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Depression and obesity

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https://www.readbyqxmd.com/read/29331532/high-fat-diet-mediates-anxiolytic-like-behaviors-in-a-time-dependent-manner-through-the-regulation-of-sirt1-in-the-brain
#1
Liu Xu, Shuang Xu, Lifang Lin, Xi Gu, Congcong Fu, Yingying Fang, Xiaowen Li, Xuemin Wang
The consumption of a high-fat diet (HFD) and obesity have been associated not only with metabolic diseases but also with neuropsychiatric diseases, such as depression and anxiety. However, results on the effects of an HFD on anxiety are controversial, since both anxiogenic and anxiolytic effects have been reported. In this study, we evaluated the effects of both short- and long-term intake of an HFD on anxiety-like behaviors. To explore the impact of time on the association between an HFD and anxiety, mice were fed with an HFD for 4 weeks or 12 weeks...
January 10, 2018: Neuroscience
https://www.readbyqxmd.com/read/29326489/ondansetron-ameliorates-depression-associated-with-obesity-in-high-fat-diet-fed-experimental-mice-an-investigation-based-on-the-behavioral-biochemical-and-molecular-approach
#2
Yeshwant Kurhe, Radhakrishnan Mahesh
INTRODUCTION: Obesity is an important risk factor for depression as more than half of the obese population is susceptible for depression at double rate. Our earlier studies reported the antidepressant potential of 5-HT3 receptor antagonist, ondansetron (OND) in depression associated obesity using behavioral tasks. The present research work is aimed to evaluate the effect of OND on depression associated with obesity with special emphasis on biochemical and molecular mechanisms such as hippocampal brain-derived neurotrophic factor (BDNF), cyclic adenosine monophosphate (cAMP), 5-hydroxytryptamine (5-HT), hippocampal histological examination and immunohistochemical expression of p53 proteins...
July 2017: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/29326031/depressive-symptoms-and-poorer-performance-on-the-stroop-task-are-associated-with-weight-gain
#3
Emma J Stinson, Jonathan Krakoff, Marci E Gluck
OBJECTIVE: Executive function impairments and depression are associated with obesity but whether they predict weight gain is unclear. METHODS: Forty-six individuals (35m, 37±10y) completed the Stroop Task, Iowa Gambling Task (IGT), Wisconsin Card Sorting Task (WCST), Inventory for Depressive Symptomatology (IDS-SR), Physical Anhedonia Scale (PAS), and Perceived Stress Scale (PSS). Body composition (DXA) and fasting glucose were also measured. Data from return visits were used to assess changes in weight...
January 8, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29322140/development-of-antioxidant-gliadin-particle-stabilized-pickering-high-internal-phase-emulsions-hipes-as-oral-delivery-systems-and-the-in-vitro-digestion-fate
#4
F Z Zhou, T Zeng, S W Yin, C H Tang, D B Yuan, X Q Yang
In this paper, we demonstrate for the first time the use of gliadin particles to structure algal oil (rich in DHA) and to exert chemical stability against lipid oxidation via the Pickering high internal phase emulsion (HIPE) strategy. The gliadin/chitosan colloid particles (GCCPs) were effectively adsorbed and anchored at the algal oil-water interface. Concomitantly, the particle-coated droplets as building blocks constructed a percolating 3D-network framework, endowing Pickering HIPEs with viscoelastic and self-supporting attributes...
January 11, 2018: Food & Function
https://www.readbyqxmd.com/read/29320364/cardiometabolic-effects-of-psychotropic-medications
#5
REVIEW
Oluchi Abosi, Sneha Lopes, Samantha Schmitz, Jess G Fiedorowicz
Background Many psychiatric disorders including schizophrenia, bipolar disorder and major depression convey an excess burden of cardiovascular morbidity and mortality. The medications used to treat these conditions may further adversely affect cardiovascular risk and exacerbate health disparities for vulnerable populations. There is a clinical need to appreciate the cardiometabolic adverse effects of psychotropic medications. Methods This paper reviews the most relevant cardiometabolic effects of psychotropic medications, organized around the components of metabolic syndrome...
January 10, 2018: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/29318645/endometriosis-increased-the-risk-of-bladder-pain-syndrome-interstitial-cystitis-a-population-based-study
#6
Chia-Chang Wu, Shiu-Dong Chung, Herng-Ching Lin
OBJECTIVE: Previous studies have suggested an association between bladder pain syndrome/interstitial cystitis (BPS/IC) and endometriosis. However, no nation-wide population study has yet reported an association between them. In this study, we examined the risk of BPS/IC among subjects with endometriosis during a 3-year follow-up in Taiwan using a population-based dataset. STUDY DESIGN: This study comprised 9191 subjects with endometriosis, and 27 573 subjects randomly selected as controls...
January 10, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29318342/group-cognitive-behavioural-therapy-and-weight-regain-after-diet-in-type-2-diabetes-results-from-the-randomised-controlled-power-trial
#7
Kirsten A Berk, Hanneke I M Buijks, Adrie J M Verhoeven, Monique T Mulder, Behiye Özcan, Adriaan van 't Spijker, Reinier Timman, Jan J Busschbach, Eric J Sijbrands
AIMS/HYPOTHESIS: Weight-loss programmes for adults with type 2 diabetes are less effective in the long term owing to regain of weight. Our aim was to determine the 2 year effectiveness of a cognitive behavioural group therapy (group-CBT) programme in weight maintenance after diet-induced weight loss in overweight and obese adults with type 2 diabetes, using a randomised, parallel, non-blinded, pragmatic study design. METHODS: We included 158 obese adults (median BMI 36...
January 9, 2018: Diabetologia
https://www.readbyqxmd.com/read/29317379/effect-of-a-gender-tailored-ehealth-weight-loss-program-on-the-depressive-symptoms-of-overweight-and-obese-men-pre-post-study
#8
Myles D Young, Philip J Morgan
BACKGROUND: Obesity and depression are of two of the largest contributors to the global burden of disease in men. Although lifestyle behavior change programs can improve participants' weight and depressive symptoms, the evidence is limited by a lack of male participants and a reliance on face-to-face treatment approaches, which are not accessible or appealing for many men. OBJECTIVE: This study examined the effect of a gender-tailored electronic health (eHealth) program on the depressive symptoms of a community sample of overweight and obese men with or without depression...
January 9, 2018: JMIR Mental Health
https://www.readbyqxmd.com/read/29315965/do-health-related-factors-predict-major-depression-a-longitudinal-epidemiologic-study
#9
Xiao Chi Zhang, Marcella L Woud, Eni S Becker, Jürgen Margraf
Major depressive disorder (MDD) is a leading cause of global disease burden. Hence, examining the role of risk and protective factors for MDD is an important target in psychological research. Various studies showed that obesity, smoking, and alcohol consumption are related to depressive symptoms. In contrast, physical activity has been found to be a protective factor. The present population-based study tested whether these health-related factors are prospectively associated with incidence of MDD. Data were taken from the Dresden Predictor Study, which was designed to investigate risk and protective factors of mental health in young women...
January 8, 2018: Clinical Psychology & Psychotherapy
https://www.readbyqxmd.com/read/29311748/integrated-analysis-of-gene-expression-differences-in-twins-discordant-for-disease-and-binary-phenotypes
#10
Sivateja Tangirala, Chirag J Patel
While both genes and environment contribute to phenotype, deciphering environmental contributions to phenotype is a challenge. Furthermore, elucidating how different phenotypes may share similar environmental etiologies also is challenging. One way to identify environmental influences is through a discordant monozygotic (MZ) twin study design. Here, we assessed differential gene expression in MZ discordant twin pairs (affected vs. non-affected) for seven phenotypes, including chronic fatigue syndrome, obesity, ulcerative colitis, major depressive disorder, intermittent allergic rhinitis, physical activity, and intelligence quotient, comparing the spectrum of genes differentially expressed across seven phenotypes individually...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29309852/the-impact-of-chronic-stress-on-the-predictors-of-acute-stress-induced-eating-in-women
#11
Rebecca R Klatzkin, Allie Baldassaro, Ellery Hayden
Chronic stress is associated with palatable food intake and thus, the development of obesity. This may be due to chronic stress disrupting the regulatory effects of the hypothalamic pituitary adrenal (HPA) axis on stress-induced eating. Thus, the primary objective of the current study was to investigate how chronic stress (CS) and cortisol stress reactivity affect eating behaviors following acute stress. Exploratory analyses also sought to determine the distinct psychophysiological factors driving acute stress-induced eating in women with high versus low CS...
January 5, 2018: Appetite
https://www.readbyqxmd.com/read/29309688/genome-wide-analysis-of-starvation-selected-drosophila-melanogaster-a-genetic-model-of-obesity
#12
Christopher M Hardy, Molly K Burke, Logan J Everett, Mira V Han, Kathryn M Lantz, Allen G Gibbs
Experimental evolution affords the opportunity to investigate adaptation to stressful environments. Studies combining experimental evolution with whole-genome resequencing have provided insight into the dynamics of adaptation and a new tool to uncover genes associated with polygenic traits. Here, we selected for starvation resistance in populations of Drosophila melanogaster for over 80 generations. In response, the starvation-selected lines developed an obese condition, storing nearly twice the level of total lipids than their unselected controls...
January 1, 2018: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29309200/risk-factors-for-infection-after-shoulder-arthroscopy-in-a-large-medicare-population
#13
Jourdan M Cancienne, Stephen F Brockmeier, Eric W Carson, Brian C Werner
BACKGROUND: Shoulder arthroscopy is well established as a highly effective and safe procedure for the treatment for several shoulder disorders and is associated with an exceedingly low risk of infectious complications. Few data exist regarding risk factors for infection after shoulder arthroscopy, as previous studies were not adequately powered to evaluate for infection. PURPOSE: To determine patient-related risk factors for infection after shoulder arthroscopy by using a large insurance database...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29306907/new-aspects-in-the-pathomechanism-of-diseases-of-civilization-particularly-psychosomatic-disorders-part-2-chronic-hypocapnia-and-hypercapnia-in-the-medical-practice
#14
Andras Sikter, Zoltan Rihmer, Roberto de Guevara
The authors seek to find new connections between recent results of biology and older theories. This paper aims to assemble the jigsaw puzzle. The theoretical background of the hypothesis was described in the previous issue of the journal (Sikter et al. 2017a). Human stress response often coexists with persistent hypocapnia or hypercapnia - developing via psychosomatic pathomechanism - which can lead to mental and psychosomatic illnesses. Chronic hypocapnia mainly generates hyperarousal disorders which may be reversible for an extended time, however, vicious cycles may start when hypoxia and/or severe somatic diseases are simultaneously present (commonly in the elderly), which conditions often end with death without medical help...
September 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29306622/commonly-occurring-adverse-birth-outcomes-and-maternal-depression-a-longitudinal-study
#15
A M Kingsbury, M Plotnikova, J M Najman
OBJECTIVES: Little is known about whether commonly occurring adverse birth outcomes have a long-term impact on the mental health of mothers. The aim of this study was to investigate whether commonly occurring adverse birth outcomes predicted mothers' depressive-symptom trajectories over a 27-year period following the birth of a baby. STUDY DESIGN: Longitudinal study. METHODS: Participants comprised a sub-group of women from the longitudinal cohort of the Mater and University of Queensland Study of Pregnancy...
January 4, 2018: Public Health
https://www.readbyqxmd.com/read/29306174/correlations-between-suicide-rates-and-the-prevalence-of-suicide-risk-factors-among-korean-adolescents
#16
Subin Park, Hyesue Jang
We examined whether annual changes in the prevalence of suicide risk factors are related to annual changes in suicide rates among male and female adolescents in South Korea. Data from the Korean Youth Risk Behavior Web-based Survey (2005-2015) were used to obtain the annual prevalence of psychological and health-related risk factors among Korean adolescents. Mortality data from the Korean National Statistical Office (NSO) were used to obtain annual suicide rates among Korean adolescents aged 15-19 years. For male adolescents, there were significant positive correlations between suicide rate and the rate of depressive mood, suicidal ideation, suicide attempt, drinking, and smoking and negative correlations between suicide rate and the rate of self-perceived healthiness, obesity, and being physically active...
December 24, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29300416/the-association-between-bmi-and-different-frailty-domains-a-u-shaped-curve
#17
M L Rietman, D L van der A, S H van Oostrom, H S J Picavet, M E T Dollé, H van Steeg, W M M Verschuren, A M W Spijkerman
OBJECTIVES: Previous studies showed a U-shaped association between BMI and (physical) frailty. We studied the association between BMI and physical, cognitive, psychological, and social frailty. Furthermore, the overlap between and prevalence of these frailty domains was examined. DESIGN: Cross-sectional study. SETTING: The Doetinchem Cohort Study is a longitudinal population-based study starting in 1987-1991 examining men and women aged 20-59 with follow-up examinations every 5 yrs...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29298611/prevalence-of-obesity-prediabetes-and-diabetes-in-sexual-minority-men-results-from-the-2014-behavioral-risk-factor-surveillance-system
#18
Kelley Newlin Lew, Caroline Dorsen, Thomas Long
Purpose The purpose of this study is to assess the prevalence and related odds ratios for obesity, prediabetes, and diabetes in sexual minority men (SMM) in relation to straight men. Methods A secondary analysis of 2014 Behavioral Risk Factor Surveillance System data from 19 states (n = 53 542) was conducted. Weighted means and standard errors were computed to estimate prevalence rates of obesity, prediabetes, and diabetes across male sexual orientation groups, respectively. Unadjusted and adjusted (demographics, depression, and health care access factors) weighted logistic regression models were developed...
January 1, 2018: Diabetes Educator
https://www.readbyqxmd.com/read/29298365/associations-of-prepregnancy-morbid-obesity-and-prenatal-depression-with-gestational-weight-gain
#19
Hema Chagarlamudi, Juhee Kim, Edward Newton
OBJECTIVES: Pregnancy outcomes and infant growth and development are influenced by various prenatal and postnatal factors. Gestational weight gain (GWG) is an important indicator of pregnancy management and outcomes. Information about the interaction between prenatal obesity and depression on GWG among low-income women is limited. There also is a lack of information about morbid obesity and GWG. The purpose of this study was to examine the associations of prepregnancy weight status, including morbid obesity as a separate group, and prenatal depression with GWG using electronic medical records in an academic prenatal clinic serving a largely low-income population...
January 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29298287/polysomnography-based-diagnosis-in-mexican-adult-patients-with-obstructive-sleep-apnea-syndrome-osas-clinical-suspicion
#20
Edgar Arrazola-Cortés, Josefina Hernández-Cervantes, Brenda González-Pérez, Sergio Sauri-Suárez, Luz Berenice López-Hernández, Christian Gabriel Toledo-Lozano, Vanessa Orellana-Villazón, Sofía Lizeth Alcaraz-Estrada, Silvia García
INTRODUCTION: Obstructive sleep apnea syndrome (OSA) occurs in 2-4% of adults, increasing by 2.5 times the risk of sudden death. OBJECTIVE: Establish the concordance of the clinical diagnostic and electrical diagnosis in an adult series that underwent polysomnography. MATERIALS AND METHODS: Patients with sleep disorders that underwent consecutively polysomnography recording. RESULTS: In this study, 51 subjects from 24 to 77 years old (54...
December 4, 2017: Neuro Endocrinology Letters
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