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https://www.readbyqxmd.com/read/27912892/-mesocolic-excision-for-colonic-adenocarcinoma
#1
REVIEW
Clotilde Debove, Jérémie H Lefèvre, Yann Parc
On the same principle than total mesorectal excision in rectal cancer, the effect of complete mesocolic excision on short and long-term outcomes is actually evaluated for colonic adenocarcinoma. This method, usually performed for left colectomy, offers a surgical specimen of higher quality, with a larger number of lymph nodes harvested. For right colectomy, surgical specifications make it less common complete mesocolic excision and conventional surgery offer comparable outcomes, as regards to postoperative morbidity and mortality rates...
November 29, 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27901281/robotic-surgery-for-rectal-cancer-with-lateral-lymph-node-dissection
#2
T Watanabe, K Hata
No abstract text is available yet for this article.
December 2016: British Journal of Surgery
https://www.readbyqxmd.com/read/27895680/the-role-of-interstitial-brachytherapy-in-the-management-of-primary-radiation-therapy-for-uterine-cervical-cancer
#3
Naoya Murakami, Kazuma Kobayashi, Tomoyasu Kato, Satoshi Nakamura, Akihisa Wakita, Hiroyuki Okamoto, Satoshi Shima, Keisuke Tsuchida, Tairo Kashihara, Ken Harada, Kana Takahashi, Rei Umezawa, Koji Inaba, Yoshinori Ito, Hiroshi Igaki, Jun Itami
PURPOSE: The aim of this study was to report the clinical results of uterine cervical cancer patients treated by primary radiation therapy including brachytherapy, and investigate the role of interstitial brachytherapy (ISBT). MATERIAL AND METHODS: All consecutive uterine cervical cancer patients who were treated by primary radiation therapy were reviewed, and those who were treated by ISBT were further investigated for clinical outcomes and related toxicities. RESULTS: From December 2008 to October 2014, 209 consecutive uterine cervical cancer patients were treated with primary radiation therapy...
October 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27888300/analysis-of-local-recurrences-after-transanal-endoscopic-microsurgery-for-low-risk-rectal-carcinoma
#4
Theodor Junginger, Ursula Goenner, Mirjam Hitzler, Tong T Trinh, Achim Heintz, Wilfried Roth, Maria Blettner, Daniel Wollschlaeger
AIM: Rates of local recurrence (LR) after transanal endoscopic microsurgery (TEM) for rectal carcinoma vary; the reasons remain unclear. We analyzed LR after TEM for low-risk pT1 (G1/2/X, L0/X) rectal carcinoma to investigate the influence of completeness of resection and occult lymph node metastasis on risk of LR. METHOD: LR location and stage, completeness of resection of primary carcinoma (minimal distance between tumor and resection line ≤1 mm vs >1 mm), and incidence of involved lymph nodes in resected LR specimens were collected, and tumor characteristics of LR were compared with primary carcinoma...
November 25, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27884204/lateral-pelvic-lymph-node-dissection-after-neoadjuvant-chemo-radiation-for-preoperative-enlarged-lateral-nodes-in-advanced-low-rectal-cancer-study-protocol-for-a-randomized-controlled-trial
#5
Mingtian Wei, Qingbin Wu, Chuanwen Fan, Yan Li, Xiangzheng Chen, Zongguang Zhou, Junhong Han, Ziqiang Wang
BACKGROUND: Lateral lymph node (LLN) metastasis is a major cause of local recurrence of advanced rectal cancer. Although there is much controversy between Western and Eastern countries on whether lateral pelvic lymph node dissection (LLND) or neoadjuvant chemo-radiation (nCRT) is preferable for the treatment of LLN metastases, existing retrospective cohorts mainly focus on all middle/low advanced rectal cancer patients, not the specific individuals with suspicion of LLN metastases. The aim of this trial is to assess the efficacy and safety of LLND for rectal cancer patients with suspicion of LLN metastases...
November 25, 2016: Trials
https://www.readbyqxmd.com/read/27881187/class-solutions-for-sabr-vmat-for-high-risk-prostate-cancer-with-and-without-elective-nodal-irradiation
#6
Sarah O S Osman, Prakash Jeevanandam, Nithya Kanakavelu, Denise M Irvine, Ciara A Lyons, Suneil Jain, Alan R Hounsell, Conor K McGarry
BACKGROUND: The purpose of this study is to find the optimal planning settings for prostate SABR-VMAT for high-risk prostate cancer patients irradiated to prostate only (PO) or prostate and pelvic lymph nodes (PPLN). METHODS: For 10 patients, plans using 6MV flattened, flattening-filter-free (FFF) 6MV (6 F) and FFF 10MV (10 F) photon beams with full and partial arc arrangements were generated and compared. The prescribed dose was 40Gy to the prostate with 25Gy to the PLN in 5 fractions...
November 24, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27872975/identification-of-recurrence-predictive-indicators-in-stage-i-colorectal-cancer
#7
Jun Ho Lee, Jong Lyul Lee, In Ja Park, Seok-Byung Lim, Chang Sik Yu, Jin Cheon Kim
BACKGROUND: Patients with stage I colorectal cancer (CRC) rarely experience recurrences; therefore, few risk factors for recurrence are known. This study was designed to evaluate oncologic outcomes of patients with stage I CRC and to identify risk factors for recurrence after curative surgery. METHODS: A retrospective cohort of 860 patients from a single institution who underwent curative surgery for stage I CRC between July 1995 and June 2010 was enrolled. Patients who were diagnosed with hereditary, synchronous, or metachronous cancer and those who received preoperative chemoradiotherapy were excluded...
November 21, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27871166/traumatic-neuroma-at-the-inferior-mesenteric-artery-stump-after-rectal-cancer-surgery-a-case-report-and-literature-review
#8
Sung Mi Jeon, Jae Young Lee, Sun Ju Byeon
Traumatic neuroma results from regeneration attempts of the proximal end of an injured or severed nerve, resulting in a non-neoplastic nodular lesion. The lower extremity after amputation is the most common site, followed by the head and neck. Traumatic neuromas occurring in the abdomen, however, are rare. In the abdominal region, traumatic neuromas occur in the cystic duct stump and the common bile ducts as well as around the celiac trunk. This study reports a case of a 59-year-old man who presented with a traumatic neuroma arising at the stump of the inferior mesenteric artery after rectal cancer surgery...
November 25, 2016: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/27870592/robot-assisted-colectomy-for-left-sided-colon-cancer-comparison-of-reduced-port-and-conventional-multi-port-robotic-surgery
#9
Sung Uk Bae, Woon Kyung Jeong, Seong Kyu Baek
PURPOSE: The robotic single-port access plus one conventional robotic port, a reduced-port robotic surgery (RPRS) for left-sided colon cancer, can enable lymphovascular dissection using the wristed instrumentation and safe rectal transection through an additional port maintaining the cosmetic advantage of the single-port surgery. The aim of this study is to compare the clinicopathological outcomes between reduced-port and conventional multi-port robotic colectomy for left-sided colon cancer...
November 21, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27864695/adjuvant-chemotherapy-improves-overall-survival-of-rectal-cancer-patients-treated-with-neoadjuvant-chemoradiotherapy-regardless-of-pathologic-nodal-status
#10
Audrey S Kulaylat, Christopher S Hollenbeak, David B Stewart
BACKGROUND: After neoadjuvant chemoradiotherapy for rectal cancer, the interpretation of surgical pathology poses difficulties in deciding the need for adjuvant chemotherapy (AC). The aim of this study was to determine whether there is a survival benefit to providing AC in patients with node-negative disease on surgical pathology. METHODS: Patients with clinical stage II and III rectal adenocarcinoma who received neoadjuvant chemoradiation and definitive surgical resection from 2006 to 2012 were identified in the National Cancer Data Base...
November 18, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27863343/acrometastasis-following-colorectal-cancer-a-case-report-and-review-of-literature
#11
Kozar Agha, Khalid Akbari, Syed Husain Abbas, Simon Middleton, Daniel McGrath
INTRODUCTION: Colorectal cancer commonly metastasises to the liver, peritoneum and lungs. Bony metastases are uncommon in colorectal cancer and in particular metastases to the hands or feet (acrometastasis) are an extremely rare occurrence. CASE PRESENTATION: A 65-year-old male with a colonic malignancy underwent elective anterior resection. Intra-operatively he was found to have a pelvic collection necessitating an end colostomy. Histology confirmed complete Dukes B tumour excision with no evidence of lymph node metastases...
November 10, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27858861/laparoscopic-assisted-low-anterior-resection-for-advanced-rectal-cancer-in-a-kidney-transplant-recipient-a-case-report
#12
Zenan Xia, Weijie Chen, Ru Yao, Guole Lin, Huizhong Qiu
INTRODUCTION: Development of de novo malignancy has become a major cause of late mortality in solid organ transplant recipients. Surgery is currently the most important treatment of choice for transplant patients with resectable CRC. However, conventional open surgery represents a great risk to these high-risk patients. They seem to benefit more from laparoscopic surgery, based on the favorable oncological outcome and remarkable short-term advantages of this approach. PATIENT CONCERNS: In this study, we have reported a case of a 50-year-old man who had underwent kidney transplantation for 4 years...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27858839/prognostic-role-of-the-lymphocyte-to-monocyte-ratio-in-patients-undergoing-resection-for-nonmetastatic-rectal-cancer
#13
Qing-Bin Wu, Meng Wang, Tao Hu, Wan-Bin He, Zi-Qiang Wang
Lymphocyte-to-monocyte ratio (LMR) was associated with survival benefit in some types of cancer. The relationship between LMR and rectal cancer has not been investigated. We conducted a retrospective cohort study to assess the prognostic significance of LMR in patients with nonmetastatic rectal cancer. Patients with rectal cancer who underwent potentially curative resection between January 2009 and December 2013 were enrolled. The LMR was calculated from preoperative blood test by dividing the absolute lymphocyte counts by the absolute monocyte counts...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27826780/multicentre-propensity-score-matched-analysis-of-laparoscopic-versus-open-surgery-for-t4-rectal-cancer
#14
Nicola de'Angelis, Filippo Landi, Giulio Cesare Vitali, Riccardo Memeo, Aleix Martínez-Pérez, Alejandro Solis, Michela Assalino, Francesc Vallribera, Henry Alexis Mercoli, Jacques Marescaux, Didier Mutter, Frédéric Ris, Eloy Espin, Francesco Brunetti
BACKGROUND: The use of laparoscopy for advanced-stage rectal cancer remains controversial. This study aimed to compare the operative and oncologic outcomes of laparoscopic (LAR) versus open anterior rectal resection (OAR) for patients with pT4 rectal cancer. METHODS: This is a multicenter propensity score matching (PSM) study of patients undergoing elective curative-intent LAR or OAR for pT4 rectal cancer (TNM stage II/III/IV) between 2005 and 2015. RESULTS: In total, 137 patients were included in the analysis...
November 8, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27822086/danish-colorectal-cancer-group-database
#15
REVIEW
Peter Ingeholm, Ismail Gögenur, Lene H Iversen
AIM OF DATABASE: The aim of the database, which has existed for registration of all patients with colorectal cancer in Denmark since 2001, is to improve the prognosis for this patient group. STUDY POPULATION: All Danish patients with newly diagnosed colorectal cancer who are either diagnosed or treated in a surgical department of a public Danish hospital. MAIN VARIABLES: The database comprises an array of surgical, radiological, oncological, and pathological variables...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27819876/impact-of-postoperative-adjuvant-chemotherapy-following-long-course-chemoradiotherapy-in-stage-ii-rectal-cancer
#16
Jonathan M Loree, Hagen F Kennecke, Richard M Lee-Ying, Rachel A Goodwin, Erin D Powell, Patricia A Tang, Julie A Price Hiller, Michael M Vickers, Winson Y Cheung
OBJECTIVES: Use of adjuvant chemotherapy (AC) following neoadjuvant chemoradiation (nCRT) is controversial in rectal cancer (RC). We assessed a multi-institutional database to determine if there was benefit from AC for pathologic stage II RC patients and whether the addition of oxaliplatin to fluoropyrimidine (OXAC) therapy impacted outcomes. MATERIALS AND METHODS: We included patients who underwent nCRT and had pathologic stage II (ypT3/4 ypN0) tumors. Disease-free survival and overall survival were assessed...
November 4, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27819636/the-importance-of-preoperative-stadialization-of-rectal-cancer-using-multiparametric-mri-a-systematic-review
#17
Ferdinand Bauer
A correct preoperative stadialization of rectal carcinoma has a direct influence upon its therapeutic strategy, resulting in a significant improvement of the survival rate and life quality after the treatment. The therapeutic strategy refers to the option of undergoing or not preoperative radiochemotherapy before the total mesorectal excision (TME). The technical advances in the magnetic resonance domain makes possible the multiparametric examinations (mp MRI) with medical equipments (3T models are common) good enough to obtain images having an excellent quality, which allow a correct diagnosis of the local tumour spread...
2016: Chirurgia
https://www.readbyqxmd.com/read/27807725/unilateral-pelvic-side-wall-lymph-node-resection-for-rectal-cancer-a-review-of-the-anatomy
#18
Tian-Zhi Lim, Peter J Lee, Michael J Solomon, Ker-Kan Tan
BACKGROUND: The aim of this video is to highlight key safety and critical techniques employed during laparoscopic pelvic side-wall lymph node resection for rectal cancer. In addition, a review of the key pelvic side-wall anatomical structures will be included. METHODS: We report a case of a 50-year-old Chinese female who presented with per-rectal bleeding, with colonoscopy revealing a 1.5 cm moderately differentiated rectal adenocarcinoma 4 cm above the anorectal junction...
November 2, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27806332/the-survival-and-clinicopathological-differences-between-patients-with-stage-iiia-and-stage-ii-rectal-cancer-an-analysis-of-12-036-patients-in-the-seer-database
#19
Ben Huang, Shaobo Mo, Liang Zhu, Tianhong Xu, Guoxiang Cai
BACKGROUND: Stage IIIA rectal cancer has distinctive oncological features, including limited depth of intestinal wall invasion and early regional lymph node metastasis. We aim to compare survival outcomes and clinicopathological features for stage IIIA rectal cancer with those for stage II rectal cancer. METHOD: We analyzed patients with stage II or stage IIIA rectal cancer treated with surgery without receiving preoperative radiotherapy based on data from the US Surveillance, Epidemiology, and End Results (SEER) database between 1988 and 2003...
October 28, 2016: Oncotarget
https://www.readbyqxmd.com/read/27796635/clinically-node-negative-pathologically-node-positive-rectal-cancer-patients-who-did-not-receive-neoadjuvant-therapy
#20
Nouf Akeel, Nan Lan, Luca Stocchi, Meagan M Costedio, David W Dietz, Emre Gorgun, Matthew F Kalady, Georgios Karagkounis, Hermann Kessler, Feza H Remzi
PURPOSE: Neoadjuvant chemoradiotherapy is the preferred standard of care for clinical stages II-III rectal cancer. It is uncertain whether clinically node negative (cN-) tumors found to be pathologically stage III could be optimally treated with surgery alone and avoid adjuvant treatments. The aim of our study was to define the outcomes of such patients. METHODS: Patients undergoing radical surgery using total mesorectal excision (TME) techniques for rectal cancer (≤12 cm from the anal verge) with curative intent during 2000-2012 and found to have stage III disease on final pathology were identified from a prospectively maintained database...
October 27, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
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