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https://www.readbyqxmd.com/read/29042406/what-data-sources-do-ophthalmologists-trust
#1
William C Stewart, Jeanette A Stewart, Lindsay A Nelson
To survey ophthalmologists regarding sources they trust when incorporating new medical knowledge into their practice. The survey was distributed primarily to US-based ophthalmologists. Questions were derived based on the lead author's research experience from congresses and discussions and from mentions in the medical literature. In total, 77 physicians completed the survey of 1886 sent (4% response rate). Regarding study design, physicians preferred a well-controlled, randomised, double-masked trial (99%) with multicentred investigational site across a wide geographical area (80%)...
October 17, 2017: Evidence-based Medicine
https://www.readbyqxmd.com/read/28960119/the-use-of-sports-imagery-and-terminology-on-cigarette-packs-from-fourteen-countries
#2
Cerise Kleb, Kevin Welding, Joanna E Cohen, Katherine C Smith
BACKGROUND: Tobacco companies have historically associated their products with sports through event sponsorship and sports-themed advertising campaigns. Such linkages serve to enhance brand image by connecting cigarette brands to ideals associated with sports such as strength, individual accomplishment, and a healthy body. Public health policy progress has created restrictions for tobacco sponsorship and restricted traditional advertising avenues for tobacco products. Nonetheless, the pack itself remains as a mechanism by which to link cigarettes to sports and sporting prowess...
September 29, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28953741/trends-frequency-and-nature-of-surgeon-reported-conflicts-of-interest-in-plastic-surgery
#3
REVIEW
Joseph Lopez, Leila Musavi, Amy Quan, Nicholas Calotta, Ilona Juan, Angela Park, Anthony P Tufaro, James W May, Amir H Dorafshar
BACKGROUND: The purpose of this study was to identify types and trends in industry sponsorship of plastic surgery research since the establishment of conflict-of-interest reporting policies in plastic surgery. METHODS: The authors analyzed the frequency and types of self-reported conflicts of interest in the plastic surgery literature since the adoption of reporting policies in 2007. All original articles that met the authors' inclusion criteria and were published in the following three journals from 2008 to 2013 were included: Annals of Plastic Surgery, Plastic and Reconstructive Surgery, and Journal of Plastic, Reconstructive & Aesthetic Surgery...
October 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28893095/efficacy-of-antidepressants-bias-in-randomized-clinical-trials-and-related-issues
#4
Sheng-Min Wang, Changsu Han, Soo-Jung Lee, Tae-Youn Jun, Ashwin A Patkar, Prakash S Masand, Chi-Un Pae
Countless antidepressant randomized trials were conducted and showed statistically significant benefits of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) over placebo. Meanwhile, critics are increasing regarding the efficacy of antidepressants in the treatment of MDD because at least a proportion of clinical trials could be hampered by various biases. In contrast, number of failed trials is increasing in the recent years which have made developing psychiatric medications progressively more time-consuming and expensive...
September 14, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28859920/sponsoring-surgeons-an-investigation-on-the-influence-of-the-da-vinci-robot
#5
Cory N Criss, Samir K Gadepalli
INTRODUCTION: The integrity of the medical literature about robotic surgery remains unclear despite wide-spread adoption. We sought to determine if payment from Intuitive Surgical Incorporated (ISI) affected quality of the research produced by surgeons. METHODS: Publicly available financial data from the CMS website regarding the top-20 earners from ISI for 2015 was gathered. Studies conducted by these surgeons were identified using PubMed. Inclusion criteria consisted of publications about the da Vinci(®) robot on patient outcomes...
August 26, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28827228/a-content-analysis-of-the-representation-of-statins-in-the-british-newsprint-media
#6
Julia Chisnell, Tom Marshall, Chris Hyde, Zhivko Zhelev, Lora E Fleming
OBJECTIVE: This study reviewed the news media coverage of statins, seeking to identify specific trends or differences in viewpoint between media outlets and examine common themes. DESIGN: The study is a content analysis of the frequency and content of the reporting of statins in a selection of the British newsprint media. It involved an assessment of the number, timing and thematic content of articles followed by a discourse analysis examining the underlying narratives...
August 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28816610/tobacco-control-law-implementation-in-a-middle-income-country-transnational-tobacco-control-network-overcoming-tobacco-industry-opposition-in-colombia
#7
Randy Uang, Eric Crosbie, Stanton A Glantz
The objective of this paper is to examine the implementation of Colombia's tobacco control law. Methods involved are triangulated government legislation, news sources, and interviews with policy-makers and health advocates in Colombia. Colombia, a middle-income country, passed a tobacco control law in 2009 that included a prohibition on tobacco advertising, promotion, and sponsorship; and required pictorial health warning labels, ingredients disclosure, and a prohibition on individual cigarette sales. Tobacco companies challenged the implementation through litigation, tested government enforcement of advertising provisions and regulations on ingredients disclosure, and lobbied local governments to deprioritise policy responses to single cigarette sales...
August 17, 2017: Global Public Health
https://www.readbyqxmd.com/read/28703260/-publish-amp-perish-research-on-research-and-researchers
#8
J K Tijdink
In the last years many people have questioned the reliability of research results and the societal relevance of much of today's clinical research; they are critical too about the current publication culture in which scientists are judged according to the number of articles they have published, impact factors and citations.<br/> AIM: To make a close study of the publication culture that now prevails in the Dutch biomedical sciences. <br/> METHOD: Discussion of results described in the thesis entitled 'Publish and Perish; research on research and researchers'...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/28667226/a-cross-sectional-analysis-of-pharmaceutical-industry-funded-events-for-health-professionals-in-australia
#9
Alice Fabbri, Quinn Grundy, Barbara Mintzes, Swestika Swandari, Ray Moynihan, Emily Walkom, Lisa A Bero
OBJECTIVES: To analyse patterns and characteristics of pharmaceutical industry sponsorship of events for Australian health professionals and to understand the implications of recent changes in transparency provisions that no longer require reporting of payments for food and beverages. DESIGN: Cross-sectional analysis. PARTICIPANTS AND SETTING: 301 publicly available company transparency reports downloaded from the website of Medicines Australia, the pharmaceutical industry trade association, covering the period from October 2011 to September 2015...
June 30, 2017: BMJ Open
https://www.readbyqxmd.com/read/28631099/discontinuation-of-pharmacological-treatment-of-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-meta-analysis-of-63-studies-enrolling-11-788-patients
#10
M Riera, X Castells, A Tobias, R Cunill, L Blanco, D Capellà
BACKGROUND: The risk-benefit balance of pharmacological treatment for children and adolescents with ADHD and the factors that moderate this relationship are unclear. METHODS: A systematic review and meta-analysis of randomised, placebo-controlled clinical trials (RPCCTs) investigating the efficacy of pharmacological treatment in children or adolescents with ADHD was carried out. Meta-analysis of treatment discontinuation, clinician-, parent- and teacher-rated efficacy and adverse events was performed...
June 19, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28595992/-food-industry-funding-and-epidemiologic-research-in-public-health-nutrition
#11
Eva María Navarrete-Muñoz, Adonina Tardón, Dora Romaguera, Miguel Ángel Martínez-González, Jesús Vioque
The interests of the food industry to fund nutrition and health research are not limited to promoting scientific advances. Recently, several systematic reviews conducted about the effect of sugar-sweetened beverages and health outcomes have shown some biased conclusions in studies that acknowledge industry sponsorship. In this context, the Nutrition Working Group of the Spanish Epidemiology Society presented a scientific session entitled Food industry and epidemiologic research at its annual meeting. In a round table, four experts in nutrition research presented their points of view about whether the food industry should fund nutrition-related research and the related potential conflicts of interest of the food industry...
June 5, 2017: Gaceta Sanitaria
https://www.readbyqxmd.com/read/28594535/collaborative-orthopaedic-research-between-and-within-institutions
#12
Brian R Wolf, Nikhil N Verma, Kurt P Spindler, Rick W Wright
Collaborative research is common in many medical disciplines; however, the field of orthopaedics has been relatively slow to adopt this type of research approach. Collaborative research efforts can occur between multiple institutions and, in some instances, may benefit from subspecialty society sponsorship. Collaborative research efforts between several research spheres within a single institution also can be advantageous. Collaborative research has many benefits, including a larger number of patients in studies, more power in the research, and better generalizability...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28591792/corporate-sponsorship-of-physical-activity-promotion-programmes-part-of-the-solution-or-part-of-the-problem
#13
B Jane, K Gibson
Background: Parklives is a programme intended to raise levels of physical activity across the UK, funded by Coca-Cola GB and delivered in association with Local Authorities and other organizations. Such public-private partnerships have been advocated by many however critics suggest that the conflict between stakeholder motives is too great. Methods: This study conducted a content analysis of twitter content related to the ParkLives physical activity programme. Images and text were analysed from two separate weeks, one from the school vacation period and one during school term time...
June 7, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28573138/lurasidone-in-the-treatment-of-bipolar-depression-systematic-review-of-systematic-reviews
#14
REVIEW
Michele Fornaro, Domenico De Berardis, Giampaolo Perna, Marco Solmi, Nicola Veronese, Laura Orsolini, Elisabetta Filomena Buonaguro, Felice Iasevoli, Cristiano André Köhler, André Ferrer Carvalho, Andrea de Bartolomeis
INTRODUCTION: A burgeoning number of systematic reviews considering lurasidone in the treatment of bipolar depression have occurred since its Food and Drug Administration extended approval in 2013. While a paucity of available quantitative evidence still precludes preliminary meta-analysis on the matter, the present quality assessment of systematic review of systematic reviews, nonetheless, aims at highlighting current essential information on the topic. METHODS: Both published and unpublished systematic reviews about lurasidone mono- or adjunctive therapy in the treatment of bipolar depression were searched by two independent authors inquiring PubMed/Cochrane/Embase/Scopus from inception until October 2016...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28541090/sixty-years-of-placebo-controlled-antipsychotic-drug-trials-in-acute-schizophrenia-systematic-review-bayesian-meta-analysis-and-meta-regression-of-efficacy-predictors
#15
REVIEW
Stefan Leucht, Claudia Leucht, Maximilian Huhn, Anna Chaimani, Dimitris Mavridis, Bartosz Helfer, Myrto Samara, Matteo Rabaioli, Susanne Bächer, Andrea Cipriani, John R Geddes, Georgia Salanti, John M Davis
OBJECTIVE: Antipsychotic drug efficacy may have decreased over recent decades. The authors present a meta-analysis of all placebo-controlled trials in patients with acute exacerbations of schizophrenia, and they investigate which trial characteristics have changed over the years and which are moderators of drug-placebo efficacy differences. METHOD: The search included multiple electronic databases. The outcomes were overall efficacy (primary outcome); responder and dropout rates; positive, negative, and depressive symptoms; quality of life; functioning; and major side effects...
October 1, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/28480479/historical-roots-of-international-biomedical-and-health-informatics-the-road-to-ifip-tc4-and-imia-through-cybernetic-medicine-and-the-elsinore-meetings
#16
C A Kulikowski
Background: It is 50 years since the International Federation of Information Processing (IFIP) Societies approved the formation of a new Technical Committee (TC) 4 on Medical Information Processing under the leadership of Professor Francois Grémy, which was the direct precursor of the International Medical Informatics Association (IMIA). Objectives: The goals of this paper are to give a very brief overview of early international developments leading to informatics in medicine, with the origins of the applications of computers to medicine in the USA and Europe, and two meetings - of the International Society of Cybernetic Medicine, and the Elsinore Meetings on Hospital Information Systems-that took place in 1966...
August 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28473746/practices-related-to-tobacco-sale-promotion-and-protection-from-tobacco-smoke-exposure-in-restaurants-and-bars-in-kampala-before-implementation-of-the-uganda-tobacco-control-act-2015
#17
Steven Ndugwa Kabwama, Daniel Kadobera, Sheila Ndyanabangi, Kellen Namusisi Nyamurungi, Shannon Gravely, Lindsay Robertson, David Guwatudde
BACKGROUND: The Word Health Organization's Framework Convention on Tobacco Control calls on parties to implement evidenced-based tobacco control policies, which includes Article 8 (protect the public from exposure to tobacco smoke), and Article 13 (tobacco advertising, promotion and sponsorship (TAPS)). In 2015, Uganda passed the Tobacco Control Act 2015 which includes a comprehensive ban on smoking in all public places and on all forms of TAPS. Prior to implementation, we sought to assess practices related to protection of the public from tobacco smoke exposure, limiting access to tobacco products and TAPS in restaurants and bars in Kampala City to inform implementation of the new law...
2017: Tobacco Induced Diseases
https://www.readbyqxmd.com/read/28412315/reporting-compliance-of-stroke-trials-cross-sectional-analysis
#18
Konark Malhotra, Appaji Rayi, Monica Khunger, Stephanie Thompson, David S Liebeskind
BACKGROUND: The FDA mandates timely reporting of all clinical trials conducted in the United States. However, often the results are not reported in a timely manner, resulting in wastage of finite resources. We assessed the reporting of results of completed stroke trials and compared the reporting trends between U.S. and non-U.S. stroke trials. METHODS: We assessed consecutive clinical stroke trials registered as completed in ClinicalTrials.gov between January 1, 2008 and January 1, 2015...
April 13, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28410086/premature-discontinuation-of-pediatric-randomized-controlled-trials-a-retrospective-cohort-study
#19
Stefan Schandelmaier, Yuki Tomonaga, Dirk Bassler, Joerg J Meerpohl, Erik von Elm, John J You, Anette Bluemle, Francois Lamontagne, Ramon Saccilotto, Alain Amstutz, Theresa Bengough, Mihaela Stegert, Kelechi K Olu, Kari A O Tikkinen, Ignacio Neumann, Alonso Carrasco-Labra, Markus Faulhaber, Sohail M Mulla, Dominik Mertz, Elie A Akl, Xin Sun, Jason W Busse, Ignacio Ferreira-González, Alain Nordmann, Viktoria Gloy, Heike Raatz, Lorenzo Moja, Rachel Rosenthal, Shanil Ebrahim, Per O Vandvik, Bradley C Johnston, Martin A Walter, Bernard Burnand, Matthias Schwenkglenks, Lars G Hemkens, Gordon Guyatt, Heiner C Bucher, Benjamin Kasenda, Matthias Briel
OBJECTIVES: To determine the proportion of pediatric randomized controlled trials (RCTs) that are prematurely discontinued, examine the reasons for discontinuation, and compare the risk for recruitment failure in pediatric and adult RCTs. STUDY DESIGN: A retrospective cohort study of RCTs approved by 1 of 6 Research Ethics Committees (RECs) in Switzerland, Germany, and Canada between 2000 and 2003. We recorded trial characteristics, trial discontinuation, and reasons for discontinuation from protocols, corresponding publications, REC files, and a survey of trialists...
May 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28333580/air-quality-measurements-from-rubber-bands-to-tapping-the-rainbow
#20
REVIEW
George M Hidy, Peter K Mueller, Samuel L Altshuler, Judith C Chow, John G Watson
It is axiomatic that good measurements are integral to good public policy for environmental protection. The generalized term for "measurements" includes sampling and quantitation, data integrity, documentation, network design, sponsorship, operations, archiving, and accessing for applications. Each of these components has evolved and advanced over the last 200 years as knowledge of atmospheric chemistry and physics has matured. Air quality was first detected by what people could see and smell in contaminated air...
June 2017: Journal of the Air & Waste Management Association
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