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Indirect calorimetry

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https://www.readbyqxmd.com/read/29224893/external-validation-of-equations-to-estimate-resting-energy-expenditure-in-14952-adults-with-overweight-and-obesity-and-1948-adults-with-normal-weight-from-italy
#1
Giorgio Bedogni, Simona Bertoli, Alessandro Leone, Ramona De Amicis, Elisa Lucchetti, Fiorenza Agosti, Nicoletta Marazzi, Alberto Battezzati, Alessandro Sartorio
BACKGROUND & AIMS: We cross-validated 28 equations to estimate resting energy expenditure (REE) in a very large sample of adults with overweight or obesity. METHODS: 14952 Caucasian men and women with overweight or obesity and 1498 with normal weight were studied. REE was measured using indirect calorimetry and estimated using two meta-regression equations and 26 other equations. The correct classification fraction (CCF) was defined as the fraction of subjects whose estimated REE was within 10% of measured REE...
November 24, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29224176/validation-of-a-method-for-estimating-energy-expenditure-during-walking-in-middle-aged-adults
#2
Nathan Caron, Teddy Caderby, Nicolas Peyrot, Chantal Verkindt, Georges Dalleau
PURPOSE: The aim of this study was to test the validity of a method using an inertial measurement unit for estimating activity-related energy expenditure (AEE) during walking in middle-aged adults. METHODS: Twenty healthy middle-aged participants completed different treadmill walking trials with an inertial measurement unit adhered to their lower back. Gas exchange was monitored with indirect calorimetry. Mechanical data were used to estimate AEE from an algorithm developed by Bouten et al...
December 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29222882/relative-validity-of-an-indirect-calorimetry-device-for-measuring-resting-energy-expenditure-and-respiratory-quotient
#3
Xi Wang, Yuan Wang, Zenghui Ding, Guangbei Cao, Fusong Hu, Yining Sun, Zuchang Ma, Duoqi Zhou, Benyue Su
BACKGROUND AND OBJECTIVES: Resting energy expenditure (REE) and respiratory quotient (RQ) are important for optimal nutritional care. The purpose of this study was to assess the accuracy and repeatability of an indirect calorimetry device (IIM-IC-100) in the measurement of REE and RQ in healthy Chinese adults. METHODS AND STUDY DESIGN: A total of 38 healthy adults (19 male and 19 female) aged 18-52 years (25±6 years) were enrolled in this study. REE and RQ were measured by IIM-IC-100 and by VO2000, alternately and in duplicate...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29220530/impaired-lipolysis-diminished-fat-oxidation-and-metabolic-inflexibility-in-obese-girls-with-polycystic-ovary-syndrome
#4
Joon Young Kim, Hala Tfayli, Sara F Michaliszyn, Silva Arslanian
CONTEXT: Metabolic flexibility reflects the ability to switch from lipid to carbohydrate oxidation during insulin stimulation manifested in increased respiratory quotient (RQ). Despite insulin resistance in glucose metabolism in PCOS women and adolescents, little is known about adipose tissue metabolism and metabolic flexibility. OBJECTIVE: To investigate whole-body lipolysis, substrate oxidation and metabolic flexibility in obese PCOS vs. non-PCOS girls. PATIENTS/DESIGN: Twenty-one obese (BMI 32...
December 6, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29216357/parental-history-of-type-2-diabetes-abrogates-ethnic-disparities-in-key-glucoregulatory-indices
#5
Ebenezer Nyenwe, Ibiye Owei, Jim Wan, Sam Dagogo-Jack
Background: There are ethnic differences in glucoregulation and prevalence of type 2 diabetes but studies on the role of genetics in modifying ethnic effects in normoglycemic African-Americans and Caucasians are limited. Therefore, we investigated glucoregulation in normoglycemic African-Americans and Caucasians with or without parental diabetes. Design and Methods: Fifty subjects with parental diabetes (from the POP-ABC cohort) and 50 subjects without parental diabetes were matched in age, sex, ethnicity, and BMI...
December 4, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29202634/energy-cost-of-common-physical-activities-in-preschoolers
#6
Mirko Brandes, Berit Steenbock, Norman Wirsik
BACKGROUND: To determine the energy cost of common physical activities in preschoolers and to compare it with the Compendium of Energy Expenditure for Youth (CEEY). METHODS: In total, 42 children [age: 4.8 (0.8) y; body mass index: 15.3 (2.0) kg/m2; 22 boys] completed 13 common physical activities covering sedentary to vigorous intensities, while energy expenditure (EE) was measured continuously by indirect calorimetry. Activity-specific metabolic equivalents (AME) were calculated as the EE observed during each single activity divided by the EE during observed rest...
December 4, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/29199788/adaptive-thermogenesis-and-changes-in-body-composition-and-physical-fitness-in-army-cadets
#7
Juliano H Borges, Gary R Hunter, Analiza M Silva, Vagner X Cirolini, Raquel D Langer, Mauro A Páscoa, Gil Guerra, Ezequiel M Gonçalves
BACKGROUND: To analyze the association between a 34-week military training on body composition, physical fitness and compensatory changes in resting energy expenditure (REE) recognized as adaptive thermogenesis (AT). We also explored if regional body composition changes were related to AT. METHODS: Twenty-nine male army cadets, aged 17 to 22 years were tested at baseline (T0) and after 34-weeks military training (T1). Physical training was performed 5 days/week during 90 minutes/day...
December 1, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29198194/the-effects-of-diurnal-ramadan-fasting-on-energy-expenditure-and-substrate-oxidation-in-healthy-men
#8
Sana'a A Alsubheen, Mohammad Ismail, Alicia Baker, Jason Blair, Adeboye Adebayo, Liam Kelly, Vikram Chandurkar, Sukhinder Cheema, Denis R Joanisse, Fabien A Basset
The study aimed to examine the effects of diurnal Ramadan fasting (RF) on substrate oxidation, energy production, blood lipids and glucose as well as body composition. Nine healthy Muslim men (fasting (FAST) group) and eight healthy non-practicing men (control (CNT) group) were assessed pre- and post-RF. FAST were additionally assessed at days 10, 20 and 30 of RF in the morning and evening. Body composition was determined by hydrodensitometry, substrate oxidation and energy production by indirect calorimetry, blood metabolic profile by biochemical analyses and energy balance by activity tracker recordings and food log analyses...
December 4, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/29191073/using-an-allometric-equation-to-accurately-predict-the-energy-expenditure-of-children-and-adolescents-with-nonalcoholic-fatty-liver-disease
#9
Inez Martincevic, Marialena Mouzaki
BACKGROUND: Pediatric patients with nonalcoholic fatty liver disease (NAFLD) require targeted nutrition therapy that relies on calculating energy needs. Common energy equations are inaccurate in predicting resting energy expenditure (REE), influencing total energy expenditure (TEE) estimates. Equations based on allometric scaling are simple, accurate, void of subjective activity and/or stress factor bias, and they estimate TEE. OBJECTIVE: To investigate the predictive accuracy of an allometric energy equation (AEE) in predicting TEE of children and adolescents with NAFLD...
March 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29187061/accuracy-of-predictive-equations-for-energy-expenditure-in-mexicans-living-with-hiv-aids-with-and-without-antiretroviral-therapy
#10
Iván Armando Osuna-Padilla, Adriana Aguilar-Vargas, Andrea Villazón-De la Rosa, Yuria Ablanedo-Terrazas, Yetlanezi Vargas-Infante, Gustavo Reyes-Terán
INTRODUCTION: Determination of the resting energy expenditure (REE) is essential for planning nutrition therapy in patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) to help to improve their nutrition status. We aim to evaluate the agreement and accuracy of prediction equations that estimate the REE in a Mexican population with a diagnosis of HIV/AIDS with and without antiretroviral therapy (ART). METHODS: A cross-sectional study in Mexican patients with HIV/AIDS with and without ART...
February 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29180723/neuromodulation-of-orexin-neurons-reduces-diet-induced-adiposity
#11
A N Zink, P E Bunney, A A Holm, C J Billington, C M Kotz
BACKGROUND/OBJECTIVES: Low levels of orexin are associated with obesity and reduced physical activity in humans and animals. SUBJECTS/METHODS: Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) selectively activated orexin neurons in mouse lateral hypothalamus (LH) to measure effects on spontaneous physical activity (SPA). DREADD targeting was achieved by stereotaxic injection of AAV vectors into caudal lateral LH of heterozygous orexin Cre or C57/B6J mice...
November 28, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29180454/effect-of-sacubitril-valsartan-on-exercise-induced-lipid-metabolism-in-patients-with-obesity-and-hypertension
#12
Stefan Engeli, Rudi Stinkens, Tim Heise, Marcus May, Gijs H Goossens, Ellen E Blaak, Bas Havekes, Thomas Jax, Diego Albrecht, Parasar Pal, Uwe Tegtbur, Sven Haufe, Thomas H Langenickel, Jens Jordan
Sacubitril/valsartan (LCZ696), a novel angiotensin receptor-neprilysin inhibitor, was recently approved for the treatment of heart failure with reduced ejection fraction. Neprilysin degrades several peptides that modulate lipid metabolism, including natriuretic peptides. In this study, we investigated the effects of 8 weeks' treatment with sacubitril/valsartan on whole-body and adipose tissue lipolysis and lipid oxidation during defined physical exercise compared with the metabolically neutral comparator amlodipine...
November 27, 2017: Hypertension
https://www.readbyqxmd.com/read/29177598/systemic-metabolism-and-energy-consumption-after-microsurgical-clipping-and-endovascular-coiling-for-aneurysmal-subarachnoid-hemorrhage
#13
Hiroya Shimauchi-Ohtaki, Masahiko Tosaka, Toshiyuki Ohtani, Keiya Iijima, Nobuo Sasaguchi, Hideyuki Kurihara, Yuhei Yoshimoto
BACKGROUND: The postoperative metabolic states of subarachnoid hemorrhage (SAH) patients were investigated using indirect calorimetry (IDC) and various nutritional evaluations to establish any difference in perioperative metabolic and nutritional states between microsurgical and endovascular treatment. METHODS: This study included 30 acute aneurysmal SAH patients with ruptured intracranial aneurysms treated by surgical clipping (n = 16) or coil embolization (n = 14) at a single institute...
November 24, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29169857/development-and-validation-of-new-predictive-equation-for-resting-energy-expenditure-in-adults-with-overweight-and-obesity
#14
Ximena Orozco-Ruiz, Edgar Pichardo-Ontiveros, Armando R Tovar, Nimbe Torres, Isabel Medina-Vera, Federica Prinelli, Claudio L Lafortuna, Martha Guevara-Cruz
BACKGROUND & AIMS: Accurate predictive equations of resting energy expenditure (REE) are crucial in devising nutritional strategies to manage overweight/obesity, especially in countries where these are highly prevalent. REE is the most common measurement used to estimate energy requirements in the nutritional context; the most accurate method of measuring REE is indirect calorimetry (IC). However, this method is costly and often rarely feasible in many clinical settings. The objective of the present study was to develop and validate a new equation for predicting REE in adults with overweight and obesity...
November 10, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29155839/performance-of-thigh-mounted-triaxial-accelerometer-algorithms-in-objective-quantification-of-sedentary-behaviour-and-physical-activity-in-older-adults
#15
Jorgen A Wullems, Sabine M P Verschueren, Hans Degens, Christopher I Morse, Gladys L Onambélé
Accurate monitoring of sedentary behaviour and physical activity is key to investigate their exact role in healthy ageing. To date, accelerometers using cut-off point models are most preferred for this, however, machine learning seems a highly promising future alternative. Hence, the current study compared between cut-off point and machine learning algorithms, for optimal quantification of sedentary behaviour and physical activity intensities in the elderly. Thus, in a heterogeneous sample of forty participants (aged ≥60 years, 50% female) energy expenditure during laboratory-based activities (ranging from sedentary behaviour through to moderate-to-vigorous physical activity) was estimated by indirect calorimetry, whilst wearing triaxial thigh-mounted accelerometers...
2017: PloS One
https://www.readbyqxmd.com/read/29150696/impact-of-prolonged-overfeeding-on-skeletal-muscle-mitochondria-in-healthy-individuals
#16
Frederico G S Toledo, Darcy L Johannsen, Jeffrey D Covington, Sudip Bajpeyi, Bret Goodpaster, Kevin E Conley, Eric Ravussin
AIMS/HYPOTHESES: Reduced mitochondrial capacity in skeletal muscle has been observed in obesity and type 2 diabetes. In humans, the aetiology of this abnormality is not well understood but the possibility that it is secondary to the stress of nutrient overload has been suggested. To test this hypothesis, we examined whether sustained overfeeding decreases skeletal muscle mitochondrial content or impairs function. METHODS: Twenty-six healthy volunteers (21 men, 5 women, age 25...
November 17, 2017: Diabetologia
https://www.readbyqxmd.com/read/29140154/no-difference-in-young-adult-athletes-resting-energy-expenditure-when-measured-under-inpatient-or-outpatient-conditions
#17
Julia L Bone, Louise M Burke
Low energy availability can place athletes at increased risk of injury and illness and can be detected by a low metabolic rate. The lowest metabolic rate is captured at the bedside, after an overnight fast and termed inpatient REE. Measurements done in a laboratory with a shorter overnight fast are termed outpatient REE. Although important to know what the lowest energy expenditure, a bedside measure and/or 12 h fast is not always practical or logistically possible particularly when you take into account an athlete's training schedule...
November 15, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29139146/effects-of-the-sodium-glucose-cotransporter-2-sglt2-inhibitor-velagliflozin-a-new-drug-with-therapeutic-potential-to-treat-diabetes-in-cats
#18
M Hoenig, M Clark, D J Schaeffer, D Reiche
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are used in the treatment of human diabetics. They increase glucose excretion and correct hyperglycemia. We examined the investigational SGLT2 inhibitor velagliflozin in two groups of six neutered adult obese cats (equal gender distribution). Placebo (Pl) or drug (D; 1 mg/kg) was administered for 35 days. Routine blood examinations, fructosamine, beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), glucagon, adiponectin, and leptin were measured before and after treatment, also water intake, and urinary electrolytes, glucose, and volume...
November 15, 2017: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29134744/acute-oral-sodium-propionate-supplementation-raises-resting-energy-expenditure-and-lipid-oxidation-in-fasted-humans
#19
Edward S Chambers, Claire S Byrne, Karen Aspey, Yanjie Chen, Saadiyah Khan, Douglas J Morrison, Gary Frost
Short chain fatty acids (SCFAs), produced from fermentation of dietary fibre by the gut microbiota, have been suggested to modulate energy metabolism. Previous work using rodent models have demonstrated that oral supplementation of the SCFA propionate raises resting energy expenditure (REE) by promoting lipid oxidation. The objective of this study was to investigate the effects of oral sodium propionate on REE and substrate metabolism in humans. Eighteen healthy volunteers (9 females and 9 males; Age: 25±1 y; Body Mass Index: 24...
November 13, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/29133204/investigating-phase-separation-in-amorphous-solid-dispersions-via-raman-mapping
#20
Christian Luebbert, Christian Klanke, Gabriele Sadowski
The bioavailability of poorly-water-soluble active pharmaceutical ingredients (APIs) can be significantly improved by so-called amorphous solid dispersions (ASDs). However, the long-term stability of ASDs might be impaired by API recrystallization and/or amorphous phase separation (APS). So far, no methods have been reported to quantify APS in ASDs. In this work, phase-separation kinetics as well as the compositions of the two amorphous phases evolving due to APS were quantitatively determined for the first time using confocal Raman spectroscopy...
November 11, 2017: International Journal of Pharmaceutics
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