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https://www.readbyqxmd.com/read/27908678/avoidance-of-late-rectal-toxicity-after-high-dose-rate-brachytherapy-boost-treatment-for-prostate-cancer
#1
Borut Kragelj, Jernej Zlatic, Lijana Zaletel-Kragelj
PURPOSE: To elucidate potential risk factors important for the appearance of late rectal toxicity (LRT) after high-dose-rate boost treatment (HDRBT) of prostate cancer and to validate the predictive value of the minimal dose to the most exposed 2 cc of rectum received with HDRBT (D2ccrect). METHODS AND MATERIALS: The study of LRT, defined as relative deterioration of defecation problems (RDDP) (stool frequency, pain, rectal bleeding, fecal urgency, and incontinence) during follow-up period, was carried out on 88 patients, consecutively treated from October 2006 through April 2011 with HDRBT of 3 × 6-7 Gy to 50-50...
November 28, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27898453/resolution-of-rectal-prolapse-by-vaginal-reconstruction
#2
Hemikaa Devakumar, Neeraja Chandrasekaran, Alexandriah Alas, Laura Martin, G Willy Davila, Eric Hurtado
BACKGROUND: Rectal prolapse is a disorder of the pelvic floor in which the layers of the rectal mucosa protrude outward through the anus. Surgical repair is the mainstay of treatment. Options include intra-abdominal procedures such as rectopexy and perineal procedures such as the Delorme and Altemeier perineal rectosigmoidectomy. Rectal and vaginal prolapse can often coexist. However, to our knowledge, there are no reported cases of rectal prolapse resolved by the repair of a compressive enterocele abutting the anterior rectal wall through a vaginal approach alone...
November 28, 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27895682/development-and-clinical-implementation-of-a-new-template-for-mri-based-intracavitary-interstitial-gynecologic-brachytherapy-for-locally-advanced-cervical-cancer-from-ct-based-mupit-to-the-mri-compatible-template-benidorm-ten-years-of-experience
#3
Silvia Rodríguez Villalba, Jose Richart Sancho, Antonio Otal Palacín, Jose Perez-Calatayud, Manuel Santos Ortega
PURPOSE: To study outcome and toxicity in 59 patients with locally advanced cervix carcinoma treated with computed tomography (CT)-based Martinez universal perineal interstitial template (MUPIT) and the new magnetic resonance imaging (MRI)-compatible template Benidorm (TB). MATERIAL AND METHODS: From December 2005 to October 2015, we retrospectively analyzed 34 patients treated with MUPIT and 25 treated with the TB. Six 4 Gy fractions were prescribed to the clinical target volume (CTV) combined with external beam radiotherapy (EBRT)...
October 2016: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/27885389/mri-features-of-perianal-fistulas-is-there-a-difference-between-crohn-s-and-non-crohn-s-patients
#4
Irai S Oliveira, Aoife Kilcoyne, Melissa C Price, Mukesh Harisinghani
PURPOSE: Though perianal fistulas are commonly seen in patients with Crohn's disease, they can also be seen in patients without inflammatory bowel disease. The purpose of this study was to evaluate MR imaging differences of perianal fistulas in patients with and without Crohn's disease. METHODS: Our retrospective search from January 2012 to December 2015 of the Radiology database for perianal fistula yielded 207 patients. Only patients with dedicated MR fistula protocol studies were included, whereas patients with previous anal surgery or anastomosis, anorectal tumors, and equivocal findings that could not be definitely assessed as a fistula were excluded...
November 24, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27883254/the-degree-of-extramural-spread-of-t3-rectal-cancer-an-appeal-to-the-ajcc
#5
R Zinicola, G Pedrazzi, N Haboubi, R J Nicholls
AIM: The T3 category of the TNM classification includes over 60% of all rectal tumours and encompasses the greatest variance in cancer specific end points than any other T category. The most recent edition of the cancer staging handbook of the American Joint Committee on Cancer (AJCC) (1) dated 2010 does not divide T3 tumours into subgroups which reflect cancer specific outcome more sensitively. The original aim of the present study was to review the literature to assess the influence of the degree of extramural extent of T3 rectal cancer on local recurrence and survival...
November 24, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27881048/accuracy-of-pre-treatment-locoregional-rectal-cancer-staging-in-a-national-improvement-project
#6
Bart Op de Beeck, Peter Smeets, Freddy Penninckx, Piet Pattyn, Geert Silversmit, Elizabeth Van Eycken
BACKGROUND: The aim of this study was to assess the accuracy, particularly the predictive value, of locoregional clinical rectal cancer staging (cTN) and its variability in a national improvement project. METHODS: cTN stages and the distance between tumour and mesorectal fascia (MRF) were compared with histopathological findings in 1168 patients who underwent radical resection without neoadjuvant treatment. Data were registered prospectively from 2006 to 2014. RESULTS: Agreement between clinical and histopathological TN stages was 50%, independent of tumour location...
November 24, 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27876378/toxicities-and-dose-volume-histogram-parameters-of-mri-based-brachytherapy-for-cervical-cancer
#7
Youngkyong Kim, Yeon-Joo Kim, Joo-Young Kim, Young Kyung Lim, Chiyoung Jeong, Jonghwi Jeong, Meyoung Kim, Myong Cheol Lim, Sang-Soo Seo, Sang-Yoon Park
PURPOSE: To analyze the toxicities and dose-volume histogram parameters of external-beam and magnetic resonance imaging-based intracavitary brachytherapy in cervical cancer patients. METHODS AND MATERIALS: Acute and late toxicities were assessed in 135 patients divided into four groups: group 1, grade 0; group 2, grades 1-4; group 3, grades 0-1; and group 4, grades 2-4. The doses at the International Commission on Radiation Units and Measurements (DICRU) and minimum doses to the most exposed 0...
November 18, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27872117/protocol-for-a-multicentre-randomised-feasibility-trial-evaluating-early-surgery-alone-in-low-rectal-cancer-sailor
#8
Dean A Harris, Kymberley Thorne, Hayley Hutchings, Saiful Islam, Gail Holland, Olivia Hatcher, Sarah Gwynne, Ian Jenkins, Peter Coyne, Michael Duff, Melanie Feldman, Des C Winter, Simon Gollins, Phil Quirke, Nick West, Gina Brown, Deborah Fitzsimmons, Alan Brown, John Beynon
INTRODUCTION: There are 11 500 rectal cancers diagnosed annually in the UK. Although surgery remains the primary treatment, there is evidence that preoperative radiotherapy (RT) improves local recurrence rates. High-quality surgery in rectal cancer is equally important in minimising local recurrence. Advances in MRI-guided prediction of resection margin status and improvements in abdominoperineal excision of the rectum (APER) technique supports a reassessment of the contribution of preoperative RT...
November 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27870169/comparison-of-dynamic-magnetic-resonance-defecography-with-rectal-contrast-and-conventional-defecography-for-posterior-pelvic-floor-compartment-prolapse
#9
Jan J van Iersel, Hendrik A Formijne Jonkers, Paul M Verheijen, Ivo A M J Broeders, Ben G F Heggelman, Vicknesh Sreetharan, Jurgen J Fütterer, Inne Somers, Marloes van der Leest, Esther C J Consten
AIM: The study compared the diagnostic capabilities of dynamic magnetic resonance defecography (D-MRI) with conventional defecography (CD, reference standard) in patients with symptoms of prolapse of the posterior compartment of the pelvic floor. METHOD: Forty-five consecutive patients underwent CD and D-MRI. Outcome measures were the presence or absence of rectocele, enterocele, intussusception, rectal prolapse and the descent of the anorectal junction on straining measured in millimetres...
November 21, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27865742/internal-rectal-prolapse-definition-assessment-and-management-in-2016
#10
L Cariou de Vergie, A Venara, E Duchalais, E Frampas, P A Lehur
Internal rectal prolapse (IRP) is a well-recognized pelvic floor disorder mainly seen during defecatory straining. The symptomatic expression of IRP is complex, encompassing fecal continence (56%) and/or evacuation disorders (85%). IRP cannot be characterized easily by clinical examination alone and the emergence of dynamic defecography (especially MRI) has allowed a better comprehension of its pathophysiology and led to the proposition of a severity score (Oxford score) that can guide management. Decision for surgical management should be multidisciplinary, discussed after a complete work-up, and only after medical treatment has failed...
November 16, 2016: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/27865145/rectal-gastrointestinal-stromal-tumor-with-metastasis-to-the-penis-case-report-and-review-of-literature
#11
Jacob Carlson, Wilson Alobuia, Jason Mizell
We report the case of a 51-year-old gentleman with previously diagnosed gastrointestinal stromal tumor (GIST) of the rectum with metastasis to the penis. The patient underwent abdominoperineal resection of the primary tumor with negative margins and completed a three-year course of imatinib mesylate (Gleevec). Forty months after resection of his rectal tumor, the patient presented to his urologist with worsening testicular pain, mild lower urinary tract obstructive symptoms, and nocturia. A pelvic MRI revealed the presence of an ill-defined mass in the right perineum extending from the base of the penis to the penoscrotal junction...
November 9, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27863343/acrometastasis-following-colorectal-cancer-a-case-report-and-review-of-literature
#12
Kozar Agha, Khalid Akbari, Syed Husain Abbas, Simon Middleton, Daniel McGrath
INTRODUCTION: Colorectal cancer commonly metastasises to the liver, peritoneum and lungs. Bony metastases are uncommon in colorectal cancer and in particular metastases to the hands or feet (acrometastasis) are an extremely rare occurrence. CASE PRESENTATION: A 65-year-old male with a colonic malignancy underwent elective anterior resection. Intra-operatively he was found to have a pelvic collection necessitating an end colostomy. Histology confirmed complete Dukes B tumour excision with no evidence of lymph node metastases...
November 10, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27861230/structured-reporting-of-rectal-magnetic-resonance-imaging-in-suspected-primary-rectal-cancer-potential-benefits-for-surgical-planning-and-interdisciplinary-communication
#13
Dominik Nörenberg, Wieland H Sommer, Wolfgang Thasler, Jan DʼHaese, Markus Rentsch, Thomas Kolben, Andreas Schreyer, Carsten Rist, Maximilian Reiser, Marco Armbruster
OBJECTIVES: The aim of this study was to evaluate the effect of structured reports (SRs) in comparison to nonstructured, free-text (FT) rectal magnetic resonance imaging (MRI) reports in patients with histologically proven rectal cancer and potential effects of both types of reporting on referring surgeons' satisfaction, interdisciplinary communication, and further clinical decision making. MATERIALS AND METHODS: The institutional review board approved this retrospective study with waiver of informed consent...
November 17, 2016: Investigative Radiology
https://www.readbyqxmd.com/read/27858916/evaluating-rectal-tumor-staging-with-magnetic-resonance-imaging-computed-tomography-and-endoluminal-ultrasound-a-meta-analysis
#14
Xiao-Ting Li, Xiao-Yan Zhang, Ying-Shi Sun, Lei Tang, Kun Cao
BACKGROUND: Magnetic resonance imaging (MRI), endoluminal ultrasound (EUS), and computed tomography (CT) are commonly used imaging tools to evaluate rectal tumor staging, but there was no recent meta-analysis to define the present role of the 3 tools. Here, we proposed to systematically compare the accuracy of the 3 imaging tools for rectal tumor staging. METHODS: We systematically searched diagnostic accuracy studies of MRI, CT, or EUS on rectal cancer staging, written in English or Chinese, published between January 1, 2003 and Dec 31, 2015 from database of PubMed, EMBASE, and Cochrane Library...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27845566/the-potential-predictive-value-of-mri-and-pet-ct-in-mucinous-and-nonmucinous-rectal-cancer-to-identify-patients-at-high-risk-of-metastatic-disease
#15
Brunella Barbaro, Lucia Leccisotti, Fabio M Vecchio, Marialuisa Di Matteo, Teresa Serra, Marco Salsano, Andrea Poscia, Claudio Coco, Roberto Persiani, Sergio Alfieri, Maria Antonietta Gambacorta, Vincenzo Valentini, Alessandro Giordano, Lorenzo Bonomo
OBJECTIVES: To correlate imaging parameters from baseline magnetic resonance imaging (MRI)-diffusion-weighted imaging (DWI) and -2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography-computed tomography (PET-CT) with synchronous and metachronous metastases in mucinous (MC) and nonmucinous (NMC) rectal cancer. METHODS: 111 patients with extraperitoneal locally advanced rectal cancer who underwent pelvic MRI, DWI and FDG PET-CT were stratified into MC (n=23) and NMC (n=88)...
November 15, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27822263/focal-sinusoidal-obstruction-syndrome-caused-by-oxaliplatin-induced-chemotherapy-a-case-report
#16
Takaharu Kawai, Shintaro Yamazaki, Atsuko Iwama, Tokio Higaki, Masahiko Sugitani, Tadatoshi Takayama
INTRODUCTION: Sinusoidal obstruction syndrome (SOS) is a severe adverse event of long-term chemotherapy in patients with colorectal cancer. It usually develops as liver congestion due to diffuse microscopic obstruction in liver parenchyma. In contrast, it sometimes appears as a liver mass occurring with local parenchymal hemorrhaging, and is often misdiagnosed as liver metastasis. CASE PRESENTATION: A 40-year-old woman with rectal cancer underwent high anterior resection and partial liver resection of segment 7 due to synchronous liver metastasis...
September 2016: Hepatitis Monthly
https://www.readbyqxmd.com/read/27819749/does-mri-help-in-the-pre-operative-evaluation-of-pelvic-fracture-urethral-distraction-defect-a-pilot-study
#17
Rajadoss Muthukrishna Pandian, Nirmal Thampi John, Anu Eapen, B Antonisamy, Antony Devasia, Nitin Kekre
OBJECTIVES: To study the usefulness of MRI in preoperative evaluation of PFUDD. Can MRI provide additional information on urethral distraction defect (UDD) and cause of erectile dysfunction (ED)? MATERIALS AND METHODS: In this prospective study, consecutive male patients presenting with PFUDD were included from Feb 2011 till Dec 2012. Those with traumatic spinal cord injury and pre-existing ED were excluded. Patients were assessed using IIEF questionnaire, retrograde urethrogram and micturating cystourethrogram (RGU+MCU) and MRI pelvis...
November 2, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27819636/the-importance-of-preoperative-stadialization-of-rectal-cancer-using-multiparametric-mri-a-systematic-review
#18
Ferdinand Bauer
A correct preoperative stadialization of rectal carcinoma has a direct influence upon its therapeutic strategy, resulting in a significant improvement of the survival rate and life quality after the treatment. The therapeutic strategy refers to the option of undergoing or not preoperative radiochemotherapy before the total mesorectal excision (TME). The technical advances in the magnetic resonance domain makes possible the multiparametric examinations (mp MRI) with medical equipments (3T models are common) good enough to obtain images having an excellent quality, which allow a correct diagnosis of the local tumour spread...
2016: Chirurgia
https://www.readbyqxmd.com/read/27816539/feasibility-study-of-toxicity-outcomes-using-gec-estro-contouring-guidelines-on-ct-based-instead-of-mri-based-planning-in-locally-advanced-cervical-cancer-patients
#19
Vicky Koh, Bok Ai Choo, Khai Mun Lee, Teng Hwee Tan, Jen Hui Jeffrey Low, Soon Yau Joseph Ng, Arunachalam Ilancheran, Liang Shen, Johann Tang
PURPOSE: To report late rectal and bladder toxicity outcomes of a CT-based image-guided brachytherapy (IGBT) technique for treatment of cervical cancer. METHODS AND MATERIALS: Between 2008 and 2014, 95 women with International Federation of Gynecology and Obstetrics stage IB to IVA cervical carcinoma treated with definitive concurrent cisplatin-based chemotherapy and external beam radiation therapy 50.4 Gy in 28 fractions followed by planned prescription dose of 7 Gy × 4 fractions of high-dose-rate IGBT was retrospectively reviewed...
November 2, 2016: Brachytherapy
https://www.readbyqxmd.com/read/27806062/an-mri-compatible-high-frequency-ac-resistive-heating-system-for-homeothermic-maintenance-in-small-animals
#20
Stuart Gilchrist, Ana L Gomes, Paul Kinchesh, Veerle Kersemans, Philip D Allen, Sean C Smart
PURPOSE: To develop an MRI-compatible resistive heater, using high frequency alternating current (AC), for temperature maintenance of anaesthetised animals. MATERIALS AND METHODS: An MRI-compatible resistive electrical heater was formed from narrow gauge wire connected to a high frequency (10-100 kHz) AC power source. Multiple gradient echo images covering a range of echo times, and pulse-acquire spectra were acquired with the wire heater powered using high frequency AC or DC power sources and without any current flowing in order to assess the sensitivity of the MRI acquisitions to the presence of current flow through the heater wire...
2016: PloS One
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