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https://www.readbyqxmd.com/read/28324997/assessing-the-development-of-fetal-myocardial-function-by-a-novel-doppler-myocardial-performance-index
#1
Ahsan H Khandoker, F Marzbanrad, Y Kimura, Saeed Al Nuaimi, M Palaniswami
Doppler-derived myocardial performance index are used to assess aspects of systolic and diastolic function in adult as well as fetal heart. The Tei Index (TI) is a useful and non-invasive tool. The aim of this study was to determine normal values of fetal left ventricular (LV) TI in early (16-32 weeks) and late trimester (35-41 weeks) fetuses and to develop a new myocardial performance index (K-index; KI) which focuses on fetal diastolic interval when oxygenated blood from the placenta filled in the LV. Simultaneous recordings of Doppler Ultrasound Signal (DUS) of the LV outflow tracts and fetal electrocardiogram signals were obtained in 55 early- and late-trimester fetuses...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28317128/comparison-of-dce-mri-kinetic-parameters-and-fmiso-pet-uptake-parameters-in-head-and-neck-cancer-patients
#2
Urban Simoncic, Sara Leibfarth, Stefan Welz, Nina Schwenzer, Holger Schmidt, Gerald Reischl, Christina Pfannenberg, Christian la Fougère, Konstantin Nikolaou, Daniel Zips, Daniela Thorwarth
PURPOSE: Tumour hypoxia is a major cause of radiation resistance, often present in various solid tumours. Dynamic [(18) F]-fluoromisonidazole (FMISO) PET imaging is able to reliably assess tumour hypoxia. Comprehensive characterization of tumour microenvironment through FMISO-PET and dynamic contrast enhanced (DCE) MR multimodality imaging might be a valuable alternative to the dynamic FMISO-PET acquisition. The aim of this work was to explore the correlation between the FMISO-PET and DCE-MRI kinetic parameters...
March 20, 2017: Medical Physics
https://www.readbyqxmd.com/read/28315203/adc-histogram-analysis-of-cervical-cancer-aids-detecting-lymphatic-metastases-a-preliminary-study
#3
Stefan Schob, Hans Jonas Meyer, Nikolaos Pazaitis, Dominik Schramm, Kristina Bremicker, Marc Exner, Anne Kathrin Höhn, Nikita Garnov, Alexey Surov
PURPOSE: Apparent diffusion coefficient (ADC) histogram analysis has been used to some extent in cervical cancer (CC) to distinguish between low-grade and high-grade tumors. Although this differentiation is undoubtedly helpful, it would be even more crucial in the presurgical setting to determine whether a tumor already gained the potential to metastasize via the lymphatic system. So far, no studies investigated the potential of 3T ADC histogram analysis in CC to differentiate between nodal-positive and nodal-negative entities...
March 17, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28301221/diagnosis-of-internal-derangement-of-the-knee-volume-isotropic-turbo-spin-echo-acquisition-mri-with-fat-suppression-versus-without-fat-suppression
#4
Ji Hyun Lee, Young Cheol Yoon, Ki Jeong Park, Joon Ho Wang
OBJECTIVE: The purpose of this study was to compare 3D volume isotropic turbo spin-echo acquisition (VISTA) MRI with and without fat suppression for use in evaluating ligaments, menisci, and cartilage. MATERIALS AND METHODS: Two radiologists retrospectively and independently reviewed 71 MRI studies. Each study consisted of 3D intermediate-weighted VISTA images with fat suppression and without fat suppression. The presence of tears of the anterior cruciate and posterior cruciate ligaments, tears of the medial and lateral menisci, and cartilaginous defects was evaluated...
March 16, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28300783/person-recognition-system-based-on-a-combination-of-body-images-from-visible-light-and-thermal-cameras
#5
Dat Tien Nguyen, Hyung Gil Hong, Ki Wan Kim, Kang Ryoung Park
The human body contains identity information that can be used for the person recognition (verification/recognition) problem. In this paper, we propose a person recognition method using the information extracted from body images. Our research is novel in the following three ways compared to previous studies. First, we use the images of human body for recognizing individuals. To overcome the limitations of previous studies on body-based person recognition that use only visible light images for recognition, we use human body images captured by two different kinds of camera, including a visible light camera and a thermal camera...
March 16, 2017: Sensors
https://www.readbyqxmd.com/read/28298390/clinical-usefulness-of-the-free-web-based-image-analysis-application-immunoratio-for-assessment-of-ki-67-labelling-index-in-breast-cancer
#6
Min-Kyung Yeo, Hee Eun Kim, Sung Hun Kim, Byung Joo Chae, Byung Joo Song, Ahwon Lee
AIMS: Ki-67 is a prognostic marker in breast cancer; however, the use of the Ki-67 labelling index (LI) in clinical practice requires a consistent and easily accessible scoring method. The present study evaluated the use of the free internet-based image analysis program ImmunoRatio to score Ki-67 LI in breast cancer in comparison with manual counting. METHODS: Ki-67 immunohistochemical detection was performed in 577 breast cancer cases, and the Ki-67 LI was determined by ImmunoRatio and manual counting...
March 15, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28297421/characteristics-of-quantitative-perfusion-parameters-on-dynamic-contrast-enhanced-mri-in-mammographically-occult-breast-cancer
#7
Jung Kyu Ryu, Sun Jung Rhee, Jeong Yoon Song, Soo Hyun Cho, Geon-Ho Jahng
The purpose of this study was to compare the characteristics of quantitative perfusion parameters obtained from dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) in patients with mammographically occult (MO) breast cancers and those with mammographically visible (MV) breast cancers. Quantitative parameters (AUC, Ktrans,kep,ve,vp, and wi) from 13 MO breast cancers and 16 MV breast cancers were mapped after the DCE-MRI data were acquired. Various prognostic factors, including axillary nodal status, estrogen receptor (ER), progesterone receptor (PR), Ki-67, p53, E-cadherin, and human epidermal growth factor receptor 2 (HER2) were obtained in each group...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296783/incidental-thyroid-nodules-on-thoracic-contrast-enhanced-computed-tomography-in-clinical-practice-during-a-10-year-period-characteristics-clinical-outcomes-and-factors-contributing-to-further-evaluation
#8
Ju Yong Park, Kyung Hee Lee, Soon Gu Cho, Yeo Ju Kim, Ha Young Lee, In Ki Hong, Jun Ho Kim
The purposes of this study were to assess the prevalence, malignancy rate, and characteristics of incidental thyroid nodules (ITNs), and to identify factors that contribute the additional workup by ultrasound.The medical records and imaging features of ITNs reported via thoracic computed tomography (CT) were retrospectively reviewed to determine the size, multiplicity, attenuation, shape, and presence of calcification. To identify the factors associated with additional workup, we compared the workup and non-workup groups in terms of nodule characteristics, indications, and CT slices...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28295854/diffusion-kurtosis-imaging-for-differentiating-borderline-from-malignant-epithelial-ovarian-tumors-a-correlation-with-ki-67-expression
#9
Hai Ming Li, Shu Hui Zhao, Jin Wei Qiang, Guo Fu Zhang, Feng Feng, Feng Hua Ma, Yong Ai Li, Wei Yong Gu
PURPOSE: To investigate the use of diffusion kurtosis imaging (DKI) in differentiating borderline from malignant epithelial ovarian tumors (MEOTs) and to correlate DKI parameters with Ki-67 expression. MATERIALS AND METHODS: Fifty-two consecutive patients with epithelial ovarian tumors (17 borderline epithelial ovarian tumors, BEOTs; 35 MEOTs) were prospectively evaluated using DKI with b values of 0, 500, 1000, 1500, 2000, and 2500 s/mm(2) and standard diffusion-weighted imaging (DWI) with b values of 0 and 1000 s/mm(2) using a 1...
March 10, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28292297/subclinical-left-ventricular-diastolic-dysfunction-and-incident-type-2-diabetes-risk-the-korean-genome-and-epidemiology-study
#10
Juri Park, Jin-Seok Kim, Seong Hwan Kim, Sunwon Kim, Sang Yup Lim, Hong-Euy Lim, Goo-Yeong Cho, Ki-Chul Sung, Jang-Young Kim, Inkyung Baik, Kwang Kon Koh, Jung Bok Lee, Seung Ku Lee, Chol Shin
BACKGROUND: Subclinical left ventricular (LV) diastolic dysfunction in type 2 diabetes (T2D) is a common finding and represents an early sign of diabetic cardiomyopathy. However, the relationship between LV diastolic dysfunction and the incident T2D has not been previously studied. METHODS: A total of 1817 non-diabetic participants (mean age, 54 years; 48% men) from the Korean Genome and Epidemiology Study who were free of cardiovascular disease were studied. LV structure and function were assessed by conventional echocardiography and tissue Doppler imaging...
March 14, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28291421/modification-of-surgical-procedure-for-probable-limited-dorsal-myeloschisis
#11
Ji Yeoun Lee, Sangjoon Chong, Young Hun Choi, Ji Hoon Phi, Jung-Eun Cheon, Seung-Ki Kim, Sung Hye Park, In-One Kim, Kyu-Chang Wang
OBJECTIVE Since the entity limited dorsal myeloschisis (LDM) was proposed, numerous confusing clinical cases have been renamed according to the embryopathogenesis. However, clinical application of this label appears to require some clarification with regard to pathology. There have been cases in which all criteria for the diagnosis of LDM were met except for the presence of a neural component in the stalk, an entity the authors call "probable" LDM. The present study was performed to meticulously review these cases and suggest that a modified surgical strategy using limited laminectomy is sufficient to achieve the surgical goal of untethering...
February 17, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28291403/a-rat-model-of-chronic-syringomyelia-induced-by-epidural-compression-of-the-lumbar-spinal-cord
#12
Ji Yeoun Lee, Shin Won Kim, Saet Pyoul Kim, Hyeonjin Kim, Jung-Eun Cheon, Seung-Ki Kim, Sun Ha Paek, Dachling Pang, Kyu-Chang Wang
OBJECTIVE There has been no established animal model of syringomyelia associated with lumbosacral spinal lipoma. The research on the pathophysiology of syringomyelia has been focused on Chiari malformation, trauma, and inflammation. To understand the pathophysiology of syringomyelia associated with occult spinal dysraphism, a novel animal model of syringomyelia induced by chronic mechanical compression of the lumbar spinal cord was created. METHODS The model was made by epidural injection of highly concentrated paste-like kaolin solution through windows created by partial laminectomy of L-1 and L-5 vertebrae...
February 17, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28289938/primary-and-metastatic-ovarian-cancer-characterization-by-3-0t-diffusion-weighted-mri
#13
Auni Lindgren, Maarit Anttila, Suvi Rautiainen, Otso Arponen, Annukka Kivelä, Petri Mäkinen, Kirsi Härmä, Kirsi Hämäläinen, Veli-Matti Kosma, Seppo Ylä-Herttuala, Ritva Vanninen, Hanna Sallinen
OBJECTIVES: We aimed to investigate whether apparent diffusion coefficients (ADCs) measured by 3.0T diffusion-weighted magnetic resonance imaging (DWI) associate with histological aggressiveness of ovarian cancer (OC) or predict the clinical outcome. This prospective study enrolled 40 patients with primary OC, treated 2011-2014. METHODS: DWI was performed prior to surgery. Two observers used whole lesion single plane region of interest (WLsp-ROI) and five small ROIs (S-ROI) to analyze ADCs...
March 13, 2017: European Radiology
https://www.readbyqxmd.com/read/28286687/lipomatous-extensively-vacuolated-ependymoma-with-signet-ring-cell-like-appearance-analysis-of-a-case-with-extensive-literature-review
#14
Miguel Fdo Salazar, Martha Lilia Tena-Suck, Alma Ortiz-Plata, Citlaltepetl Salinas-Lara, Daniel Rembao-Bojórquez
"Lipomatous" and "extensively vacuolated" are descriptive captions that have been used to portray a curious subset of ependymomas distinctively bearing cells with a large vacuole pushing the nucleus to the periphery and, thus, simulating a signet-ring cell appearance. Here, we would like to report the first ependymoma of this kind in a Latin American institution. A 16-year-old boy experienced cephalea during three months. Magnetic resonance imaging scans showed a left paraventricular tumour which corresponded to anaplastic ependymoma...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28283025/ganglion-cell-inner-plexiform-layer-and-retinal-nerve-fiber-layer-thickness-according-to-myopia-and-optic-disc-area-a-quantitative-and-three-dimensional-analysis
#15
Sam Seo, Chong Eun Lee, Jae Hoon Jeong, Ki Ho Park, Dong Myung Kim, Jin Wook Jeoung
BACKGROUND: To determine the influences of myopia and optic disc size on ganglion cell-inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (RNFL) thickness profiles obtained by spectral domain optical coherence tomography (OCT). METHODS: One hundred and sixty-eight eyes of 168 young myopic subjects were recruited and assigned to one of three groups according to their spherical equivalent (SE) values and optic disc area. All underwent Cirrus HD-OCT imaging...
March 11, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28278561/the-role-of-surgical-clips-in-the-evaluation-of-interfractional-uncertainty-for-treatment-of-hepatobiliary-and-pancreatic-cancer-with-postoperative-radiotherapy
#16
Jin Suk Bae, Dong Hyun Kim, Won Taek Kim, Yong Ho Kim, Dahl Park, Yong Kan Ki
Purpose: To evaluate the utility of implanted surgical clips for detecting interfractional errors in the treatment of hepatobiliary and pancreatic cancer with postoperative radiotherapy (PORT). Methods and Materials: Twenty patients had been treated with PORT for locally advanced hepatobiliary or pancreatic cancer, from November 2014 to April 2016. Patients underwent computed tomography simulation and were treated in expiratory breathing phase. During treatment, orthogonal kilovoltage (kV) imaging was taken twice a week, and isocenter shifts were made to match bony anatomy...
March 10, 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28278560/hepatogastric-fistula-as-a-rare-complication-of-pyogenic-liver-abscess
#17
Kyu Won Lee, Hee Yeon Kim, Chang Wook Kim, Young Ki Kim, Ohbeom Kwon, Min Ah Kim, Youngyun Cho, Keungmo Yang
Hepatogastric fistula following a pyogenic liver abscess is extremely rare, and only a handful of cases have been reported. An 88-year-old female presented with generalized weakness, fever and chills. An abdominal computed tomography scan revealed a 5cm-sized hypodense lesion with internal septa in the left lateral section of the liver. Due to initial suspicion of early liver abscess, she was treated with empirical intravenous antibiotics. Initially, aspiration or drainage of the liver abscess was not performed due to immature lesion characteristics...
March 9, 2017: Clinical and Molecular Hepatology
https://www.readbyqxmd.com/read/28276477/in-vivo-longitudinal-visualization-of-bone-marrow-engraftment-process-in-mouse-calvaria-using-two-photon-microscopy
#18
Viet-Hoan Le, Seunghun Lee, Seungwon Lee, Taejun Wang, Won Hyuk Jang, Yeoreum Yoon, Soonjae Kwon, Hyekang Kim, Seung-Woo Lee, Ki Hean Kim
Intravital microscopy of mouse calvarial bone marrow (BM) is a powerful method for studying hematopoietic stem cells (HSCs) and the BM microenvironment at the cellular level. However, the current method used to access the mouse calvaria allows for only a few imaging times in the same mouse because of scar formation and inflammation induced by multiple surgeries. Longitudinal imaging of the BM may help better understand its microenvironment. In this study, a mouse calvarial window model was developed for longitudinal imaging that involves attaching a cover glass window onto the mouse calvaria and sealing the surrounding exposed area with cyanoacrylate glue and dental cement...
March 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28271650/usefulness-of-blood-cultures-and-radiologic-imaging-studies-in-the-management-of-patients-with-community-acquired-acute-pyelonephritis
#19
Yeonjae Kim, Mi Ran Seo, Seong Jong Kim, Jieun Kim, Seong Heon Wie, Yong Kyun Cho, Seung Kwan Lim, Jin Seo Lee, Ki Tae Kwon, Hyuck Lee, Hee Jin Cheong, Dae Won Park, Seong Yeol Ryu, Moon Hyun Chung, Hyunjoo Pai
BACKGROUND: The objective of this study was to examine the usefulness of blood cultures and radiologic imaging studies for developing therapeutic strategies in community-acquired acute pyelonephritis (CA-APN) patients. MATERIALS AND METHODS: We prospectively collected the clinical data of CA-APN patients who visited 11 hospitals from March 2010 to February 2011. RESULTS: Positive urine and blood cultures were obtained in 69.3% (568/820) and 42...
February 24, 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/28270983/clinically-compatible-flexible-wide-field-multi-color-fluorescence-endoscopy-with-a-porcine-colon-model
#20
Gyugnseok Oh, Youngrong Park, Su Woong Yoo, Soonjoo Hwang, Alexey V Dan Chin-Yu, Yeon-Mi Ryu, Sang-Yeob Kim, Eun-Ju Do, Ki Hean Kim, Sungjee Kim, Seung-Jae Myung, Euiheon Chung
Early detection of structural or molecular changes in dysplastic epithelial tissues is crucial for cancer screening and surveillance. Multi-targeting molecular endoscopic fluorescence imaging may improve noninvasive detection of precancerous lesions in the colon. Here, we report the first clinically compatible, wide-field-of-view, multi-color fluorescence endoscopy with a leached fiber bundle scope using a porcine model. A porcine colon model that resembles the human colon is used for the detection of surrogate tumors composed of multiple biocompatible fluorophores (FITC, ICG, and heavy metal-free quantum dots (hfQDs))...
February 1, 2017: Biomedical Optics Express
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