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Early gastric cancer surgery

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https://www.readbyqxmd.com/read/29133255/high-prevalence-of-barrett-s-esophagus-and-esophageal-squamous-cell-carcinoma-after-repair-of-esophageal-atresia
#1
Floor W T Vergouwe, Hanneke IJsselstijn, Katharina Biermann, Nicole S Erler, René M H Wijnen, Marco J Bruno, Manon C W Spaander
BACKGROUND & AIMS: Esophageal atresia is rare, but improved surgical and intensive care techniques have increased rates of survival in children, so there are now many adults with this disorder. Many patients with esophageal atresia develop gastroesophageal reflux (GER), raising concerns about increased risk of Barrett's esophagus (BE; prevalence of 1.3%-1.6% in general population) and esophageal carcinoma. We assessed the prevalence of BE and esophageal carcinoma in this population. METHODS: We performed a prospective study of 289 patients with esophageal atresia at the Department of Gastroenterology and Hepatology at Erasmus MC University Medical Center in The Netherlands, from May 2012 through March 2017...
November 10, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29130228/-valuation-and-prospect-of-function-preserving-gastrectomy
#2
Shuchang Wang, Site Yu, Jia Xu, Gang Zhao
Preserving gastric function and improving quality of life (QOL) is the tendency of surgery for early gastric cancer. Function preserving gastrectomy (FPG) is applied to modify the extent of surgery and to achieve better quality of life at the premise of radical resection. Pylorus-preserving gastrectomy is the most favorable approach of FPG with oncological safety, which can improve nutritional status and QOL via preserving pylorus and vagal nerve. Proximal gastrectomy is widely accepted as FPG for early upper 1/3 gastric cancer...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29130221/-development-and-progress-of-diagnosis-and-treatment-for-gastric-cancer-in-china-what-inspiration-we-gained-from-japan-and-korea
#3
Enhao Zhao, Hui Cao
The incidence of gastric cancer in East Asia is highest in the world. Level of screening and inspection in high risk population, diagnosis and treatment in early stage, standardized surgery, minimally invasive techniques and clinical research always reach the international lead. In the past few years, the surgeons and researchers from China have already made considerable progress by learning the experience from Japan and Korea. The early detection of gastric cancer increases annually, the minimally invasive surgeries including endoscopic or laparoscopic operations are widely used, the standard surgical procedure and lymphadenectomy are popularized, meanwhile the clinical research for gastric cancer has also started...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29127549/preservation-of-the-celiac-branch-of-the-vagal-nerve-for-pylorus-preserving-gastrectomy-is-it-meaningful
#4
Haruna Furukawa, Manabu Ohashi, Michitaka Honda, Koshi Kumagai, Souya Nunobe, Takeshi Sano, Naoki Hiki
BACKGROUND: Preserving the hepatic and pyloric branches of the vagal nerve in laparoscopic pylorus-preserving gastrectomy (LPPG) is considered necessary to maintain the function of the pyloric cuff. However, the clinical benefits of preservation of the celiac branch of the vagal nerve (CBVN) remain unclear. METHODS: Of 391 patients who underwent LPPG for early gastric cancer, 116 patients in whom the CBVN was preserved (CBP group) and 58 patients in whom it was not preserved (non-CBP group) were selected through the propensity score-matching method...
November 10, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29081696/implication-of-gastric-cancer-molecular-genetic-markers-in-surgical-practice
#5
REVIEW
Marina V Nemtsova, Vladimir V Strelnikov, Alexander S Tanas, Igor I Bykov, Dmitry V Zaletaev, Viktoria V Rudenko, Alexander I Glukhov, Tatiana V Kchorobrich, Yi Li, Vadim V Tarasov, George E Barreto, Gjumrakch Aliev
INTRODUCTION: We have investigated aberrant methylation of genes CDH1, RASSF1A, MLH1, N33, DAPK, expression of genes hTERT, MMP7, MMP9, BIRC5 (survivin), PTGS2, and activity of telomerase of 106 gastric tumor samples obtained intra-operatively and 53 gastric tumor samples from the same group of patients obtained endoscopically before surgery. Biopsy specimens obtained from 50 patients with chronic calculous cholecystitis were used as a control group. Together with tissue samples obtained from different sites remote to tumors, a total of 727 samples have been studied...
October 2017: Current Genomics
https://www.readbyqxmd.com/read/29067581/serial-intermediate-term-quality-of-life-comparison-after-endoscopic-submucosal-dissection-versus-surgery-in-early-gastric-cancer-patients
#6
Young-Il Kim, Young Ae Kim, Chan Gyoo Kim, Keun Won Ryu, Young-Woo Kim, Jin Ah Sim, Young Ho Yun, Il Ju Choi
BACKGROUND: Endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) is expected to provide better long-term health-related quality of life (HRQOL) by preserving the entire stomach. We aimed to compare serial changes in HRQOL characteristics between patients who underwent ESD versus surgery for EGC. METHODS: A gastric cancer patient cohort was prospectively enrolled from 2004 to 2007. HRQOL of 161 EGC patients was prospectively assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC-QLQ-C30) and the stomach cancer-specific module EORTC-QLQ-STO22 at baseline (i...
October 24, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29066700/-a-case-of-laparoscopic-repair-of-internal-hernia-after-laparoscope-assisted-distal-gastrectomy-with-antecolic-roux-en-y-reconstruction
#7
Yukio Maezawa, Haruhiko Cho, Kazuki Kano, Tetsushi Nakajima, Kousuke Ikeda, Takanobu Yamada, Tsutomu Sato, Takashi Ohshima, Yasushi Rino, Munetaka Masuda, Takashi Ogata, Takaki Yoshikawa
A 72-year-old woman had undergone laparoscope-assisted distal gastrectomy with D1 plus lymph node dissection and antecolic Roux-en-Y reconstruction for early gastric cancer. She visited our department outpatient clinic with left upper abdominal pain 1 year and 9 months after the surgery. CT revealed a spiral sign of the superior mesenteric arteriovenous branch. An internal hernia was suspected on hospitalization. Although abdominal symptoms were relieved by conservative treatment, the hernia persisted. Laparoscopic surgery was performed and revealed that almost entire small intestine had been affected due to Petersen's defect...
October 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29058068/clinical-outcomes-of-gastric-cancer-patients-who-underwent-proximal-or-total-gastrectomy-a-propensity-score-matched-analysis
#8
Yuki Ushimaru, Yoshiyuki Fujiwara, Yuji Shishido, Yoshitomo Yanagimoto, Jeong-Ho Moon, Keijiro Sugimura, Takeshi Omori, Hiroshi Miyata, Masahiko Yano
BACKGROUND: Total gastrectomy (TG) and proximal gastrectomy (PG) are used to treat upper-third early gastric cancer. To date, no consensus has been reached regarding which procedure should be selected. The aim of this study was to validate the usefulness of preserving the stomach in early upper-third gastric cancer. METHODS: Between 2004 and 2013, 201 patients underwent PG or TG at our institution for treatment of upper-third early gastric cancer. According to the defined inclusion and exclusion criteria, 192 cases were enrolled in this study...
October 20, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29052085/comparison-of-young-patients-with-gastric-cancer-in-the-united-states-and-china
#9
Vivian E Strong, Ashley Russo, Sam S Yoon, Murray F Brennan, Daniel G Coit, Chao-Hui Zheng, Ping Li, Chang-Ming Huang
BACKGROUND: This study aimed to compare the clinicopathologic characteristics and stage-specific prognosis of young patients with gastric cancer (GC) after curative resection (R0) in the United States and China. METHODS: Data were collected on young patients (age ≤40 years) undergoing R0 resection at one U.S. (n = 79) and one Chinese (n = 257) institution. Patient, surgical, and pathologic variables and stage-specific survival rates were compared. Factors associated with 5-year disease-specific survival (DSS) were determined via multivariate analysis...
December 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29052072/long-term-outcomes-of-endoscopic-submucosal-dissection-in-comparison-to-surgery-in-undifferentiated-type-intramucosal-gastric-cancer-using-propensity-score-analysis
#10
Jun Chul Park, Yong Kang Lee, Soon Young Kim, Yunho Roh, Kyu Yeon Hahn, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Sung Hoon Noh
BACKGROUND: The treatment of intramucosal early gastric cancer with undifferentiated-type histologies (UD-EGCs) using endoscopic submucosal dissection (ESD) is controversial. This study aimed to compare the clinical and oncologic long-term outcomes of ESD and surgery for UD-EGCs. METHODS: A prospectively collected database of patients who underwent ESD or surgery between January 2006 and December 2012 was established. Patients who diagnosed with UD-EGC and satisfied the expanded indications of ESD were included...
October 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29052052/long-term-outcomes-of-endoscopic-submucosal-dissection-versus-surgery-in-early-gastric-cancer-meeting-expanded-indication-including-undifferentiated-type-tumors-a-criteria-based-analysis
#11
Sunpyo Lee, Kee Don Choi, Minkyu Han, Hee Kyong Na, Ji Yong Ahn, Kee Wook Jung, Jeong Hoon Lee, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Jeong-Hwan Yook, Byung Sik Kim, Hwoon-Yong Jung
BACKGROUND: Endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) meeting the expanded indication is considered investigational. We aimed to compare long-term outcomes of ESD and surgery for EGC in the expanded indication based on each criterion. METHODS: This study included 1823 consecutive EGC patients meeting expanded indication conditions and treated at a tertiary referral center: 916 and 907 patients underwent surgery or ESD, respectively. The expanded indication included four discrete criteria: (I) intramucosal differentiated tumor, without ulcers, size >2 cm; (II) intramucosal differentiated tumor, with ulcers, size ≤3 cm; (III) intramucosal undifferentiated tumor, without ulcers, size ≤2 cm; and (IV) submucosal invasion <500 μm (sm1), differentiated tumor, size ≤3 cm...
October 19, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/29051398/relationship-between-postoperative-complications-and-survival-after-gastrectomy-for-cancer
#12
Paolo Del Rio, Emiliano Bernuzzi, Elisa Bertocchi, Lorenzo Viani, Federico Cozzani, Chiara Montana
BACKGROUND: Surgical resection remains the main curative treatment for gastric cancer but is still affected by high postoperative morbidity and mortality rates, especially in Western countries. MATERIALS AND METHODS: We've analyzed patients treated for gastric cancer at our Operative Unit of ent, extent of lymphadenectomy and survival. General Surgery and Organ Transplantation of the University Hospital of Parma from January 2006 till December 2010, relating the occurrence of eventual complications to sex, age at diagnosis, definitive histological examination, type and duration of surgical treatment...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29046960/endoscopic-submucosal-dissection-for-undifferentiated-type-early-gastric-cancer-short-and-long-term-outcomes
#13
Hye Kyung Jeon, Seong Jun Lee, Gwang Ha Kim, Do Youn Park, Bong Eun Lee, Geun Am Song
BACKGROUND AND AIMS: Application of endoscopic submucosal dissection (ESD) for undifferentiated-type early gastric cancers (EGCs) remains controversial owing to limited data regarding long-term outcomes. We aimed to evaluate the feasibility of ESD for undifferentiated-type EGCs that meet the expanded criteria (EC). METHODS: We performed a retrospective analysis of 66 patients who underwent ESD for undifferentiated-type EGC between January 2005 and December 2014...
October 18, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29034350/function-preserving-surgery-for-gastric-cancer-current-status-and-future-perspectives
#14
REVIEW
Souya Nunobe, Naoki Hiki
The number of early gastric cancer (EGC) cases has been increasing because of improved diagnostic procedures including endoscopy and screening systems. Therefore, function-preserving gastrectomy (FPG) for EGC with the expectation of better quality of life (QOL) after surgery may be increasingly utilized, due to its association with low rate of lymph node metastasis and excellent survival and the possibility of employing less invasive procedures such as laparoscopic gastrectomy in combination. Pylorus-preserving gastrectomy (PPG) with curative intent lymph node dissection is a representative FPG that has been used in EGC, and its superiorities, indications, limitations, and survival benefits have already been reported in several retrospective studies...
2017: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29031882/long-term-outcomes-after-noncurative-endoscopic-resection-of-early-gastric-cancer-the-optimal-time-for-additional-endoscopic-treatment
#15
Mi Young Jeon, Jun Chul Park, Kyu Yeon Hahn, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee
BACKGROUND AND AIMS: We aimed to evaluate long-term outcomes with noncurative endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) and surveillance strategies such as the optimal time for additional endoscopic treatment in patients with noncurative ESD. METHODS: Of 2,527 patients who underwent gastric ESD for EGC, 512 (20.3%) patients with noncurative resection were reviewed. Noncurative resection is defined as histological positivity of the resected margins, lymphovascular infiltration (LVI), or beyond the expanded criteria for ESD...
October 12, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29023334/application-of-enhanced-recovery-after-surgery-in-single-incision-laparoscopic-distal-gastrectomy
#16
Junfeng Zhou, Qingliang He, Jiaxing Wang, Qicai Liu, Mi Wang
BACKGROUND: Recently, enhanced recovery after surgery (ERAS) was widely used in the perioperative management of gastric cancer. The study aimed to evaluate the safety and effectiveness of ERAS in single-incision laparoscopic distal gastrectomy (SIDG). MATERIALS AND METHODS: A total of 90 patients who received laparoscopic gastric cancer resection were divided into 3 groups: group A (n=30), underwent traditional multiport laparoscopic distal gastrectomy with conventional perioperative management; group B (n=30) underwent traditional multiport laparoscopic distal gastrectomy with ERAS concept; and group C (n=30), underwent SIDG with ERAS concept...
October 11, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29019560/pancreatoduodenectomy-brazilian-practice-patterns
#17
Orlando Jorge M Torres, Eduardo de Souza M Fernandes, Rodrigo Rodrigues Vasques, Fabio Luís Waechter, Paulo Cezar G Amaral, Marcelo Bruno de Rezende, Roland Montenegro Costa, André Luís Montagnini
BACKGROUND: Pancreatoduodenectomy is a technically challenging surgical procedure with an incidence of postoperative complications ranging from 30% to 61%. The procedure requires a high level of experience, and to minimize surgery-related complications and mortality, a high-quality standard surgery is imperative. AIM: To understand the Brazilian practice patterns for pancreatoduodenectomy. METHOD: A questionnaire was designed to obtain an overview of the surgical practice in pancreatic cancer, specific training, and experience in pancreatoduodenectomy...
July 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28987558/endoscopic-resection-versus-radical-gastrectomy-for-early-gastric-cancer-in-asia-a-meta-analysis
#18
REVIEW
Fei-Long Ning, Chun-Dong Zhang, Peng Wang, Shuai Shao, Dong-Qiu Dai
BACKGROUND: To compare the efficacy and safety of endoscopic resection (ER) and radical gastrectomy (RG) for early gastric cancer (EGC) in Asia. MATERIALS AND METHODS: We systematically searched relevant articles published before September 1, 2017. We evaluated the quality of the included non-randomized studies using the Newcastle-Ottawa Scale (NOS). Meta-analysis was carried out using RevMan 5.3 software. The odds ratio (OR) with 95% confidence intervals (CI) were used for the dichotomous data...
October 5, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28983696/is-the-ecura-system-useful-for-selecting-patients-who-require-radical-surgery-after-noncurative-endoscopic-submucosal-dissection-for-early-gastric-cancer-a-comparative-study
#19
Waku Hatta, Takuji Gotoda, Tsuneo Oyama, Noboru Kawata, Akiko Takahashi, Yoshikazu Yoshifuku, Shu Hoteya, Masahiro Nakagawa, Masaaki Hirano, Mitsuru Esaki, Mitsuru Matsuda, Ken Ohnita, Kohei Yamanouchi, Motoyuki Yoshida, Osamu Dohi, Jun Takada, Keiko Tanaka, Shinya Yamada, Tsuyotoshi Tsuji, Hirotaka Ito, Yoshiaki Hayashi, Tomohiro Nakamura, Naoki Nakaya, Tooru Shimosegawa
BACKGROUND: We have established a risk-scoring system, termed the "eCura system," for the risk stratification of lymph node metastasis in patients who have received noncurative endoscopic submucosal dissection (ESD) for early gastric cancer (EGC). We aimed to clarify whether this system contributes to the selection of patients requiring radical surgery after ESD. METHODS: Between 2000 and 2011, 1,969 patients with noncurative ESD for EGC were included in this multicenter study...
October 5, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28983577/early-experience-with-robot-assisted-laparoscopic-hepatobiliary-and-pancreatic-surgery-in-singapore-single-institution-experience-with-20-consecutive-patients
#20
Brian Kp Goh, Ser-Yee Lee, Chung-Yip Chan, Jen-San Wong, Peng-Chung Cheow, Alexander Yf Chung, London Lpj Ooi
INTRODUCTION: Presently, experience with robot-assisted laparoscopic (RAL) hepatobiliary and pancreatic (HPB) surgery remains limited worldwide. In this study, we report our early experience with RAL HPB surgery in Singapore. METHODS: A retrospective review was conducted of the first 20 consecutive patients who underwent RAL HPB surgery at a single institution over a 34-month period from February 2013 to November 2015. The 20 cases were performed by three principal surgeons, of which 17 (85...
October 6, 2017: Singapore Medical Journal
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