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https://www.readbyqxmd.com/read/28214117/evaluating-carbon-fluxes-of-global-forest-ecosystems-by-using-an-individual-tree-based-model-forcchn
#1
Jianyong Ma, Herman H Shugart, Xiaodong Yan, Cougui Cao, Shuang Wu, Jing Fang
The carbon budget of forest ecosystems, an important component of the terrestrial carbon cycle, needs to be accurately quantified and predicted by ecological models. As a preamble to apply the model to estimate global carbon uptake by forest ecosystems, we used the CO2 flux measurements from 37 forest eddy-covariance sites to examine the individual tree-based FORCCHN model's performance globally. In these initial tests, the FORCCHN model simulated gross primary production (GPP), ecosystem respiration (ER) and net ecosystem production (NEP) with correlations of 0...
February 14, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28208205/-social-determinants-of-subjective-health-life-satisfaction-and-absence-from-school-due-to-illness-among-adolescents-first-results-of-the-german-national-educational-panel-study-neps
#2
Kristina Heilmann, Janina Bräsen, Max Herke, Matthias Richter, Katharina Rathmann
The aim of this study is to examine the impact of social determinants on subjective health, life satisfaction and absence from school due to illness among adolescents in secondary schools, by using data from the German National Educational Panel Study (NEPS). Data was obtained from the National Educational Panel Study (NEPS). The sample included (n=5 790) 6(th) grade pupils in regular schools in 2011 (Starting Cohort 3, Wave 2). The socioeconomic background of adolescents was measured by pupils' school type as well as household income and parental education level...
February 16, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28202040/subcellular-localization-and-interactions-of-infectious-salmon-anemia-virus-isav-m1-and-nep-as-well-as-host-hsc70
#3
Wenting Zhang, Chengzhi Cai, Li Lin, Yizhi Jane Tao, Meilin Jin
BACKGROUND: Infectious salmon anemia virus (ISAV) is an important fish pathogen that causes high mortality in farmed Atlantic salmon. The ISAV genome consists of eight single-stranded, negative-sense RNA segments. The six largest segments contain one open reading frame (ORF) each, and encode three polymerase proteins, nucleoprotein, fusion protein, and hemagglutinin esterase protein. The two smallest segments contain more than one ORF each. The segment 7 encodes non-structural protein 1 (NS1) and nuclear export protein (NEP), while segment 8 encodes matrix protein 1 and 2 (M1 and M2)...
February 15, 2017: Virology Journal
https://www.readbyqxmd.com/read/28188955/increased-podocyturia-in-pregnant-women-compared-to-non-pregnant-women
#4
Itsuko Furuta, Tianyue Zhai, Takeshi Umazume, Satoshi Ishikawa, Kinuko Nakagawa, Rina Akaishi, Takahiro Yamada, Mamoru Morikawa, Hisanori Minakami
AIM: Hyperfiltration is a cause of podocyturia and occurs physiologically in the kidney of pregnant women. Podocyturia is increased in preeclamptic pregnancies, but it is unclear whether there is also any increase in uncomplicated pregnancies. This study was performed to examine whether podocyturia and urine aquaporin 2 mRNA expression are increased in healthy pregnant women (PW) compared to healthy non-pregnant women (NPW). METHODS: Eleven urines obtained from 11 NPW and longitudinal 76 urines from 40 PW with uncomplicated pregnancies (median number [range] of urine samples/person, 2 [1 - 3]) were studied...
February 11, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28188358/protective-effect-of-valproic-acid-in-streptozotocin-induced-sporadic-alzheimer-s-disease-mouse-model-possible-involvement-of-the-cholinergic-system
#5
Mirna Ezzat Sorial, Nesrine Salah El Dine El Sayed
Sporadic Alzheimer's disease (SAD) is a slowly progressive neurological disorder that is the most common form of dementia. Cholinergic system dysfunction and amyloid beta formation are the two main underlying pathological mechanisms for the disease development. In recent studies, insulin receptor desensitization and disturbances in the downstream effects of insulin receptor signaling were observed in the brains of Alzheimer's patients. Currently, intracereberoventricular (ICV) injection of streptozotocin (STZ) is found to induce behavioral, neurochemical, and structural alterations in animals resembling those found in SAD patients...
February 10, 2017: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/28174624/sex-differences-in-the-aging-pattern-of-renin-angiotensin-system-serum-peptidases
#6
A Fernández-Atucha, A Izagirre, A B Fraile-Bermúdez, M Kortajarena, G Larrinaga, P Martinez-Lage, E Echevarría, J Gil
BACKGROUND: Serum peptidases, such as angiotensin-converting enzyme (ACE), angiotensin-converting enzyme-2 (ACE2), neutral endopeptidase (NEP), aminopeptidase N (APN), and aminopeptidase A (APA), are important elements of the renin-angiotensin system (RAS). Dysregulation of these enzymes has been associated with hypertension and cardiovascular risk. In the present study, serum activities of RAS peptidases were analyzed to evaluate the existence of sexual differences, with a possible different pattern in pre- and post-andropausal/post-menopausal participants...
2017: Biology of Sex Differences
https://www.readbyqxmd.com/read/28161985/reliability-of-the-english-version-of-the-paindetect-questionnaire
#7
B Tampin, T Bohne, M Callan, M Kvia, A Melsom Myhre, E C Neoh, C Bharat, H Slater
BACKGROUND: The painDETECT questionnaire (PD-Q) has been used widely for the identification of neuropathic pain (NeP); however, the reliability of the English version of the PD-Q has never been investigated. OBJECTIVE: This study aimed to determine the reliability of the PD-Q pre- (T0) and immediately post- (T1) clinical consultation and at one-week follow-up (T2). METHODS: We recruited 157 patients attending a Neurosurgery Spinal Clinic and Pain Management Department...
February 5, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28161823/phylogeography-of-littorina-sitkana-in-the-northwestern-pacific-ocean-evidence-of-eastward-trans-pacific-colonization-after-the-last-glacial-maximum
#8
Noriko Azuma, Nadezhda I Zaslavskaya, Tomoyasu Yamazaki, Takahiro Nobetsu, Susumu Chiba
We investigated genetic diversity and population structure of the Sitka periwinkle Littorina sitkana along the coastlines of the northwestern Pacific (NWP) to evaluate the possibility of trans-Pacific colonization of this species from the NWP to the northeastern Pacific (NEP) after the Last Glacial Maximum. We sampled L. sitkana from 32 populations in the NWP, and sequenced a region of the mitochondrial cytochrome b oxidase gene for population genetic analyses. The results were compared with those of previous reports from the NEP...
February 4, 2017: Genetica
https://www.readbyqxmd.com/read/28160817/under-recording-of-work-related-injuries-and-illnesses-an-osha-priority
#9
Kathleen M Fagan, Michael J Hodgson
INTRODUCTION: A 2009 Government Accounting Office (GAO) report, along with numerous published studies, documented that many workplace injuries are not recorded on employers' recordkeeping logs required by the Occupational Safety and Health Administration (OSHA) and consequently are under-reported to the Bureau of Labor Statistics (BLS), resulting in a substantial undercount of occupational injuries in the United States. METHODS: OSHA conducted a Recordkeeping National Emphasis Program (NEP) from 2009 to 2012 to identify the extent and causes of unrecorded and incorrectly recorded occupational injuries and illnesses...
February 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28160414/neuropathic-pain-assessment-with-the-paindetect-questionnaire-cross-cultural-adaptation-and-psychometric-evaluation-to-hindi
#10
Kapil Gudala, Babita Ghai, Dipika Bansal
OBJECTIVE: The contribution of neuropathic pain (NeP) in chronic pain conditions is increasingly emphasized with the development of multiple questionnaire-based measurement scales. The painDETECT questionnaire (PDQ) is a frequently used self-reported outcome measure to assess NeP in patients with chronic pain conditions in research and regular clinical practice. The aim of the study was to translate and cross-culturally adapt the PDQ into Hindi (Hi-PDQ) for use in India and to investigate its psychometric properties...
February 3, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28156496/influence-of-early-phase-clinical-trial-enrollment-on-patterns-of-end-of-life-care-for-children-with-advanced-cancer
#11
Chalinee Monsereenusorn, Clement Ma, Hasan Al-Sayegh, Joanne Wolfe, Carlos Rodriguez-Galindo
: 151 Background: Early phase clinical trials are critical to enhancing therapies for children with advanced cancer. However, trial enrollment may intensify end-of-life (EOL) care. We evaluated patterns of EOL care for patients at a large cancer center. METHODS: Single-center, retrospective cohort study of pediatric oncology patients, ages 6 months-21 years, who died in 2010-2014. We queried electronic medical records to assess frequencies of medical procedures (e...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28145459/eddy-covariance-and-biometric-measurements-show-that-a-savanna-ecosystem-in-southwest-china-is-a-carbon-sink
#12
Xuehai Fei, Yanqiang Jin, Yiping Zhang, Liqing Sha, Yuntong Liu, Qinghai Song, Wenjun Zhou, Naishen Liang, Guirui Yu, Leiming Zhang, Ruiwu Zhou, Jing Li, Shubin Zhang, Peiguang Li
Savanna ecosystems play a crucial role in the global carbon cycle. However, there is a gap in our understanding of carbon fluxes in the savanna ecosystems of Southeast Asia. In this study, the eddy covariance technique (EC) and the biometric-based method (BM) were used to determine carbon exchange in a savanna ecosystem in Southwest China. The BM-based net ecosystem production (NEP) was 0.96 tC ha(-1) yr(-1). The EC-based estimates of the average annual gross primary productivity (GPP), ecosystem respiration (Reco), and net ecosystem carbon exchange (NEE) were 6...
February 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28130141/starch-based-xerogels-effect-of-acetylation-on-physicochemical-and-rheological-properties
#13
Chinwe U Kemas, Ndidi C Ngwuluka, Nelson A Ochekpe, Elijah I Nep
This study was aimed at evaluating the physicochemical and rheological properties of starch-based xerogels. The starch from the shoots of Borassus aethiopium was physically modified by xerogelization, and chemically by acetylation, and combination of acetylation and xerogelization. The solubility, swelling and syneresis of the starches were determined by gravimetric techniques. Evaluation of the native starch and derivatives was done using microscopy, Fourier transform infra-red (FTIR), x-ray diffractometry (XRD), and (1)H NMR spectroscopy...
January 24, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28123645/dynamic-alteration-of-neprilysin-and-endothelin-converting-enzyme-in-age-dependent-appswe-ps1de9-mouse-model-of-alzheimer-s-disease
#14
Li Zhou, Jianxu Liu, Dong Dong, Chunsheng Wei, Rui Wang
Imbalance of Aβ production and Aβ removal leads to Aβ accumulation. Aβ degrading enzyme (including neprilysin-NEP, endothelin converting enzyme-ECE) as a therapeutic strategy for lowering brain Aβ deposition has attracted increasing attention. In this study, we investigated alteration of age and region-dependent in APP/PS1 double transgenic mice (3, 6, 9, 12 months) and their age-matched wild type mice including the ability of spatial memory, Aβ deposits, the protein expression, location and activity of NEP and ECE...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/28113838/locality-sensitive-deep-learning-for-detection-and-classification-of-nuclei-in-routine-colon-cancer-histology-images
#15
Korsuk Sirinukunwattana, Shan Raza, Yee-Wah Tsang, David Snead, Ian Cree, Nasir Rajpoot
Detection and classification of cell nuclei in histopathology images of cancerous tissue stained with the standard hematoxylin and eosin stain is a challenging task due to cellular heterogeneity. Deep learning approaches have been shown to produce encouraging results on histopathology images in various studies. In this paper, we propose a Spatially Constrained Convolutional Neural Network (SC-CNN) to perform nucleus detection. SC-CNN regresses the likelihood of a pixel being the center of a nucleus, where high probability values are spatially constrained to locate in the vicinity of the center of nuclei...
February 4, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28109942/effect-of-pulmonary-rehabilitation-on-tidal-expiratory-flow-limitation-at-rest-and-during-exercise-in-copd-patients
#16
Elpida P Theodorakopoulou, Sofia-Antiopi Gennimata, Maria Harikiopoulou, Georgios Kaltsakas, Anastasios Palamidas, Antonia Koutsoukou, Charis Roussos, Epameinondas N Kosmas, Petros Bakakos, Nickolaos G Koulouris
We hypothesized that severe COPD patients who present with the disadvantageous phenomenon of Expiratory Flow Limitation (EFL) may benefit as COPD patients without EFL do after implementation of a Pulmonary Rehabilitation (PR) program. Forty-two stable COPD patients were studied at rest and during exercise. EFL and dynamic hyperinflation (DH) were documented using the negative expiratory pressure (NEP) technique and inspiratory capacity (IC) maneuvers, respectively. Patient centered outcomes were evaluated by the Saint-George's Respiratory Questionnaire (SGRQ) and the mMRC dyspnea scale...
January 18, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28107599/the-prevalence-and-impact-of-chronic-neuropathic-pain-on-daily-and-social-life-a-nationwide-study-in-a-japanese-population
#17
S Inoue, T Taguchi, T Yamashita, M Nakamura, T Ushida
BACKGROUND: This study marks the first epidemiological evaluation of the prevalence and burden of chronic neuropathic pain (NeP) in an Asian population. The objective of this nationwide cross-sectional study was to identify the characteristics of individuals with NeP, detect the NeP features that affect their quality of life (QOL), and demonstrate the negative effects of NeP on social and daily living as well as comorbidities including depression, anxiety and sleep disorders. METHODS: We mailed a cross-sectional, population-based epidemiological survey to a random nationwide sample of 10,000 Japanese adults over 20 years old...
January 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28104434/effects-of-human-opiorphin-on-food-intake-and-water-intake-in-mice-following-central-administration
#18
Yong Chen, Xiao-Zhu Tian, Lu Bai, Ze-Qi Liu, Xing-Peng Xiao, Pu Liu, Xiang-Kai Li
Human opiorphin plays an important pharmacological functions in rats or mice. The present study was performed to investigate effects and underlying mechanism of central injected opiorphin on food intake and water intake in mice. Intracerebroventricularly (i.c.v.) administered opiorphin (5-20μg/kg) dose-dependently suppressed food intake in fasted mice, but had no influence on food intake in freely feeding mice. The cumulative food intake was significantly decreased at 60min after injection of 10 and 20μg/kg opiorphin and the food intake was significantly reduced during the 20-60min period after treatment...
January 16, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28094071/on-nephrectomy-for-treating-metastatic-renal-cell-carcinoma
#19
C González-Ruiz de León, P Pellejero-Pérez, A Quintás-Blanco, J García-Rodríguez, C Álvarez-Fernández, J M Fernández-Gómez
INTRODUCTION: Systemic treatment for metastatic renal cell carcinoma (mRCC) has changed with the new therapies, and it is not clear if nephrectomy (NEP) has a survival benefit in this kind of patients. OBJECTIVE: To investigate if NEP associated to systemic treatment improves overall survival (OS) and progression-free survival (PFS). MATERIAL AND METHODS: A retrospective, observational, descriptive study of 45 patients with diagnosis of mRCC between 2006-2014...
January 13, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28076404/combined-inhibition-of-the-renin-angiotensin-system-and-neprilysin-positively-influences-complex-mitochondrial-adaptations-in-progressive-experimental-heart-failure
#20
Laura Grois, Julian Hupf, Jörg Reinders, Josef Schröder, Alexander Dietl, Peter M Schmid, Carsten Jungbauer, Markus Resch, Lars S Maier, Andreas Luchner, Christoph Birner
BACKGROUND: Inhibitors of the renin angiotensin system and neprilysin (RAS-/NEP-inhibitors) proved to be extraordinarily beneficial in systolic heart failure. Furthermore, compelling evidence exists that impaired mitochondrial pathways are causatively involved in progressive left ventricular (LV) dysfunction. Consequently, we aimed to assess whether RAS-/NEP-inhibition can attenuate mitochondrial adaptations in experimental heart failure (HF). METHODS AND RESULTS: By progressive right ventricular pacing, distinct HF stages were induced in 15 rabbits, and 6 animals served as controls (CTRL)...
2017: PloS One
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