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Morgane Choquet, Emilie Pluquet, Sandrine Castelain, Raphaël Guihéneuf, Véronique Decroix
BACKGROUND: Aggregatibacter aphrophilus, a commensal of the oro-pharyngeal flora and member of the HACEK group of organisms, is an uncommonly encountered clinical pathogen. It has already been described as the causative agent of brain abscesses, empyema, meningitis, sinusitis, otitis media, bacteriemia, pneumonia, osteomyelitis, peritonitis, endocarditis and wound infections. Herein we report the first case of bartholinitis due to A. aphrophilus. CASE PRESENTATION: A 33-year-old woman was admitted for a 3-day genital pain without fever and urinary functional signs...
October 18, 2016: BMC Infectious Diseases
Marta Germán Díaz, José Manuel Moreno Villares, Pilar Gomis Muñoz
Introducción: la nutrición parenteral domiciliaria se ha convertido en un punto clave en el tratamiento de pacientes con fracaso intestinal crónico. A pesar de los importantes avances que se han producido en las últimas décadas, tanto en los accesos vasculares, como en las soluciones empleadas, las infecciones asociadas a catéter venoso central siguen constituyendo una de las complicaciones más importantes. Dentro de las estrategias para la prevención o el tratamiento de estas infecciones se encuentra el empleo de sellados con antisépticos, como el etanol o la taurolidina, o de antibióticos...
July 19, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Nur Efe İris, Taner Yıldırmak, Habip Gedik, Funda Şimşek, Demet Aydın, Naciye Demirel, Osman Yokuş
OBJECTIVE: The aim of this study is to investigate if neutrophil CD64 expression in febrile neutropenia patients could be used as an early indicator of bacteriemia. PATIENTS-METHODS: All consecutive patients, older than 18 years of age and developed febrile neutropenia episodes due to hematological malignancies from February 2013-to July 2013 at the hematology department of Okmeydanı Training and Research Hospital, Istanbul, Turkey were included into the study...
June 27, 2016: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
C Ferré, F Llopis, J Jacob
OBJECTIVE: The aim of the study was to analyze the characteristics of patients with acute prostatitis presenting to the Emergency Department, the microbiological findings, antibiotic susceptibility, and bacteraemia associated factors. METHODS: Observational and cohort study with prospective follow-up including patients with acute prostatitis presenting to the Emergency Department from January-December 2012. Data were collected for demographic variables, comorbidities, microbiological findings, antibiotic treatment and outcome...
August 2016: Revista Española de Quimioterapia: Publicación Oficial de la Sociedad Española de Quimioterapia
X Nuvials, M Palomar, F Alvarez-Lerma, P Olaechea, S Otero, S Uriona, M Catalán, R Gimeno, M P Gracia, I Seijas
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
Lidiane Miotto Barretta, Lúcia Marinilza Beccaria, Cláudia Bernardi Cesarino, Maria Helena Pinto
OBJECTIVE: to identify the model, average length of stay on site and complications of central venous catheter in patients undergoing transplant of hematopoietic stem cells and verify the corresponding relationship between the variables: age, gender, medical diagnosis, type of transplant, implanted catheter and insertion site. METHOD: a retrospective and quantitative study with a sample of 188 patients transplanted records between 2007 and 2011. RESULTS: the majority of patients used Hickman catheter with an average length of stay on site of 47...
June 7, 2016: Revista Latino-americana de Enfermagem
N V Anisimov, A A Kislichkina, M E Platonov, V V Evseeva, L A Kadnikova, N A Lipatnikova, A G Bogun, S V Dentovskaya, A P Anisimov
The attempt to combine Yersinia pseudotuberculosis and Yersinia pestis into one species has been unsupported by microbiologists due to the specific features of the epidemiology and clinical presentations of their induced diseases and to basic differences in their virulence. Pseudotuberculosis is predominantly a relatively mild human intestinal infection transmitted through contaminated food and plague is an acute generalized disease with high mortality, which is most frequently transmitted by the bites of infected fleas...
January 2016: Meditsinskaia Parazitologiia i Parazitarnye Bolezni
N Mémain, M Ben M'Rad, P Rouvier, J-L Pallot
INTRODUCTION: Intestinal symptoms (cramping, flatulence) and iron deficient anemia are classical presenting manifestations of duodenal hookworm infestation in patients living in endemic area. CASE REPORT: We report a 45-year-old immunocompetent metropolitan man who presented with intestinal obstruction secondary to massive hookworm infestation complicated by fatal plurimicrobial bacteriemia with refractory septic shock. CONCLUSION: We report a case of acute surgical abdominal presentation with septicemia and refractory shock syndrome due to ileal translocation secondary to massive hookworm infestation...
October 2016: La Revue de Médecine Interne
Cláudia Gomes, Sandra Martinez-Puchol, Maria J Pons, Jorge Bazán, Carmen Tinco, Juana del Valle, Joaquim Ruiz
BACKGROUND: The lack of an effective diagnostic tool for Carrion's disease leads to misdiagnosis, wrong treatments and perpetuation of asymptomatic carriers living in endemic areas. Conventional PCR approaches have been reported as a diagnostic technique. However, the detection limit of these techniques is not clear as well as if its usefulness in low bacteriemia cases. The aim of this study was to evaluate the detection limit of 3 PCR approaches. METHODOLOGY/PRINCIPAL FINDINGS: We determined the detection limit of 3 different PCR approaches: Bartonella-specific 16S rRNA, fla and its genes...
March 2016: PLoS Neglected Tropical Diseases
N S Bagirova
The diagnostic of infections of blood flow using technique of hemofermentation (blood inoculation) is one of the most significant functions of laboratory of clinical microbiology. The effectiveness of the given technique depends on many factors, including criteria of evaluation of clinical significance of episode of bacteriemia and isolated microorganism applied by physician-microbiologist. The intelligent analysis of received results is needed. The physician-microbiologist has to determine if microorganism isolated from given blood sample, is a genuine agent of infections of bloodflow or it is only effect of contamination of analyzed sample at certain stage...
August 2015: Klinicheskaia Laboratornaia Diagnostika
Julián David Martínez, Laura Moya, Geovanny Hernández, Lucia Viola
We present a case report of a patient with spontaneous gastro-splenic fistula due to gastric adenocarcinoma associated with Streptococcus anginosus bacteriemia and fatal outcome.
April 2015: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Gulhan Yagmur, Baris Derya Ercal, Zafer Mengeloglu, Fatma Mutlu Sariguzel, Elife Berk, Derya Saglam
OBJECTIVE: Early detection of antibiotic susceptibility profile of the isolates has critical importance in terms of immediate beginning of the appropriate treatment and increasing of treatment success, such as meningitis, bacteriemia and sepsis. In the present study, it was aimed to compare the antibiotic susceptibility results of Quicolor (Salubris Inc., Massachusetts, USA) and standard disk diffusion method. METHODS: One hundred twenty three isolates were included in this study (80 Enterobacteriaceae, 15 Staphylococci and 28 nonfermentative Gram-negative bacteria)...
March 2015: Pakistan Journal of Medical Sciences Quarterly
A Yalci, Z K Celebi, B Ozbas, O L Sengezer, H Unal, K O Memikoğlu, S Sengul, A Tuzuner, K Keven
Kidney transplantation (KT) is the best available therapy for patients with end-stage renal disease. Infectious complications are a common cause of morbidity and mortality. In this study, we evaluated the risk factors and outcomes of infectious complications in the first year after transplantation. This is a retrospective and observational study of kidney transplant recipients at Ankara University's Ibni Sina Hospital between January 2009 and August 2013. A total of 206 kidney transplant recipients were evaluated...
June 2015: Transplantation Proceedings
F Rivera, B Massutí, M Salcedo, J Sastre, J Martínez Galán, M Valladares-Ayerbes, R Serrano, Ma L García de Paredes, J L Manzano, M Galán, M Alsina, A L Yuste Izquierdo, C López, E Díaz-Rubio, V Conde, M Reboredo, Ma T Cano, V Pachón, E Aranda
PURPOSE: Chemotherapy has improved the overall survival (OS) in patients (pts) with advanced gastric cancer (AGC). Docetaxel (D), oxaliplatin (O) and capecitabine (C) have shown interesting activity in this setting. We defined "suboptimal" pts as those with PS ECOG = 2, weight loss 10-25% and/or age ≥70 years. This population is usually underrepresented in AGC clinical trials. METHODS: We explored in 43 previously untreated "suboptimal" AGC pts the effect of "miniDOX" regimen (D: 40 mg/m(2) iv, day 1; O: 80 mg/m(2) iv, day 1; C: 625 mg/m(2) po bid, day 1 to day 21, every 21 days; after six courses, only C was maintained)...
February 2015: Cancer Chemotherapy and Pharmacology
Claire de Moreuil, Geneviève Héry-Arnaud, Charles-Henri David, Bastien Provost, Philippe Mondine, Zarrin Alavi, Luc de Saint Martin, Eric Bezon, Rozenn Le Berre
Post-sternotomy mediastinitis, a nosocomial infection mostly caused by staphylococci, can be life-threatening. A case of mediastinitis due to Finegoldia magna after a coronary artery bypass graft surgery was reviewed. Although this bacterium is difficult to be isolated from routine blood cultures, a F. magna bacteriemia associated with mediastinitis was diagnosed.
April 2015: Anaerobe
Lara Zafrani, Elie Azoulay
Severe infections in neutropenic patient often progress rapidly leading to life-threatening organ dysfunction requiring admission to the Intensive Care Unit. Management strategies include early adequate appropriate empirical antimicrobial, early admission to ICU to avoid any delay in the diagnostic and therapeutic management of organ dysfunction. This review discusses the main clinical situations encountered in critically ill neutropenic patients. Specific diagnostic and therapeutic approaches have been proposed for acute respiratory failure, shock, neutropenic enterocolitis, catheter-related infections, cellulitis and primary bacteriemia...
November 28, 2014: BMC Infectious Diseases
Hacer Yapıcıoğlu, Ferda Özlü, Yaşar Sertdemir
OBJECTIVE: Neonatal systemic infection is a leading cause of morbidity and mortality both in industrialized and developing countries. The aim of this prospective study was to evaluate if vital signs had a predictive power in neonatal sepsis as an early marker. METHODS: This study was designed as a matched case-control study. Vital signs were monitorized prior to infection in newborns that had healthcare-associated blood stream infection (BSI). Maximum and minimum values of the vital signs (blood pressure, heart rate, respiratory rate and temperature) of the babies at rest were recorded from the nurse observation charts five days prior to clinical sepsis and compared with vital signs of healthy, age-matched babies...
2015: Journal of Maternal-fetal & Neonatal Medicine
A I Sinipal'nikov
The data on the effectiveness of new cephalosporin, ceftaroline, for the treatment of patients with extramural pneumonia in need of hospitalization. They show that the use of ceftaroline for 5-7 days for the treatment of hospitalized patients with extramural pneumococcal pneumonia exceeding standard therapy with ceftriaxone in terms of efficacy. Therapeutic effect of ceftaroline did not depend on S. pneumoniae serotype and persisted in severe cases complicated by bacteriemia. Another advantage of ceftaroline over ceftriaxone is it ensured an adequate response on day 4 of therapy...
2014: Klinicheskaia Meditsina
Francisco Alvarez-Lerma, Glòria Oliva, Joan M Ferrer, Alba Riera, Mercedes Palomar
The nationwide Bacteremia Zero (BZ) Project consists in the simultaneous implementation of measures to prevent central venous catheter-related bacteremia (CVC-B) in critically ill patients and in the development of an integral safety plan. The objective is to present the results obtained after the implementation of the BZ project in the ICUs of the Autonomous Community of Catalonia, Spain. All patients admitted to ICUs in Catalonia participating in the ENVIN-HELICS registry between January 2009 and June 2010 were included...
July 2014: Medicina Clínica
Minh Huynh, Silvia Carnaccini, Todd Driggers, H L Shivaprasad
An 18-yr-old male hyacinth macaw (Anadorhynchus hyacinthinus) was found dead in his aviary with no preexisting signs. The bird had a chronic history of feather damaging behavior, with severe ulcerative dermatitis. Pathologic findings revealed a vegetative valvular endocarditis, myocarditis, septicemia, chronic severe glomerulonephritis, and thyroid dysplasia. Staphylococcus aureus was isolated from the valve, the liver, and the skin. Repeated trauma and low-rate bacteriemia may have contributed to the development of endocarditis...
June 2014: Avian Diseases
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