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Reza Shahryar-Kamrani, Hossein Saremi, Leila Oryadi-Zanjani, Mohammad Hossein Nabian, Azita Amoozadeh, Amir Hossein Moradi
BACKGROUND: Evolving wrist arthroscopy requires creating new portals, and creating portals reciprocally leads to increased indications for arthroscopic wrist procedures. To facilitate access to the lunate bone and fossa for new arthroscopic procedures, a new portal was used. This is a cadaveric study of this portal. OBJECTIVES: In this cadaveric study, we evaluated a portal in wrist arthroscopy for procedures involving the lunate bone and lunate fossa. MATERIALS AND METHODS: Seventeen wrists from 10 fresh cadavers were included in this study...
July 2016: Iranian Red Crescent Medical Journal
Mohsen Rashidi, Seyed Ali Ziai, Taraneh Moini Zanjani, Ahad Khalilnezhad, Hamidreza Jamshidi, Davar Amani
BACKGROUND: Resistance to chemotherapy is a growing concern, thus natural anticancer agents are drawing the attention of many scientists and clinicians. One natural anticancer agent, umbelliprenin, is a coumarin produced by many species of Ferula. OBJECTIVES: We aimed to examine the inhibitory effect of umbelliprenin on human and mouse bone marrow-derived stem cells (BMDSCs), peripheral blood mononuclear cells (PBMCs), and different cancer cell lines. MATERIALS AND METHODS: In this in vitro experimental study, the HT29, CT26, MCF-7, 4T1, A172, and GL26 cancer cells and human and mouse BMDSCs and PBMCs were cultured in RPMI-1640 medium supplemented with 10% fetal bovine serum (FBS), incubated at 37°C for 24 hours in a 5% CO2 atmosphere, and then were treated with different concentrations of umbelliprenin dissolved in dimethyl sulfoxide (DMSO) (3, 6, 12, 25, 50, 100, and 200 µg/mL) for 24, 48, and 72 hours at 37°C...
July 2016: Iranian Red Crescent Medical Journal
Arezoo Rasti, Maryam Abolhasani, Leili Saeednejad Zanjani, Mojgan Asgari, Mitra Mehrazma, Zahra Madjd
PURPOSE: Cancer stem cells (CSCs) represent a population with tumour-initiating, self-renewal, and differentiation potential. This study aimed to evaluate the expression patterns and clinical significance of chemokine receptor type 4 (CXCR4) as a novel CSC marker in renal cell carcinoma (RCC). METHODS: The expression of CXCR4 was examined in 173 well-defined renal tumour tissues, including 106 (61.5 %) clear cell renal cell carcinomas (ccRCCs), 35 (20 %) papillary renal cell carcinomas (pRCCs), and 32 (18...
September 16, 2016: Journal of Cancer Research and Clinical Oncology
Faika Zanjani, Lauren Crook, Rachel Smith, Demetra Antimisiaris, Nancy Schoenberg, Catherine Martin, Richard Clayton
OBJECTIVES: To examine rural and urban pharmacy staff perceptions on messaging, barriers, and motivators for preventing alcohol and medication interactions (AMI) in older adults (≥65 years of age). METHODS: A survey was distributed through the local pharmacist association and statewide pharmacy registry in Kentucky. A total of 255 responses were received from pharmacists, pharmacy technicians, and pharmacy students. RESULTS: Across rural and urban regions alike, among the AMI prevention messages provided, participants identified the most important messages to be: AMI can be potentially dangerous and life threatening; emergency rooms should be used when experiencing an AMI; and doctors and pharmacists should be consulted about AMI...
September 2016: Journal of the American Pharmacists Association: JAPhA
Jierong Cheng, Samad Jafar-Zanjani, Hossein Mosallaei
A leaky-wave antenna is proposed that furnishes two-dimensional (2-D) beam scanning in both elevation and azimuth planes via electrical control in real time, and at a single frequency. The structure consists of a graphene sheet on a metal-backed substrate. The 2-D beam-scanning performance is achieved through the proper biasing configuration of graphene. Traditional pixel-by-pixel electrical control makes the biasing network a huge challenge for chip-scale designs in the terahertz regime and beyond. The method presented here enables dynamic control by applying two groups of one-dimensional biasing on the sides of the sheet...
August 1, 2016: Applied Optics
Tracy Davis, Pamela B Teaster, John F Watkins, Alice C Thornton, Linda Alexander, Faika Zanjani
The purpose of this research was to explore primary care providers' willingness and ability to increase HIV prevention efforts among older adults and to gain recommendations for improving HIV prevention in primary care settings. Data were collected through 24 semistructured interviews with primary care providers. The results of the study reveal that the majority of providers find it necessary to increase HIV prevention efforts in primary care settings and are willing to do so; however, they cannot do so without assistance...
July 6, 2016: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
Elham Valikhanfard-Zanjani, Abbas Zare-Mirakabadi, Shahrbanoo Oryan, Hamid Reza Goodarzi, Mahdise Rajabi
BACKGROUND: Latrodectism, a syndrome caused by Latrodectus genus, is one of the clinical problems that occur predominantly in north east of Iran. Nowadays antivenom therapy has become the most useful treatment for animal bites; however there is still a controversy about route and time of antivenom administration in spider bite. The aim of the present study was to determine the efficacy of specific antivenom in neutralizing hepatic and renal symptoms 24 h after Latrodectus dahli envenomation...
June 2016: Journal of Arthropod-borne Diseases
Arash Beiraghi-Toosi, Ezatollah Rezaei, Elham Zanjani
BACKGROUND: Hyperactivity of depressor septi nasi muscle leads to smiling deformity and nasal tip depression. Lateral fascicles of this muscle help in widening the nostrils. The purpose of this study was to evaluate the relationship between the nasal length changes and the alar base and the alar flaring changes during smile. METHODS: Standard photographs are performed in the face and lateral views with forward gaze in the repose and maximum smile. Nasal length, alar base, and alar flaring were measured on the prints of the photographs...
January 2016: World Journal of Plastic Surgery
Saloomeh Mokhtari, Evan J Colletti, Anthony Atala, Esmail D Zanjani, Christopher D Porada, Graça Almeida-Porada
In utero hematopoietic stem/progenitor cell transplantation (IUHSCT) has only been fully successful in the treatment of congenital immunodeficiency diseases. Using sheep as a large animal model of IUHSCT, we demonstrate that administration of CD146(+)CXCL12(+)VEGFR2(+) or CD146(+)CXCL12(+)VEGFR2(-) cells prior to, or in combination with, hematopoietic stem/progenitor cells (HSC), results in robust CXCL12 production within the fetal marrow environment, and significantly increases the levels of hematopoietic engraftment...
June 14, 2016: Stem Cell Reports
Taraneh Moini-Zanjani, Seyed-Nasser Ostad, Farzaneh Labibi, Haleh Ameli, Nariman Mosaffa, Masoumeh Sabetkasaei
BACKGROUND: Evidence indicates that neuropathic pain pathogenesis is not confined to changes in the activity of neuronal systems but involves interactions between neurons, inflammatory immune and immune-like glial cells. Substances released from immune cells during inflammation play an important role in development and maintenance of neuropathic pain. It has been found that minocycline suppresses the development of neuropathic pain. Here, we evaluated the analgesic effect of minocycline in a chronic constriction injury (CCI) model of neuropathic pain in rat and assessed IL-6 concentration from cultured macrophage and microglia cells...
November 2016: Iranian Biomedical Journal
Faika Zanjani, Rachel Smith, Svetla Slavova, Richard Charnigo, Nancy Schoenberg, Catherine Martin, Richard Clayton
BACKGROUND: Alcohol and medication interactions are projected to increase due to the growth of older adults that are unsafely consuming alcohol and medications. Plus, aging adults who reside in rural areas are at the highest risk of experiencing medication interactions. OBJECTIVE: Estimate concurrent alcohol and medication (alcohol/medication) hospitalizations in adults 50+ years, comparing age groups and rural/urban regions. METHODS: Kentucky nonfederal, acute care inpatient hospital discharge electronic records for individuals aged 50+ years from 2001 to 2012 were examined...
July 2016: American Journal of Drug and Alcohol Abuse
Ali Saber, Seyed Mahmoud Tabatabaei, Goodarz Akasheh, Mojtaba Sehat, Zahra Zanjani, Bagher Larijani
BACKGROUND: According to general ethical and legal principles, valid consent must be obtained before starting any procedure. OBJECTIVES: Due to the lack of a standard tool for assessing patients' capacity to consent to medical treatment in Iran, the present study was carried out aiming to devise a Persian version of a cross-cultural adaptation of the MacArthur competence assessment tool. PATIENTS AND METHODS: By reviewing different methods of cultural translation and adaptation for assessment tools, and due to the lack of consensus on its processes, we selected Wild's model as one of the most comprehensive methods in this regard...
March 2016: Archives of Trauma Research
Samad Jafar-Zanjani, Jierong Cheng, Hossein Mosallaei
An efficient auxiliary differential equation method for incorporating 2D inhomogeneous dispersive impedance sheets in the finite-difference time-domain solver is presented. This unique proposed method can successfully solve optical problems of current interest involving 2D sheets. It eliminates the need for ultrafine meshing in the thickness direction, resulting in a significant reduction of computation time and memory requirements. We apply the method to characterize a novel broad-beam leaky-wave antenna created by cascading three sinusoidally modulated reactance surfaces and also to study the effect of curvature on the radiation characteristic of a conformal impedance sheet holographic antenna...
April 10, 2016: Applied Optics
D S Zanjani, M Afzal Aghaee, Z Badiei, R Mehrasa, A Roodsarabi, M E Khayyami, M Shahabi
BACKGROUND AND OBJECTIVES: Bombay phenotype is characterized by the lack of H substance both on red blood cell (RBC) surface and in body secretions. Mutations of fucosyltransferase 1 (FUT1) and fucosyltransferase 2 (FUT2) genes are resulted in this rare phenotype. MATERIALS AND METHODS: Five unrelated patients were tested by hemagglutination and adsorption/elution techniques for the presence of ABH antigens. The saliva specimens were analysed by hemagglutination inhibition method...
July 2016: Vox Sanguinis
Sahand Zanjani-Pour, C Peter Winlove, Christopher W Smith, Judith R Meakin
Finite element (FE) modelling is an established technique for investigating spinal biomechanics. Using image data to produce FE models with subject-specific geometry and displacement boundary conditions may help extend their use to the assessment spinal loading in individuals. Lumbar spine magnetic resonance images from nine participants in the supine, standing and sitting postures were obtained and 2D poroelastic FE models of the lumbar spine were created from the supine data. The rigid body translation and rotation of the vertebral bodies as the participant moved to standing or sitting were applied to the model...
April 11, 2016: Journal of Biomechanics
Hamidreza Mohammadi, Mohammad Shokrzadeh, Zahra Aliabadi, Bamdad Riahi-Zanjani
The frequency and levels of aflatoxin M1 (AFM1) in pasteurized milk samples in Sari, located in Mazandaran province, Iran, were determined by enzyme immunoassay. Seventy-six samples of pasteurized milk from different retail stores were randomly collected over four seasons during the year 2015. AFM1 contamination was detected in all milk samples. The mean concentration of aflatoxin M1 was 65.8 ng/l, with a range of 11.7-106.6 ng/l. The highest AFM1 level was detected in milk samples collected during spring. Forty-six (60...
May 2016: Mycotoxin Research
Leila Oriady Zanjani, Masoumeh Firouzi, Mohammad Hossein Nabian, Shayan Abdollah Zadegan, Mohsen Nategh, Reza Erfanian, Ahmad Mohebbi Ashtiani, Reza Shahryar Kamrani
Background Extraneural scar formation is a challenging problem in nerve repair. Rodent models of scar induction, with their high regenerative capacity, suffer from lack of comparable similarities with human cases. In this study, we attempted to find a reliable and reproducible method of extraneural scarring with a significant impact on the peripheral nerve function. Methods A total of 60 rats were divided into three scar induction groups: abrasion (with a small piece of compressed steel wool), mincing (with extracorporeal mincing of adductor muscle and a 5-mm wide strip of the anterior border of the biceps femoris), and electrocoagulation (with a bipolar coagulator)...
May 2016: Journal of Reconstructive Microsurgery
Negar Talaei Zanjani, Monica Miranda-Saksena, Peter Valtchev, Russell J Diefenbach, Linda Hueston, Eve Diefenbach, Fareed Sairi, Vincent G Gomes, Anthony L Cunningham, Fariba Dehghani
A marine-derived compound, abalone hemocyanin, from Haliotis rubra was shown to have a unique mechanism of antiviral activity against herpes simplex virus 1 (HSV-1) infections. In vitro assays demonstrated the dose-dependent and inhibitory effect of purified hemocyanin against HSV-1 infection in Vero cells with a 50% effective dose (ED50) of 40 to 50 nM and no significant toxicity. In addition, hemocyanin specifically inhibited viral attachment and entry by binding selectively to the viral surface glycoproteins gD, gB, and gC, probably by mimicking their receptors...
February 2016: Antimicrobial Agents and Chemotherapy
Iran Malekzadeh, Vahid Ziaee, Taravat Sadrosadat, Mohammad-Hassan Moardinejad, Keyhan Sayadpour-Zanjani
INTRODUCTION: Early diagnosis and treatment of Kawasaki disease as the most common cause of acquired heart disease in childhood, may significantly improve the prognosis. Diagnosing infantile Kawasaki (younger than a year) is difficult because of obscure symptoms; at the same time they are at the higher risk of coronary abnormalities. CASE PRESENTATION: We report three infants with prolonged (more than 5 days) fever and peripheral gangrene without any other clinical manifestations of Kawasaki disease...
December 2015: Iranian Journal of Pediatrics
G Mahmudi, M Nikpour, M Azadbackt, R Zanjani, M A Jahani, A Aghamohammadi, Y Jannati
OBJECTIVE: The aim of this study was to assess the impact of turmeric cream on the healing of Caesarean wound. METHODS: This study was done as a randomized double blind trial in three groups on women who had a Caesarean operation. The redness, oedema, ecchymosis, drainage, approximation (REEDA) scale was used to evaluate the wound healing process. The χ², analysis of variance (ANOVA) and Tukey tests were used for statistical analysis. RESULTS: Seven days after the surgery, the averages of REEDA score in the intervention, placebo and control groups were respectively, 0...
September 2015: West Indian Medical Journal
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