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https://www.readbyqxmd.com/read/29676154/topological-magnon-modes-in-patterned-ferrimagnetic-insulator-thin-films
#1
Yun-Mei Li, Jiang Xiao, Kai Chang
Manipulation of magnons opens an attractive direction in the future energy-efficient information processing devices. Such quasi-particles can transfer and process information free from the troublesome Ohmic loss in conventional electronic devices. Here, we propose to realize topologically protected magnon modes using the interface between the patterned ferrimagnetic insulator thin films of different configurations without the Dzyaloshinskii-Moriya interaction. The interface thus behaves like a perfect waveguide to conduct the magnon modes lying in the band gap...
April 20, 2018: Nano Letters
https://www.readbyqxmd.com/read/29672435/outcomes-in-early-versus-late-presentation-of-focal-fibrocartilaginous-dysplasia-affecting-the-upper-extremity-a-review-of-4-cases
#2
Grigory Gershkovich, David Kahan, Scott Kozin, Daniel Zlotolow
BACKGROUND: Focal fibrocartilaginous dysplasia (FFCD) is a rare disorder of the upper and lower extremities. In the distal ulna, a ligamentous tether emerging from the metaphysis crosses the physis and restricts growth, leading to deformity. Lesion excision before radiocapitellar subluxation has been shown to restore growth and allow remodeling. We review the outcomes of 4 patients with FFCD of the distal ulna after the occurrence of radiocapitellar incongruity. METHODS: This retrospective review examined 4 patients diagnosed with FFCD of the distal ulna from 2007 to 2015...
April 18, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29671820/irritability-is-common-and-is-related-to-poorer-psychosocial-outcomes-in-youth-with-functional-abdominal-pain-disorders-fapd
#3
Sarah Nelson, Erin Moorman, Michael Farrell, Natoshia Cunningham
Functional abdominal pain disorders (FAPD) are associated with increased emotional problems which, in turn, exacerbate functional impairment. However, irritability, which relates both to internalizing and externalizing problems, has not been specifically examined in these youths. Irritability may be common and adversely impact functioning in pediatric FAPD, particularly for males who are more likely to experience such symptoms. The current study examined the relationship between irritability and psychosocial and pain-related impairment in youth with FAPD...
April 19, 2018: Children
https://www.readbyqxmd.com/read/29671435/electro-wetting-of-a-nanoscale-water-droplet-on-a-polar-solid-surface-in-electric-fields
#4
Fenhong Song, Long Ma, Jing Fan, Qicheng Chen, Guangping Lei, Ben Q Li
Molecular dynamics simulations were applied to study the wetting properties of nanoscale droplets on a polar silica solid substrate subjected to constant and alternative electric fields with various field frequencies. Results show that the external applied electric fields have significant effects on the wetting of the nanoscale droplet on a polar solid substrate. The droplet spreads asymmetrically under the effect of the external applied field, and this asymmetry culminates to the maximum when the electric field equals to 0...
April 19, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29670218/the-impact-of-genome-variation-and-diet-on-the-metabolic-phenotype-and-microbiome-composition-of-drosophila-melanogaster
#5
Lisa Jehrke, Fiona A Stewart, Andrea Droste, Mathias Beller
The metabolic phenotype of an organism depends on a complex regulatory network, which integrates the plethora of intrinsic and external information and prioritizes the flow of nutrients accordingly. Given the rise of metabolic disorders including obesity, a detailed understanding of this regulatory network is in urgent need. Yet, our level of understanding is far from completeness and complicated by the discovery of additional layers in metabolic regulation, such as the impact of the microbial community present in the gut on the hosts' energy storage levels...
April 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29667523/irritability-externalizing-and-internalizing-psychopathology-in-adolescence-cross-sectional-and-longitudinal-associations-and-moderation-by-sex
#6
Kathryn L Humphreys, Sophie N F Schouboe, Katharina Kircanski, Ellen Leibenluft, Argyris Stringaris, Ian H Gotlib
Irritability is a common feature of many psychiatric disorders, including both externalizing and internalizing disorders. There is little research, however, examining associations between irritability and these symptom domains, particularly during the important developmental period of adolescence, characterized by sex differences in the prevalence of disorders. We examined the cross-sectional associations between irritability, measured with the Affective Reactivity Index, and symptoms of externalizing and internalizing domains of psychopathology, measured with the Youth Self Report, in a volunteer community sample (N = 183) of 9- to 13-year-old (M = 11...
April 18, 2018: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/29667129/elevation-of-mmp-9-levels-promotes-epileptogenesis-after-traumatic-brain-injury
#7
Barbara Pijet, Marzena Stefaniuk, Agnieszka Kostrzewska-Ksiezyk, Photini-Effie Tsilibary, Athina Tzinia, Leszek Kaczmarek
Posttraumatic epilepsy (PTE) is a recurrent seizure disorder that often develops secondary to traumatic brain injury (TBI) that is caused by an external mechanical force. Recent evidence shows that the brain extracellular matrix plays a major role in the remodeling of neuronal connections after injury. One of the proteases that is presumably responsible for this process is matrix metalloproteinase-9 (MMP-9). The levels of MMP-9 are elevated in rodent brain tissue and human blood samples after TBI. However, no studies have described the influence of MMP-9 on the development of PTE...
April 17, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29665559/semistructured-interview-for-bipolar-at-risk-states-sibars
#8
Paolo Fusar-Poli, Andrea De Micheli, Matteo Rocchetti, Marco Cappucciati, Valentina Ramella-Cravaro, Grazia Rutigliano, Ilaria Bonoldi, Philip McGuire, Irina Falkenberg
The external prognostic accuracy of Bipolar At Risk (BAR) criteria is undetermined and no psychometric tools are available to measure them. We present here three studies that overcome these limitations. Study 1 and 2 investigated the prognostic accuracy (Harrell's C) of the original BAR and revised Bipolar At Risk States (BARS) criteria respectively for the prediction of bipolar disorders, using a retrospective cohort of individuals at Clinical High Risk for Psychosis (CHR-P). Study 3 validated externally the prognostic accuracy of a newly developed Semistructured Interview of At Risk Bipolar States (SIBARS) in an independent prospective CHR-P cohort...
April 14, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29664868/active-transcutaneous-bone-conduction-implant-middle-fossa-placement-technique-in-children-with-bilateral-microtia-and-external-auditory-canal-atresia
#9
Carolina Der, Sofía Bravo-Torres, Nicolás Pons
AIM: The aim of this study is to present the middle fossa technique (MFT) as an alternative for patients who cannot undergo traditional surgery for active transcutaneous bone conduction implants (ATBCI) due to their altered anatomy or desire for future aesthetic reconstruction. DESIGN: A case series descriptive study was designed. The MFT was developed. Preoperative and postoperative information from 24 patients with external auditory canal atresia (EACA) and implanted with ATBCI was reviewed...
April 16, 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29664241/surgical-management-of-coats-disease
#10
Shunji Kusaka
Coats disease is a sporadic, chronic retinal vascular disorder with telangiectatic and aneurysmal retinal vessels, with retinal exudation and retinal detachment in severe cases. Various treatment modalities have been used, including laser therapy, cryotherapy, anti‒vascular endothelial growth factor (VEGF) therapy, and surgery. Anti-VEGF therapy seems to be effective in reducing exudative changes and is often combined with other treatment modalities. For severe cases with exudative retinal detachment, external drainage of subretinal fluid with or without vitrectomy is commonly performed, combined with laser therapy and/or cryotherapy...
March 27, 2018: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29663856/computational-insights-into-the-interaction-of-small-molecule-inhibitors-with-hri-kinase-domain
#11
Sourabh Palrecha, Dushant Lakade, Abhijeet Kulkarni, Jayanta K Pal, Manali Joshi
The heme-regulated inhibitor (HRI) kinase regulates globin synthesis in a heme-dependent manner in reticulocytes and erythroid cells in bone marrow. Inhibitors of HRI have been proposed to lead to an increased amount of hemoglobin, benefitting anemia patients. A series of indeno[1,2-c]pyrazoles were discovered to be the first known in vitro inhibitors of HRI. However, the structural mechanism of inhibition is yet to be understood. The aim of this study was to unravel the binding mechanism of these inhibitors using molecular dynamic simulations and docking...
April 17, 2018: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/29662502/sex-dependent-effects-of-developmental-lead-exposure-on-the-brain
#12
REVIEW
Garima Singh, Vikrant Singh, Marissa Sobolewski, Deborah A Cory-Slechta, Jay S Schneider
The role of sex as an effect modifier of developmental lead (Pb) exposure has until recently received little attention. Lead exposure in early life can affect brain development with persisting influences on cognitive and behavioral functioning, as well as, elevated risks for developing a variety of diseases and disorders in later life. Although both sexes are affected by Pb exposure, the incidence, manifestation, and severity of outcomes appears to differ in males and females. Results from epidemiologic and animal studies indicate significant effect modification by sex, however, the results are not consistent across studies...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29661490/amygdala-volume-mediates-the-relationship-between-externalizing-symptoms-and-daily-smoking-in-adolescence-a-prospective-study
#13
Ali Cheetham, Nicholas B Allen, Sarah Whittle, Julian Simmons, Murat Yücel, Dan I Lubman
The current study examined amygdala and orbitofrontal cortex (OFC) volumes as mediators of the relationship between externalizing symptoms and daily smoking in adolescence. Externalizing behaviors are among the most robust predictors of adolescent smoking, and there is emerging evidence that volume reductions in the amygdala and OFC are associated with risk for substance misuse as well as aggressive, impulsive, and disinhibited tendencies. Using a prospective longitudinal design, we recruited 109 adolescents who provided data on brain volume and externalizing behaviors at age 12, and on smoking at age 18...
March 9, 2018: Psychiatry research. Neuroimaging
https://www.readbyqxmd.com/read/29655486/comprehensive-simulation-on-morphological-and-mechanical-properties-of-trigger-finger-a-cadaveric-model
#14
Yu-Shiuan Cheng, Hsiao-Feng Chieh, Chien-Ju Lin, Li-Chieh Kuo, Kai-Nan An, Fong-Chin Su
Trigger finger has long been a common disorder in hand orthopedics. To clarify the unknown causative factors regarding the disease, numerous experiments were done on human cadavers, including tendon forces, tendon moment arm, mechanical properties of the pulley, gliding resistance, etc. However, most of these studies were conducted on normal fingers. As the etiology of trigger finger is still controversial on whether it is an outcome of tendon nodule or pulley scarring, in this study, a trigger finger model was built combining both the nodule created by silicone gel injection and pulley constriction by external compression...
March 30, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29655375/association-between-traumatic-stress-load-psychopathology-and-cognition-in-the-philadelphia-neurodevelopmental-cohort
#15
Ran Barzilay, Monica E Calkins, Tyler M Moore, Daniel H Wolf, Theodore D Satterthwaite, J Cobb Scott, Jason D Jones, Tami D Benton, Ruben C Gur, Raquel E Gur
BACKGROUND: Traumatic stressors during childhood and adolescence are associated with psychopathology, mostly studied in the context of post-traumatic stress disorder (PTSD) and depression. We investigated broader associations of traumatic stress exposure with psychopathology and cognition in a youth community sample. METHODS: The Philadelphia Neurodevelopmental Cohort (N = 9498) is an investigation of clinical and neurobehavioral phenotypes in a diverse (56% Caucasian, 33% African American, 11% other) US youth community population (aged 8-21)...
April 15, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29652773/a-lonely-search-risk-for-depression-when-spirituality-exceeds-religiosity
#16
Jeffrey R Vittengl
This study clarified longitudinal relations of spirituality and religiosity with depression. Spirituality's potential emphasis on internal (e.g., intrapsychic search for meaning) versus religiosity's potential emphasis on external (e.g., engagement in socially-sanctioned belief systems) processes may parallel depression-linked cognitive-behavioral phenomena (e.g., rumination and loneliness) conceptually. Thus, this study tested the hypothesis that greater spirituality than religiosity, separate from the overall level of spirituality and religiosity, predicts longitudinal increases in depression...
May 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29652578/mr-imaging-of-the-fetal-face-comprehensive-review
#17
Murali Nagarajan, Kedar G Sharbidre, Sudeep H Bhabad, Sharon E Byrd
The human face is a complex anatomic structure with an equally complex embryologic development. Derangement of the developmental process can result in various structural anomalies, which range from a mainly cosmetic deformity, such as cleft lip, to potentially life-threatening conditions such as arhinia. These anomalies (a) can occur as isolated anomalies; (b) can be associated with intracranial, spinal, or dental anomalies; or (c) can be a part of various syndromes, thus serving as diagnostic clues in such cases...
April 13, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29649258/clinician-ratings-of-the-comprehensive-assessment-of-psychopathic-personality-capp-in-a-representative-sample-of-spanish-prison-inmates-new-validity-evidence
#18
Gerardo Flórez, Ventura Ferrer, Luis S García, María R Crespo, Manuel Pérez, Pilar A Saíz, David J Cooke
The Comprehensive Assessment of Psychopathic Personality (CAPP) is a concept map of psychopathic personality disorder (PPD). The CAPP- Institutional Rating Scale (IRS) is a tool designed to assess CAPP symptoms in institutional settings. The CAPP contains 33 personality traits organized in six domains: attachment, behavioural, cognitive, dominance, emotional and self. Until now, much of the CAPP research has been conducted out of clinical, forensic and correctional settings using self-ratings. In the current study, the psychometric properties and construct validity of the CAPP-IRS were evaluated in a non-convenience sample of 204 Spanish convicts...
2018: PloS One
https://www.readbyqxmd.com/read/29643258/prevalence-of-poststroke-neurocognitive-disorders-using-national-institute-of-neurological-disorders-and-stroke-canadian-stroke-network-vascog-criteria-vascular-behavioral-and-cognitive-disorders-and-optimized-criteria-of-cognitive-deficit
#19
Mélanie Barbay, Hervé Taillia, Claudine Nédélec-Ciceri, Flavie Bompaire, Camille Bonnin, Jérôme Varvat, Françoise Grangette, Momar Diouf, Emmanuel Wiener, Jean-Louis Mas, Martine Roussel, Olivier Godefroy
BACKGROUND AND PURPOSE: The prevalence of poststroke neurocognitive disorder (NCD) has yet to be accurately determined. The primary objective of the present study was to optimize operationalization of the criterion for NCD by using an external validity criterion. METHODS: The GRECOG-VASC cohort (Groupe de Réflexion pour l'Évaluation Cognitive Vasculaire) of 404 stroke patients with cerebral infarct (91.3%) or hemorrhage (18.7%) was assessed 6 months poststroke and 1003 healthy controls, with the National Institute of Neurological Disorders and Stroke-Canadian Stroke Network standardized battery...
April 11, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29642757/associations-between-chronotype-morbidity-and-mortality-in-the-uk-biobank-cohort
#20
Kristen L Knutson, Malcolm von Schantz
Later chronotype (i.e. evening preference) and later timing of sleep have been associated with greater morbidity, including higher rates of metabolic dysfunction and cardiovascular disease (CVD). However, no one has examined whether chronotype is associated with mortality risk to date. Our objective was to test the hypothesis that being an evening type is associated with increased mortality in a large cohort study, the UK Biobank. Our analysis included 433 268 adults aged 38-73 at the time of enrolment and an average 6...
April 11, 2018: Chronobiology International
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