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https://www.readbyqxmd.com/read/29141566/perioperative-levels-of-adiponectin-and-oxidative-stress-in-patients-undergoing-laparoscopic-abdominal-surgery-for-cancer
#1
Cosimo Chelazzi, Gianluca Villa, Paola Mancinelli, Matteo Becatti, Maria Boddi, Mirella Coppo, Stefano Romagnoli
BACKGROUND: Low circulating levels of adiponectin are associated with the occurrence of infection after surgery in patients with cancer. Data are lacking on whether surgical stress is associated with a reduction in circulating levels of adiponectin. Furthermore, the relationships between oxidative stress and postoperative complications have not been investigated. OBJECTIVE: The aim of this study was to evaluate the pre-, intra-, and postoperative levels of adiponectin in patients who underwent major abdominal surgery for malignancy and their association with postoperative complications...
November 14, 2017: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/29131462/outcomes-of-liver-transplantation-in-pediatric-recipients-with-cardiovascular-disease
#2
Márcio Miranda Brito, Joao Seda Neto, Eduardo A Fonseca, Renata Pugliese, Vera B Danesi, Helry L Candido, Adriana Porta, Cristian V B Borges, Gilda Porta, Paulo Chapchap, Irene Kazue Miura
LT exerts considerable stress on the heart perioperatively. Limited data exist on impact of cardiovascular diseases on LT children. This study evaluated the outcomes of children with CVD who underwent LT and compared with pretransplant findings. From 518 LT recipients, 82 (15.8%) had CVD. Sixty patients were classified as low-risk adjustment for congenital heart surgery 1 (RACHS 1 and 2). Five patients were classified as RACHS ≥3. The most common echocardiographic finding in the CVD patients (25/82) was ASD...
November 12, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29129842/association-of-perioperative-redox-balance-on-long-term-outcome-in-patients-undergoing-lung-resection
#3
Osamu Araki, Yuji Matsumura, Takashi Inoue, Yoko Karube, Sumiko Maeda, Satoru Kobayashi, Masayuki Chida
PURPOSE: We examined whether redox balance during the perioperative period is associated with long-term survival of patients after undergoing lung resection. METHODS: Patients who underwent surgery for lung cancer from January to June 2013 at our institution were investigated. Serum was collected during the operation, and on postoperative day (POD) 3 and 7, and the levels of derivatives of reactive oxygen metabolites (d-ROMs) and biologic antioxidant potential (BAP) were measured...
November 10, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29128486/lower-dose-of-sufentanil-does-not-enhance-fast-track-significantly-a-randomized-study
#4
Rajesh Bhavsar, Pia Katarina Ryhammer, Jacob Greisen, Carl-Johan Jakobsen
OBJECTIVE: Adjustment in the doses of opioids has been a focus of interest for achieving better fast-track conditions in cardiac anesthesia, but relatively sparse information exists on the potential effect of psychologic and behavioral factors, such as stress, anxiety, and type of personality, on anesthesia requirements and patient turnover in the cardiac recovery unit (CRU); to the authors' knowledge, this particular focus has not been systematically investigated. In this randomized study, the authors tested the hypothesis that low-dose sufentanil, compared with a standard dose, can improve fast-track parameters and the overall quality of recovery...
August 9, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29118462/predictive-role-of-f2-isoprostanes-as-biomarkers-for-brain-damage-after-neonatal-surgery
#5
L J Stolwijk, P M A Lemmers, M Y A van Herwaarden, D C van der Zee, F van Bel, F Groenendaal, M L Tataranno, M Calderisi, M Longini, F Bazzini, M J N L Benders, G Buonocore
Objective: Neonates have a high risk of oxidative stress during anesthetic procedures. The predictive role of oxidative stress biomarkers on the occurrence of brain injury in the perioperative period has not been reported before. Methods: A prospective cohort study of patients requiring major surgery in the neonatal period was conducted. Biomarker levels of nonprotein-bound iron (NPBI) in plasma and F2-isoprostane in plasma and urine before and after surgical intervention were determined...
2017: Disease Markers
https://www.readbyqxmd.com/read/29108091/effects-of-low-dose-epinephrine-on-perioperative-hemostasis-and-inflammatory-reaction-in-major-surgeries-a%C3%A2-randomized%C3%A2-clinical-trial
#6
J L Liu, W N Zeng, F Y Wang, C Chen, X Y Gong, H Yang, Z J Tan, X L Jia, L Yang
BACKGROUND: Haemostasis, thrombosis, and surgical stress-induced immune reaction are important for perioperative morbidity and recovery in major surgeries. OBJECTIVES: This study aimed to evaluate the effects of combined administration of low-dose epinephrine (LDEPI) plus tranexamic acid (TXA) on perioperative blood loss, thromboembolic complications, and inflammatory response in total hip arthroplasty (THA). PATIENTS /METHODS: Patients scheduled for THA (n = 195) were randomized into 3 interventions: intravenous (IV) LDEPI plus TXA (Group IV); topical (TP) diluted-epinephrine plus TXA (Group TP); and TXA alone as control (CT) (Group CT)...
November 6, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29107119/the-impact-of-carbon-dioxide-pneumoperitoneum-on-ovarian-ischemia-reperfusion-injury-during-laparoscopic-surgery-a-preliminary-study
#7
Ali Akdemir, Enes Taylan, Cagdas Sahin, Banu Ozgurel, Ayfer Karlitepe, Osman Zekioglu, Gulinnaz Ercan
STUDY OBJECTIVE: To investigate whether carbon dioxide (CO2) pneumoperitoneum cause ischemia-reperfusion injury to the ovaries during laparoscopic surgery. DESIGN: Prospective controlled clinical study (Canadian Task Force classification II-1). SETTING: Tertiary Academic Center. PATIENTS: Premenopausal women who underwent hysterectomy with bilateral salpingo-oophorectomy (HSO) via open abdominal and laparoscopic approaches between 2014 and 2015...
October 26, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29104182/lipid-peroxidation-in-cardiac-surgery-towards-consensus-on-biomonitoring-diagnostic-tools-and-therapeutic-implementation
#8
Rosalba Romano, Simona M Cristescu, Terence H Risby, Nandor Marczin
This review focuses on oxidative stress and more specifically lipid peroxidation in cardiac surgery, one of the fundamental theories of perioperative complications. We present the molecular pathways leading to lipid peroxidation and integrate analytical methods that allow detection of lipid peroxidation markers in the fluid phase with those focusing on volatile compounds in exhaled breath. In order to explore the accumulated data in the literature, we present a systematic review of quantitative analysis of malondialdehyde (MDA), a widely used lipid peroxidation product at various stages of cardiac surgery...
November 6, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/29099565/implementation-of-an-enhanced-recovery-after-surgery-program-for-colorectal-surgery-at-a-community-teaching-hospital
#9
Mallory S Bray, Angela L Appel, Kara J Kallies, Andrew J Borgert, Brittany A Zinnel, Stephen B Shapiro
INTRODUCTION: Perioperative programs aimed at decreasing surgical stress to colorectal patients can reduce hospital length of stay and morbidity while improving the patient’s perception of the surgical experience. Our goal was to transform patient care from a perioperative platform based on individual physician and nurse choice to a standardized evidence-based Enhanced Recovery After Surgery (ERAS) protocol for all patients undergoing elective colorectal resections. METHODS: An institutional review board-approved retrospective review was performed for the first 12 months of ERAS protocol-driven patient care in 2014 and compared to the prior 12 months (2013) of individual choice managed care...
February 2017: WMJ: Official Publication of the State Medical Society of Wisconsin
https://www.readbyqxmd.com/read/29098955/perioperative-takotsubo-cardiomyopathy-a-systematic-review-of-published-cases
#10
Shvetank Agarwal, Matthew G Bean, J Steven Hata, Manuel R Castresana
Takotsubo cardiomyopathy (TCM) is a condition that is characterized as a transient ventricular dysfunction in the absence of obstructive coronary artery disease (CAD) and is usually triggered by an acute medical illness or intense physical or emotional stress. Multiple cases of perioperative TCM (pTCM) have been reported from around the world, but a qualitative analysis of these cases has not yet been done. For this systematic review, we searched PubMed for case reports and case series of pTCM published from 1966 to April 2015 with the objective being to evaluate whether differences in demographics, clinical features and outcomes exist between pTCM and nonperioperative (npTCM), as well as to attempt to identify any predictors of the severe form of pTCM, which requires mechanical circulatory support (MCS) devices or leads to death...
December 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29088950/neurosurgical-applications-of-viscoelastic-hemostatic-assays
#11
Svetlana Kvint, James Schuster, Monisha A Kumar
Patients taking antithrombotic agents are very common in neurosurgical practice. The perioperative management of these patients can be extremely challenging especially as newer agents, with poorly defined laboratory monitoring and reversal strategies, become more prevalent. This is especially true with emergent cases in which rapid reversal of anticoagulation is required and the patient's exact medical history is not available. With an aging patient population and the associated increase in diseases such as atrial fibrillation, it is expected that the use of these agents will continue to rise in coming years...
November 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/29077924/perioperative-behavioral-therapy-and-pelvic-muscle-strengthening-do-not-enhance-quality-of-life-after-pelvic-surgery-secondary-report-of-a-randomized-controlled-trial
#12
RANDOMIZED CONTROLLED TRIAL
Alison C Weidner, Matthew D Barber, Alayne Markland, David D Rahn, Yvonne Hsu, Elizabeth R Mueller, Sharon Jakus-Waldman, Keisha Y Dyer, Lauren Klein Warren, Marie G Gantz, Susie Meikle
Background: There is significant need for trials evaluating the long-term effectiveness of a rigorous program of perioperative behavioral therapy with pelvic floor muscle training (BPMT) in women undergoing transvaginal reconstructive surgery for prolapse. Objective: The purpose of this study was to evaluate the effect of perioperative BPMT on health-related quality of life (HRQOL) and sexual function following vaginal surgery for pelvic organ prolapse (POP) and stress urinary incontinence (SUI)...
November 1, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29069660/the-tiloop%C3%A2-male-sling-did-we-forejudge
#13
Tanja Hüsch, Alexander Kretschmer, Frauke Thomsen, Dominik Kronlachner, Martin Kurosch, Alice Obaje, Ralf Anding, Ruth Kirschner-Hermanns, Tobias Pottek, Achim Rose, Roberto Olianas, Alexander Friedl, Wilhelm Hübner, Roland Homberg, Jesco Pfitzenmaier, Ulrich Grein, Fabian Queissert, Carsten Maik Naumann, Josef Schweiger, Carola Wotzka, Joanne Nyarangi-Dix, Bernhard Brehmer, Kurt Ulm, Ricarda M Bauer, Axel Haferkamp
INTRODUCTION: To evaluate the safety and efficacy of the TiLOOP® male sling (pfm medical, Cologne, Germany) used in the treatment for male stress urinary incontinence (SUI). MATERIAL AND METHODS: We retrospectively evaluated a total of 34 patients with a TiLOOP® male sling. Perioperative complication rates were assessed and validated questionnaires were prospectively evaluated to assess quality of life and satisfaction rate. Outcome and complication rates were analysed by using descriptive statistics...
October 26, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/29062649/multimodal-analgesia-in-breast-surgical-procedures-technical-and-pharmacological-considerations-for-liposomal-bupivacaine-use
#14
Anoushka M Afonso, Martin I Newman, Neil Seeley, Jacob Hutchins, Kevin L Smith, Gabriel Mena, Jesse C Selber, Michel H Saint-Cyr, Jeffrey C Gadsden
Enhanced recovery after surgery is a multidisciplinary perioperative clinical pathway that uses evidence-based interventions to improve the patient experience as well as increase satisfaction, reduce costs, mitigate the surgical stress response, accelerate functional recovery, and decrease perioperative complications. One of the most important elements of enhanced recovery pathways is multimodal pain management. Herein, aspects relating to multimodal analgesia following breast surgical procedures are discussed with the understanding that treatment decisions should be individualized and guided by sound clinical judgment...
September 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29051981/preoperative-optimization-of-patients-with-inflammatory-bowel-disease-undergoing-gastrointestinal-surgery-a-systematic-review
#15
REVIEW
Marie Strøm Zangenberg, Nir Horesh, Uri Kopylov, Alaa El-Hussuna
PURPOSE: Surgical management of inflammatory bowel disease (IBD) is a challenging task. The aim of preoperative optimization (PO) is to decrease the risk of complications and reduce the length of postoperative stay. The aim of this study was to review and grade the available evidence, attain clear recommendations, and point out potential future research. METHODS: Studies were identified from electronic databases (PubMed, Embase, and Cochrane Library) and scanning reference lists in relevant papers...
October 19, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29032312/advanced-oxidation-protein-products-induce-s-phase-arrest-of-hepatocytes-via-the-ros-dependent-%C3%AE-catenin-cdk2-mediated-pathway
#16
Shibo Sun, Fang Xie, Xiaoping Xu, Qing Cai, Qifan Zhang, Zhonglin Cui, Yujian Zheng, Jie Zhou
Liver regeneration has important clinical importance in the setting of partial hepatectomy (PH). Following PH, quiescent hepatocytes can reenter cell cycle to restore liver mass. Hepatocyte cell cycle progression, as the basic motivations of liver regeneration, can be disrupted by multiple pathological factors such as oxidative stress. This study aimed to evaluate the role of advanced oxidation protein products (AOPP) in S-phase arrest in hepatocytes. Serum AOPP level were measured during the perioperative period of PH in 33 patients with hepatocellular carcinoma (HCC)...
October 6, 2017: Redox Biology
https://www.readbyqxmd.com/read/29018652/anastomotic-aneurysm-formation-after-high-flow-bypass-surgery-a-case-report-with-histopathological-study
#17
Tatsuya Uchida, Masanori Yoshino, Shinji Ito, Takayuki Hara
Bypass surgery is often used in the treatment of large and giant aneurysms. Major complications that often arise during the perioperative period include cranial nerve palsy, ischemic complications, and hyperperfusion. However, there have been a few reports about late onset complications such as anastomotic aneurysms. In particular, anastomotic aneurysm after high flow bypasses has never been reported. A 57-year-old woman who had been suffering from left eye pain was diagnosed with a large aneurysm of the left internal carotid artery (ICA) in the cavernous portion...
October 2017: NMC Case Rep J
https://www.readbyqxmd.com/read/28993084/perioperative-fractures-in-cementless-total-hip-arthroplasty-using-the-direct-anterior-minimally-invasive-approach-reduced-risk-with-short-stems
#18
Michael Dietrich, Method Kabelitz, Claudio Dora, Patrick O Zingg
BACKGROUND: The direct minimally invasive anterior approach (DMIAA) and the use of uncemented stems demonstrated an increase in intraoperative fractures in recent literature. Whether the different design of the stems additionally influences the incidence of perioperative local complications, was the goal of this study. METHODS: From January 2008 until June 2010, all patients undergoing primary cementless total hip arthroplasty, using a DMIAA, were consecutively included...
September 19, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28985025/multidisciplinary-approach-to-cardiac-and-pulmonary-vascular-disease-risk-assessment-in-liver-transplantation-an-evaluation-of-the-evidence-and-consensus-recommendations
#19
Lisa B VanWagner, Matthew E Harinstein, James R Runo, Christopher Darling, Marina Serper, Shelley Hall, Jon A Kobashigawa, Laura L Hammel
Liver transplant (LT) candidates today are older, have greater medical severity of illness, and have more cardiovascular comorbidities than ever before. In addition, there are specific cardiovascular responses in cirrhosis that can be detrimental to the LT candidate. Cirrhotic cardiomyopathy, a condition characterized by increased cardiac output and a reduced ventricular response to stress, is present in up to 30% of patients with cirrhosis thus challenging perioperative management. Current noninvasive tests that assess for subclinical coronary and myocardial disease have low sensitivity, and altered hemodynamics during the LT surgery can unmask latent cardiovascular disease either intraoperatively or in the immediate postoperative period...
October 6, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28979041/endothelial-glycocalyx-and-cardiopulmonary-bypass
#20
REVIEW
Gerard J Myers, Julie Wegner
On the outer surface of a human cell there is a dense layer of complex carbohydrates called glycocalyx, also referred to as glycans or the sugar coating on the cell surface, which is composed of a complex array of oligosaccharide and polysaccharide glucose chains that are covalently bonded to proteoglycans and lipids bound to the cell membrane surface. Studies of an intact endothelial glycocalyx layer (EGL) have revealed a number of critical functions that relate the importance of this protective layer to vascular integrity and permeability...
September 2017: Journal of Extra-corporeal Technology
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