keyword
MENU ▼
Read by QxMD icon Read
search

Stomach GIST

keyword
https://www.readbyqxmd.com/read/29443783/giant-gist-of-the-stomach-a-successful-case-of-safe-resection-with-preoperative-simulation-using-three-dimensional-ct-angiography-case-report
#1
Kentaro Matsuo, Masaya Inoue, Yasutsugu Shirai, Tatsuki Kataoka, Shuji Kagota, Kohei Taniguchi, Sang-Woong Lee, Kazuhisa Uchiyama
RATIONALE: We report a very rare case of safely resectable giant gastrointestinal stromal tumor (GIST) with preoperative three-dimensional computed tomography (3D-CT) angiography in spite of no neoadjuvant treatment. PATIENT'S CONCERN: A 71-year-old woman presented to our hospital with an abdominal giant tumor. As this giant tumor could not be accurately diagnosed by preoperative investigation, we had to perform her surgical treatment without neoadjuvant treatment...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29441371/gastrointestinal-stromal-tumor-of-the-esophagus-current-issues-of-diagnosis-surgery-and-drug-therapy
#2
REVIEW
Jun Hihara, Hidenori Mukaida, Naoki Hirabayashi
Gastrointestinal stromal tumors (GISTs) often arise in the stomach and small intestine, while esophageal GISTs are rare. Due to their rarity, clinicopathological data on esophageal GISTs are extremely limited, and this results in a lack of clear recommendations concerning optimal surgical management for esophageal GISTs. It is difficult to distinguish esophageal GIST from leiomyoma, the most frequent esophageal mesenchymal tumor, prior to resection, because the two types of tumors appear similar on computed tomography (CT), endoscopic ultrasound (EUS), and 18F-fluorodeoxyglucose positron emission tomography (FDG-PET)...
2018: Translational Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29434135/multiple-synchronous-sporadic-gastrointestinal-stromal-tumors-in-the-stomach-and-jejunum
#3
Mami Tokunaga, Sohachi Nanjo, Hiroki Yoshita, Haruka Fujinami, Tohru Watanabe, Yoko Ishii, Saito Kobayashi, Momoko Akashi, Hiroaki Takagi, Hiroshi Mihara, Shinya Kajiura, Takayuki Ando, Isaya Hashimoto, Shozo Hojo, Tomoyuki Okumura, Toshiro Sugiyama
A 77-year-old patient was admitted to our hospital for the further examination of melena. A computed tomography scan detected two submucosal tumors (SMTs) in the stomach and jejunum. Double-balloon endoscopy revealed the presence of a delle on the jejunal SMT, suggesting that the SMT was the origin of the gastrointestinal bleeding. Both tumors were surgically resected and subsequently diagnosed via histology as gastrointestinal stromal tumors (GISTs). Furthermore, the two GISTs had different mutations in the c-kit gene, suggesting that they were derived from different clonal origins...
February 9, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29410603/the-expression-of-mdm2-in-gastrointestinal-stromal-tumors-immunohistochemical-analysis-of-35-cases
#4
Boubacar Efared, Gabrielle Atsame-Ebang, Layla Tahiri, Ibrahim Sory Sidibé, Fatimazahra Erregad, Nawal Hammas, Samia Arifi, Ihsane Mellouki, Abdelmalek Ousadden, Khalid Mazaz, Hinde El Fatemi, Laila Chbani
Background: Gastrointestinal stromal tumors (GIST) are the most common primary mesenchymal tumors of the digestive system. The assessment of their biological behavior still remains a scientific challenge. To date, there are no well-established biological prognostic markers of GIST. Our aim is to study the expression of the MDM2 oncoprotein in GIST through an immunohistochemical analysis. Methods: It was a retrospective study of 35 cases of GIST diagnosed from 2009 to 2012 in the department of pathology of Hassan II university hospital, Fès, Morocco...
2018: BMC Clinical Pathology
https://www.readbyqxmd.com/read/29394813/-a-long-term-survivor-who-are-responding-to-sunitinib-treatment-for-recurrent-imatinib-resistant-gastrointestinal-stromal-tumor-gist-of-the-stomach
#5
Kazuki Kano, Haruhiko Cho, Yukio Maezawa, Toru Aoyama, Tsutomu Hayashi, Takanobu Yamada, Tsutomu Sato, Takashi Oshima, Norio Yukawa, Yasushi Rino, Munetaka Masuda, Takashi Ogata, Takaki Yoshikawa
A 63-year-old man underwent a laparoscopic partial gastrectomy for GIST on September, 2001. Three years and 2 months after the gastrectomy, an abdominal CT showed multiple recurrences in S5 and S6 in the liver and peritoneum. After 4 months from the start of imatinib treatment(400mg/day), peritoneal tumors disappeared and the patient maintained stable disease by imatinib treatment for 8 years. However, on December, 2012, an abdominal CT scan revealed the regrowth of the tumor in S6 in the liver, and PET-CT showed focal progression of only the S6 lesion...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394755/-radical-resection-of-huge-gastrointestinal-stromal-tumor-of-the-stomach-following-neoadjuvant-chemotherapy-with-lmatinib-acase-report
#6
Yoko Hiraki, Hiroaki Kato, Osamu Shiraishi, Yumiko Tanaka, Mitsuru Iwama, Atsushi Yasuda, Masayuki Shinkai, Yutaka Kimura, Motohiro Imano, Haruhiko Imamoto, Takushi Yasuda
The usefulness and safety of imatinibfor neoadjuvant chemotherapy for resectable gastrointestinal stromal tumor(GIST) has not been established. We reported a case of a huge GIST of the stomach that was safely resected following preoperative imatinibtherapy. A 69-year-old man was hospitalized with abdominal fullness which increased rapidly from a month ago. A CT scan showed a huge tumor containing solid and cystic component which was accompanied by an extra-wall nodule. The tumor was strongly suspected to be originated from the stomach and EUS-FNA revealed GIST...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394616/-laparoscopic-local-resection-for-a-gastric-gist-with-ulcer-locating-near-to-the-esophagogastric-junction-a-case-report
#7
Yoshihiro Tanaka, Toshiyuki Kosuga, Shuhei Komatsu, Kazuma Okamoto, Katsutoshi Shoda, Tomohiro Arita, Hirotaka Konishi, Ryo Morimura, Yasutoshi Murayama, Atsushi Shiozaki, Yoshiaki Kuriu, Hisashi Ikoma, Masayoshi Nakanishi, Hitoshi Fujiwara, Eigo Otsuji
A 39-year-old woman visited our hospital because of epigastric pain. Gastrointestinal endoscopy revealed a gastric submucosal tumor, 30mm in size, with ulcer locating near to the esophagogastric junction, and it was diagnosed with GIST by the endoscopic ultrasonography-guided fine needle aspiration. Then, she underwent laparoscopic surgery for the removal of gastric GIST. After peeling around the upper stomach, the local resection of the stomach was performed with linear staplers in the minor axis direction under the vision of the endoscope and laparoscope...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29382014/calcifying-fibrous-tumor-of-stomach-a-case-report
#8
Bo-Jing Li, Xiao-Dan Yang, Wei-Xiang Chen, Yi-Hai Shi, Zhi-Hong Nie, Jian Wu
RATIONALE: Calcifying fibrous tumor (CFT) is a rare benign soft tissue mesenchymal neoplasm. Although the gastrointestinal (GI) tract is the most common predilection site of CFT, the clinicians, even including pathologist, generally consider it as GI stromal tumor (GIST) or other submucosal tumors such as schwannoma and leiomyoma. PATIENT CONCERNS: A 55-year-old man presented with complaints of epigastric discomfort and abdominal distention for more than 1 year...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29341147/genotype-and-risk-of-tumour-rupture-in-gastrointestinal-stromal-tumour
#9
K Boye, J-M Berner, I Hompland, Ø S Bruland, S Stoldt, K Sundby Hall, B Bjerkehagen, T Hølmebakk
BACKGROUND: Tumour rupture is a strong predictor of poor outcome in gastrointestinal stromal tumours (GISTs) of the stomach and small intestine. The objective was to determine whether tumour genotype was associated with risk of rupture. METHODS: Rupture was classified according to the definition proposed by the Oslo Sarcoma Group. Since January 2000, data were registered retrospectively for all patients at Oslo University Hospital undergoing surgery for localized GIST of the stomach or small intestine...
January 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29334307/regorafenib-regresses-an-imatinib-resistant-recurrent-gastrointestinal-stromal-tumor-gist-with-a-mutation-in-exons-11-and-17-in-a-patient-derived-orthotopic-xenograft-pdox-nude-mouse-model
#10
Kentaro Miyake, Kei Kawaguchi, Tasuku Kiyuna, Masuyo Miyake, Kentaro Igarashi, Zhiying Zhang, Takashi Murakami, Yunfeng Li, Scott D Nelson, Irmina Elliott, Tara Russell, Arun Singh, Yukihiko Hiroshima, Masashi Momiyama, Ryusei Matsuyama, Takashi Chisima, Itaru Endo, Fritz C Eilber, Robert M Hoffman
Gastrointestinal stromal tumor (GIST) is a rare type of sarcoma. The aim of this study was to determine drug sensitivity for a regionally-recurrent case of GIST using a patient-derived orthotopic xenograft (PDOX) model. The PDOX model was established in the anterior wall of the stomach. GIST PDOX models were randomized into 5 groups of 6 mice each when the tumor volume reached 60 mm3: G1, control group; G2, imatinib group (oral administration (p.o.), daily, for 3 weeks); G3, sunitinib group (p.o., daily, for 3 weeks); G4, regorafenib (p...
January 15, 2018: Cell Cycle
https://www.readbyqxmd.com/read/29275234/a-case-of-gastric-glomus-tumor-resection-using-laparoscopy-endoscopy-cooperative-surgery-lecs
#11
Taro Aoba, Takehito Kato, Kazuhiro Hiramatsu, Yoshihisa Shibata, Motoi Yoshihara, Naoya Yamaguchi, Tadahiro Kamiya
INTRODUCTION: Gastric glomus tumors are rare submucosal mesenchymal tumors. Because gastric glomus tumors are submucosal tumors and resemble gastrointestinal stromal tumors (GISTs), preoperative diagnosis is difficult. We present a case of gastric glomus tumor that was removed by laparoscopy endoscopy cooperative surgery (LECS). CASE PRESENTATION: A 67-year-old female was taken to the emergency room at our hospital due to epigastric pain. An upper gastrointestinal endoscopy revealed a submucosal tumor (SMT) located in the lesser curvature of the upper body of the stomach...
December 16, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29245294/gastrointestinal-stromal-tumor-of-unusual-phenotype-after-imatinib-treatment-a-case-report-and-diagnostic-utility-of-etv1-mrna-in-situ-hybridization
#12
Minsun Jung, Sung-Hye Park, Yoon Kyung Jeon, Jae-Kyung Won, Han-Kwang Yang, Woo Ho Kim
RATIONALE: Gastrointestinal stromal tumor (GIST) is the most common tumor of mesenchymal origin in gastrointestinal tract. Immunohistochemical (IHC) staining combined with a typical morphology is used for the diagnosis of GIST. Typically, IHC staining for v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene (KIT) and discovered on GIST-1(DOG1) is positive in almost all GISTs. However, imatinib mesylate, a specific inhibitor of KIT tyrosine kinase, frequently involves changes in the morphology and IHC staining of GIST, impeding the diagnosis...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29239342/transgastric-submucosal-excision-of-small-to-medium-sized-gastrointestinal-stromal-tumours-by-pure-minimally-invasive-approach
#13
Manash Ranjan Sahoo, Sumeet Deshpande, Shameel Ahmmed
AIM: The aim of this study is to evaluate the results of a single and common approach for transgastric submucosal excision of small- to medium-sized gastrointestinal stromal tumours (GIST) having different locations in upper two-third of the stomach by pure minimally invasive approach. MATERIALS AND METHODS: A retrospective study from February 2012 to January 2015 on 11 patients was conducted including both male and female. Their age ranged from 40 to 65 years. All were subjected to laparoscopic transgastric submucosal excision of GIST in upper two-third of the stomach with 1 cm margin having different locations in stomach...
January 2018: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/29237476/giant-gastrointestinal-stromal-tumor-with-predominantly-cystic-changes-a-case-report-and-literature-review
#14
Liying Wang, Libin Liu, Zhaohui Liu, Yueli Tian, Zhe Lin
BACKGROUND: Gastrointestinal stromal tumors (GISTs) rarely present with predominantly cystic changes. Here, we report a case of giant GIST of the stomach with predominantly cystic changes in a 74-year-old female patient. CASE PRESENTATION: The tumor was 10 cm × 15 cm in size and positive for CD117, H-caldesmon, and DOG-1. Complete surgical resection was performed without regional lymphadenectomy. The patient recovered uneventfully and no recurrence occurred...
December 13, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29207963/two-staging-systems-for-gastrointestinal-stromal-tumors-in-the-stomach-which-is-better
#15
Chul Hong Park, Gwang Ha Kim, Bong Eun Lee, Geun Am Song, Do Youn Park, Kyung Un Choi, Dae Hwan Kim, Tae Yong Jeon
BACKGROUND: The prognosis of a gastrointestinal stromal tumor (GIST) is influenced by its anatomic site; however, few studies on the prognosis of gastric GISTs have been reported. The aims of this study were to evaluate long-term prognoses of patients who underwent surgical resection for gastric GISTs and to compare the clinical efficacy of two staging systems: the National Institutes of Health (NIH) consensus criteria and the 7th Union for International Cancer Control/American Joint Committee on Cancer (UICC/AJCC) tumor-node-metastasis (TNM) staging system...
December 6, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29207774/a-diagnostic-surprise-for-a-right-iliac-fossa-mass-a-perforated-ileal-gastrointestinal-stromal-tumour
#16
J Sanjay Prakash, Anita Samraj, G Sabarish Kumar, R Vijai
Gastrointestinal Stromal Tumours (GISTs) are tumours of the gut found mostly in stomach and small intestine. The complications are Gastrointestinal (GI) bleeding, obstruction, pain and rarely perforation. We are reporting an abnormal presentation of GIST masquerading as an acute abdomen with Right Iliac Fossa (RIF) mass in 60-year-old lady. Contrast Enhanced Computed Tomography (CECT) of abdomen revealed a peripherally enhancing encapsulated abscess in RIF in close contact with base of caecum and adjacent peritonitis suggesting caecal perforation...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29175648/prognostic-significance-of-neutrophil-to-lymphocyte-ratio-in-patients-with-gastrointestinal-stromal-tumors-a-meta-analysis
#17
REVIEW
Xiao-Feng Luo, Lin-Hua Zhou
BACKGROUND: The neutrophil to lymphocyte ratio (NLR) is reported to be a prognostic factor in multiple malignancies. However, its prognostic value in patients with gastrointestinal stromal tumors (GISTs) remains controversial. This study aims to evaluate the prognostic value of preoperative NLR in GISTs. METHODS: MEDLINE, EMBASE, and, Cochrane databases were searched until February 2017. Eligible articles were defined as studies assessing the prognostic role of preoperative NLR in GISTs...
November 23, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29167690/synchronous-gists-associated-with-multiple-sporadic-tumors-a-case-report
#18
Danila Comandini, Azzurra Damiani, Alessandro Pastorino
Gastrointestinal stromal tumors (GISTs) are rare neoplasms, but they also represent the most common mesenchymal tumors of the gastrointestinal tract originating from the cell of Cajal. GIST incidence ranges around 1% of all gastrointestinal malignancies. Approximately 5% of all GISTs have a hereditary etiology. The remaining 95% of GISTs are considered sporadic events, with up to 75% of cases driven by a constitutional activation of the c-KIT proto-oncogene. GISTs are generally solitary lesions. Nonetheless, multiple sporadic GISTs can occur and present as synchronous or metachronous tumors, usually associated with familial GIST...
2017: Drugs in Context
https://www.readbyqxmd.com/read/29151288/-the-value-of-18-f-fdg-pet-ct-imaging-in-predicting-the-malignant-potential-of-gist
#19
S X Li, M D Tang, D Y Lin, D J Liu, Q H Lyu, J P Zhang, Z H Cai
Objective: To evaluate the value of (18)F-FDG PET-CT in predicting the malignant potential of Gastrointestinal Stromal Tumors (GIST). Methods: The clinical and pathological features of 31 patients with GIST confirmed by surgery or biopsy were retrospectively analyzed. The malignant potential of GIST before treatment was assessed by (18)F-FDG PET-CT. The GIST risk classification was graded according to the Standard revised by the National Institutes of Health (NIH) in 2008. The relationship between the maximal standard uptake value (SUVmax) and GIST risk classification, tumor diameter, Ki-67 index, and mitotic count were analyzed respectively...
November 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29082324/left-adrenal-tumor-disappeared-outside-a-field-of-vision-during-laparoscopic-surgery-the-true-identity-was-gastrointestinal-stromal-tumor
#20
Hiroshi Ushida, Hirofumi Goto, Satoshi Ishitoya, Hiroyuki Onishi
Background: We report a case of gastrointestinal stromal tumor (GIST) mimicking a left adrenal tumor. Case Presentation: A 62-year-old female was referred to our hospital for the treatment of left adrenal tumor of 2.8 × 2.3 cm incidentally found during her annual checkup. The preoperative diagnosis based on upper gastroscopy and imaging complete examinations was nonfunctional left adrenal tumor possessing malignant potential. Transperitoneal laparoscopic left adrenalectomy was performed. However, the tumor was not found in the excised adrenal gland that had been completely removed during surgery...
2017: Journal of Endourology Case Reports
keyword
keyword
30105
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"