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https://www.readbyqxmd.com/read/28728306/-interpretation-of-guidance-for-establishing-the-performance-characteristics-of-in-vitro-diagnostic-devices-for-the-detection-or-detection-and-differentiation-of-high-risk-human-papillomaviruses-issued-by-food-and-drug-administration-of-united-states-and-china
#1
R M Feng, W Chen, Y L Qiao
To establish the standardization of clinical verification designs for in vitro diagnostic devices(IVDs) of human papillomavirus, China Food and Drug Administration (CFDA) and United States Food and Drug Administration (FDA) issued guidelines of detailed study designs and effectiveness evaluation for accuracy validation and clinical performance of nucleic acid detection, respectively, including triage of a typical squamous cells of undetermined significance(ASC-US) patients and validation of combined screening and preliminary screening...
July 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28728153/genetic-variants-of-cytochrome-cyp2d6-in-two-mixed-chilean-populations
#2
Mónica Acuña, Eric Pinto, Paulina Olivares, Carolina Ríos
OBJECTIVES: It is known that the interindividual and interethnic variability of the genetic polymorphisms of CYP2D6 plays an important role in the presentation of adverse drug reactions and concerning lack of therapeutic effects in humans. However, there are few data available from mixed populations of Latin America, including the Chilean. The aim of this study was therefore to estimate the frequencies of CYP2D6 variants in two samples of hospitals from the northern (Hospital San José, HSJ) and eastern (Clínica Las Condes, CLC) parts of Santiago, Chile, with different degrees of Amerindian admixture (HSJ: 34...
July 21, 2017: Human Heredity
https://www.readbyqxmd.com/read/28727993/how-do-nurse-practitioners-work-in-primary-health-care-settings-a-scoping-review
#3
REVIEW
Julian Grant, Lauren Lines, Philip Darbyshire, Yvonne Parry
OBJECTIVES: This scoping review explores the work of nurse practitioners in primary health care settings in developed countries and critiques their contribution to improved health outcomes. DESIGN: A scoping review design was employed and included development of a research question, identification of potentially relevant studies, selection of relevant studies, charting data, collating, summarising and reporting findings. An additional step was added to evaluate the methodological rigor of each study...
June 28, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28727934/phylogenomics-reveals-a-complex-evolutionary-history-of-lobed-leaf-white-oaks-in-western-north-america
#4
John D McVay, Duncan Hauser, Andrew L Hipp, Paul Manos
Quercus (oak) species hybridize in complex patterns that have yet to be fully explored with phylogenomic data. Analyses to date have recovered reasonable divergent patterns, suggesting that the impact of introgression may not always be obvious in inferred oak phylogenies. We explore this phenomenon using RADseq data for 136 samples representing 54 oak species by conducting phylogenetic analyses designed to distinguish signals of lineage diversification and hybridization, focusing on the lobed-leaf species Quercus gambelii, Q...
July 20, 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28727779/contemporary-status-of-insecticide-resistance-in-the-major-aedes-vectors-of-arboviruses-infecting-humans
#5
REVIEW
Catherine L Moyes, John Vontas, Ademir J Martins, Lee Ching Ng, Sin Ying Koou, Isabelle Dusfour, Kamaraju Raghavendra, João Pinto, Vincent Corbel, Jean-Philippe David, David Weetman
Both Aedes aegytpi and Ae. albopictus are major vectors of 5 important arboviruses (namely chikungunya virus, dengue virus, Rift Valley fever virus, yellow fever virus, and Zika virus), making these mosquitoes an important factor in the worldwide burden of infectious disease. Vector control using insecticides coupled with larval source reduction is critical to control the transmission of these viruses to humans but is threatened by the emergence of insecticide resistance. Here, we review the available evidence for the geographical distribution of insecticide resistance in these 2 major vectors worldwide and map the data collated for the 4 main classes of neurotoxic insecticide (carbamates, organochlorines, organophosphates, and pyrethroids)...
July 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28727772/description-of-an-establishment-event-by-the-invasive-asian-longhorned-beetle-anoplophora-glabripennis-in-a-suburban-landscape-in-the-northeastern-united-states
#6
Helen Hull-Sanders, Eugene Pepper, Kevin Davis, Robert Talbot Trotter
The establishment of non-native species is commonly described as occurring in three phases: arrival, establishment, and dispersal. Both arrival and dispersal by the Asian longhorned beetle (Anoplophora glabripennis Motschulsky), a xylophagous Cerambycid native to China and the Korean peninsula, has been documented for multiple locations in both North America and Europe, however the transitional phase, establishment, is not well understood for this species due to the need to rapidly remove populations to prevent dispersal and assist eradication, and the evident variation in the behavior of populations...
2017: PloS One
https://www.readbyqxmd.com/read/28727762/sexual-diversity-in-the-united-states-results-from-a-nationally-representative-probability-sample-of-adult-women-and-men
#7
Debby Herbenick, Jessamyn Bowling, Tsung-Chieh Jane Fu, Brian Dodge, Lucia Guerra-Reyes, Stephanie Sanders
In 2015, we conducted a cross-sectional, Internet-based, U.S. nationally representative probability survey of 2,021 adults (975 men, 1,046 women) focused on a broad range of sexual behaviors. Individuals invited to participate were from the GfK KnowledgePanel®. The survey was titled the 2015 Sexual Exploration in America Study and survey completion took about 12 to 15 minutes. The survey was confidential and the researchers never had access to respondents' identifiers. Respondents reported on demographic items, lifetime and recent sexual behaviors, and the appeal of 50+ sexual behaviors...
2017: PloS One
https://www.readbyqxmd.com/read/28727526/zika-and-reproductive-rights-in-brazil-challenge-to-the-right-to-health
#8
Pablo K Valente
The Zika virus epidemic rapidly spread across Brazil and Latin America, gaining international attention because of the causal relationship between Zika and birth defects. The high number of cases in Brazil has been attributed to a failure of the state to contain the epidemic and protect the affected people, especially women. Therefore, the public health crisis created by Zika exposed a stark conflict between Brazil's constitutional right to health and the long-standing violation of reproductive rights in the country...
July 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28727503/first-freshwater-bothriocephalidean-cestoda-from-tropical-south-america-closely-related-to-african-taxa
#9
Tomáš Scholz, Ricardo Massato Takemoto, Roman Kuchta
Regobothrium microhamulinum n. gen. and n. sp. (Bothriocephalidea: Bothriocephalidae) is proposed to accommodate a new cestode from flatfish Catathyridium jenynsii (Chabanaud, 1922) (Pleuronectiformes: Acharidae; type host) and another 3 freshwater fishes of the orders Characiformes, Cyprinodontiformes and Siluriformes in the Neotropical Region. The new genus is placed in the Bothriocephalidae because it possesses medioventral uterine and mediodorsal genital pores, and a follicular vitellarium. Regobothrium n...
July 20, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28727024/factors-affecting-ewe-performance-in-a-crossbred-dairy-sheep-research-flock-in-the-united-states
#10
T W Murphy, Y M Berger, P W Holman, M Baldin, R L Burgett, D L Thomas
The Spooner Agricultural Research Station operated the only dairy sheep research flock in North America through 2016. The original nondairy ewe flock was "bred up" to a crossbred dairy flock through the use of rams and semen of the East Friesian (EF) and Lacaune (LA) dairy breeds. The objective of this study was to determine the environmental and nonadditive genetic effects that influence performance of dairy ewes. The traits analyzed were 180 d adjusted milk (180d MY), fat (180d FY), and protein (180d PY) yields, percentage fat (%F) and protein (%P) in milk, lactation average somatic cell score (LSCS), and number of lambs born per ewe lambing (NLB)...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726551/extracellular-matrix-and-integrin-expression-profiles-in-fuchs-endothelial-corneal-dystrophy-cells-and-tissue-model
#11
Benjamin Goyer, Mathieu Thériault, Sébastien P Gendron, Isabelle Brunette, Patrick J Rochette, Stéphanie Proulx
Primary corneal endothelial cell cultures and 3D engineered tissue models were used to study the aberrant deposition of extracellular matrix (ECM) in a vision impairing pathology known as Fuchs endothelial corneal dystrophy (FECD). Corneal endothelial cells (CEC) were isolated from excised Descemet membranes of patients with end-stage FECD. CEC isolated from healthy corneas served as controls. Microarray gene profiling was performed on post-confluent cultures of healthy and FECD cells. Protein expression analyses were conducted on tissue models that were engineered by seeding an endothelium on previously devitalized human stromal carriers...
July 20, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28726065/automatic-referral-to-standardize-palliative-care-access-an-international-delphi-survey
#12
David Hui, Masanori Mori, Yee-Choon Meng, Sharon M Watanabe, Augusto Caraceni, Florian Strasser, Tiina Saarto, Nathan Cherny, Paul Glare, Stein Kaasa, Eduardo Bruera
PURPOSE: Palliative care referral is primarily based on clinician judgment, contributing to highly variable access. Standardized criteria to trigger automatic referral have been proposed, but it remains unclear how best to apply them in practice. We conducted a Delphi study of international experts to identify a consensus for the use of standardized criteria to trigger automatic referral. METHODS: Sixty international experts stated their level of agreement for 14 statements regarding the use of clinician-based referral and automatic referral over two Delphi rounds...
July 19, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28725662/life-satisfaction-data-in-a-developing-country-calibrando-measurement-system
#13
Lina Martínez
This paper describes one large multi-annual research project-CaliBRANDO-about subjective wellbeing in a developing country. CaliBRANDO is a life satisfaction measurement system implemented in Cali, the third largest city in Colombia, South America. Data have been collected annually since 2014 and aim at collecting comprehensive temporal information about individual-level subjective wellbeing and its relationship with government performance. CaliBRANDO is the only study in Colombia that measures subjective wellbeing in a large city in this way...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28725417/reduced-inflammation-in-expanding-populations-of-a-neotropical-bird-species
#14
Juliette Bailly, Stéphane Garnier, Aurélie Khimoun, Emilie Arnoux, Cyril Eraud, Jean-Yves Goret, Thomas Luglia, Philippe Gaucher, Bruno Faivre
The loss of regulating agents such as parasites is among the most important changes in biotic interactions experienced by populations established in newly colonized areas. Under a relaxed parasite pressure, individuals investing less in costly immune mechanisms might experience a selective advantage and become successful colonizers as they re-allocate resources to other fitness-related traits. Accordingly, a refinement of the evolution of increased competitive ability (EICA) hypothesis proposed that immunity of invasive populations has evolved toward a reduced investment in innate immunity, the most costly component of immunity, and an increased humoral immunity that is less costly...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28725377/environmental-variability-and-population-dynamics-do-european-and-north-american-ducks-play-by-the-same-rules
#15
Hannu Pöysä, Jukka Rintala, Douglas H Johnson, Jukka Kauppinen, Esa Lammi, Thomas D Nudds, Veli-Matti Väänänen
Density dependence, population regulation, and variability in population size are fundamental population processes, the manifestation and interrelationships of which are affected by environmental variability. However, there are surprisingly few empirical studies that distinguish the effect of environmental variability from the effects of population processes. We took advantage of a unique system, in which populations of the same duck species or close ecological counterparts live in highly variable (north American prairies) and in stable (north European lakes) environments, to distinguish the relative contributions of environmental variability (measured as between-year fluctuations in wetland numbers) and intraspecific interactions (density dependence) in driving population dynamics...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28725011/observed-trends-in-the-magnitude-and-persistence-of-monthly-temperature-variability
#16
Timothy M Lenton, Vasilis Dakos, Sebastian Bathiany, Marten Scheffer
Climate variability is critically important for nature and society, especially if it increases in amplitude and/or fluctuations become more persistent. However, the issues of whether climate variability is changing, and if so, whether this is due to anthropogenic forcing, are subjects of ongoing debate. Increases in the amplitude and persistence of temperature fluctuations have been detected in some regions, e.g. the North Pacific, but there is no agreed global signal. Here we systematically scan monthly surface temperature indices and spatial datasets to look for trends in variance and autocorrelation (persistence)...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724952/global-alterations-in-areas-of-suitability-for-maize-production-from-climate-change-and-using-a-mechanistic-species-distribution-model-climex
#17
Nadiezhda Y Z Ramirez-Cabral, Lalit Kumar, Farzin Shabani
At the global level, maize is the third most important crop on the basis of harvested area. Given its importance, an assessment of the variation in regional climatic suitability under climate change is critical. CliMond 10' data were used to model the potential current and future climate distribution of maize at the global level using the CLIMEX distribution model with climate data from two general circulation models, CSIRO-Mk3.0 and MIROC-H, assuming an A2 emissions scenario for 2050 and 2100. The change in area under future climate was analysed at continental level and for major maize-producing countries of the world...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724896/unprecedented-drought-over-tropical-south-america-in-2016-significantly-under-predicted-by-tropical-sst
#18
Amir Erfanian, Guiling Wang, Lori Fomenko
Tropical and sub-tropical South America are highly susceptible to extreme droughts. Recent events include two droughts (2005 and 2010) exceeding the 100-year return value in the Amazon and recurrent extreme droughts in the Nordeste region, with profound eco-hydrological and socioeconomic impacts. In 2015-2016, both regions were hit by another drought. Here, we show that the severity of the 2015-2016 drought ("2016 drought" hereafter) is unprecedented based on multiple precipitation products (since 1900), satellite-derived data on terrestrial water storage (since 2002) and two vegetation indices (since 2004)...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724448/systemic-insecticide-treatment-of-the-canine-reservoir-of-trypanosoma-cruzi-induces-high-levels-of-lethality-in-triatoma-infestans-a-principal-vector-of-chagas-disease
#19
Ariel Loza, Adrianna Talaga, Gladys Herbas, Ruben Jair Canaviri, Thalia Cahuasiri, Laura Luck, Alvaro Guibarra, Raquel Goncalves, Juan Antonio Pereira, Sonia A Gomez, Albert Picado, Louisa Alexandra Messenger, Caryn Bern, Orin Courtenay
BACKGROUND: Despite large-scale reductions in Chagas disease prevalence across Central and South America, Trypanosoma cruzi infection remains a considerable public health problem in the Gran Chaco region where vector-borne transmission persists. In these communities, peridomestic animals are major blood-meal sources for triatomines, and household presence of infected dogs increases T. cruzi transmission risk for humans. To address the pressing need for field-friendly, complementary methods to reduce triatomine infestation and interrupt T...
July 19, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28724362/prevalence-of-chronic-kidney-disease-in-peruvian-primary-care-setting
#20
Percy Herrera-Añazco, Alvaro Taype-Rondan, María Lazo-Porras, E Alberto Quintanilla, Victor Manuel Ortiz-Soriano, Adrian V Hernandez
BACKGROUND: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. METHODS: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO)...
July 19, 2017: BMC Nephrology
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