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https://www.readbyqxmd.com/read/29684580/exploring-the-influence-of-nursing-work-environment-and-patient-safety-culture-on-missed-nursing-care-in-korea
#1
Kyoung-Ja Kim, Moon Sook Yoo, Eun Ji Seo
PURPOSE: This study aimed to explore the influence of nurse work environment and patient safety culture in hospital on instances of missed nursing care in South Korea. METHODS: A cross-sectional design was used, in which a structured questionnaire was administered to 186 nurses working at a tertiary university hospital. Data were analyzed using descriptive statistics, t-test or ANOVA, Pearson correlation and multiple regression analysis. RESULTS: Missed nursing care was found to be correlated with clinical career, nursing work environment and patient safety culture...
April 20, 2018: Asian Nursing Research
https://www.readbyqxmd.com/read/29684232/immune-checkpoint-inhibitor-therapy-in-patients-with-autoimmune-disease
#2
Douglas B Johnson, Kathryn E Beckermann, Daniel Y Wang
Immune checkpoint inhibitors have demonstrated efficacy across many cancer types in numerous clinical trials. However, because patients with preexisting autoimmune disease were excluded from these seminal trials, there are serious gaps in knowledge regarding the efficacy-and in particular the safety-of these transformative agents in patients with autoimmune disease. The safety of immune checkpoint inhibitors in this population has been an important concern, since these agents unleash immune activation, a potentially dangerous situation for patients with already heightened and aberrant immune function...
April 15, 2018: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/29683736/helping-nurses-help-pivcs-decision-aids-for-daily-assessment-and-maintenance
#3
Gillian Ray-Barruel, Claire M Rickard
Improving the safety and quality of health care relies on implementing evidence-based findings into every-day clinical practice. Numerous clinical decision aids have been developed to guide nursing care of the patient with a peripheral intravenous catheter (PIVC), including standards, guidelines, decision frameworks, bundles, policies, procedures, algorithms, pathways, checklists and scoring tools. While all are created with the intention of facilitating the delivery of safe, effective nursing care and improving patient outcomes, there are distinct differences in methodology and design between them, and many are based on expert opinion and historical practice rather than high-quality evidence...
April 26, 2018: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/29683728/healthcare-providers-attitudes-and-behaviours-related-to-paediatric-mild-traumatic-brain-injury-results-from-the-2014-docstyles-survey
#4
Kelly Sarmiento, Zoe Donnell, Rosanne Hoffman, Bethany Tennant
OBJECTIVE: Explore healthcare providers' experiences managing mTBI and better understand their use of mTBI assessment tools and guidelines. Cross-sectional Methods: A random sample of 1,760 healthcare providers responded to the web-based DocStyles survey between June 18 and 30, 2014. The sample included family/general practitioners, internists, pediatricians, and nurse practitioners who reported seeing pediatric patients. We examined their experiences with mTBI to identify opportunities to increase preparedness and improve management of mTBI...
April 23, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29683474/antidepressants-for-the-treatment-of-depression-in-people-with-cancer
#5
REVIEW
Giovanni Ostuzzi, Faith Matcham, Sarah Dauchy, Corrado Barbui, Matthew Hotopf
BACKGROUND: Major depression and other depressive conditions are common in people with cancer. These conditions are not easily detectable in clinical practice, due to the overlap between medical and psychiatric symptoms, as described by diagnostic manuals such as the Diagnostic and Statistical Manual of Mental Disorders (DSM) and International Classification of Diseases (ICD). Moreover, it is particularly challenging to distinguish between pathological and normal reactions to such a severe illness...
April 23, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29683362/immunogenicity-of-biologic-therapies-causes-and-consequences
#6
Wolf-Henning Boehncke, Nicolo Costantino Brembilla
Antibodies or fusion proteins termed biologics allow the targeted therapy of diseases. Many of these agents have proven superior efficacy and safety to conventional therapies, and subsequently revolutionized the management of numerous chronic diseases. Repetitive administration of these protein-based therapeutics to immunocompetent patients elicit immune responses in the form of Anti Drug Antibodies (ADAs), which in turn impact their pharmacological properties and may trigger adverse events. Areas covered: Structural characteristics determining the immunogenicity of biologics are reviewed along with strategies to minimize it...
April 23, 2018: Expert Review of Clinical Immunology
https://www.readbyqxmd.com/read/29682995/efficacy-and-safety-of-the-combination-of-isosorbide-dinitrate-spray-and-chitosan-gel-for-the-treatment-of-diabetic-foot-ulcers-a-double-blind-randomized-clinical-trial
#7
Sylvia Elena Totsuka Sutto, Yunuen Itzet Rodríguez Roldan, Ernesto German Cardona Muñoz, Teresa Arcelia Garcia Cobian, Sara Pascoe Gonzalez, Abril Martínez Rizo, Miriam Mendez Del Villar, Leonel García Benavides
AIM: To evaluate whether a combination of isosorbide dinitrate spray and chitosan gel (10%) topically applied can have additive benefits for management of diabetic foot ulcers. METHODS: In a randomized, placebo-controlled, double-blinded clinical trial, 68 patients were divided into four groups: Group 1: treated with chitosan gel; Group 2: isosorbide dinitrate spray; Group 3: combination of isosorbide dinitrate spray and chitosan gel; Group 4: placebo. RESULTS: Histological analyses showed a significant regeneration in all groups ( p < 0...
April 1, 2018: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/29682843/chronic-condition-self-management-support-for-aboriginal-people-adapting-tools-and-training
#8
Malcolm Battersby, Sharon Lawn, Inge Kowanko, Sue Bertossa, Coral Trowbridge, Raylene Liddicoat
PROBLEM: Chronic conditions are major health problems for Australian Aboriginal people. Self-management programs can improve health outcomes. However, few health workers are skilled in self-management support and existing programs are not always appropriate in Australian Aboriginal contexts. DESIGN: The goal was to increase the capacity of the Australian health workforce to support Australian Aboriginal people to self-manage their chronic conditions by adapting the Flinders Program of chronic condition self-management support for Australian Aboriginal clients and develop and deliver training for health professionals to implement the program...
April 22, 2018: Australian Journal of Rural Health
https://www.readbyqxmd.com/read/29682628/the-adverse-outcome-pathway-a-multifaceted-framework-supporting-21-st-century-toxicology
#9
Gerald T Ankley, Stephen W Edwards
The adverse outcome pathway (AOP) framework serves as a knowledge assembly, interpretation, and communication tool designed to support the translation of pathway-specific mechanistic data into responses relevant to assessing and managing risks of chemicals to human health and the environment. As such, AOPs facilitate the use of data streams often not employed by risk assessors, including information from in silico models, in vitro assays and short-term in vivo tests with molecular/biochemical endpoints. This translational capability can increase the capacity and efficiency of safety assessments both for single chemicals and chemical mixtures...
June 1, 2018: Current Opinion in Toxicology
https://www.readbyqxmd.com/read/29682617/improving-local-anaesthetic-systemic-toxicity-last-awareness-in-maternity-care-using-tailored-educational-tools
#10
Amy E Edwards, Gemma M Bowsher, Sahil Deepak, Mohamed Ali
Local anaesthetic (LA) agents are widely used in maternity care. Although relatively safe, their use does carry risks, the most serious of which is systemic toxicity (LAST). LAST poses a major threat to maternal and neonatal safety due to the frequency of LA administration in maternity care and the under-recognition of toxicity in such settings, which has been reported globally. Our aim was to prevent LAST occurrence in a District General Hospital (DGH) maternity unit by improving staff awareness through the implementation of a tailored educational programme...
2018: BMJ Open Quality
https://www.readbyqxmd.com/read/29682533/bilateral-hip-arthroplasty-when-is-it-safe-to-operate-the-second-hip-a-systematic-review
#11
REVIEW
Meilyn Muskus, Jorge Rojas, Camilo Gutiérrez, Juan Guio, Guillermo Bonilla, Adolfo Llinás
Introduction: Patients with degenerative hip disease frequently present with bilateral involvement that requires surgical management. The main goal when treating these patients is to achieve the maximum efficiency without increasing risk of perioperative complications; therefore, the decision regarding the best moment to operate the second hip becomes relevant. Although studies have addressed this topic, whether a simultaneous or staged surgery should be performed remains controversial...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29682466/video-assisted-thoracoscopic-plasmajet-ablation-for-malignant-pleural-mesothelioma
#12
Periklis Perikleous, Nizar Asadi, Vladimir Anikin
The role of surgery in malignant pleural mesothelioma (MPM) remains debatable; nonetheless the relative advantages of different surgical approaches are frequently reassessed and reconsidered. While extensive operations and longer recovery periods can be justified for a group of carefully selected patients, many will present at an advanced stage of their disease or with associated co-morbidities which will exclude them from selection criteria for radical treatment. For these patients, minimally invasive video-assisted procedures may be considered, for purposes of cytoreduction and/or symptomatic relief...
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29682132/creating-a-foundation-for-implementing-an-electronic-health-records-ehr-integrated-social-knowledge-networking-skn-system-on-medication-reconciliation
#13
P Rangachari, K C Dellsperger, D Fallaw, I Davis, M Sumner, W Ray, S Fiedler, T Nguyen, R Rethemeyer
Background: In fall 2016, Augusta University received a two-year grant from AHRQ, to implement a Social Knowledge Networking (SKN) system for enabling its health system, AU-Health, to progress from "limited use" of EHR Medication Reconciliation (MedRec) Technology, to "meaningful use." Phase 1 sought to identify a comprehensive set of issues related to EHR MedRec encountered by practitioners at AU-Health. These efforts helped develop a Reporting Tool , which, along with a Discussion Tool , was incorporated into the AU-Health EHR, at the end of Phase 1...
April 2018: Journal of Hospital Administration
https://www.readbyqxmd.com/read/29681631/management-of-medical-care-a-fundamental-tool-for-resident-doctors
#14
Guillermo Fajardo-Ortiz, Héctor Robledo
In the area of medical education, and particularly in our country, medical residencies are the best educational programs for a graduated physicians; however, when young medical doctors begin a residence at hospitals, they hardly poses knowledge about the way medical services work as well as the processes they involve, which directly affects the fulfillment of their tasks, their process of learning and more importantly, it interferes in the services provided by the hospital. Therefore, it is imperative to immerse residents in the management of medical care and let them know that its main function is to harmoniously articulate every medical-administrative process related to patients as well as human, material and financial resources...
2018: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/29681585/clinical-outcomes-of-subintimal-vs-intraluminal-revascularization-approaches-for-long-femoropopliteal-occlusions-in-a-korean-multicenter-retrospective-registry-cohort
#15
Kyu Kim, Young-Guk Ko, Chul-Min Ahn, Pil-Ki Min, Jae-Hwan Lee, Chang-Hwan Yoon, Cheol Woong Yu, Seung Whan Lee, Sang-Rok Lee, Seung Hyuk Choi, Yoon Seok Koh, In-Ho Chae, Donghoon Choi
BACKGROUND: There are limited data comparing the outcomes of subintimal vs. intraluminal approach in the treatment of long femoropopliteal artery occlusions. The objective of this study was to investigate the efficacy and safety of the subintimal approach for long femoropopliteal artery occlusions.Methods and Results:From a multicenter retrospective registry cohort, we included a total of 461 patients with 487 femoropopliteal artery occlusions classified as Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC) II C/D for this analysis...
April 20, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29681256/carer-and-clinician-perceptions-of-the-use-of-emergency-medical-services-by-people-with-dementia-a-qualitative-study
#16
Sarah Voss, Janet Brandling, Sarah Black, Rik Cheston, Sarah Cullum, Steve Iliffe, Sarah Purdy, Jonathan Benger
A growing number of older people are accessing emergency medical services (EMS), and many calls to EMS are made by, or on behalf of, people with dementia. Their needs are frequently complex; however, EMS staff are often given minimal guidance on ensuring patient safety, accurate diagnosis, and timely transfer to the most appropriate care. This study aimed to qualitatively explore the EMS experiences of carers for people with dementia and assess the views of EMS staff on the management of dementia, using focus groups and interviews...
April 23, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29681173/consensus-statement-on-use-of-continuous-subcutaneous-insulin-infusion-therapy-in-the-hospital
#17
Bithika Thompson, Mary Korytkowski, David C Klonoff, Curtiss B Cook
In May 2017, the Diabetes Technology Society convened a panel of US experts on inpatient diabetes management to discuss the current and potential role of continuous subcutaneous insulin infusion (CSII) therapy in the hospital. The panel (1) discussed evidence for current use of CSII in the hospital, (2) recommended contraindications for use in the hospital, and (3) recommended guidelines to maximize chances for safe use of CSII in the hospital. Panel members agreed that larger, prospective, randomized studies are needed to evaluate safety and efficacy of CSII use in the hospital...
April 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29681109/safety-and-efficacy-of-noncardiac-surgical-procedures-in-the-management-of-patients-with-trisomy-13-a-single-institution-based-detailed-clinical-observation
#18
Soichi Shibuya, Yuichiro Miyake, Shigeru Takamizawa, Eriko Nishi, Katsumi Yoshizawa, Tomoko Hatata, Kazuki Yoshizawa, Kenya Fujita, Masahiko Noguchi, Jun Ohata, Takehiko Hiroma, Tomohiko Nakamura, Tomoki Kosho
Intensive treatment including surgery for patients with trisomy 13 (T13) remains controversial. This study aimed to evaluate the safety and efficacy of noncardiac surgical intervention for T13 patients. Medical records of patients with karyotypically confirmed T13 treated in the neonatal intensive care unit in Nagano Children's Hospital from January 2000 to October 2016 were retrospectively reviewed, and data from patients who underwent noncardiac surgery were analyzed. Of the 20 patients with T13, 15 (75%) underwent a total of 31 surgical procedures comprising 15 types, including tracheostomy in 10 patients and gastrostomy in 4...
May 2018: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/29680884/ecotoxicological-effects-of-microplastics-on-biota-a-review
#19
Sadasivam Anbumani, Poonam Kakkar
The ubiquitous presence of microplastics in the environment has drawn the attention of ecotoxicologists on its safety and toxicity. Sources of microplastics in the environment include disintegration of larger plastic items (secondary microplastics), personal care products like liquid soap, exfoliating scrubbers, and cleaning supplies etc. Indiscriminate usage of plastics and its poor waste disposal management pose serious concern on ecosystem quality at global level. The present review focused on the ecological impact of microplastics on biota at different trophic levels, its uptake, accumulation, and excretion etc...
April 21, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29680865/comparison-of-midterm-outcomes-of-transcatheter-aortic-valve-implantation-in-patients-with-and-without-previous-coronary-artery-bypass-grafting
#20
Hideyuki Kawashima, Yusuke Watanabe, Ken Kozuma, Akihisa Kataoka, Makoto Nakashima, Hirofumi Hioki, Fukuko Nagura, Yugo Nara, Shinichi Shirai, Norio Tada, Motoharu Araki, Toru Naganuma, Futoshi Yamanaka, Hiroshi Ueno, Minoru Tabata, Kazuki Mizutani, Akihiro Higashimori, Kensuke Takagi, Masanori Yamamoto, Kentaro Hayashida
The midterm safety and feasibility of transcatheter aortic valve implantation (TAVI) for patients with a history of coronary artery bypass graft (CABG) and high operative risk are unclear. This study compared the midterm outcomes of patients undergoing TAVI with or without previous CABG surgery. Between October 2013 and July 2016, 1,613 patients underwent TAVI according to the Optimized CathEter vAlvular iNtervention (OCEAN)-TAVI registry (previous CABG: n = 120; no previous CABG: n = 1493). The propensity score comprised the variables of the Society of Thoracic Surgeons Score, previous myocardial infarction, peripheral artery disease, chronic kidney disease > stage 2 (estimated glomerular filtration rate < 60 mL/min/1...
April 21, 2018: Heart and Vessels
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