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Cerebral hemmorrhage

D Sablot, J-F Cassarini, A Akouz, J-M Benejean, F Leibinger, X Faillie, E Vidry, X Ayrignac, S Castro, L Sinaya, J-L Bertrand, Y Garcia, B Arnoud, C Negre
INTRODUCTION: Intravenous recombinant tissue plasminogen activator (rt-PA) has approval for use despite of its authorization for treatment of ischemic stroke within the 3-hour time window in 2003, is rarely used in community hospital (CH). It therefore remains questionable if the positive results of the key studies conducted in specialized centers may be extended to community hospitals less specialized in the management of stroke. METHODS: We report the results of an observational cohort study including 39 patients treated with intravenous rt-Pa (according to the NINDS rt-PA stroke trail treatment protocol) at St Jean Hospital (Perpignan, France) between March 1, 2002 and August 31, 2005...
November 2006: Revue Neurologique
Robert D Henderson, David G Walker, Ken Mitchell, Stephan J Read
We present an unusual case that highlights a number of management dilemmas: the cause, investigation and treatment of subarachnoid hemmorrhage in patients iwth vascular connective tissue diseases; the further investigation of small aneurysms identified on CT angiography; and the difficulties associated with anticoagulation, mechanical cardiac valves and cerebral hemorrhage.
2004: Neurocritical Care
J E Brian, S Eleff, R W McPherson
Three patients are reported who suffered intracranial hemmorrhage during interventionally neuroradiology procedures. All had severe hypertension, cardiac arrhythmias and loss of consciousness. Immediate CT scan showed small amounts of blood in all patients. Arrhythmias were controlled with lidocaine. In two patients, the hypertension was treated only with barbiturates plus fentanyl and in the third with labetol and nitroprusside. In the patient treated with nitroprusside and one patient with barbiturate plus fentanyl a 14-20 min period of hemodynamic stability was followed by vasomotor collapse requiring intravenous vasopressor support...
March 1989: Journal of Neurosurgical Anesthesiology
C Oppenheim, Y Samson, D Dormont, S Crozier, R Manaï, G Rancurel, D Frédy, C Marsault
PURPOSE: Symptomatic hemorrhagic transformation is a severe complication of acute ischemic stroke which occurs at a higher frequency after thrombolysis. The present study was designed to analyze whether early DWI can be used for predicting the risk of hemorrhagic transformation with clinical worsening in MCA stroke patients. MATERIALS AND METHODS: Of 28 patients with a middle cerebral artery (MCA) infarct and proven MCA or carotid T occlusion on DWI and MR angiography performed within 14 hours after onset (mean 6...
March 2002: Journal of Neuroradiology. Journal de Neuroradiologie
V P Dhopesh, J O Greenberg, M M Cohen
Seven of eight patients had a clinical diagnosis other than brainstem hemorrhage before computed tomography (CT). Four were diagnosed as infarction, one as intracerebral hemmorrhage, one as hypertensive encephalopathy, and one as subdural hematoma. All survived except one, who died of pulmonary embolus. Although the yeild of posterior fossa lesions on CT is thought to be small, our experience indicates that CT is exceedingly valuable in demonstrating and localizing brainstem hemorrhage. The prognosis of brainstem hemorrhage appears to be better than reported in the literature...
October 1980: Journal of Computer Assisted Tomography
R Leblanc, W Feindel, L Yamamoto, J G Milton, M M Frojmovic
Acute vasospasm of the transclivally exposed basilar artery of anesthetised cats was produced by the subarachnoid injection of platelet-rich plasma (PRP) treated with enough adenosine diphosphate (ADP) to induce platelet aggregation and secretion. Vasorelaxation was produced by the topical application of the calcium antagonist verapamil. Changes in the internal diameter of the basilar artery were determined by measuring the blood column diameter from photomicrographs taken sequentially, at 5 minute intervals, through the operating microscope...
February 1984: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
J M Askey
Intracranial hemorrhage was the most serious hemorrhage as measured by death and disability, occurring during long-term anticoagulant drug therapy of 1,626 patients. Among 95 hemorrhagic episodes considered life-threatening or potentially crippling, 30 were intracranial and 56 were gastrointestinal. Over two-thirds of the patients with intracranial hemorrhage died, as against one-tenth of those with gastrointestinal hemorrhage. The incidence of intracranial hemorrhage is increased among hypertensive patients, but the results of a controlled study indicate that the incidence of intracranial hemorrhage is not affected by whether or not the hypertensive patient is receiving anticoagulant therapy...
January 1966: California Medicine
T Nakahara, N Nonaka, K Kinoshita, Y Matsukado
An episode of subarachnoid hemorrhage was seen on a 22-year-old married woman, which followed vaginal spotting and convulsive seizure. The neurological examination revealed bilateral papilledema, retinal hemorrhage, neck stiffness, Kernig's sign abducens paresis on the right. The chest X-ray film showed a spherical mass lesion in the right lung. The pelvic examination disclosed no pathological findings, however, HCG (human chorionic gonadotropin) in the urine increased significantly. Intracranial metastasis of chorioepithelioma was the tentative diagnosis at the admission and the right caroid angiography was performed, which demonstrated a fusiform aneruysm of the right middle cerebral artery beside arterial shift indicating a metastatic mass lesion in the parietal lobe...
September 1975: No Shinkei Geka. Neurological Surgery
S Noda
Adult mongrel dogs were used. The posterior communicating artery was punctured with a fine needle and subarachnoid hemorrhage was produced, which simulated aneurysmal rupture in human. The cerebral basal arteries were constricted remarkably after the puncture. However this vasospasm disappeared in about 60-120 minutes. After this restoration, the vessels began to be constricted again and reduced their diameter in greater degree with lapse of time. Effect of various drugs and sympathectomy on the experimental spasm induced by this method were studied utilizing the magnified vertebral angiography...
September 1975: No Shinkei Geka. Neurological Surgery
P M Saradzhishvili, V M Gabashvili
The authors studied 274 patients with ischemic and hemmorrhagical accidents which developed at night during sleep and awakening. A hypersensitivity of the carotid sinus was much more frequently seen in patients with ischemic accidents and was encountered not only in an extrasinus (massage), but in an intrasinus irritation (Walsalwa test) as well. The study also demonstrated significant cardio-inhibitive and vaso-depressive reactions, with an expressed asystolia and a drop in the arterial pressure. The authors express their opinion regarding the role of a developing bradycardia, asystolia, hypertension and a decrease in the postural tone in the genesis of ischemic accidents which may be due to a compression of the hypertensive carotid sinus...
1975: Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova
R Korobkin
Rapidly enlarging head circumference is a standard clinical sign of progressive hydrocephalus in an infant. Six neonates 29 to 36 weeks gestational age, with intraventricular hemorrhage, confirmed by ventricular tap, had head circumferences measured at intervals from birth. The sudden appearance of rapidly expanding head size, not associated with changing clinical status, occurred 9 to 20 days after the estimated time of hemorrhage in all of the infants. Air ventriculography within three days of abnormal acceleration of head circumference growth demonstrated moderately to severely dilated ventricles...
July 1975: Pediatrics
H Kasper, M Brodersen, R Schedel
Starting from clinical observations indicating a reduction in the stress ulcer rate by parenteral administration of high doses of vitamin A after burns, traumatic damage and surgical operations, the pattern of vitamin A, retinol-binding protein (RBP) and prealbumin (PA) concentrations in serum was studied in a number of patients with multiple traumas (group 1; n equals 32), cranial-cerebral lesions and postoperative conditions (group 2; n equals 27) and patients having undergone gynecologic operation (group 3; n equals 15); the results obtained were compared with the concentrations determined preoperatively and the normal values as reported in the literature...
December 1975: Acta Hepato-gastroenterologica
G I Eninia, E S Smeltere, R Ia Rundans
The study deals with the influence of Droperidol introduced intravenously in doses 2.5 mg on the REG indices of cerebral hemodynamics in patients with disorders of cerebral circulation. The achieved data indicate its mild hypotensive effect, an increase of the module of elasticity of the walls in large brain vessels along with a distinct decrease in the cerebral vascular resistance, as well as an improvement of the venous outflow of blood due to the influence of droperidol. The effect of this preparation appeared to be more expressed in patients with hemmorrhages into the brain and its membranes...
1978: Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova
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