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https://www.readbyqxmd.com/read/29454133/prevalence-and-risk-factors-for-neural-axis-anomalies-in-idiopathic-scoliosis-a-systematic-review
#1
REVIEW
Johan L Heemskerk, Moyo C Kruyt, Dino Colo, René M Castelein, Diederik H R Kempen
BACKGROUND: There is ongoing controversy about the routine use of magnetic resonance imaging (MRI) preoperatively in patients with presumed idiopathic scoliosis (IS). Routine MRI can help identify possible causes for the deformity and detect anomalies which could complicate deformity surgery. However, routine MRI increases health care costs significantly and may reveal mild variations from normal without clinical relevance, that can still lead to anxiety and influence decision making...
February 14, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29449737/unexpected-cause-for-duodenal-obstruction-brunner-s-gland-hyperplasia
#2
B Dhouha, L Ahlem, B S Sana, B Saadia, M R Sabeh
Brunner's gland hyperplasia is a rare benign lesion arising from the duodenum. It is often an incidental finding on endoscopy with the majority of patients being asymptomatic. It may also present with various symptoms depending on location and tumor size, such as gastrointestinal bleeding, obstruction and abdominal pain. We report an unusual case of large Brunner's gland hyperplasia in 72-years old man, admitted to hospital for epigastric pain, recurrent vomiting and significantly weight loss. Upper endoscopy showed an obstructive submucosis tumour of the bulb...
December 2017: Pathologica
https://www.readbyqxmd.com/read/29445421/evidence-for-a-pre-malignant-cell-line-in-a-skin-biopsy-from-a-patient-with-nijmegen-breakage-syndrome
#3
Raneem Habib, Heidemarie Neitzel, Aurelie Ernst, John K L Wong, Bozenna Goryluk-Kozakiewicz, Antje Gerlach, Ilja Demuth, Karl Sperling, Krystyna Chrzanowska
Background: Nijmegen breakage syndrome is an autosomal recessive disorder characterized by microcephaly, immunodeficiency, hypersensitivity to X-irradiation, and a high predisposition to cancer. Nibrin, the product of the NBN gene, is part of the MRE11/RAD50 (MRN) complex that is involved in the repair of DNA double strand breaks (DSBs), and plays a critical role in the processing of DSBs in immune gene rearrangements, telomere maintenance, and meiotic recombination. NBS skin fibroblasts grow slowly in culture and enter early into senescence...
2018: Molecular Cytogenetics
https://www.readbyqxmd.com/read/29443763/epibulbar-complex-cartilaginous-choristoma-a-distinctive-clinicopathological-case-series-and-literature-review
#4
Zongduan Zhang, Zhengwei Yang, Qintuo Pan, Xiaoyi Qin, Yuxuan Deng, Yuehong Cao
To newly describe the clinical and histopathological characteristics of epibulbar complex cartilaginous choristoma incidentally observed in a series of pterygium excision patients.Noncomparative case series with chart review of 8 patients.During a 4-year period, we identified 8 cases of conventional unilateral nasal subpterygial cartilaginous choristoma in 1799 pterygium patients and analyzed their clinicopathological features. The incidence rate of this entity is 0.44% in pterygium patients. All of the cartilaginous choristomas were buried deep in the caruncle, covered by the pterygium, and embedded in tenon facia tissue...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443753/intense-18f-fdg-activity-in-aortoiliac-bypass-graft-mimicking-infection-a-case-report
#5
Minkyung Lee, Jeong Seon Ryu, Chang Hae Suh, In Young Hyun
RATIONALE: F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) has the potential to become an important imaging tool for the diagnosis of suspected aortoiliac bypass graft infection (AGI). PATIENT CONCERNS: A 76-year-old man presented with incidental findings of intense F-FDG activity in previous operation site of aortobiiliac bypass graft in the initial staging of small cell lung cancer (SCLC). DIAGNOSES: Based on F-FDG PET/CT examination, preliminary differential diagnosis was AGI...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443514/environmentally-persistent-free-radicals-insights-on-a-new-class-of-pollutants
#6
Eric Warren Vejerano, Guiying Rao, Lavrent Khachatryan, Stephania A Cormier, Slawomir M Lomnicki
Environmentally persistent free radicals, EPFRs, exist in significant concentration in atmospheric particulate matter (PM). EPFRs are primarily emitted from combustion and thermal processing of organic materials, in which the organic combustion by-products interact with transition metal-containing particles to form a free radical-particle pollutant. While the existence of persistent free radicals in combustion has been known for over half-a-century, only recently that their presence in environmental matrices and health effects have started significant research, but still in its infancy...
February 14, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29442349/18f-fdg-avid-sclerosing-angiomatoid-nodular-transformation-sant-of-spleen-on-pet-ct-a-rare-mimicker-of-metastasis
#7
Punit Sharma
Sclerosing Angiomatoid Nodular Transformation (SANT) is a rare benign vascular tumor of spleen. It consists of multiple angiomatoid nodules surrounded by dense fibrous tissue that often coalesces centrally to form a scar, which is considered to be a characteristic feature. These are usually asymptomatic and incidentally detected on imaging for other underlying pathology. SANTs can be 18F-Fluorodeoxyglucose (18F-FDG) avid on positron emission tomography-computed tomography (PET-CT) and thus can lead to false positive finding in oncological patients...
2018: Nuclear Medicine Review. Central & Eastern Europe
https://www.readbyqxmd.com/read/29441443/double-chambered-left-ventricle-a-heart-within-a-heart
#8
John D Gilbert, Roger W Byard
A 20-year-old previously well man drowned after performing a back-flip off a bridge into a river. At autopsy no significant injuries or organic illness were identified. An unusual incidental finding was a double chambered left ventricle, or so-called "heart within a heart", with the left ventricle subdivided into two separate chambers by a muscular septum. Awareness of this entity in forensic casework is important as this anomaly, despite its dramatic appearance, is not associated with anomalous conduction tracts or arrhythmogenic conditions, and so is usually a completely incidental finding at autopsy...
February 13, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29441326/a-rare-case-of-primary-intrapulmonary-neurilemmoma-diagnosed-in-a-43-year-old-asymptomatic-man-with-a-well-defined-intrapulmonary-mass
#9
Serafeim Chrysikos, Maria Kaponi, Christina Triantafillidou, Theodoros Karampitsakos, Argyrios Tzouvelekis, Maria Anyfanti, Konstantinos Marossis, Marios Konstantinou, Rodoula Tringidou, Demosthenes Bouros, Katerina Dimakou
Neurilemmoma (NL), also termed schwannoma, presents as a well-circumscribed and encapsulated mass in the human body and is almost always solitary. CT scan of a patient with NL shows a round, ovoid, or lobulated well-demarcated solid mass of soft tissue density. Primary intrathoracic neurogenic tumors location varies. However, the development of such tumors is by far more common in the costovertebral angle of the posterior mediastinum. Here, we report a rare case of a 43-year-old patient, never smoker and previously healthy, who presented with a mass adjacent to the right pulmonary hilum...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29440429/locus-coeruleus-integrity-in-old-age-is-selectively-related-to-memories-linked-with-salient-negative-events
#10
Dorothea Hämmerer, Martina F Callaghan, Alexandra Hopkins, Julian Kosciessa, Matthew Betts, Arturo Cardenas-Blanco, Martin Kanowski, Nikolaus Weiskopf, Peter Dayan, Raymond J Dolan, Emrah Düzel
The locus coeruleus (LC) is the principal origin of noradrenaline in the brain. LC integrity varies considerably across healthy older individuals, and is suggested to contribute to altered cognitive functions in aging. Here we test this hypothesis using an incidental memory task that is known to be susceptible to noradrenergic modulation. We used MRI neuromelanin (NM) imaging to assess LC structural integrity and pupillometry as a putative index of LC activation in both younger and older adults. We show that older adults with reduced structural LC integrity show poorer subsequent memory...
February 12, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29440337/pulmonary-nodules-as-incidental-findings
#11
Michael Simon, Katherine Zukotynski, David M Naeger
No abstract text is available yet for this article.
February 12, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29437720/uterine-fibroid-or-ovarian-fibroma-importance-of-comprehensive-preoperative-consent-taking-to-include-unexpected-findings-with-management-implications
#12
Lee Koon Kwek, Wei-Wei Wee-Stekly, Su Min Bernard Chern
A 35-year-old woman presented with an abdominal mass found incidentally on an ultrasound scan. On examination, the uterus was mobile and 14 weeks in size. Further imaging showed a large subserosal pedunculated fibroid, and she was counselled for laparoscopic myomectomy, morcellation in a bag, kept in open view. Intraoperatively, the mass was noted to be arising from the right ovarian ligament instead of the uterus, and decision was made to convert to open surgery. This case highlights important issues of consent-taking preoperatively and critical points to note regarding change in operative consent intraoperatively...
February 7, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29434686/pulmonary-alveolar-microlithiasis-a-case-report-and-review-of-the-literature
#13
Xu-Dong Zhang, Jin-Ming Gao, Jin-Mei Luo, Yu Zhao
Pulmonary alveolar microlithiasis (PAM) is a rare autosomal recessive disease characterized by the formation of calcium phosphate microliths in the alveoli. Mutations in the gene encoding the solute carrier family 34 member 2 gene are considered to be involved in the pathogenesis of PAM. Although PAM can develop in children, the majority of patients with PAM are diagnosed in adulthood due to the slow progressive nature of the disease within the lungs. In childhood, the majority of patients with PAM are asymptomatic and changes in the lung parenchyma are usually identified incidentally...
January 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29434162/bradycardia-is-a-specific-phenotype-of-catecholaminergic-polymorphic-ventricular-tachycardia-induced-by-ryr2-mutations
#14
Kazuaki Miyata, Seiko Ohno, Hideki Itoh, Minoru Horie
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal inherited disease characterized by ventricular arrhythmias induced by physical exercise or emotional stress. The major cause of CPVT is mutations in RYR2, which encodes the cardiac ryanodine receptor channel. Recent advances in sequencing technology have yielded incidental findings of RYR2 variants in other cardiac diseases. Analyzing the characteristics of RYR2 variants related to CPVT will be useful for differentiation from those related to other cardiac diseases...
February 9, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29434022/fifteen-minute-consultation-the-child-with-an-incidental-finding-of-elevated-aminotransferases
#15
Robert Hegarty, Anil Dhawan
It is not unusual to encounter abnormal liver enzyme levels on routine blood tests. When the abnormal elevation in aminotransferases persist, they require prompt and appropriate investigations as liver diseases in children are often insidious in onset and clinically silent. This article aims to provide (1) an explanation to the aetiologies of elevated aminotransferases; (2) an investigational approach to these children and (3) an insight into further investigations performed at a liver centre.
February 6, 2018: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/29433866/management-of-nonparasitic-splenic-cysts-in-children
#16
Jenine Hassoun, Gezzer Ortega, Lorrie S Burkhalter, Shellie Josephs, Faisal G Qureshi
BACKGROUND: The management of nonparasitic splenic cysts in children is unclear. Options include observation, cystectomy, partial or total splenectomy and percutaneous aspiration with and without sclerotherapy. The aim of this study is to assess the outcomes of these interventions at a children's hospital. MATERIALS AND METHODS: A retrospective review of patients aged <18 y with splenic cysts over 7 y was performed. Demographics, mode of intervention, and outcome data were collected...
March 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29433744/chemotherapy-induced-response-of-liver-hemangiomas-in-a-patient-with-a-germ-cell-tumor-a-case-report
#17
N Arévalo, R Méndez, A Manzano
Liver hemangiomas are the most common benign primary tumors of the liver. Due to their high prevalence, incidental finding of hemangiomas during radiological workup of oncologic patients is not uncommon. We present the case of a patient diagnosed of an ovarian immature teratoma and hepatic lesions with typical radiological appearance of hemangiomas that decreased in size during adjuvant chemotherapy with BEP regimen (cisplatin, etoposide and bleomycin). Chemotherapy-induced shrinkage of hepatic hemangiomas can mimic the response of liver metastases to chemotherapy and may induce erroneous interpretations...
February 9, 2018: Radiología
https://www.readbyqxmd.com/read/29433494/incidental-finding-of-large-pneumothorax-on-cardiac-mr-scan
#18
J P M Andrews, G McKillop, M R Dweck
BACKGROUND: We believe this is the first case report of a pneumothorax being identified using cardiac magnetic resonance imaging. This case also illustrates the haemodynamic effect a large pneumothorax can have on right ventricular filling in diastole. CASE PRESENTATION: A 26-year-old attended for an interval follow up Cardiac Magnetic Resonance (CMR) of his thoracic aorta after a thoracic co-arctation repair aged 3. He was found to have an incidental large pneumothorax by the reporting cardiology fellow which was confirmed by the on-call radiologist...
February 12, 2018: BMC Medical Imaging
https://www.readbyqxmd.com/read/29432343/clinical-impact-of-radioguided-localization-in-the-treatment-of-solitary-pulmonary-nodule-a-20-year-retrospective-analysis
#19
Gianpiero Manca, Federico Davini, Elisa Tardelli, Annalisa De Liperi, Fabio Falaschi, Franca Melfi, Patrick M Colletti, Domenico Rubello, Duccio Volterrani, Giuseppe Boni
PURPOSE: Incidental solitary pulmonary nodules (SPNs) have become an increasingly common CT finding worldwide. Although there are currently many imaging strategies for evaluating SPNs, the differential diagnosis and management of SPNs remains complex because of overlap between benign and malignant processes. Moreover, transbronchial or percutaneous CT-guided biopsies do not always allow definitive diagnoses. In such cases, video-assisted thoracic surgery (VATS) has become the preferred surgical procedure for diagnosis and, in selected cases, for treatment of indeterminate SPNs...
February 9, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29432275/corr-insights%C3%A2-what-is-the-clinical-importance-of-incidental-findings-on-staging-ct-scans-in-patients-with-sarcoma
#20
Jonathan A Forsberg
No abstract text is available yet for this article.
February 8, 2018: Clinical Orthopaedics and related Research
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