K T Whang, P M Steinwald, J C White, E S Nylen, R H Snider, G L Simon, R L Goldberg, K L Becker
High serum levels of the calcitonin (CT) prohormone, procalcitonin (pro-CT), and its component peptides occur in systemic inflammation and sepsis. Using two different assays, we undertook a prospective study to determine the utility of serum precalcitonin peptides (pre-CT) as markers in this condition. Twenty-nine patients meeting criteria for the systemic inflammatory response syndrome were studied daily in two intensive care units. Sera were collected, and APACHE II scores were determined until recovery or death...
September 1998: Journal of Clinical Endocrinology and Metabolism