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https://www.readbyqxmd.com/read/27898747/-review-of-medical-or-combined-treatment-of-local-or-locally-advanced-oesophageal-cancer
#1
Tünde Nagy, Gábor Rubovszky
More than 800 oesophageal tumours are diagnosed each year in Hungary. The disease is characterized by high mortality. The curative treatment traditionally surgical, although the study results of recent decades pointed out that patient outcome can be improved with the proper application of radio- and chemotherapy. The diverse study designs, the low number of recruited patients and the sometimes conflicting results make the determination of optimal treatment difficult. The aim of this work is to facilitate the choice of treatment modality with the best outcome, especially with the view of medical oncologists...
November 29, 2016: Magyar Onkologia
https://www.readbyqxmd.com/read/27898067/the-need-for-multidisciplinarity-in-specialist-training-to-optimize-future-patient-care
#2
REVIEW
Alison C Tree, Victoria Harding, Aneel Bhangu, Venkatesh Krishnasamy, Dion Morton, Justin Stebbing, Bradford J Wood, Ricky A Sharma
Harmonious interactions between radiation, medical, interventional and surgical oncologists, as well as other members of multidisciplinary teams, are essential for the optimization of patient care in oncology. This multidisciplinary approach is particularly important in the current landscape, in which standard-of-care approaches to cancer treatment are evolving towards highly targeted treatments, precise image guidance and personalized cancer therapy. Herein, we highlight the importance of multidisciplinarity and interdisciplinarity at all levels of clinical oncology training...
November 29, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27875188/pelvis-atlas-based-surgical-planning-for-oncological-pelvic-surgery
#3
Noeska Smit, Kai Lawonn, Annelot Kraima, Marco DeRuiter, Hessam Sokooti, Stefan Bruckner, Elmar Eisemann, Anna Vilanova
Due to the intricate relationship between the pelvic organs and vital structures, such as vessels and nerves, pelvic anatomy is often considered to be complex to comprehend. In oncological pelvic surgery, a trade-off has to be made between complete tumor resection and preserving function by preventing damage to the nerves. Damage to the autonomic nerves causes undesirable post-operative side-effects such as fecal and urinal incontinence, as well as sexual dysfunction in up to 80 percent of the cases. Since these autonomic nerves are not visible in pre-operative MRI scans or during surgery, avoiding nerve damage during such a surgical procedure becomes challenging...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27873183/interdisciplinary-oncology-education-a-national-survey-of-trainees-and-program-directors-in-the-united-states
#4
Adil S Akthar, Christopher D Hellekson, Sabha Ganai, Olwen M Hahn, Ronald J Maggiore, Ezra E Cohen, Mitchell C Posner, Steven J Chmura, Andrew R Howard, Daniel W Golden
Oncologists must have a strong understanding of collaborating specialties in order to deliver optimal cancer care. The objective of this study was to quantify current interdisciplinary oncology education among oncology training programs across the USA, identify effective teaching modalities, and assess communication skills training. Web-based surveys were sent to oncology trainees and program directors (PDs) across the USA on April 1, 2013 and October 8, 2013, respectively. Question responses were Yes/No, five-point Likert scales (1 = not at all, 2 = somewhat, 3 = moderately, 4 = quite, 5 = extremely), or free response...
November 21, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/27872987/the-ir-evolution-in-oncology-tools-treatments-and-guidelines
#5
Thierry de Baere
Early focus of interventional oncologists was developing tools and imaging guidance, performing "procedures" acting as a skillful technician without knowledge of clinical patient outcomes, beyond post-treatment image findings. Interventional oncologists must deliver "treatments" and not "procedures", and focus on clinically relevant outcomes, provide clinical continuity of care, which means stand at multidisciplinary tumor boards, see patients in consultation before treatment and for follow-up. Interventional oncologists have fought for the same "market" with surgery in a head to head, bloody competition called red ocean strategy in marketing terms, resulting in many aborted trials...
November 21, 2016: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/27861907/factors-predictive-of-failure-to-complete-planned-intraoperative-breast-radiation-using-the-intrabeam%C3%A2-system
#6
Lesly A Dossett, Andrea M Abbott, Weihong Sun, Loretta Loftus, Marie Catherine Lee, Roberto Diaz, Christine Laronga
PURPOSE: Intraoperative radiation therapy (IORT) is a form of breast irradiation that is delivered in a single session at the time of partial mastectomy. In up to 10% of patients, planned IORT is not completed; this leads to wasted resources and decreased patient satisfaction. Our objective was to evaluate factors associated with failure to complete planned IORT. METHODS AND MATERIALS: An IRB-approved review of planned IORT cases from 2011 to 2015 was conducted...
November 11, 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27847400/simplified-prosthetic-rehabilitation-of-a-patient-after-oral-cancer-removal
#7
Josip Kranjčić, Nikola Džakula, Denis Vojvodić
The treatment of patients with oral cancer is complex: a multidisciplinary approach needs to be taken and maxillofacial and oral surgeons, an oncologist, a prosthodontist should be included, and a psychologist is often needed. This case report describes the prosthetic rehabilitation of a patient after surgical removal of oral cancer with obturator prosthesis. Resection cavity was located in central part of the hard palate and the condition belonged to Aramany class 3 maxillary defects. The two-step impression technique of denture bearing area was used and the resection of cavity was performed...
September 2016: Acta Stomatologica Croatica
https://www.readbyqxmd.com/read/27836205/effectiveness-of-cyanoacrylate-microbial-sealant-in-the-reduction-of-surgical-site-infection-in-gynecologic-oncology-procedures-a-phase-iii-single-institution-prospective-randomized-trial
#8
Eric D Thomas, Elizabeth K Nugent, Matthew C MacAllister, Katherine M Moxley, Lisa Landrum, Joan L Walker, D S McMeekin, Robert S Mannel, Gerald McGwin, Kathleen N Moore
OBJECTIVES: Surgery is a cornerstone for patients with gynecologic malignancies. Surgical site infections (SSI) remain a source of post-operative morbidity. Consequences range from escalated costs, delay in adjuvant therapy, and increased morbidity. Our primary objective was to evaluate the effectiveness of a cyanoacrylate microbial sealant (CMS) to reduce post-operative SSI following laparotomy for suspected gynecologic malignancy. METHODS: Patients were randomized using a 1:1 allocation to receive either standard skin preparation or standard preparation with CMS and stratified by BMI...
November 8, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27834628/consensus-guidelines-for-postoperative-stereotactic-body-radiation-therapy-for-spinal-metastases-results-of-an-international-survey
#9
Kristin J Redmond, Simon S Lo, Scott G Soltys, Yoshiya Yamada, Igor J Barani, Paul D Brown, Eric L Chang, Peter C Gerszten, Samuel T Chao, Robert J Amdur, Antonio A F De Salles, Matthias Guckenberger, Bin S Teh, Jason Sheehan, Charles R Kersh, Michael G Fehlings, Moon-Jun Sohn, Ung-Kyu Chang, Samuel Ryu, Iris C Gibbs, Arjun Sahgal
OBJECTIVE Although postoperative stereotactic body radiation therapy (SBRT) for spinal metastases is increasingly performed, few guidelines exist for this application. The purpose of this study is to develop consensus guidelines to promote safe and effective treatment for patients with spinal metastases. METHODS Fifteen radiation oncologists and 5 neurosurgeons, representing 19 centers in 4 countries and having a collective experience of more than 1300 postoperative spine SBRT cases, completed a 19-question survey about postoperative spine SBRT practice...
November 11, 2016: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/27826480/aesthetic-surgery-in-patients-with-lung-cancer-a-paradigm-shift
#10
David A Hidalgo, Jan Baranski, Sammy Sinno
BACKGROUND: Lung cancer is the most common cancer worldwide and the leading cause of cancer death. With the development of targeted therapy against causative driver mutations, some patients have experienced dramatic responses that have converted their disease into a chronic, stable form. Shifting concerns away from survival and back to quality-of-life issues has led some of these patients to seek aesthetic surgery. METHODS: Three patient examples are presented to illustrate current lung cancer treatment modalities, disease responses, and subsequent experiences with aesthetic surgical procedures...
October 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27815041/feasibility-of-robotic-assisted-laparoendoscopic-single-site-surgery-in-the-gynecologic-oncology-setting
#11
Lea A Moukarzel, Amanda N Fader, Edward J Tanner
STUDY OBJECTIVE: To assess the feasibility of incorporating robotic laparoendoscopic single-site (R-LESS) surgery into gynecologic oncology care. DESIGN: Retrospective study (Canadian Task Force classification II-3). SETTING: Academic university hospital. PATIENTS: Patients undergoing R-LESS hysterectomy for gynecologic malignancies, preinvasive disease, or risk reduction performed by a single gynecologic oncologist between 2014 and 2016...
November 1, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27797838/systemic-sarcoidosis-first-manifesting-in-a-tattoo-in-the-setting-of-immune-checkpoint-inhibition
#12
Charissa Kim, Jianjun Gao, Vickie R Shannon, Arlene Siefker-Radtke
The use of immune checkpoint inhibitors is revolutionising the treatment of cancer. However, their unique toxicity profile is substantially different from what has been observed with traditional chemotherapy, resulting in a novel learning curve for medical oncologists. Early recognition of these toxicities can make a substantial impact in ameliorating these side effects in the oncological and medical-surgical fields. Here, we present a case of Lofgren syndrome sarcoidosis, which first manifested in a tattoo in a patient with metastatic urothelial cancer on therapy with anti-CTLA-4 (ipilimumab) and anti-PD1 (nivolumab)...
October 26, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27779352/prioritizing-patient-reported-outcomes-in-breast-cancer-surgery-quality-improvement
#13
Sara H Javid, Sarah O Lawrence, Danielle C Lavallee
Breast-cancer-specific tools that measure health-related quality of life (HRQOL) were developed for use in research or clinical practice, and little is known about these tools' performance ability for quality improvement. Furthermore, existing tools may not fully reflect all issues that contribute to quality care as seen by patients. Work is needed to identify and validate patient-reported outcome measures for use in quality improvement in breast cancer surgical care. We conducted an exploratory qualitative study in order to better understand what HRQOL domains and processes of care define high quality surgical care for women undergoing mastectomy for breast cancer from both the patient and clinician perspective...
October 25, 2016: Breast Journal
https://www.readbyqxmd.com/read/27753056/prevention-and-screening-in-hereditary-breast-and-ovarian-cancer
#14
Simon B Zeichner, Christine Stanislaw, Jane L Meisel
In recent years, we have learned a great deal about pathogenic mutations that increase the risk of breast and ovarian cancer, particularly mutations in the BRCA1 and BRCA2 genes. Here we review current guidelines on breast and ovarian cancer screening, prophylactic surgery, and other risk-reduction strategies in patients with these mutations, and we detail the data that drive these recommendations. We also discuss guidelines on screening and management for other cancers associated with BRCA1 and BRCA2, such as male breast cancer, pancreatic cancer, and prostate cancer...
October 15, 2016: Oncology (Williston Park, NY)
https://www.readbyqxmd.com/read/27742118/pediatric-cerebellar-tumors-emerging-imaging-techniques-and-advances-in-understanding-of-genetic-features
#15
Asim F Choudhri, Adeel Siddiqui, Paul Klimo
Cerebellar tumors are the most common group of solid tumors in children. MR imaging provides an important role in characterization of these lesions, surgical planning, and postsurgical surveillance. Preoperative imaging can help predict the histologic subtype of tumors, which can provide guidance for surgical planning. Beyond histology, pediatric brain tumors are undergoing new classification schemes based on genetic features. Intraoperative MR imaging has emerged as an important tool in the surgical management of pediatric brain tumors...
November 2016: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/27709403/variation-in-the-types-of-providers-participating-in-breast-cancer-follow-up-care-a-seer-medicare-analysis
#16
Heather B Neuman, Jessica R Schumacher, David F Schneider, Emily R Winslow, Rebecca A Busch, Jennifer L Tucholka, Maureen A Smith, Caprice C Greenberg
BACKGROUND: The current guidelines do not delineate the types of providers that should participate in early breast cancer follow-up care (within 3 years after completion of treatment). This study aimed to describe the types of providers participating in early follow-up care of older breast cancer survivors and to identify factors associated with receipt of follow-up care from different types of providers. METHODS: Stages 1-3 breast cancer survivors treated from 2000 to 2007 were identified in the Surveillance, Epidemiology and End results Medicare database (n = 44,306)...
October 5, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27686592/boost-delineation-in-breast-radiation-therapy-isotropic-versus-anisotropic-margin-expansion
#17
Karolien Verhoeven, Stéphanie Peeters, Katrien Erven, Hilde Janssen, Isabelle Kindts, Erik Van Limbergen, Annouschka Laenen, Saskia Petillion, Caroline Weltens
PURPOSE: The purpose of this article is to compare isotropic and anisotropic margin expansion with regard to the size of the clinical target volume boost (CTVboost) and the interobserver variability (IOV). METHODS AND MATERIALS: Lumpectomy cavities marked with 3 or more surgical clips were delineated by 6 radiation oncologists who specialized in breast radiation therapy. CTVboost anisotropic was created by manually expanding the tumor bed with an anisotropic margin of 15 mm (20 mm in case of extensive intraductal component) minus the surgical free margins in 6 directions (anteroposterior, craniocaudal, and superoinferior)...
March 19, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/27643653/hypomagnesemia-is-prevalent-in-patients-undergoing-gynecologic-surgery-by-a-gynecologic-oncologist
#18
Michael A Ulm, Catherine H Watson, Prethi Vaddadi, Jim Y Wan, Joseph T Santoso
OBJECTIVE: The aim of this study was to assess the incidence of and risk factors for hypomagnesemia in patients undergoing gynecologic surgery by a gynecologic oncologist. METHODS: A retrospective chart review was performed on all patients undergoing surgery for gynecologic pathology from July 2011 to July 2015 by a single surgeon. Demographic data, surgical indication, surgery performed, preoperative laboratory values, postoperative laboratory values, and medical history were examined...
September 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27642084/quality-assessment-of-lymph-node-sampling-in-rhabdomyosarcoma-a-surveillance-epidemiology-and-end-results-seer-program-study
#19
Inna Lobeck, Phylicia Dupree, Rebekah Karns, David Rodeberg, Daniel von Allmen, Roshni Dasgupta
BACKGROUND: Lymph node sampling is integral in the management of extremity and paratesticular rhabdomyosarcoma (RMS). The aim of this study was to determine overall surgical compliance with treatment protocols and impact of nodal sampling outcomes in these tumors. METHODS: A query of the surveillance, epidemiology, and end results program (SEER) database was performed from 2003 to 2008 for patients <19years of age with RMS. Data obtained included demographics, five-year survival and rate of nodal sampling...
September 2, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27640196/patterns-of-multidisciplinary-care-in-the-management-of-non-metastatic-invasive-breast-cancer-in-the-united-states-medicare-patient
#20
Thomas M Churilla, Brian L Egleston, Colin T Murphy, Elin R Sigurdson, Shelly B Hayes, Lori J Goldstein, Richard J Bleicher
PURPOSE: Multidisciplinary care (MDC) in managing breast cancer is resource-intensive and growing in prevalence anecdotally, although care patterns are poorly characterized. We sought to determine MDC patterns and effects on care in the United States Medicare patient. METHODS: Patients diagnosed with non-metastatic invasive breast cancer from 1992-2009 were reviewed using the Survival, Epidemiology, and End Results (SEER)-Medicare linked dataset. MDC was defined as a post-diagnosis, preoperative visit with a surgical, medical, and radiation oncologist...
November 2016: Breast Cancer Research and Treatment
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