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https://www.readbyqxmd.com/read/27903639/automated-classification-of-pain-perception-using-high-density-electroencephalography-data
#1
Gaurav Misra, Wei-En Wang, Derek B Archer, Arnab Roy, Stephen A Coombes
Translating brief millisecond-long pain-eliciting stimuli to the subjective perception of pain is associated with changes in theta, alpha, beta, and gamma oscillations over sensorimotor cortex. However, when a pain-eliciting stimulus continues for minutes, regions beyond the sensorimotor cortex such as the prefrontal cortex are also engaged. Abnormalities in prefrontal cortex have been associated with chronic pain states, but conventional millisecond-long EEG paradigms do not engage prefrontal regions. In the current study we collected high-density EEG data during an experimental paradigm in which subjects experienced a 4 second low or high intensity pain-eliciting stimulus...
November 30, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/27902539/cystoid-macular-edema-and-cystoid-macular-degeneration-as-a-result-of-multiple-pathogenic-factors-in-the-setting-of-central-serous-chorioretinopathy
#2
Polina Astroz, Chandrakumar Balaratnasingam, Lawrence A Yannuzzi
PURPOSE: To report the pathogenic factors that account for cystoid macular edema and cystoid macular degeneration in chronic central serous chorioretinopathy (CSC). METHODS: The clinical course and multimodal imaging findings, including fundus color photography, fundus autofluorescence, spectral-domain optical coherence tomography, and fluorescein angiography, of one eye with cystoid macular edema due to chronic CSC was documented. RESULTS: A 44-year old woman with a history of chronic CSC presented with progressive visual decline in the right eye...
November 29, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27901277/negative-pressure-wound-therapy-for-prevention-and-treatment-of-surgical-site-infections-after-vascular-surgery
#3
REVIEW
S Acosta, M Björck, A Wanhainen
BACKGROUND: Indications for negative-pressure wound therapy (NPWT) in vascular surgical patients are expanding. The aim of this review was to outline the evidence for NPWT on open and closed wounds. METHODS: A PubMed, EMBASE and Cochrane Library search from 2007 to June 2016 was performed combining the medical subject headings terms 'wound infection', 'abdominal aortic aneurysm (AAA)', 'fasciotomy', 'vascular surgery' and 'NPWT' or 'VAC'. RESULTS: NPWT of open infected groin wounds was associated with shorter duration of wound healing by 47 days, and was more cost-effective than alginate dressings in one RCT...
November 30, 2016: British Journal of Surgery
https://www.readbyqxmd.com/read/27900703/the-treatment-of-distal-third-humeral-diaphyseal-fractures-is-there-still-a-place-for-the-external-fixation
#4
N Tartaglia, G Vicenti, M Carrozzo, A Abate, F Rifino, G Picca, G Solarino, B Moretti
INTRODUCTION: The treatment for humeral diaphyseal fractures is still controversial. The purpose of this study was to evaluate the clinical and radiographic outcomes of treating humeral distal third diaphyseal fractures by using external fixation technique. MATERIALS AND METHODS: We retrospectively review 65 cases of diaphyseal humeral fractures (31 type A, 23 type B and 11 type C of the AO/OTA classification) treated with external fixation (Orthofix FAD small) between 2008 and 2013...
December 2016: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/27899318/new-wrinkling-substrate-assay-reveals-traction-force-fields-of-leader-and-follower-cells-undergoing-collective-migration
#5
Sho Yokoyama, Tsubasa S Matsui, Shinji Deguchi
Physical forces play crucial roles in coordinating collective migration of epithelial cells, but details of such force-related phenomena remain unclear partly due to the lack of robust methodologies to probe the underlying force fields. Here we develop a method for fabricating silicone substrates that detect cellular traction forces with a high sensitivity. Specifically, a silicone elastomer is exposed to oxygen plasma under heating. Removal of the heat shrinks the substrate so as to reduce its critical buckling strain in a spatially uniform manner...
November 26, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27898550/severe-intraoperative-shock-related-to-mesenteric-traction-syndrome
#6
Alfredo Haack Couto, Hugo Siqueira, Pablo Pulcheira Brasileiro, Ismar Lima Cavalcanti, Rogério Luiz da Rocha Videira
Mesenteric traction syndrome is defined as arterial hypotension, facial flushing, and tachycardia related to mesenteric traction. We describe a case of mesenteric traction syndrome refractory to catecholamine and vasopressin infusions. The patient, who had Crohn disease, developed severe distributive shock after mesenteric traction while undergoing resection of an intestinal inflammatory mass, accompanied by facial flushing and unaltered readings for pulse oximetry, capnography, and bispectral index monitoring...
November 28, 2016: A & A Case Reports
https://www.readbyqxmd.com/read/27898445/pathologic-myopia
#7
Kyoko Ohno-Matsui
Pathologic myopia (PM) is the only myopia that causes the loss of best-corrected visual acuity. The main reason for best-corrected visual acuity loss is complications specific to PM, such as myopic maculopathy, myopic traction maculopathy, and myopic optic neuropathy (or glaucoma). The meta-analyses of the PM study group (META-PM study) made a classification system for myopic maculopathy. On the basis of this study, PM has been defined as eyes having atrophic changes equal to or more severe than diffuse atrophy...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27897027/-acute-uterine-inversion-after-delivery
#8
E Pechová, I Bydžovská, M Krausová, M Lubušký
OBJECTIVE: A case of acute inversion of the uterus after childbirth, in which we successfully perform a manual vaginal reposition of the uterus. DESIGN: Case report. SETTING: Department of Obstetrics and Gynaecology, Krajská nemocnice Liberec, a.s.; Department of Obstetrics and Gynaecology, Palacky University Hospital, Olomouc. OBSERVATION: Our case report describes acute post-partum uterine inversion of the second degree, which developed after delivery in a 36-year-old primigravida...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27896435/course-of-pelvic-lift-during-total-hip-arthroplasty
#9
Steffen Brodt, Dimitri Nowack, Linda Krakow, Christoph Windisch, Georg Matziolis
INTRODUCTION: The position of the cup makes a major contribution to the success of total hip arthroplasty (THA). In conventional implantation of the prosthesis without navigation, the surgeon relies on the spatial position of the pelvis. However, iatrogenic manipulation of the pelvis during different surgical steps constantly changes the position of the pelvis during the operation. The position of the pelvis is substantial for the correct placement of the cup. The objective of this study was to investigate and visualize the course of this pelvic lift and correlate it to certain surgical steps...
November 28, 2016: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/27896274/halo-gravity-traction-is-associated-with-reduced-bone-mineral-density-of-patients-with-severe-kyphoscoliosis
#10
Xiao Han, Weixiang Sun, Yong Qiu, Leilei Xu, Shifu Sha, Benlong Shi, Huang Yan, Zhen Liu, Zezhang Zhu
Background. Halo gravity traction (HGT) is one of the most commonly used perioperative techniques for the treatment of severe kyphoscoliosis. This study was to explore the influence of HGT on the BMD of these patients. Methods. Patients with severe kyphoscoliosis treated by preoperative HGT for at least 2 months were included. Patients' BMD were assessed by dual-energy X-ray absorptiometry at lumbar spine (LS, L2-L4) and femur neck (FN) of the nondominant side. The weight and duration of traction, as well as baseline characteristics, were recorded...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27896060/diffuse-bronchiectasis-as-the-primary-manifestation-of-endobronchial-sarcoidosis
#11
Paul D Hiles, Kenneth R Kemp, Jean M Coviello
Sarcoidosis is an idiopathic disease that most commonly involves the lungs and is characterized by granulomatous inflammation. Bronchiectasis is one pulmonary manifestation of sarcoidosis, although it is almost always observed as traction bronchiectasis in the setting of fibrotic lung disease. A 50-year-old woman was evaluated for chronic cough and bronchiectasis with a small amount of peripheral upper lobe honeycombing and no significant pulmonary fibrosis or lymphadenopathy. After an extensive laboratory and imaging evaluation did not identify a cause of her bronchiectasis, bronchoscopy was performed to assess for primary ciliary dyskinesia and revealed a diffuse cobblestone appearance of the airway mucosa...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27896018/development-and-preliminary-results-of-bimanual-smart-micro-surgical-system-using-a-ball-lens-coupled-oct-distance-sensor
#12
Dongwoo Koo, Hyun-Cheol Park, Peter L Gehlbach, Cheol Song
Bimanual surgery enhances surgical effectiveness and is required to successfully accomplish complex microsurgical tasks. The essential advantage is the ability to simultaneously grasp tissue with one hand to provide counter traction or exposure, while dissecting with the other. Towards enhancing the precision and safety of bimanual microsurgery we present a bimanual SMART micro-surgical system for a preliminary ex-vivo study. To the best of our knowledge, this is the first demonstration of a handheld bimanual microsurgical system...
November 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27893549/how-deleterious-is-facial-nerve-dissection-for-the-facial-nerve-in-parotid-surgery-an-electrophysiological-evaluation
#13
Sabri Baki Eren, Remzi Dogan, Orhan Ozturan, Bayram Veyseller, Ayşenur Meriç Hafiz
OBJECTIVE: This study was conducted to investigate subclinical electrophysiological deleterious effect due to microtrauma to the nerve in response to the dissection of a tumor and parotid tissue from the facial nerve and its branches and surgical traction experienced during the operation. METHODS: The study included 34 adult patients who underwent parotidectomy operations under intraoperative facial nerve monitoring. Three measurements were taken from each patient to evaluate facial nerve functions, with 3 stimuli of different intensities applied with different timing...
November 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27892536/investigation-of-cell-substrate-adhesion-properties-of-living-chondrocyte-by-measuring-adhesive-shear-force-and-detachment-using-afm-and-inverse-fea
#14
Trung Dung Nguyen, YuanTong Gu
It is well-known that cell adhesion is important in many biological processes such as cell migration and proliferation. A better understanding of the cell adhesion process will shed insight into these cellular biological responses as well as cell adhesion-related diseases treatment. However, there is little research which has attempted to investigate the process of cell adhesion and its mechanism. Thus, this paper aims to study the time-dependent adhesion properties of single living chondrocytes using an advanced coupled experimental-numerical approach...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27886856/a-retrospective-cohort-study-of-outcome-in-systemic-sclerosis-associated-interstitial-lung-disease
#15
Masaki Okamoto, Kiminori Fujimoto, Junko Sadohara, Kiyomi Furuya, Shinjiro Kaieda, Tomoya Miyamura, Eiichi Suematsu, Yasuhiko Kitasato, Tomotaka Kawayama, Hiroaki Ida, Masao Ichiki, Tomoaki Hoshino
BACKGROUND: The relationship between the histological pattern and survival in systemic sclerosis-associated interstitial lung disease (SSc-ILD) is unclear. In patients with SSc-ILD, we investigated whether the clinical data obtained by non-invasive examinations could be used for prognostic evaluation, and attempted to clarify whether complicating acute exacerbation (AE) and the selection of pharmacological therapy were associated with survival. METHODS: Thirty-five patients with SSc-ILD, who had not been diagnosed by surgical lung biopsy were analyzed, retrospectively...
November 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27886836/ulnar-neuropathy-in-cyclists
#16
REVIEW
Jacob W Brubacher, Fraser J Leversedge
The form and function of the cyclist exposes the ulnar nerve to both traction and compressive forces at both the elbow and wrist. Prevention of ulnar neuropathy and treatment of early symptoms include bike fitting, avoidance of excessive or prolonged weight-bearing through the hands, and the use of padded gloves. For persisting or progressive symptoms, a thorough history and physical examination is essential to confirm the diagnosis and to rule out other sites of nerve compression. The majority of compression neuropathies in cyclists resolve after appropriate rest and conservative treatment; however, should symptoms persist, nerve decompression may be indicated...
February 2017: Hand Clinics
https://www.readbyqxmd.com/read/27876376/non-surgical-and-surgical-interventions-for-airway-obstruction-in-children-with-robin-sequence
#17
Manouk J S van Lieshout, Koen F M Joosten, Irene M J Mathijssen, Maarten J Koudstaal, Eppo B Wolvius, Marc P van der Schroeff
There is widespread lack of consensus regarding treatment of airway obstruction in children with Robin Sequence. This study aimed to systematically summarize outcomes of non-surgical and surgical options to treat airway obstruction in children with Robin Sequence. The authors searched the Medline, EMBASE and CENTRAL databases. Studies primarily on mandibular distraction were excluded. Study quality was appraised with the Methodological Index for Non-Randomized Studies (MINORS) score. Forty-eight studies were included, of which 45 studies had a retrospective non-comparative set up, two studies had a prospective design and one study was a clinical trial...
July 2, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27876024/evaluation-of-computer-based-computer-tomography-stratification-against-outcome-models-in-connective-tissue-disease-related-interstitial-lung-disease-a-patient-outcome-study
#18
Joseph Jacob, Brian J Bartholmai, Srinivasan Rajagopalan, Anne Laure Brun, Ryoko Egashira, Ronald Karwoski, Maria Kokosi, Athol U Wells, David M Hansell
BACKGROUND: To evaluate computer-based computer tomography (CT) analysis (CALIPER) against visual CT scoring and pulmonary function tests (PFTs) when predicting mortality in patients with connective tissue disease-related interstitial lung disease (CTD-ILD). To identify outcome differences between distinct CTD-ILD groups derived following automated stratification of CALIPER variables. METHODS: A total of 203 consecutive patients with assorted CTD-ILDs had CT parenchymal patterns evaluated by CALIPER and visual CT scoring: honeycombing, reticular pattern, ground glass opacities, pulmonary vessel volume, emphysema, and traction bronchiectasis...
November 23, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27875095/routine-bronchoscopy-and-fogarty-catheter-occlusion-of-tracheoesophageal-fistulas
#19
Victoria K Pepper, Laura A Boomer, Arlyne K Thung, Jonathan M Grischkan, Karen A Diefenbach
INTRODUCTION: Use of a Fogarty catheter for emergent occlusion of tracheoesophageal fistulas (TEFs) has been described for use in unstable neonates. Our purpose was to describe a case series of elective Fogarty catheter occlusion of the TEF. MATERIALS AND METHODS: A formal operative laryngoscopy and rigid bronchoscopy were performed with Fogarty catheter placement into the fistula before surgical intervention. The balloon was inflated and gentle traction provided occlusion of the tract...
November 22, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27872289/fibrous-nonlinear-elasticity-enables-positive-mechanical-feedback-between-cells-and-ecms
#20
Matthew S Hall, Farid Alisafaei, Ehsan Ban, Xinzeng Feng, Chung-Yuen Hui, Vivek B Shenoy, Mingming Wu
In native states, animal cells of many types are supported by a fibrous network that forms the main structural component of the ECM. Mechanical interactions between cells and the 3D ECM critically regulate cell function, including growth and migration. However, the physical mechanism that governs the cell interaction with fibrous 3D ECM is still not known. In this article, we present single-cell traction force measurements using breast tumor cells embedded within 3D collagen matrices. We recreate the breast tumor mechanical environment by controlling the microstructure and density of type I collagen matrices...
November 21, 2016: Proceedings of the National Academy of Sciences of the United States of America
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