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pci in stable angina

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https://www.readbyqxmd.com/read/28185167/challenges-with-evidence-based-management-of-stable-ischemic-heart-disease
#1
REVIEW
Amit V Patel, Sripal Bangalore
PURPOSE OF REVIEW: Stable ischemic heart disease (SIHD) is a highly prevalent condition associated with increased costs, morbidity, and mortality. Management goals of SIHD can broadly be thought of in terms of improving prognosis and/or improving symptoms. Treatment options include medical therapy as well as revascularization, either with percutaneous coronary intervention or coronary artery bypass grafting. Herein, we will review the current evidence base for treatment of SIHD as well as its challenges and discuss ongoing studies to help address some of these knowledge gaps...
February 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28167479/evaluation-on-curative-effect-and-safety-of-interventional-treatment-for-patients-with-acute-myocardial-infarction
#2
Yinchuan Zhu, Jianmin Tang, Feifei Pei
To evaluate the effectiveness and recent safety of emergency and selective percutaneous coronary intervention (PCI) in elderly patients (>80 years old) with acute myocardial infarction (AMI). 120 elderly patients with coronary heart disease (CHD) were divided into AMI group (with 55 cases) and non-myocardial infarction group (control group with 65 cases). Among the AMI group, there were 18 cases underwent emergency PCI within 12 hours after the onset, (AMI emergency PCI group), the rest 37 cases were AMI selective PCI group...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28154590/serum-irisin-level-can-predict-the-severity-of-coronary-artery-disease-in-patients-with-stable-angina
#3
Tolga Han Efe, Burak Açar, Ahmet Göktuğ Ertem, Kadriye Gayretli Yayla, Engin Algül, Çağrı Yayla, Sefa Ünal, Murat Bilgin, Tolga Çimen, Özgür Kirbaş, Ekrem Yeter
BACKGROUND AND OBJECTIVES: The recently discovered myokine irisin has a proposed role in adipose tissue metabolism. The aim of this study was to evaluate the relationship between serum irisin level and the coronary artery severity in patients with stable coronary artery disease (CAD). SUBJECTS AND METHODS: Sixty-three patients who underwent coronary angiography (CA) diagnosed with stable CAD and twenty-six patients with normal coronary artery (NCA) were enrolled in the study...
January 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/28145609/evaluation-of-clinical-outcomes-after-combo-stent-treatment-in-patients-presenting-with-acute-coronary-syndrome
#4
Deborah N Kalkman, Pier Woudstra, Huangling Lu, Ian B A Menown, Peter den Heijer, Harry Suryapranata, Andrés Iñiguez, Karin E Arkenbout, Arnoud W J Van't Hof, Philippe Muller, Andrejs Erglis, Jan G Tijssen, Marcel A M Beijk, Robbert J de Winter
BACKGROUND: Patients presenting with acute coronary syndrome (ACS) are at increased risk of complications after percutaneous coronary intervention with stent placement compared to patients with stable angina (SA) treated in an elective setting. The novel pro-healing COMBO stent is a bio-engineered drug eluting stent designed to promote vessel healing. Therefore, the stent may reduce this difference in clinical outcomes between elective and ACS-patients and prevent late stent thrombosis...
February 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28129736/identification-of-new-biosignatures-for-clinical-outcomes-in-stable-coronary-artery-disease-the-study-protocol-and-initial-observations-of-a-prospective-follow-up-study-in-taiwan
#5
Hsin-Bang Leu, Wei-Hsian Yin, Wei-Kung Tseng, Yen-Wen Wu, Tsung-Hsien Lin, Hung-I Yeh, Kuan-Cheng Chang, Ji-Hung Wang, Chau-Chung Wu, Jaw-Wen Chen
BACKGROUND: Either classic or novel biomarkers have not been well investigated for clinical outcomes of coronary artery disease (CAD) in Asian people especially ethnic Chinese. We reported here a prospective national-based follow-up study that aims to elucidate the clinical profiles and to identify the new biosignatures (especially the non-lipid profile and inflammatory biomakers) for future clinical outcomes in a sizable cohort of stable CAD patients in Taiwan. METHODS: A total of 2500 CAD patients under stable condition after successful percutaneous coronary intervention will be enrolled for clinical data collection and blood/urine sampling in northern, southern, western, or eastern part of Taiwan between 2012 and 2017...
January 28, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28120157/subclinical-markers-of-cardiovascular-disease-predict-adverse-outcomes-in-chronic-kidney-disease-patients-with-normal-left-ventricular-ejection-fraction
#6
Samir Sulemane, Vasileios F Panoulas, Athanasios Bratsas, Julia Grapsa, Edwina A Brown, Petros Nihoyannopoulos
Emerging cardiovascular biomarkers, such as speckle tracking echocardiography (STE) and aortic pulse wave velocity (aPWV), have recently demonstrated the presence of subclinical left ventricular dysfunction and arterial stiffening in patients with chronic kidney disease (CKD) and no previous cardiovascular history. However, limited information exists on the prognostic impact of these biomarkers. We aimed to investigate whether STE and aPWV predict major adverse cardiac events (MACE) in this patient population...
January 24, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28100874/efficacy-of-multidetector-computed-tomography-to-predict-periprocedural-myocardial-injury-after-percutaneous-coronary-intervention-for-chronic-total-occlusion
#7
Eisuke Usui, Tetsumin Lee, Tadashi Murai, Yoshihisa Kanaji, Junji Matsuda, Makoto Araki, Taishi Yonetsu, Yosuke Yamakami, Shigeki Kimura, Tsunekazu Kakuta
Specific signatures of culprit lesions detected on multidetector computed tomography (MDCT) were identified as predictors of periprocedural myocardial injury (PMI) after percutaneous coronary intervention (PCI) in patients with stable angina; PMI has been shown to be associated with a worse prognosis. We investigated the association between preprocedural culprit lesion characteristics, assessed by MDCT, and PMI after PCI for chronic total occlusion (CTO). From three medical centers, 81 patients who underwent pre-PCI MDCT and CTO PCI, and systematic cardiac troponin (cTn) sampling before and after PCI, were included...
February 7, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28092977/hypertension-is-associated-with-increased-mortality-in-patients-with-ischaemic-heart-disease-after-revascularization-with-percutaneous-coronary-intervention-a-report-from-scaar
#8
Ott Saluveer, Björn Redfors, Oskar Angerås, Christian Dworeck, Inger Haraldsson, Charlotta Ljungman, Petur Petursson, Jacob Odenstedt, Dan Ioanes, Peter Lundgren, Sebastian Völz, Truls Råmunddal, Bert Andersson, Elmir Omerovic, Niklas Bergh
BACKGROUND: The prognostic role of hypertension on long-term survival after percutaneous coronary intervention (PCI) is limited and inconsistent. We hypothesize that hypertension increases long-term mortality after PCI. METHODS: We analyzed data from SCAAR (Swedish Coronary Angiography and Angioplasty Registry) for all consecutive patients admitted coronary care units in Sweden between January 1995 and May 2013 and who underwent PCI due to ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI)/unstable angina (UA) or stable angina pectoris...
January 16, 2017: Blood Pressure
https://www.readbyqxmd.com/read/28076449/long-term-follow-up-of-patients-after-percutaneous-coronary-intervention-with-everolimus-eluting-bioresorbable-vascular-scaffold
#9
Rafael Alexandre Meneguz-Moreno, José de Ribamar Costa, Freddy Antônio Britto Moscoso, Rodolfo Staico, Luiz Fernando Leite Tanajura, Marinella Patrizia Centemero, Auréa Jacob Chaves, Andrea Claudia Leão de Sousa Abizaid, Amanda Guerra de Moraes Rego E Sousa, Alexandre Antonio Cunha Abizaid
Background: Bioresorbable vascular scaffolds (BVS) were developed to improve the long-term results of percutaneous coronary intervention, restoring vasomotion. Objectives: To report very late follow-up of everolimus-eluting Absorb BVS (Abbott Vascular, Santa Clara, USA) in our center. Methods: Observational retrospective study, in a single Brazilian center, from August 2011 to October 2013, including 49 patients submitted to Absorb BVS implantation...
January 9, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28042404/in-hospital-and-one-year-clinical-outcome-of-percutaneous-coronary-intervention-in-a-tertiary-hospital-in-oman-oman-pci-registry
#10
Prashanth Panduranga, Majdah Al-Rashidi, Fatma Al-Hajri
OBJECTIVES: The aim of the study was to investigate the in-hospital and one-year clinical outcome of patients treated with percutaneous coronary intervention (PCI) in a tertiary hospital in Oman. METHODS: We conducted a retrospective, single-center, observational study looking at patients > 18 years old who underwent a PCI from 1 January to 31 December 2013. The primary end point was the occurrence of a major adverse cardiovascular event (MACE), defined as death, any myocardial infarction (MI), cerebrovascular accident (CVA), and target vessel revascularization (TVR) with either repeat PCI or coronary artery bypass surgery (CABG)...
January 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28034517/impact-of-paradoxical-decrease-in-high-density-lipoprotein-cholesterol-levels-after-statin-therapy-on-major-adverse-cardiovascular-events-in-patients-with-stable-angina-pectoris
#11
Kenshi Hirayama, Tomoyuki Ota, Kazuhiro Harada, Yohei Shibata, Yosuke Tatami, Shingo Harata, Kazuhiro Kawashima, Ayako Kunimura, Yusaku Shimbo, Yohei Takayama, Toshiki Kawamiya, Dai Yamamoto, Naohiro Osugi, Susumu Suzuki, Hideki Ishii, Toyoaki Murohara
PURPOSE: Statin therapy usually increases HDL-C levels. However, a paradoxical decrease in HDL-C levels after statin therapy is often seen in clinical settings. The relationship between a paradoxical decrease in HDL-C levels after statin therapy and adverse cardiovascular events in patients with stable angina pectoris (SAP) is not well understood. The purpose of this study was to analyze the relationship between paradoxical HDL-C decreases after statin therapy and major adverse cardiovascular events (MACEs) in patients undergoing percutaneous coronary intervention (PCI) for SAP...
December 26, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/28031149/diagnostic-and-prognostic-value-of-a-careful-symptom-evaluation-and-high-sensitive-troponin-in-patients-with-suspected-stable-angina-pectoris-without-prior-cardiovascular-disease
#12
Debbie M Madsen, Axel C P Diederichsen, Susanne E Hosbond, Oke Gerke, Hans Mickley
BACKGROUND AND AIMS: Typical angina pectoris (AP) and high-sensitive troponin I (hs-TnI) are independently associated with coronary artery disease (CAD) and future cardiovascular events (CVE). This study aimed to assess the individual and combined diagnostic and prognostic impact of symptoms and hs-TnI in stable chest pain patients without prior cardiovascular disease. METHODS: During a one-year period, 487 patients with suspected stable AP underwent invasive or CT-coronary angiography (significant stenosis ≥50%)...
November 28, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/28017291/rationale-design-and-goals-of-the-heartflow-assessing-diagnostic-value-of-non-invasive-ffrct-in-coronary-care-advance-registry
#13
Kavitha M Chinnaiyan, Takashi Akasaka, Tetsuya Amano, Jeroen J Bax, Philipp Blanke, Bernard De Bruyne, Tomohiro Kawasaki, Jonathon Leipsic, Hitoshi Matsuo, Yoshihiro Morino, Koen Nieman, Bjarne L Norgaard, Manesh R Patel, Gianluca Pontone, Mark Rabbat, Campbell Rogers, Neils Peter Sand, Gilbert Raff
BACKGROUND: Coronary CT angiography (CTA) is a reliable tool for the detection of coronary artery disease (CAD) that conveys significant prognostic information. It does not provide data on the hemodynamic significance of a given lesion, particularly in intermediate-grade stenosis. Fractional flow reserve by CT (FFRCT) can accurately predict the hemodynamic significance of coronary lesions. The primary objective of this registry is to determine whether the integration of FFRCT as an adjunct to coronary CTA will lead to a significant change in the management of CAD in patients with stable angina...
January 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28005559/the-impact-of-blood-pressure-variability-on-coronary-plaque-vulnerability-in-stable-angina-an-analysis-using-optical-coherence-tomography
#14
Rie Aoyama, Hitoshi Takano, Keishi Suzuki, Yoshiaki Kubota, Keisuke Inui, Yukichi Tokita, Wataru Shimizu
BACKGROUND: Blood pressure variability (BPV), especially visit-to-visit BPV, has been reported to be a risk factor for cardiovascular disease. The impact of BPV on coronary plaque vulnerability remains uncertain. The aim of this study was to investigate the relationship between BPV and coronary plaque vulnerability. PATIENTS AND METHODS: From August 2013 to May 2014, 36 patients with both hypertension and stable angina pectoris who underwent a percutaneous coronary intervention guided by frequency-domain optical coherence tomography were investigated retrospectively...
December 21, 2016: Coronary Artery Disease
https://www.readbyqxmd.com/read/27998900/randomised-double-blind-placebo-controlled-study-investigating-the-effects-of-inorganic-nitrate-on-vascular-function-platelet-reactivity-and-restenosis-in-stable-angina-protocol-of-the-nitrate-oct-study
#15
Krishnaraj S Rathod, Daniel A Jones, T J A Van-Eijl, Hilda Tsang, Helen Warren, Stephen M Hamshere, Vikas Kapil, Ajay K Jain, Andrew Deaner, Neil Poulter, Mark J Caulfield, Anthony Mathur, Amrita Ahluwalia
INTRODUCTION: The mainstay treatment for reducing the symptoms of angina and long-term risk of heart attacks in patients with heart disease is stent implantation in the diseased coronary artery. While this procedure has revolutionised treatment, the incidence of secondary events remains a concern. These repeat events are thought to be due, in part, to continued enhanced platelet reactivity, endothelial dysfunction and ultimately restenosis of the stented artery. In this study, we will investigate whether a once a day inorganic nitrate administration might favourably modulate platelet reactivity and endothelial function leading to a decrease in restenosis...
December 20, 2016: BMJ Open
https://www.readbyqxmd.com/read/27973330/three-dimensional-volumetric-assessment-of-coronary-artery-calcification-in-patients-with-stable-coronary-artery-disease-by-oct
#16
Parasuram Krishnamoorthy, Yuliya Vengrenyuk, Hiroshi Ueda, Takahiro Yoshimura, Jacobo Pena, Sadako Motoyama, Usman Baber, Choudhury Hasan, Srinivas Kesanakurthy, Joseph M Sweeny, Samin K Sharma, Jagat Narula, Jason C Kovacic, Annapoorna S Kini
AIMS: There is a lack of reliable technique to quantify coronary artery calcification (CAC). Hence, we used Optical Coherence Tomography (OCT) to quantitate 3- dimensional CAC volume to examine its association with plaque characteristics. METHODS AND RESULTS: A total of 250 patients with stable angina undergoing OCT imaging before PCI were included. CAC volume was calculated from every frame of the culprit lesion and divided into tertiles (low, intermediate and high)...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27969855/tct-496-differences-in-quantitative-coronary-angiographic-qca-characteristics-of-coronary-artery-disease-between-human-immunodeficiency-virus-hiv-patients-presenting-with-acute-coronary-syndrome-acs-and-stable-angina-pectoris-sap-undergoing-percutaneous-coronary
#17
Kleanthis Theodoropoulos, Omar Meelu, Marco Mennuni, Samantha Sartori, Jennifer Yu, Usman Baber, Giulio Stefanini, Ioannis Mastoris, Pedro Moreno, George Dangas, Roxana Mehran, Samin Sharma, Annapoorna Kini
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27914491/impact-of-lesion-characteristics-on-the-prediction-of-optimal-poststent-fractional-flow-reserve
#18
Hirohiko Ando, Hiroaki Takashima, Akihiro Suzuki, Shinichiro Sakurai, Soichiro Kumagai, Akiyoshi Kurita, Katsuhisa Waseda, Tetsuya Amano
BACKGROUND: Poststent fractional flow reserve (FFR) is a useful indicator of optimal percutaneous coronary intervention, and higher poststent FFR is associated with favorable long-term clinical outcome. However, little is known about the factors influencing poststent FFR. The purpose of this study was to determine the impact of lesion characteristics on poststent FFR. METHODS: For patients who had scheduled stent implantation for stable angina, FFR measurements at maximum hyperemia were performed before and after coronary stent implantation...
December 2016: American Heart Journal
https://www.readbyqxmd.com/read/27913753/neutrophil-derived-microparticles-are-released-into-the-coronary-circulation-following-percutaneous-coronary-intervention-in-acute-coronary-syndrome-patients
#19
Gonzalo J Martínez, Jennifer Y Barraclough, Shirley Nakhla, Vivian Kienzle, Stacy Robertson, Ziad Mallat, David S Celermajer, Sanjay Patel
To evaluate (i) local coronary and systemic levels of microparticles (MP) in acute coronary syndrome (ACS) and stable angina pectoris (SAP) patients and (ii) their release after plaque disruption with percutaneous coronary intervention (PCI). MP are small vesicles originating from plasma membranes of cells after activation or apoptosis and are implicated in the pathogenesis of atherosclerosis. Neutrophils play a role in plaque destabilization and shed neutrophil-derived MP that have the potential to drive significant proinflammatory and thrombotic downstream effects...
February 28, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/27912733/the-effect-of-percutaneous-coronary-intervention-on-habitual-physical-activity-in-older-patients
#20
Sarah J Charman, Vincent T van Hees, Louise Quinn, Joseph R Dunford, Bilal Bawamia, Murugapathy Veerasamy, Michael I Trenell, Djordje G Jakovljevic, Vijay Kunadian
BACKGROUND: Given the ongoing burden of cardiovascular disease and an ageing population, physical activity in patients with coronary artery disease needs to be emphasized. This study assessed whether sedentary behaviour and physical activity levels differed among older patients (≥75 years) following percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) consisting of ST-segment elevation myocardial infarction (STEMI) and non STEMI (NSTEMI) versus an elective admission control group of stable angina patients...
December 3, 2016: BMC Cardiovascular Disorders
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