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Early gastric cancer surgery

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https://www.readbyqxmd.com/read/28110398/simultaneous-robotic-subtotal-gastrectomy-and-right-hemicolectomy-for-synchronous-adenocarcinoma-of-stomach-and-colon
#1
Byoung Jo Suh, Sung Jin Oh, Jin Yong Shin, Do Hoon Ku, Dong Sik Bae, Jong Kwon Park
Simultaneous laparoscopy-assisted resection for synchronous stomach and colon cancers has been reported frequently; however, robot-assisted gastrectomy and colectomy for these conditions are rarely reported. We report the successful use of robotic surgery for synchronous cancers of the stomach and colon. A 71-year-old woman with no specific medical history was diagnosed with early gastric cancer at the gastric angle and right colon cancer after undergoing esophagogastroduodenoscopy and colonofiberoscopy. Abdomino-pelvic computed tomography revealed that the stomach and colon lesions were limited to the mucosa without any lymph nodes or distant metastasis, which suggested the clinical stage for both cancers as T1N0M0...
January 21, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28101302/robot-assisted-laparoscopic-gastrectomy-for-gastric-cancer
#2
REVIEW
Stefano Caruso, Franco Franceschini, Alberto Patriti, Franco Roviello, Mario Annecchiarico, Graziano Ceccarelli, Andrea Coratti
Phase III evidence in the shape of a series of randomized controlled trials and meta-analyses has shown that laparoscopic gastrectomy is safe and gives better short-term results with respect to the traditional open technique for early-stage gastric cancer. In fact, in the East laparoscopic gastrectomy has become routine for early-stage gastric cancer. In contrast, the treatment of advanced gastric cancer through a minimally invasive way is still a debated issue, mostly due to worries about its oncological efficacy and the difficulty of carrying out an extended lymphadenectomy and intestinal reconstruction after total gastrectomy laparoscopically...
January 16, 2017: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28100248/mediastinal-lymph-node-dissection-and-distal-esophagectomy-is-not-essential-in-early-esophagogastric-junction-adenocarcinoma
#3
In-Seob Lee, Ji-Yong Ahn, Jeong-Hwan Yook, Byung-Sik Kim
BACKGROUND: Optimal extent of surgery remains controversial in types 2 and 3 adenocarcinoma of esophagogastric junction (AEG). We aimed to determine whether the extended procedure including mediastinal lymphadenectomy is essential in all patients with AEG by comparing prognosis and recurrence of proximal gastric adenocarcinoma based on total gastrectomy with intra-abdominal lymphadenectomy. METHODS: The clinicopathologic characteristics of 672 patients (type 2: 90, type 3: 211, upper third of the stomach: 371 cases) who underwent curative total gastrectomy with lymphadenectomy between 2003 and 2009 were reviewed...
January 18, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28050659/ischemic-gastric-conditioning-by-preoperative-arterial-embolization-before-oncologic-esophagectomy-a-single-center-experience
#4
Julien Ghelfi, Pierre-Yves Brichon, Julien Frandon, Bastien Boussat, Ivan Bricault, Gilbert Ferretti, Sébastien Guigard, Christian Sengel
PURPOSE: Surgical esophagectomy is the gold standard treatment of early-stage esophageal cancer. The procedure is complicated with significant morbidity; the most severe complication being the anastomotic leakage. Anastomotic fistulas are reported in 5-25% of cases and are mainly due to gastric transplant ischemia. Here, we report our experience of ischemic pre-conditioning using preoperative arterial embolization (PreopAE) before esophagectomy. MATERIALS AND METHODS: The medical records of all patients who underwent oncologic esophagectomy from 2008 to 2015 were retrospectively reviewed...
January 3, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28004249/delayed-perforation-occurring-on-the-24th-day-after-endoscopic-submucosal-dissection-for-early-gastric-cancer
#5
Satoru Homma, Kazuaki Tokodai, Minami Watanabe, Kai Takaya, Eiji Hashizume
Delayed perforation occurs after 0.5% of endoscopic submucosal dissection (ESD) procedures for early gastric cancer (EGC). This complication can occur within a few hours or days after ESD. There are few reports in the English literature concerning patients who developed delayed perforation after ESD for EGC. An 81-year-old woman was referred to the emergency department of our hospital on the 24th day after ESD because of abdominal pain. We diagnosed her with delayed perforation with peritonitis after ESD for EGC using computed tomography (CT) and esophagogastroduodenoscopy (EGD)...
December 21, 2016: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28002507/narrow-band-imaging-endoscopy-for-detection-of-precancerous-lesions-of-upper-gastrointestinal-tract
#6
Dan Nicolae Florescu, Elena Tatiana Ivan, Adriana Mihaela Ciocâlteu, Ioana Andreea Gheonea, Diana Rodica Tudoraşcu, Tudorel Ciurea, Dan IonuŢ Gheonea
Gastric cancer (GC) is an important health problem despite the advances in surgery and chemotherapy and although the incidence is decreasing, GC is still considered the second most common cause of deceases produced by cancer. Survival rates in gastric cancer are low, mainly because most patients are often diagnosed in late stages. The current interest in the diagnostic of GC is the detection of early gastric cancer. Advances in high-resolution endoscopic techniques such as narrow band imaging (NBI) allow the detection of early precancerous lesions like polyps or metaplastic mucosa...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27999935/laparoscopic-sentinel-node-navigation-surgery-for-early-gastric-cancer-a-prospective-multicenter-trial
#7
Naoto Takahashi, Hiroshi Nimura, Tetsuji Fujita, Norio Mitsumori, Norio Shiraishi, Seigo Kitano, Hitoshi Satodate, Katsuhiko Yanaga
BACKGROUND: Prospective multicenter trials have shown the feasibility of sentinel node (SN) navigation surgery using a dual tracer of dye and radioisotope for early gastric cancer. However, comparable trials using the indocyanine green (ICG) and the infrared ray laparoscopic system (IRLS) have not been reported. On the basis of our cohort studies, we assumed that the ICG imaging with the IRLS is as effective as the dual tracer in detecting SNs. Therefore, we conducted a prospective multicenter trial to assess the effectiveness and generalizability of the infrared ICG technique in patients with early gastric cancer...
December 20, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27995482/comparison-of-long-term-outcomes-of-endoscopic-submucosal-dissection-and-surgery-for-esophagogastric-junction-adenocarcinoma
#8
Eun Jeong Gong, Do Hoon Kim, Ji Yong Ahn, Kee Wook Jung, Jeong Hoon Lee, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung, Hee Sung Kim, In-Seob Lee, Beom Su Kim, Moon-Won Yoo, Sung Tae Oh, Jeong Hwan Yook, Byung Sik Kim
BACKGROUND: Endoscopic submucosal dissection (ESD) has become accepted as the standard treatment for early gastric cancer. However, comparative outcomes of ESD and surgery have not been evaluated for adenocarcinoma in the esophagogastric junction (EGJ). We investigated the long-term outcomes of ESD compared with those of surgery for adenocarcinoma in the EGJ. METHODS: Patients who underwent ESD or surgery for Siewert type II adenocarcinoma between 2005 and 2010 and who met the absolute and expanded criteria for endoscopic resection were eligible...
December 19, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/27995193/chromoendoscopy-in-combination-with-random-biopsies-does-not-improve-detection-of-gastric-cancer-foci-in-cdh1-mutation-positive-patients
#9
Robert Hüneburg, Tim Marwitz, Peer van Heteren, Tobias J Weismüller, Jonel Trebicka, Ronja Adam, Stefan Aretz, Alberto Perez Bouza, Dimitrios Pantelis, Jörg C Kalff, Jacob Nattermann, Cristian P Strassburg
Background and study aims: Hereditary diffuse gastric cancer (HGGC), an autosomal dominant tumor-syndrome, accounts for 1 % to 3 % of gastric cancers worldwide. Presumably 30 % to 40 % of all patients fulfilling the clinical guidelines for HDGC are carriers of a pathogenic mutation in the CDH1 gene. Patients often show multiple foci of signet ring cell carcinoma at early age and are advised to undergo prophylactic total gastrectomy (PTG). Our aim was to improve the endoscopic detection of HDGC by using an enhanced endoscopic protocol...
December 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27995033/extremely-high-expression-of-serum-alpha-fetoprotein-level-of-gastric-adenocarcinoma-a-rare-case-with-an-unexpected-well-prognosis
#10
Weihua Gong, Dawei Shou, Ping Gong
INTRODUCTION: Alpha-fetoprotein (AFP)-producing gastric cancer is a relatively rare form of stomach malignancy. Patients with higher serum AFP level (>300 ng/mL) will have a poorer prognosis. CASE DESCRIPTION: In this study, we present a case of 77-year-old woman with an extremely high expression of serum AFP level (>10,000 ng/mL) of gastric cancer. Histological examination revealed gastric adenocarcinoma (Bormann III gastric tumor) invading into the serosal layer and vessel...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27979733/preoperative-metabolic-syndrome-is-predictive-of-significant-gastric-cancer-mortality-after-gastrectomy-the-fujian-prospective-investigation-of-cancer-fiesta-study
#11
Dan Hu, Feng Peng, Xiandong Lin, Gang Chen, Hejun Zhang, Binying Liang, Kaida Ji, Jinxiu Lin, Lin-Feng Chen, Xiongwei Zheng, Wenquan Niu
Metabolic syndrome (MetS) has been shown to be associated with an increased risk of gastric cancer. However, the impact of MetS on gastric cancer mortality remains largely unknown. Here, we prospectively examined the prediction of preoperative MetS for gastric cancer mortality by analyzing a subset of data from the ongoing Fujian prospective investigation of cancer (FIESTA) study. This study was conducted among 3012 patients with gastric cancer who received radical gastrectomy between 2000 and 2010. The latest follow-up was completed in 2015...
February 2017: EBioMedicine
https://www.readbyqxmd.com/read/27933396/totally-laparoscopic-total-gastrectomy-using-the-overlap-method-early-outcomes-of-50-consecutive-cases
#12
Tae-Gyun Lee, In-Seob Lee, Jeong-Hwan Yook, Byung-Sik Kim
BACKGROUND: Construction of an esophagojejunostomy is still a challenging procedure in totally laparoscopic total gastrectomy (TLTG), and there is no standard anastomosing method. The aims of this study were to describe our TLTG with the overlap method using a linear stapler and report surgical outcomes. METHODS: From January 2015 to April 2016, 50 patients underwent TLTG using the overlap method for gastric cancer. The procedures were performed by a single surgeon, and the patients' medical records were reviewed...
December 8, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27928446/gastrostomy-with-peritoneal-collar-versus-percutaneous-endoscopic-gastrostomy
#13
Tudor C, Branescu C, Savlovschi C, El-Khatib A, Pantu H, Nica A, Dascalu Am, Masoumeh B, Tudor As, Oprescu Sm, Serban D
Aim. The present study aimed to perform a medico-surgical comparative analysis of the 2 most widely used techniques: gastrostomy with peritoneal collar versus percutaneous endoscopic gastrostomy, based on the vast clinical experience in an Upper Digestive Surgery Clinic. Materials and method. A retrospective study was carried out between January 2010 and January 2015 on the patients admitted for a surgical solution for feeding. The indications, preoperative preparation, surgical techniques, and postoperative outcomes were analyzed...
October 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27921193/an-isoperistaltic-jejunum-later-cut-overlap-method-for-esophagojejunostomy-anastomosis-after-totally-laparoscopic-total-gastrectomy-a-safe-and-feasible-technique
#14
Chang-Ming Huang, Ze-Ning Huang, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu
BACKGROUND: Intracorporeal anastomosis after totally laparoscopic total gastrectomy (TLTG) has been increasingly applied. (1-7) We assessed the intracorporeal isoperistaltic jejunum-later-cut overlap method (IJOM) for esophagojejunostomy anastomosis (EA). METHODS: From January to June 2014, a total of 19 patients with resectable gastric cancer (cT1-T4aNOM0) underwent TLTG. IJOM was performed by creating side-to-side stapled anastomosis through enterotomies proximal to the left esophageal resection margin and on the antimesenteric jejunal border, 30 cm distal to the Trietz ligament...
December 5, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27919972/clinical-burden-of-c-reactive-protein-albumin-ratio-before-curative-surgery-for-patients-with-gastric-cancer
#15
Yuji Toiyama, Tadanobu Shimura, Hiromi Yasuda, Hiroyuki Fujikawa, Yoshiki Okita, Minako Kobayashi, Masaki Ohi, Shigeyuki Yoshiyama, Jyunichiro Hiro, Toshimitsu Araki, Yasuhiro Inoue, Yasuhiko Mohri, Masato Kusunoki
To assess the relationship of C-reactive protein/albumin ratio (CAR) to outcomes and surgical site infection (SSI) in gastric cancer (GC) treated with curative intent, we retrospectively assessed 384 patients with GC for CAR, SSIs, disease-free survival (DFS), overall survival (OS) and other factors. We found SSIs in 42 patients (10.9%). Pathological T-stage, TNM classification, body mass index, duration of surgery, blood loss and preoperative CAR were significantly associated with SSIs; in multivariate analyses, CAR [hazard ratio (HR)=2...
2016: Anticancer Research
https://www.readbyqxmd.com/read/27877009/characteristics-of-gastric-cancer-recurrence-five-or-more-years-after-curative-gastrectomy
#16
Chang-Hyun Shin, Woo-Yong Lee, Seung-Woo Hong, Yeo-Goo Chang
OBJECTIVE: To investigate the characteristics of recurrences that occurred 5 or more years after curative resection for gastric cancer. METHODS: We analyzed recurrences among 1,299 patients with gastric cancer who underwent curative operations at the Department of Surgery, Inje University Seoul Paik Hospital between September 1998 and December 2002. Recurrences were classified as within 2 years (early), 2-5 years (intermediate), and more than 5 years (late) after gastrectomy...
October 2016: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/27875094/laparoscopic-radical-gastrectomy-for-resectable-advanced-gastric-cancer-within-enhanced-recovery-programs-a-prospective-randomized-controlled-trial
#17
Xia Mingjie, Zhang Luyao, Tang Ze, Zhao YinQuan, Wang Quan
BACKGROUND: Enhanced recovery programs have become an important focus of perioperative management. A few studies have demonstrated the efficacy of an enhanced recovery after surgery (ERAS, which includes optimized pain control, restricted I.V. fluids, early initiation of postoperative oral feeding, and enforced mobilization) protocol in patients undergoing radical gastrectomy. We investigated the feasibility and safety of laparoscopic radical gastrectomy within ERAS programs. METHODS: In this single-center prospective randomized controlled trial conducted between September 2013 and August 2014, 149 consecutive locally advanced gastric cancer patients (T2-4, any N, M0) diagnosed by the CT scanning were allocated to either ERAS group (N = 73) or conventional pathway group (N = 76)...
November 22, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27837291/the-psychosocial-impact-of-undergoing-prophylactic-total-gastrectomy-ptg-to-manage-the-risk-of-hereditary-diffuse-gastric-cancer-hdgc
#18
Nina Hallowell, Julia Lawton, Shirlene Badger, Sue Richardson, Richard H Hardwick, Carlos Caldas, Rebecca C Fitzgerald
Individuals identified as at high risk of developing Hereditary Diffuse Gastric Cancer (HDGC) are advised to undergo prophylactic surgery - have their stomach removed - in their early twenties. Research with (older) cancer patients who undergo gastrectomy for curative reasons suggests that gastric resection has a number of physical and psychosocial sequelae. Because it is difficult to extrapolate the findings of studies of older cancer patients to younger healthy patients who are considering prophylactic total gastrectomy (PTG), the aim of this qualitative interview study was to determine the psychosocial implications of undergoing prophylactic surgery to manage genetic risk...
November 11, 2016: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/27814271/the-role-of-red-cell-distribution-width-in-the-prognosis-of-patients-with-gastric-cancer
#19
Pinar Yazici, Uygar Demir, Emre Bozkurt, Gurhan R Isil, Mehmet Mihmanli
BACKGROUND: Although the red cell distribution width (RDW) has been reported as a reliable predictor of prognosis in several types of cancer, to our knowledge the prognostic value of RDW in gastric carcinoma has not been studied, so far. OBJECTIVE: We aimed to investigate the role of red cell distribution width (RDW) in predicting prognosis in gastric cancer patients. METHODS: All gastric cancer patients who underwent curative surgery (n= 172, 110M/62F) over a five-year study period were evaluated...
October 28, 2016: Cancer Biomarkers: Section A of Disease Markers
https://www.readbyqxmd.com/read/27778124/early-detection-of-nonperitoneal-recurrence-may-contribute-to-survival-benefit-after-curative-gastrectomy-for-gastric-cancer
#20
Keiichi Fujiya, Masanori Tokunaga, Rie Makuuchi, Noriyuki Nishiwaki, Hayato Omori, Wataru Takagi, Fumiko Hirata, Makoto Hikage, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Masanori Terashima
BACKGROUND: There is no evidence that strict follow-up using cross-sectional imaging after curative gastrectomy benefits survival; however, nonperitoneal recurrence detected early might be treated with additional surgery. The present study examined whether early detection of recurrence by imaging modalities could increase survival, particularly in patients with nonperitoneal recurrence. METHODS: We retrospectively analyzed 218 patients with recurrent gastric cancer after curative gastrectomy performed from 2002 to 2014...
October 24, 2016: Gastric Cancer
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