausal-women
#4
Vasundhara Kamineni, Akkenapally Prasanna Latha, K Ramathulasi
AIM: This study was conducted with the objective of assessing serum 25-hydroxyvitamin D (25(OH)D) in postmenopausal women (PMW), to detect osteopenia or osteoporosis in PMW and to establish a correlation between serum 25(OH)D levels and bone mineral density (BMD). MATERIALS AND METHODS: A total of 100 healthy PMW were selected, and a prospective observational study was conducted to correlate the BMD with serum 25(OH)D levels. Their laboratory investigations along with serum 25(OH)D levels were done...
October 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28093633/dietary-potassium-intake-is-beneficial-to-bone-health-in-a-low-calcium-intake-population-the-korean-national-health-and-nutrition-examination-survey-knhanes-2008-2011
#5
S H Kong, J H Kim, A R Hong, J H Lee, S W Kim, C S Shin
: Dietary potassium may neutralize acid load and reduce calcium loss from the bone, leading to beneficial effect on bone mineral density. In this nationwide Korean population study, dietary potassium intake was associated with improved bone mineral density in older men and postmenopausal women. INTRODUCTION: Nutrition is a major modifiable factor that affects bone health. The accompanying anion in dietary potassium may act as an alkaline source by neutralizing the acid load and reducing calcium loss from the bone...
January 16, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28088646/bone-microarchitecture-in-adolescent-boys-with-autism-spectrum-disorder
#6
Ann M Neumeyer, Natalia Cano Sokoloff, Erin McDonnell, Eric A Macklin, Christopher J McDougle, Madhusmita Misra
BACKGROUND: Boys with autism spectrum disorder (ASD) have lower areal bone mineral density (aBMD) than typically developing controls (TDC). Studies of volumetric BMD (vBMD) and bone microarchitecture provide information about fracture risk beyond that provided by aBMD but are currently lacking in ASD. OBJECTIVES: To assess ultradistal radius and distal tibia vBMD, bone microarchitecture and strength estimates in adolescent boys with ASD compared to TDC. DESIGN/METHODS: Cross-sectional study of 34 boys (16 ASD, 18 TDC) that assessed (i) aBMD at the whole body (WB), WB less head (WBLH), hip and spine using dual X-ray absorptiometry (DXA), (ii) vBMD and bone microarchitecture at the ultradistal radius and distal tibia using high-resolution peripheral quantitative CT (HRpQCT), and (iii) bone strength estimates (stiffness and failure load) using micro-finite element analysis (FEA)...
January 11, 2017: Bone
https://www.readbyqxmd.com/read/28077016/bone-mineral-density-is-close-to-normal-for-age-in-long-term-lymphoma-survivors-treated-with-high-dose-therapy-with-autologous-stem-cell-transplantation
#7
Mette Seland, Knut B Smeland, Trine Bjøro, Ragnhild S Falk, Sophie D Fosså, Clara G Gjesdal, Kristin Godang, Harald Holte, Johan Svartberg, Unni Syversen, Jens Bollerslev, Cecilie E Kiserud
BACKGROUND: Few studies have assessed bone health in lymphoma survivors treated with high-dose therapy with autologous stem cell transplantation (HDT-ASCT). Therefore, we aimed to assess bone mineral density (BMD) at six different skeletal sites and to investigate associations between clinical factors and BMD in these survivors. MATERIAL AND METHODS: Eligible lymphoma survivors were aged ≥18 years at diagnosis and at HDT-ASCT given between 1987 and 2008. Participants responded to questionnaires, blood samples were drawn, and a dual energy X-ray absorptiometry (DXA) was performed...
January 12, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28071822/responses-to-treatment-with-teriparatide-in-patients-with-atypical-femur-fractures-previously-treated-with-bisphosphonates
#8
Nelson B Watts, Deborah Aggers, Edward F McCarthy, Tina Savage, Stephanie Martinez, Rachel Patterson, Erin Carrithers, Paul D Miller
If over-suppression of bone turnover explained the association between bisphosphonate use and atypical subtrochanteric femur fractures (AFF), this could be reversed with anabolic treatment such as teriparatide. We conducted a prospective, open label study in patients previously treated with bisphosphonates who sustained AFF, examining the response to 24 months treatment with teriparatide on bone mineral density (BMD), trabecular bone score (TBS), bone turnover markers (BTM) and fracture healing as well as quantitative histomorphometry...
January 10, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28066737/anterior-inferior-iliac-spine-aiis-and-subspine-hip-impingement
#9
Patrick Carton, David Filan
BACKGROUND: Abnormal morphology of the anterior inferior iliac spine (AIIS) and the subspine region of the acetabular rim are increasingly being recognised as a source of symptomatic extra-articular hip impingement. This review article aims to highlight important differences in the pathogenesis, clinical presentation and management of extra-articular hip impingement from both the AIIS and subspine bony regions, and the outcome following surgical intervention. METHODS: A literature review was undertaken to examine the supporting evidence for AIIS and subspine hip impingement...
July 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/28064540/romosozumab-for-the-treatment-of-osteoporosis
#10
Leonardo Bandeira, E Michael Lewiecki, John P Bilezikian
Introduction Sclerostin, a glycoprotein produced primarily by osteocytes, blocks the canonical Wnt signaling bone formation pathway. Romosozumab is a humanized monoclonal antibody to sclerostin that binds to sclerostin, permitting the engagement of Wnt ligands with their co-receptors, resulting in an increase in bone formation and bone mineral density (BMD). Clinical studies with romosozumab have shown dramatic improvements in BMD at the spine and hip. Romosozumab is associated with improvement in bone strength through mechanisms that include increases in bone formation and, different from classical osteoanabolic agents, suppression of bone resorption...
January 9, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28060533/morphological-distribution-of-the-anterior-inferior-iliac-spine-in-patients-with-and-without-hip-impingement
#11
George C Balazs, Benjamin C Williams, Christopher M Knaus, Daniel I Brooks, Jonathan F Dickens, Michael P McCabe, Terrence D Anderson
BACKGROUND: Subspinous impingement of the anterior inferior iliac spine (AIIS) on the femoral head-neck junction is increasingly recognized as a source of hip impingement. A classification system of AIIS morphology has previously been proposed that correlates with reduced hip motion and may predispose patients to subspinous hip impingement. PURPOSE: To examine the morphological distribution of AIIS types in patients with and without diagnosed hip impingement and correlate AIIS morphology to intraoperative findings at the time of surgery...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28057200/epidemiology-and-recent-trends-of-geriatric-fractures-presenting-to-the-emergency-department-for-united-states-population-from-year-2004-2014
#12
N K Baidwan, S M Naranje
OBJECTIVES: Fractures in geriatric age group (over 65 years of age) are an important public health issue and frequent causes of emergency room visits. The purpose of this descriptive epidemiological study was to present the epidemiology of geriatric fractures and their trends in the USA using National Electronic Injury Surveillance System (NEISS) database from year 2004-2014. METHODS: National Electronic Injury Surveillance System (NEISS) Database was queried for all fracture injuries from 2004 to 2014 for ages 65 years and above...
January 2017: Public Health
https://www.readbyqxmd.com/read/28056455/the-association-of-musculoskeletal-pain-with-bone-mineral-density-in-patients-with-parkinson-s-disease
#13
Seong-Min Choi, Byeong C Kim, Hyun-Jung Jung, Geum-Jin Yoon, Kyung Wook Kang, Kang-Ho Choi, Seung-Han Lee, Man-Seok Park, Myeong-Kyu Kim, Ki-Hyun Cho
BACKGROUND: Pain and osteoporosis are common in Parkinson's disease (PD), and lower bone mineral density (BMD) or osteoporosis may be associated with an increased risk of reporting to have pain in the general population. The aim of this study was to determine whether there is an association between the pain subtypes and the BMD in patients with PD. METHODS: We included 162 PD patients. Pain was assessed using the patients' descriptions, a structured interview, a detailed neurologic examination, and the Visual Analogue Scale...
January 5, 2017: European Neurology
https://www.readbyqxmd.com/read/28050925/bone-mineral-density-balance-performance-balance-self-efficacy-and-falls-in-breast-cancer-survivors-with-and-without-qigong-training
#14
Shirley S M Fong, Anna W M Choi, W S Luk, Timothy T T Yam, Joyce C Y Leung, Joanne W Y Chung
PURPOSE: A deterioration in bone strength and balance performance after breast cancer treatment can result in injurious falls. Therefore, interventions need to be developed to improve the bone strength and balance ability of breast cancer survivors. This cross-sectional exploratory study aimed to compare the bone mineral density (BMD), balance performance, balance self-efficacy, and number of falls between breast cancer survivors who practiced qigong, breast cancer survivors who did not practice qigong, and healthy individuals...
December 1, 2016: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28050814/what-orthopaedic-operating-room-surfaces-are-contaminated-with-bioburden-a-study-using-the-atp-bioluminescence-assay
#15
Raveesh Daniel Richard, Thomas R Bowen
BACKGROUND: Contaminated operating room surfaces can increase the risk of orthopaedic infections, particularly after procedures in which hardware implantation and instrumentation are used. The question arises as to how surgeons can measure surface cleanliness to detect increased levels of bioburden. This study aims to highlight the utility of adenosine triphosphate (ATP) bioluminescence technology as a novel technique in detecting the degree of contamination within the sterile operating room environment...
January 3, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28049594/anterior-inferior-iliac-spine-morphology-and-outcomes-of-hip-arthroscopy-in-soccer-athletes-a%C3%A2-comparison-to-nonkicking-athletes
#16
Danyal H Nawabi, Ryan M Degen, Kara G Fields, Catherine S Wentzel, Olusanjo Adeoye, Bryan T Kelly
PURPOSE: To describe the anterior inferior iliac spine (AIIS) morphology and clinical outcomes following arthroscopic surgical decompression in a group of high-level soccer athletes presenting with symptomatic hip impingement when compared with a control group of nonkicking athletes. METHODS: From 2009 to 2012, we retrospectively reviewed our prospective hip registry for soccer athletes who underwent arthroscopic treatment for femoroacetabular impingement (FAI) with 2-year follow-up, comparing with a control group of nonkicking athletes...
December 31, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28049234/chronic-kidney-disease-mineral-bone-disorder-in-korean-patients-a-report-from-the-korean-cohort-study-for-outcomes-in-patients-with-chronic-kidney-disease-know-ckd
#17
Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Seung Hyeok Han, Kyu Beck Lee, Joongyub Lee, Kook Hwan Oh, Dong Wan Chae, Soo Wan Kim
This study examined the characteristics of biochemical parameters, bone diseases, and vascular calcification in Korean patients with chronic kidney disease (CKD) not yet on dialysis. Serum levels of fibroblast growth factor 23 (FGF23), intact parathyroid hormone (iPTH), 25-hydroxyvitamin D3 (25D), and 1,25-dihydroxyvitamin D3 (1,25D); lumbar spine, total hip, and femur neck bone mineral densities; and brachial-to-ankle pulse wave velocity (baPWV) representing vascular calcification were measured at baseline for 2,238 CKD patients in the KoreaN Cohort Study for Outcomes in Patients With CKD (KNOW-CKD)...
February 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28046251/su-g-iep3-02-characteristics-of-in-vivo-mosfet-dosimeters-for-diagnostic-x-ray-low-dose-measurements
#18
S Li, S Ali, K Harper, Q Liang, D Serratore
PURPOSE: To correct in-vivo metal-oxide-semiconductor field-effect transistor (MOSFET) dosimeters dependence on X-ray energy, dose and dose rate, and temperature in order to measure doses or exposures on several anatomic points of interest undergoing some routine radiographs. METHODS: A mobile MOSFET system (BEST Medical) was carefully calibrated with X-ray at kVp of 70, 80, 100, 120, and 138 kVp, phantom temperatures at 0, 21, and 43 oC, and exposure range from 0...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045945/greater-intake-of-fruit-and-vegetables-is-associated-with-greater-bone-mineral-density-and-lower-osteoporosis-risk-in-middle-aged-and-elderly-adults
#19
Rui Qiu, Wen-Ting Cao, Hui-Yuan Tian, Juan He, Geng-Dong Chen, Yu-Ming Chen
OBJECTIVE: A few studies have suggested that the consumption of fruit and vegetables (FV) may benefit bone health, but limited data are available in Asian subjects. We examined the association between FV intake and bone mineral density (BMD) and osteoporosis in Chinese adults. METHODS: This population-based cross-sectional study involved 2083 women and 1006 men aged 40-75 years in Guangzhou, China. Habitual dietary data was collected from a 79-item food frequency questionnaire by face-to-face interviews...
2017: PloS One
https://www.readbyqxmd.com/read/28045713/differentiating-hip-pathology-from-lumbar-spine-pathology-key-points-of-evaluation-and-management
#20
Aaron J Buckland, Ryan Miyamoto, Rakesh D Patel, James Slover, Afshin E Razi
The diagnosis and treatment of patients who have both hip and lumbar spine pathologies may be a challenge because overlapping symptoms may delay a correct diagnosis and appropriate treatment. Common complaints of patients who have both hip and lumbar spine pathologies include low back pain with associated buttock, groin, thigh, and, possibly, knee pain. A thorough patient history should be obtained and a complete physical examination should be performed in these patients to identify the primary source of pain...
December 29, 2016: Journal of the American Academy of Orthopaedic Surgeons
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