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pci in stable angina

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https://www.readbyqxmd.com/read/28100874/efficacy-of-multidetector-computed-tomography-to-predict-periprocedural-myocardial-injury-after-percutaneous-coronary-intervention-for-chronic-total-occlusion
#1
Eisuke Usui, Tetsumin Lee, Tadashi Murai, Yoshihisa Kanaji, Junji Matsuda, Makoto Araki, Taishi Yonetsu, Yosuke Yamakami, Shigeki Kimura, Tsunekazu Kakuta
Specific signatures of culprit lesions detected on multidetector computed tomography (MDCT) were identified as predictors of periprocedural myocardial injury (PMI) after percutaneous coronary intervention (PCI) in patients with stable angina; PMI has been shown to be associated with a worse prognosis. We investigated the association between preprocedural culprit lesion characteristics, assessed by MDCT, and PMI after PCI for chronic total occlusion (CTO). From three medical centers, 81 patients who underwent pre-PCI MDCT and CTO PCI, and systematic cardiac troponin (cTn) sampling before and after PCI, were included...
January 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28092977/hypertension-is-associated-with-increased-mortality-in-patients-with-ischaemic-heart-disease-after-revascularization-with-percutaneous-coronary-intervention-a-report-from-scaar
#2
Ott Saluveer, Björn Redfors, Oskar Angerås, Christian Dworeck, Inger Haraldsson, Charlotta Ljungman, Petur Petursson, Jacob Odenstedt, Dan Ioanes, Peter Lundgren, Sebastian Völz, Truls Råmunddal, Bert Andersson, Elmir Omerovic, Niklas Bergh
BACKGROUND: The prognostic role of hypertension on long-term survival after percutaneous coronary intervention (PCI) is limited and inconsistent. We hypothesize that hypertension increases long-term mortality after PCI. METHODS: We analyzed data from SCAAR (Swedish Coronary Angiography and Angioplasty Registry) for all consecutive patients admitted coronary care units in Sweden between January 1995 and May 2013 and who underwent PCI due to ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI)/unstable angina (UA) or stable angina pectoris...
January 16, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28076449/long-term-follow-up-of-patients-after-percutaneous-coronary-intervention-with-everolimus-eluting-bioresorbable-vascular-scaffold
#3
Rafael Alexandre Meneguz-Moreno, José de Ribamar Costa, Freddy Antônio Britto Moscoso, Rodolfo Staico, Luiz Fernando Leite Tanajura, Marinella Patrizia Centemero, Auréa Jacob Chaves, Andrea Claudia Leão de Sousa Abizaid, Amanda Guerra de Moraes Rego E Sousa, Alexandre Antonio Cunha Abizaid
Background: Bioresorbable vascular scaffolds (BVS) were developed to improve the long-term results of percutaneous coronary intervention, restoring vasomotion. Objectives: To report very late follow-up of everolimus-eluting Absorb BVS (Abbott Vascular, Santa Clara, USA) in our center. Methods: Observational retrospective study, in a single Brazilian center, from August 2011 to October 2013, including 49 patients submitted to Absorb BVS implantation...
January 9, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28042404/in-hospital-and-one-year-clinical-outcome-of-percutaneous-coronary-intervention-in-a-tertiary-hospital-in-oman-oman-pci-registry
#4
Prashanth Panduranga, Majdah Al-Rashidi, Fatma Al-Hajri
OBJECTIVES: The aim of the study was to investigate the in-hospital and one-year clinical outcome of patients treated with percutaneous coronary intervention (PCI) in a tertiary hospital in Oman. METHODS: We conducted a retrospective, single-center, observational study looking at patients > 18 years old who underwent a PCI from 1 January to 31 December 2013. The primary end point was the occurrence of a major adverse cardiovascular event (MACE), defined as death, any myocardial infarction (MI), cerebrovascular accident (CVA), and target vessel revascularization (TVR) with either repeat PCI or coronary artery bypass surgery (CABG)...
January 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28034517/impact-of-paradoxical-decrease-in-high-density-lipoprotein-cholesterol-levels-after-statin-therapy-on-major-adverse-cardiovascular-events-in-patients-with-stable-angina-pectoris
#5
Kenshi Hirayama, Tomoyuki Ota, Kazuhiro Harada, Yohei Shibata, Yosuke Tatami, Shingo Harata, Kazuhiro Kawashima, Ayako Kunimura, Yusaku Shimbo, Yohei Takayama, Toshiki Kawamiya, Dai Yamamoto, Naohiro Osugi, Susumu Suzuki, Hideki Ishii, Toyoaki Murohara
PURPOSE: Statin therapy usually increases HDL-C levels. However, a paradoxical decrease in HDL-C levels after statin therapy is often seen in clinical settings. The relationship between a paradoxical decrease in HDL-C levels after statin therapy and adverse cardiovascular events in patients with stable angina pectoris (SAP) is not well understood. The purpose of this study was to analyze the relationship between paradoxical HDL-C decreases after statin therapy and major adverse cardiovascular events (MACEs) in patients undergoing percutaneous coronary intervention (PCI) for SAP...
December 26, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/28031149/diagnostic-and-prognostic-value-of-a-careful-symptom-evaluation-and-high-sensitive-troponin-in-patients-with-suspected-stable-angina-pectoris-without-prior-cardiovascular-disease
#6
Debbie M Madsen, Axel C P Diederichsen, Susanne E Hosbond, Oke Gerke, Hans Mickley
BACKGROUND AND AIMS: Typical angina pectoris (AP) and high-sensitive troponin I (hs-TnI) are independently associated with coronary artery disease (CAD) and future cardiovascular events (CVE). This study aimed to assess the individual and combined diagnostic and prognostic impact of symptoms and hs-TnI in stable chest pain patients without prior cardiovascular disease. METHODS: During a one-year period, 487 patients with suspected stable AP underwent invasive or CT-coronary angiography (significant stenosis ≥50%)...
November 28, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/28017291/rationale-design-and-goals-of-the-heartflow-assessing-diagnostic-value-of-non-invasive-ffrct-in-coronary-care-advance-registry
#7
Kavitha M Chinnaiyan, Takashi Akasaka, Tetsuya Amano, Jeroen J Bax, Philipp Blanke, Bernard De Bruyne, Tomohiro Kawasaki, Jonathon Leipsic, Hitoshi Matsuo, Yoshihiro Morino, Koen Nieman, Bjarne L Norgaard, Manesh R Patel, Gianluca Pontone, Mark Rabbat, Campbell Rogers, Neils Peter Sand, Gilbert Raff
BACKGROUND: Coronary CT angiography (CTA) is a reliable tool for the detection of coronary artery disease (CAD) that conveys significant prognostic information. It does not provide data on the hemodynamic significance of a given lesion, particularly in intermediate-grade stenosis. Fractional flow reserve by CT (FFRCT) can accurately predict the hemodynamic significance of coronary lesions. The primary objective of this registry is to determine whether the integration of FFRCT as an adjunct to coronary CTA will lead to a significant change in the management of CAD in patients with stable angina...
December 14, 2016: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28005559/the-impact-of-blood-pressure-variability-on-coronary-plaque-vulnerability-in-stable-angina-an-analysis-using-optical-coherence-tomography
#8
Rie Aoyama, Hitoshi Takano, Keishi Suzuki, Yoshiaki Kubota, Keisuke Inui, Yukichi Tokita, Wataru Shimizu
BACKGROUND: Blood pressure variability (BPV), especially visit-to-visit BPV, has been reported to be a risk factor for cardiovascular disease. The impact of BPV on coronary plaque vulnerability remains uncertain. The aim of this study was to investigate the relationship between BPV and coronary plaque vulnerability. PATIENTS AND METHODS: From August 2013 to May 2014, 36 patients with both hypertension and stable angina pectoris who underwent a percutaneous coronary intervention guided by frequency-domain optical coherence tomography were investigated retrospectively...
December 21, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/27998900/randomised-double-blind-placebo-controlled-study-investigating-the-effects-of-inorganic-nitrate-on-vascular-function-platelet-reactivity-and-restenosis-in-stable-angina-protocol-of-the-nitrate-oct-study
#9
Krishnaraj S Rathod, Daniel A Jones, T J A Van-Eijl, Hilda Tsang, Helen Warren, Stephen M Hamshere, Vikas Kapil, Ajay K Jain, Andrew Deaner, Neil Poulter, Mark J Caulfield, Anthony Mathur, Amrita Ahluwalia
INTRODUCTION: The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery. While this procedure has revolutionised treatment, the incidence of secondary events remains a concern. These repeat events are thought to be due, in part, to continued enhanced platelet reactivity, endothelial dysfunction and ultimately restenosis of the stented artery. In this study, we will investigate whether a once a day inorganic nitrate administration might favourably modulate platelet reactivity and endothelial function leading to a decrease in restenosis...
December 20, 2016: BMJ Open
https://www.readbyqxmd.com/read/27973330/three-dimensional-volumetric-assessment-of-coronary-artery-calcification-in-patients-with-stable-coronary-artery-disease-by-oct
#10
Parasuram Krishnamoorthy, Yuliya Vengrenyuk, Hiroshi Ueda, Takahiro Yoshimura, Jacobo Pena, Sadako Motoyama, Usman Baber, Choudhury Hasan, Srinivas Kesanakurthy, Joseph M Sweeny, Samin K Sharma, Jagat Narula, Jason C Kovacic, Annapoorna S Kini
AIMS: There is a lack of reliable technique to quantify coronary artery calcification (CAC). Hence, we used Optical Coherence Tomography (OCT) to quantitate 3- dimensional CAC volume to examine its association with plaque characteristics. METHODS AND RESULTS: A total of 250 patients with stable angina undergoing OCT imaging before PCI were included. CAC volume was calculated from every frame of the culprit lesion and divided into tertiles (low, intermediate and high)...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27969855/tct-496-differences-in-quantitative-coronary-angiographic-qca-characteristics-of-coronary-artery-disease-between-human-immunodeficiency-virus-hiv-patients-presenting-with-acute-coronary-syndrome-acs-and-stable-angina-pectoris-sap-undergoing-percutaneous-coronary
#11
Kleanthis Theodoropoulos, Omar Meelu, Marco Mennuni, Samantha Sartori, Jennifer Yu, Usman Baber, Giulio Stefanini, Ioannis Mastoris, Pedro Moreno, George Dangas, Roxana Mehran, Samin Sharma, Annapoorna Kini
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27914491/impact-of-lesion-characteristics-on-the-prediction-of-optimal-poststent-fractional-flow-reserve
#12
Hirohiko Ando, Hiroaki Takashima, Akihiro Suzuki, Shinichiro Sakurai, Soichiro Kumagai, Akiyoshi Kurita, Katsuhisa Waseda, Tetsuya Amano
BACKGROUND: Poststent fractional flow reserve (FFR) is a useful indicator of optimal percutaneous coronary intervention, and higher poststent FFR is associated with favorable long-term clinical outcome. However, little is known about the factors influencing poststent FFR. The purpose of this study was to determine the impact of lesion characteristics on poststent FFR. METHODS: For patients who had scheduled stent implantation for stable angina, FFR measurements at maximum hyperemia were performed before and after coronary stent implantation...
December 2016: American Heart Journal
https://www.readbyqxmd.com/read/27913753/neutrophil-derived-microparticles-are-released-into-the-coronary-circulation-following-percutaneous-coronary-intervention-in-acute-coronary-syndrome-patients
#13
Gonzalo J Martínez, Jennifer Y Barraclough, Shirley Nakhla, Vivian Kienzle, Stacy Robertson, Ziad Mallat, David S Celermajer, Sanjay Patel
To evaluate (i) local coronary and systemic levels of microparticles (MP) in acute coronary syndrome (ACS) and stable angina pectoris (SAP) patients and (ii) their release after plaque disruption with percutaneous coronary intervention (PCI). MP are small vesicles originating from plasma membranes of cells after activation or apoptosis and are implicated in the pathogenesis of atherosclerosis. Neutrophils play a role in plaque destabilization and shed neutrophil-derived MP that have the potential to drive significant proinflammatory and thrombotic downstream effects...
February 28, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/27912733/the-effect-of-percutaneous-coronary-intervention-on-habitual-physical-activity-in-older-patients
#14
Sarah J Charman, Vincent T van Hees, Louise Quinn, Joseph R Dunford, Bilal Bawamia, Murugapathy Veerasamy, Michael I Trenell, Djordje G Jakovljevic, Vijay Kunadian
BACKGROUND: Given the ongoing burden of cardiovascular disease and an ageing population, physical activity in patients with coronary artery disease needs to be emphasized. This study assessed whether sedentary behaviour and physical activity levels differed among older patients (≥75 years) following percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) consisting of ST-segment elevation myocardial infarction (STEMI) and non STEMI (NSTEMI) versus an elective admission control group of stable angina patients...
December 3, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27900989/negative-association-of-circulating-microrna-126-with-high-sensitive-c-reactive-protein-and-vascular-cell-adhesion-molecule-1-in-patients-with-coronary-artery-disease-following-percutaneous-coronary-intervention
#15
Jun-Nan Wang, You-You Yan, Zi-Yuan Guo, Ya-Juan Jiang, Lu-Lu Liu, Bin Liu
BACKGROUND: Percutaneous coronary intervention (PCI) causes endothelial damage, resulting in an inflammatory response with elevation of markers such as high-sensitive C-reactive protein (hs-CRP) and vascular cell adhesion molecule-1 (VCAM-1), which are associated with restenosis after PCI. Evidence suggests that microRNA-126 (miR-126) plays an important role in vascular inflammation, but its correlation with PCI-mediated inflammation has not been investigated. In this study, we investigated the effect of PCI on circulating miR-126 and inflammation markers such as hs-CRP and VCAM-1...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27879618/the-value-of-detecting-asymptomatic-signs-of-myocardial-ischemia-in-patients-with-coronary-artery-disease-in-outpatient-cardiac-rehabilitation
#16
Patricia Lounsbury, Ahmed S Elokda, Jennifer M Bunning, Ross Arena, Ellen E I Gordon
BACKGROUND: Electrocardiographic (ECG) monitored outpatient cardiac rehabilitation (OP-CR) is routinely performed following a variety of cardiovascular procedures and conditions. OBJECTIVE: The aim of this study is to determine if diagnostic-quality ECG monitoring in patients with coronary artery disease (CAD) during OP-CR is useful in identifying asymptomatic myocardial ischemia, resulting in change(s) in care or medical management. METHODS: A retrospective analysis of ECG monitoring was done on all OP-CR patients diagnosed with CAD (n = 1213) from January 2000 through June 2013...
November 22, 2016: Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/27836292/impact-of-coronary-collateral-circulation-on-angiographic-in-stent-restenosis-in-patients-with-stable-coronary-artery-disease-and-chronic-total-occlusion
#17
Zhen Kun Yang, Ying Shen, Jian Hu, Qi Zhang, Feng Hua Ding, Rui Yan Zhang, Lin Lu, Wei Feng Shen
OBJECTIVE: This study aimed to evaluate the relationship between coronary collateralization and in-stent restenosis (ISR) in stable coronary artery disease patients with chronic total occlusion (CTO) after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation. METHODS: The degree of coronary collaterals supplying the distal aspect of a total occlusion from the contra-lateral vessel was graded according to Rentrop classification in 216 patients with stable angina undergoing successful DES based PCI for CTO...
January 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27816119/gender-differences-in-outcomes-and-predictors-of-all-cause-mortality-after-percutaneous-coronary-intervention-data-from-united-kingdom-and-sweden
#18
Vijay Kunadian, Weiliang Qiu, Bo Lagerqvist, Nina Johnston, Hannah Sinclair, Ying Tan, Peter Ludman, Stefan James, Giovanna Sarno
To determine gender differences and predictors of all-cause mortality (30 days and 1 year) after percutaneous coronary intervention (PCI) in patients with stable angina pectoris and acute coronary syndrome (non-ST-elevation myocardial infarction/unstable angina pectoris and ST-elevation myocardial infarction) in the British Cardiovascular Intervention Society (BCIS) and Swedish Coronary Angiography and Angioplasty Registry (SCAAR) data sets, an analysis of prospectively collected data from 2007 to 2011 was performed...
January 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/27810312/percutaneous-coronary-angioplasty-versus-coronary-artery-bypass-grafting-in-treatment-of-unprotected-left-main-stenosis-noble-a-prospective-randomised-open-label-non-inferiority-trial
#19
Timo Mäkikallio, Niels R Holm, Mitchell Lindsay, Mark S Spence, Andrejs Erglis, Ian B A Menown, Thor Trovik, Markku Eskola, Hannu Romppanen, Thomas Kellerth, Jan Ravkilde, Lisette O Jensen, Gintaras Kalinauskas, Rikard B A Linder, Markku Pentikainen, Anders Hervold, Adrian Banning, Azfar Zaman, Jamen Cotton, Erlend Eriksen, Sulev Margus, Henrik T Sørensen, Per H Nielsen, Matti Niemelä, Kari Kervinen, Jens F Lassen, Michael Maeng, Keith Oldroyd, Geoff Berg, Simon J Walsh, Colm G Hanratty, Indulis Kumsars, Peteris Stradins, Terje K Steigen, Ole Fröbert, Alastair N J Graham, Petter C Endresen, Matthias Corbascio, Olli Kajander, Uday Trivedi, Juha Hartikainen, Vesa Anttila, David Hildick-Smith, Leif Thuesen, Evald H Christiansen
BACKGROUND: Coronary artery bypass grafting (CABG) is the standard treatment for revascularisation in patients with left main coronary artery disease, but use of percutaneous coronary intervention (PCI) for this indication is increasing. We aimed to compare PCI and CABG for treatment of left main coronary artery disease. METHODS: In this prospective, randomised, open-label, non-inferiority trial, patients with left main coronary artery disease were enrolled in 36 centres in northern Europe and randomised 1:1 to treatment with PCI or CABG...
December 3, 2016: Lancet
https://www.readbyqxmd.com/read/27794429/alternative-complement-pathway-activation-during-invasive-coronary-procedures-in-acute-myocardial-infarction-and-stable-angina-pectoris
#20
Zsófia Horváth, Dorottya Csuka, Katarina Vargova, Andrea Kovács, Sarolta Leé, Lilian Varga, István Préda, Emese Tóth Zsámboki, Zoltán Prohászka, Róbert Gábor Kiss
The effect of invasive percutaneous coronary procedures on complement activation has not been elucidated. We enrolled stable angina patients with elective percutaneous coronary intervention (SA-PCI, n=24), diagnostic coronary angiography (CA, n=52) and 23 patients with ST segment elevation myocardial infarction and primary PCI (STEMI-PCI). Complement activation products (C1rC1sC1inh, C3bBbP and SC5b-9) were measured on admission, 6 and 24h after coronary procedures. The alternative pathway product, C3bBbP significantly and reversibly increased 6h after elective PCI (baseline: 7...
December 1, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
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