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https://www.readbyqxmd.com/read/29245045/relations-between-problem-behaviors-perceived-symptom-severity-and-parenting-in-adolescents-and-emerging-adults-with-asd-the-mediating-role-of-parental-psychological-need-frustration
#1
Lisa M Dieleman, Sarah S W De Pauw, Bart Soenens, Elien Mabbe, Rachel Campbell, Peter Prinzie
Research in parents of youngsters with Autism Spectrum Disorder (ASD) increasingly documents associations between children's problem behaviors and symptom severity and more dysfunctional and less adaptive parenting behaviors. However, the mechanisms underlying these associations have not been examined thoroughly. This study examines the mediating role of parental need frustration in the relation between child maladjustment (i.e., problem behavior and autism severity) and parenting behavior (i.e., controlling and autonomy-supportive parenting)...
December 12, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29243876/familial-transmission-of-externalizing-syndromes-in-extended-swedish-families
#2
Kenneth S Kendler, Henrik Ohlsson, Jan Sundquist, Kristina Sundquist
Risk for criminal behavior (CB), alcohol use disorder (AUD), and drug abuse (DA) are known to be familial. We know less about their transmission across three generations. We examined 844,109 probands born in Sweden 1980-1990, their parents, aunts/uncles, and grandparents for registration in population-based registers for CB, AUD, and DA. Mean tetrachoric relative-proband correlations (95% CIs) were highest for DA (+0.24, 0.24-0.25), followed by CB (+0.23,0.22-0.23) and AUD (+0.17, 0.16-0.17). AUD and CB were relatively stably transmitted across generations, while DA resemblance among relatives was stronger in the younger generations...
December 15, 2017: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/29243079/should-clinicians-split-or-lump-psychiatric-symptoms-the-structure-of-psychopathology-in-two-large-pediatric-clinical-samples-from-england-and-norway
#3
Lorena Fernández de la Cruz, Pablo Vidal-Ribas, Nada Zahreddine, Børge Mathiassen, Per Håkan Brøndbo, Emily Simonoff, Robert Goodman, Argyris Stringaris
It has been suggested that the structure of psychiatric phenomena can be reduced to a few symptom dimensions. These proposals, mainly based on epidemiological samples, may not apply to clinical populations. We tested the structure of psychiatric symptoms across two pediatric clinical samples from England (N = 8434) and Norway (N = 5866). Confirmatory factor analyses of the parent-reported Strengths and Difficulties Questionnaire (SDQ) evaluated the relative fit of several models, including a first-order model, a second-order model with the widely-established broad symptom dimensions of internalizing-externalizing, and two bi-factor models capturing a general psychopathology factor...
December 14, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29242499/high-internal-noise-and-poor-external-noise-filtering-characterize-perception-in-autism-spectrum-disorder
#4
Woon Ju Park, Kimberly B Schauder, Ruyuan Zhang, Loisa Bennetto, Duje Tadin
An emerging hypothesis postulates that internal noise is a key factor influencing perceptual abilities in autism spectrum disorder (ASD). Given fundamental and inescapable effects of noise on nearly all aspects of neural processing, this could be a critical abnormality with broad implications for perception, behavior, and cognition. However, this proposal has been challenged by both theoretical and empirical studies. A crucial question is whether and how internal noise limits perception in ASD, independently from other sources of perceptual inefficiency, such as the ability to filter out external noise...
December 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29242034/dendritic-cells-in-the-regulation-of-immunity-and-inflammation
#5
REVIEW
Cheng Qian, Xuetao Cao
As potent antigen-presenting cells, dendritic cells (DCs) comprise the most heterogeneous cell population with significant cellular phenotypic and functional plasticity. They form a sentinel network to modulate immune responses, since intrinsic cellular mechanisms and complex external, environmental signals endow DCs with the distinct capacity to induce protective immunity or tolerance to self. Interactions between DCs and other cells of the immune system mediate this response. This interactive response depends on DC maturation status and subtype, as well as the microenvironment of the tissue location and DC-intrinsic regulators...
December 11, 2017: Seminars in Immunology
https://www.readbyqxmd.com/read/29241345/effects-of-attentional-focus-on-motor-learning-in-children-with-autism-spectrum-disorder
#6
Andy Cy Tse
Inability to acquire a new motor skill is a common motor difficulty in children with autism spectrum disorder. The purpose of this study is to examine whether the motor learning benefits of an external focus of attention for typically developing children and children with intellectual disabilities could also be applied to children with autism spectrum disorder. Children ( N = 65; mean age = 10.01 years) diagnosed with high-functioning autism spectrum disorder were randomly assigned into one of the three groups: external focus ( n = 22), internal focus ( n = 22), and control ( n = 21)...
December 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29240039/an-overview-of-low-back-pain-and-occupational-exposures-to-whole-body-vibration-and-mechanical-shocks
#7
Massimo Bovenzi, Marianne Schust, Marcella Mauro
This paper offers an overview of the relation of low back pain (LBP) to occupational exposures to whole-body vibration (WBV) and mechanical shocks. LBP is a condition of multifactorial origin and is a very common health problem in the general population. Among occupational risk factors, epidemiological studies of driving occupations have provided evidence for strong associations between LBP and occupational exposures to WBV and mechanical shocks. Since it is hard to separate the contribution of WBV exposure to disorders in the lower back from that of other individual, ergonomic or psychosocial risk factors, a quantitative exposure-response relationship for WBV cannot be outlined precisely...
December 14, 2017: La Medicina del Lavoro
https://www.readbyqxmd.com/read/29239206/the-reliability-and-validity-of-the-inventory-of-callous-unemotional-traits-a-meta-analytic-review
#8
Elise M Cardinale, Abigail A Marsh
In the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, a Limited Prosocial Emotions specifier was added to the conduct disorder diagnostic criteria to designate a subgroup of children who exhibit callous unemotional (CU) traits. The Inventory of Callous Unemotional Traits (ICU) is the only dedicated measure of CU traits and was influential in the development of the Limited Prosocial Emotions specifier. Despite its role in the research and diagnosis of CU traits, some questions have persisted regarding the internal consistency and validity of the ICU and its three subscales: callous, uncaring, and unemotional...
December 1, 2017: Assessment
https://www.readbyqxmd.com/read/29238825/association-of-cumulative-childhood-adversity-and-adolescent-violent-offending-with-suicide-in-early-adulthood
#9
Emma Björkenstam, Anders Hjern, Charlotte Björkenstam, Kyriaki Kosidou
Importance: Childhood adversity (CA) is associated with an increased risk of suicide in young adulthood that might be explained by maladaptive trajectories during adolescence. Although adolescent violent offending is linked with suicide, little is known about its role in the association between CA and suicide. Objective: To examine whether adolescent violent offending mediates the association between CA and suicide in early adulthood. Design, Setting, and Participants: This population-based, longitudinal cohort study with a follow-up time spanning 5 to 9 years included 476 103 individuals born in Sweden between 1984 and 1988...
December 13, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/29238818/multiscale-poroviscoelastic-compressive-properties-of-mouse-supraspinatus-tendons-are-altered-in-young-and-aged-mice
#10
Brianne Connizzo, Alan Grodzinsky
Rotator cuff disorders are one of the most common causes of shoulder pain and disability in the aging population but, unfortunately, the etiology is still unknown. One factor thought to contribute to the progression of disease is the external compression of the rotator cuff tendons, which can be significantly increased by age-related changes such as muscle weakness and poor posture. The objective of this study was to investigate the baseline compressive response of tendon and determine how this response is altered during maturation and aging...
December 13, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29238508/effectiveness-of-teaching-cognitive-behavioral-techniques-on-locus-of-control-in-hemodialysis-patients
#11
Mohammad Mehrtak, Shahram Habibzadeh, Esmaeil Farzaneh, Abdollah Rjaei-Khiavi
Background: Many of the cognitive behavioral models and therapeutic protocols developed so far for psychological disorders and chronic diseases have proved effective through clinical research. Objective: This study aimed to determine the effectiveness of teaching cognitive-behavioral techniques on locus of control in hemodialysis patients. Methods: This controlled clinical trial study was conducted in 2015 with 76 patients selected by census and treated with a hemodialysis machine in the dialysis department of Vali-Asr Hospital in the city of Meshkinshahr...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29238235/oppositional-defiant-disorder-current-insight
#12
REVIEW
Abhishek Ghosh, Anirban Ray, Aniruddha Basu
Oppositional defiant disorder (ODD) is diagnosed broadly on the basis of frequent and persistent angry or irritable mood, argumentativeness/defiance, and vindictiveness. Since its inception in the third Diagnostic and Statistical Manual of Mental Disorders, epidemiological and longitudinal studies have strongly suggested a distinct existence of ODD that is different from other closely related externalizing disorders, with different course and outcome and possibly discrete subtypes. However, several issues, such as symptom threshold, dimensional versus categorical conceptualization, and sex-specific symptoms, are yet to be addressed...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/29238102/prevention-and-prediction-of-postoperative-bowel-bladder-disorder-using-an-anal-plug-electrode-with-tc-msep-monitoring-during-spine-surgery
#13
Kazuyoshi Kobayashi, Kei Ando, Hideki Yagi, Kenyu Ito, Mikito Tsushima, Masayoshi Morozumi, Satoshi Tanaka, Masaaki Machino, Kyotaro Ota, Yukihiro Matsuyama, Naoki Ishiguro, Shiro Imagama
A retrospective study was performed to examine the efficacy of intraoperative monitoring of the external anal sphincter (EAS) muscle-evoked potential after a transcranial muscle-action potential (Tc-MsEP) in spinal cord surgery, and to evaluate alarm points for EAS waveform deterioration related to postoperative bowel bladder disorder (BBD). BBD is caused by damage to the hypogastric, pelvic, and pudendal nerves and leads to a significant reduction in quality of life. Intraoperative Tc-MsEP monitoring using the EAS is common to prevent neurological deficit, but the relationship of BBD with intraoperative monitoring of the EAS has not been examined...
November 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29234956/work-participation-among-employees-with-common-mental-disorders-a-meta-synthesis
#14
REVIEW
Cecilie Nørby Thisted, Claus Vinther Nielsen, Merete Bjerrum
Purpose The aim was to aggregate knowledge about the opportunities, challenges and need for support employees with common mental disorders experience in relation to work participation in order to develop recommendations for practice. Methods A meta-synthesis was conducted using a meta-aggregative approach to accurately and reliably present findings that could be used to meet our aim. Qualitative inductive content analysis was used to analyze and synthesize the findings. Results In all, 252 findings were extracted from 16 papers, and six categories were generated and aggregated into two synthesized findings...
December 12, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/29234932/emotion-coregulation-processes-between-mothers-and-their-children-with-and-without-autism-spectrum-disorder-associations-with-children-s-maladaptive-behaviors
#15
Valentina Valentovich, Wendy A Goldberg, Dana Rose Garfin, Yuqing Guo
A dyadic microanalysis approach was used to examine emotion coregulation processes in mother-child interactions in relation to children's maladaptive behaviors. Seventy-two mother-child dyads (46 children with Autism Spectrum Disorder (ASD); 26 neurotypical children) were previously videotaped in a semi-structured play procedure at home and mothers reported on children's internalizing and externalizing behaviors. Mother-child interactions were reliably coded in 5-second intervals and analyzed using Space State Grid software...
December 12, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29234670/mitochondrial-energy-metabolism-is-required-for-lifespan-extension-by-the-spastic-paraplegia-associated-protein-spartin
#16
Julia Ring, Patrick Rockenfeller, Claudia Abraham, Jelena Tadic, Michael Poglitsch, Katherina Schimmel, Julia Westermayer, Simon Schauer, Bettina Achleitner, Christa Schimpel, Barbara Moitzi, Gerald N Rechberger, Stephan J Sigrist, Didac Carmona-Gutierrez, Guido Kroemer, Sabrina Büttner, Tobias Eisenberg, Frank Madeo
Hereditary spastic paraplegias, a group of neurodegenerative disorders, can be caused by loss-of-function mutations in the protein spartin. However, the physiological role of spartin remains largely elusive. Here we show that heterologous expression of human or Drosophila spartin extends chronological lifespan of yeast, reducing age-associated ROS production, apoptosis, and necrosis. We demonstrate that spartin localizes to the proximity of mitochondria and physically interacts with proteins related to mitochondrial and respiratory metabolism...
November 30, 2017: Microbial Cell
https://www.readbyqxmd.com/read/29233804/end-user-and-implementer-experiences-of-mhealth-technologies-for-noncommunicable-chronic-disease-management-in-young-adults-systematic-review
#17
REVIEW
Helen Slater, Jared M Campbell, Jennifer N Stinson, Megan M Burley, Andrew M Briggs
BACKGROUND: Chronic noncommunicable diseases (NCDs) such as asthma, diabetes, cancer, and persistent musculoskeletal pain impose an escalating and unsustainable burden on young people, their families, and society. Exploring how mobile health (mHealth) technologies can support management for young people with NCDs is imperative. OBJECTIVE: The aim of this study was to identify, appraise, and synthesize available qualitative evidence on users' experiences of mHealth technologies for NCD management in young people...
December 12, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29232631/ambiguous-genitalia-a-social-dilemma-in-bangladesh-a-case-report
#18
Mohiuddin Ahsanul Kabir Chowdhury, Rashidul Anwar, Arnab Saha
INTRODUCTION: Ambiguous Genitalia is a form of birth defect in which sex of the newborn cannot be readily distinguishable because of atypical appearance of the external genitalia. CASE REPORT-CLINICAL FINDINGS: The patient, an 8 months old baby, was identified as a female baby since birth; but, some senior members of their neighborhood raised confusion regarding sex differentiation of the child. On examination, there was enlarged clitoris or micropenis, bifid scrotum or labioscrotal fold, and separate presence of urethral and vaginal orifices...
December 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29231330/-hypothesis-of-sinew-meridian-system
#19
Nongyu Liu
The author provides the hypothesis on the "sinew-meridian system" in terms of the physiology, pathology, diagnosis and treatment of meridians and sinew-meridians. Meridians are nourished with blood and sinew-meridians are softened with yang qi. Meridians are circulated in linear form and sinew-meridians are distributed in centripetal state. Meridians are communicated externally and internally and sinew-meridians are connected with tendons and bones. Meridians pertain to zangfu organs and sinew-meridians stabilize zangfu organs...
January 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29230398/insulin-signaling-deficiency-produces-immobility-in-caenorhabditis-elegans-that-models-diminished-motivation-states-in-man-and-responds-to-antidepressants
#20
Julie Dagenhardt, Angeline Trinh, Halen Sumner, Jeffrey Scott, Eric Aamodt, Donard S Dwyer
Defects in insulin signaling have been reported in schizophrenia and major depressive disorder, which also share certain negative symptoms such as avolition, anhedonia, and apathy. These symptoms reflect diminished motivational states, which have been modeled in rodents as increased immobility in the forced swimming test. We have discovered that loss-of-function mutations in the insulin receptor (daf-2) and syntaxin (unc-64) genes in Caenorhabditis elegans, brief food deprivation, and exposure to DMSO produce immobility and avolition in non-dauer adults...
November 2017: Molecular Neuropsychiatry
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