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Infectologia

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https://www.readbyqxmd.com/read/28729186/-tuberculosis-treatment-for-children-an-update
#1
María José Mellado Peña, Begoña Santiago García, Fernando Baquero-Artigao, David Moreno Pérez, Roi Piñeiro Pérez, Ana Méndez Echevarría, José Tomás Ramos Amador, David Gómez-Pastrana Durán, Antoni Noguera Julian
Tuberculosis (TB) is the most important infectious disease all over the world, with a high morbidity and mortality. Pediatric tuberculosis has been a neglected epidemic, due to the difficulties in assessing its global impact, reduced incidence and lower infectivity compared to adults. In 2015, the WHO reported 1 million cases of paediatric TB and 169,000 deaths. In Europe, the emergence of MDR TB is a major concern, representing 16% of the new diagnosis in Eastern Europe. In 2014, it was estimated that about 219,000 children were infected by MDR-TB-strains in Europe, and 2,120 developed the disease...
July 17, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28632831/-antiseptics-and-disinfectants-aiming-at-rational-use-recommendations-of-the-advisory-committee-on-healthcare-associated-infections-sociedad-chilena-de-infectolog%C3%A3-a
#2
Alexis Diomedi, Eiiana Chacón, Luis Delpiano, Beatrice Hervé, M Irene Jemenao, Myriam Medel, Marcela Quintanilla, Gisela Riedel, Javier Tinoco, Marcela Cifuentes
Proper use of antiseptics and disinfectants, is an essential tool to prevent the spread of infectious agents and to control of healthcare-associated infections (HAI). Given the increasing importance of environmental aspects, as well as several advances and updates in the field of its proper use at local and intemational level, the SOCHINF HAI Advisory Committee considers that it is necessary to develop a guide for the rational use of antiseptics and disinfectants, which it will provide consistent scientific basis with that purpose...
April 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28612497/pharmacotherapy-follow-up-role-in-active-malaria-surveillance-in-a-travel-medicine-centre-outside-the-transmission-area-in-brazil
#3
R S Pedro, P Brasil, A Pina-Costa, C R Machado, L S Damasceno, C T Daniel-Ribeiro, L Guaraldo
WHAT IS KNOWN AND OBJECTIVE: Malaria is a potentially severe disease, widespread in tropical and subtropical areas. Apart from parasite drug resistance, which receives the largest share of attention, several factors directly influence the response to antimalarial treatment such as incorrect doses, adverse drug events, lack of adherence to treatment, drug quality and drug-drug interactions. Pharmacotherapy follow-up can be used to monitor and improve the effectiveness of treatment, prevent drug-related problems and ensure patient safety...
June 13, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28562743/reproductive-aspects-and-knowledge-of-family-planning-among-women-with-acquired-immunodeficiency-syndrome
#4
Ivana Cristina Vieira de Lima, Maria da Conceição Dos Santos Oliveira Cunha, Gilmara Holanda da Cunha, Marli Teresinha Gimeniz Galvão
OBJECTIVE: To analyze the reproductive aspects and knowledge of family planning among women with Acquired Immunodeficiency Syndrome (AIDS). METHOD: Cross-sectional and descriptive study carried out from January to December, 2015, in the outpatient care of infectious disease unit in a hospital located in Fortaleza, Ceará. Data were collected through a form applied by interview in a private setting. RESULTS: 102 women participated in the study...
May 25, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28291051/thirty-day-readmission-rates-in-an-hiv-infected-cohort-from-rio-de-janeiro-brazil
#5
Lara E Coelho, Sayonara R Ribeiro, Andre M Japiassu, Ronaldo I Moreira, Priscila C Lara, Valdilea G Veloso, Beatriz Grinsztejn, Paula M Luz
BACKGROUND: The 30-day readmission rate is an indicator of the quality of hospital care and transition to the outpatient setting. Recent studies suggest HIV infection might increase the risk of readmission although estimates of 30-day readmission rates are unavailable among HIV-infected individuals living in middle/low-income settings. Additionally, factors that may increase readmission risk in HIV-infected populations are poorly understood. METHODS: Thirty-day readmission rates were estimated for HIV-infected adults from the Instituto Nacional de Infectologia Evandro Chagas/Fiocruz cohort in Rio de Janeiro, Brazil, from January 2007 to December 2013...
August 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28198956/evaluating-pharmaceutical-waste-disposal-in-pediatric-units
#6
Maria Angélica Randoli de Almeida, Ana Maria Miranda Martins Wilson, Maria Angélica Sorgini Peterlini
OBJECTIVE: To verify the disposal of pharmaceutical waste performed in pediatric units. METHOD: A descriptive and observational study conducted in a university hospital. The convenience sample consisted of pharmaceuticals discarded during the study period. Handling and disposal during preparation and administration were observed. Data collection took place at pre-established times and was performed using a pre-validated instrument. RESULTS: 356 drugs disposals were identified (35...
November 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/27905629/-reasons-to-recommend-vaccination-against-dengue-in-easter-island-immunization-advisory-committee-of-sociedad-chilena-de-infectolog%C3%A3-a
#7
Alberto Fica, Marcela Potin, Gabriela Moreno, Liliana Véliz, Jaime Cerda, Carola Escobar, Jan Wilhelm
Dengue was first diagnosed on Easter Island on year 2002 and thereafter recurrent outbreaks have occurred involving different serotypes of dengue virus. Its vector, Aedes aegypti has not been eliminated despite the small size of the island. Conditions at the local hospital preclude adequate management of severe and hemorrhagic cases due to the absence of a Critical Care Unit as well as no availability of platelets, or plasma units for transfusion. Besides, transfer, of severely affected patients to continental Chile is cumbersome, slow and expensive...
August 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27737420/palliative-care-for-patients-with-hiv-aids-admitted-to-intensive-care-units
#8
Paola Nóbrega Souza, Erique José Peixoto de Miranda, Ronaldo Cruz, Daniel Neves Forte
OBJECTIVE: To describe the characteristics of patients with HIV/AIDS and to compare the therapeutic interventions and end-of-life care before and after evaluation by the palliative care team. METHODS: This retrospective cohort study included all patients with HIV/AIDS admitted to the intensive care unit of the Instituto de Infectologia Emílio Ribas who were evaluated by a palliative care team between January 2006 and December 2012. RESULTS: Of the 109 patients evaluated, 89% acquired opportunistic infections, 70% had CD4 counts lower than 100 cells/mm3, and only 19% adhered to treatment...
September 2016: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/27699970/asymptomatic-cryptococcal-antigen-prevalence-detected-by-lateral-flow-assay-in-hospitalised-hiv-infected-patients-in-s%C3%A3-o-paulo-brazil
#9
José E Vidal, Carolina Toniolo, Adriana Paulino, Arnaldo Colombo, Marilena Dos Anjos Martins, Cristina da Silva Meira, Vera Lucia Pereira-Chioccola, Claudia Figueiredo-Mello, Tiago Barros, Jequelie Duarte, Fernanda Fonseca, Mirella Alves Cunha, Clara Mendes, Taiana Ribero, Marcia Dos Santos Lazera, Radha Rajasingham, David R Boulware
OBJECTIVE: To determine the prevalence of asymptomatic cryptococcal antigen (CRAG) using lateral flow assay (LFA) in hospitalised HIV-infected patients with CD4 counts <200 cells/μl. METHODS: Hospitalised HIV-infected patients were prospectively recruited at Instituto de Infectologia Emilio Ribas, a tertiary referral hospital to HIV-infected patients serving the São Paulo State, Brazil. All patients were >18 years old without prior cryptococcal meningitis, without clinical suspicion of cryptococcal meningitis, regardless of antiretroviral (ART) status, and with CD4 counts <200 cells/μl...
December 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27694731/effectiveness-of-tipranavir-versus-darunavir-as-a-salvage-therapy-in-hiv-1-treatment-experienced-patients
#10
COMPARATIVE STUDY
Juan Carlos Domínguez-Hermosillo, José Antonio Mata-Marin, Norma Estela Herrera-González, Marcelino Chávez-García, Gloria Huerta-García, Nohemí Nuñez-Rodríguez, José Gerardo García-Gámez, Anai Jiménez-Romero, Jesús Enrique Gaytán-Martínez
INTRODUCTION: Although both tipranavir (TPV) and darunavir (DRV) represent important options for the management of patients with multi-protease inhibitor (PI)-resistant human immunodeficiency virus (HIV), currently there are no studies comparing the effectiveness and safety of these two drugs in the Mexican population. The aim of this study was to compare the effectiveness of TPV versus DRV as a salvage therapy in HIV-1 treatment-experienced patients. METHODOLOGY: This was a comparative, prospective, cohort study...
September 30, 2016: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/27658875/mortality-in-hiv-infected-women-heterosexual-men-and-men-who-have-sex-with-men-in-rio-de-janeiro-brazil-an-observational-cohort-study
#11
Lara Coelho, Beatriz Grinsztejn, Jessica L Castilho, Raquel De Boni, Marcel S B Quintana, Dayse P Campos, Sayonara R Ribeiro, Antonio G Pacheco, Valdilea G Veloso, Paula M Luz
BACKGROUND: Mortality in HIV-infected individuals might differ by sex and mode of HIV acquisition. We aimed to study mortality in HIV-infected women, heterosexual men, and men who have sex with men (MSM) in a cohort from Rio de Janeiro, Brazil. METHODS: In this observational cohort study, we included HIV-infected women, heterosexual men, and MSM (aged ≥18 years) from the Instituto Nacional de Infectologia Evandro Chagas database who were enrolled between Jan 1, 2000, and Oct 30, 2011, and who had at least 60 days of follow-up...
October 2016: Lancet HIV
https://www.readbyqxmd.com/read/27461407/poor-retention-in-early-care-increases-risk-of-mortality-in-a-brazilian-hiv-infected-clinical-cohort
#12
Daniel S Teixeira da Silva, Paula M Luz, Jordan E Lake, Sandra W Cardoso, Sayonara Ribeiro, Ronaldo I Moreira, Jesse L Clark, Valdilea G Veloso, Beatriz Grinsztejn, Raquel B De Boni
Retention in early HIV care has been associated with decreased mortality and improved viral suppression, however the consequences of poor retention in early care in Brazil remain unknown. We assessed the effect of poor retention on mortality in a Brazilian HIV-infected clinical cohort. The analysis included ART-naïve, HIV-infected adults linked to care at the Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz between 2000 and 2010, who did not become pregnant nor participate in a clinical trial during the first two years in care (early care)...
February 2017: AIDS Care
https://www.readbyqxmd.com/read/27366076/prescription-of-antibiotics-in-community-acquired-pneumonia-in-children-are-we-following-the-recommendations
#13
Eduardo Jorge da Fonseca Lima, Débora Ellen Pessoa Lima, George Henrique Cordeiro Serra, Maria Anaide Zacche S Abreu E Lima, Maria Júlia Gonçalves de Mello
OBJECTIVE: To assess the adequacy of antibiotic prescription in children hospitalized for pneumonia in a reference pediatric hospital in Brazil. METHODS: This was a cross-sectional study involving children aged between 1 month and 5 years who were hospitalized between October 2010 and September 2013. The classification of community-acquired pneumonia (CAP) was based on the clinical and radiological criteria of the World Health Organization (WHO). The analysis of antibiotic adequacy was performed according to the main guidelines on CAP treatment, which include the WHO guidelines, Brazilian Society of Pediatrics guidelines, and international guidelines (Pediatrics Infectious Diseases Society, the Infectious Disease Society of America, British Thoracic Society, and Consenso de la Sociedad latinoamericana de Infectología)...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27329066/diabetes-mellitus-is-associated-with-increased-death-rates-among-hiv-infected-patients-in-rio-de-janeiro-brazil
#14
Rodrigo C Moreira, Antonio G Pacheco, Adelzon Paula, Sandra W Cardoso, Ronaldo I Moreira, Sayonara R Ribeiro, Estevão P Nunes, Maria R Guimarães, Fernanda C Mello, Valdilea G Veloso, Beatriz Grinsztejn
Diabetes mellitus (DM) is a major cause of morbidity worldwide and a known factor leading to increased risk of death, especially in conjunction with other risk factors. In this study, we evaluated the prevalence of DM among HIV-infected patients and its association with overall mortality. All HIV-infected patients 18 years or older who were followed in the Instituto Nacional de Infectologia Evandro Chagas (INI) cohort from January 1991 to December 2011 were included. Time-updated covariables included DM status, calendar year, combination antiretroviral therapy (cART), and CD4 cell counts...
December 2016: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/27314998/-torch-syndrome-rational-approach-of-pre-and-post-natal-diagnosis-and-treatment-recommendations-of-the-advisory-committee-on-neonatal-infections-sociedad-chilena-de-infectolog%C3%A3-a-2016
#15
REVIEW
Fernanda Cofre, Luis Delpiano, Yenis Labraña, Alejandra Reyes, Alejandra Sandoval, Giannina Izquierdo
There is a lot of bacterial, viral or parasite infections who are able to be transmitted vertically from the mother to the fetus or newborn which implicates an enormous risk for it. The TORCH acronym is used universally to refer to a fetus or newborn which presents clinical features compatible with a vertically acquired infection and allows a rational diagnostic and therapeutic approach. The traditional "TORCH test" is nowadays considered not appropriate and it has been replaced for specific test for specific pathogens under well defined circumstances...
April 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27079399/-diagnostic-criteria-and-treatment-of-childhood-tuberculosis-executive-summary
#16
REVIEW
(no author information available yet)
No abstract text is available yet for this article.
April 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/26914078/-recommendations-for-palivizumab-use-update-2015
#17
Silvia Fernández Jonusas, Deleys Albas Maubett, Daniela Satragno, Adriana Cattaino, Margarita Martin Alonso, Cecilia Rubio, Ricardo Nieto
This recommendation updates the Argentinean Pediatrics' Neonatal Committee (CEFEN) ones published in 2007. The respiratory syncytial virus is the most frequent agent for lower respiratory infection. Tiny premature, bronchopulmonary dysplasia and significant hemodynamic congenital heart disease babies are the most vulnerable populations. Palivizumab is a humanized monoclonal antibody against respiratory syncytial virus used in the cold season. These recommendations are based on the scientific review of the literature published up to date...
February 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/26687400/-for-the-health-protection-of-refugee-children
#18
EDITORIAL
L M Prieto, M García López Hortelano, M J Mellado Peña
No abstract text is available yet for this article.
February 2016: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/26436925/-an-analysis-of-chilean-biomedical-publications-in-pubmed-in-the-years-2008-2009
#19
Gloria Valdés S, Fernanda Pérez G, Humberto Reyes B
BACKGROUND: During the years 2008 and 2009, 1,191 biomedical articles authored by Chilean investigators working in Chile were indexed in PubMed. AIMS: To evaluate the potential visibility of those articles, according to scientometric indexes of the journals where they were published. METHODS: Those journals where the articles had been published were identified and each journal’s Impact Factor (JIF), 5-year JIF, SCImago Journal Rank (SJR), SCImago Quartiles (Q) for 2010 and the Source Normalized Impact per Paper (SNIP) for 2008-2009 were identified...
August 2015: Revista Médica de Chile
https://www.readbyqxmd.com/read/26409726/-consensus-document-on-post-exposure-prophylaxis-against-hiv-hbv-and-hcv-in-adults-and-children
#20
(no author information available yet)
OBJECTIVE: This consensus document is an update of occupational and non-occupational prophylaxis guidelines in HIV-patients, promoting appropriate use of them, from the standpoint of care. METHODS: This document has been approved by expert panel of SPNS, GESIDA, SEMST and different scientific societies related, after reviewing the results of efficacy and safety clinical trials, cohort and pharmacokinetic studies published in biomedical journals (PubMed and Embase) or presented at conferences and different guidelines...
February 2016: Enfermedades Infecciosas y Microbiología Clínica
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