keyword
MENU ▼
Read by QxMD icon Read
search

"Central Sensitivity Syndrome"

keyword
https://www.readbyqxmd.com/read/28683025/visceral-pain-as-a-triggering-factor-for-fibromyalgia-symptoms-in-comorbid-patients
#1
Raffaele Costantini, Giannapia Affaitati, Ursula Wesselmann, Peter Czakanski, Maria Adele Giamberardino
Fibromyalgia syndrome (FMS) is a central sensitization syndrome; however, peripheral pain sources potentially exacerbate its symptoms of chronic diffuse musculoskeletal pain and hyperalgesia. This prospective study evaluated visceral pain as a possible triggering factor for FMS pain and hyperalgesia in comorbid patients. Women with (1) FMS + irritable bowel syndrome (IBS); (2) FMS + primary dysmenorrhea (Dys); (3) FMS + Dys secondary to endometriosis (Endo); (4) FMS + colon diverticulosis (Div) were compared with FMS-only women, for fibromyalgia pain (number and intensity of episodes and analgesic consumption) over comparable periods and for somatic hyperalgesia (electrical and pressure pain thresholds) in painful (tender points) and control areas (trapezius, deltoid, quadriceps muscles, and overlying subcutis and skin)...
July 3, 2017: Pain
https://www.readbyqxmd.com/read/28681628/the-management-of-fibromyalgia-from-a-psychosomatic-perspective-an-overview
#2
Federica Sancassiani, Sergio Machado, Valeria Ruggiero, Enrico Cacace, Claudia Carmassi, Camilla Gesi, Liliana Dell'Osso, Mauro Giovanni Carta
Fibromyalgia (FM) is a central sensitization syndrome characterized by chronic widespread pain. FM is often comorbid with psychiatric disorders, as well as psychological distress that worsens the quality-of-life of people affected. The aim was to collect current evidence about the management of FM from a psychosomatic perspective. The literature was synthesized and summarized in a narrative format. The literature search was carried out in PubMed; review articles, meta-analysis, overview, and guidelines published in the last 10 years written in English were included...
July 6, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28619687/use-of-the-central-sensitization-inventory-csi-as-a-treatment-outcome-measure-for-chronic-spinal-pain-disorder-patients-in-a-functional-restoration-program
#3
Randy Neblett, Meredith M Hartzell, Mark Williams, Kelley R Bevers, Tom G Mayer, Robert J Gatchel
BACKGROUND CONTEXT: The Central Sensitization Inventory (CSI) is a valid and reliable patient-reported instrument designed to identify patients whose presenting symptoms may be related to Central Sensitization (CS). Part A of the CSI measures a full array of 25 somatic and emotional symptoms associated with CS, and Part B asks if patients have previously been diagnosed with one or more specific Central Sensitivity Syndromes (CSSs) and related disorders. The CSI has previously been validated in a group of chronic pain patients who were screened by a trained psychiatrist for specific CSS diagnoses...
June 12, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28449376/psychological-distress-and-widespread-pain-contribute-to-the-variance-of-the-central-sensitization-inventory-a-cross-sectional-study-in-patients-with-chronic-pain
#4
C P van Wilgen, P J Vuijk, J Kregel, L Voogt, M Meeus, F Descheemaker, D Keizer, J Nijs
OBJECTIVES: Central sensitization (CS) implies increased sensitivity of the nervous system, resulting in increased pain sensitivity as well as widespread pain. Recently, the Central Sensitization Inventory (CSI) was developed to assess symptoms of CS and central sensitivity syndromes. The aim of this study was to examine the convergent validity of the CSI by comparing the outcome to psychosocial factors and clinical features of CS. METHODS: In a cross-sectional explorative study, patients with chronic pain completed multiple questionnaires, including the CSI, pain catastrophizing scale, SCL-90 for psychological distress, duration of pain, intensity of pain, widespread pain, and lateralization of pain...
April 27, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27818875/cross-cultural-adaptation-and-validity-of-the-spanish-central-sensitization-inventory
#5
Antonio Ignacio Cuesta-Vargas, Cristina Roldan-Jimenez, Randy Neblett, Robert J Gatchel
PURPOSING: The Central Sensitization Inventory (CSI) is a new patient-reported instrument, which measures symptoms related to Central Sensitivity Syndromes and Central Sensitization. The aim of this study was to translate the CSI into Spanish, and then to perform a psychometric validation, including a factor analysis to reveal the underlying structure. METHODS: In this two-stage psychometric study participated 395 subjects with various chronic pain conditions and that were recruited from two Primary Care Centres...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27471458/motor-cortex-excitability-and-bdnf-levels-in-chronic-musculoskeletal-pain-according-to-structural-pathology
#6
Wolnei Caumo, Alícia Deitos, Sandra Carvalho, Jorge Leite, Fabiana Carvalho, Jairo Alberto Dussán-Sarria, Maria da Graça Lopes Tarragó, Andressa Souza, Iraci Lucena da Silva Torres, Felipe Fregni
The central sensitization syndrome (CSS) encompasses disorders with overlapping symptoms in a structural pathology spectrum ranging from persistent nociception [e.g., osteoarthritis (OA)] to an absence of tissue injuries such as the one presented in fibromyalgia (FM) and myofascial pain syndrome (MPS). First, we hypothesized that these syndromes present differences in their cortical excitability parameters assessed by transcranial magnetic stimulation (TMS), namely motor evoked potential (MEP), cortical silent period (CSP), short intracortical inhibition (SICI) and short intracortical facilitation (SICF)...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27367486/somatic-syndromes-and-chronic-pain-in-women-with-overactive-bladder
#7
W Stuart Reynolds, Stephen Mock, Xuechao Zhang, Melissa Kaufman, Alan Wein, Stephen Bruehl, Roger Dmochowski
AIMS: Mechanisms underlying pain perception and afferent hypersensitivity, such as central sensitization, may impact overactive bladder (OAB) symptoms. However, little is known about associations between OAB symptom severity, pain experience, and presence of comorbid chronic pain syndromes. This study examined relationships between OAB symptoms, somatic symptoms, and specific chronic pain conditions in which central sensitization is believed to play a primary role, in a community-based sample of adult women with OAB...
April 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27195643/chronic-pain-without-clear-etiology-in-low-and-middle-income-countries-a-narrative-review
#8
REVIEW
Tracy Jackson, Sarah Thomas, Victoria Stabile, Xue Han, Matthew Shotwell, K A Kelly McQueen
Globally, 8 of the top 12 disabling conditions are related either to chronic pain or to the psychological conditions strongly associated with persistent pain. In this narrative review, we explore the demographic and psychosocial associations with chronic pain exclusively from low- and middle-income countries (LMICs) and compare them with current global data. One hundred nineteen publications in 28 LMICs were identified for review; associations with depression, anxiety, posttraumatic stress, insomnia, disability, gender, age, rural/urban location, education level, income, and additional sites of pain were analyzed for each type of chronic pain without clear etiology...
June 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27105483/fibromyalgia-syndrome-pathology-and-environmental-influences-on-afflictions-with-medically-unexplained-symptoms
#9
REVIEW
Phillip J Albrecht, Frank L Rice
Fibromyalgia syndrome (FMS) is a clinical disorder predominant in females with unknown etiology and medically unexplained symptoms (MUS), similar to other afflictions, including irritable bowel syndrome (IBS), chronic fatigue syndrome (CFS), post-traumatic stress disorder (PTSD), Gulf War illness (GFI), and others. External environmental stimuli drive behavior and impact physiologic homeostasis (internal environment) via autonomic functioning. These environments directly impact the individual affective state (mind), which feeds back to regulate physiology (body)...
June 1, 2016: Reviews on Environmental Health
https://www.readbyqxmd.com/read/26989894/establishing-clinically-relevant-severity-levels-for-the-central-sensitization-inventory
#10
Randy Neblett, Meredith M Hartzell, Tom G Mayer, Howard Cohen, Robert J Gatchel
OBJECTIVES: The aim of this study was to create and validate severity levels for the central sensitization inventory (CSI), a valid and reliable patient-reported outcome instrument designed to identify patients whose presenting symptoms may be related to a central sensitivity syndrome (CSS; eg, fibromyalgia, chronic fatigue syndrome, irritable bowel syndrome), with a proposed common etiology of central sensitization (CS). METHODS: Based on CSI score means and standard deviations from previously published subject samples, the following CSI severity levels were established: subclinical = 0 to 29; mild = 30 to 39; moderate = 40 to 49; severe = 50 to 59; and extreme = 60 to 100...
February 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/26602519/can-mastalgia-be-another-somatic-symptom-in-fibromyalgia-syndrome
#11
Meral Sen, Murat Ozgur Kilic, Ozlem Cemeroglu, Duygu Icen
OBJECTIVE: The purposes of this study were to determine the coexistence of mastalgia and fibromyalgia, to investigate the effects of this combination on pain patterns, and to discuss the status of breast pain in the diagnostic algorithm of fibromyalgia syndrome. METHODS: Sixty-one female patients reporting breast pain during the last three months and 53 female patients diagnosed with fibromyalgia syndrome were enrolled in this study. The Breast Pain Questionnaire was administered to all participants in the mastalgia group and to those in the fibromyalgia syndrome group who had experienced mastalgia during the past three months...
November 2015: Clinics
https://www.readbyqxmd.com/read/26549386/a-systematic-review-of-the-comorbidity-between-temporomandibular-disorders-and-chronic-fatigue-syndrome
#12
REVIEW
L J Robinson, J Durham, J L Newton
UNLABELLED: The most common cause of chronic oro-facial pain is a group of disorders collectively termed temporomandibular disorders (TMDs). Chronic painful TMD is thought to be a 'central sensitivity syndrome' related to hypersensitivity of the nervous system, but the cause is unknown. A similar understanding is proposed for other unexplained conditions, including chronic fatigue syndrome (CFS). Exploring the comorbidity of the two conditions is a valuable first step in identifying potential common aetiological mechanisms or treatment targets...
April 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/26449588/relationship-of-physical-distress-to-dizziness-in-patients-with-fibromyalgia
#13
Fusako Sawada, Yasuyuki Nomura, Fumiyuki Goto, Masato Murakami, Maki Jike, Teruo Toi, Tohru Furusaka, Minoru Ikeda, Takeshi Oshima
CONCLUSIONS: The feelings of dizziness and unsteadiness of the patients with fibromyalgia supposed specifically amplified by the hypersensitivity mechanism of CSS (central sensitivity syndrome) of them. The severity of subjective pain and physical distress according to the questionnaires were not correlated with the objective body sway on the stabilometer. OBJECTIVES: Fibromyalgia manifests primarily as chronic pain of the entire body, but is also often associated with a variety of physical symptoms including dizziness and unsteadiness...
2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/26212380/neurological-and-endocrine-phenotypes-of-fragile-x-carrier-women
#14
D Hall, K Todorova-Koteva, S Pandya, B Bernard, B Ouyang, M Walsh, T Pounardjian, C Deburghraeve, L Zhou, M Losh, M Leehey, E Berry-Kravis
Women who carry fragile X mental retardation 1 (FMR1)gene premutation expansions frequently report neurological or endocrine symptoms and prior studies have predominantly focused on questionnaire report of medical issues. Premutation carrier (PMC) women (n = 33) and non-carrier controls (n = 13) were recruited and evaluated by a neurologist, neuropsychologist, and endocrinologist. Blood and skin biopsies were collected for molecular measures. Scales for movement disorders, neuropathy, cognitive function, psychiatric symptoms, sleep, and quality of life were completed...
January 2016: Clinical Genetics
https://www.readbyqxmd.com/read/26138918/editorial-review-an-update-on-central-sensitivity-syndromes-and-the-issues-of-nosology-and-psychobiology
#15
REVIEW
Muhammad B Yunus
Central sensitization (CS), simply defined as an amplified response of the central nervous system to peripheral input, is a concept of great importance in clinical medicine. It has helped to explain aspects of the pathophysiology of common diseases, e.g. fibromyalgia syndrome (FMS), irritable bowel syndrome, vulvodynia, headaches, chronic pelvic pain and other overlapping conditions (collectively called central sensitivity syndromes, or CSS). It also applies to pain of complex regional pain syndrome, osteoarthritis (OA), rheumatoid arthritis (RA) and post-operative pain...
2015: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/26088214/cytokine-and-immune-system-abnormalities-in-fibromyalgia-and-other-central-sensitivity-syndromes
#16
REVIEW
Roland Staud
The nervous system as well as the immune system use common signaling molecules for intra- and inter-system communications. Specifically, both entities produce a similar array of peptide and non-peptide transmitters that act on a common set of receptors present in the two systems. One important set of such signaling molecules are cytokines. The wide distribution of cytokine receptors throughout the body, including the immune and the nervous system allows direct communication between these two entities. In addition to cytokines the nervous system and immune system also communicate with each other using shared ligands such as neurotransmitters and neuroendocrine hormones, and their respective receptors...
2015: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/26088213/fibromyalgia-the-prototypical-central-sensitivity-syndrome
#17
REVIEW
Chad S Boomershine
Fibromyalgia syndrome (FM), the most common central sensitivity syndrome (CSS) affecting over 5% of the population, is a disorder of chronic widespread pain accompanied by numerous other symptoms that causes significant functional impairment. The core FM symptom domains can be recalled using the FIBRO mnemonic and include Fatigue and Fog (cognitive dysfunction), Insomnia (difficulties with all aspects of sleep including initiation, maintenance and restorative), Blues (depression and anxiety), Rigidity (stiffness in muscles and joints) and Ow! (widespread pain and tenderness)...
2015: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/26088212/programmed-symptoms-disparate-effects-united-by-purpose
#18
REVIEW
Richard H Gracely, Petra Schweinhardt
Central sensitivity syndromes (CSS) share features of similar multiple symptoms, virtually unknown mechanisms and lack of effective treatments. The CSS nomenclature was chosen over alternatives because it focused on a putative physiological mechanism of central sensitization common to disorders such as fibromyalgia, irritable bowel syndrome, vulvodynia and temporomandibular disorder. Increasing evidence from multiple biological systems suggests a further development. In this new model central sensitization is part of a ensemble that includes also the symptoms of widespread pain, fatigue, unrefreshing sleep and dyscognition...
2015: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/26088211/psychosocial-factors-and-central-sensitivity-syndromes
#19
REVIEW
Leah M Adams, Dennis C Turk
Central sensitivity syndromes (CSSs) represent a heterogeneous group of disorders (e.g., fibromyalgia [FM], irritable bowel syndrome [IBS], chronic headache, temporomandibular disorders [TMDs], pelvic pain syndromes) that share many common symptoms, with persistent pain being the most prominent feature. Although the etiology and pathophysiology of CSSs are currently incompletely understood, central sensitization has emerged as one of the significant mechanisms. Given that there are currently no known cures for CSSs, people living with these disorders must learn to cope with and manage their symptoms throughout their lives...
2015: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/25973272/central-sensitization-syndrome-and-the-initial-evaluation-of-a-patient-with-fibromyalgia-a-review
#20
REVIEW
Kevin C Fleming, Mary M Volcheck
In both primary care and consultative practices, patients presenting with fibromyalgia (FM) often have other medically unexplained somatic symptoms and are ultimately diagnosed as having central sensitization (CS). Central sensitization encompasses many disorders where the central nervous system amplifies sensory input across many organ systems and results in myriad symptoms. A pragmatic approach to evaluate FM and related symptoms, including a focused review of medical records, interviewing techniques, and observations, is offered here, giving valuable tools for identifying and addressing the most relevant symptoms...
April 2015: Rambam Maimonides Medical Journal
keyword
keyword
30272
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"