keyword
MENU ▼
Read by QxMD icon Read
search

Jaspers

keyword
https://www.readbyqxmd.com/read/29333673/predicting-heart-failure-one-size-does-not-fit-all
#1
EDITORIAL
Jasper Tromp, Peter van der Meer
No abstract text is available yet for this article.
January 15, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29330763/safe-and-sensible-preprocessing-and-baseline-correction-of-pupil-size-data
#2
Sebastiaan Mathôt, Jasper Fabius, Elle Van Heusden, Stefan Van der Stigchel
Measurement of pupil size (pupillometry) has recently gained renewed interest from psychologists, but there is little agreement on how pupil-size data is best analyzed. Here we focus on one aspect of pupillometric analyses: baseline correction, i.e., analyzing changes in pupil size relative to a baseline period. Baseline correction is useful in experiments that investigate the effect of some experimental manipulation on pupil size. In such experiments, baseline correction improves statistical power by taking into account random fluctuations in pupil size over time...
January 12, 2018: Behavior Research Methods
https://www.readbyqxmd.com/read/29327797/potassium-and-the-use-of-renin-angiotensin-aldosterone-system-inhibitors-in-heart-failure-with-reduced-ejection-fraction-data-from-biostat-chf
#3
Joost C Beusekamp, Jasper Tromp, Haye H van der Wal, Stefan D Anker, John G Cleland, Kenneth Dickstein, Gerasimos Filippatos, Pim van der Harst, Hans L Hillege, Chim C Lang, Marco Metra, Leong L Ng, Piotr Ponikowski, Nilesh J Samani, Dirk J van Veldhuisen, Aeilko H Zwinderman, Patrick Rossignol, Faiez Zannad, Adriaan A Voors, Peter van der Meer
BACKGROUND: Hyperkalaemia is a common co-morbidity in patients with heart failure with reduced ejection fraction (HFrEF). Whether it affects the use of renin-angiotensin-aldosterone system inhibitors and thereby negatively impacts outcome is unknown. Therefore, we investigated the association between potassium and uptitration of angiotensin-converting enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARB) and its association with outcome. METHODS AND RESULTS: Out of 2516 patients from the BIOSTAT-CHF study, potassium levels were available in 1666 patients with HFrEF...
January 12, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29325071/viral-suppressors-of-rnai-employ-a-rapid-screening-mode-to-discriminate-viral-rna-from-cellular-small-rna
#4
Mohamed Fareh, Jasper van Lopik, Iason Katechis, Alfred W Bronkhorst, Anna C Haagsma, Ronald P van Rij, Chirlmin Joo
RNA interference (RNAi) is an indispensable mechanism for antiviral defense in insects, including mosquitoes that transmit human diseases. To escape this antiviral defense system, viruses encode suppressors of RNAi that prevent elimination of viral RNAs, and thus ensure efficient virus accumulation. Although the first animal Viral Suppressor of RNAi (VSR) was identified more than a decade ago, the molecular basis of RNAi suppression by these viral proteins remains unclear. Here, we developed a single-molecule fluorescence assay to investigate how VSRs inhibit the recognition of viral RNAs by Dcr-2, a key endoribonuclease enzyme in the RNAi pathway...
January 9, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29324408/assessing-dynamic-balance-performance-during-exergaming-based-on-speed-and-curvature-of-body-movements
#5
Venustiano Soancatl Aguilar, Jasper J van de Gronde, Claudine J C Lamoth, Natasha M Maurits, Jos B T M Roerdink
Improving balance performance among the elderly is of utmost importance because of the increasing number of injuries and fatalities caused by fall incidences. Digital games controlled by body movements (exergames) have been proposed as a way to improve balance among older people. However, the assessment of balance performance in real-time during exergaming remains a challenging task. This assessment could be used to provide instantaneous feedback and automatically adjust the exergame difficulty. Such features could potentially increase the motivation of the player, thus augmenting the effectiveness of exergames...
January 2018: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29319806/comparative-genomics-highlights-symbiotic-capacities-and-high-metabolic-flexibility-of-the-marine-genus-pseudovibrio
#6
Dennis Versluis, Bart Nijsse, Mohd Azrul Naim, Jasper J Koehorst, Jutta Wiese, Johannes F Imhoff, Peter J Schaap, Mark W J van Passel, Hauke Smidt, Detmer Sipkema
Pseudovibrio is a marine bacterial genus members of which are predominantly isolated from sessile marine animals, and particularly sponges. It has been hypothesised that Pseudovibrio spp. form mutualistic relationships with their hosts. Here, we studied Pseudovibrio phylogeny and genetic adaptations that may play a role in host colonization by comparative genomics of 31 Pseudovibrio strains, including 25 sponge isolates. All genomes were highly similar in terms of encoded core metabolic pathways, albeit with substantial differences in overall gene content...
January 8, 2018: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29317433/improved-evaluation-of-antivascular-cancer-therapy-using-constrained-tracer-kinetic-modeling-for-multi-agent-dynamic-contrast-enhanced-mri
#7
Stefanie Hectors, Igor Jacobs, Jasper Lok, Johannes Peters, Johan Bussink, Freek J M Hoeben, Henk Keizer, Henk M Janssen, Klaas Nicolay, Matthias Schabel, Gustav Strijkers
Dynamic contrast-enhanced MRI (DCE-MRI) is a promising technique for assessing the response of tumor vasculature to anti-vascular therapies. Multi-agent DCE-MRI employs a combination of low and high molecular weight contrast agents, which potentially improves the accuracy of estimation of tumor hemodynamic and vascular permeability parameters. In this study, we employed multi-agent DCE-MRI to assess changes in tumor hemodynamics and vascular permeability after vascular-disrupting therapy. Multi-agent DCE-MRI (sequential injection of G5 dendrimer, G2 dendrimer, and Gd-DOTA) was performed in tumor-bearing mice before, 2 h and 24 h after treatment with vascular disrupting agent DMXAA or placebo...
January 9, 2018: Cancer Research
https://www.readbyqxmd.com/read/29316583/-foreign-body-ingestion-a-rare-cause-of-abdominal-pain
#8
Philipp Kasper, Fabian Kütting, Hans Anton Schlößer, Stefan Paul Mönig, Tobias Goeser, Natalie Jaspers
HISTORY AND FINDINGS UPON ADMISSION:  A 50-year-old man presented at the emergency unit with abdominal pain in the right lower quadrant and dysuria. He described an increase in pain during micturition. EXAMINATIONS:  After multiple examinations (CT-scan, MR-scan, ileocolonoscopy) were performed to no avail, a toothpick was detected in the terminal ileum during an ultrasound scan of the small intestine. Prompted elevation of intra-abdominal pressure led to migration of the radiolucent sharp foreign body into the wall of the urinary bladder, inducing pain...
January 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29313671/cluster-formation-in-the-superconducting-complex-intermetallic-compound-be21pt5
#9
Alfred Amon, Alim Ormeci, Matej Bobnar, Lev G Akselrud, Maxim Avdeev, Roman Gumeniuk, Ulrich Burkhardt, Yurii Prots, Christoph Hennig, Andreas Leithe-Jasper, Yuri Grin
Materials with the crystal structure of γ-brass type (Cu5Zn8 type) are typical representatives of intermetallic compounds. From the electronic point of view, they are often interpreted using the valence electron concentration approach of Hume-Rothery, developed previously for transition metals. The γ-brass-type phases of the main-group elements are rather rare. The intermetallic compound Be21Pt5, a new member of this family, was synthesized, and its crystal structure, chemical bonding, and physical properties were characterized...
January 9, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29306747/heterocellular-3d-scaffolds-as-biomimetic-to-recapitulate-the-tumor-microenvironment-of-peritoneal-metastases-in%C3%A2-vitro-and-in%C3%A2-vivo
#10
Emiel De Jaeghere, Elly De Vlieghere, Jasper Van Hoorick, Sandra Van Vlierberghe, Glenn Wagemans, Leen Pieters, Elodie Melsens, Marleen Praet, Jo Van Dorpe, Matthieu N Boone, Rouba Ghobeira, Nathalie De Geyter, Marc Bracke, Christian Vanhove, Sara Neyt, Geert Berx, Bruno G De Geest, Peter Dubruel, Heidi Declercq, Wim Ceelen, Olivier De Wever
Peritoneal metastasis is a major cause of death and preclinical models are urgently needed to enhance therapeutic progress. This study reports on a hybrid hydrogel-polylactic acid (PLA) scaffold that mimics the architecture of peritoneal metastases at the qualitative, quantitative and spatial level. Porous PLA scaffolds with controllable pore size, geometry and surface properties are functionalized by type I collagen hydrogel. Co-seeding of cancer-associated fibroblasts (CAF) increases cancer cell adhesion, recovery and exponential growth by in situ heterocellular spheroid formation...
December 23, 2017: Biomaterials
https://www.readbyqxmd.com/read/29303807/mucus-microbiome-of-anastomotic-tissue-during-surgery-has-predictive-value-for-colorectal-anastomotic-leakage
#11
Jasper B van Praagh, Marcus C de Goffau, Ilsalien S Bakker, Harry van Goor, Hermie J M Harmsen, Peter Olinga, Klaas Havenga
OBJECTIVE: The aim of the present study is to investigate the association of gut microbiota, depending on treatment method, with the development of colorectal anastomotic leakage (AL). BACKGROUND: AL is a major cause for morbidity and mortality after colorectal surgery, but the mechanism behind this complication still is not fully understood. METHODS: Bacterial DNA was isolated from 123 "donuts" of patients where a stapled colorectal anastomosis was made and was analyzed using 16S MiSeq sequencing...
January 4, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29302676/linking-slow-dynamics-and-microscopic-connectivity-in-dense-suspensions-of-charged-colloids
#12
Ruben Higler, Johannes Krausser, Jasper van der Gucht, Alessio Zaccone, Joris Sprakel
The quest to unravel the nature of the glass transition, where the viscosity of a liquid increases by many orders of magnitude, while its static structure remains largely unaffected, remains unresolved. While various structural and dynamical precursors to vitrification have been identified, a predictive and quantitative description of how subtle changes at the microscopic scale give rise to the steep growth in macroscopic viscosity is missing. It was recently proposed that the presence of long-lived bonded structures within the liquid may provide the long-sought connection between local structure and global dynamics...
January 5, 2018: Soft Matter
https://www.readbyqxmd.com/read/29301059/objective-validation-of-perfusion-based-human-cadaveric-simulation-training-model-for-management-of-internal-carotid-artery-injury-in-endoscopic-endonasal-sinus-and-skull-base-surgery
#13
Jasper Shen, Kevin Hur, Zhipeng Zhang, Michael Minneti, Martin Pham, Bozena Wrobel, Gabriel Zada
BACKGROUND: The emergence of minimally invasive endoscopic endonasal skull base surgery has necessitated reproducible and realistic simulators of rare vascular injuries. OBJECTIVE: To assess the face and content validity of an innovative perfusion-based cadaveric model developed to simulate internal carotid artery (ICA) injury during endoscopic surgery. METHODS: Otolaryngology and neurosurgery trainees attempted 3 consecutive trials of endoscopic control of a parasellar ICA injury, with standardized technical feedback...
December 29, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29290494/high-and-immeasurable-ankle-brachial-index-as-predictor-of%C3%A2-poor-amputation-free-survival-in-critical-limb-ischemia
#14
Marlon I Spreen, Hendrik Gremmels, Martin Teraa, Ralf W Sprengers, Jasper M Martens, Marianne C Verhaar, Jan J Wever, Gert J de Borst, Jan A Vos, Willem P Th M Mali, Hans van Overhagen
OBJECTIVE: The objective of this study was to assess the prognostic value of a high or immeasurable ankle-brachial index (ABI) at baseline for major amputation and amputation-free survival (AFS) in patients with critical limb ischemia (CLI). METHODS: Data from two recent trials in patients with CLI and proven infrapopliteal arterial obstructive disease were pooled. Patients were allocated to the low (<0.7), intermediate (0.7-1.4), or high (>1.4)/immeasurable ABI subgroup...
December 28, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29286445/3d-ultrasound-imaging-fast-and-cost-effective-morphometry-of-musculoskeletal-tissue
#15
Guido Weide, Stephan van der Zwaard, Peter A Huijing, Richard T Jaspers, Jaap Harlaar
The developmental goal of 3D ultrasound imaging (3DUS) is to engineer a modality to perform 3D morphological ultrasound analysis of human muscles. 3DUS images are constructed from calibrated freehand 2D B-mode ultrasound images, which are positioned into a voxel array. Ultrasound (US) imaging allows quantification of muscle size, fascicle length, and angle of pennation. These morphological variables are important determinants of muscle force and length range of force exertion. The presented protocol describes an approach to determine volume and fascicle length of m...
November 27, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29284752/role-of-enhanced-receptor-engagement-in-the-evolution-of-a-pandemic-acute-hemorrhagic-conjunctivitis-virus
#16
Jim Baggen, Daniel L Hurdiss, Georg Zocher, Nitesh Mistry, Richard W Roberts, Jasper J Slager, Hongbo Guo, Arno L W van Vliet, Maryam Wahedi, Kimberley Benschop, Erwin Duizer, Cornelis A M de Haan, Erik de Vries, José M Casasnovas, Raoul J de Groot, Niklas Arnberg, Thilo Stehle, Neil A Ranson, Hendrik Jan Thibaut, Frank J M van Kuppeveld
Acute hemorrhagic conjunctivitis (AHC) is a painful, contagious eye disease, with millions of cases in the last decades. Coxsackievirus A24 (CV-A24) was not originally associated with human disease, but in 1970 a pathogenic "variant" (CV-A24v) emerged, which is now the main cause of AHC. Initially, this variant circulated only in Southeast Asia, but it later spread worldwide, accounting for numerous AHC outbreaks and two pandemics. While both CV-A24 variant and nonvariant strains still circulate in humans, only variant strains cause AHC for reasons that are yet unknown...
December 28, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29283691/relationships-between-the-external-and-internal-training-load-in-professional-soccer-what-can-we-learn-from-machine-learning
#17
Arne Jaspers, Tim Op De Beéck, Michel S Brink, Wouter G P Frencken, Filip Staes, Jesse J Davis, Werner F Helsen
PURPOSE: Machine learning may contribute to understanding the relationship between the external load and internal load in professional soccer. Therefore, the relationship between external load indicators and the rating of perceived exertion (RPE) was examined using machine learning techniques on a group and individual level. METHODS: Training data were collected from 38 professional soccer players over two seasons. The external load was measured using global positioning system technology and accelerometry...
December 28, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/29281095/proximal-and-distal-occlusion-of-complex-cerebral-aneurysms-implications-of-flow-modeling-by-fluid-structure-interaction-analysis
#18
Jasper H G Helthuis, Sindhoor Bhat, Tristan P C van Doormaal, Ramarathnam Krishna Kumar, Albert van der Zwan
BACKGROUND: In complex cerebral aneurysms, adequate treatment by complete occlusion is not always possible. Partial occlusion by either proximal or distal occlusion is an alternative. However, the hemodynamic consequences of these partial occlusion options are often not easily predictable. OBJECTIVE: To assess the feasibility of fluid-structure interaction (FSI) analysis to investigate the hemodynamic changes after partial occlusion in cerebral aneurysms. METHODS: Two patients were analyzed...
December 21, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29279933/effect-of-antibiotic-prophylaxis-on-surgical-site-infections-following-removal-of-orthopedic-implants-used-for-treatment-of-foot-ankle-and-lower-leg-fractures-a-randomized-clinical-trial
#19
RANDOMIZED CONTROLLED TRIAL
Manouk Backes, Siem A Dingemans, Marcel G W Dijkgraaf, H Rogier van den Berg, Bart van Dijkman, Jochem M Hoogendoorn, Pieter Joosse, Ewan D Ritchie, W Herbert Roerdink, Judith P M Schots, Nico L Sosef, Ingrid J B Spijkerman, Bas A Twigt, Alexander H van der Veen, Ruben N van Veen, Jefrey Vermeulen, Dagmar I Vos, Jasper Winkelhagen, J Carel Goslings, Tim Schepers
Importance: Following clean (class I, not contaminated) surgical procedures, the rate of surgical site infection (SSI) should be less than approximately 2%. However, an infection rate of 12.2% has been reported following removal of orthopedic implants used for treatment of fractures below the knee. Objective: To evaluate the effect of a single dose of preoperative antibiotic prophylaxis on the incidence of SSIs following removal of orthopedic implants used for treatment of fractures below the knee...
December 26, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29279383/impact-of-an-historic-underground-gas-well-blowout-on-the-current-methane-chemistry-in-a-shallow-groundwater-system
#20
Gilian Schout, Niels Hartog, S Majid Hassanizadeh, Jasper Griffioen
Blowouts present a small but genuine risk when drilling into the deep subsurface and can have an immediate and significant impact on the surrounding environment. Nevertheless, studies that document their long-term impact are scarce. In 1965, a catastrophic underground blowout occurred during the drilling of a gas well in The Netherlands, which led to the uncontrolled release of large amounts of natural gas from the reservoir to the surface. In this study, the remaining impact on methane chemistry in the overlying aquifers was investigated...
December 26, 2017: Proceedings of the National Academy of Sciences of the United States of America
keyword
keyword
30468
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"