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genitourinary pathology

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https://www.readbyqxmd.com/read/27911069/-urological-pathology-of-lymphatic-origin
#1
A Domènech, A Serrano, I Forner-Cordero, F Gómez, D Maldonado, C Domínguez
OBJECTIVES: Lymphatic disease is a rarely cause of some very unspecific genitourinary manifestations, assuming a diagnostic challenge in most cases. The aim of this paper is to warn about the possible etiology of these urological lymphatic presentations and discuss its management. METHODS: Retrospective review of clinical data in pediatric patients with urological pathology of lymphatic origin between 2008-2014. Three patients, two boys and a girl, were included...
January 25, 2016: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27878359/long-noncoding-rna-gas5-inhibits-malignant-proliferation-and-chemotherapy-resistance-to-doxorubicin-in-bladder-transitional-cell-carcinoma
#2
Hui Zhang, Yan Guo, Yongsheng Song, Chao Shang
PURPOSE: Bladder cancer is the most general malignant cancer in genitourinary system, more than 90% of BCs are bladder transitional cell carcinomas (BTCC). This study aimed to investigate the clinical significance of growth arrest-specific 5 (GAS5) gene and its regulatory effects of malignant proliferation and chemotherapy resistance to doxorubicin in BTCC cells. METHODS: The expression of GAS5 was detected by quantitative real-time PCR. Statistical analysis was used to determine the relationship between GAS5 expression and clinical features and the prognostic value of GAS5 for disease free survival...
November 22, 2016: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/27818982/total-hip-arthroplasty-complications-in-patients-with-or-without-controlled-diabetes-mellitus-during-hospitalization
#3
Fernanda Rezende Campos Falcão, Bruno Anderson Gomes Dias, Liz Araujo Wolfovitch, David Sadigursky
INTRODUCTION: Total hip arthroplasty (THA) is a procedure that aims to restore the function of the hip joint. Diabetes mellitus (DM) is one of the most prevalent comorbidities among patients undergoing THA. DM involves various immunological and metabolic aspects, which lead to limitations and surgical complications. OBJECTIVE: To evaluate the association between THA complications and controlled DM during hospitalization period. METHODS: Cross-sectional research through the analysis of retrospective records of a private hospital in Salvador, Bahia...
September 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/27813338/dutasteride-mediated-morphological-changes-in-the-genitourinary-tract-associated-with-altered-expression-patterns-of-the-androgen-and-estrogen-receptors-in-male-rats
#4
N Enatsu, K Chiba, K Sumii, T Fukuda, K Okada, K Matsushita, M Fujisawa
We evaluated the effects of dutasteride on the genitourinary tract using fifteen 8-week-old male Sprague-Dawley rats. Animals were divided into three groups comprising five animals each and treated as follows. Group A was a control group, members of Group B received oral administration of dutasteride 0.1 mg/kg/day from the age of 8 to 16 weeks, and members of Group C were castrated at the age of 8 weeks. All rats were killed at the age of 16 weeks for the sample collection of blood, bladder, prostate, seminal vesicles, and penis...
November 3, 2016: Andrology
https://www.readbyqxmd.com/read/27801954/the-who-2016-classification-of-testicular-non-germ-cell-tumours-a-review-and-update-from-the-international-society-of-urological-pathology-testis-consultation-panel
#5
REVIEW
Muhammad T Idrees, Thomas M Ulbright, Esther Oliva, Robert H Young, Rodolfo Montironi, Lars Egevad, Daniel Berney, John R Srigley, Jonathan I Epstein, Satish K Tickoo
The World Health Organization (WHO) released a new tumour classification for the genitourinary system in early 2016 after consensus by pathologists with expertise in these organs. It utilized the framework of the 2004 classification and incorporated the most up-to-date information concerning these tumours. In testicular tumours, the majority of the changes occurred in the nomenclature and classification of the germ cell tumours; however, several modifications were also initiated for the non-germ cell tumours...
November 1, 2016: Histopathology
https://www.readbyqxmd.com/read/27785626/neutrophil-gelatinase-associated-lipocalin-utility-in-urologic-conditions
#6
EDITORIAL
Catherine S Forster, Prasad Devarajan
Neutrophil gelatinase-associated lipocalin (NGAL) is best known as a non-invasive early marker of acute kidney injury (AKI). However, recent published reports have described additional utility of both plasma NGAL (pNGAL) and urine NGAL (uNGAL) in various pathologic conditions within the pediatric urinary tract, including urinary tract infection, vesicoureteral reflux (VUR), renal scarring, and obstructive uropathy. These two forms of NGAL have different applications related to their mechanisms of upregulation: pNGAL can serve as a marker of systemic inflammatory conditions, whereas uNGAL is specific for insults to the renal epithelium...
October 26, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/27778072/robotic-site-adjusted-levator-transection-for-carcinoma-of-the-rectum-a-modification-of-the-existing-cylindrical-abdominoperineal-resection-for-eccentrically-located-tumors
#7
Ajit Pai, Saleh Mohamed Eftaiha, George Melich, John J Park, Pey-Yi Kevin Lin, Leela M Prasad, Slawomir J Marecik
BACKGROUND: Today, extralevator abdominoperineal resection is the standard of care for low rectal cancers with sphincter involvement or location precluding anastomosis. This procedure, while effective from an oncologic point of view, is morbid, with a high incidence of wound complications and genitourinary, and sexual dysfunction. We present a modification of this procedure via a robotic approach, which maintains the radicality while reducing the soft tissue loss and potentially the morbidity...
October 24, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27765594/testicular-hypoplasia-is-driven-by-defective-vascular-formation
#8
Pankaj Dangle, Cláudia Salgado, Miguel Reyes-Mugica, Francis Schneck, Michael Ost, Sunder Sims-Lucas
OBJECTIVE: To determine if vanishing testis could result from a fault in embryological development as a result of an arrest in endothelial cell migration rather than secondary to just a random physical torsion/twist. .A testicular nubbin or vanishing testis is considered to be secondary to a neonatal torsion and is usually associated with a hemosiderin deposit. METHODS: Cases of vanishing testis excision were compared with age-matched controls from cadaveric testes without known genitourinary pathology...
October 17, 2016: Urology
https://www.readbyqxmd.com/read/27761190/left-anterior-descending-coronary-artery-and-multiple-peripheral-mycotic-aneurysms-due-to-mycobacterium-bovis-following-intravesical-bacillus-calmette-guerin-therapy-a-case-report
#9
Petar Duvnjak, Mario Laguna
The use of live attenuated intravesicular Bacillus Calmette-Guerin (BCG) therapy is a generally accepted safe and effective method for the treatment of superficial transitional cell carcinoma (TCC) of the bladder. Although rare, < 5% of patient's treated with intravesicular BCG therapy may develop potentially serious complications, including localized infections to the genitourinary tract, mycotic aneurysms and osteomyelitis. We present here a case of a 63-year-old male who developed left coronary and multiple peripheral M...
August 2016: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/27752161/-diagnosis-and-treatment-of-t1a-t1b-prostate-cancer
#10
Z Liu, C Luo, S Hu, Y Fan, Z H Liu, X Y Yang, Q Shen, L B Liu, W K Han, L Q Zhou, W Yu, Q He, Q Zhang, J Jin
OBJECTIVE: To explore the clinical pathological characteristics and improve the recognition in the diagnosis and treatment of incidental (stage T1a-T1b) prostate cancer. METHODS: Seven hundred and seventy-one patients who underwent TURP from May 2004 to September 2013 were analyzed retrospectively. In our institution, TURP specimens should be totally submitted in an extensive sampling method. The tumor area was outlined by estimation of an experienced genitourinary pathologist and calculated by the image analysis system software (Image J 1...
October 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27734016/pneumonia-and-pleural-empyema-due-to-a-mixed-lactobacillus-spp-infection-as-a-possible-early-esophageal-carcinoma-signature
#11
Eleftheria Chaini, Nikolaos D Chainis, Anastasios Ioannidis, Maria Magana, Chryssoula Nikolaou, Joseph Papaparaskevas, Melina-Vassiliki Liakata, Panagiotis Katopodis, Leonidas Papastavrou, George P Tegos, Stylianos Chatzipanagiotou
Lactobacilli are human commensals found in the gastrointestinal and genitourinary tract. Although generally conceived as non-pathogenic microorganisms, the existence of several reports implicating them in certain severe pathological entities renders this species as opportunistic pathogens. The case of a 58-year-old woman with mixed Lactobacillus infection is described. The patient was admitted in an outpatient clinic with community acquired pneumonia, and on the third day of hospitalization she presented rapid pneumonia deterioration...
2016: Frontiers in Medicine
https://www.readbyqxmd.com/read/27720562/pediatric-renal-and-genitourinary-tract-tumors-and-the-contributions-of-dr-louis-pepper-dehner-therewith
#12
Jason A Jarzembowski
Dr. Louis "Pepper" Dehner is an internationally renowned surgical pathologist, especially in the subspecialty of pediatric pathology. Although his clinical and academic expertise are broad, with over 400 published articles, some of his most intriguing contributions have been in the area of pediatric renal and genitourinary pathology. This review focuses on the entities in these following organ systems where he has focused his efforts: malignant rhabdoid tumor, renal medullary carcinoma, Ewing sarcoma/peripheral neuroectodermal tumor, and the DICER1-related lesions cystic nephroma, embryonal rhabdomyosarcoma of the uterine cervix, and Sertoli-Leydig cell tumor...
August 31, 2016: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/27708254/-data-analysis-of-subacute-patients-with-registered-information-in-the-minimum-basic-data-set-for-social-healthcare-cmbd-rss-spain
#13
Cristina Meléndez Frigola, Elena Arroyo Borrell, Marc Saez
OBJECTIVE: It is necessary to deepen in the knowledge of the Basic Minimum Set of Data (CMBD-RSS) of patients with chronic pathology associated and frequent hospitalisations (the subacute care). The aim of this study was to analyse the sanitary information of these patients, once initiated the subacute program. METHODS: We used data of 660 patients hospitalised in the subacute care unit at the Santa Caterina Hospital, sanitary region of Girona, from October 2013 to December 2014...
October 3, 2016: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/27694784/myogenic-temporomandibular-disorders-clinical-systemic-comorbidities-in-a-female-population-sample
#14
M de-Pedro-Herráez, J Mesa-Jiménez, C Fernández-de-Las-Peñas, J-L de-la-Hoz-Aizpurua
BACKGROUND: Myogenic temporomandibular disorders (MTMD) frequently coexist with other clinical conditions in the same individual. In the last decades, several authors have analyzed these comorbidities looking for the origin of this overlapping. Objetives: The aim of this study was to perform a comparative anaylisis between a group of patients with MTMD and a control group of dental patients without dysfunctional pathology to assess whether there are significant differences in the presence of systemic medical comorbidities between the two groups...
November 1, 2016: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27688894/prevalence-of-malnutrition-in-hospitalised-children-retrospective-study-in-a-spanish-tertiary-level-hospital
#15
Teodoro Durá-Travé, Isabel San Martin-García, Fidel Gallinas-Victoriano, Ibone Vaquero Iñigo, Aida González-Benavides
OBJECTIVE: To analyse the prevalence of malnutrition among paediatric patients at the time of hospital admission throughout a calendar year in a tertiary-level hospital and to identify those patients and/or groups of pathologies with a higher risk of malnutrition. DESIGN: Observational (retrospective evaluation of nutrition status). SETTING: Navarra Hospital Complex, Pamplona, Spain. PARTICIPANTS: A total of 852 patients hospitalised in 2013 in a Spanish tertiary-level paediatric hospital (462 males and 390 females)...
September 2016: JRSM Open
https://www.readbyqxmd.com/read/27688331/a-new-catalog-of-microbiological-tools-for-women-s-infectious-disease-research
#16
Amanda L Lewis, Warren G Lewis
Genitourinary infections pose serious health risks. But, little is known about how genitourinary bacteria attach, maintain colonization, compete for resources, and cause pathology. In this issue, we introduce a new set of 62 genitourinary reference strains of bacteria and their genomes to spur experimental research on infectious diseases that impact women.
September 29, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27661267/successful-repair-of-iatrogenic-ureteral-injury-in-a-patient-with-ectopic-crossed-and-fused-right-kidney-by-ureteroureterostomy
#17
N Gabunia, Iv Rodionov, T Chigogidze
Congenital renal malformations are the most common congenital malformations in humans, the most common being horseshoe kidney with joined lower poles present in up to 0.25% of general population. To the contrary renal fusions with ectopia are amongst the rare malformations affecting 1 in 2000 examined cadavers. Males are affected slightly more often then females (3:2), left to right crosses being more frequent. The value of early diagnosis of asymptomatic renal malformation is uncertain, except when other abnormalities might point to them and they can affect the clinical management strategy (severe ear deformity with facial malformation, gynecological abnormalities)...
July 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27635292/effects-of-clinical-laboratuary-and-pathological-features-on-successful-sperm-retrieval-in-non-obstructive-azoospermia
#18
Çağrı Güneri, Turgut Alkibay, Lütfi Tunç
OBJECTIVE: The study aims to evaluate the correlation of testicular sperm extraction (TESE) and histopathology with various features of non-obstructive azoospermia (NOA) cases who consulted to our university-based infertility clinic, and the probability of prompting couples about TESE success and to investigate the cost reduction chance through cost-beneficial aspects. MATERIAL AND METHODS: One hundred and twenty-five patients were enrolled in this study. Age, unprotected intercourse period, age of puberty, and concomittant diseases were noted...
September 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27611781/urinary-microbiota-associated-with-preterm-birth-results-from-the-conditions-affecting-neurocognitive-development-and-learning-in-early-childhood-candle-study
#19
Nicholas J Ollberding, Eszter Völgyi, Maurizio Macaluso, Ranjit Kumar, Casey Morrow, Frances A Tylavsky, Chandrika J Piyathilake
Preterm birth (PTB) is the leading cause of infant morbidity and mortality. Genitourinary infection is implicated in the initiation of spontaneous PTB; however, examination of the urinary microbiota in relation to preterm delivery using next-generation sequencing technologies is lacking. In a case-control study nested within the Conditions Affecting Neurocognitive Development and Learning in Early Childhood (CANDLE) study, we examined associations between the urinary microbiota and PTB. A total of 49 cases (delivery < 37 weeks gestation) and 48 controls (delivery ≥ 37 weeks gestation) balanced on health insurance type were included in the present analysis...
2016: PloS One
https://www.readbyqxmd.com/read/27569435/molecular-analysis-of-low-grade-prostate-cancer-using-a-genomic-classifier-of-metastatic-potential
#20
Eric A Klein, María Santiago-Jiménez, Kasra Yousefi, Bruce A Robbins, Edward M Schaeffer, Bruce J Trock, Jeffrey Tosoian, Zaid Haddad, Seong Ra, R Jeffrey Karnes, Robert B Jenkins, John C Cheville, Robert B Den, Adam P Dicker, Elai Davicioni, Stephen J Freedland, Ashley E Ross
PURPOSE: We determined how frequently histological Gleason 3 + 3 = 6 tumors have the molecular characteristics of disease with metastatic potential. MATERIALS AND METHODS: We analyzed prostatectomy tissue from 337 patients with Gleason 3 + 3 disease. All tissue was re-reviewed in blinded fashion by genitourinary pathologists using 2005 ISUP (International Society of Urological Pathology) Gleason grading criteria. A previously validated Decipher® metastasis signature was calculated in each case based on a locked model...
August 26, 2016: Journal of Urology
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