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Rectal MRI

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https://www.readbyqxmd.com/read/29137613/preoperative-t-staging-using-ct-colonography-with-multiplanar-reconstruction-for-very-low-rectal-cancer
#1
Dai Shida, Gen Iinuma, Akira Komono, Hiroki Ochiai, Shunsuke Tsukamoto, Mototaka Miyake, Yukihide Kanemitsu
BACKGROUND: Preoperative T staging of lower rectal cancer is an important criterion for selecting intersphincteric resection (ISR) or abdominoperineal resection (APR) as well as selecting neoadjuvant therapy. The aim of this study was to evaluate the accuracy of preoperative T staging using CT colonography (CTC) with multiplanar reconstruction (MPR), in which with the newest workstation the images can be analyzed with a slice thickness of 0.5 mm. METHODS: Between 2011 and 2013, 45 consecutive patients with very low rectal adenocarcinoma underwent CTC with MPR...
November 14, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29130229/-discovery-anatomy-and-clinical-significance-of-the-mesorectal-finish-line-of-total-mesorectal-excision
#2
Pan Chi, Xiaojie Wang, Guoxian Guan, Huiming Lin, Ying Huang, Weizhong Jiang
OBJECTIVE: To investigate the surgical endpoint of separation of mesorectum during total mesorectal excision (TME), suggesting the concept of "terminal line", in order to perform above separation better for middle-low rectal cancer. METHODS: Gross anatomy of mesorectum endpoint from 81 surgical specimens of low anterior resection (LAR, 5 to 6 cm of distance from low margin of cancer to anal edge) and 71 surgical specimens of abdominal perineal resection(APR, <5 cm of distance from low margin of cancer to anal edge) was observed...
October 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29127435/intensified-preoperative-chemoradiation-by-adding-oxaliplatin-in-locally-advanced-primary-operable-ct3nxm0-rectal-cancer-impact-on-long-term-outcome-results-of-the-phase%C3%A2-ii-tako-05-abcsg-r%C3%A2-02-trial
#3
P Kogler, A F DeVries, W Eisterer, J Thaler, L Sölkner, D Öfner
PURPOSE: The major goals of preoperative treatment for locally advanced rectal cancers (LARCs) are improvement of local tumor control, tumor downsizing, and downstaging. Modifications with respect to standardized chemoradiation protocol, e. g., integrating oxaliplatin, are realized with the aim of improving primary tumor response and patient outcome. PATIENTS AND METHODS: In this phase II multicenter study, patients with LARC of the mid- or lower rectum, cT3cNxcM0 as staged by MRI, were included and treated preoperatively with a combination of capecitabine and oxaliplatin following a standardized protocol during radiation...
November 10, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29126575/validation-of-prostate-imaging-reporting-and-data-system-version-2-a-retrospective-analysis
#4
Michael Nguyentat, Alexander Ushinsky, Alessandra Miranda-Aguirre, Edward Uchio, Chandana Lall, Layla Shirkhoda, Thomas Lee, Christopher Green, Roozbeh Houshyar
PURPOSE: Use of magnetic resonance imaging (MRI)/transrectal ultrasound fusion biopsies to determine the accuracy of multiparametric MRI (mpMRI), using Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2), for detecting clinically significant prostate cancer in the overall gland and specifically the peripheral zone (PZ) and transitional zone (TZ). METHODS: A retrospective analysis of patients who underwent fusion biopsy identified 137 men with 231 prostate lesions was approved by the Institutional Review Board...
October 12, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29120661/rectal-cancer-confined-to-the-bowel-wall-the-role-of-3-tesla-phased-array-mr-imaging-in-t-categorization
#5
Hale Çolakoğlu Er, Elif Peker, Ayşe Erden, İlhan Erden, Ethem Geçim, Berna Savaş
OBJECTIVE: To determine the diagnostic value of 3 Tesla MR imaging in detection of mucosal (Tis), submucosal (T1), and muscularis propria (T2) invasion in patients with early rectal cancer. METHODS: A total of 50 consecutive patients who underwent 3 Tesla MR imaging and curative-intent intervention for MRI-staged Tis/T1/T2 rectal cancer from March 2012 to December 2016 were included. The radiologic T category of each rectal tumor were compared retrospectively with histopathologic results assessed according to the TNM classification...
November 9, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29113193/value-of-endorectal-ultrasonography-in-measuring-the-extent-of-mesorectal-invasion-and-substaging-of-t3-stage-rectal-cancer
#6
Guangxi Zhong, Yi Xiao, Weixun Zhou, Weidong Pan, Qingli Zhu, Jing Zhang, Yuxin Jiang
The present study aimed to determine the value of endorectal ultrasound (ERUS) and magnetic resonance imaging (MRI) for T3 rectal cancer, and substaging of T3 rectal cancer by measuring the extent of mesorectal invasion (EMI). The clinical data of patients with rectal cancer who were admitted to the general surgical department of Peking Union Medical College Hospital (Beijing, China) were reviewed and analyzed. Two ultrasound practitioners independently measured the EMI on ERUS, and a radiologist measured the EMI on MRI...
November 2017: Oncology Letters
https://www.readbyqxmd.com/read/29112469/risk-of-clinically-significant-prostate-cancer-associated-with-prostate-imaging-reporting-and-data-system-category-3-equivocal-lesions-identified-on-multiparametric-prostate-mri
#7
Alison D Sheridan, Sameer K Nath, Jamil S Syed, Sanjay Aneja, Preston C Sprenkle, Jeffrey C Weinreb, Michael Spektor
OBJECTIVE: The objective of this study is to determine the frequency of clinically significant cancer (CSC) in Prostate Imaging Reporting and Data System (PI-RADS) category 3 (equivocal) lesions prospectively identified on multiparametric prostate MRI and to identify risk factors (RFs) for CSC that may aid in decision making. MATERIALS AND METHODS: Between January 2015 and July 2016, a total of 977 consecutively seen men underwent multiparametric prostate MRI, and 342 underwent MRI-ultrasound (US) fusion targeted biopsy...
November 7, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29110729/penile-metastasis-from-rectal-adenocarcinoma-a-case-report
#8
Boubacar Efared, Gabrielle Atsame Ebang, Soufiane Tahirou, Layla Tahiri, Ibrahim Sory Sidibé, Fatimazahra Erregad, Aboubakry Sow, Nawal Hammas, Moulay H Farih, Laila Chbani, Hinde El Fatemi
BACKGROUND: Despite its rich vasculature, the penis is rarely involved by metastasis. Since the first description of penile metastasis in 1870, fewer than 500 cases have been reported in the literature. The pelvic organs are the main source of primary tumors that metastasize to the penis. CASE PRESENTATION: We report a case of a 46-year-old Arabic man who presented with erectile dysfunction and painful induration of the penile root. Eight months ago, he had undergone abdomino-perineal resection for rectal adenocarcinoma after neo-adjuvant chemotherapy...
November 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29102740/clinical-outcomes-with-mri-guided-image-based-brachytherapy-in-cervical-cancer-an-institutional-experience
#9
Vijai Simha, Bhavana Rai, Firuza D Patel, Rakesh Kapoor, Suresh C Sharma, Oinam A Singh, Veenu Singla, Bhaswanth Dhanireddy, Sushmita Ghoshal
PURPOSE: To evaluate the long-term disease control and toxicity to the organs at risk after dose-escalated image-based adaptive brachytherapy (BT) in cervical cancer. METHODS AND MATERIALS: Sixty patients of cervical cancer were treated with external radiotherapy 46 Gy in 23 fractions with weekly cisplatin and MRI-guided BT 7 Gy × 4 fractions with a minimum dose of 85.7 Gy (EQD2) to the high-risk clinical target volume (HRCTV). The BT dose was initially prescribed to point A and plans were optimized to ensure coverage of both point A and HRCTV while maintaining doses to the organs at risk within the recommended constraints...
November 1, 2017: Brachytherapy
https://www.readbyqxmd.com/read/29102233/rectal-perfusion-parameters-normalised-to-tumour-free-rectal-wall-can-predict-response-to-neoadjuvant-chemoradiotherapy
#10
S Krishan, A Patel, R Sud, R Puri, A Vaid, L Lipi, T Kataria
AIMS: To evaluate absolute changes in quantitative and semi-quantitative perfusion parameters using a newer approach of comparing these parameters with tumour-free normal rectal wall (i.e., relative/normalised change) in predicting complete pathological response to chemoradiotherapy. MATERIALS AND METHODS: Perfusion parameters measured before and after treatment of 10 patients with histopathologically proven rectal cancer that showed complete treatment response (Group 1) were compared with 10 patients with residual tumour on histopathology following treatment (Group 2)...
October 25, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29100742/outcome-of-neoadjuvant-chemoradiation-in-mri-staged-locally-advanced-rectal-cancer-retrospective-analysis-of-123-chinese-patients
#11
Shing Fung Lee, Chi Leung Chiang, Francis Ann Shing Lee, Yiu Wah Wong, Chi Ming Poon, Frank Chi Sing Wong, Stewart Yuk Tung
BACKGROUND: For advanced rectal cancer with involved or threatened mesorectal fascia (MRF), current standard is pre-operative long course chemoradiotherapy (PLCRT) with either capecitabine or 5-fluorouracil (5-FU). However, few Chinese data on its clinical outcome are available, especially for those with pelvic MRI staging. METHODS: Between Jan-2009 and Oct-2014, 123 consecutive patients with biopsy proven adenocarcinoma of rectum, all with pelvic MRI staging, selected for PLCRT after multi-disciplinary team discussion were recruited...
November 1, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29094851/prospective-nonrandomized-study-of-diagnostic-accuracy-comparing-prostate-cancer-detection-by-transrectal-ultrasound-guided-biopsy-to-magnetic-resonance-imaging-with-subsequent-mri-guided-biopsy-in-biopsy-na%C3%A3-ve-patients
#12
Roberto Castellucci, Ana I Linares Quevedo, Francisco J Sánchez Gómez, Jesús Díez Rodríguez, Leopoldo Cogorno, Isidro Cogollos Acuña, Isabel Salmerón Béliz, Marta Muñoz Fernández de Legaría, Luis Martínez Piñeiro
BACKGROUND: To evaluate the diagnostic efficacy in cancer prostate (PCa) of Multiparametric prostate magnetic resonance imaging (mp-MRI) targeted biopsy compared to standard systematic transrectal ultrasound-guided biopsy (TRUSGB) in biopsy-naïve patients. METHODS: A total of 168 biopsy-naïve men with clinical suspicion of PCa due to elevated PSA levels and/or an abnormal digital rectal examination were consecutively enrolled from July 2011 to July 2014. All patients underwent TRUSGB...
December 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29072488/t3-sub-classification-using-the-emd-mesorectum-ratio-predicts-neoadjuvant-chemoradiation-outcome-in-t3-rectal-cancer-patients
#13
Lijun Shen, Yiqun Sun, Hui Zhang, Jing Zhang, Weijuan Deng, Yaqi Wang, Ye Yao, Lifeng Yang, Ji Zhu, Tong Tong, Liping Liang, Zhen Zhang
PURPOSE: To evaluate the feasibility of the EMD (extramural depth)/mesorectum ratio as a marker for T3 rectal cancer and its ability to predict tumor response to neoadjuvant chemoradiation and survival. METHODS: From 2010 to 2016, 284 T3 rectal cancer patients who underwent high resolution MRI before neoadjuvant chemoradiation were enrolled. The EMD was defined as the distance from the outer edge of the muscularis propria to the outermost edge of the tumor. The measurement of the tumor EMD and mesorectum was in the same layer and their ratio was calculated...
October 26, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29063250/whole-tumour-diffusion-kurtosis-mr-imaging-histogram-analysis-of-rectal-adenocarcinoma-correlation-with-clinical-pathologic-prognostic-factors
#14
Yanfen Cui, Xiaotang Yang, Xiaosong Du, Zhizheng Zhuo, Lei Xin, Xintao Cheng
OBJECTIVE: To investigate potential relationships between diffusion kurtosis imaging (DKI)-derived parameters using whole-tumour volume histogram analysis and clinicopathological prognostic factors in patients with rectal adenocarcinoma. MATERIAL AND METHODS: 79 consecutive patients who underwent MRI examination with rectal adenocarcinoma were retrospectively evaluated. Parameters D, K and conventional ADC were measured using whole-tumour volume histogram analysis...
October 23, 2017: European Radiology
https://www.readbyqxmd.com/read/29052070/the-feasibility-of-laparoscopic-rectal-resection-in-patients-undergoing-reoperation-after-transanal-endoscopic-microsurgery-tem
#15
M Ortenzi, R Ghiselli, A Paolucci, M Guerrieri
BACKGROUND: The success of transanal endoscopic microsurgery (TEM) for early rectal cancer depends on proper indications and strict patient selection. When unfavorable pathologic features are identified after TEM operation, total mesorectal excision is recommended to minimize the risk of recurrence. In this study, data were collected in a retrospective series of patients to determine the results of laparoscopic reoperation after TEM. METHODS: All patients underwent an accurate rectal-digital examination and clinical tumor staging by transanal endosonography, CT, and/or MRI...
October 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29043428/magnetic-resonance-imaging-for-clinical-management-of-rectal-cancer-updated-recommendations-from-the-2016-european-society-of-gastrointestinal-and-abdominal-radiology-esgar-consensus-meeting
#16
Regina G H Beets-Tan, Doenja M J Lambregts, Monique Maas, Shandra Bipat, Brunella Barbaro, Luís Curvo-Semedo, Helen M Fenlon, Marc J Gollub, Sofia Gourtsoyianni, Steve Halligan, Christine Hoeffel, Seung Ho Kim, Andrea Laghi, Andrea Maier, Søren R Rafaelsen, Jaap Stoker, Stuart A Taylor, Michael R Torkzad, Lennart Blomqvist
OBJECTIVES: To update the 2012 ESGAR consensus guidelines on the acquisition, interpretation and reporting of magnetic resonance imaging (MRI) for clinical staging and restaging of rectal cancer. METHODS: Fourteen abdominal imaging experts from the European Society of Gastrointestinal and Abdominal Radiology (ESGAR) participated in a consensus meeting, organised according to an adaptation of the RAND-UCLA Appropriateness Method. Two independent (non-voting) Chairs facilitated the meeting...
October 17, 2017: European Radiology
https://www.readbyqxmd.com/read/29025845/a-multicentre-randomised-controlled-trial-assessing-whether-mri-targeted-biopsy-is-non-inferior-to-standard-transrectal-ultrasound-guided-biopsy-for-the-diagnosis-of-clinically-significant-prostate-cancer-in-men-without-prior-biopsy-a-study-protocol
#17
Veeru Kasivisvanathan, Fatima Jichi, Laurence Klotz, Arnauld Villers, Samir S Taneja, Shonit Punwani, Alex Freeman, Mark Emberton, Caroline M Moore
INTRODUCTION: The classical pathway for the diagnosis of prostate cancer is transrectal ultrasound-guided (TRUS) biopsy of the prostate initiated on the basis of a raised prostate-specific antigen (PSA). An alternative pathway is to perform multi-parametricMRI (MPMRI) to localise cancer and to use this information to influence the decision for, and conduct of, a subsequent biopsy, known as an MPMRI-targeted biopsy. An MPMRI pathway has been shown to detect a similar or greater amount of clinically significant cancer as TRUS biopsy but has several advantages, including the potential to biopsy fewer men with fewer cores...
October 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29022282/analysis-of-five-cases-of-human-herpesvirus-6-myelitis-among-121-cord-blood-transplantations
#18
Toshimitsu Ueki, Kenichi Hoshi, Yuki Hiroshima, Masahiko Sumi, Naoaki Ichikawa, Masao Ogata, Takako Satou, Takahiro Fukuda, Hikaru Kobayashi
Reports of myelitis associated with human herpesvirus-6 (HHV-6) following allogeneic transplantation are rare. Of 121 cases of cord blood transplantation (CBT) performed at Nagano Red Cross Hospital, five cases (4.1%) of HHV-6 myelitis developed at around the time of engraftment. The major symptom identified in all five patients was superficial pain or pruritus linked to segmental levels of the spinal cord. Other identified symptoms were fever or low-grade fever in all five patients, autonomic nerve disorder in four patients, bladder and rectal disturbance in two patients, and extrapyramidal disorder in two patients...
October 11, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/28991083/prediction-of-n0-irradiated-rectal-cancer-comparing-mri-before-and-after-preoperative-chemoradiotherapy
#19
COMPARATIVE STUDY
Fabio Pomerri, Filippo Crimì, Nicola Veronese, Alessandro Perin, Carmelo Lacognata, Francesca Bergamo, Caterina Boso, Isacco Maretto
BACKGROUND: The prediction of lymph node status using MRI has an impact on the management of rectal cancer, both before and after preoperative chemoradiotherapy. OBJECTIVE: The purpose of this study was to maximize the negative predictive value and sensitivity of mesorectal lymph node imaging after chemoradiotherapy because postchemoradiation node-negative patients may be treated with rectum-sparing approaches. DESIGN: This was a retrospective study...
November 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28987662/value-of-dce-mri-for-staging-and-response-evaluation-in-rectal-cancer-a-systematic-review
#20
REVIEW
Rebecca A P Dijkhoff, Regina G H Beets-Tan, Doenja M J Lambregts, Geerard L Beets, Monique Maas
PURPOSE: Aim was to perform a systematic review to evaluate the clinical value of dynamic contrast-enhanced (DCE) MRI in rectal cancer. METHODS AND MATERIALS: A systematic search was performed on Pubmed, Embase and the Cochrane library. Studies that evaluated DCE-MRI for tumour aggressiveness, primary staging and restaging after chemoradiation (CRT) were included. Information on population, DCE technique, DCE parameters and outcome (angiogenesis, staging and response) were extracted...
October 2017: European Journal of Radiology
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