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https://www.readbyqxmd.com/read/28231689/are-children-with-asthma-in-south-korea-also-associated-with-vitamin-d-deficiency
#1
Yu-Ri Kim, Sung-Chul Seo, Young Yoo, Ji Tae Choung
Recently, epidemiologic studies have shown that the lack of vitamin D levels may be associated with high asthma prevalence, but its effect is still controversial, depending on season, area, and food consumption. We aimed to examine the association of serum vitamin D levels with the prevalence of pediatric asthma in Korea. A total of 80 children (50 asthmatic children and 30 healthy controls) aged 6-14 years were participated in this study. Serum 25-hydroxy vitamin D (vitamin D) levels were measured and compared between the two groups...
February 14, 2017: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28231682/unmet-needs-of-the-patients-with-obsessive-compulsive-disorder
#2
(no author information available yet)
BACKGROUND: Obsessive compulsive disorder (OCD) is a disabling mental disorder with the chronic and difficult course. The disorder is accompanied by numerous limitations in personal and interpersonal functioning. OCD decreases the quality of life and the chance to maintain relationships and professional status. The patients with OCD often experience a severe disabling course of the disorder. Even the individuals, who follow treatment advice, are often still highly symptomatic. In the last decade, the concept of the needs has been assessed as an extent of the traditional outcome evaluation in order to focus on the identification of the specific needs of the patients and their relatives, improve the patients´ overall mental condition and quality of life, and also to increase the treatment effectiveness of the mental disorders...
October 24, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28231675/-effect-of-gender-on-the-prognosis-of-patients-with-non-small-cell-lung-cancer
#3
Q P Xu, F He, Z Q Liu, W M Xiong, J B Lin, L Cai
Objective: To analyze the effect of gender on the prognosis of patients with non-small cell lung cancer (NSCLC). Methods: Data of 1 195 patients with NSCLC were analyzed by Chi-square, Kaplan-Meier, log-rank tests and Cox regression models. Results: Women had a longer survival than men (median overall survival 31.64 versus 22.71 months, P<0.01) in the participants of this study. Differences seen in overall survival remained the similar, after stratified by age, pathologic types, clinical stage, sizes, pleural effusion and surgery of the patients, respectively...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231674/-a-preliminary-study-on-the-molecular-characteristics-of-d-cycloserine-resistance-of-mycobacterium-tuberculosis
#4
C Li, G L Li, Q Luo, S J Li, R B Wang, Y L Lou, J X Lyu, K L Wan
Objective: To investigate the relationship between D-cycloserine resistance and the gene mutations of alrA, ddlA and cycA of Mycobacterium (M.) tuberculosis, as well as the association between D-cycloserine resistance and spoligotyping genotyping. Methods: A total of 145 M. tuberculosis strains were selected from the strain bank. D-cycloserine resistant phenotypes of the strains were determined by the proportion method and the minimal inhibitory concentration was determined by resazurin microtiter assay. PCR amplification and DNA direct sequencing methods were used for the analysis of gene mutations...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231658/-relationship-between-reproductive-history-and-preterm-births-in-the-last-pregnancy-in-shaanxi-province
#5
B W Qin, J Ying, Q Lei, P F Qu, F L Lei, J M Li, H Yan
Objective: To analyze the incidence of preterm delivery among single live neonates and the association between maternal reproductive history and preterm birth. Methods: A questionnaire survey was conducted on reproductive history among women at childbearing age who were selected through multi-stage stratified random sampling method in Shaanxi, during 2010-2013. Samples would include women at childbearing age and in pregnancy or having had definite pregnancy outcomes. Results: A total of 29 608 women at childbearing age with their infants, were studied...
February 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28231649/optimal-timing-for-hemoglobin-concentration-determination-after-total-knee-arthroplasty-day-1-versus-day-2
#6
Mahdi Yacine Khalfaoui, Charles Godavitarne, Michael C P Wilkinson
Purpose: Postoperative hemoglobin (Hb) determination remains an essential parameter for quantifying blood loss following total knee replacement (TKR) surgery and guiding transfusion practice. In this study we aimed to ascertain the optimal timing for Hb determination postoperatively and assess its relationship to serum hematocrit (Hct). Materials and Methods: This was a retrospective cohort analysis of 61 consecutive patients undergoing preoperative, day 1 and day 2 Hb and Hct concentration determination following TKR surgery...
March 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28231615/what-do-older-people-experiencing-loneliness-think-about-primary-care-or-community-based-interventions-to-reduce-loneliness-a-qualitative-study-in-england
#7
Kalpa Kharicha, Steve Iliffe, Jill Manthorpe, Carolyn A Chew-Graham, Mima Cattan, Claire Goodman, Maggie Kirby-Barr, Janet H Whitehouse, Kate Walters
Loneliness in later life is a common problem with poor health outcomes. However, interventions to prevent or ameliorate loneliness have a weak evidence base. The views of older people experiencing or at risk of loneliness in the community are important in identifying features of potential support, but have been little studied. Twenty-eight community dwelling people, aged 65 and over who reported being 'lonely much of the time' or identified as lonely from the de Jong Gierveld six-item loneliness scale in a larger study, participated in in-depth interviews, between June 2013 and May 2014...
February 23, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28231613/genetic-determinism-vs-phenotypic-plasticity-in-protist-morphology
#8
Matthieu Mulot, Katarzyna Marcisz, Lara Grandgirard, Enrique Lara, Anush Kosakyan, Bjorn J M Robroek, Mariusz Lamentowicz, Richard J Payne, Edward A D Mitchell
Untangling the relationships between morphology and phylogeny is key to building a reliable taxonomy, but is especially challenging for protists, where the existence of cryptic or pseudocryptic species makes finding relevant discriminant traits difficult. Here we use Hyalosphenia papilio (a testate amoeba) as a model species to investigate the contribution of phylogeny and phenotypic plasticity in its morphology. We study the response of Hyalosphenia papilio morphology (shape and pores number) to environmental variables in 1) a manipulative experiment with controlled conditions (water level), 2) an observational study of a withinsite natural ecological gradient (water level), and 3) an observational study across 37 European peatlands (climate)...
February 23, 2017: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/28231608/quantitative-analysis-of-malondialdehyde-guanine-adducts-in-genomic-dna-samples-by-liquid-chromatography-tandem-mass-spectrometry
#9
S A Yates, N M Dempster, M F Murphy, S A Moore
RATIONALE: The lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals. METHODS: Genomic DNA samples were subjected to acid hydrolysis to release the adducts in the base form (M1 G) alongside the other purines. A liquid chromatography-mass spectrometry method was optimised for the quantitation of the M1 G adducts in genomic DNA samples using product ion and multiple reaction mode scans...
February 23, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28231604/variations-in-body-morphology-explain-gender-differences-in-thermoeffector-function-during-compensable-heat-stress
#10
Sean R Notley, Joonhee Park, Kyoko Tagami, Norikazu Ohnishi, Nigel A S Taylor
Gender is sometimes thought to independently modulate cutaneous vasomotor and sudomotor function during heat exposure. Nevertheless, it was hypothesised that, when assessed during compensable exercise that evoked equal heat-loss requirements across participants, gender differences in those thermoeffectors would be explained by variations in the ratio between body surface area and mass (specific surface area). To evaluate that possibility, vasomotor and sudomotor functions were assessed in sixty individuals (36 males, 24 females) with widely varying (overlapping) specific surface areas (range: 232...
February 23, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28231600/validation-of-the-36-item-version-of-the-who-disability-assessment-schedule-2-0-whodas-2-0-for-assessing-women-s-disability-and-functioning-associated-with-maternal-morbidity
#11
Carla Silveira, Mary Angela Parpinelli, Rodolfo Carvalho Pacagnella, Carla Betina Andreucci, Carina Robles Angelini, Elton Carlos Ferreira, José Guilherme Cecatti
Objective To validate the translation and adaptation to Brazilian Portuguese of 36 items from the World Health Organizaton Disability Assessment Schedule 2.0 (WHODAS 2.0), regarding their content and structure (construct), in a female population after pregnancy. Methods This is a validation of an instrument for the evaluation of disability and functioning and an assessment of its psychometric properties, performed in a tertiary maternity and a referral center specialized in high-risk pregnancies in Brazil...
February 23, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28231553/a-reusable-aptasensor-of-thrombin-based-on-dna-machine-employing-resonance-light-scattering-technique
#12
Yining Hou, Jifeng Liu, Min Hong, Xia Li, Yanhua Ma, Qiaoli Yue, Chen-Zhong Li
The design of molecular nanodevices attracted great interest in these years. Herein, a reusable, sensitive and specific aptasensor was constructed based on an extension-contraction movement of DNA interconversion for the application of human thrombin detection. The present biosensor was based on resonance light scattering (RLS) using magnetic nanoparticles (MNPs) as the RLS probe. MNPs coated with streptavidin can combine with biotin labeled thrombin aptamers. The combined nanoparticles composite is monodispersed in aqueous medium...
February 20, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28231551/acute-effect-of-ozone-exposure-on-daily-mortality-in-seven-cities-of-jiangsu-province-china-no-clear-evidence-for-threshold
#13
Kai Chen, Lian Zhou, Xiaodong Chen, Jun Bi, Patrick L Kinney
BACKGROUND: Few multicity studies have addressed the health effects of ozone in China due to the scarcity of ozone monitoring data. A critical scientific and policy-relevant question is whether a threshold exists in the ozone-mortality relationship. METHODS: Using a generalized additive model and a univariate random-effects meta-analysis, this research evaluated the relationship between short-term ozone exposure and daily total mortality in seven cities of Jiangsu Province, China during 2013-2014...
February 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28231550/short-term-particulate-matter-exposure-induces-extracellular-vesicle-release-in-overweight-subjects
#14
Matteo Bonzini, Laura Pergoli, Laura Cantone, Mirjam Hoxha, Andrea Spinazzè, Luca Del Buono, Chiara Favero, Michele Carugno, Laura Angelici, Lucia Broggi, Andrea Cattaneo, Angela C Pesatori, Valentina Bollati
BACKGROUND: Extracellular vesicles (EVs) represent a plausible molecular mechanism linking particulate matter (PM) inhalation to its systemic effects. Microvesicles (MVs) are released from many cell types in response to various stimuli. Increased body mass index (BMI) could modify the response to PM exposure due to enhanced PM uptake and/or an underlying pro-oxidative state. We investigated the relationship between EV release and PM10/PM2.5 exposure in a cohort of 51 volunteers. Subjects were stratified based on their BMI to evaluate whether overweight BMI is a determinant of hypersusceptibility to PM effects...
February 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28231537/release-kinetics-of-esterified-p-coumaric-acid-and-ferulic-acid-from-rice-straw-in-mild-alkaline-solution
#15
Tran Ngoc Linh, Hirokata Fujita, Akiyoshi Sakoda
The release kinetics of esterified p-coumaric acid (PCA) and ferulic acid (FA) from rice straw under a mild alkaline condition were investigated to collect fundamental data for the design of a recovery process. The results showed that the straw size, NaOH concentration, and temperature were the key parameters governing release kinetics. The analysis demonstrated that FA is released considerably faster than PCA. The close relationship between lignin and the PCA dissolution indicates a reciprocal and/or simultaneous release...
February 7, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28231525/construction-of-new-est-ssrs-for-fusarium-resistant-wheat-breeding
#16
Aysen Yumurtaci, Hulya Sipahi, Ayed Al-Abdallat, Abdulqader Jighly, Michael Baum
Surveying Fusarium resistance in wheat with easy applicable molecular markers such as simple sequence repeats (SSRs) is a prerequest for molecular breeding. Expressed sequence tags (ESTs) are one of the main sources for development of new SSR candidates. Therefore, 18.292 publicly available wheat ESTs were mined and genotyping of newly developed 55 EST-SSR derived primer pairs produced clear fragments in ten wheat cultivars carrying different levels of Fusarium resistance. Among the proved markers, 23 polymorphic EST-SSRs were obtained and related alleles were mostly found on B and D genome...
February 11, 2017: Computational Biology and Chemistry
https://www.readbyqxmd.com/read/28231521/therapeutic-journey-of-2-4-thiazolidinediones-as-a-versatile-scaffold-an-insight-into-structure-activity-relationship
#17
REVIEW
Mohd Javed Naim, Md Jahangir Alam, Shujauddin Ahmad, Farah Nawaz, Neelima Shrivastava, Meeta Sahu, Ozair Alam
Thiazolidinedione is an important heterocyclic ring system, a pharmacophore and a privileged scaffold in medicinal chemistry; is a derivative of thiazolidine ring which came into existence for its role as antihyperglycemic agent and a specific ligand of PPAR's (Peroxisome proliferator activated receptor). Exhaustive research has led to determination of its vast biological profile with wide range of therapeutic applications. This review covers recent pharmacological advancements of thiazolidinedione moiety along with structure activity relationship so as to provide better correlation among different structures and their receptor interactions...
February 20, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28231497/dienogest-and-deep-infiltrating-endometriosis-the-remission-of-symptoms-is-not-related-to-endometriosis-nodule-remission
#18
Joao Paulo Leonardo-Pinto, Cristina Laguna Benetti-Pinto, Kleber Cursino, Daniela Angerame Yela
OBJECTIVE: To evaluate the effectiveness of dienogest in controlling pain caused by deep infiltrating endometriosis (DIE), its influence on the quality of live (QoL) of women affected by the disease, and the effect of the drug on the volume of endometriotic lesions. STUDY DESIGN: A prospective cohort study including 30 women with a sonographic diagnosis of DIE (intestinal and posterior fornix) treated with dienogest 2mg per day for 12 months. We evaluated the pain symptoms and the volume of the intestinal and posterior fornix lesions before and after 12 months of use of dienogest...
February 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28231485/the-importance-of-teacher-support-differential-impacts-by-gender-and-sexuality
#19
Adrienne B Dessel, Alex Kulick, Laura J Wernick, Daniel Sullivan
Teachers play an important role in shaping the experiences of high school students with regard to patterns of heteronormativity and binary gender norms, particularly for lesbian, gay, bisexual, transgender, and questioning (LGBTQ) students. A climate survey of high school students (n = 953) in the United States examined the association between students' well-being and their relationships with teachers. The sample was majority white (65.8%) and multiracial (14.1%). Cisgender (cis)-girls (49.6%), cis-boys (41...
February 20, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28231484/exploratory-investigation-of-theoretical-predictors-of-nomophobia-using-the-mobile-phone-involvement-questionnaire-mpiq
#20
Lidia Argumosa-Villar, Joan Boada-Grau, Andreu Vigil-Colet
Despite the advantages that the development of new technologies has brought to our lives, it is also true that the problematic use of technology can have negative effects on some people, as the prevalence of nomophobia, defined as the fear and anxiety of being unreachable via one's mobile phone. While some authors are beginning to study the relationship of nomophobia with variables such as age, no investigation has yet been carried out into psychological variables. Our study contributes to the literature by looking at personality, self-esteem, gender and age as predictors of nomophobia, evaluated by the Mobile Phone Involvement Questionnaire (MPIQ)...
February 20, 2017: Journal of Adolescence
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