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https://www.readbyqxmd.com/read/28092331/-reply-to-effectiveness-of-autologous-fat-grafting-in-adherent-scars-results-obtained-by-a-comprehensive-scar-evaluation-protocol
#1
Mariëlle E H Jaspers, Esther Middelkoop, Paul P M van Zuijlen
No abstract text is available yet for this article.
January 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28088057/a-systematic-review-of-adult-attachment-and-social-anxiety
#2
REVIEW
Ray P C Manning, Joanne M Dickson, Jasper Palmier-Claus, Alexandra Cunliffe, Peter J Taylor
BACKGROUND: Attachment has been implicated in the development of social anxiety. Our aim was to synthesise the extant literature exploring the role of adult attachment in these disorders. METHOD: Search terms relating to social anxiety and attachment were entered into MEDLINE, PsycINFO and Web of Science. Risk of bias of included studies was assessed using and adapted version of the Agency for Healthcare Research and Quality assessment tool. Eligible studies employed validated social anxiety and attachment assessments in adult clinical and analogue samples...
December 19, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28087426/next-generation-sequencing-of-a-large-gene-panel-in-patients-initially-diagnosed-with-idiopathic-ventricular-fibrillation
#3
Marloes Visser, Dennis Dooijes, Jasper J van der Smagt, Jeroen F van der Heijden, Pieter A Doevendans, Peter Loh, Folkert W Asselbergs, Rutger J Hassink
BACKGROUND: Idiopathic ventricular fibrillation (IVF) is a rare primary cardiac arrhythmia syndrome that is diagnosed in a resuscitated cardiac arrest victim, with documented ventricular fibrillation, in whom no underlying cause is identified after comprehensive clinical evaluation. In some patients causative genetic mutations are detected which facilitate patient treatment and follow-up. The feasibility of next generation sequencing (NGS) has increased with its greater availability and decreasing costs...
January 10, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28080972/towards-a-psychophysics-of-interoceptive-processes-the-measurement-of-heartbeat-detection
#4
REVIEW
Jasper Brener, Christopher Ring
It is difficult to collect objective evidence of interoception. Unlike exteroception, the effective stimuli for interoception are often unknown, and even when identifiable, they are difficult to control experimentally. Furthermore, direct stimulation of the interoceptors is seldom appropriate in human experimentation. Hence, non-invasive behavioural measures of accuracy in heartbeat detection have frequently been adopted to index interoceptive sensitivity. However, there has been little standardization and the two most popular methods for assessing heartbeat detection, heartbeat tracking and two alternative forced choice methods, appear to be biased and of questionable validity...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28079878/a-complete-workflow-for-high-resolution-spectral-stitching-nanoelectrospray-direct-infusion-mass-spectrometry-based-metabolomics-and-lipidomics
#5
Andrew D Southam, Ralf J M Weber, Jasper Engel, Martin R Jones, Mark R Viant
Metabolomic and lipidomic studies measure and discover metabolic and lipid profiles in biological samples, enabling a better understanding of the metabolism of specific biological phenotypes. Accurate biological interpretations require high analytical reproducibility and sensitivity, and standardized and transparent data processing. Here we describe a complete workflow for nanoelectrospray ionization (nESI) direct-infusion mass spectrometry (DIMS) metabolomics and lipidomics. After metabolite and lipid extraction from tissues and biofluids, samples are directly infused into a high-resolution mass spectrometer (e...
February 2016: Nature Protocols
https://www.readbyqxmd.com/read/28078552/pediatric-development-of-bosentan-facilitated-by-modeling-and-simulation
#6
Jochen Zisowsky, Martine Géhin, Andjela Kusic-Pajic, Andreas Krause, Maurice Beghetti, Jasper Dingemanse
BACKGROUND: Bosentan is approved for use in adult patients with pulmonary arterial hypertension. The primary aim of the pharmacokinetic modeling was the provision of a systematic guidance for study design and enhanced understanding of pharmacokinetics across the entire pediatric age range. METHODS: A physiologically based pharmacokinetic model was developed for the pediatric population; starting from an adult model, the effects of body weight, age, and maturation of relevant metabolizing enzymes were incorporated to extrapolate the pharmacokinetics to children...
January 11, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28073949/the-effects-of-feedback-and-incentive-based-insurance-on-driving-behaviours-study-approach-and-protocols
#7
Mark Stevenson, Anthony Harris, Duncan Mortimer, Jasper S Wijnands, Alan Tapp, Frank Peppard, Samantha Buckis
BACKGROUND: Road injury is the leading cause of death for young people, with human error a contributing factor in many crash events. This research is the first experimental study to examine the extent to which direct feedback and incentive-based insurance modifies a driver's behaviour. The study applies in-vehicle telematics and will link the information obtained from the technology directly to personalised safety messaging and personal injury and property damage insurance premiums. METHODS: The study has two stages...
January 10, 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/28073142/cardio-oncology-progress-in-diagnosis-and-treatment-of-cardiac-dysfunction
#8
REVIEW
Jasper Tromp, Lars C Steggink, Dirk J Van Veldhuisen, Jourik A Gietema, Peter van der Meer
No abstract text is available yet for this article.
January 10, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28064165/nutritional-control-of-chronological-aging-and-heterochromatin-in-saccharomyces-cerevisiae
#9
David F McCleary, Jasper Rine
Calorie restriction extends lifespan in organisms as diverse as yeast and mammals through incompletely understood mechanism(s). The role of NAD(+)-dependent deacetylases, known as Sirtuins, in this process, particularly in the yeast S. cerevisiae is controversial. We measured chronological lifespan of wild-type and sir2Δ strains over a higher glucose range than typically used for studying yeast calorie restriction. sir2Δ extended lifespan in high-glucose complete minimal medium, and had little effect in low glucose medium, revealing a partial role for Sir2 in the calorie restriction response under these conditions...
January 6, 2017: Genetics
https://www.readbyqxmd.com/read/28057747/complete-genome-sequence-of-akkermansia-glycaniphila-strain-pytt-a-mucin-degrading-specialist-of-the-reticulated-python-gut
#10
Janneke P Ouwerkerk, Jasper J Koehorst, Peter J Schaap, Jarmo Ritari, Lars Paulin, Clara Belzer, Willem M de Vos
Akkermansia glycaniphila is a novel Akkermansia species that was isolated from the intestine of the reticulated python and shares the capacity to degrade mucin with the human strain Akkermansia muciniphila Muc(T) Here, we report the complete genome sequence of strain Pyt(T) of 3,074,121 bp. The genomic analysis reveals genes for mucin degradation and aerobic respiration.
January 5, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28053389/is-pre-operative-assessment-of-coagulation-profile-with-thrombelastography-teg-useful-in-predicting-venous-thromboembolism-vte-following-orthopaedic-surgery
#11
Apurve Parameswaran, Vignesh P Krishnamoorthy, Anil T Oommen, Anita Jasper, Ravi J Korula, Sukesh C Nair, Pradeep M Poonnoose
INTRODUCTION: Epidemiologic data on the incidence of venous thromboembolism (VTE) in Indian population vary widely. Most studies show that the incidence of VTE is lower in Asian patients than in Western population. Screening tools to identify high-risk patients should enable us to reduce this complication. METHODS: The incidence of VTE in 101 patients who underwent knee or hip arthroplasty, or surgery for hip fractures, without chemoprophylaxis for deep vein thrombosis (DVT) was documented...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28051343/methodological-considerations-when-quantifying-high-intensity-efforts-in-team-sport-using-global-positioning-system-technology
#12
Matthew C Varley, Arne Jaspers, Werner F Helsen, James J Malone
Purpose Sprints and accelerations are popular performance indicators in applied sport. The methods used to define these efforts using athlete tracking technology could affect the number of efforts reported. The study aimed to determine the influence of different techniques and settings for detecting high-intensity efforts using Global Positioning System (GPS) data. Methods Velocity and acceleration data of a professional soccer match was recorded via 10-Hz GPS. Velocity data was filtered using either a median or exponential filter...
January 4, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28049197/venous-air-embolism-during-hysteroscopic-myomectomy-an-analysis-of-7-cases
#13
Cédric Van Dijck, Steffen Rex, Jasper Verguts, Dirk Timmerman, Marc Van de Velde, An Teunkens
Venous air embolism (VAE) is a rare but potentially fatal complication of hysteroscopic myomectomy. The symptoms of VAE range from mild and clinically insignificant to complete cardiovascular collapse during surgery. Anesthesiologists and surgeons should be aware of the clinical characteristics and predisposing factors of this possible adverse event. This report analyzes 7 cases of VAE, which occurred at the University Hospitals Leuven, in patients undergoing hysteroscopic myomectomy from April 2009 to April 2011...
January 4, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28041330/quality-of-life-after-different-surgical-procedures-for-the-treatment-of-spinal-metastases-results-of-a-single-center-prospective-case-series
#14
Godard C W de Ruiter, Claudine O Nogarede, Jasper F C Wolfs, Mark P Arts
OBJECTIVE The performance of surgery for spinal metastases is rapidly increasing. Different surgical procedures, ranging from stabilization alone to stabilization combined with corpectomy, are thereby performed for various indications. Little is known about the impact of these different procedures on patient quality of life (QOL), but this factor is crucial when discussing the various therapeutic options with patients and their families. Thus, the authors of this study investigated the effect of various surgical procedures for spinal metastases on patient QOL...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28034899/comparison-of-the-efficacy-and-safety-of-early-rule-out-pathways-for-acute-myocardial-infarction
#15
Andrew R Chapman, Atul Anand, Jasper Boeddinghaus, Amy V Ferry, Dennis Sandeman, Philip D Adamson, Jack P Andrews, Stephanie Tan, Sheun F Cheng, Michelle D'Souza, Kate Orme, Fiona E Strachan, Thomas Nestelberger, Raphael Twerenbold, Patrick Badertscher, Tobias Reichlin, Alasdair Gray, Anoop S V Shah, Christian Mueller, David E Newby, Nicholas L Mills
BACKGROUND: -High-sensitivity cardiac troponin assays enable myocardial infarction to be ruled out earlier, but the optimal approach is uncertain. We compared the European Society of Cardiology (ESC) rule-out pathway, with a pathway that incorporates lower cardiac troponin concentrations to risk stratify patients. METHODS: -Patients with suspected acute coronary syndrome (n=1,218) underwent high-sensitivity cardiac troponin I measurement at presentation, 3 and 6 or 12 hours...
December 29, 2016: Circulation
https://www.readbyqxmd.com/read/28034846/patent-saphenous-vein-grafts-35-years-post-coronary-artery-bypass-surgery
#16
Georgina Ooues, Jasper Trevelyan
No abstract text is available yet for this article.
January 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28034413/factors-influencing-implementation-success-of-guideline-based-clinical-decision-support-systems-a-systematic-review-and-gaps-analysis
#17
REVIEW
E Kilsdonk, L W Peute, M W M Jaspers
OBJECTIVE: To provide an integrated and differentiated understanding of factors influencing guideline-based CDSS implementation and illustrate the gaps in the current literature. MATERIALS AND METHODS: A systematic literature review and in-depth exploration of factors impeding or facilitating successful implementation of guideline-based CDSS supporting physicians in clinical decision-making was performed. Factors were identified thematically by textual analysis of the included publications and were individually mapped to the human, organization and technology-fit (HOT-fit) framework for evaluating implementations of health information systems...
February 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28029247/enhancing-the-catalytic-activity-of-zn-containing-magnetic-oxides-in-a-methanol-synthesis-identifying-the-key-factors
#18
Nicholas Baird, Jasper W Dittmar, Yaroslav B Losovyj, David Gene Morgan, Barry D Stein, Maren Pink, Nina V Kuchkina, Elena S Serkova, Olga L Lependina, Maxim E Grigoriev, Alexander I Sidorov, Mikhail G Sulman, Zinaida B Shifrina, Lyudmila M Bronstein
A new family of Ni-, Co-, and Cr-doped Zn-containing magnetic oxide nanoparticles (NPs) stabilized by polyphenylquinoxaline (PPQ) and hyperbranched pyridylphenylene polymer (PPP) has been developed. These NPs have been synthesized by thermal decomposition of Zn and doping metal acetylacetonates in the reaction solution of preformed magnetite NPs, resulting in single-crystal NPs with spinel structure. For the PPQ-capped NPs, it was demonstrated that all three types of metal species (Fe, Zn, and a doping metal) reside within the same NPs, the surface of which is enriched with Zn and a doping metal, while the deeper layers are enriched with Fe...
January 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28028771/modeling-the-effect-of-the-selective-s1p1-receptor-modulator-ponesimod-on-subsets-of-blood-lymphocytes
#19
Dominik Lott, Andreas Krause, Christian A Seemayer, Daniel S Strasser, Jasper Dingemanse, Thorsten Lehr
PURPOSE: This analysis aimed at describing the effect of the selective sphingosine-1-phosphate receptor 1 modulator ponesimod on lymphocyte subsets in peripheral blood. As the involvement of different lymphocyte subsets varies among different autoimmune diseases, characterizing the effect of ponesimod on these may be beneficial in better understanding treatment effects. METHODS: Three phase 1 clinical studies in healthy human subjects were pooled. Non-linear mixed-effects modeling techniques were used to study the effect of ponesimod on lymphocyte subsets such as B cells, T helper cells, T cytotoxic cells, and natural killer cells in a qualitative and quantitative manner...
December 27, 2016: Pharmaceutical Research
https://www.readbyqxmd.com/read/28027010/attending-to-timely-contingencies-promoting-physical-activity-uptake-among-adults-with-serious-mental-illness-with-an-exercise-for-mood-vs-an-exercise-for-fitness-prescription
#20
Bridget A Hearon, Courtney Beard, Lynne M Kopeski, Jasper A J Smits, Michael W Otto, Thröstur Björgvinsson
Despite evidence for both physical and mental health benefits achieved through regular exercise, most Americans fail to meet minimum recommendations. Altering the behavioral contingency from a focus on long-term health benefits to immediate mood benefits represents a novel method for exercise promotion. The current study examined a single-session exercise-for-mood intervention against two time-matched comparison conditions in 152 patients with serious mental illness attending a partial hospital program, a population marked by significant health disparities...
December 27, 2016: Behavioral Medicine
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