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https://www.readbyqxmd.com/read/28523210/care-pathway-for-cancer-survivorship-in-korea-trend-of-breast-cancer-pathway-from-2003-to-2010
#1
Hwa Jeong Seo, Dong Yong Noh
OBJECTIVES: The survival rate of cancer patients has exceeded 60%. Although cancer survivors may die of other diseases except cancer, the health management system including chronic disease prevention-management for cancer survivors, has not been established in the diverse aspects. Therefore, services according to care pathway of cancer patients need to be provided through a support system based on a platform concept that can be used to meet patient needs in various ways. METHODS: A sample cohort database (2002-2010) of approximately 1 million persons-2% of the whole nation (50 million)-was used to estimate cancer survivors through a principal care pathway for cancer management...
April 2017: Healthcare Informatics Research
https://www.readbyqxmd.com/read/28520780/towards-a-point-of-care-strip-test-to-diagnose-sickle-cell-anemia
#2
Meaghan Bond, Brady Hunt, Bailey Flynn, Petri Huhtinen, Russell Ware, Rebecca Richards-Kortum
A rapid test to identify patients with sickle cell disease could have important benefits in low-resource settings. Sickle cell anemia (SCA) affects about 300,000 newborns each year, the majority of whom are born in sub-Saharan Africa. Low-cost therapies are available to treat SCA, but most countries in sub-Saharan Africa lack robust neonatal screening programs needed to identify patients in need of treatment. To address this need, we developed and evaluated a competitive lateral flow assay that identifies patients with SCA (genotype HbSS) in 15 minutes using undiluted whole blood...
2017: PloS One
https://www.readbyqxmd.com/read/28501225/introduction-to-integrative-medicine-in-the-primary-care-setting
#3
REVIEW
Melinda Ring, Rupa Mahadevan
Integrative Medicine has been described as "healing oriented medicine that takes account of the whole person (body, mind, and spirit) including all aspects of lifestyle. It emphasizes therapeutic relationships and makes use of all appropriate therapies, both conventional and alternative." National surveys consistently report that approximately one-third of adults and 12% of children use complementary and integrative medicine approaches. Although there are barriers to primary care professionals engaging in discussions about lifestyle change and complementary and integrative medicine options, there is also great potential to impact patient well-being...
June 2017: Primary Care
https://www.readbyqxmd.com/read/28493140/-health-disorders-and-their-prevalence-in-two-primary-care-practices-from-the-perspective-of-different-coding
#4
Waltraud Fink, Otto Kasper, Gustav Kamenski
Family practices provide medical care for the majority of health problems. This already highlights the importance of primary health care with respect to quantity. A detailed five-year survey of cases in two rural practices gives insight into everyday practice. During the whole period of this year's prevalence survey, 24,541 or 32,605 episodes of care were recorded in a mean practice population of 1500 or 1700 persons, respectively. The frequency rates of more than 500 different health problems show a typical Pareto distribution...
May 10, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28486495/long-term-inpatient-disease-burden-in-the-adult-life-after-childhood-cancer-in-scandinavia-aliccs-study-a-cohort-study-of-21-297-childhood-cancer-survivors
#5
Sofie de Fine Licht, Kathrine Rugbjerg, Thorgerdur Gudmundsdottir, Trine G Bonnesen, Peter Haubjerg Asdahl, Anna Sällfors Holmqvist, Laura Madanat-Harjuoja, Laufey Tryggvadottir, Finn Wesenberg, Henrik Hasle, Jeanette F Winther, Jørgen H Olsen
BACKGROUND: Survivors of childhood cancer are at increased risk for a wide range of late effects. However, no large population-based studies have included the whole range of somatic diagnoses including subgroup diagnoses and all main types of childhood cancers. Therefore, we aimed to provide the most detailed overview of the long-term risk of hospitalisation in survivors of childhood cancer. METHODS AND FINDINGS: From the national cancer registers of Denmark, Finland, Iceland, and Sweden, we identified 21,297 5-year survivors of childhood cancer diagnosed with cancer before the age of 20 years in the periods 1943-2008 in Denmark, 1971-2008 in Finland, 1955-2008 in Iceland, and 1958-2008 in Sweden...
May 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28439713/personalized-axillary-dissection-the-number-of-excised-lymph-nodes-of-nodal-positive-breast-cancer-patients-has-no-significant-impact-on-relapse-free-and-overall-survival
#6
Florian Ebner, Achim Wöckel, Wolfgang Janni, Rolf Kreienberg, Lukas Schwentner, Manfred Wischnewsky
PURPOSE: Sentinel lymph node (SLN) biopsy has replaced axillary lymph node dissection (ALND) for the staging of clinically node-negative breast cancer patients (BCP), demonstrating equivalent survival to ALND while resulting in reduced morbidity. ALND has remained the standard of care for the majority of BCP with clinical axillary metastases or metastases found on SLN biopsy. More recently, it is debated whether ALND could be avoided not only in SLN-negative BCP but also in selected SLN-positive disease or even in all patients...
April 24, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28438160/use-of-oral-health-care-services-in-finnish-adults-results-from-the-cross-sectional-health-2000-and-2011-surveys
#7
Anna L Suominen, Sari Helminen, Satu Lahti, Miira M Vehkalahti, Matti Knuuttila, Sinikka Varsio, Anne Nordblad
BACKGROUND: During the 2000s, two major legislative reforms concerning oral health care have been implemented in Finland. One entitled the whole population to subsidized care and the other regulated the timeframes of access to care. Our aim was, in a cross-sectional setting, to assess changes in and determinants of use of oral health care services before the first reform in 2000 and after both reforms in 2011. METHODS: The data were part of the nationally representative Health 2000 and 2011 Surveys of adults aged ≥ 30 years and were gathered by interviews and questionnaires...
April 24, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28423918/expanding-the-palliative-care-domains-to-meet-the-needs-of-a-community-based-supportive-care-model
#8
Eric W Anderson, Monica S Frazer, Sandra E Schellinger
BACKGROUND: Whole person care is appropriate for seriously ill persons. The current framework of palliative care domains in the National Consensus Project (NCP) Guidelines for Quality Palliative Care offers an opportunity to reassess the domains of care delivered at home, earlier in the course of illness. OBJECTIVE: This qualitative study was used to test the applicability of a proposed, expanded set of domains. The results were used to inform a home-based, upstream model of supportive care for serious illness...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28412404/development-of-human-biotransformation-qsars-and-application-for-pbt-assessment-refinement
#9
Ester Papa, Alessandro Sangion, Jon A Arnot, Paola Gramatica
Toxicokinetics heavily influence chemical toxicity as the result of Absorption, Distribution, Metabolism (Biotransformation) and Elimination (ADME) processes. Biotransformation (metabolism) reactions can lead to detoxification or, in some cases, bioactivation of parent compounds to more toxic chemicals. Moreover, biotransformation has been recognized as a key process determining chemical half-life in an organism and is thus a key determinant for bioaccumulation assessment for many chemicals. This study addresses the development of QSAR models for the prediction of in vivo whole body human biotransformation (metabolism) half-lives measured or empirically-derived for over 1000 chemicals, mainly represented by pharmaceuticals...
April 13, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28409741/impact-of-comorbidities-among-medicaid-enrollees-with-chronic-obstructive-pulmonary-disease-united-states-2009
#10
Gloria Westney, Marilyn G Foreman, Junjun Xu, Marshaleen Henriques King, Eric Flenaugh, George Rust
INTRODUCTION: Multimorbidity, the presence of 2 or more chronic conditions, frequently affects people with chronic obstructive pulmonary disease (COPD). Many have high-cost, highly complex conditions that have a substantial impact on state Medicaid programs. We quantified the cost of Medicaid-insured patients with COPD co-diagnosed with other chronic disorders. METHODS: We used nationally representative Medicaid claims data to analyze the impact of comorbidities (other chronic conditions) on the disease burden, emergency department (ED) use, hospitalizations, and total health care costs among 291,978 adult COPD patients...
April 13, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28398144/social-workers-experiences-as-the-family-support-person-during-cardiopulmonary-resuscitation-attempts
#11
Janice Firn, Keli DeVries, Dawnielle Morano, Toni Spano-English
During inhospital cardiopulmonary resuscitation attempts, a designated family support person (FSP) may provide guidance and support to family members. Research on nurses and chaplains in this role has been published. Social workers also regularly fulfill this service, however, little is known about how they perceive and enact this role. To explore their experiences, qualitative interviews (n = 10) were conducted with FSP social workers. Critical realist thematic analysis identified five themes: walking in cold, promoting family presence, responding to the whole spectrum of grief, going beyond the family support role, and repercussions of bearing witness...
April 11, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28393416/psychometric-testing-of-the-slovenian-person-centred-climate-questionnaire-staff-version
#12
Dominika Vrbnjak, Dušica Pahor, Petra Povalej Bržan, David Edvardsson, Majda Pajnkihar
AIM: To test the psychometric properties of the Slovenian version of the Person-centred Climate Questionnaire - staff version. BACKGROUND: Person-centredness can be a quality care indicator, but there are no valid and reliable instruments in the Slovene language aimed at exploring the person-centred care climate from a nursing staff perspective. METHODS: Content validity based on expert agreement was evaluated by calculating content validity indices...
April 10, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28384006/the-effect-of-a-mind-body-intervention-on-mental-health-and-coping-self-efficacy-in-hiv-infected-individuals-a-feasibility-study
#13
Lotte Oerneborg Rodkjaer, Tinne Laursen, Kirsten Seeberg, Marc Drouin, Heinrich Johansen, Charlotte Dyrehave, Bo Langhoff Hønge, Lars Ostergaard
OBJECTIVES: Human immunodeficiency virus (HIV) infection is a stressful disease, and depression is the most common form of psychologic distress experienced by those infected. The aim of this study was to further develop and validate a mind-body intervention to improve coping self-efficacy strategies and increase mental health. DESIGN: Feasibility study, a randomized trial. Participants were assigned into two blocks (female/male) and simple randomization in a 1:1 ratio was performed within each block to one of two arms (1) intervention group, (2) control group who received usual care...
May 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28369028/the-human-side-of-care-coordination-a-whole-person-approach
#14
Charlotte Sortedahl
No abstract text is available yet for this article.
May 2017: Professional Case Management
https://www.readbyqxmd.com/read/28353007/clarifying-values-and-preferences-for-care-near-the-end-of-life-the-role-of-a-new-lay-workforce
#15
Debra K Litzelman, Thomas S Inui, Kathleen M Schmitt-Wendholt, Anthony Perkins, Wilma J Griffin, Ann H Cottingham, Steven S Ivy
Community health workers (CHWs) can engage elderly persons in advance care planning (ACP) conversations. We report how trained CHWs used Go Wish cards (GW (R) cards) to identify patients' highest priority preferences and evaluated whether engaging in ACP conversations was associated with subsequent health care utilization. A one-year long, pre-post longitudinal design was used to evaluate our educational intervention using mixed-methods. 392 patients (mean of 73.3 years, 82% women, 48% African American, 43% Caucasian) enrolled in the Aging Brain Care (ABC) program and participated in ACP discussions with CHWs...
March 28, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28348911/a-case-of-persistent-generalized-retrograde-autobiographical-amnesia-subsequent-to-the-great-east-japan-earthquake-in-2011
#16
Yuji Odagaki
Functional retrograde autobiographical amnesia is often associated with physical and/or psychological trauma. On 11 March 2011, the largest earthquake on record in Japan took place, and subsequent huge tsunami devastated the Pacific coast of northern Japan. This case report describes a patient suffering from retrograde episodic-autobiographical amnesia for whole life, persisting for even more than five years after the disaster. A Japanese man, presumably in his 40s, got police protection in April 2016 but was unable to respond to question about his own name...
2017: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/28331002/personalized-in-vitro-and-in-vivo-cancer-models-to-guide-precision-medicine
#17
Chantal Pauli, Benjamin D Hopkins, Davide Prandi, Reid Shaw, Tarcisio Fedrizzi, Andrea Sboner, Verena Sailer, Michael Augello, Loredana Puca, Rachele Rosati, Terra J McNary, Yelena Churakova, Cynthia Cheung, Joanna Triscott, David Pisapia, Rema Rao, Juan Miguel Mosquera, Brian Robinson, Bishoy M Faltas, Brooke E Emerling, Vijayakrishna K Gadi, Brady Bernard, Olivier Elemento, Himisha Beltran, Francesca Demichelis, Christopher J Kemp, Carla Grandori, Lewis C Cantley, Mark A Rubin
Precision medicine is an approach that takes into account the influence of individuals' genes, environment, and lifestyle exposures to tailor interventions. Here, we describe the development of a robust precision cancer care platform that integrates whole-exome sequencing with a living biobank that enables high-throughput drug screens on patient-derived tumor organoids. To date, 56 tumor-derived organoid cultures and 19 patient-derived xenograft (PDX) models have been established from the 769 patients enrolled in an Institutional Review Board-approved clinical trial...
May 2017: Cancer Discovery
https://www.readbyqxmd.com/read/28330379/patient-self-defined-goals
#18
Sandra Ellen Schellinger, Eric Worden Anderson, Monica Schmitz Frazer, Cindy Lynn Cain
This research, a descriptive qualitative analysis of self-defined serious illness goals, expands the knowledge of what goals are important beyond the physical-making existing disease-specific guidelines more holistic. Integration of goals of care discussions and documentation is standard for quality palliative care but not consistently executed into general and specialty practice. Over 14 months, lay health-care workers (care guides) provided monthly supportive visits for 160 patients with advanced heart failure, cancer, and dementia expected to die in 2 to 3 years...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28327856/-interinstitutional-relations-for-person-centered-health
#19
Miguel R Jorge
Since 2005, when the World Psychiatric Association has launched its Institutional Program on Psychiatry for the Person, many different organizations have worked together to advance medical care from a disease-oriented challenge to a focus centered in the whole person. Nowadays, over 30 organizations are related in promoting person-centered medicine, from which some initiatives are highlighted.
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28323317/the-health-insurance-gap-after-implementation-of-the-affordable-care-act-in-texas
#20
Gordon Gong, Cassandra C Huey, Coleman Johnson, Debra Curti, Billy U Philips
Households with incomes between 18% and 99% of the federal poverty level (FPL) are ineligible for Medicaid or enrollment in the health insurance exchange marketplace in Texas, resulting in the health insurance gap. We sought to determine the number of non-elderly adult Texans (NEATs) aged between 18 and 64 years in the insurance gap in rural vs urban areas in East Texas, West Texas, and South Texas. Data were obtained from the US Census Bureau website. In 2014, there were 1,101,000 NEATs in the insurance gap, accounting for 24...
March 1, 2017: Texas Medicine
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