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Surgical oncologist

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https://www.readbyqxmd.com/read/28629583/ex%C3%A2-vivo-retrieval-and-cryopreservation-of-oocytes-from-oophorectomized-specimens-for-fertility-preservation-in-a-brca1-mutation-carrier-with-ovarian-cancer
#1
Nigel Pereira, Andrea G Hubschmann, Jovana P Lekovich, Glenn L Schattman, Zev Rosenwaks
OBJECTIVE: To report a case of ex vivo oocyte retrieval from oophorectomized specimens in a BRCA1 mutation carrier undergoing surgical staging for ovarian cancer. DESIGN: Video case report and literature review. SETTING: University-affiliated center. PATIENT(S): A 37-year-old single woman, gravida 0, with a known BRCA1 mutation, presented to her oncologist with a complex right ovarian mass and elevated CA-125 level...
June 16, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28617687/preoperatively-assessable-clinical-and-pathological-risk-factors-for-parametrial-involvement-in-surgically-treated-figo-stage-ib-iia-cervical-cancer
#2
Emel Canaz, Eser Sefik Ozyurek, Baki Erdem, Merve Aldikactioglu Talmac, Ipek Yildiz Ozaydin, Ozgur Akbayir, Ceyhun Numanoglu, Volkan Ulker
OBJECTIVE: Determining the risk factors associated with parametrial involvement (PMI) is of paramount importance to decrease the multimodality treatment in early-stage cervical cancer. We investigated the preoperatively assessable clinical and pathological risk factors associated with PMI in surgically treated stage IB1-IIA2 cervical cancer. METHODS: A retrospective cohort study of women underwent Querleu-Morrow type C hysterectomy for cervical cancer stage IB1-IIA2 from 2001 to 2015...
June 14, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28616743/the-long-term-survival-of-stage-iv-gastric-cancer-patients-with-conversion-therapy
#3
Kazuya Yamaguchi, Kazuhiro Yoshida, Toshiyuki Tanahashi, Takao Takahashi, Nobuhisa Matsuhashi, Yoshihiro Tanaka, Kazuaki Tanabe, Hideki Ohdan
PURPOSE: A retrospective study was performed to clarify the role of conversion therapy (surgery with a prospect of R0 resection performed in initially unresectable metastatic cancer that responded to the chemotherapy) in stage IV gastric cancer (GC). PATIENTS AND METHODS: We treated 259 stage IV GC patients with systemic chemotherapy at Gifu and Hiroshima University Hospitals between 2001-2013. Of these, 84 patients who were subsequently treated by surgery were classified into four categories according to our previously published classification of stage IV GC, and short- and long-term outcomes were analyzed...
June 14, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28616610/current-approaches-to-gastric-cancer-in-peru-and-mexico
#4
REVIEW
Erlan Santos
In Peru, the incidence of gastric cancer is reported to be around 15.8 per 100,000 inhabitants and it is the second most common oncological disease in men and the third one in women. Additionally, a high mortality index was reported, especially among poor people. To address this issue, in 2008, Peru initiated several insurance treatment plans of oncological diseases with promising results. In Mexico, there is a high predominance of gastric cancer in male gender compared to female gender, even reaching a 2/1 ratio, and the detection rate of early gastric cancer is low (10% to 20%) which results in a mainly palliative treatment with an overall survival rate in 5 years about 10% to 15% only...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28610900/persistence-of-fimbrial-tissue-on-the-ovarian-surface-following-salpingectomy
#5
Carmen Gan, Rashna Chenoy, Dhivya Chandrasekaran, Elly Brockbank, Antony Hollingworth, Sotiris Vimplis, Alexandra C Lawrence, Arjun R Jeyarajah, David Oram, Nandita Deo, Jamna Saravanamuthu, Sarah S Lam, Asma Faruqi, Naveena Singh, Ranjit Manchanda
BACKGROUND: Salpingectomy is recommended as a risk-reducing strategy for epithelial tubo-ovarian cancer. The gold standard procedure is complete tubal excision. OBJECTIVE: To assess the presence of residual fimbrial/tubal tissue on ovarian surfaces following salpingectomy. DESIGN: Prospective analysis of patients undergoing salpingo-oophorectomy +/- hysterectomy for benign indications, early cervical cancer or low risk endometrial cancer at a UK National Health Service Trust...
June 10, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28609357/the-surgical-management-of-small-bowel-neuroendocrine-tumors-consensus-guidelines-of-the-north-american-neuroendocrine-tumor-society
#6
James R Howe, Kenneth Cardona, Douglas L Fraker, Electron Kebebew, Brian R Untch, Yi-Zarn Wang, Calvin H Law, Eric H Liu, Michelle K Kim, Yusuf Menda, Brian G Morse, Emily K Bergsland, Jonathan R Strosberg, Eric K Nakakura, Rodney F Pommier
Small bowel neuroendocrine tumors (SBNETs) have been increasing in frequency over the past decades, and are now the most common type of small bowel tumor. Consequently, general surgeons and surgical oncologists are seeing more patients with SBNETs in their practices than ever before. The management of these patients is often complex, owing to their secretion of hormones, frequent presentation with advanced disease, and difficulties with making the diagnosis of SBNETs. Despite these issues, even patients with advanced disease can have long-term survival...
July 2017: Pancreas
https://www.readbyqxmd.com/read/28608012/the-advent-of-ultra-high-volume-thoracic-surgical-centers-in-shanghai
#7
Alan D L Sihoe, Baohui Han, Timothy Y Yang, Changqing Pan, Gening Jiang, Vincent W T Fang
BACKGROUND: A core principle in surgery is that high surgical volumes are conducive toward better outcomes. Ultra-high volume centers (UHVCs) have now emerged in thoracic surgery in China that now perform a volume of thoracic operations far greater than even traditional international centers of excellence. METHODS: In 2016, two hospitals in Shanghai performed over 10,000 major pulmonary, esophageal and mediastinal resections each. A qualitative analysis of the lessons learned in achieving such large operation volumes was undertaken...
June 12, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28604452/utility-and-actual-use-of-european-and-spanish-guidelines-on-the-management-of-endometrial-cancer-among-gynecologic-oncologists-in-spain
#8
Ignacio Zapardiel, Claudia Blancafort, David Cibula, Ibon Jaunarena, Mikel Gorostidi, Antonio Gil-Moreno, Javier De Santiago
OBJECTIVE: The aim of the study was to analyze the current management of endometrial cancer across Spain and to evaluate the use and applicability of the national and international guidelines. MATERIALS AND METHODS: An electronic 30-question survey was distributed among all Spanish Society of Obstetrics and Gynecology-registered specialists dedicated to gynecologic oncology in Spain by e-mail. Data were collected anonymously and analyzed using SPSS program. RESULTS: One hundred forty-five (17...
June 10, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28594765/patterns-of-specialty-based-referral-and-perioperative-outcomes-for-women-with-endometrial-cancer-undergoing-hysterectomy
#9
Jason D Wright, Ling Chen, Lisa Gabor, William M Burke, Ana I Tergas, June Y Hou, Cande V Ananth, Alfred I Neugut, Dawn L Hershman
OBJECTIVE: To examine patterns of referral to gynecologic oncologists and perioperative outcomes based on surgeon specialty for women with endometrial cancer and hyperplasia. METHODS: The National Surgical Quality Improvement Program database was used to perform a retrospective cohort study of women with endometrial cancer and hyperplasia who underwent hysterectomy from 2014 to 2015. Patients were stratified based on treatment by a gynecologic oncologist or other health care provider...
June 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28594761/wound-complication-rates-after-staples-or-suture-for-midline-vertical-skin-closure-in-obese-women-a-randomized-controlled-trial
#10
Lindsay M Kuroki, Mary M Mullen, L Stewart Massad, Ningying Wu, Jingxia Liu, David G Mutch, Matthew A Powell, Andrea R Hagemann, Premal H Thaker, Carolyn K McCourt, Akiva P Novetsky
OBJECTIVE: To compare wound complication rates after skin closure with staples and subcuticular suture in obese gynecology patients undergoing laparotomy through a midline vertical incision. METHODS: In this randomized controlled trial, women with body mass indexes (BMIs) of 30 or greater undergoing surgery by a gynecologic oncologist through a midline vertical incision were randomized to skin closure with staples or subcuticular 4-0 monofilament suture. The primary outcome was the rate of wound complication, defined as the presence of a wound breakdown, or infection, within 8 weeks postoperatively...
June 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28579359/evolution-in-treatment-strategy-for-metastatic-spine-disease-presently-evolving-modalities
#11
REVIEW
N Kumar, R Malhotra, A S Zaw, K Maharajan, N Naresh, A Kumar, B Vellayappan
The advent of minimally invasive surgery (MIS) in the surgical management armamentarium and stereotactic radiosurgery in the domain of radiotherapy, has led to a major evolution in treatment of metastatic spine disease (MSD). We reviewed the recent literature to discuss evolution from open to MIS approaches in MSD and the concurrent evolution in radiotherapy. This will provide a sound base for further development and understanding of treatment paradigms in MSD. Literature review showed that evolution of surgery can be traced from inappropriate open surgery (i...
May 17, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28576180/optimal-use-of-combined-modality-therapy-in-the-treatment-of-esophageal-cancer
#12
REVIEW
Talha Shaikh, Joshua E Meyer, Eric M Horwitz
Esophageal cancer is associated with a poor prognosis with 5-year survival rates of approximately 15% to 20%. Although patients with early stage disease may adequately be treated with a single modality, combined therapy typically consisting of neoadjuvant chemoradiation followed by esophagectomy is being adopted increasingly in patients with locally advanced disease. In patients who are not surgical candidates, definitive chemoradiation is the preferred treatment approach. All patients with newly diagnosed esophageal cancer should be evaluated in the multidisciplinary setting by a surgeon, radiation oncologist, and medical oncologist owing to the importance of each specialty in the management of these patients...
July 2017: Surgical Oncology Clinics of North America
https://www.readbyqxmd.com/read/28567071/associating-liver-partition-and-portal-vein-ligation-for-staged-hepatectomy-a-surgical-technique-for-liver-resections
#13
Behnam Sanei, Saba Sheikhbahaei, Mohammad Hossein Sanei, Amin Bahreini, Hamid Reza Jafari
BACKGROUND: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel surgical technique liver resection in traditionally nonresectable primary intrahepatic tumors or colorectal liver metastases. MATERIALS AND METHODS: From June 2013 to March 2014, patients with primary tumor of liver or colorectal tumors with liver metastasis were selected to evaluate whether they met the initial criteria for ALPPS procedure. RESULTS: Nine patients enrolled in the study with primary diagnoses of colon and rectosigmoid cancer, carcinoid tumor, gastrointestinal stromal tumor of small intestine, hepatocellular carcinoma, and pancreatic neuroendocrine tumor (PNET)...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28561681/cancer-care-and-control-as-a-human-right-recognizing-global-oncology-as-an-academic-field
#14
Alexandru E Eniu, Yehoda M Martei, Edward L Trimble, Lawrence N Shulman
The global burden of cancer incidence and mortality is on the rise. There are major differences in cancer fatality rates due to profound disparities in the burden and resource allocation for cancer care and control in developed compared with developing countries. The right to cancer care and control should be a human right accessible to all patients with cancer, regardless of geographic or economic region, to avoid unnecessary deaths and suffering from cancer. National cancer planning should include an integrated approach that incorporates a continuum of education, prevention, cancer diagnostics, treatment, survivorship, and palliative care...
2017: American Society of Clinical Oncology Educational Book
https://www.readbyqxmd.com/read/28528268/optimistic-honesty-understanding-surgeon-and-patient-perspectives-on-hopeful-communication-in-pancreatic-cancer-care
#15
Kim Blakely, Paul J Karanicolas, Frances C Wright, Lesley Gotlib Conn
BACKGROUND: Prognosis conversations between surgical oncologists and patients with pancreatic cancer are critically important and challenging. Surgeons and their patients often have discrepant understandings of prognosis despite extensive conversations. Little is known about how surgeons approach prognosis conversations with these patients; patients' experiences with these conversations are also not well understood. This qualitative study sought to better understand surgeon and patient perspectives on communication in pancreatic cancer care with a view toward improvement...
May 17, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28526721/health-care-resource-utilization-and-associated-costs-among-metastatic-cutaneous-melanoma-patients-treated-with-ipilimumab-intuition-study
#16
Grant A McArthur, Peter Mohr, Paolo Antonio Ascierto, Ana Arance, Ana Banos Hernaez, Peter Kaskel, Michael Weichenthal, Reshma Shinde, Kendall Stevinson
BACKGROUND: There are limited real-world data on health care resource utilization (HCRU) among advanced melanoma patients. The objective of this study was to describe HCRU and health care costs associated with the management of advanced melanoma patients receiving ipilimumab. METHODS: This retrospective multinational, observational study included advanced melanoma patients from Australia, Germany, Italy, and Spain who had received at least 1 dose of ipilimumab. Data extracted from medical charts included inpatient admissions, outpatient visits, surgical procedures, laboratory investigations, radiation therapy, imaging studies, and concomitant medications...
May 19, 2017: Oncologist
https://www.readbyqxmd.com/read/28507888/spine-stereotactic-body-radiotherapy-indications-outcomes-and-points-of-caution
#17
Chia-Lin Tseng, Wietse Eppinga, Raphaele Charest-Morin, Hany Soliman, Sten Myrehaug, Pejman Jabehdar Maralani, Mikki Campbell, Young K Lee, Charles Fisher, Michael G Fehlings, Eric L Chang, Simon S Lo, Arjun Sahgal
STUDY DESIGN: A broad narrative review. OBJECTIVES: The objective of this article is to provide a technical review of spine stereotactic body radiotherapy (SBRT) planning and delivery, indications for treatment, outcomes, complications, and the challenges of response assessment. The surgical approach to spinal metastases is discussed with an overview of emerging minimally invasive techniques. METHODS: A comprehensive review of the literature was conducted on the techniques, outcomes, and developments in SBRT and surgery for spinal metastases...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28507844/an-innovative-risk-reducing-approach-to-postmastectomy-radiation-delivery-after-autologous-breast-reconstruction
#18
Merisa L Piper, Maristella Evangelista, Dominic Amara, David Daar, Robert D Foster, Barbara Fowble, Hani Sbitany
INTRODUCTION: Postmastectomy radiation therapy (PMRT) has known deleterious side effects in immediate autologous breast reconstruction. However, plastic surgeons are rarely involved in PMRT planning. Our institution has adopted a custom bolus approach for all patients receiving PMRT. This offers uniform distribution of standard radiation doses, thereby minimizing radiation-induced changes while maintaining oncologic safety. We present our 8-year experience with the custom bolus approach for PMRT delivery in immediate autologous breast reconstruction...
April 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28495808/comprehensive-genomic-profiling-of-esthesioneuroblastoma-reveals-additional-treatment-options
#19
Laurie M Gay, Sungeun Kim, Kyle Fedorchak, Madappa Kundranda, Yazmin Odia, Chaitali Nangia, James Battiste, Gerardo Colon-Otero, Steven Powell, Jeffery Russell, Julia A Elvin, Jo-Anne Vergilio, James Suh, Siraj M Ali, Philip J Stephens, Vincent A Miller, Jeffrey S Ross
BACKGROUND: Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare malignant neoplasm of the olfactory mucosa. Despite surgical resection combined with radiotherapy and adjuvant chemotherapy, ENB often relapses with rapid progression. Current multimodality, nontargeted therapy for relapsed ENB is of limited clinical benefit. MATERIALS AND METHODS: We queried whether comprehensive genomic profiling (CGP) of relapsed or refractory ENB can uncover genomic alterations (GA) that could identify potential targeted therapies for these patients...
May 11, 2017: Oncologist
https://www.readbyqxmd.com/read/28495690/intensive-care-in-thoracic-oncology
#20
Anne-Pascale Meert, Bogdan Grigoriu, Marc Licker, Paul E Van Schil, Thierry Berghmans
The admission of lung cancer patients to intensive care is related to postprocedural/postoperative care and medical complications due to cancer or its treatment, but is also related to acute organ failure not directly related to cancer.Despite careful preoperative risk management and the use of modern surgical and anaesthetic techniques, thoracic surgery remains associated with high morbidity, related to the extent of resection and specific comorbidities. Fast-tracking processes with timely recognition and treatment of complications favourably influence patient outcome...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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