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https://www.readbyqxmd.com/read/28930926/fractures-of-the-nasal-bones-is-external-splinting-really-warranted
#1
Ourania Schoinohoriti, Dimosthenis Igoumenakis, George Rallis
BACKGROUND: It has been advocated that reduction of nasal bone fractures should be followed by internal packing and/or external splinting. Despite the ample literature concerning the advantages and limitations of various splint types, the necessity and effectiveness of external splinting has not been well documented. OBJECTIVE: To present the authors' experience and review the literature on treatment of nasal bone fractures, focusing on the indications and effectiveness of external splinting following closed reduction...
September 19, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28930036/role-for-laparoscopy-in-the-management-of-bile-duct-injuries
#2
Vaibhav Gupta, Shiva Jayaraman
Common bile duct (CBD) injury is the most serious complication of laparoscopic cholecystectomy. Recently, laparoscopic techniques have been used in the management of postoperative bile leak and CBD injury; this literature has not been reviewed. We reviewed the literature on CBD injury, the approach to its diagnosis and management, and reports of laparoscopic management techniques. We combined this review with our experience in laparoscopic methods to highlight diagnostic and therapeutic options. Laparoscopic techniques can be used to prevent, diagnose and treat CBD injuries...
September 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28929237/underground-anemotactic-orientation-in-leaf-cutting-ants-perception-of-airflow-and-experience-dependent-choice-of-airflow-direction-during-digging
#3
Florian Halboth, Flavio Roces
Air exchange between the large nests of Atta vollenweideri leaf-cutting ants and the environment strongly relies on a passive, wind-induced ventilation mechanism. Air moves through nest tunnels and airflow direction depends on the location of the tunnel openings on the nest mound. We hypothesized that ants might use the direction of airflow along nest tunnels as orientation cue in the context of climate control, as digging workers might prefer to broaden or to close tunnels with inflowing or outflowing air in order to regulate nest ventilation...
September 19, 2017: Die Naturwissenschaften
https://www.readbyqxmd.com/read/28929060/laser-assisted-double-layer-endoscopic-repair-of-laryngeal-clefts-our-experience-in-11-cases
#4
Danah Aljomah, Jaber Alshammari
Laryngeal cleft is a rare congenital malformation of the respiratory tract leading to a high level of morbidity and mortality, recently being diagnosed with increased frequency. Management throughout the years included medical and surgical. The open surgical technique is more commonly used although it has higher risk and need longer post-operative care. Recently surgical endoscopic repair was introduced using different techniques. To evaluate the clinical features of infants and children presenting with laryngeal clefts, and review endoscopic management modality especially the technique and results of repair using double-layer (2 layers) technique...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28929023/a-dark-past-a-restrained-present-and-an-apocalyptic-future-time-perspective-personality-and-life-satisfaction-among-anorexia-nervosa-patients
#5
Danilo Garcia, Alexandre Granjard, Suzanna Lundblad, Trevor Archer
BACKGROUND: Despite reporting low levels of well-being, anorexia nervosa patients express temperament traits (e.g., extraversion and persistence) necessary for high levels of life satisfaction. Nevertheless, among individuals without eating disorders, a balanced organization of the flow of time, influences life satisfaction beyond temperamental dispositions. A balanced time perspective is defined as: high past positive, low past negative, high present hedonistic, low present fatalistic, and high future...
2017: PeerJ
https://www.readbyqxmd.com/read/28928640/hdac3-inhibitor-rgfp966-modulates-neuronal-memory-for-vocal-communication-signals-in-a-songbird-model
#6
Mimi L Phan, Mark M Gergues, Shafali Mahidadia, Jorge Jimenez-Castillo, David S Vicario, Kasia M Bieszczad
Epigenetic mechanisms that modify chromatin conformation have recently been under investigation for their contributions to learning and the formation of memory. For example, the role of enzymes involved in histone acetylation are studied in the formation of long-lasting memories because memory consolidation requires gene expression events that are facilitated by an open state of chromatin. We recently proposed that epigenetic events may control the entry of specific sensory features into long-term memory by enabling transcription-mediated neuronal plasticity in sensory brain areas...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28928612/human-herpesvirus-6-induced-inflammatory-cardiomyopathy-in-immunocompetent-children
#7
REVIEW
Surabhi Reddy, Eva Eliassen, Gerhard R Krueger, Bibhuti B Das
Over the last decade, human herpesvirus 6 (HHV-6) has been implicated in the etiology of pediatric myocarditis and subsequent dilated cardiomyopathy (DCM). This review provides an overview of recent literature investigating the pathophysiological relevance of HHV-6 in inflammatory cardiomyopathy. We examined 11 cases of previously published pediatric myocarditis and/or DCM associated with HHV-6 and also our experience of detection of virus particles in vascular endothelium of HHV-6 positive endomyocardial biopsy tissue by electron microscopy...
September 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28928355/role-of-endoscopy-in-the-management-of-boerhaave-syndrome
#8
Juan Ignacio Tellechea, Jean-Michel Gonzalez, Pablo Miranda-García, Adrian Culetto, Xavier Benoit D'Journo, Pascal Alexandre Thomas, Marc Barthet
Boerhaave syndrome (BS) is a spontaneous esophageal perforation which carries high mortality. Surgical treatment is well established, but the development of interventional endoscopy has proposed new therapies. We expose our experience in a Gastrointestinal and Endoscopy Unit. With a retrospective, observational, open-label, single center, consecutive case series. All patients diagnosed with BS who were managed in our center were included. Treated conservatively, endoscopically or surgically, according to their clinical condition and lesion presentation...
September 20, 2017: Clinical Endoscopy
https://www.readbyqxmd.com/read/28928327/the-technique-of-laparoscopic-hepatic-bisegmentectomy-with-regional-lymphadenectomy-for-gallbladder-cancer
#9
Hirdaya H Nag, Prithivi Raj, Kshitij Sisodia
BACKGROUND: Laparoscopic hepatic bisegmentectomy (s4b and s5) with regional lymphadenectomy (LHBRL) for patients with gallbladder cancer (GBC) is rarely reported. AIMS: The aim of the study was to describe the technique of LHBRL in patients with GBC and to present our initial experience. PATIENTS AND METHODS: This retrospective study was conducted on twenty patients with GBC who were considered for LHBRL by the described technique. These patients either had a suspicion of GBC (SGBC) or had an incidental diagnosis of GBC (IGBC)...
September 20, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28927868/does-videoendoscopy-provide-three-dimensional-vision-in-closed-rhinoplasty
#10
Guncel Ozturk, Bilge Kagan Aysal
Rhinoplasty is a common procedure in cosmetic surgery all over the world. Patients desire enhancement of their facial beauty by the correction of preexisting nasal deformities. Precisely performed operations lead to better results, and enhancing technical accuracy accordingly results in more successful outcomes. Endoscopy helps us visualize the closed parts of the body with the aid of an illuminated optical device. The objective behind the present case series was to bring the advantages of open and closed rhinoplasty together by using endoscopic vision systems...
August 16, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28927845/cervical-transoral-robotic-oropharyngectomy-and-thin-anterolateral-thigh-free-flap
#11
P Gorphe, S Temam, F Kolb, Q Qassemyar
The transoral robotic oropharyngectomy surgical technique was initially described for resection of small stage T1 or T2 lesions and the surgical defect is usually allowed to heal by secondary intention. We propose a refined surgical approach adapted to more complex situations such as salvage surgery and surgery in an irradiated field, based on previous experience in open approaches for oropharyngeal cancer. Via a combined cervical-transoral approach, we perform en bloc resection of the parapharyngeal space combined with transoral robotic lateral oropharyngectomy...
September 15, 2017: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/28927213/ten-step-minimally-invasive-spine-lumbar-decompression-and-dural-repair-through-tubular-retractors
#12
Mohamed Abdelatif Boukebir, Connor David Berlin, Rodrigo Navarro-Ramirez, Tim Heiland, Karsten Schöller, Cameron Rawanduzy, Sertaç Kirnaz, Ajit Jada, Roger Härtl
BACKGROUND: Minimally invasive spine (MIS) surgery utilizing tubular retractors has become an increasingly popular approach for decompression in the lumbar spine. However, a better understanding of appropriate indications, efficacious surgical techniques, limitations, and complication management is required to effectively teach the procedure and to facilitate the learning curve. OBJECTIVE: To describe our experience and recommendations regarding tubular surgery for lumbar disc herniations, foraminal compression with unilateral radiculopathy, lumbar spinal stenosis, synovial cysts, and dural repair...
April 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28927206/preoperative-magnetic-resonance-and-intraoperative-computed-tomography-fusion-for-real-time-neuronavigation-in-intramedullary-lesion-surgery
#13
Francesco Costa, Alessandro Ortolina, Andrea Cardia, Marco Riva, Martina Revay, Guido Pecchioli, Carla Daniela Anania, Francesco Asteggiano, Maurizio Fornari
BACKGROUND: Image-guided surgery techniques in spinal surgery are usually based upon fluoroscopy or computed tomography (CT) scan, which allow for a real-time navigation of bony structures, though not of neural structures and soft tissue remains. OBJECTIVE: To verify the effectiveness and efficacy of a novel technique of imaging merging between preoperative magnetic resonance imaging (MRI) and intraoperative CT scan during removal of intramedullary lesions. METHODS: Ten consecutive patients were treated for intramedullary lesions using a navigation system aid...
April 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28926644/assessment-of-housing-density-space-allocation-and-social-hierarchy-of-laboratory-rats-on-behavioural-measures-of-welfare
#14
Timothy Hugh Barker, Rebecca Peta George, Gordon Stanley Howarth, Alexandra Louise Whittaker
Minimum space allowances for laboratory rats are legislated based on weight and stocking rates, with the understanding that increased housing density encourages crowding stress. However, there is little evidence for these recommendations, especially when considering positive welfare outcomes. This study consisted of two experiments which investigated the effects of housing density (rats per cage), space allocation (surface area per rat) and social rank (dominance hierarchy) on the ability to perform simple behavioural tests...
2017: PloS One
https://www.readbyqxmd.com/read/28926120/glecaprevir-pibrentasvir-for-hcv-genotype-3-patients-with-cirrhosis-and-or-prior-treatment-experience-a-partially-randomized-phase-iii-clinical-trial
#15
David Wyles, Fred Poordad, Stanley Wang, Laurent Alric, Franco Felizarta, Paul Y Kwo, Benedict Maliakkal, Kosh Agarwal, Tarek Hassanein, Frank Weilert, Samuel S Lee, Jens Kort, Sandra S Lovell, Ran Liu, Chih-Wei Lin, Tami Pilot-Matias, Preethi Krishnan, Federico J Mensa
BACKGROUND: This study assessed the efficacy and safety of ribavirin (RBV)-free coformulated glecaprevir/pibrentasvir (G/P) in patients with hepatitis C virus (HCV) genotype (GT) 3 infection with either prior treatment experience and/or compensated cirrhosis, a patient population with limited treatment options. METHODS: SURVEYOR-II, Part 3 was a partially-randomized, open-label, multicenter, phase 3 study. Treatment-experienced (prior interferon (IFN) or pegIFN ± ribavirin or SOF plus ribavirin ± pegIFN therapy) patients without cirrhosis were randomized 1:1 to receive 12 or 16 weeks of G/P (300 mg/120 mg) once daily...
September 19, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28925997/precision-annotation-of-digital-samples-in-ncbi-s-gene-expression-omnibus
#16
Dexter Hadley, James Pan, Osama El-Sayed, Jihad Aljabban, Imad Aljabban, Tej D Azad, Mohamad O Hadied, Shuaib Raza, Benjamin Abhishek Rayikanti, Bin Chen, Hyojung Paik, Dvir Aran, Jordan Spatz, Daniel Himmelstein, Maryam Panahiazar, Sanchita Bhattacharya, Marina Sirota, Mark A Musen, Atul J Butte
The Gene Expression Omnibus (GEO) contains more than two million digital samples from functional genomics experiments amassed over almost two decades. However, individual sample meta-data remains poorly described by unstructured free text attributes preventing its largescale reanalysis. We introduce the Search Tag Analyze Resource for GEO as a web application (http://STARGEO.org) to curate better annotations of sample phenotypes uniformly across different studies, and to use these sample annotations to define robust genomic signatures of disease pathology by meta-analysis...
September 19, 2017: Scientific Data
https://www.readbyqxmd.com/read/28925799/factors-associated-with-marijuana-use-and-problems-among-college-students-in-colorado
#17
Kristina T Phillips, Michael M Phillips, Kerry D Duck
BACKGROUND: Past studies have shown that heavy marijuana use can impact student outcomes. Frequent use and misuse of marijuana have been associated with a range of psychological and personality factors in young adults, but there has been limited research focused on the college environment in states where marijuana has been legalized for recreational purposes. OBJECTIVES: We examined whether marijuana use and problems were associated with a range of demographic, personality, and psychological variables among college students at a midsized Colorado university...
September 19, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28925265/janus-electrochemistry-asymmetric-functionalization-in-one-step
#18
David Ibañez, Elisa Vallés, Elvira Gómez, Alvaro Colina, Aranzazu Heras
Janus structures represent an overwhelming member of materials with adaptable chemical and physical properties. The development of new synthesis routes has allowed the fabrication of Janus architectures with specific characteristics depending on the final applications. In the case of the membranes, the improvement of wet routes has been limited to the capillary effect, in which the solution can gradually penetrate through the membrane avoiding a double modification, different at each face of the membrane. In this work, we propose a new electrochemical methodology to circumvent the capillary limitation and to obtain a double electrochemical functionalization in only one step in a controlled way...
September 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28924678/gender-opportunities-in-psychosocial-oncology
#19
Matthew Loscalzo, Karen Clark
So much has happened since the original publication of this chapter. In some ways, the progress made in appreciating the full spectrum of sexual and gender expression has been uneven and in some nations, there has been serious regression and resulting repression. But overall, especially in the industrialized countries, there is much greater awareness of sex and gender and its importance in health and well being. In this updated chapter, we put sex and gender into a historical context that is relevant to psycho-oncology and that openly accepts that society overall, is highly conflicted when it comes to how women and men get the best out of each other, never mind how to best integrate lesbian, gay, bisexual, and transgender (LGBT) communities...
2018: Recent Results in Cancer Research
https://www.readbyqxmd.com/read/28924328/grammatical-encoding-and-learning-in-agrammatic-aphasia-evidence-from-structural-priming
#20
Soojin Cho-Reyes, Jennifer E Mack, Cynthia K Thompson
The present study addressed open questions about the nature of sentence production deficits in agrammatic aphasia. In two structural priming experiments, 13 aphasic and 13 age-matched control speakers repeated visually- and auditorily-presented prime sentences, and then used visually-presented word arrays to produce dative sentences. Experiment 1 examined whether agrammatic speakers form structural and thematic representations during sentence production, whereas Experiment 2 tested the lasting effects of structural priming in lags of two and four sentences...
December 2016: Journal of Memory and Language
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