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Rectal MRI

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https://www.readbyqxmd.com/read/28086856/the-addition-of-a-sagittal-image-fusion-improves-the-prostate-cancer-detection-in-a-sensor-based-mri-ultrasound-fusion-guided-targeted-biopsy
#1
Karsten Günzel, Hannes Cash, John Buckendahl, Maximilian Königbauer, Patrick Asbach, Matthias Haas, Jörg Neymeyer, Stefan Hinz, Kurt Miller, Carsten Kempkensteffen
BACKGROUND: To explore the diagnostic benefit of an additional image fusion of the sagittal plane in addition to the standard axial image fusion, using a sensor-based MRI/US fusion platform. METHODS: During July 2013 and September 2015, 251 patients with at least one suspicious lesion on mpMRI (rated by PI-RADS) were included into the analysis. All patients underwent MRI/US targeted biopsy (TB) in combination with a 10 core systematic prostate biopsy (SB). All biopsies were performed on a sensor-based fusion system...
January 13, 2017: BMC Urology
https://www.readbyqxmd.com/read/28079398/feasibility-evaluation-of-diffusion-weighted-imaging-using-an-integrated-mri-radiotherapy-system-for-response-assessment-to-neoadjuvant-therapy-in-rectal-cancer
#2
Narek Shaverdian, Yingli Yang, Peng Hu, Steven Hart, Ke Sheng, James Lamb, Minsong Cao, Nzhde Agazaryan, David Thomas, Michael Steinberg, Daniel A Low, Percy Lee
OBJECTIVES: To evaluate the feasibility of on-board DWI with an integrated low-field MRI-radiotherapy system to assess responses to neoadjuvant chemoradiation (NAC) in rectal cancer. METHODS: A spin echo-based planar imaging diffusion sequence on a 0.35 T MRI-radiotherapy system was acquired over the course of NAC. The apparent diffusion coefficients (ADC) from the tumor region of interest (ROIs) were calculated. A functional diffusion map (fDM) was created showing a pixel-wise ADC analysis of the ROI over the course of treatment...
January 12, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28073196/mri-us-fusion-prostate-biopsy-our-initial-experience
#3
Vito Lacetera, Bernardo Cervelli, Antonio Cicetti, Giuliana Gabrielloni, Michele Montesi, Roberto Morcellini, Gianni Parri, Emilio Recanatini, Gianluca Giglioni, Andrea Benedetto Galosi, Valerio Beatrici
AIM: The objective of this study is to present our initial experience with magnetic resonance imaging/ultrasound (MRI/US) fusion biopsy using the Koelis Trinity device after the first consecutive 59 patients. MATERIALS AND METHODS: 59 consecutive patients with suspected prostate cancer (PCA) underwent prostate biopsy using Trinity Koelis® (Koelis, Grenoble, France). We divided the patients into 2 groups: patients with a previous negative mapping underwent to a MRI/US fusion re-biopsy (Group A); and biopsy-naïve patients who underwent to a first stereotactic 3-D mapping of the prostate (Group B)...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28063613/why-and-where-do-we-miss-significant-prostate-cancer-with-multi-parametric-magnetic-resonance-imaging-followed-by-magnetic-resonance-guided-and-transrectal-ultrasound-guided-biopsy-in-biopsy-na%C3%A3-ve-men
#4
Martijn G Schouten, Marloes van der Leest, Morgan Pokorny, Martijn Hoogenboom, Jelle O Barentsz, Les C Thompson, Jurgen J Fütterer
BACKGROUND: Knowledge of significant prostate (sPCa) locations being missed with magnetic resonance (MR)- and transrectal ultrasound (TRUS)-guided biopsy (Bx) may help to improve these techniques. OBJECTIVE: To identify the location of sPCa lesions being missed with MR- and TRUS-Bx. DESIGN, SETTING, AND PARTICIPANTS: In a referral center, 223 consecutive Bx-naive men with elevated prostate specific antigen level and/or abnormal digital rectal examination were included...
January 4, 2017: European Urology
https://www.readbyqxmd.com/read/28059910/validation-of-mri-and-surgical-decision-making-to-predict-a-complete-resection-in-pelvic-exenteration-for-recurrent-rectal-cancer
#5
Wendy E Brown, Cherry E Koh, Tim Badgery-Parker, Michael J Solomon
BACKGROUND: The main predictor of long-term survival in patients with recurrent rectal cancer is surgical resection with a clear resection margin. MRI plays a role in patient selection and surgical planning. OBJECTIVE: This study aimed to validate MRI in determining pelvic involvement by comparing MRI to histological outcomes, to assess the effect of MRI on surgical planning by comparing MRI findings with the surgical procedure, and to compare MRI anatomical involvement with resection outcome to assess if MRI can predict a clear resection margin...
February 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28055248/review-article-functional-mri-for-quantitative-treatment-response-prediction-in-locally-advanced-rectal-cancer
#6
Trang T Pham, Gary P Liney, Karen Wong, Michael B Barton
Despite advances in multi-modality treatment strategies for locally advanced rectal cancer and improvements in loco-regional control, there is still a considerable variation in response to neo-adjuvant chemo-radiotherapy (CRT). Accurate prediction of response to neo-adjuvant CRT would enable early stratification of management according to good responders and poor responders, in order to adapt treatment to improve therapeutic outcomes in rectal cancer. Clinical studies in diffusion weighted imaging (DWI) and dynamic contrast enhanced (DCE) MRI have shown promising results for the prediction of therapeutic response in rectal cancer...
January 5, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28050622/correlation-between-quantitative-and-semiquantitative-parameters-in-dce-mri-with-a-blood-pool-agent-in-rectal-cancer-can-semiquantitative-parameters-be-used-as-a-surrogate-for-quantitative-parameters
#7
Rebecca A P Dijkhoff, Monique Maas, Milou H Martens, Nikolaos Papanikolaou, Doenja M J Lambregts, Geerard L Beets, Regina G H Beets-Tan
PURPOSE: The aim of this study was to assess correlation between quantitative and semiquantitative parameters in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in rectal cancer patients, both in a primary staging and restaging setting. MATERIALS AND METHODS: Nineteen patients were included with DCE-MRI before and/or after neoadjuvant therapy. DCE-MRI was performed with gadofosveset trisodium (Ablavar(®), Lantheus Medical Imaging, North Billerica, Massachusetts, USA)...
January 3, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28048910/su-g-jep2-10-on-the-need-for-a-dynamic-model-for-patient-specific-distortion-corrections-for-mr-only-pelvis-treatment-planning
#8
C Glide-Hurst, W Zheng, C Stehning, S Weiss, S Renisch
PURPOSE: Patient-specific distortions, particularly near tissue/air interfaces, require assessment and possible corrections for MRI-only radiation treatment planning (RTP). However, patients are dynamic due to changes in physiological status and motion during imaging sessions. This work investigated the need for dynamic patient-specific distortion corrections to support pelvis MR-only RTP. METHODS: The pelvises of healthy volunteers were imaged at 1.0T, 1.5T, and 3...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048869/su-f-j-145-mri-guided-interventional-boost-radiotherapy-for-rectal-cancer-investigating-the-feasibility-of-adapting-the-anatomy
#9
J J E Kleijnen, A M Couwenberg, B van Asselen, J J W Lagendijk, M Intven, B W Raaymakers
PURPOSE: The recent development of an MRI-linac allows adaptation of treatments to the anatomy of the moment. This anatomy, in turn, could be altered into a more favorable situation for radiotherapy purposes. The purpose of this study is to investigate the potential dosimetric benefits of manipulating rectal anatomy in MRI-guided interventional external-beam radiotherapy for rectal cancer. METHODS: For this retrospective analysis, four patients (1M/3F) diagnosed with rectal cancer were included...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047055/su-g-jep2-06-dosimetric-and-workflow-evaluation-of-first-commercial-synthetic-ct-software-for-clinical-use-in-pelvis
#10
N Tyagi, J Zhang, L Happersett, M Kadbi, J Mechalakos, J Deasy, M Hunt
PURPOSE: evaluate a commercial synthetic CT (syn-CT) software for use in prostate radiotherapy METHODS: Twenty prostate patients underwent CT and MR simulation scans in treatment position on a 3T Philips scanner. The MR protocol consisted of a T2w turbo spin-echo for soft tissue contrast, a 2D balanced-fast field echo (b-FFE) for fiducial identification, a dual-echo 3D FFE B0 map for distortion analysis and a 3D mDIXON FFE sequence to generate syn-CT. Two echoes are acquired during mDIXON scan, allowing water, fat, and in-phase images to be derived using the frequency shift of the fat and water protons...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044947/the-importance-of-preoperative-staging-of-rectal-cancer-using-ultiparametric-mri-part-ii-tnm-cancer-staging
#11
Ferdinand Bauer
No abstract text is available yet for this article.
November 2016: Chirurgia
https://www.readbyqxmd.com/read/28042958/standardized-index-of-shape-dce-mri-and-standardized-uptake-value-pet-ct-two-quantitative-approaches-to-discriminate-chemo-radiotherapy-locally-advanced-rectal-cancer-responders-under-a-functional-profile
#12
Antonella Petrillo, Roberta Fusco, Mario Petrillo, Vincenza Granata, Paolo Delrio, Francesco Bianco, Biagio Pecori, Gerardo Botti, Fabiana Tatangelo, Corradina Caracò, Luigi Aloj, Antonio Avallone, Secondo Lastoria
PURPOSE: To investigate dynamic contrast enhanced-MRI (DCE-MRI) in the preoperative chemo-radiotherapy (CRT) assessment for locally advanced rectal cancer (LARC) compared to18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). METHODS: 75 consecutive patients with LARC were enrolled in a prospective study. DCE-MRI analysis was performed measuring SIS: linear combination of percentage change (Δ) of maximum signal difference (MSD) and wash-out slope (WOS)...
December 22, 2016: Oncotarget
https://www.readbyqxmd.com/read/28027737/diffusion-mri-for-rectal-cancer-staging-adc-measurements-before-and-after-ultrasonographic-gel-lumen-distension
#13
S Palmucci, M Piccoli, S Piana, P V Foti, R O A Siverino, L A Mauro, P Milone, G C Ettorre
OBJECTIVES: To compare Apparent Diffusion Coefficient (ADC) measurements in rectal neoplastic lesions before and after lumen distension obtained with sonography transmission gel. METHODS: From January 2014 to July 2016, 25 patients (average age 63.7, range 41-85, 18 males) were studied for pre-treatment rectal cancer staging using a 1.5T MRI. Diffusion MRI was obtained using echo-planar imaging with b=800 value; all patients were studied acquiring diffusion sequences with and without rectal lumen distension obtained using sonography transmission gel...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28025227/rectal-cancer-restaging-using-3d-cube-vs-2d-t2-weighted-technique-after-neoadjuvant-therapy-a-diagnostic-study
#14
Wuteng Cao, Yanbang Lian, Dechao Liu, Fangqian Li, Pan Zhu, Zhiyang Zhou
OBJECTIVE: This study aimed to compare the accuracy of rectal cancer restaging after neoadjuvant therapy with 3D CUBE sequence with 2D T2-weighted fast spin-echo (FSE) sequence. METHODS: This retrospective study comprised 72 patients with rectal cancer confirmed by colonoscopy and biopsy. After neoadjuvant therapy, all patients underwent pelvic magnetic resonance imaging (MRI) examination at 1.5T MRI sequences including a single coronal 3D CUBE T2-weighted FSE sequence with 1...
December 26, 2016: Gastroenterology Report
https://www.readbyqxmd.com/read/28011494/mmri-at-3-0-t-as-an-evaluation-tool-of-therapeutic-response-to-neoadjuvant-crt-in-patients-with-advanced-stage-rectal-cancer
#15
Ulrike I Attenberger, Melissa M Ong, Nils Rathmann, Fabian Doyon, Peter Kienle, Ralf-Dieter Hofheinz, Lothar R Pilz, Dietmar J Dinter, Stefan O Schoenberg, Daniel Hausmann
AIM: To assess whether multiparametric MRI (mMRI) can serve as a tool for evaluating response to chemoradiation therapy (CRT) in advanced-stage rectal cancer. PATIENTS AND METHODS: Twenty-one patients underwent a mMRI protocol at 3T before and after CRT. Two experienced radiologists evaluated the MRI measurements and inter-reader correlation was assessed. Changes in functional parameters in relation to regression, as well as pT stage were analyzed. The perfusion parameters plasma flow (PF) and mean transit time (MTT) were calculated offline using the established UMM Perfusion tool...
January 2017: Anticancer Research
https://www.readbyqxmd.com/read/28009094/clinical-value-of-mri-detected-extramural-venous-invasion-in-rectal-cancer
#16
REVIEW
Pratik Tripathi, Sheng Xiang Rao, Meng Su Zeng
OBJECTIVE: This study highlights the importance of MRI-detected EMVI (mrEMVI) before and after rectal cancer treatment. In addition, it analyzes the prognostic correlation between mrEMVI and circulating tumor cells (CTCs) in rectal cancer. METHODS AND MATERIALS: We reviewed literature in English from 1981 to 2016 on Medline (Ovid), Embase (Ovid), and Cochrane. Keywords used in the literature search were as follows: magnetic resonance imaging/MRI; extramural venous invasion/EMVI; rectal cancer; CTC; colorectal cancer...
December 23, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28004138/investigation-of-volumetric-apparent-diffusion-coefficient-histogram-analysis-for-assessing-complete-response-and-clinical-outcomes-following-pre-operative-chemoradiation-treatment-for-rectal-carcinoma
#17
Vijay Chidambaram, James D Brierley, Bernard Cummings, Rajesh Bhayana, Ravi J Menezes, Erin D Kennedy, Richard Kirsch, Kartik S Jhaveri
PURPOSE: To investigate the relationship of pre-treatment volumetric apparent diffusion coefficient (ADC) histogram parameters with post-operative histopathologic treatment response and clinical outcomes following pre-operative chemoradiation treatment (CRT) in rectal cancer. MATERIALS AND METHODS: In a Health Insurance Portability and Accountability Act compliant retrospective study, 78 rectal cancer patients treated with pre-operative CRT and rectal MRI were included...
December 21, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/28002822/the-vegfr-inhibitor-cediranib-improves-the-efficacy-of-fractionated-radiotherapy-in-a-colorectal-cancer-xenograft-model
#18
Elodie Melsens, Bert Verberckmoes, Natacha Rosseel, Christian Vanhove, Benedicte Descamps, Piet Pattyn, Wim Ceelen
BACKGROUND/PURPOSE: Radiotherapy (RT) increases local tumor control in locally advanced rectal cancer, but complete histological response is seen in only a minority of cases. Antiangiogenic therapy has been proposed to improve RT efficacy by "normalizing" the tumor microvasculature. Here, we examined whether cediranib, a pan-vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor, improves microvascular function and tumor control in combination with RT in a mouse colorectal cancer (CRC) model...
December 22, 2016: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/28002239/feasibility-of-multiparametric-magnetic-resonance-imaging-of-the-prostate-at-7-t
#19
Miriam W Lagemaat, Bart W J Philips, Eline K Vos, Mark J van Uden, Jurgen J Fütterer, Sjoerd F Jenniskens, Tom W J Scheenen, Marnix C Maas
OBJECTIVES: The aim of this study was to evaluate the technical feasibility of prostate multiparametric magnetic resonance imaging (mpMRI) at a magnetic field strength of 7 T. MATERIALS AND METHODS: In this prospective institutional review board-approved study, 14 patients with biopsy-proven prostate cancer (mean age, 65.2 years; median prostate-specific antigen [PSA], 6.2 ng/mL), all providing signed informed consent, underwent 7 T mpMRI with an external 8-channel body-array transmit coil and an endorectal receive coil between September 2013 and October 2014...
December 20, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/28001320/dynamic-multi-echo-dce-and-dsc-mri-in-rectal-cancer-low-primary-tumor-k-trans-and-%C3%AE-r2-peak-are-significantly-associated-with-lymph-node-metastasis
#20
Endre Grøvik, Kathrine Røe Redalen, Tryggve Holck Storås, Anne Negård, Stein Harald Holmedal, Anne Hansen Ree, Sebastian Meltzer, Atle Bjørnerud, Kjell-Inge Gjesdal
PURPOSE: To implement a dynamic contrast-based multi-echo MRI sequence in assessment of rectal cancer and evaluate associations between histopathologic data and the acquired dynamic contrast-enhanced (DCE) and dynamic susceptibility contrast (DSC) -MRI parameters. MATERIALS AND METHODS: This pilot study reports results from 17 patients with resectable rectal cancer. Dynamic contrast-based multi-echo MRI (1.5T) was acquired using a three-dimensional multi-shot EPI sequence, yielding both DCE- and DSC-data following a single injection of contrast agent...
December 21, 2016: Journal of Magnetic Resonance Imaging: JMRI
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