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https://www.readbyqxmd.com/read/27790436/surgical-site-infection-by-methicillin-resistant-staphylococcus-aureus-on-decline
#1
Susmita Bhattacharya, Kuhu Pal, Sonia Jain, Shiv Sekhar Chatterjee, Jayashree Konar
INTRODUCTION: Surgical Site Infection (SSI) is the most common healthcare associated infection that could be averted by antibiotics prophylaxis against the probable offending organisms. As Staphylococcus aureus has been playing a substantial role in the aetiology of SSIs, Methicillin Resistant Staphylococcus aureus (MRSA) happens to be a problem while dealing with the postoperative wound infection. AIM: To determine the prevalence of SSI caused by MRSA and the antibiotic sensitivity pattern of MRSA...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27314033/newly-developed-topical-cefotaxime-sodium-hydrogels-antibacterial-activity-and-in-vivo-evaluation
#2
Azza S Zakaria, Samar A Afifi, Kadria A Elkhodairy
In an attempt to reach better treatment of skin infections, gel formulations containing Cefotaxime (CTX) were prepared. The gel was formulated using Carbopol 934 (C934), Hydroxypropyl Methylcellulose 4000 (HPMC 4000), Carboxymethylcellulose Sodium (Na CMC), Pectin (PEC), Xanthan Gum (XG), or Guar Gum (GG). Thirteen different formulas were prepared and characterized physically in terms of color, syneresis, spreadability, pH, drug content, and rheological properties. Drug-excipients compatibility studies were confirmed by FTIR and then in vitro drug release study was conducted...
2016: BioMed Research International
https://www.readbyqxmd.com/read/26938214/a-randomised-placebo-controlled-trial-of-oral-and-topical-antibiotics-for-children-with-clinically-infected-eczema-in-the-community-the-children-with-eczema-antibiotic-management-cream-study
#3
Nick A Francis, Matthew J Ridd, Emma Thomas-Jones, Victoria Shepherd, Christopher C Butler, Kerenza Hood, Chao Huang, Katy Addison, Mirella Longo, Charis Marwick, Mandy Wootton, Robin Howe, Amanda Roberts, Mohammed Inaam-ul Haq, Vishnu Madhok, Frank Sullivan
BACKGROUND: Secondary skin infection is common during eczema exacerbations and many children are treated with antibiotics when this is suspected, although there is little high-quality evidence to justify this practice. OBJECTIVE: To determine the clinical effectiveness of oral and topical antibiotics, in addition to standard treatment with emollients and topical corticosteroids, in children with clinically infected eczema. DESIGN: Multicentre randomised, double-blind, placebo-controlled trial...
March 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/26259746/-axillary-hidrosadenitis-due-to-leishmania-case-report-and-literature-review
#4
Ana Alberca-Páramo, Esther Pilar García-Santos, Susana Sánchez-García, Francisco Javier Ruescas-García, José Luis Bertelli-Puche, Jesús Martín-Fernández
BACKGROUND: Hidradenitis is a disorder where abscesses appear after the infection of the apocrine sweat glands. It is located normally in the axillae, groin, perineal region, and the scalp. CLINICAL CASE: A 37 year old male was referred by his GP to the General Surgery Department with axillary hidradenitis which had evolved over the years. The physical examination shows signs of hidradenitis in both axillae, with a noticeable suppurative hidradenitis in the right armpit...
May 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/25002017/molecular-epidemiology-of-nasal-isolates-of-methicillin-resistant-staphylococcus-aureus-from-jordan
#5
Amin A Aqel, Hamed M Alzoubi, Anna Vickers, Bruno Pichon, Angela M Kearns
Asymptomatic carriage of methicillin-resistant Staphylococcus aureus (MRSA) can predispose the host to a wide range of infections. To inform public health strategies, this study sought to determine the prevalence and the phenotypic and genotypic characteristics of MRSA from nasal swabs of health care workers (HCWs) and other healthy individuals in Jordan. Overall, 716 nasal swabs were collected from 297 HCWs, 141 adults and 278 children in the community. MRSA was recovered from 56 (7.8%) nasal swabs, which represented carriage rates of 10...
January 2015: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/24813848/erosive-pustular-dermatosis-of-the-scalp-treated-with-0-1-mometasone-furoate-cream
#6
Marek Jankowski, Ewa Skrzeczko-Kwela, Rafał Czajkowski
No abstract text is available yet for this article.
2014: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/22777230/combined-antibiotic-corticosteroid-cream-in-the-empirical-treatment-of-moderate-to-severe-eczema-friend-or-foe
#7
Kam Lun Hon, Shuxin Susan Wang, Kenneth K C Lee, Vivian W Y Lee, Ting Fan Leung, Margaret Ip
BACKGROUND: Eczema is a common atopic disease associated with pruritus, sleep disturbance, and impaired quality of life. Staphylococcus aureus colonization/infection is important in its pathophysiology. AIM: To evaluate the prevalence of S aureus colonization/infection and the efficacy and acceptability of a combined antibiotic/corticosteroid cream in the empirical treatment of eczema. METHODS: Consecutive patients with moderate to severe eczema were recruited...
July 2012: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/21596221/first-identification-of-methicillin-resistant-staphylococcus-aureus-mlst-types-st5-and-st45-and-sccmec-types-iv-and-vt-by-multiplex-pcr-during-an-outbreak-in-a-respiratory-care-ward-in-central-taiwan
#8
Yuan-Ti Lee, Ding-Bang Lin, Wei-Yao Wang, Shih-Ming Tsao, Su-Fang Yu, Miao-Ju Wei, Shun-Fa Yang, Min-Chi Lu, Hui-Ling Chiou, Shiuan-Chih Chen, Meng-Chih Lee
We used molecular typing methods to investigate an outbreak of methicillin-resistant Staphylococcus aureus (MRSA) infections in a respiratory care ward in Taiwan. From March to June 2006, the incidence of MRSA infection increased 3.75-fold. The overall carrier rates among the health care workers (HCWs) were 31.3% (total S. aureus), 16.4% (MRSA), and 14.9% (methicillin-sensitive SA, MSSA). Pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST), antibiograms derived from susceptibility testing of MRSA isolates, and multiplex polymerase chain reaction (PCR) provided strong epidemiologic and microbiologic evidence that the outbreak of MRSA infections at our hospital was linked to the same PFGE pulsotype A SCCmec type II, pvl-negative, MLST ST5 strain of MRSA isolated from seven HCWs and five patients...
June 2011: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/20327154/fucidin-a-new-antibiotic
#9
(no author information available yet)
No abstract text is available yet for this article.
June 16, 1962: Canadian Medical Association Journal
https://www.readbyqxmd.com/read/19447254/chitosan-topical-gel-formulation-in-the-management-of-burn-wounds
#10
Ibrahim A Alsarra
Wound healing properties of chitosan with different molecular weight and degree of deacetylation ranges have been examined. The macroscopic image and histopathology were examined using chitosan, Fucidin ointment and to blank. The rate of contraction was evaluated by determination of the unclosed area as a function of time. The treated wounds were found to contract at the highest rate with high molecular weight-high degree of deacetylation chitosan-treated rats as compared to untreated, treated, and Fucidin ointment-treated rats...
July 1, 2009: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/18342097/-tobacco-contact-dermatitis-caused-by-sensitivity-to-sorbic-acid
#11
A Grange-Prunier, M Bezier, G Perceau, P Bernard
BACKGROUND: Contact dermatitis caused by tobacco is rare and poorly understood. In this paper, we report what is to our knowledge, the first case of tobacco contact dermatitis with identification of the causative agent. PATIENTS AND METHODS: A 46-year-old man was hospitalised for diffuse dermatitis originating in the left leg. Subsequent epicutaneous tests indicated that this dermatitis was ascribable to sensitisation to the sorbic acid present in Fucidin cream applied around a chronic wound...
February 2008: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/17852934/susceptibility-to-daptomycin-quinupristin-dalfopristin-and-linezolid-and-some-other-antibiotics-in-clinical-isolates-of-methicillin-resistant-and-methicillin-sensitive-s-aureus-from-the-oslo-area
#12
Bente Jørgen, Patricia Merckoll, Kjetil K Melby
Our study compared the susceptibility of 136 clinical isolates of Staphylococcus aureus and 119 multidrug-resistant Staphylococcus aureus (MRSA) isolates from Oslo to a range of antibiotics, including the novel antibiotics quinupristin-dalfopristin, linezolid and daptomycin. All isolates were susceptible to daptomycin, linezolid and quinupristin-dalfopristin, although a subgroup was less susceptible to the latter. There was no linkage between reduced susceptibility to daptomycin, linezolid or quinupristin-dalfopristin and resistance to other classes of antimicrobials...
2007: Scandinavian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/17726960/-the-experience-of-using-fucidin-and-fucicort-in-the-treatment-of-servicemen-with-pyodermia
#13
V V Glad'ko, S A Masiukova, N N Kakhishvili, G N Tarasenko
No abstract text is available yet for this article.
May 2007: Voenno-medit︠s︡inskiĭ Zhurnal
https://www.readbyqxmd.com/read/17553033/a-cytotoxic-analysis-of-antiseptic-medication-on-skin-substitutes-and-autograft
#14
Q le Duc, M Breetveld, E Middelkoop, R J Scheper, M M W Ulrich, S Gibbs
BACKGROUND: There is an increasing demand for the clinical application of human skin substitutes (HSSs) for treating ulcers, burns and surgical wounds. Due to this increasing demand and due to the simultaneous requirement for the administration of topical antiseptic medications, there is a need to determine potential cytotoxic effects of these medications on HSSs compared with autograft skin. OBJECTIVES: To perform such an evaluation. METHODS: Two different HSSs were used (autologous reconstructed epidermis on fibroblast-populated human dermis and allogeneic reconstructed epidermis on a fibroblast-populated rat collagen gel) and were compared with conventional full-thickness autograft...
July 2007: British Journal of Dermatology
https://www.readbyqxmd.com/read/17144611/-from-l%C3%A3-veapotekets-kemiske-fabrik-to-leo-pharma-a-s
#15
Preben Schrøder
A chronological exposition of the history of LEO Pharma from the limited beginnings in 1908 in "København Løveapotek" to the international pharmaceutical company that exists today. The paper chronicles the various owners, from the pharmacist, August Kongsted, through his son-in-law, Knud Abildgaard to the present ownership by the LEO Foundation, which has during the entire period secured a company independent of foreign capital. Research, the life blood of the company, has resulted in a number of outstanding drugs such as hormones, heparin, diuretics, penicillin, Fucidin, alfacalcidol and calcipotriol...
2005: Theriaca
https://www.readbyqxmd.com/read/16706761/treatment-of-superficial-surgical-wounds-after-removal-of-seborrheic-keratoses-a-single-blinded-randomized-controlled-clinical-study
#16
RANDOMIZED CONTROLLED TRIAL
Steven Goetze, Mirjana Ziemer, Martin Kaatz, Roger D A Lipman, Peter Elsner
BACKGROUND: For the treatment of superficial surgical wounds, there are a number of options, including topical antibiotic ointments, dressings, and specialized wound care materials, such as hydrocolloid dressings. OBJECTIVE: To evaluate the wound-healing activity of a commercially available hydrocolloid wound dressing (Avery H2460, Avery Dennison, Turnhout, Belgium) in comparison with a control treatment (Fucidine cream with Cutiplast sterile dressing) in superficial wounds after surgical removal of seborrheic keratoses...
May 2006: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/16011879/comparison-of-silver-coated-dressing-acticoat-chlorhexidine-acetate-0-5-bactigrass-and-fusidic-acid-2-fucidin-for-topical-antibacterial-effect-in-methicillin-resistant-staphylococci-contaminated-full-skin-thickness-rat-burn-wounds
#17
COMPARATIVE STUDY
Ersin Ulkür, Oral Oncul, Huseyin Karagoz, Esma Yeniz, Bahattin Celiköz
Acticoat, chlorhexidine acetate 0.5%, and fusidic acid 2% were compared to assess the antibacterial effect of an application on experimental 15% BSA, full-thickness burn wounds in rats swabbed 24 h earlier with a 10(8) standard strain of methicillin-resistant Staphylococci. The swabbed organism was recovered from the eschar of all groups except the fusidic acid group. While there were significant differences between treatment groups and control group, the mean eschar concentrations did not differ significantly between the Acticoat and chlorhexidine acetate groups, but there were significant differences between the fusidic acid group and the other treatment groups...
November 2005: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/15150163/detection-of-elements-of-the-staphylococcal-cassette-chromosome-scc-in-a-methicillin-susceptible-meca-gene-negative-homologue-of-a-fucidin-resistant-mrsa
#18
John E Corkill, James J Anson, Paul Griffiths, C Anthony Hart
OBJECTIVES: To determine the DNA relatedness of an outbreak of community-acquired fucidin-resistant methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) isolated from intravenous drug users (IVDUs). MATERIALS AND METHODS: Relatedness was determined by PFGE analysis of macro-restricted chromosome, together with a variety of PCR methods, to determine polymorphisms in the accessory gene regulator (agr) locus, the structure of the staphylococcal cassette chromosome (SCCmec) and the presence or absence of the gene encoding Panton-Valentine leucocidin (PVL)...
July 2004: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/14493690/-fucidin-treatment-of-trichomoniasis-vaginalis-with-negative-results
#19
F RONNIKE, F FUCHS
No abstract text is available yet for this article.
May 18, 1962: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/14490475/-acute-frontal-sinusitis-with-subperiosteal-abscess-treated-with-fucidin
#20
P E RASMUSSEN
No abstract text is available yet for this article.
May 18, 1962: Ugeskrift for Laeger
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