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https://www.readbyqxmd.com/read/28227704/comparing-glucose-and-insulin-data-from-the-two-hour-oral-glucose-tolerance-test-in-metabolic-syndrome-subjects-and-marathon-runners
#1
Miguel Altuve, Gilberto Perpinan, Erika Severeyn, Sara Wong, Miguel Altuve, Gilberto Perpinan, Erika Severeyn, Sara Wong, Sara Wong, Gilberto Perpinan, Erika Severeyn
Glucose is the main energy source of the body's cells and is essential for normal metabolism. Two pancreatic hormones, insulin and glucagon, are involved in glucose home-ostasis. Alteration in the plasma glucose and insulin concentrations could lead to distinct symptoms and diseases, ranging from mental function impairment to coma and even death. Type 2 diabetes, insulin resistance and metabolic syndrome are typical examples of abnormal glucose metabolism that increase the risk for cardiovascular disease and mortality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226326/psoriasis-and-obesity
#2
Peter Jensen, Lone Skov
Psoriasis is a common chronic inflammatory skin disease with a complex pathogenesis consisting of a genetic component, immune dysfunction, and environmental factors. It is associated with numerous comorbidities including psoriatic arthritis, cardiovascular disease, metabolic syndrome, and obesity. Evidence suggests that obesity is a risk factor for incident psoriasis, aggravates existing psoriasis, and that weight reduction may improve the severity of psoriasis in overweight individuals. Excess body weight may interfere with the medical treatment used in psoriasis and adds to the cardiovascular risk profile in these patients, which underscores the importance of effective weight control regimens...
February 23, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28226308/preliminary-examination-of-metabolic-syndrome-response-to-motivational-interviewing-for-weight-loss-as-compared-to-an-attentional-control-and-usual-care-in-primary-care-for-individuals-with-and-without-binge-eating-disorder
#3
Rachel D Barnes, Jessica A Barber
Motivational interviewing (MI) treatment for weight loss is being studied in primary care. The effect of such interventions on metabolic syndrome or binge eating disorder (BED), both highly related to excess weight, has not been examined in primary care. This study conducted secondary analyses from a randomized controlled trial to test the impact of MI for weight loss in primary care on metabolic syndrome. 74 adult participants with overweight/obesity recruited through primary care were randomized to 12weeks of either MI, an attentional control, or usual care...
February 14, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/28226264/leukocyte-telomere-length-in-hispanic-schizophrenia-patients-under-treatment-with-olanzapine
#4
Nancy Monroy-Jaramillo, Yaneth Rodríguez-Agudelo, Luis Carlos Aviña-Cervantes, David L Roberts, Dawn I Velligan, Consuelo Walss-Bass
Different lines of evidence indicate that patients with schizophrenia (SZ) exhibit accelerated aging. Leukocyte telomere length (TL), an aging marker, is associated with age-related and chronic pathologies, including schizophrenia. We analyzed leukocyte TL in 170 SZ patients of Hispanic ancestry grouped based on antipsychotic treatment, compared to 126 matched controls. The group under treatment with atypical antipsychotics was further subdivided according to the risk of medication to cause metabolic syndrome (MetS)...
February 10, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28226031/evaluation-of-clinical-and-laboratory-markers-of-cardiometabolic-risk-in-overweight-and-obese-children-and-adolescents
#5
Heloísa Marcelina da Cunha Palhares, Adriana Paula da Silva, Daniela Cristina Silva Resende, Gilberto de Araújo Pereira, Virmondes Rodrigues, Maria de Fátima Borges
OBJECTIVE: This study analyzed the frequency of cardiometabolic risk markers and metabolic syndrome occurrence in overweight and obese children and adolescents. METHODS: The participants included 161 overweight (n=65) and obese (n=96) individuals aged between 5 and 19 years. Clinical markers were assessed (body mass index, body fat percentage, waist circumference, acanthosis, systolic and diastolic blood pressures, laboratory parameters [glucose, insulin, cholesterol (total and fractions) and triglyceride levels and homeostasis model assessment of insulin resistance (HOMA-IR) index] and leptin and adiponectin levels)...
January 1, 2017: Clinics
https://www.readbyqxmd.com/read/28225956/prevalence-of-metabolic-syndrome-in-patients-with-psoriasis-a-hospital-based-cross-sectional-study
#6
Danijela Milčić, Slavenka Janković, Sonja Vesić, Mirjana Milinković, Jelena Marinković, Andja Ćirković, Janko Janković
BACKGROUND: Emerging epidemiological evidence suggests independent associations between psoriasis and metabolic syndrome. Objectives: The aim of the study was to examine the prevalence of metabolic syndrome and its components in patients with psoriasis, and to assess which factors may predict metabolic syndrome in these patients. METHODS: A hospital-based, cross-sectional study with 244 psoriatic patients and 163 control subjects with skin diseases other than psoriasis was conducted at the Clinic of Dermatovenerology, Clinical Center of Serbia, Belgrade, from October 2011 to October 2012...
January 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28225880/the-role-of-oxidative-stress-on-the-pathophysiology-of-metabolic-syndrome
#7
Fabiane Valentini Francisqueti, Lidiana Camargo Talon Chiaverini, Klinsmann Carolo Dos Santos, Igor Otávio Minatel, Carolina Berchieri Ronchi, Artur Junio Togneri Ferron, Ana Lúcia A Ferreira, Camila Renata Corrêa
Metabolic syndrome (MetS) has a high prevalence around the world. Considering the components used to classify MetS, it is clear that it is closely related to obesity. These two conditions begin with an increase in abdominal adipose tissue, which is metabolically more active, containing a greater amount of resident macrophages compared to other fat deposits. Abdominal adiposity promotes inflammation and oxidative stress, which are precursors of various complications involving MetS components, namely insulin resistance, hypertension and hyperlipidemia...
January 1, 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28225861/predictors-of-subclinical-atherosclerosis-evaluated-by-carotid-intima-media-thickness-in-asymptomatic-young-women-with-type-1-diabetes-mellitus
#8
Rosane Kupfer, Manuella Rangel Larrúbia, Isabela Bussade, Joana Rodrigues Dantas Pereira, Giovanna A Balarini Lima, Marcio Antonio Epifanio, Claudio Domenico Sahione Schettino, Denise Prado Momesso
Objective: This study aimed to evaluate the occurrence and clinical predictors of subclinical atherosclerosis in asymptomatic, young adult women with type 1 DM. Subjects and methods: The study included 45 women with type 1 diabetes mellitus (DM) (aged 36 ± 9 years) who underwent carotid Doppler ultrasound evaluation to determine the carotid artery intima-media thickness (CIMT) and to assess the occurrence of carotid artery plaques. Insulin sensitivity was assessed by estimated glucose disposal rate (eGDR), and metabolic syndrome (MS) was defined by the World Health Organization criteria...
February 16, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225859/prevalence-of-metabolic-syndrome-in-pre-and-postmenopausal-women
#9
Ricardo de Marchi, Cátia Millene Dell'Agnolo, Tiara Cristina Romeiro Lopes, Angela Andréia França Gravena, Marcela de Oliveira Demitto, Sheila Cristina Rocha Brischiliari, Deise Helena Pelloso Borghesan, Maria Dalva de Barros Carvalho, Sandra Marisa Pelloso
Objective: The objective of this study was to determine the prevalence of metabolic syndrome (MS) and its components among pre- and postmenopausal women, as well as the association between menopausal status and MS. Materials and methods: A retrospective study was conducted at a reference cardiology outpatient clinic in a city located in Northwestern Paraná State, Brazil. A total of 958 medical records of symptomatic climacteric women evaluated between 2010 and 2014 were analyzed...
February 16, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225503/association-of-serum-ferritin-with-insulin-resistance-abdominal-obesity-and-metabolic-syndrome-in-korean-adolescent-and-adults-the-korean-national-health-and-nutrition-examination-survey-2008-to-2011
#10
Young Suk Shim, Min Jae Kang, Yeon Jeong Oh, Joon Woo Baek, Seung Yang, Il Tae Hwang
This study aimed to evaluate the associations of serum ferritin with insulin resistance indices, body fat mass/percentage, and all the components of metabolic syndrome (MetS), as well as the risk for MetS according to serum ferritin levels in Korean adolescents and adults.A total of 15,963 Korean males and females aged 16 to 80 years were analyzed using data from the Korean National Health and Nutrition Examination Survey, 2005 to 2011.The median serum ferritin concentration was 98.82 ng/mL for males and 38...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28224090/vitamin-d-deficiency-insufficiency-from-childhood-to-adulthood-insights-from-a-sunny-country
#11
REVIEW
Motti Haimi, Richard Kremer
Vitamin D is known to be a key regulator of bone metabolism and is associated with muscle strength. Vitamin D deficiency is widely prevalent worldwide. In adults, vitamin D deficiency has been implicated in numerous health conditions including osteoporosis, cancer, diabetes, and autoimmune diseases. Considerable changes have occurred in lifestyles and childhood activities in the past years. Studies have shown that the children population is at high risks of vitamin D deficiency. The objective of this study was to learn about the extent of vitamin D deficiency in children worldwide and especially in sunny country like Israel...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28224026/effect-of-helicobacter-pylori-on-metabolic-syndrome-parameters-in-diabetic-patients
#12
Jamshid Vafaeimanesh, Mohammad Bagherzadeh, Atefeh Mirzaei, Mahmoud Parham, Mohsen Norouzinia, Reza Vafaee
AIM: The aim of this study is to survey the effect of Helicobacter Pylori on metabolic syndrome parameters in diabetic patients. BACKGROUND: Helicobacter pylori (HP) infection is the most common infection in developing countries. Some studies showed the association between HP infection and insulin resistance. Insulin resistance is a major mechanism in the development of metabolic syndrome (MetS) and it is said that MetS is more prevalent among HP infected subjects...
December 2016: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/28223818/an-evidence-based-review-on-urate-lowering-treatments-implications-for-optimal-treatment-of-chronic-hyperuricemia
#13
REVIEW
Marilisa Bove, Arrigo Francesco Giuseppe Cicero, Maddalena Veronesi, Claudio Borghi
Several studies suggest that chronic hyperuricemia, the main precursor of gout, is involved in the pathogenesis of different systemic disorders that affect cardiovascular and renal systems, such as hypertension, obesity, hypercholesterolemia, atherosclerosis, metabolic syndrome, chronic heart failure, and chronic kidney disease. Recent epidemiological evidence has shown an increasing trend in the prevalence of hyperuricemia and gout in the Western world: a number of population-based studies estimate a prevalence of up to 21% for hyperuricemia and 1%-4% for gout...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28223816/prevalence-of-metabolic-syndrome-in-adolescents-living-in-mthatha-south-africa
#14
Morongwe Annah Sekokotla, Nandu Goswami, Constance Rufaro Sewani-Rusike, Jehu Erapu Iputo, Benedicta Ngwenchi Nkeh-Chungag
OBJECTIVE: Metabolic syndrome (MetS), defined as the clustering of three of five risk factors (hypertension, obesity, triglyceridemia, dyslipidemia and hyperglycemia), is being increasingly mentioned among children and adolescents despite there being no consensus on how it should be defined in this set of population. Furthermore, very few studies have focused on MetS in children and adolescents in sub-Saharan populations. This study, therefore, aimed at determining the prevalence of the MetS and contributing risk in adolescents living in Mthatha, South Africa...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28223722/to-screen-or-not-to-screen-celiac-antibodies-in-liver-diseases
#15
REVIEW
Janaína Luz Narciso-Schiavon, Leonardo Lucca Schiavon
Celiac disease (CD) is a systemic immune-mediated disorder triggered by dietary gluten in genetically predisposed individuals. The typical symptoms are anemia, diarrhea, fatigue, weight loss, and abdominal pain. CD has been reported in patients with primary sclerosing cholangitis, primary biliary cholangitis, autoimmune hepatitis, aminotransferase elevations, nonalcoholic fatty liver disease, hepatitis B, hepatitis C, portal hypertension and liver cirrhosis. We evaluate recommendations for active screening for CD in patients with liver diseases, and the effect of a gluten-free diet in these different settings...
February 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28223446/management-of-nonalcoholic-fatty-liver-disease-in-patients-with-type-2-diabetes-a-call-to-action
#16
REVIEW
Fernando Bril, Kenneth Cusi
Traditionally a disease of hepatologists, nonalcoholic fatty liver disease (NAFLD) has recently become a major concern for a broad spectrum of health care providers. Endocrinologists and those caring for patients with type 2 diabetes mellitus (T2DM) are at center stage, as T2DM appears to worsen the course of NAFLD and the liver disease makes diabetes management more challenging. However, the nature of this relationship remains incompletely understood. Although the increasing prevalence of NAFLD is frequently attributed to the epidemic of obesity and is often oversimplified as the "hepatic manifestation of the metabolic syndrome," it is a much more complex disease process that may also be observed in nonobese individuals and in patients without clinical manifestations of the metabolic syndrome...
March 2017: Diabetes Care
https://www.readbyqxmd.com/read/28223316/energy-metabolism-drives-myeloid-derived-suppressor-cell-differentiation-and-functions-in-pathology
#17
REVIEW
Antonio Sica, Laura Strauss
Over the last decade, a heterogeneous population of immature myeloid cells with major regulatory functions has been described in cancer and other pathologic conditions and ultimately defined as MDSCs. Most of the early work on the origins and functions of MDSCs has been in murine and human tumor bearers in which MDSCs are known to be immunosuppressive and to result in both reduced immune surveillance and antitumor cytotoxicity. More recent studies, however, suggest that expansion of these immature myeloid cells may be linked to most, if not all, chronic and acute inflammatory processes...
February 21, 2017: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/28222857/liver-fibrosis-assessed-with-transient-elastography-is-an-independent-risk-factor-for-ischemic-stroke
#18
Seung Up Kim, Dongbeom Song, Ji Hoe Heo, Joonsang Yoo, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang Joon Kim, Kwang-Hyub Han, Young Dae Kim
BACKGROUND AND AIMS: The relationship between liver fibrosis and the occurrence of ischemic stroke is unknown. We investigated the correlation between liver fibrosis assessed with transient elastography (TE) and the risk of ischemic stroke. METHODS: Between April 2013 and August 2014, patients with acute ischemic stroke and subjects who underwent a health check-up were included in the study. Liver fibrotic burden was assessed with TE in all participants. The degree of liver fibrosis was compared between groups by using various multiple logistic regression models and propensity-score matched analyses...
February 12, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28222635/serum-betatrophin-levels-are-increased-and-associated-with-insulin-resistance-in-patients-with-polycystic-ovary-syndrome
#19
Qinglan Qu, Dongmei Zhao, Fengrong Zhang, Hongchu Bao, Qiuhua Yang
Objective Betatrophin is a newly identified circulating protein that is significantly associated with type 2 diabetes mellitus (T2DM), adiposity, and metabolic syndrome. The aim of this study was to investigate whether betatrophin levels and polycystic ovary syndrome (PCOS) were associated. Methods Circulating betatrophin levels were measured in 162 patients with PCOS and 156 matched control females using specific enzyme-linked immunosorbent assay kits. Correlations between betatrophin levels and PCOS incidence as well as multiple key endocrine PCOS parameters were analyzed using multiple statistical methods...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28222379/increased-static-and-decreased-capacity-oxidation-reduction-potentials-in-plasma-are-predictive-of-metabolic-syndrome
#20
Gerd Bobe, Tora J Cobb, Scott W Leonard, Savinda Aponso, Christopher B Bahro, Dipankar Koley, Eunice Mah, Richard S Bruno, Maret G Traber
Electric conductivity in plasma is the balance between oxidized and reduced molecules (static Oxidation-Reduction Potential, sORP) and the amount of readily oxidizable molecules (capacity ORP, cORP). Adults with metabolic syndrome (MetS) have increased inflammation, dyslipidemia and oxidative stress; therefore, participants with MetS were hypothesized to have higher plasma sORP and lower cORP than those measures in healthy adults. Heparin-anticoagulated plasma from healthy and age- and gender-matched individuals with MetS (BMI: 22...
February 14, 2017: Redox Biology
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