keyword
MENU ▼
Read by QxMD icon Read
search

exer

keyword
https://www.readbyqxmd.com/read/29449504/response-to-tumor-necrosis-factor-inhibition-in-male-and-female-patients-with-ankylosing-spondylitis-data-from-a-swiss-cohort
#1
Monika Hebeisen, Regula Neuenschwander, Almut Scherer, Pascale Exer, Ulrich Weber, Giorgio Tamborrini, Raphael Micheroli, Lukas M Wildi, Pascal Zufferey, Michael J Nissen, Peter M Villiger, Jürg Bernhard, Axel Finckh, Irene E van der Horst-Bruinsma, Joachim Sieper, Robert Landewé, Désirée van der Heijde, Adrian Ciurea
OBJECTIVE: To investigate sex differences in connection with the effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with ankylosing spondylitis (AS). METHODS: A total of 440 patients with AS (294 men; 146 women) initiating a first TNFi in the prospective Swiss Clinical Quality Management Cohort were included. We evaluated the proportion of patients achieving the 20% and 40% improvement in the Assessment of Spondyloarthritis international Society criteria (ASAS20 and ASAS40) as well as Ankylosing Spondylitis Disease Activity Score (ASDAS) improvement and status scores at 1 year...
February 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29387634/effects-of-endurance-exercise-and-doxorubicin-on-skeletal-muscle-myogenic-regulatory-factor-expression
#2
Colin J Quinn, David S Hydock
Background: The skeletal muscle toxicity that accompanies the chemotherapy drug doxorubicin (DOX) may lead to cancer patient weakness and fatigue. This myotoxicity involves myogenic regulatory factor (MRF) disruption which alters muscle integrity and regeneration. Endurance exercise enhances MRF expression and thereby may mitigate DOX-induced MRF disruptions. This study examined the effects of endurance training and DOX treatment on myogenic regulatory factor (MRF) expression. Methods: Male rats were exercise trained (EXER) or remained sedentary (SED) for two weeks...
July 2017: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/29224176/validation-of-a-method-for-estimating-energy-expenditure-during-walking-in-middle-aged-adults
#3
Nathan Caron, Teddy Caderby, Nicolas Peyrot, Chantal Verkindt, Georges Dalleau
PURPOSE: The aim of this study was to test the validity of a method using an inertial measurement unit for estimating activity-related energy expenditure (AEE) during walking in middle-aged adults. METHODS: Twenty healthy middle-aged participants completed different treadmill walking trials with an inertial measurement unit adhered to their lower back. Gas exchange was monitored with indirect calorimetry. Mechanical data were used to estimate AEE from an algorithm developed by Bouten et al...
December 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28939631/tnf-blockers-inhibit-spinal-radiographic-progression-in-ankylosing-spondylitis-by-reducing-disease-activity-results-from-the-swiss-clinical-quality-management-cohort
#4
Christoph Molnar, Almut Scherer, Xenofon Baraliakos, Manouk de Hooge, Raphael Micheroli, Pascale Exer, Rudolf O Kissling, Giorgio Tamborrini, Lukas M Wildi, Michael J Nissen, Pascal Zufferey, Jürg Bernhard, Ulrich Weber, Robert B M Landewé, Désirée van der Heijde, Adrian Ciurea
OBJECTIVES: To analyse the impact of tumour necrosis factor inhibitors (TNFis) on spinal radiographic progression in ankylosing spondylitis (AS). METHODS: Patients with AS in the Swiss Clinical Quality Management cohort with up to 10 years of follow-up and radiographic assessments every 2 years were included. Radiographs were scored by two readers according to the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) with known chronology. The relationship between TNFi use before a 2-year radiographic interval and progression within the interval was investigated using binomial generalised estimating equation models with adjustment for potential confounding and multiple imputation of missing values...
January 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28724442/impact-of-obesity-on-the-response-to-tumor-necrosis-factor-inhibitors-in-axial-spondyloarthritis
#5
Raphael Micheroli, Monika Hebeisen, Lukas M Wildi, Pascale Exer, Giorgio Tamborrini, Jürg Bernhard, Burkhard Möller, Pascal Zufferey, Michael J Nissen, Almut Scherer, Adrian Ciurea
BACKGROUND: Few studies have investigated the impact of obesity on the response to tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (axSpA). The aim of our study was to investigate the impact of different body mass index (BMI) categories on TNFi response in a large cohort of patients with axSpA. METHODS: Patients with axSpA within the Swiss Clinical Quality Management (SCQM) program were included in the current study if they fulfilled the Assessment in Spondyloarthritis International Society (ASAS) criteria for axSpA, started a first TNFi after recruitment, and had available BMI data as well as a baseline and follow-up visit at 1 year (±6 months)...
July 19, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28453295/postinjury-exercise-and-platelet-rich-plasma-therapies-improve-skeletal-muscle-healing-in-rats-but-are-not-synergistic-when-combined
#6
Paola Contreras-Muñoz, Joan Ramon Torrella, Xavier Serres, David Rizo-Roca, Meritxell De la Varga, Ginés Viscor, Vicente Martínez-Ibáñez, José Luis Peiró, Tero A H Järvinen, Gil Rodas, Mario Marotta
BACKGROUND: Skeletal muscle injuries are the most common sports-related injury and a major concern in sports medicine. The effect of platelet-rich plasma (PRP) injections on muscle healing is still poorly understood, and current data are inconclusive. PURPOSE: To evaluate the effects of an ultrasound-guided intramuscular PRP injection, administered 24 hours after injury, and/or posttraumatic daily exercise training for 2 weeks on skeletal muscle healing in a recently established rat model of skeletal muscle injury that highly mimics the muscle trauma seen in human athletes...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28275666/data-representing-two-separate-lc-ms-methods-for-detection-and-quantification-of-water-soluble-and-fat-soluble-vitamins-in-tears-and-blood-serum
#7
Maryam Khaksari, Lynn R Mazzoleni, Chunhai Ruan, Robert T Kennedy, Adrienne R Minerick
Two separate liquid chromatography (LC)-mass spectrometry (MS) methods were developed for determination and quantification of water-soluble and fat-soluble vitamins in human tear and blood serum samples. The water-soluble vitamin method was originally developed to detect vitamins B1, B2, B3 (nicotinamide), B5, B6 (pyridoxine), B7, B9 and B12 while the fat-soluble vitamin method detected vitamins A, D3, 25(OH)D3, E and K1. These methods were then validated with tear and blood serum samples. In this data in brief article, we provide details on the two LC-MS methods development, methods sensitivity, as well as precision and accuracy for determination of vitamins in human tears and blood serum...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/27620342/what-is-the-best-treatment-before-bariatric-surgery-exercise-exercise-and-group-therapy-or-conventional-waiting-a-randomized-controlled-trial
#8
Emilian Rejane Marcon, S Baglioni, L Bittencourt, C L N Lopes, C R Neumann, M R M Trindade
OBJECTIVE: This trial's objective was to investigate the effect of an exercise program with and without cognitive-behavioral therapy (CBT), compared by a control group, on weight, functional capacity, and cardiometabolic profile of morbidly obese individuals while waiting for bariatric surgery. MATERIALS AND METHODS: This randomized controlled trial investigated the effect of a 4-month low-intensity exercise program (two weekly sessions of 25 min each) on 66 morbidly obese individuals awaiting bariatric surgery...
March 2017: Obesity Surgery
https://www.readbyqxmd.com/read/27600736/pragmatic-assessment-of-exercise-in-routine-care-using-an-mdhaq-associations-with-changes-in-rapid3-and-other-clinical-variables
#9
Isabel Castrejón, Yusuf Yazici, Selda Celik, Theodore Pincus
BACKGROUND: Exercise is associated with major benefits in patients with rheumatic diseases for both cardiovascular and rheumatic status. However, information about exercise generally is not collected systematically in routine rheumatology care. A multidimensional health assessment questionnaire (MDHAQ), which was designed for busy clinical settings, includes a query about exercise status. We analyzed possible associations between change in MDHAQ exercise scores and other MDHAQ measures in patients with various rheumatic diseases over one year...
September 6, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27219616/targeting-the-sympatho-adrenergic-link-in-chronic-rheumatic-mitral-regurgitation-assessing-the-role-of-oral-beta-blockers
#10
RANDOMIZED CONTROLLED TRIAL
Dhabaleswar Sahoo, Aditya Kapoor, Archana Sinha, Roopali Khanna, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Pravin Goel
INTRODUCTION: Chronic mitral regurgitation (MR) is characterized by adverse ventricular remodeling and progressive LV dysfunction leading to heart failure (HF). Beta-blockers (BB) improve LV remodeling and prognosis in patients with HF. As chronic severe MR results in neuroendocrine activation similar to HF, it is likely that BB may also exert favorable effects in these patients. No study has assessed the role of oral BB therapy in chronic rheumatic MR. AIMS: A total of 100 patients of chronic rheumatic MR (mean age 30±13...
August 2016: Cardiovascular Therapeutics
https://www.readbyqxmd.com/read/27015429/the-effect-of-comedication-with-a-conventional-synthetic-disease-modifying-antirheumatic-drug-on-drug-retention-and-clinical-effectiveness-of-anti-tumor-necrosis-factor-therapy-in-patients-with-axial-spondyloarthritis
#11
Michael J Nissen, Adrian Ciurea, Jürg Bernhard, Giorgio Tamborrini, Ruediger Mueller, Bettina Weiss, Martin Toniolo, Pascale Exer, Cem Gabay, Axel Finckh
OBJECTIVE: To explore the effect of comedication with conventional synthetic disease-modifying antirheumatic drugs (DMARDs) on drug retention and clinical effectiveness of tumor necrosis factor inhibitors (TNFi) in patients with axial spondyloarthritis (SpA). METHODS: The study included all patients starting treatment with a TNFi in a large prospective cohort of axial SpA patients (Swiss Clinical Quality Management in axial SpA). Crude drug retention was analyzed using the Kaplan-Meier method, and in adjusted analyses, Cox proportional hazards regression was used to model TNFi discontinuation...
September 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/26988766/whole-body-fat-oxidation-increases-more-by-prior-exercise-than-overnight-fasting-in-elite-endurance-athletes
#12
RANDOMIZED CONTROLLED TRIAL
Ulrika Andersson Hall, Fredrik Edin, Anders Pedersen, Klavs Madsen
The purpose of this study was to compare whole-body fat oxidation kinetics after prior exercise with overnight fasting in elite endurance athletes. Thirteen highly trained athletes (9 men and 4 women; maximal oxygen uptake: 66 ± 1 mL·min(-1)·kg(-1)) performed 3 identical submaximal incremental tests on a cycle ergometer using a cross-over design. A control test (CON) was performed 3 h after a standardized breakfast, a fasting test (FAST) 12 h after a standardized evening meal, and a postexercise test (EXER) after standardized breakfast, endurance exercise, and 2 h fasting recovery...
April 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/26886474/effects-of-virtual-reality-training-exergaming-compared-to-alternative-exercise-training-and-passive-control-on-standing-balance-and-functional-mobility-in-healthy-community-dwelling-seniors-a-meta-analytical-review
#13
REVIEW
Lars Donath, Roland Rössler, Oliver Faude
BACKGROUND: Balance training is considered an important means to decrease fall rates in seniors. Whether virtual reality training (VRT) might serve as an appropriate treatment strategy to improve neuromuscular fall risk parameters in comparison to alternative balance training programs (AT) is as yet unclear. OBJECTIVE: To examine and classify the effects of VRT on fall-risk relevant balance performance and functional mobility compared to AT and an inactive control condition (CON) in healthy seniors...
September 2016: Sports Medicine
https://www.readbyqxmd.com/read/26181683/the-yin-and-yang-of-formative-research-in-designing-serious-exer-games
#14
Ann DeSmet, António Palmeira, Alicia Beltran, Leah Brand, Vanessa Fernandes Davies, Debbe Thompson
Despite its relevance, formative research on games may be an undervalued part of the game development process. At the 2014 International Society of Behavioral Nutrition and Physical Activity exergaming preconference satellite meeting, a roundtable discussion was held to assemble experiences and suggestions on enhancing the use of formative research in the development of active videogames (i.e., exergames). This article presents a summary of the concepts discussed. The discussants concluded that, although formative research may slightly expand the project timeline, the potential benefits include a game more in line with preferences of the intended users, with better operationalized theoretical constructs and broader stakeholder support, facilitating implementation and sustainability...
February 2015: Games for Health
https://www.readbyqxmd.com/read/26112934/synergic-carcinostatic-effects-of-ascorbic-acid-and-hyperthermia-on-ehrlich-ascites-tumor-cell
#15
Y Saitoh, T Yoshimoto, S Kato, N Miwa
AIM: In this study, we evaluated the carcinostatic effects of combined ascorbic acid (AsA) and a capacitive-resistive electric transfer (CRet) hyperthermic apparatus-induced hyperthermic treatment on Ehrlich ascites tumor (EAT) cells. MATERIALS AND METHODS: EAT cells were exposed to various AsA (0-10 mM) concentrations for 1 h; they subsequently underwent CRet treatment for 15 min at 42 °C. Cell viability was assessed by the WST-8 assay 24 h after the combined treatment...
June 2015: Experimental Oncology
https://www.readbyqxmd.com/read/25845088/exercise-training-reduces-high-mobility-group-box-1-protein-levels-in-women-with-breast-cancer-findings-from-the-diana-5-study
#16
RANDOMIZED CONTROLLED TRIAL
Francesco Giallauria, Marco Gentile, Paolo Chiodini, Franco Berrino, Amalia Mattiello, Luigi Maresca, Alessandra Vitelli, Maria Mancini, Alessandra Grieco, Rosa Lucci, Giorgio Torella, Salvatore Panico, Carlo Vigorito
PURPOSE: To determine whether exercise training might exert anti-inflammatory effect by reducing HMGB1 levels in women with breast cancer (BC). METHODS: We analyzed monocentric data from the DIANA (DIET AND ANDROGENS)-5 PROJECT. Study population consisted of 94 patients randomized into two groups: 61 patients (53 +/- 8 yrs, training group) were assigned to a structured exercise training intervention (3 times/week for the first 3 months, and once /week for the following 9 months); whereas 33 patients (52 +/- 7 yrs, control group) followed only the general indications to adhere to the life-style intervention suggestions of the DIANA protocol...
June 2014: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/25824058/physiological-and-psychophysiological-responses-to-an-exer-game-training-protocol
#17
Shaw Bronner, Russell Pinsker, Rutika Naik, J Adam Noah
OBJECTIVES: Exer-games and virtual reality offer alternative opportunities to provide neuro-rehabilitation and exercise that are fun. Our goal was to determine how effective they are in achieving motor learning goals and fitness benefits as players gain experience. DESIGN: We employed a repeated measures design to determine changes in physical exertion and engagement with training. METHODS: Fourteen healthy adults trained on the XBOX Kinect video game Dance Central using a skill-based protocol to examine changes in energy expenditure (EE), heart rate (HR), METs, limb movement, game proficiency, and player engagement in initial, post-training, and transfer-testing of a full-body dance exer-game...
March 2016: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/25703183/wii-fit-exer-game-training-improves-sensory-weighting-and-dynamic-balance-in-healthy-young-adults
#18
Brian L Cone, Susan S Levy, Daniel J Goble
The Nintendo Wii Fit is a balance training tool that is growing in popularity due to its ease of access and cost-effectiveness. While considerable evidence now exists demonstrating the efficacy of the Wii Fit, no study to date has determined the specific mechanism underlying Wii Fit balance improvement. This paucity of knowledge was addressed in the present study using the NeuroCom Balance Manager's Sensory Organization Test (SOT) and Limits of Stability (LOS) test. These well-recognized posturography assessments, respectively, measure sensory weighting and dynamic stability mechanisms of balance...
February 2015: Gait & Posture
https://www.readbyqxmd.com/read/25667205/impaired-response-to-treatment-with-tumour-necrosis-factor-%C3%AE-inhibitors-in-smokers-with-axial-spondyloarthritis
#19
Adrian Ciurea, Almut Scherer, Ulrich Weber, Pascale Exer, Jürg Bernhard, Giorgio Tamborrini, Myriam Riek, Rüdiger B Müller, Bettina Weiss, Michael J Nissen, Rudolf Kissling, Beat A Michel, Axel Finckh
OBJECTIVES: To investigate the impact of smoking on the response to treatment with a first tumour necrosis factor inhibitor (TNFi) in patients with axial spondyloarthritis (axSpA) in a real-life cohort. METHODS: Patients fulfilling the Assessment of SpondyloArthritis international Society (ASAS) classification criteria for axSpA in the Swiss Clinical Quality Management Cohort were included in this study. The potential association between smoking status and differential response to TNFi in terms of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Ankylosing Spondylitis Disease Activity Score (ASDAS) was analysed using multiple adjusted longitudinal mixed effect models...
March 2016: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/25362654/treatment-with-tumor-necrosis-factor-inhibitors-in-axial-spondyloarthritis-comparison-between-private-rheumatology-practices-and-academic-centers-in-a-large-observational-cohort
#20
COMPARATIVE STUDY
Adrian Ciurea, Ulrich Weber, Daniel Stekhoven, Almut Scherer, Giorgio Tamborrini, Jürg Bernhard, Martin Toniolo, Peter M Villiger, Pascal Zufferey, Rudolf O Kissling, Beat A Michel, Pascale Exer
OBJECTIVE: To evaluate the initiation of and response to tumor necrosis factor (TNF) inhibitors for axial spondyloarthritis (axSpA) in private rheumatology practices versus academic centers. METHODS: We compared newly initiated TNF inhibition for axSpA in 363 patients enrolled in private practices with 100 patients recruited in 6 university hospitals within the Swiss Clinical Quality Management (SCQM) cohort. RESULTS: All patients had been treated with ≥ 1 nonsteroidal antiinflammatory drug and > 70% of patients had a baseline Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) ≥ 4 before anti-TNF agent initiation...
January 2015: Journal of Rheumatology
keyword
keyword
30088
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"