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https://www.readbyqxmd.com/read/29228523/advanced-therapeutic-gastrointestinal-endoscopy-in-children-today-and-tomorrow
#1
Zaheer Nabi, Duvvur Nageshwar Reddy
Gastrointestinal (GI) endoscopy plays an indispensable role in the diagnosis and management of various pediatric GI disorders. While the pace of development of pediatric GI endoscopy has increased over the years, it remains sluggish compared to the advancements in GI endoscopic interventions available in adults. The predominant reasons that explain this observation include lack of formal training courses in advanced pediatric GI interventions, economic constraints in establishing a pediatric endoscopy unit, and unavailability of pediatric-specific devices and accessories...
December 12, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/29228515/aging-and-cardiometabolic-risk-in-european-hems-pilots-an-assessment-of-occupational-old-age-limits-as-a-regulatory-risk-management-strategy
#2
Hans Bauer, Dennis Nowak, Britta Herbig
Old-age limits are imposed in some occupations in an effort to ensure public safety. In aviation, the "Age 60 Rule" limits permissible flight operations conducted by pilots aged 60 and over. Using a retrospective cohort design, we assessed this rule's validity by comparing age-related change rates of cardiometabolic incapacitation risk markers in European helicopter emergency medical service (HEMS) pilots near age 60 with those in younger pilots. Specifically, individual clinical, laboratory, and electrocardiogram (ECG)-based risk markers and an overall cardiovascular event risk score were determined from aeromedical examination records of 66 German, Austrian, Polish, and Czech HEMS pilots (average follow-up 8...
December 11, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/29228158/percutaneous-left-atrial-appendage-occlusion-in-atrial-fibrillation-patients-with-a-contraindication-to-oral-anticoagulation-a-focused-review
#3
Marin Nishimura, Shiv Sab, Ryan R Reeves, Jonathan C Hsu
Stroke is the most feared complication of atrial fibrillation (AF). Although oral anticoagulation with non-vitamin K antagonist and non-vitamin K antagonist oral anticoagulants (NOACs) have been established to significantly reduce risk of stroke, real-world use of these agents are often suboptimal due to concerns for adverse events including bleeding from both patients and clinicians. Particularly in patients with previous serious bleeding, oral anticoagulation may be contraindicated. Left atrial appendage occlusion (LAAO), mechanically targeting the source of most of the thrombi in AF, holds an immense potential as an alternative to OAC in management of stroke prophylaxis...
December 8, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29228145/rejuvenating-the-face-an-analysis-of-100-absorbable-suture-suspension-patients
#4
Michael Patrick Ogilvie, Julius Warren Few, Shikhar Singh Tomur, Chad Michael Teven, Alec James Semersky, Caroline Regan Bruno, Natasha Tamagni Kulick
Background: Absorbable suture suspension (Silhouette InstaLift, Sinclair Pharma, Irvine, CA) is a novel, minimally invasive system that utilizes a specially manufactured synthetic suture to help address the issues of facial aging, while minimizing the risks associated with historic thread lifting modalities. Objectives: The purpose of the study was to assess the safety, efficacy, and patient satisfaction of the absorbable suture suspension system in regards to facial rejuvenation and midface volume enhancement...
December 8, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29227526/bioactive-peptides-derived-from-seaweed-protein-and-their-health-benefits-antihypertensive-antioxidant-and-antidiabetic-properties
#5
REVIEW
Habtamu Admassu, Mohammed Abdalbasit A Gasmalla, Ruijin Yang, Wei Zhao
Cardiovascular diseases and diabetes are the biggest causes of death globally. Therefore, prevention of these diseases is a focus of pharmaceuticals and functional food manufacturers. This review summarizes recent research trends and scientific knowledge in seaweed protein-derived peptides with particular emphasis on production, isolation and potential health impacts in prevention of hypertension, diabetes and oxidative stress. The current status and future prospects of bioactive peptides are also discussed...
December 11, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29227357/risk-management-interventions-to-reduce-injuries-and-maximize-economic-benefits-in-u-s-mining
#6
Stephanie C Griffin, David P Bui, Gautam Gowrisankaran, Eric A Lutz, Charles He, Chengcheng Hu, Jefferey L Burgess
OBJECTIVE: Risk management (RM) is a cyclical process of identifying and ranking risks, implementing controls, and evaluating their effectiveness. This study aims to identify effective RM interventions in the U.S. mining industry. METHODS: RM interventions were identified in four companies representing metal, aggregate and coal mining sectors. Injury rates were determined using Mine Safety and Health Administration (MSHA) data and changes in injury rates identified through change point analysis...
December 8, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29226897/treatment-of-ineffective-endocardial-defibrillation-with-subcutaneous-array-a-case-report
#7
Özgür Kaplan, Sabri Demircan
Defibrillation threshold (DFT) testing is an important part of ICD implantation. After placement of the ICD generator, a DFT test is performed to evaluate the integrity of the ICD system and to confirm a successful defibrillation safety margin. More than 6% of ICDs implanted are not within the DFT safety margin. Presently described is the case of a patient with a high DFT and some of the methods that can be used to manage this circumstance, including the use of a subcutaneous array.
December 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29225918/correction-efficacy-and-safety-of-non-pharmacological-and-non-biological-pharmacological-treatment-a-systematic-literature-review-informing-the-2016-update-of-the-asas-eular-recommendations-for-the-management-of-axial-spondyloarthritis
#8
(no author information available yet)
[This corrects the article DOI: 10.1136/rmdopen-2016-000397.][This corrects the article DOI: 10.1136/rmdopen-2016-000397.].
2017: RMD Open
https://www.readbyqxmd.com/read/29225782/update-on-gh-therapy-in-adults
#9
REVIEW
Cesar Luiz Boguszewski
Over the last three decades, short- and long-term observational studies, clinical trials, systematic reviews, and meta-analyses have provided relevant information on the efficacy and safety of growth hormone (GH) replacement therapy in adults with GH deficiency (AGHD). The knowledge acquired during this time has been compiled into different guidelines that offer clinicians an evidence-based, practical approach for the management of AGHD. There are, however, still open questions in some key areas in which recommendations are supported by only moderate or weak evidence...
2017: F1000Research
https://www.readbyqxmd.com/read/29225003/improving-patient-safety-during-procedural-sedation-via-respiratory-volume-monitoring-a-randomized-controlled-trial
#10
Donald M Mathews, Michael J Oberding, Eric L Simmons, Stephen E O'Donnell, Kevin R Abnet, Kathleen MacDonald
STUDY OBJECTIVE: Assess the utility of a respiratory volume monitor (RVM) to reduce the incidence of low minute ventilation events in procedural sedation. DESIGN: Randomized control trial SETTING: Endoscopy suite PATIENTS: Seventy-three total patients (ASA Physical Status 1-3) undergoing upper endoscopies were analyzed. INTERVENTION: Patients were randomized into two groups using a computer generated randomization table: Control (n=41): anesthesia provider was unable to see the screen of the RVM; RVM (n=32): anesthesia provider had access to RVM data to assist with management of the case...
December 7, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/29224990/the-shift-to-same-day-outpatient-joint-arthroplasty-a-systematic-review
#11
REVIEW
Jeffrey D Hoffmann, Nicholas A Kusnezov, John C Dunn, Nicholas J Zarkadis, Gens P Goodman, Richard A Berger
BACKGROUND: Hip and knee arthroplasties length of stay continues to shorten after advances in perioperative and intraoperative management, as well as financial incentives. Some authors have demonstrated good results with outpatient arthroplasty, but safety and general feasibility of such procedures remain unclear. Our hypothesis is that outpatient arthroplasty would demonstrate higher readmission and complication rates than inpatient arthroplasty. METHODS: We performed a systematic review of all publications on outpatient arthroplasty between January 1, 2000 and June 1, 2016...
November 22, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29224861/a-survey-of-selected-animal-based-measures-of-dairy-cattle-welfare-in-the-eastern-alps-toward-context-based-thresholds
#12
A Zuliani, M Mair, M Kraševec, I Lora, M Brscic, G Cozzi, C Leeb, M Zupan, C Winckler, S Bovolenta
In the Alps, traditional dairy farms are small-scale operations where vertical transhumance from valley indoor housing systems to highland pasture-based systems is still practiced in summer. Vertical transhumance implies a substantial change of environment, available resources, and management practices from one season to another. In such systems, animal-based welfare measures need to be monitored throughout the year to capture the variation of welfare outcomes, based on which targeted welfare management plans can be implemented...
December 7, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29224633/over-the-counter-medicines-and-diabetes-care
#13
Jeff Taylor
OBJECTIVES: People with diabetes turn to over-the-counter (OTC) medicines for many ailments. The focus of this brief review is the impact common OTC medicines might have on this group of patients. METHODS: Three types of OTC medicines were selected as most deserving of attention: 3 herbal agents, nonsteroidal anti-inflammatory drugs (NSAIDs) and cough/cold products. Existing literature was used to determine precautions that might be in order. RESULTS: Herbal/natural agents with the potential to impact blood sugar have been identified in various reports...
December 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29223904/spatiotemporal-variations-of-hydrogeochemistry-and-its-controlling-factors-in-the-gandaki-river-basin-central-himalaya-nepal
#14
Ramesh Raj Pant, Fan Zhang, Faizan Ur Rehman, Guanxing Wang, Ming Ye, Chen Zeng, Handuo Tang
The characterization and assessment of water quality in the head water region of Himalaya is necessary, given the immense importance of this region in sustaining livelihoods of people and maintaining ecological balance. A total of 165 water samples were collected from 55 sites during pre-monsoon, monsoon and post-monsoon seasons in 2016 from the Gandaki River Basin of the Central Himalaya, Nepal. The pH, EC values and TDS concentrations were measured in-situ and the concentrations of major ions (Ca2+, Mg2+, K+, Na+, Cl-, SO42-, NO3-) and Si were analyzed in laboratory...
December 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29223767/evaluation-of-a-national-pediatric-subinternship-curriculum-implemented-through-individual-learning-plans
#15
Linda R Tewksbury, Cristina Carter, Lyuba Konopasek, Sandra M Sanguino, Janice L Hanson
OBJECTIVE: The Council on Medical Student Education in Pediatrics and Association of Pediatric Program Directors developed a Pediatric Subinternship (CAPS) Curriculum for use with an individualized learning plan (ILP). The authors determined which learning objectives (LOs) pediatric subinterns selected when provided the CAPS Curriculum, summarized students' self-reported progress, and determined feasibility of ILPs in subinternship. METHODS: Students from 10 medical schools completed a standardized ILP during pediatric subinternship...
December 6, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/29223760/down-the-local-a-qualitative-case-study-of-daytime-drinking-spaces-in-the-london-borough-of-islington
#16
Claire Thompson, Sarah Milton, Matt Egan, Karen Lock
BACKGROUND: Recognising the lack of research on daytime drinking practices in areas with managed night-time economies (NTEs), this qualitative study explores the phenomena in the London Borough of Islington; a rapidly gentrifying area with a highly regulated night-time economy (NTE). The objectives were to (i) Characterise the daytime drinking spaces of the local alcohol environment and (ii) Theorise the ways in which these spaces, and the practices and performativities within them, are situated within broader social and economic trends...
December 7, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29223524/gamma-knife-stereotactic-radiosurgery-for-non-vestibular-cranial-nerve-schwannomas
#17
Anne-Marie Langlois, Christian Iorio-Morin, Laurence Masson-Côté, David Mathieu
BACKGROUND: Non-vestibular cranial schwannomas represent a rare type of benign intracranial tumor. Few studies have evaluated the use of stereotactic radiosurgery (SRS) as a primary management option for these lesions. We therefore performed a retrospective review of our institution's experience focussing on efficacy with regards to tumor control and clinical symptom stabilization, as well as treatment safety. METHODS: Patients were included if they underwent at least one SRS procedure for a non-vestibular schwannoma and had at least 6 months of available imaging follow-up...
December 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29223441/edoxaban-for-the-management-of-elderly-japanese-patients-with-atrial-fibrillation-ineligible-for-standard-oral-anticoagulant-therapies-rationale-and-design-of-the-eldercare-af-study
#18
Ken Okumura, Gregory Y H Lip, Masaharu Akao, Kimihiko Tanizawa, Masayuki Fukuzawa, Kenji Abe, Masahiro Akishita, Takeshi Yamashita
Edoxaban-a non-vitamin K antagonist oral anticoagulant (NOAC)- 60-mg and 30-mg once-daily dose regimens are noninferior versus well-managed warfarin for the prevention of stroke or systemic embolic events (SEE) with less major bleeding in patients with nonvalvular atrial fibrillation (NVAF). There are no published data from phase 3 clinical trials specifically evaluating the use of NOACs in elderly NVAF patients, especially those considered ineligible for available oral anticoagulants. The Edoxaban Low-Dose for EldeR CARE AF patients (ELDERCARE-AF) study is a phase 3, randomized, double-blind, placebo-controlled, parallel-group, multicenter study that will compare the safety and efficacy of once-daily edoxaban 15 mg versus placebo in Japanese patients with NVAF ≥80 years of age who are considered ineligible for standard oral anticoagulant therapy...
December 2017: American Heart Journal
https://www.readbyqxmd.com/read/29223192/training-needs-for-dementia-care-in-china-from-the-perspectives-of-mental-health-providers-who-what-and-how
#19
Ling Xu, Hsin-Yi Hsiao, Wenchen Denq, Iris Chi
BACKGROUND: Acknowledging increasing demand of dementia care for patients in China, this paper aims to understand the training needs of dementia care from the perspectives of mental health providers by examining who should be the trainees, what should be the contents of training, and how to deliver the training in China. METHODS: Using purposive sampling, data were gathered via four focus group discussions with 40 mental health providers in Beijing, China, in 2011...
December 10, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/29223139/novel-treatments-for-inflammatory-bowel-disease
#20
Hyo Sun Lee, Soo-Kyung Park, Dong Il Park
Increased understanding of the immunopathology of inflammatory bowel disease (IBD) has led to the development of targeted therapies and has unlocked a new era in IBD treatment. The development of treatment options aimed at a variety of pathological mechanisms offers new hope for customized therapies. Beyond anti-tumor necrosis factor agents, selective lymphocyte trafficking inhibitors have been proposed as potent drugs for IBD. Among these, vedolizumab has recently been approved for both Crohn's disease and ulcerative colitis...
December 11, 2017: Korean Journal of Internal Medicine
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