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https://www.readbyqxmd.com/read/28917408/refractive-outcome-comparison-between-vitreomacular-interface-disorders-after-phacovitrectomy
#1
Zeynep Eylül Ercan, İmren Akkoyun, Eylem Yaman Pınarcı, Gürsel Yılmaz, Hülya Topçu
PURPOSE: To compare the refractive accuracy of intraocular lens (IOL) power calculations between patients with vitreomacular interface disorders who had phacovitrectomy for vitreomacular traction (VMT), epiretinal membranes (ERM), and macular holes. SETTING: Baskent University Department of Ophthalmology, Ankara, Turkey. DESIGN: Retrospective case series. METHODS: Refraction results 8 weeks postoperatively were compared between phacovitrectomy (3 study groups comprising eyes with VMT with intrafoveal pseudocysts, ERM, or medium-to-large macular holes) and phacoemulsification (control group comprising eyes having phacoemulsification only)...
August 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28917092/progressive-halo-vest-traction-preceding-posterior-occipitocervical-instrumented-fusion-for-irreducible-atlantoaxial-dislocation-and-basilar-invagination
#2
Peng Li, Deming Bao, Huijuan Cheng, Fanshuai Meng, Junwei Li
OBJECTIVES: Surgical treatment of irreducible atlantoaxial dislocation (IAAD) with basilar invagination (BI) is associated with high rates of severe complications, including mortality. This retrospective study investigated the safety and efficacy of progressive halo-vest traction for IAAD with BI prior to posterior occipitocervical instrumented fusion. PATIENTS AND METHODS: Between 2009 and 2013, 39 patients with IAAD with BI underwent preoperative reduction by progressive halo-vest traction for 20...
September 5, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28915383/force-activatable-biosensor-enables-single-platelet-force-mapping-directly-by-fluorescence-imaging
#3
Yongliang Wang, Dana N LeVine, Margaret Gannon, Yuanchang Zhao, Anwesha Sarkar, Bailey Hoch, Xuefeng Wang
Integrin-transmitted cellular forces are critical for platelet adhesion, activation, aggregation and contraction during hemostasis and thrombosis. Measuring and mapping single platelet forces are desired in both research and clinical applications. Conventional force-to-strain based cell traction force microscopies have low resolution which is not ideal for cellular force mapping in small platelets. To enable platelet force mapping with submicron resolution, we developed a force-activatable biosensor named integrative tension sensor (ITS) which directly converts molecular tensions to fluorescent signals, therefore enabling cellular force mapping directly by fluorescence imaging...
September 8, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28915035/photoelectrochemistry-of-photosystem-ii-in-vitro-vs-in-vivo
#4
Jenny Z Zhang, Paolo Bombelli, Katarzyna P Sokol, Andrea Fantuzzi, A William Rutherford, Christopher J Howe, Erwin Reisner
Factors governing the photoelectrochemical output of photosynthetic microorganisms are poorly understood, which can lead to energy losses through inefficient electron transfer (ET) processes. Here, we systematically compare the photoe-lectrochemistry of photosystem II (PSII) protein-films to cyano-bacteria biofilms to derive: (i) the losses in light-to-charge con-version efficiencies, (ii) gains in photocatalytic longevity, and (iii) insights into the ET mechanism at the biofilm interface. This study was enabled by the use of hierarchically structured elec-trodes, which could be tailored for high/stable loadings of PSII core complexes and Synechocystis sp...
September 15, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28912520/intraoperative-intorsional-traction-test-of-the-inferior-oblique
#5
A J Connor, S P Kraft
PurposeWe present a novel variation of the traction test of the inferior oblique (IO) muscle. We demonstrate the correlation between the traction test and clinically graded IO overaction and describe the utility of this test to confirm IO weakening.MethodsWe performed a retrospective chart review on all patients who underwent IO surgery and intraoperative intorsion traction tests by a single surgeon over a 10-year period. We compared the traction test results, in 'clock hours' of freedom, before and after IO surgery...
September 15, 2017: Eye
https://www.readbyqxmd.com/read/28905839/postvitrectomy-macular-hole-undergoing-delayed-closure-after-28-months
#6
Rutul Patel, Mahesh Gopalakrishnan, Bindu Rajesh, Anantharaman Giridhar
Case report of a 70-year-old male who developed full thickness macular hole (MH) following vitrectomy for vitreomacular traction syndrome. The further intervention was deferred due to the unwillingness of the patient for the second surgery. Periodic follow up of the patient, revealed improvement in visual acuity with the closure of the MH after 28 months.
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905829/variation-in-the-vitreoretinal-configuration-of-stage-4-retinopathy-of-prematurity-in-photocoagulated-and-treatment-naive-eyes-undergoing-vitrectomy
#7
Salil Sharad Gadkari, Madan Deshpande
PURPOSE: We sought to document the difference in the vitreoretinal configuration of Stage 4 retinopathy of prematurity (ROP) in photocoagulated and treatment naive eyes undergoing vitrectomy and to correlate it with surgical complexity. METHODS: Consecutive eyes posted for vitrectomy with Stage 4 ROP were documented preoperatively using a RetCam for the presence of peripheral traction (PT), presence of central traction just outside the arcades, and presence of traction extending to the lens...
September 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28905110/-indications-and-technique-for-transconjunctival-optic-nerve-sheath-fenestration-video-article
#8
REVIEW
W A Lagrèze, N Gross, J Biermann, L Joachimsen
BACKGROUND: Placement of a ventricular shunt is the primary surgical procedure for lowering intracranial pressure in pseudotumor cerebri syndrome; however, if ophthalmological symptoms prevail over neurological symptoms or if there are no neurological symptoms at all, optic nerve sheath fenestration may be a valuable option for relief of pressure on the retrobulbar optic nerve when papilledema caused by pseudotumor cerebri syndrome threatens vision despite previous conservative measures...
September 13, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28904897/peyronie-s-graft-surgery-tips-and-tricks-from-the-masters-in-andrologic-surgery
#9
Georgios Hatzichristodoulou, Peter Tsambarlis, Hubert Kübler, Laurence A Levine
BACKGROUND: Grafting techniques in the surgical management of Peyronie's disease (PD) are challenging, especially in inexperienced hands. In order to improve surgical outcomes the urologist should follow a standard surgical approach, preferably of an established and reliable grafting technique. The aim of this study is to provide tips and tricks for graft surgery for PD. METHODS: This report offers a step-by-step tutorial for grafting techniques in PD, especially for the Sealing technique and the partial plaque excision and grafting (PEG) procedure...
August 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28903319/loss-of-giant-obscurins-alters-breast-epithelial-cell-mechanosensing-of-matrix-stiffness
#10
Kimberly M Stroka, Bin Sheng Wong, Marey Shriver, Jude M Phillip, Denis Wirtz, Aikaterini Kontrogianni-Konstantopoulos, Konstantinos Konstantopoulos
Obscurins are a family of RhoGEF-containing proteins with tumor and metastasis suppressing roles in breast epithelium. Downregulation of giant obscurins in normal breast epithelial cells leads to reduced levels of active RhoA and of its downstream effectors. Herein, we elucidate how depletion of giant obscurins affects the response of breast epithelial cells to changes in the mechanical properties of the microenvironment. We find that knockdown of obscurins increases cell morphodynamics, migration speed, and diffusivity on polyacrylamide gels of ≥ 1 kPa, presumably by decreasing focal adhesion area and density as well as cell traction forces...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28902255/taking-advantage-of-an-unerupted-third-molar-a-case-report
#11
Igor Figueiredo Pereira, Fernando Zander Mucci Santiago, Augusto Cesar Sette-Dias, Vladimir Reimar Augusto de Souza Noronha
Introduction: Treatments with dental surgery seek to displace tooth to the correct position within the dental arch. Objective: To report a clinical case that took advantage of an unerupted third molar. Case history: A male patient, 18 years of age, was referred by his dentist to evaluate the third molars. The clinical exam revealed no visible lower third molars. The computed tomography (CT) exam showed the presence of a supernumerary tooth in the region of the mandibular ramus, on the left side, and impaction of the third molar, which was causing root resorption on the second molar, thus making it impossible to remain in the buccal cavity...
July 2017: Dental Press Journal of Orthodontics
https://www.readbyqxmd.com/read/28902070/contending-with-preplanned-death-questions-for-clinicians
#12
Joel Yager
BACKGROUND AND OBJECTIVES: The goal of this column is to assist readers in reflecting on their attitudes and responses toward clinical and nonclinical situations involving preplanned deaths by decisionally capable individuals. Such circumstances range from encountering individuals in one's personal and professional lives who desire and intend to end their lives under their own terms, to having such individuals request assistance with predeath and postdeath arrangements. METHODS: Attending to pertinent literature, this essay uses Socratic inquiry to question conventional assumptions and attitudes, push readers' thoughts beyond typical comfort zones, and consider alternative modes of responding to challenges posed by preplanned death...
September 8, 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28895824/value-based-care-will-flop-without-clinical-integration
#13
Chad Johnson
Value-based payment is gaining traction and proving to be a major factor in health care reform. But the success of those value-based models will depend on true clinical integration of providers-not just lip service to coordination.
August 2017: Managed Care
https://www.readbyqxmd.com/read/28895441/successful-placement-of-a-baha-implant-in-a-patient-with-epidermolysis-bullosa-a-case-report-and-review-of-the-literature
#14
Jason R Brown, D Micah Milgraum, Farhaad R Riyaz, Marla N Jahnke, Prasad John Thottam
INTRODUCTION: Epidermolysis bullosa (EB) is a spectrum of mechanobullous disorders characterized by blistering following minor trauma or traction to the skin. Hearing loss in this population is poorly described in the otolaryngology literature, and its treatment oftentimes results in external auditory canal skin irritation. CASE PRESENTATION: We present the case of a 26-year-old female with EB and mixed hearing loss unable to wear conventional hearing aids due to sequelae of the external auditory canals...
September 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28893211/clinical-performance-and-patient-outcome-after-simulation-based-training-in-prevention-and-management-of-postpartum-haemorrhage-an-educational-intervention-study-in-a-low-resource-setting
#15
Ellen Nelissen, Hege Ersdal, Estomih Mduma, Bjørg Evjen-Olsen, Jos Twisk, Jacqueline Broerse, Jos van Roosmalen, Jelle Stekelenburg
BACKGROUND: Postpartum haemorrhage (PPH) is a major cause of maternal mortality. Prevention and adequate treatment are therefore important. However, most births in low-resource settings are not attended by skilled providers, and knowledge and skills of healthcare workers that are available are low. Simulation-based training effectively improves knowledge and simulated skills, but the effectiveness of training on clinical behaviour and patient outcome is not yet fully understood. The aim of this study was to assess the effect of obstetric simulation-based training on the incidence of PPH and clinical performance of basic delivery skills and management of PPH...
September 11, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28892596/peyronie-s-disease-watch-out-for-the-bend
#16
Christopher Love, Darren J Katz, Eric Chung, Ohad Shoshany
BACKGROUND: Peyronie's disease is a relatively common condition in urological practice, but is still poorly identified and understood in the wider medical community and by most of the public. Identifying the condition and appropriate referral for expert opinion can significantly lessen the physical and psychological effect on patients. OBJECTIVE: The objective of this article is to provide general practitioners with a concise and updated review of Peyronie's disease, with the aim of helping them to provide appropriate advice to their patients...
September 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28892054/long-lived-force-patterns-and-deformation-waves-at-repulsive-epithelial-boundaries
#17
Pilar Rodríguez-Franco, Agustí Brugués, Ariadna Marín-Llauradó, Vito Conte, Guiomar Solanas, Eduard Batlle, Jeffrey J Fredberg, Pere Roca-Cusachs, Raimon Sunyer, Xavier Trepat
For an organism to develop and maintain homeostasis, cell types with distinct functions must often be separated by physical boundaries. The formation and maintenance of such boundaries are commonly attributed to mechanisms restricted to the cells lining the boundary. Here we show that, besides these local subcellular mechanisms, the formation and maintenance of tissue boundaries involves long-lived, long-ranged mechanical events. Following contact between two epithelial monolayers expressing, respectively, EphB2 and its ligand ephrinB1, both monolayers exhibit oscillatory patterns of traction forces and intercellular stresses that tend to pull cell-matrix adhesions away from the boundary...
September 11, 2017: Nature Materials
https://www.readbyqxmd.com/read/28889406/intrapartum-transperineal-ultrasound-used-to-predict-cases-of-complicated-operative-vacuum-and-forceps-deliveries-in-nulliparous-women
#18
José Antonio Sainz, José Antonio García-Mejido, Adriana Aquise, María José Bonomi, Carlota Borrero, Paloma De la Fuente, Ana Fernández-Palacín
INTRODUCTION: The objective of this study was to investigate the predictive value of intrapartum transperineal ultrasound in the identification of complicated operative(vacuum or forceps) deliveries in nulliparous women. MATERIAL AND METHODS: Prospective observational study of nulliparous women with an indication for operative-delivery who underwent intrapartum transperineal ultrasound before fetal extraction. Managing obstetricians were blinded to the ultrasound data...
September 10, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28889030/crowdfunding-our-health-economic-risks-and-benefits
#19
Matthew J Renwick, Elias Mossialos
Crowdfunding is an expanding form of alternative financing that is gaining traction in the health sector. This article presents a typology for crowdfunded health projects and a review of the main economic benefits and risks of crowdfunding in the health market. We use evidence from a literature review, complimented by expert interviews, to extend the fundamental principles and established theories of crowdfunding to a health market context. Crowdfunded health projects can be classified into four types according to the venture's purpose and funding method...
August 31, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28884810/comparison-between-the-valsalva-maneuver-and-intraoperative-traction-measurements-in-pelvic-organ-prolapse-assessment
#20
Stergios K Doumouchtsis, Nivedita Gauthaman, Azar Khunda, Maya Basu, Kiran Dadhwal, Yasmin V Gayle, Constantin M Durnea
OBJECTIVE: To compare the assessment of pelvic organ prolapse (POP) between the Pelvic Organ Prolapse Quantification (POP-Q) system with Valsalva maneuver and intraoperative measurement with mechanical traction. METHODS: A prospective observational study included 100 women with POP attending a tertiary urogynecology clinic in the UK and undergoing vaginal prolapse surgical procedures between October 2011 and October 2014. The women were examined in the clinic using POP-Q with the Valsalva maneuver and in the operating theater under general anesthesia with mechanical traction...
September 8, 2017: International Journal of Gynaecology and Obstetrics
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