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Antisepsis

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https://www.readbyqxmd.com/read/29300197/effectiveness-of-sucrose-used-routinely-for-pain-relief-and-neonatal-clinical-risk-in-preterm-infants-a-nonrandomized-study
#1
Beatriz Oliveira Valeri, Cláudia Maria Gaspardo, Francisco Eulógio Martinez, Maria Beatriz Martins Linhares
BACKGROUND: Preterm infants (PI) requiring the Neonatal Intensive Care Unit (NICU) are exposed to early repetitive pain/distress. Little is known about how pain relief strategies interact with infants'clinical health status, such as severity of illness with pain responses. This study aimed to examine main and interactive effects of routine sucrose intervention and neonatal clinical risk (NCR) on biobehavioral pain reactivity-recovery in PI during painful blood collection procedures. METHODS: Very-low birthweight PI (n=104) were assigned to Low and High Clinical Risk Groups, according to the Clinical Risk Index for Babies...
January 3, 2018: Clinical Journal of Pain
https://www.readbyqxmd.com/read/29295779/a-survey-of-international-antisepsis-procedures-for-neuraxial-catheterisation-in-labour
#2
K Fayman, A Allan, C Hudson, M Logarta
BACKGROUND: Neuraxial analgesia during labour is a mainstay of anaesthetic practice globally. Despite the potential for significant neurological and infectious complications, international antisepsis practices for neuraxial anaesthesia vary widely. AIMS: The primary aim of this study was to clarify international antisepsis practices prior to neuraxial analgesia in labour. The secondary aim was to determine an approximate international incidence of neuraxial infections and neurological complications secondary to neuraxial analgesia techniques in labour...
October 6, 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/29283367/surveillance-of-environmental-and-procedural-measures-of-infection-control-in-the-operating-theatre-setting
#3
Laura Dallolio, Alessandra Raggi, Tiziana Sanna, Magda Mazzetti, Alessandra Orsi, Angela Zanni, Patrizia Farruggia, Erica Leoni
The microbiological contamination of operating theatres and the lack of adherence to best practices by surgical staff represent some of the factors affecting Surgical Site Infections (SSIs). The aim of the present study was to assess the microbiological quality of operating settings and the staff compliance to the SSI evidence-based control measures. Ten operating rooms were examined for microbiological contamination of air and surfaces, after cleaning procedures, in "at rest" conditions. Furthermore, 10 surgical operations were monitored to assess staff compliance to the recommended practices...
December 28, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29280365/more-antisepsis-less-antibiotics-whenever-possible
#4
Andrzej Grzybowski, Magdalena Turczynowska
Increasing bacterial resistance to antibiotics has recently become an important medical challenge. In ophthalmology antibiotics are widely used for treatment and prophylaxis of ocular infections. In many cases antiseptics may be a valuable adjunct and sometimes even an alternative to antibiotics for the prevention and treatment of infections, reducing the overuse of antibiotics. This review aims to highlight the available literature on the subject of antibiotic resistance in ophthalmology. Full understanding of this growing problem is necessary for tailoring effective pre-, intra-, and postoperative management to improve antibiotic stewardship programs...
December 27, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29262416/consensus-on-wound-antisepsis-update-2018
#5
Axel Kramer, Joachim Dissemond, Simon Kim, Christian Willy, Dieter Mayer, Roald Papke, Felix Tuchmann, Ojan Assadian
Wound antisepsis has undergone a renaissance due to the introduction of highly effective wound-compatible antimicrobial agents and the spread of multidrug-resistant organisms (MDROs). However, a strict indication must be set for the application of these agents. An infected or critically colonized wound must be treated antiseptically. In addition, systemic antibiotic therapy is required in case the infection spreads. If applied preventively, the Wounds-at-Risk Score allows an assessment of the risk for infection and thus appropriateness of the indication...
December 21, 2017: Skin Pharmacology and Physiology
https://www.readbyqxmd.com/read/29260707/-can-othopaedic-surgeons-accelerate-time-or-does-the-enthusiasm-for-alcohol-rub-just-decrease-by-age
#6
Jakob Klit, Per Hviid Gundtoft, Eske Brand, Peter Toft Tegnberg, Kristoffer Weisskirchner Barfod
Senior surgeons can execute a full surgical hand antisepsis in no time. This could be due to a changed perception of time with age. This cross-sectional study secretly timed orthopaedic surgeons during alcohol rub, investigated their perception of 120 see and attitude towards hand antisepsis. Surgeons under 50 years of age used significantly longer time on alcohol rub. No significant difference in perception of neither time nor attitude towards surgical hand antisepsis were found between age groups. Surgeons are not affected by mental aging but seem to be able to accelerate time...
December 11, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29238663/prevention-identification-and-management-of-post-operative-penile-implant-complications-of-infection-hematoma-and-device-malfunction
#7
REVIEW
Timothy K O'Rourke, Alexander Erbella, Yu Zhang, Matthew S Wosnitzer
Penile prosthesis implant surgery is an effective management approach for a number of urological conditions, including medication refractory erectile dysfunction (ED). Complications encountered post-operatively include infection, bleeding/hematoma, and device malfunction. Since the 1970s, modifications to these devices have reduced complication rates through improvement in antisepsis and design using antibiotic coatings, kink-resistant tubing, lock-out valves to prevent autoinflation, and modified reservoir shapes...
November 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29190159/performance-of-bio-occlusive-dressing-as-barrier-protection-from-presurgical-chlorhexidine-skin-preparation
#8
Frank Brodie, Gregory Bever, David G Hwang
Purpose/Aim of the study: Chlorhexdine has been shown to provide excellent and cost-effective presurgical antisepsis. However, standard presurgical concentrations of chlorhexidine (2-4%) are known to cause ocular injury, even in cases in which a bio-occlusive dressing (Tegaderm™) was applied beforehand to the closed eye. MATERIALS AND METHODS: Three experiments were conducted to assess the barrier performance of Tegaderm™ to chlorhexidine skin prep in vitro and on non-ocular skin...
November 30, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29187930/stages-of-development-of-traditional-simulation-unit-of-surgery-for-manual-extra-capsular-cataract-extraction-in-sub-saharan-african-region
#9
Yannick Bilong, Vikas Mahatme, Ngoune Nanfack, Sapate Santosh, Lucienne Assumpta Bella, Côme Ebana Mvogo
The manual extracapsular extraction of the lens is the surgical technique that is most practiced for the treatment of cataract in sub-Saharan Africa. Learning this technique requires the creation of a surgical simulation unit within training institutes. We describe the development stages of a traditional simulation unit. For this purpose, we present a description of four steps involved in the development of a simulation unit for cataract surgery: the physical creation of the room, the aseptic and antisepsis conditions, the management of the eyes, the development of a curriculum and the administrative policies...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/29185601/adherence-to-central-venous-catheter-insertion-bundle-in-neonatal-and-pediatric-units
#10
Fernanda Lopes de Araújo, Bruna Figueiredo Manzo, Anna Caroline Leite Costa, Allana Dos Reis Corrêa, Juliana de Oliveira Marcatto, Delma Aurélia da Silva Simão
OBJECTIVE: To describe the observed behavior of professionals in two neonatal and pediatric intensive care units regarding the use of central venous catheter insertion bundle, and the clinical and birth profile of neonates and children who received the devices. METHOD: A quantitative descriptive exploratory study was conducted in two intensive care units of a public hospital in Belo Horizonte with neonates and children, between February and September 2016. RESULTS: The sample consisted of 59 observed implants of central venous catheter...
November 27, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/29171793/preoperative-skin-antisepsis-with-chlorhexidine-gluconate-versus-povidone-iodine-a-prospective-analysis-of-6959-consecutive-spinal-surgery-patients
#11
George M Ghobrial, Michael Y Wang, Barth A Green, Howard B Levene, Glen Manzano, Steven Vanni, Robert M Starke, George Jimsheleishvili, Kenneth M Crandall, Marina Dididze, Allan D Levi
OBJECTIVE The aim of this study was to determine the efficacy of 2 common preoperative surgical skin antiseptic agents, ChloraPrep and Betadine, in the reduction of postoperative surgical site infection (SSI) in spinal surgery procedures. METHODS Two preoperative surgical skin antiseptic agents-ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol) and Betadine (7.5% povidone-iodine solution)-were prospectively compared across 2 consecutive time periods for all consecutive adult neurosurgical spine patients...
November 24, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29148002/targeting-zero-catheter-related-bloodstream-infections-in-pediatric-intensive-care-unit-a-retrospective-matched-case-control-study
#12
Daniele G Biasucci, Mauro Pittiruti, Alessandra Taddei, Enzo Picconi, Alessandro Pizza, Davide Celentano, Marco Piastra, Giancarlo Scoppettuolo, Giorgio Conti
INTRODUCTION: The aim of this study was to evaluate the effectiveness and safety of a new three-component 'bundle' for insertion and management of centrally inserted central catheters (CICCs), designed to minimize catheter-related bloodstream infections (CRBSIs) in critically ill children. METHODS: Our 'bundle' has three components: insertion, management, and education. Insertion and management recommendations include: skin antisepsis with 2% chlorhexidine; maximal barrier precautions; ultrasound-guided venipuncture; tunneling of the catheter when a long indwelling time is expected; glue on the exit site; sutureless securement; use of transparent dressing; chlorhexidine sponge dressing on the 7th day; neutral displacement needle-free connectors...
November 8, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/29081301/shortening-the-application-time-of-alcohol-based-hand-rubs-to-15-seconds-may-improve-the-frequency-of-hand-antisepsis-actions-in-a-neonatal-intensive-care-unit
#13
Axel Kramer, Didier Pittet, Romana Klasinc, Stefan Krebs, Torsten Koburger, Christoph Fusch, Ojan Assadian
BACKGROUND For alcohol-based hand rubs, the currently recommended application time of 30 seconds is longer than the actual time spent in clinical practice. We investigated whether a shorter application time of 15 seconds is microbiologically safe in neonatal intensive care and may positively influence compliance with the frequency of hand antisepsis actions. METHODS We conducted in vitro experiments to determine the antimicrobial efficacy of hand rubs within 15 seconds, followed by clinical observations to assess the effect of a shortened hand antisepsis procedure under clinical conditions in a neonatal intensive care unit (NICU)...
October 30, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29061869/infection-prevention-and-control-in-pediatric-ambulatory-settings
#14
REVIEW
Mobeen H Rathore, Mary Anne Jackson
Since the American Academy of Pediatrics published its statement titled "Infection Prevention and Control in Pediatric Ambulatory Settings" in 2007, there have been significant changes that prompted this updated statement. Infection prevention and control is an integral part of pediatric practice in ambulatory medical settings as well as in hospitals. Infection prevention and control practices should begin at the time the ambulatory visit is scheduled. All health care personnel should be educated regarding the routes of transmission and techniques used to prevent the transmission of infectious agents...
November 2017: Pediatrics
https://www.readbyqxmd.com/read/29061748/in-vitro-evaluation-of-povidone-iodine-and-chlorhexidine-against-outbreak-and-non-outbreak-strains-of-mycobacterium-abscessus-using-standard-quantitative-suspension-and-carrier-testing
#15
Aristine Cheng, Hsin-Yun Sun, Yi-Tzu Tsai, Un-In Wu, Yu-Chung Chuang, Jann-Tay Wang, Wang-Huei Sheng, Po-Ren Hsueh, Yee-Chun Chen, Shan-Chwen Chang
BackgroundPovidone-iodine (PI) and chlorhexidine (CHX) are widely used antiseptics active against conventional Staphylococcus aureus, Enterobacteriaceae, Candida species and viruses but their efficacy against Mycobacterium abscessus remain unproven.MethodsWe determined the in vitro potency of alcoholic PI and CHX against M. abscessus subspecies abscessus (ATCC 19977), M. abscessus subspecies bolletii (BCRC 16915), our outbreak strain of M. abscessus subspecies massiliense (TPE 101) in reference to Staphylococcus aureus (ATCC 29213) by standard quantitative suspension and carrier methods (EN 14563)...
October 23, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29019097/efficacy-of-conventional-and-liposomal-povidone-iodine-in-infected-mesh-skin-grafts-an-exploratory-study
#16
Peter M Vogt, Joerg Hauser, Stefan Mueller, Bjoern Bosse, Michael Hopp
INTRODUCTION: Infection is a major threat to wound healing and a leading cause of graft loss in patients undergoing meshed skin grafts (MSGs). Therefore, topical antisepsis is important in the overall treatment scheme. METHODS: An exploratory satellite group of 14 patients with infected MSGs were enrolled as part of a prospective, randomized, controlled, parallel-group, open-label, pilot Phase II study that investigated the efficacy and tolerability of 3% liposomal povidone-iodine hydrogel (PVP-ILH, Repithel(®); RepiGel(®)) versus chlorhexidine gauze in non-infected MSGs...
October 10, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/28972422/a-pioneer-in-two-worlds-thomas-keith-1827-1895-photographer-and-surgeon
#17
Iain Macintyre
Thomas Keith, an Edinburgh surgeon, was an early and successful exponent of the operation of ovariotomy (ovarian cystectomy). He published detailed accounts of all of the patients on whom he carried out this procedure and his published success rate proved to be amongst the best in the world. The leading American surgeon J Marion Sims, who visited Keith to determine the reasons for this success, concluded that Keith's achievement resulted from meticulous attention to detail and his emphasis on the cleanliness of the instruments and the operating field, before this was generally adopted...
January 1, 2017: Journal of Medical Biography
https://www.readbyqxmd.com/read/28967509/skin-antisepsis-with-0-05-sodium-hypochlorite-before-central-venous-catheter-insertion-in-neonates-a-2-year-single-center-experience
#18
Matilde Ciccia, Roksana Chakrokh, Dario Molinazzi, Angela Zanni, Patrizia Farruggia, Fabrizio Sandri
AIM: The study reports a 2-year single-center experience of the practice of skin antisepsis using a 0.05% sodium hypochlorite solution before central venous catheter placement in neonates. METHODS: Eligible subjects included any hospitalized neonate who needed a central line for at least 48 hours. Infants were excluded if they had a generalized or localized skin disorder. An ad hoc Excel (Microsoft Corp, Redmond, WA) file was used to record the data from each patient...
September 26, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28963158/antisepsis-of-the-skin-before-spinal-surgery-with-povidone-iodine-alcohol-followed-by-chlorhexidine-gluconate-alcohol-versus-povidone-iodine-alcohol-applied-twice-for-the-prevention-of-contamination-of-the-wound-by-bacteria-a-randomised-controlled-trial
#19
RANDOMIZED CONTROLLED TRIAL
S Patrick, A McDowell, A Lee, A Frau, U Martin, E Gardner, G McLorinan, N Eames
AIMS: The aim of this study was to determine whether the sequential application of povidone iodine-alcohol (PVI) followed by chlorhexidine gluconate-alcohol (CHG) would reduce surgical wound contamination to a greater extent than PVI applied twice in patients undergoing spinal surgery. PATIENTS AND METHODS: A single-centre, interventional, two arm, parallel group randomised controlled trial was undertaken, involving 407 patients who underwent elective spinal surgery...
October 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28948926/who-s-recommendation-for-surgical-skin-antisepsis-is-premature-authors-reply
#20
Benedetta Allegranzi, Matthias Egger, Didier Pittet, Peter Bischoff, Peter Nthumba, Joseph Solomkin
No abstract text is available yet for this article.
October 2017: Lancet Infectious Diseases
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