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https://www.readbyqxmd.com/read/28098112/autosomal-dominant-polycystic-kidney-disease-study-of-clinical-characteristics-in-an-indian-population
#1
Sanjay Vikrant, Anupam Parashar
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary form of kidney disease. Clinical data on this multisystem disorder are scarce from developing countries. We conducted a prospective observational study of the clinical profile of ADPKD patients at a single center over a period of six years. A total of 208 patients were studied. Majority were male (60.6%) and the mean age was 45.8 ± 14.5 years. About 61.5% had early stage (Stages 1-3) of chronic kidney disease (CKD) and 38.5% had advanced CKD (Stages 4 and 5)...
January 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28098069/simultaneous-echinococcal-cyst-and-hepatocellular-carcinoma-without-underlying-liver-disease
#2
Ivan Romic, Bosko Romic, Igor Petrovic
No abstract text is available yet for this article.
December 9, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28097783/type-iii-pleuropulmonary-blastoma-in-a-dicer1-germline-mutation-carrier-the-management-of-residual-lung-cystic-lesions
#3
Ana M Fita, Esther Llinares-Riestra, Ernesto Doménech-Abellán, Mar Bermúdez-Cortés, Ana M Galera-Miñarro, Agueda Bas-Bernal, José L Fuster-Soler
Pleuropulmonary blastoma (PPB) is a rare malignancy of childhood. It often represents a manifestation of a hereditary tumor predisposition syndrome (DICER1 syndrome). Because of its malignant potential, surgical resection of cystic lung lesions is recommended in germline DICER1 mutation carriers. We present a case of a 3-year-old male child with type III PPB successfully managed with ifosfamide, vincristine, actinomycin-D, and doxorubicin (IVADo) chemotherapy and surgery. A heterozygous germline pR688X mutation of DICER1 gene was demonstrated...
January 18, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28097724/unphosphorylated-eiia-ntr-induces-clpap-mediated-degradation-of-rpos-in-azotobacter-vinelandii
#4
Luis Felipe Muriel-Millán, Soledad Moreno, Ramsés Gallegos-Monterrosa, Guadalupe Espín
The nitrogen-related phosphotransferase system (PTS(Ntr) ) is composed of the EI(Ntr) , NPr and EIIA(Ntr) proteins that form a phosphorylation cascade from phosphoenolpyruvate. PTS(Ntr) is a global regulatory system present in most Gram-negative bacteria that controls some pivotal processes such as potassium and phosphate homeostasis, virulence, nitrogen fixation and ABC transport activation. In the soil bacterium Azotobacter vinelandii, unphosphorylated EIIA(Ntr) negatively regulates the expression of genes related to the synthesis of the bioplastic polyester poly-β-hydroxybutyrate (PHB) and cyst-specific lipids alkylresorcinols (ARs)...
January 18, 2017: Molecular Microbiology
https://www.readbyqxmd.com/read/28097642/adrenal-cyst-with-both-m%C3%A3-llerian-and-mesothelial-differentiation-a-clinicopathological-and-immunohistochemical-study-with-implications-for-histogenesis
#5
Łukasz Koperski, Benedykt Szczepankiewicz, Paweł Pihowicz, Łukasz Fus, Ewa Wolińska, Barbara Górnicka
True epithelial-lined cysts are rare forms of adrenal cystic lesions, the pathogenesis of which is still not fully understood. In this report we present a case of an adrenal cyst diagnosed incidentally on imaging in a 31-year-old, previously healthy, obese woman. Due to non-specific hormonal disorders and enlargement of the lesion, a right-sided laparoscopic adrenalectomy was performed. The cyst was lined predominantly by ciliated cuboidal-to-columnar, Müllerian-type epithelium, and focally by flat-to-cuboidal, mesothelium-like lining...
January 18, 2017: Histology and Histopathology
https://www.readbyqxmd.com/read/28097248/transpedicular-endoscopic-surgery-for-lumbar-spinal-synovial-cyst-report-of-two-cases
#6
Guntram Krzok, Albert E Telfeian, Ralf Wagner, Menno Iprenburg
BACKGROUND: Lumbar facet cysts are a benign, degenerative, and fairly uncommon cause for lumbar radiculopathy. The standard surgical treatment for lumbar facet cysts often requires a laminectomy and medial facetectomy which can further destabilize a pathological motion segment. The authors present here a novel technique for transpedicular endoscopic access to the pathology that obviates the need to violate the lamina or facet. METHODS: Two patient cases are described where the lumbar 4-5 facet cysts arise medial to the pedicle...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28096926/congenital-anterior-urethral-diverticulum-presenting-as-a-scrotal-mass-in-a-two-year-old-child
#7
Ali Gürağaç, Hasan Cem Irkilata, Nahit Yunusov, Zafer Demirer
Here, we describe a case of congenital anterior urethral diverticulum (CAUD) in a two-year-old boy, who presented with right inguinoscrotal swelling that mimicked a spermatic cord cyst or hydrocele. Accurate diagnosis was made intraoperatively by retrograde urethrography. Open diverticulectomy and primary urethroplasty were performed for its management. The clinical presentation, diagnosis, and the management of this rare condition is discussed.
November 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28096865/cardiac-hydatid-cyst-without-liver-involvement-a-case-report
#8
Maryam Shojaeifard, Saeid Hosseini, Sarah Hosseini, Hamidreza Pouraliakbar, Hossein Dehghani, Feridoun Noohi
Hydatid disease is a rare parasitic disease, which mainly involves liver then lung tissues. Cardiac involvement is very rare, especially when there is not hepatic involvement. We describe a 47-year-old woman with a history of a lung hydatid cyst who was referred to Rajaei Heart Center, Tehran, Iran in 2012. Her chest computed tomographic scan showed a cardiac mass. Echocardiographic examination illustrated a large, well-defined heterogeneous mass (4.5 × 2.5 cm) in the roof of the right atrium with attachment to the crista terminalis without compressive effect on the inferior and superior venae cavae...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28096857/the-effect-of-fluphenazine-and-thioridazine-on-toxoplasma-gondii-in-vivo
#9
Mehrzad Saraei, Yosef Ghaderi, Tahereh Mosavi, Mojtaba Shahnazi, Marjan Nassiri-Asl, Hassan Jahanihashemi
BACKGROUND: Toxoplasma gondii is the most common parasite causing latent cerebral infections in human. It has been shown that some anti-psychotic drugs are able to inhibit the proliferation of the parasite in in vitro study. There is very limited data regarding the inhibitory effect of anti-psychotics on Toxoplasma in in vivo. In this study, we evaluated anti-Toxoplasma activity of fluphenazine and thioridazine drugs on T. gondii in mice. METHODS: Mice were divided into six groups: Control, sesame as vehicle, thioridazine 10 mg/kg, thioridazine 20 mg/kg, fluphenazine 0...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28096851/acetylcholinesterase-inhibitor-improves-learning-and-memory-impairment-induced-by-toxoplasma-gondii-infection
#10
Hossein Mahmoudvand, Vahid Sheibani, Hossein Keshavarz, Saeedeh Shojaee, Khadijeh Esmaeelpour, Naser Ziaali
BACKGROUND: Here, we established the mouse models of chronic toxoplasmosis by T. gondii Tehran strain to provide a good understanding about defining the possible association between T. gondii exposure and learning and memory impairments. Moreover, as secondary objective of the present study, we hypothesized whether administration of an acetylcholinesterase (AChE) inhibitor could reduce learning and memory impairments induced by T. gondii infection. METHODS: Twenty-four male BALB/c mice were used to establishment of latent toxoplasmosis...
April 2016: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28096839/thoracoscopic-resection-of-a-bronchogenic-cyst-in-a-17-year-old-girl
#11
Roksana Pułtorak, Wojciech Korlacki, Michał Pasierbek, Andrzej Grabowski
Bronchogenic cysts comprise approximately 6% of mediastinal tumors in children. The treatment consists in surgical resection of the cyst. The authors present the case of a 17-year-old girl who was accidentally diagnosed with a mediastinal cyst. The patient was successfully treated with thoracoscopic surgery with good early and late clinical outcomes.
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28096828/intramural-esophageal-tumors
#12
Mariusz P Łochowski, Katarzyna Kozak, Marek Rębowski, Józef Kozak
INTRODUCTION: Intramural esophageal tumors (IET) are located between unchanged mucous membrane and muscularis mucosae. They can be both benign and malignant. AIM: To evaluate diagnostic and therapeutic difficulties of IET. MATERIAL AND METHODS: During the years 2010-2015, 11 patients with IET were treated in our clinic. Diagnostics included gastroscopy, computed tomography of the chest, endoscopic ultrasound (EUS) guided fine needle biopsy, and positron emission tomography (PET) of the esophagus in cases with no histopathological confirmation...
December 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28096605/molecular-and-epidemiological-updates-on-cystic-echinococcosis-infecting-water-buffaloes-from-egypt
#13
Ibrahim Abbas
AIM: Cystic echinococcosis (CE) represents a serious parasitic disease at both animal and public health levels. The majority of reports negated the CE infection in buffaloes from Egypt; however, one study illustrated their infection with G6 genotype (camel strain). The present work contributed to update the epidemiological and molecular knowledge about CE infecting this economically important animal for better understanding of its role in maintaining the Echinococcus life cycle. MATERIALS AND METHODS: A total of 120 slaughtered water buffaloes at Mansoura abattoir, Dakahlia province, Egypt, were inspected for the existence of hydatid cysts...
December 2016: Veterinary World
https://www.readbyqxmd.com/read/28096327/pneumatosis-coli-causing-pneumoperitoneum
#14
Jennifer M Nishimura, Ted Farzaneh, Alessio Pigazzi
This is a case of a 54-year-old gentleman who presented to an outside hospital emergency department with lower abdominal pain. Computed tomography imaging showed a small amount of intraperitoneal free air and cystic pneumatosis coli. He was admitted, managed conservatively with intravenous antibiotics, and then discharged home after his symptoms improved. Elective laparoscopic sigmoid colectomy was subsequently performed with intraoperative findings of partial sigmoid volvulus and extensive pneumatosis coli of the sigmoid colon...
January 17, 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28095872/an-unusual-combined-thymic-carcinoma-composed-of-squamous-cell-carcinoma-and-type-ab-thymoma-a-rare-case-report
#15
Yufeng Jiang, Yang Liu, Xiuying Shi, Xiaoyun Mao, Yang Zhao, Chuifeng Fan
BACKGROUND: Combined thymic carcinoma is a malignant neoplasm of the thymus recently added to the 4th edition of the World Health Organization (WHO) classification of tumors of the lung, pleura, thymus and heart. It involves at least one type of thymic carcinoma and another thymic epithelial tumor. The previously used term "combined thymic epithelial tumor" has been abandoned. CASE PRESENTATION: Here, we present an unusual case of combined thymic carcinoma of the thymus in a 44-year-old male who had suffered from fever, chest pain, chest tightness and shortness of breath...
January 17, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28095662/factors-associated-with-echinococcosis-induced-perioperative-anaphylactic-shock
#16
Jianrong Ye, Qin Zhang, Yan Xuan, Siyu Chen, Long Ma, Yongqiang Zhang, Hong Zheng
This retrospective case-control study explored the factors associated with anaphylactic shock during surgery for cystic echinococcosis (CE) at the First Affiliated Hospital of Xinjiang Medical University between October 2008 and September 2013. Patients who suffered from anaphylactic shock (n=16) were age-matched 3:1 to patients who did not (n=43). Multivariate analysis suggested that IL-4 levels (odds ratio=1.096; 95% confidence interval=1.015-1.185; P=0.02) and cyst size (odds ratio=3.028, 95% confidence interval=1...
December 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28095653/efficacy-of-korean-multipurpose-contact-lens-disinfecting-solutions-against-acanthamoeba-castellanii
#17
Eun-Kyung Moon, Hye-Ryun Park, Fu-Shi Quan, Hyun-Hee Kong
Acanthamoeba keratitis has been increasing in recent years. Main risk factors are contact lens wear and their cleaning solutions. Most contact lens wearers use multipurpose disinfecting solutions (MPDS) for cleansing and disinfecting microorganisms because of its convenience. We determined amoebicidal effects of MPDS made in Korea and their cytotoxicity on human corneal epithelium cells. Fifteen commercial MPDS (A to O) were tested for their amoebicidal effects on Acanthamoeba castellanii trophozoites and cysts by using a most probable number (MPN) technique...
December 2016: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28094850/discriminating-solitary-cysts-from-soft-tissue-lesions-in-mammography-using-a-pretrained-deep-convolutional-neural-network
#18
Thijs Kooi, Bram van Ginneken, Nico Karssemeijer, Ard den Heeten
PURPOSE: It is estimated that 7% of women in the western world will develop palpable breast cysts in their lifetime. Even though cysts have been correlated with risk of developing breast cancer, many of them are benign and do not require follow-up. We develop a method to discriminate benign solitary cysts from malignant masses in digital mammography. We think a system like this can have merit in the clinic as a decision aid or complementary to specialised modalities. METHODS: We employ a deep Convolutional Neural Network (CNN) to classify cyst and mass patches...
January 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28094215/effect-of-decompression-for-patients-with-various-jaw-cysts-based-on-a-three-dimensional-computed-tomography-analysis
#19
Ho-Gul Jeong, Jae Joon Hwang, Sung Hwa Lee, Woong Nam
OBJECTIVES: The aim of this study is to evaluate the effectiveness of decompression according to reduction parameters by measuring cystic volume changes using computed tomography (CT). STUDY DESIGN: We chose patients who had undergone decompression for a cystic lesion of the jaw at the Department of Oral and Maxillofacial Surgery in our dental hospital between 2006 and 2015. All patients had been examined by CT before and after decompression. We measured the volume of cystic lesions using the threshold method and evaluated the volumetric changes after decompression according to various parameters...
December 7, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28093510/de-novo-formation-of-a-symptomatic-arachnoid-cyst-in-an-adult
#20
George M Ibrahim, Naif M Alotaibi, Nir Lipsman, Farshad Nassiri, Leodante da Costa
No abstract text is available yet for this article.
January 17, 2017: Neurology
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