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Uterine adhesions

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https://www.readbyqxmd.com/read/29454580/are-synechiae-a-complication-of-laparotomic-myomectomy
#1
Perrine Capmas, Anne-Gaelle Pourcelot, Hervé Fernandez
Laparotomic myomectomy is often the only realistic solution for symptomatic women with multiple or large myomas who wish to retain their fertility. The aim of this study was to document the rate of uterine synechiae and their associated risk factors after laparotomic myomectomy. This prospective observational study took place in a teaching hospital from May 2009 to June 2014. It included all women aged 18-45 years who had laparotomic myomectomies (without diagnostic hysteroscopy at the time of surgery) for myomas and a postoperative diagnostic office hysteroscopy 6-8 weeks later...
February 2, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29447856/laparoscopic-sacrohysteropexy-in-a-12-weeks-pregnant-woman
#2
Berna Haliloglu Peker, Erdin Ilter, Hakan Peker, Aygen Celik, Ali Gursoy, Onur Gunaldi
STUDY OBJECTIVE: To demonstrate laparoscopic sacrohysteropexy for a case of uterine prolapse in a 12 weeks and 3 days pregnant woman. To our knowledge, this is the first case of laparoscopic sacrohysteropexy performed at 12th weeks of gestation to be reported in literature. DESIGN: A step-by-step explanation of the surgical procedure (Canadian Task Force classification III) SETTING: Uterine prolapse is very rare condition manifesting in an estimated 10000 to 15000 pregnancies (1)...
February 12, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29439094/uterine-and-placental-distribution-of-selected-extracellular-matrix-ecm-components-in-the-dog
#3
Felix R Graubner, Alois Boos, Selim Aslan, Ibrahim Kücükaslan, Mariusz P Kowalewski
For many years, modifications of the uterine extracellular matrix (ECM) during gestation have not been considered as critical for successful canine (Canis lupus familiaris) pregnancy. However previous reports indicated an effect of free-floating blastocysts on the composition of the uterine ECM. Here, the expression of selected genes involved in structural functions, cell-to-cell communication and inhibition of matrix metalloproteinases were targeted utilizing qPCR and immunohistochemistry. We found that canine free-floating embryos affect gene expression of FN1, ECM1 and TIMP4...
February 9, 2018: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/29433563/therapeutic-effect-of-human-umbilical-cord-derived-mesenchymal-stem-cells-on-injured-rat-endometrium-during-its-chronic-phase
#4
Lu Zhang, Ying Li, Chun-Yi Guan, Shi Tian, Xiao-Dan Lv, Jian-Hui Li, Xu Ma, Hong-Fei Xia
BACKGROUND: Repair deficiency after endometrial injury is an important reason for intra-uterine adhesions, amenorrhea, and infertility in females. Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is effective in repairing the damaged endometrium. However, the possibility of using umbilical cord-derived MSCs (UC-MSCs) to treat endometrial injury is rarely reported. METHODS: Ethanol (95%) was injected into rat uterus to establish a model of endometrial injury...
February 13, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29432175/uterine-influences-on-conceptus-development-in-fertility-classified-animals
#5
Joao G N Moraes, Susanta K Behura, Thomas W Geary, Peter J Hansen, Holly L Neibergs, Thomas E Spencer
A major unresolved issue is how the uterus influences infertility and subfertility in cattle. Serial embryo transfer was previously used to classify heifers as high-fertile (HF), subfertile (SF), or infertile (IF). To assess pregnancy loss, two in vivo-produced embryos were transferred into HF, SF, and IF heifers on day 7, and pregnancy outcome was assessed on day 17. Pregnancy rate was substantially higher in HF (71%) and SF (90%) than IF (20%) heifers. Elongating conceptuses were about twofold longer in HF than SF heifers...
February 5, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29420398/sliding-sign-for-intra-abdominal-adhesion-prediction-before-repeat-cesarean-delivery
#6
Lior Drukker, Hen Y Sela, Orna Reichman, Ron Rabinowitz, Arnon Samueloff, Ori Shen
BACKGROUND: The sliding sign (the relative motion between the abdominal and uterine wall as assessed by ultrasonography) may help identify severe intra-abdominal adhesions before repeat cesarean delivery. METHODS: We conducted a prospective observational study of scheduled repeat cesarean deliveries. Using transabdominal ultrasonography, while the parturient breathed deeply, the ultrasonographer recorded a video clip in a sagittal plane lateral to the umbilicus...
February 5, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29416572/etiology-of-cesarean-uterine-scar-defect-niche-detailed-critical-analysis-of-hypotheses-and-prevention-strategies-and-peritoneal-closure-debate
#7
REVIEW
Shashikant L Sholapurkar
There is an increasing incidence of cesarean scar (CS) defect/niche and its sequelae, probably not entirely explained by better diagnosis or rising cesarean rate. Discussion of possible etiological factors has received scant attention but would be important to formulate preventive strategies. Meaningful informative studies on long-term sequelae of cesarean section are very difficult and none are available for causation of CS defect. Hence, it is crucial to identify key areas in etiology of CS defect for focused research...
March 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29391675/use-of-hysteroscopy-in-abnormal-uterine-bleeding-an-edge-over-histopathological-examination
#8
Parul Sinha, Nidhi Yadav, Uma Gupta
Purpose of the Study: To assess the efficacy of hysteroscopy in diagnosis of AUB. Method: A total of 56 women in reproductive and peri-menopausal age group (20-50 years) with complaints of abnormal uterine bleeding were enrolled in the study. All the patients underwent hysteroscopic examination followed by biopsy/histopathological evaluation. Hysteroscopic findings were compared against histopathological findings. Sensitivity, specificity, PPV, NPV and accuracy of hysteroscopy were calculated...
February 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29386988/clinical-characteristic-and-intraoperative-findings-of-uterine-perforation-patients-in-using-of-intrauterine-devices-iuds
#9
Xin Sun, Min Xue, Xinliang Deng, Yun Lin, Ying Tan, Xueli Wei
Background: Intrauterine devices (IUDs) are the most popular form of contraception used worldwide; however, IUD is not risk-free. IUD migrations, especially uterine perforations, were frequently occurred in patients. The aim of this study was to investigate the clinical characteristics and intraoperative findings in patients with migrated IUDs. Results: 29 cases of uterine perforation associated with migrated IUDs and 69 control patients were followed between January 2008 to March 2015...
2018: Gynecological Surgery
https://www.readbyqxmd.com/read/29382566/overexpression-of-the-14-3-3%C3%AE-protein-in-uterine-leiomyoma-cells-results-in-growth-retardation-and-increased-apoptosis
#10
Qi Shen, Xiaoli Hu, Lulu Zhou, Shuangwei Zou, Lu-Zhe Sun, Xueqiong Zhu
Protein 14-3-3γ was significantly reduced in human uterine leiomyoma compared to the adjacent normal myometrium tissue. To investigate the possible link between the reduced 14-3-3γ expression and uterine leiomyoma growth, we have overexpressed 14-3-3γ protein in uterine leiomyomal cells and its effects on cell proliferation and apoptosis were analyzed. Over-expression of 14-3-3γ was achieved by transducing into two types of uterine leiomyoma cells (primary culture cells and immortal stem cells) with a 14-3-3γ expressing adenovirus vector...
January 27, 2018: Cellular Signalling
https://www.readbyqxmd.com/read/29379666/could-the-female-to-male-transgender-population-be-donor-candidates-for-uterus-transplantation
#11
Murat Api, Ayşen Boza, Mehmet Ceyhan
Objective: To evaluate the eligibility of female-to-male (FtM) transgender people as donor candidates with regard to histologic, surgical, and social aspects. Materials and Methods: In this prospective cohort study, 31 FtM transgender people underwent standard hysterectomy and bilateral salpingo-oophorectomy for gender reassignment upon their request. The pelvic viscera of the transgender people was intraoperatively observed and the histology of the removed uteri were evaluated for fertility capacity and procurement surgery...
December 2017: Turkish journal of obstetrics and gynecology
https://www.readbyqxmd.com/read/29371172/the-power-law-of-learning-in-transumbilical-single-port-laparoscopic-subtotal-hysterectomy
#12
Shu-Han You, Chen-Ying Huang, Hsuan Su, Chien-Min Han, Chyi-Long Lee, Chih-Feng Yen
STUDY OBJECTIVE: To analyze the surgical outcomes and learning curve of transumbilical single-port laparoscopic subtotal hysterectomy which requires sutures of the cervical stump. DESIGN: Prospective observational study (Canadian Task Force Classification II-2). SETTING: University-affiliated center. PATIENTS: From the first (July 2012) and consecutive patients of benign uterine disease scheduled for subtotal hysterectomy till October 2013...
January 22, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29371171/simplified-laparoscopic-sacrohysteropexy
#13
Haider Jan, Vishalli Ghai, Ranee Thakar
STUDY OBJECTIVE: To demonstrate a simplified technique of performing a laparoscopic sacrohysteropexy for uterine prolapse DESIGN: Technical video demonstrating simplified method of a laproscopic sacrohysteropexy (Canadian Task force classification level III). SETTING: Benign gynaecology department at a University Hospital. INTERVENTION: A 38-year old woman with grade 3 uterine descent presented requesting surgical management for symptomatic prolapse...
January 22, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29358306/park7-regulates-inflammation-induced-pro-labour-mediators-in-myometrial-and-amnion-cells
#14
Ratana Lim, Gillian Barker, Martha Lappas
Preterm birth is a prevalent cause of neonatal deaths worldwide. Inflammation has been implicated in spontaneous preterm birth involved in the processes of uterine contractility and membrane rupture. Parkinson protein 7 (PARK7) has been found to play an inflammatory role in non-gestational tissues. The aims of this study were to determine the expression of PARK7 in myometrium and fetal membranes with respect to term labour onset and to elucidate the effect of PARK7 silencing in primary myometrium and amnion cells on pro-inflammatory and pro-labour mediators...
February 2018: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/29354487/laparoscopic-extracorporeal-surgery-performed-with-a-fixation-device-for-adnexal-masses-complicating-pregnancy-report-of-two-cases
#15
Hanako Kasahara, Iwaho Kikuchi, Aya Otsuka, Yoko Tsuzuki, Michio Nojima, Koyo Yoshida
The potential complications associated with an adnexal mass discovered during early pregnancy call for surgical treatment. Ideally, surgery is performed after gestational week 12, but uterine expansion after the first trimester makes surgery difficult. We report two pregnancies complicated by adnexal masses for which we used an organ fixation device for safe performance of single-site umbilical laparoscopic surgery. Pelvic magnetic resonance imaging depicted a dichorionic, diamniotic twin pregnancy and 60-mm right adnexal mass in the first patient and bilateral adnexae in the second...
December 26, 2017: World Journal of Methodology
https://www.readbyqxmd.com/read/29338827/risk-factors-of-intrauterine-adhesion-after-hysteroscopic-resection-of-endometrial-polyps
#16
Li Su, Lan You, Hong Ping Huang
Objective To analyze the risk factors of intrauterine adhesion (IUA) after hysteroscopic resection of endometrial polyps. Methods Totally 359 patients undergoing hysteroscopic resection of endometrial polyps from January 2013 to December 2016 were enrolled in this study. The clinical data of IUA group and non-IUA group were compared. Univariate analysis was performed to identify the risk factors of IUA,and multivariate Logistic regression analysis was further performed to get the independent risk factors. Results Of these 359 patients,IUA occured after operation in 56 patients (15...
December 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/29330113/runt-related-transcription-factor-1-runx1-deficiency-attenuates-inflammation-induced-pro-inflammatory-and-pro-labour-mediators-in-myometrium
#17
Martha Lappas
Identifying new targets that regulate myometrial activation are required to develop effective treatments to stop preterm labor. Inflammation, which can be induced by sterile or infective insults, plays a role in initiating and maintaining uterine contractions. Several high throughput transcription screening studies have identified an upregulation of runt-related transcription factor 1 (RUNX1) mRNA expression in myometrium with labor. The role of RUNX1 in labor, however, is not known. We report increased RUNX1 during late gestation which was further augmented in labor, suggesting that RUNX1 may be involved in the transition of the myometrium from a quiescent into a contractile state in preparation for labor...
January 9, 2018: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/29310409/analysis-of-diagnosis-and-treatment-of-complicated-cervical-severe-adhesion-atresia-after-removal-of-endometrial-stromal-nodule-a-case-report
#18
Rui Zhang, Pei Gu, Qi Liu, Bin Li, Wenpei Bai
RATIONALE: Endometrial stromal nodule (ESN) is a rare benign endometrial stroma tumor.Experiences are helpful for avoiding and treating similar postoperative complications (cervical adhesions and atresia). PATIENT CONCERNS: When appearing in the cervical, this tumor can easily lead to complications after the surgical resection. The diagnosis and postsurgery complication of a young woman's ESN was reported here. DIAGNOSES: The postoperative pathological diagnosis was ESN...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29297842/sterilization-of-hybrid-marmoset-callithrix-sp-females-an-evaluation-of-two-surgical-methods
#19
Fábio Ferreira de Queiroz, Giane Chaves Kristosch, Flávio Landim Soffiati, Mônica Jorge Luz, André Lacerda de Abreu Oliveira, Tânia Ribeiro Junqueira Borges, Carlos Ramón Ruiz Miranda, Leonardo Serafim da Silveira
Population control techniques, either permanent or reversible, are important tools for the management of wildlife in captive and natural environments. Among these, surgical sterilization provides a permanent solution to unwanted reproduction. Surgical techniques can differ in their invasiveness and in the subsequent effect on behavior and physiology. For social animals, techniques that preserve gonads, such as vasectomy for males and ligation of uterine tubes for females, may be preferred because they maintain important physiology that influences behavior...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29288978/expression-and-function-of-muc1-in-uterine-tissues-during-early-pregnancy-in-sheep-after-natural-oestrous-or-artificially-induced-oestrous
#20
Xiangguo Wang, Boyang Zhu, Shanhui Xiong, Xihui Sheng, Xiaolong Qi, Qizhen Huang, Chaolei Chen, Yong Guo, Hemin Ni
Mucin 1 (MUC1), a cell surface glycoprotein, is expressed mainly in the endometrial luminal epithelium (LE) and glandular epithelium (GE) of the endometrium in many mammalian species including mice, rats, pigs, sheep, horses and humans during various stages of a menstrual or oestrous cycle, where it plays an important role in embryo implantation and placentation. However, the expression and function of MUC1 in uterine tissues during early pregnancy in sheep after artificially-induced oestrous is not known. Therefore, we investigated the expression and function of MUC1 in the early pregnant and non-pregnant uterine tissues of sheep with natural oestrous or artificially-induced oestrous on days 10, 12, 14, 16 and 18 of the cycle by in situ hybridization, quantitative real-time polymerase chain reaction, immunohistochemical staining and western blotting methods...
December 20, 2017: Theriogenology
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