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https://www.readbyqxmd.com/read/28821140/the-potential-of-cashew-gum-functionalization-as-building-blocks-for-layer-by-layer-films
#1
Álvaro J Leite, Rui R Costa, Ana M S Costa, Jeanny S Maciel, José F G Costa, Regina C M de Paula, João F Mano
Cashew gum (CG), an exudate polysaccharide from Anacardium occidentale trees, was carboxymethylated (CGCm) and oxidized (CGO). These derivatives were characterized by FTIR and zeta potential measurements confirming the success of carboxymethylation and oxidation reactions. Nanostructured multilayered films were then produced through layer-by-layer (LbL) assembly in conjugation with chitosan via electrostatic interactions or Schiff bases covalent bonds. The films were analyzed by QCM-D and AFM. CG functionalization increased the film thickness, with the highest thickness being achieved for the lowest oxidation degree...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28816836/reversal-of-dropped-head-syndrome-after-the-cessation-of-dopaminergic-agonist-treatment-in-parkinson-disease
#2
Tomoo Mano
Dropped head (DH) syndrome is a phenomenon of disproportionate neck anteflexion that has been reported in patients with Parkinson disease (PD). Antiparkinsonian medications such as dopaminergic agonists (DAs) have been implicated in the onset of DH episodes. Deep brain stimulation (DBS) is an important therapeutic option after the failure of conventional treatments such as DA therapy in patients with PD. Here, we report the case of a patient with rigid-akinetic parkinsonism who developed DH syndrome after the initiation of DA treatment...
August 14, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28812043/swallowing-markers-in-spinal-and-bulbar-muscular-atrophy
#3
Haruhiko Banno, Masahisa Katsuno, Keisuke Suzuki, Seiya Tanaka, Noriaki Suga, Atsushi Hashizume, Tomoo Mano, Amane Araki, Hirohisa Watanabe, Yasushi Fujimoto, Masahiko Yamamoto, Gen Sobue
OBJECTIVE: We examined the characteristics of dysphagia in spinal and bulbar muscular atrophy, a hereditary neuromuscular disease causing weakness of limb, facial, and oropharyngeal muscles via a videofluoroscopic swallowing study, and investigated the plausibility of using these outcome measures for quantitative analysis. METHODS: A videofluoroscopic swallowing study was performed on 111 consecutive patients with genetically confirmed spinal and bulbar muscular atrophy and 53 age- and sex-matched healthy controls...
August 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28798289/prolonged-administration-of-twice-daily-bolus-intravenous-tacrolimus-in-the-early-phase-after-lung-transplantation
#4
Yutaka Hirano, Seiichiro Sugimoto, Toshifumi Mano, Takeshi Kurosaki, Kentaroh Miyoshi, Shinji Otani, Masaomi Yamane, Motomu Kobayashi, Shinichiro Miyoshi, Takahiro Oto
BACKGROUND Although administration of tacrolimus, whether by the enteric, sublingual, or continuous intravenous routes, has some limitations, twice-daily bolus intravenous tacrolimus administration has been shown to be beneficial in optimizing efficacy and safety after lung transplantation. However, at present, the duration of bolus intravenous tacrolimus administration is limited, and the effects of prolonged bolus intravenous tacrolimus administration remain unknown. Our study was aimed at assessing the safety and efficacy of prolonged twice-daily bolus intravenous tacrolimus administration in the early phase after lung transplantation...
August 11, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28795516/the-potential-of-liquid-marbles-for-biomedical-applications-a-critical-review
#5
REVIEW
Nuno M Oliveira, Rui L Reis, João F Mano
Liquid marbles (LM) are freestanding droplets covered by micro/nanoparticles with hydrophobic/hydrophilic properties, which can be manipulated as a soft solid. The phenomenon that generates these soft structures is regarded as a different method to generate a superhydrophobic behavior in the liquid/solid interface without modifying the surface. Several applications for the LM have been reported in very different fields, however the developments for biomedical applications are very recent. At first, the LM properties are reviewed, namely shell structure, LM shape, evaporation, floatability and robustness...
August 10, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28794185/id-genes-are-essential-for-early-heart-formation
#6
Thomas J Cunningham, Michael S Yu, Wesley L McKeithan, Sean Spiering, Florent Carrette, Chun-Teng Huang, Paul J Bushway, Matthew Tierney, Sonia Albini, Mauro Giacca, Miguel Mano, Pier Lorenzo Puri, Alessandra Sacco, Pilar Ruiz-Lozano, Jean-Francois Riou, Muriel Umbhauer, Gregg Duester, Mark Mercola, Alexandre R Colas
Deciphering the fundamental mechanisms controlling cardiac specification is critical for our understanding of how heart formation is initiated during embryonic development and for applying stem cell biology to regenerative medicine and disease modeling. Using systematic and unbiased functional screening approaches, we discovered that the Id family of helix-loop-helix proteins is both necessary and sufficient to direct cardiac mesoderm formation in frog embryos and human embryonic stem cells. Mechanistically, Id proteins specify cardiac cell fate by repressing two inhibitors of cardiogenic mesoderm formation-Tcf3 and Foxa2-and activating inducers Evx1, Grrp1, and Mesp1...
August 9, 2017: Genes & Development
https://www.readbyqxmd.com/read/28794002/klf4-regulation-of-ch25h-and-lxr-mitigates-atherosclerosis-susceptibility
#7
Zhao Li, Marcy Martin, Jin Zhang, Hsi-Yuan Huang, Liang Bai, Jiao Zhang, Jian Kang, Ming He, Jie Li, Mano R Maurya, Shakti Gupta, Guangjin Zhou, Panjamaporn Sangwung, Yong-Jiang Xu, Ting Lei, Hsien-Da Huang, Mohit Jain, Mukesh K Jain, Shankar Subramaniam, John Y-J Shyy
Background -Atherosclerosis is a multifaceted inflammatory disease involving cells in the vascular wall [e.g., endothelial cells (ECs)] as well as circulating and resident immunogenic cells (e.g., monocytes/macrophages). Acting as a ligand for liver X receptor (LXR), but an inhibitor of sterol regulatory element binding protein 2 (SREBP2), 25-hydroxycholesterol (25-HC) and its catalyzing enzyme cholesterol-25-hydroxylase (Ch25h) are important in regulating cellular inflammatory status and cholesterol biosynthesis in both ECs and monocytes/macrophages...
August 9, 2017: Circulation
https://www.readbyqxmd.com/read/28792682/biomimetic-interfaces-in-biomedical-devices
#8
EDITORIAL
João F Mano, Insung S Choi, Ali Khademhosseini
No abstract text is available yet for this article.
August 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28791526/water-quality-comparison-of-secondary-effluent-and-reclaimed-water-to-ambient-river-water-of-southern-okinawa-island-via-biological-evaluation
#9
Hiroyuki Mano, Fumihiko Takeda, Tomokazu Kitamura, Seiichiro Okamoto, Yutaka Suzuki, Chang-Beom Park, Nobuhito Yasui, Kentarou Kobayashi, Yuji Tanaka, Naoyuki Yamashita, Mizuhiko Minamiyama
The objective of this work was to evaluate the biological effect of the secondary effluent (SE) of a wastewater treatment plant and reclaimed water treated via ultrafiltration (UF) followed by either reverse osmosis (RO) membrane filtration or nanofiltration (NF) to be used for environmental use by comparing the results of algal growth inhibition tests of concentrated samples of the SE and permeates of RO and NF with those of six rivers in southern Okinawa Island. Although the SE water had no adverse effects on the growth of the algae Pseudokirchneriella subcapitata, it could lead to water quality degradation of rivers in terms of its toxic unit value, whereas the use of RO and NF permeates would not lead to such degradation...
August 8, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28781179/injuries-and-illnesses-occurring-on-a-recreational-bicycle-tour-the-great-ohio-bicycle-adventure
#10
Thomas L Pommering, Diane C Manos, Bhavna Singichetti, Chelsea R Brown, Jingzhen Yang
OBJECTIVE: Recreational multiday cycling events have grown popular in the United States; however, little has been published regarding the injuries and illnesses that occur during these events. The objective of this study was to describe injuries and illnesses that occur in the Great Ohio Bicycle Adventure (GOBA) and to examine associated risk factors. METHODS: Injury and illness data collected from an on-site medical clinic during the 2013 and 2014 GOBA tours were merged with rider registration data for analysis...
August 3, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28777343/detection-of-four-distinct-volatile-indicators-of-colorectal-cancer-using-functionalized-titania-nanotubular-arrays
#11
Dhiman Bhattacharyya, Pankaj Kumar, Swomitra K Mohanty, York R Smith, Mano Misra
Screening of colorectal cancer is crucial for early stage diagnosis and treatment. Detection of volatile organic compounds (VOCs) of the metabolome present in exhaled breath is a promising approach to screen colorectal cancer (CRC). Various forms of volatile organic compounds (VOCs) that show the definitive signature for the different diseases including cancers are present in exhale breathe. Among all the reported CRC VOCs, cyclohexane, methylcyclohexane, 1,3-dimethyl- benzene and decanal are identified as the prominent ones that can be used as the signature for CRC screening...
August 4, 2017: Sensors
https://www.readbyqxmd.com/read/28770414/oral-status-quality-of-life-and-anxiety-and-depression-in-hemodialysis-patients-and-the-effect-of-the-duration-of-treatment-by-dialysis-on-these-variables
#12
F Camacho-Alonso, C Cánovas-García, C Martínez-Ortiz, T De la Mano-Espinosa, T Ortuño-Celdrán, J I Marcello-Godino, R Ramos-Sánchez, M Sánchez-Siles
This study aimed is to evaluate the oral health status, quality of life, anxiety and depression among hemodialysis patients and to analyze the effect of the duration of dialysis on these variables. 120 patients on hemodialysis and 120 control subjects underwent oral examination, periodontal evaluation, xerostomia study using a Visual Analogue Scale (VAS), sialometry evaluation; quality of life (QOL) using the OHIP-14 questionnaire and anxiety/depression. Bleeding index, CPTIN, clinical attachment level, and probing depth were significantly higher in the hemodialysis group than the control group (p < 0...
August 2, 2017: Odontology
https://www.readbyqxmd.com/read/28761251/the-effect-of-a-dentin-desensitizer-on-the-shear-bond-strength-of-composite-to-dentin-using-three-different-bonding-agents-an-in-vitro-study
#13
Eeshan Arub Mushtaq, Vijay Mathai, Rajesh Sasidharan Nair, JeyaBalaji Mano Christaine Angelo
OBJECTIVE: The effect of dentin desensitizer Systemp on the shear bond strength of composite resin to dentin using three different bonding agents, i.e., Prime & Bond NT, Xeno V(+), and Futurabond DC were evaluated. MATERIALS AND METHODS: Sixty recently extracted human premolars were divided into six groups of ten teeth each. The superficial dentin was etched with 37% phosphoric acid. In Groups I, II, and III, Prime & Bond NT, Xeno V(+), and Futurabond DC, respectively, were applied to dentin and composite placed...
January 2017: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/28755888/what-are-the-long-term-results-8-years-after-sleeve-gastrectomy
#14
Patrick Noel, Marius Nedelcu, Imane Eddbali, Thierry Manos, Michel Gagner
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) became the most frequent bariatric procedure performed in France (2011) and in the United States (2013), but studies reporting long-term results are still rare. SETTING: Private hospital, France. METHODS: This is a retrospective analysis of a prospective cohort of 168 patients who underwent LSG between 2005 and 2008. The objective of this study was to present the 8-year outcome concerning weight loss, modification of co-morbidities, and to report the revisional surgery after sleeve...
July 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28754271/afferent-cardiac-signals-modulate-attentional-engagement-to-low-spatial-frequency-fearful-faces
#15
Ruben T Azevedo, Deborah Badoud, Manos Tsakiris
Despite the growing consensus that the continuous dynamic cortical representations of internal bodily states shape the subjective experience of emotions, physiological arousal is typically considered only a consequence and rarely a determinant of the emotional experience. Recent experimental approaches study how afferent autonomic signals from the heart modulate the processing of sensory information by focussing on the phasic properties of arterial baroreceptor firing that is active during cardiac systole and quiescent during cardiac diastole...
July 4, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28751795/gender-moderates-association-between-emotional-behavioral-problems-and-text-comprehension-in-children-with-both-reading-difficulties-and-adhd
#16
Quintino R Mano, Kristen E Jastrowski Mano, Carolyn A Denton, Jeffery N Epstein, Leanne Tamm
Evidence suggests that higher order linguistic functioning such as text comprehension is particularly vulnerable to emotional modulation. Gender has been identified as an important moderating variable in emotional expression such that girls tend toward internalizing emotions (e.g., sadness, anxiety) whereas boys tend toward externalizing emotions (e.g., anger, combativeness), which may influence the relationship between emotion and text comprehension. The present study examined whether gender moderates the relationship between emotional-behavioral problems and text comprehension among children (n = 187; boys= 115, girls = 72) with both word reading difficulties (RD) and attention-deficit/hyperactivity disorder (ADHD), a sample widely acknowledged to be at increased risk for developing emotional-behavioral problems such as anxiety, poor academic self-concept, and delinquency...
May 2017: Psychology in the Schools
https://www.readbyqxmd.com/read/28727934/phylogenomics-reveals-a-complex-evolutionary-history-of-lobed-leaf-white-oaks-in-western-north-america
#17
John D McVay, Duncan Hauser, Andrew L Hipp, Paul Manos
Quercus (oak) species hybridize in complex patterns that have yet to be fully explored with phylogenomic data. Analyses to date have recovered reasonable divergent patterns, suggesting that the impact of introgression may not always be obvious in inferred oak phylogenies. We explore this phenomenon using RADseq data for 136 samples representing 54 oak species by conducting phylogenetic analyses designed to distinguish signals of lineage diversification and hybridization, focusing on the lobed-leaf species Quercus gambelii, Q...
July 20, 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28718362/adaptive-behaviour-and-motor-skills-in-children-with-upper-limb-deficiency
#18
Hiroshi Mano, Sayaka Fujiwara, Nobuhiko Haga
BACKGROUND: The dysfunction of individuals with upper limb deficiencies affects their daily lives and social participation. OBJECTIVES: To clarify the adaptive behaviours and motor skills of children with upper limb deficiencies. STUDY DESIGN: Cross-sectional survey. METHODS: The subjects were 10 children ranging from 1 to 6 years of age with unilateral upper limb deficiencies at the level distal to the elbow who were using only cosmetic or passive prostheses or none at all...
July 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/28712661/managing-incidentalomas-safely-do-computed-tomography-requisitions-tell-us-what-we-need-to-know
#19
Matthew Walker, Joy Borgaonkar, Daria Manos
PURPOSE: Technological advancements and the ever-increasing use of computed tomography (CT) have greatly increased the detection of incidental findings, including tiny pulmonary nodules. The management of many "incidentalomas" is significantly influenced by a patient's history of cancer. The study aim is to determine if CT requisitions include prior history of malignancy. METHODS: Requisitions for chest CTs performed at our adult tertiary care hospital during April 2012 were compared to a cancer history questionnaire, administered to patients at the time of CT scan...
July 13, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28705423/carbon-nanotube-fiber-mats-for-microbial-fuel-cell-electrodes
#20
Brigitte Delord, Wilfrid Neri, Karen Bertaux, Alain Derre, Isabelle Ly, Nicolas Mano, Philippe Poulin
Novel carbon nanotube based electrodes of microbial fuel cells (MFC) have been developed. MFC is a promising technology for the wastewater treatment and the production of electrical energy from redox reactions of natural substrates. Performances of such bio-electrochemical systems depend critically on the structure and properties of the electrodes. The presently developed materials are made by weaving fibers solely comprised of carbon nanotubes. They exhibit a large scale porosity controlled by the weaving process...
July 1, 2017: Bioresource Technology
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