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https://www.readbyqxmd.com/read/29302786/intraoperative-changes-in-corneal-structure-during-excimer-laser-phototherapeutic-keratectomy-ptk-assessed-by-intraoperative-optical-coherence-tomography
#1
Sebastian Siebelmann, Jens Horstmann, Paula Scholz, Björn Bachmann, Mario Matthaei, Manuel Hermann, Claus Cursiefen
PURPOSE: Excimer laser phototherapeutic keratectomy (PTK) is a safe treatment for superficial corneal opacities, e.g., in corneal dystrophies or degenerations. Nevertheless, no standardized treatment protocols are available and intraoperative monitoring was not possible, so far. Here we evaluate the potential benefits of the intraoperative assessment by microscope-integrated intraoperative optical coherence tomography (MI-OCT) of corneal optical properties during PTK. METHODS: Retrospective study of eight patients (one male, seven females; age range, 43-80 years, mean = 66...
January 4, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29301304/the-development-evaluation-of-economic-zones-in-china
#2
Wei Liu, Hong-Bo Shi, Zhe Zhang, Sang-Bing Tsai, Yuming Zhai, Quan Chen, Jiangtao Wang
After the Chinese reform and opening up, the construction of economic zones, such as Special Economic Zones, Hi-tech Zones and Bonded Zones, has played an irreplaceable role in China's economic development. Currently, against the background of Chinese economic transition, research on development evaluation of economic zones has become popular and necessary. Similar research usually focuses on one specific field, and the methods that are used to evaluate it are simple. This research aims to analyse the development evaluation of zones by synthesis...
January 2, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29231514/-development-of-non-traumatic-pain-acupuncture-moxibustion-apparatus-and-its-industrialization
#3
Qian Ran, Xingpeng Jiang
In order to alleviate the discomforts induced by the invasive manipulation of acupuncture, improve the acceptability of acupuncture-moxibustion therapy and promote the application of it in healthcare, the research team developed the non-traumatic-pain acupuncture-moxibustion apparatus for disease treatment and prevention as well as healthcare, such as crude herbal moxibustion plus cupping device (cupping device), the healthcare cloth for warming the governor vessel (healthcare cloth) and the governor vessel intelligent diagnosis apparatus (diagnosis apparatus)...
June 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29201110/presentation-of-a-novel-model-for-evaluation-of-commercialization-of-research-and-development-case-study-of-the-pharmaceutical-biotechnology-industry
#4
Hassan Emami, Reza Radfar
The current situation in Iran suggests an appropriate basis for developing biotechnology industries, because the patents for the majority of hi-tech medicines registered in developed countries are ending. Biosimilar and technology-oriented companies which do not have patents will have the opportunity to enter the biosimilar market and move toward innovative initiatives. The present research proposed a model by which one can evaluate commercialization of achievements obtained from research with a focus on the pharmaceutical biotechnology industry...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/29149895/novel-insights-into-chromosomal-conformations-in-cancer
#5
REVIEW
Ruobing Jia, Peiwei Chai, He Zhang, Xianqun Fan
Exploring gene function is critical for understanding the complexity of life. DNA sequences and the three-dimensional organization of chromatin (chromosomal interactions) are considered enigmatic factors underlying gene function, and interactions between two distant fragments can regulate transactivation activity via mediator proteins. Thus, a series of chromosome conformation capture techniques have been developed, including chromosome conformation capture (3C), circular chromosome conformation capture (4C), chromosome conformation capture carbon copy (5C), and high-resolution chromosome conformation capture (Hi-C)...
November 17, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28868968/can-regenerative-medicine-and-nanotechnology-combine-to-heal-wounds-the-search-for-the-ideal-wound-dressing
#6
Payam Zarrintaj, Abolfazl Salehi Moghaddam, Saeed Manouchehri, Zhaleh Atoufi, Anahita Amiri, Mohammad Amir Amirkhani, Mohammad Ali Nilforoushzadeh, Mohammad Reza Saeb, Michael R Hamblin, Masoud Mozafari
Skin is the outermost covering of the human body and at the same time the largest organ comprising 15% of body weight and 2 m2 surface area. Skin plays a key role as a barrier against the outer environment depending on its thickness, color and structure, which differ from one site to another. The four major types of problematic wounds include ulcers (diabetic, venous, pressure) and burn wounds. Developing novel dressings helps us to improve the wound healing process in difficult patients. Recent advances in regenerative medicine and nanotechnology are revolutionizing the field of wound healing...
October 2017: Nanomedicine
https://www.readbyqxmd.com/read/28629101/a-mini-review-on-hydrogels-classification-and-recent-developments-in-miscellaneous-applications
#7
REVIEW
Kokkarachedu Varaprasad, Gownolla Malegowd Raghavendra, Tippabattini Jayaramudu, Murali Mohan Yallapu, Rotimi Sadiku
Hydrogels are composed of three-dimensional smart and/or hungry networks, which do not dissolve in water but swell considerably in an aqueous medium, demonstrating an extraordinary ability to absorb water into the reticulated structure. Such inherent feature is a subject of considerable scientific research interest which leads to a dominating path in extending their potential in hi-tech applications. Over the past decades, significant progress has been made in the field of hydrogels. Further, explorations are continuously being made in all directions at an accelerated pace for their extensive usage...
October 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28625369/rationale-and-design-of-the-hunting-for-the-off-target-properties-of-ticagrelor-on-endothelial-function-and-other-circulating-biomarkers-in-humans-hi-tech-trial
#8
RANDOMIZED CONTROLLED TRIAL
Sara Ariotti, Maarten van Leeuwen, Salvatore Brugaletta, Sergio Leonardi, Kristiaan Martijn Akkerhuis, Emrush Rexhaj, Gladys Janssens, Luis Ortega-Paz, Diego Rizzotti, Jan C van den Berge, Dierik Heg, Gloria Francolini, Stephan Windecker, Marco Valgimigli
BACKGROUND: Among the 3 approved oral P2Y12 inhibitors for the treatment for patients with acute coronary syndrome (ACS), ticagrelor, but not prasugrel or clopidogrel, has been associated with off-target properties, such as improved endothelial-dependent vasomotion and increased adenosine plasma levels. METHODS: The HI-TECH study (NCT02587260) is a multinational, randomized, open-label, crossover study with a Latin squares design, conducted at 5 European sites, in which patients free from recurrent ischemic or bleeding events ≥30 days after a qualifying ACS were allocated to sequentially receive a 30 ± 5-day treatment with prasugrel, clopidogrel, and ticagrelor in random order...
July 2017: American Heart Journal
https://www.readbyqxmd.com/read/28546705/sinonasal-mass-a-recent-study-of-its-clinicopathological-profile
#9
P Agarwal, R Panigrahi
A variety of non-neoplastic and neoplastic conditions involving the nasal cavity, paranasal sinuses (PNS), and nasopharynx are commonly encountered in clinical practice. The objectives of the study were to identify various pathological conditions that present with sinus or nasal mass, to understand their varied clinical behavior, to know the distribution of various lesions among the different age and sex groups, and to study the management of sinonasal masses and its outcome on follow-up. A prospective study was carried out from September 2013 to August 2015, in the Otorhinolaryngology Department of Hi-Tech Medical College & Hospital, Bhubaneswar, Odisha...
June 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28299367/ivf-in-sri-lanka-a-concise-history-of-regulatory-impasse
#10
Bob Simpson
This article outlines the development of IVF in Sri Lanka from the first successful births in the late 1990s and over the subsequent 15 years. It is based on anthropological fieldwork carried out at various points during this period. The piece focuses on the challenges entailed in achieving regulation of the new reproductive technologies against a backdrop of: (i) a bitter civil war; (ii) a complex mosaic of different religious traditions (specifically, Buddhism, Catholicism, Hinduism and Islam); and (iii) a shift towards neo-liberal marketization, particularly in relation to specialist and hi-tech medical interventions...
June 2016: Reproductive Biomedicine & Society Online
https://www.readbyqxmd.com/read/28095321/cellulose-to-depolymerize%C3%A2-or-not-to
#11
REVIEW
Sergiu Coseri
Oxidation of the primary OH groups in cellulose is a pivotal reaction both at lab and industrial scale, leading to the value-added products, i.e. oxidized cellulose which have tremendous applications in medicine, pharmacy and hi-tech industry. Moreover, the introduction of carboxyl moieties creates prerequisites for further cellulose functionalization through covalent attachment or electrostatic interactions, being an essential achievement designed to boost the area of cellulose-based nanomaterials fabrication...
March 2017: Biotechnology Advances
https://www.readbyqxmd.com/read/27722408/role-of-a-singlet-diradical-character-in-carbon-nanomaterials-a-novel-hot-spot-for-efficient-nonlinear-optical-materials
#12
Shabbir Muhammad, Masayoshi Nakano, Abdullah G Al-Sehemi, Yasutaka Kitagawa, Ahmad Irfan, Aijaz R Chaudhry, Ryohei Kishi, Soichi Ito, Kyohei Yoneda, Kotaro Fukuda
Carbon atoms have the potential to produce a variety of fascinating all-carbon structures with amazing electronic and mechanical properties. Over the last few decades, several efforts have been made using experimental and computational techniques to functionalize graphene, carbon nanotubes and fullerenes for potential use in modern hi-tech electronic, medicinal, optical and nonlinear optical (NLO) applications. Since photons replaced electrons as a carrier of information, the field of NLO material design has drawn immense interest in contemporary materials science...
September 30, 2016: Nanoscale
https://www.readbyqxmd.com/read/27478445/patient-engagement-and-patient-support-programs-in-allergy-immunotherapy-a-call-to-action-for-improving-long-term-adherence
#13
REVIEW
Pascal Demoly, Giovanni Passalacqua, Oliver Pfaar, Joaquin Sastre, Ulrich Wahn
Allergy immunotherapy (AIT) is acknowledged to produce beneficial mid- and long-term clinical and immunologic effects and increased quality of life in patients with allergic respiratory diseases (such as allergic rhinoconjunctivitis and allergic asthma). However, poor adherence to AIT (due to intentional and/or non-intentional factors) is still a barrier to achieving these benefits. There is an urgent need for patient support programs (PSPs) that encompass communication, educational and motivational components...
2016: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/27164752/-state-of-vegetative-regulation-in-workers-exposed-to-vibration-at-work-during-industrial-implementation-of-hi-tech-pneumoinstruments
#14
V A Drobyshev, L A Shpagina, L A Panacheva, O N Gerasimenko, S G Abramovich, I N Smirnova
The study was conducted on aircraft-building enterprise during production microcycle (before working shift start, during last working hour and in an hour after the shift end)--spectral analysis covered variability of heart rhythm in 70 male assembler riveters aged 25-59, divided into 2 groups in accordance with industrial equipment used. The group 1 used standard vibroinstrument, the group 2--pneumoinstruments with low vibration velocity parameters. Triple study during the working shift revealed in group 2 an adequate reaction of vegetative nervous system to vibration, in group 1 a negative trend was seen with centralization of regulatory processes and absence of adequate recovery in an hour after work...
2016: Meditsina Truda i Promyshlennaia Ekologiia
https://www.readbyqxmd.com/read/26904530/association-of-a-hi-tech-with-a-bio-tech-technique-in-the-treatment-of-early-osteoarthritis-of-the-knee-a-case-report
#15
Francesco Mattia Uboldi, Paolo Ferrua, Andrea Parente, Stefano Pasqualotto, Massimo Berruto
Meniscal replacement to treat early osteoarthritis of the knee after meniscectomy may be accompanied by other surgical procedures to treat factors predisposing to a negative intervention outcome. Overload of the medial compartment in slight varus can be reduced by applying the new KineSpring system, which can promote the best possible outcome of a biodegradable meniscal scaffold implantation, without producing biomechanical and anatomical alterations of the joint. This is the first case report on the combination of these hi-tech and bio-tech techniques...
October 2015: Joints
https://www.readbyqxmd.com/read/26894061/measuring-respiratory-pressures-with-mercury-manometer-in-low-economic-health-care-settings-an-analytical-study
#16
Prem Balaguru, Vishnupriya Hariharan, Rajajeyakumar Manivel, Madanmohan Trakroo
INTRODUCTION: Health care economics restricts many health centers from using hi-tech diagnostics equipment. Mercury manometers are used for calibration of pressure transducers. If standardized it would be a cost effective, simple alternative to transducers in low economic settings. AIM: To analyse the feasibility of mercury manometer usage in respiratory pressure measurement. MATERIALS AND METHODS: The experimental study was conducted with 30 healthy volunteers of age group 17-19 yrs...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26877996/questioning-the-spot-light-on-hi-tech-endodontics
#17
Jojo Kottoor, Denzil Albuquerque
No abstract text is available yet for this article.
February 2016: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/26827516/-a-new-light-on-professional-fitness-expertise-of-patients-with-highly-curable-arrhythmia-after-hi-tech-methods-of-treatment
#18
V B Simonenko, G G Hubulava, A L Chaplyuk, V I Steklov, D A Morozov, M V Emelyanenko
The peculiarities of a clinical course, results of pharmacological and interventional treatment in 447 patients with noncoronary cardiac arrhythmias were analyzed. A definition highly curable cardiac arrhythmia is introduced. The high efficiency and safety of the method of radiofrequency ablation in patients with highly curable cardiac arrhythmias that allows soldiers to leave the military service, as well as to enter military service under the contract. Proposed implementation of the control medical examination to conduct endocardial electrophysiological study and the subsequent medical examination to determine the category of fitness for military service not earlier than 6 months after surgery...
September 2015: Voenno-medit︠s︡inskiĭ Zhurnal
https://www.readbyqxmd.com/read/26827510/-hi-tech-center-of-outpatient-care-to-the-40th-anniversary-of-the-branch-n-6-of-the-vishnevsky-central-military-clinical-hospital-n-3
#19
A P Popov
The authors present the history of the branch N 6 of the Federal States Organization "the Vishnevsky Central Military Clinical Hospital N 3" of the Ministry of Defense of the Russian Federation, which dates back to November 1, 1974. Over the past years, organizational and staff structure; and the name of the clinic (45th central polyclinic, 45th central consultative-diagnostic polyclinic, 52nd Advisory Diagnostic Center of Defense) has repeatedly changed, but the core the work stays unchangeable--to continually improve patient care technology, to be the leader in the outpatient care for soldiers, reserve officers (retired), members of their families...
October 2015: Voenno-medit︠s︡inskiĭ Zhurnal
https://www.readbyqxmd.com/read/26597568/functional-properties-of-chitosan-built-nanohydrogel-with-enhanced-glucose-sensitivity
#20
Faheem Ullah, Muhammad Bisyrul Hafi Othman, Fatima Javed, Zulkifli Ahmad, Hazizan Md Akil, Siti Zalifah Md Rasib
A new approach to design multifunctional chitosan based nanohydrogel with enhanced glucose sensitivity, stability, drug loading and release profile are reported. Two approaches were followed for functionalization of chitosan based nanohydrogel with 3-APBA via EDC and 3-APTES. The effective functionalization, structure and morphology of Chitosan based IPN respectively were confirmed by FTIR, SEM and AFM. At physiological conditions, the glucose-induced volume phase transition and release profile of the model drug Alizarin Red with 1,2-diol structure (comparative to insulin as a drug as well as a dye for bio separation) were studied at various glucose concentrations, pH and ionic strengths...
February 2016: International Journal of Biological Macromolecules
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