Praveen N K Pitchan Velammal, Suryakumar Balasubramanian, Fathima Shehnaz Ayoobkhan, Gautham V K Mohan, Pearl Aggarwal, Ali A Rabaan, Syed A Khan, Farah Yasmin, Thoyaja Koritala, Salim R Surani
INTRODUCTION: Down syndrome (DS) is associated with multiple comorbid conditions and chronic immune dysfunction. Persons with DS who contract COVID-19 are at high risk for complications and have a poor prognosis. We aimed to study the clinical symptoms, laboratory and biochemical profiles, radiologic findings, treatment, and outcomes of patients with DS and COVID-19. METHOD: We systematically searched PubMed, MEDLINE, Web of Science, Scopus, and the Cochrane Library using the keywords COVID-19 or coronavirus or SARS-CoV-2 and DS or trisomy 21...
March 2024: Immunity, Inflammation and Disease