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https://www.readbyqxmd.com/read/29042058/exercise-induced-complete-atrioventricular-block-utility-of-exercise-stress-test
#1
Srikanth Yandrapalli, Prakash Harikrishnan, Amole Ojo, Venkat Lakshmi Kishan Vuddanda, Diwakar Jain
Exercise induced complete atrioventricular block (EIAVB) is a relatively uncommon condition. This phenomenon is clinically important because it can mimic symptoms of other cardiovascular conditions and may be associated with exercise intolerance and subsequent syncope. A 76year old man with long-standing hypertension and diabetes mellitus presented with recurrent episodes of lightheadedness and syncope with physical activity. ECG showed sinus rhythm with first degree atrioventricular block. Echocardiography did not show any valvular disease causing his symptoms...
September 10, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29041912/quality-of-life-questionnaire-predicts-poor-exercise-capacity-only-in-hfpef-and-not-in-hfref
#2
Artan Ahmeti, Michael Y Henein, Pranvera Ibrahimi, Shpend Elezi, Edmond Haliti, Afrim Poniku, Arlind Batalli, Gani Bajraktari
BACKGROUND: The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is the most widely used measure of quality of life (QoL) in HF patients. This prospective study aimed to assess the relationship between QoL and exercise capacity in HF patients. METHODS: The study subjects were 118 consecutive patients with chronic HF (62 ± 10 years, 57 females, in NYHA I-III). Patients answered a MLHFQ questionnaire in the same day of complete clinical, biochemical and echocardiographic assessment...
October 17, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29040545/ethnicity-and-place-the-geography-of-diabetes-inequalities-under-a-strong-welfare-state
#3
Elias Nosrati, Anne Karen Jenum, Anh Thi Tran, Sir Michael Marmot, Lawrence Peter King
Background: The Nordic 'health paradox' designates the seemingly puzzling empirical reality in which, despite the presence of strong welfare policies targeting structural inequalities, distinct health disparities persist in Scandinavian societies. In Norway, previous research has shown that inequalities in diabetes prevalence are particularly salient, notably between ethnic groups. These have often been attributed to lifestyle, socioeconomic factors, or genetics. No previous research has sought to investigate the sociospatial mediation of diabetes inequities...
October 10, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29038723/survey-of-awareness-of-diabetes-mellitus-among-the-arar-population-northern-border-region-of-saudi-arabia
#4
Aseel Menwer Alanazi, Nagah Mohamed Abo El-Fetoh, Hanan Khalid Alotaibi, Khalid Ayed Alanazi, Banan Khalid Alotaibi, Sultan Majed Alshammari, Saud Rteamy Alanazi, Meshari Dalaf Alhazmi, Yousef Talal Alshammari, Zaid Qati Alshammari
BACKGROUND: Diabetes Mellitus (DM) is one of the most widely prevalent diseases in Saudi Arabia. Health education is considered an essential component to improve knowledge and change behavior. People affected by diabetes often have inadequate knowledge about the nature of diabetes, its risk factors and associated complication. OBJECTIVES: The aim of this study was to assess the awareness of the Arar population with various aspects of diabetes mellitus. METHODS: A cross-sectional study was carried out in Arar city, the capital of the Northern Province of Kingdom of Saudi Arabia (KSA)...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29038694/dietary-habits-physical-activity-and-diabetes-perception-among-patients-with-type-2-diabetes-mellitus-in-tabuk-city-saudi-arabia
#5
Nadiyah Abdullah Al-Mountashiri, Amal Mohammad Al-Zhrani, Shereen Fawzy Hafez Ibrahim, Hyder Othman Mirghani
BACKGROUND: Medical nutritional therapy is an important aspect of diabetes care, there is an increasing awareness of breakfast skipping, late dinner and meal contents on diabetes control. AIM: To assess dietary habits, physical activity and diabetes perception among patients with type 2 diabetes. METHODS: This case-control study was conducted among patients with diabetes mellitus at the diabetes center in Tabuk City, Saudi Arabia during the period from March through June 2017...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29038314/physical-activity-reduces-risk-of-premature-mortality-in-patients-with-type-1-diabetes-with-and-without-kidney-disease
#6
Heidi Tikkanen-Dolenc, Johan Wadén, Carol Forsblom, Valma Harjutsalo, Lena M Thorn, Markku Saraheimo, Nina Elonen, Heikki O Tikkanen, Per-Henrik Groop
OBJECTIVE: The aims of the study were to assess how baseline leisure-time physical activity (LTPA) and its exercise components intensity, duration, and frequency are associated with all-cause and cardiovascular mortality in patients with type 1 diabetes 1) overall, 2) stratified by presence or absence of chronic kidney disease (CKD), and 3) stratified by sex. RESEARCH DESIGN AND METHODS: The study design was prospective and observational and included 2,639 patients with type 1 diabetes from the ongoing nationwide multicenter Finnish Diabetic Nephropathy (FinnDiane) Study...
October 16, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29038293/loss-of-hepatic-amp-activated-protein-kinase-impedes-the-rate-of-glycogenolysis-but-not-gluconeogenic-fluxes-in-exercising-mice
#7
Curtis C Hughey, Freyja D James, Deanna P Bracy, E Patrick Donahue, Jamey D Young, Benoit Viollet, Marc Foretz, David H Wasserman
Pathologies including diabetes and conditions such as exercise place an unusual demand on liver energy metabolism, and this demand induces a state of energy discharge. Hepatic AMP-activated protein kinase (AMPK) has been proposed to inhibit anabolic processes such as gluconeogenesis in response to cellular energy stress. However, both AMPK activation and glucose release from the liver are increased during exercise. Here, we sought to test the role of hepatic AMPK in the regulation of in vivo glucose producing and citric acid cycle-related fluxes during an acute bout of muscular work...
October 16, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29038285/metabolic-effects-of-diet-and-exercise-in-patients-with-moderate-to-severe-ckd-a-randomized-clinical-trial
#8
T Alp Ikizler, Cassianne Robinson-Cohen, Charles Ellis, Samuel A E Headley, Katherine Tuttle, Richard J Wood, Elizabeth Elspeth Evans, Charles M Milch, Kelsey Anne Moody, Michael Germain, Chutatip Limkunakul, Aihua Bian, Thomas G Stewart, Jonathan Himmelfarb
CKD is steadily increasing along with obesity worldwide. Furthermore, obesity is a proinflammatory risk factor for progression of CKD and cardiovascular disease. We tested the hypothesis that implementation of caloric restriction and aerobic exercise is feasible and can improve the proinflammatory metabolic milieu in patients with moderate to severe CKD through a pilot, randomized, 2×2 factorial design trial. Of 122 participants consented, 111 were randomized to receive caloric restriction and aerobic exercise, caloric restriction alone, aerobic exercise alone, or usual care...
October 16, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29037162/feasibility-of-a-multi-modal-exercise-program-on-cognition-in-older-adults-with-type-2-diabetes-a-pilot-randomised-controlled-trial
#9
M L Callisaya, R M Daly, J E Sharman, D Bruce, T M E Davis, T Greenaway, M Nolan, R Beare, M G Schultz, T Phan, L C Blizzard, V K Srikanth
BACKGROUND: Type 2 Diabetes (T2D) is associated with increased risk of dementia. We aimed to determine the feasibility of a randomised controlled trial (RCT) examining the efficacy of exercise on cognition and brain structure in people with T2D. METHODS: A 6-month pilot parallel RCT of a progressive aerobic- and resistance-training program versus a gentle movement control group in people with T2D aged 50-75 years (n = 50) at the University of Tasmania, Australia...
October 16, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/29036909/diabetes-induced-dysfunction-of-mitochondria-and-stem-cells-in-skeletal-muscle-and-the-nervous-system
#10
REVIEW
Shin Fujimaki, Tomoko Kuwabara
Diabetes mellitus is one of the most common metabolic diseases spread all over the world, which results in hyperglycemia caused by the breakdown of insulin secretion or insulin action or both. Diabetes has been reported to disrupt the functions and dynamics of mitochondria, which play a fundamental role in regulating metabolic pathways and are crucial to maintain appropriate energy balance. Similar to mitochondria, the functions and the abilities of stem cells are attenuated under diabetic condition in several tissues...
October 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29036766/resistance-training-increases-fibroblast-growth-factor-21-and-irisin-levels-in-the-skeletal-muscle-of-zucker-diabetic-fatty-rats
#11
Hee-Jae Kim, Wook Song
PURPOSE: Although the fibroblast growth factor-21 (FGF-21) and irisin roles are well demonstrated in metabolic disease, there have been no reports investigating the effect of resistance exercise on FGF-21 and irisin levels in diabetic skeletal muscles. Therefore, this study aimed to investigate the change of FGF-21 and irisin levels in various skeletal muscles, and their association with muscle strength, following 8 weeks of resistance training using Zucker diabetic fatty rats (type 2 diabetic animal models)...
September 30, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29036763/effect-of-treadmill-exercise-on-skeletal-muscle-autophagy-in-rats-with-obesity-induced-by-a-high-fat-diet
#12
Do Keun Cho, Dong Hun Choi, Joon Yong Cho
PURPOSE: This study aimed to investigate the effects of treadmill exercise on body weight, blood biochemistry, and autophagy. METHODS: Triglyceride, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, insulin, and glucose levels were measured, the Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) score was calculated, and the soleus muscle was analyzed for autophagy-related factors (Beclin-1, p62, LC3, Lamp-2) in rats with obesity induced by a high-fat diet...
September 30, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29036762/low-intensity-aerobic-exercise-training-inhibition-of-skeletal-muscle-atrophy-in-high-fat-diet-induced-ovariectomized-rats
#13
Hye Jin Kim, Won Jun Lee
PURPOSE: Postmenopausal women are highly susceptible to diseases, such as obesity, type 2 diabetes, osteoporosis, or skeletal muscle atrophy and many people recognize the need for regular physical activity. Aerobic exercise training is known to improve the oxidative capacity and insulin sensitivity of skeletal muscles. This study aimed to investigate the role of low-intensity aerobic exercise training on skeletal muscle protein degradation or synthesis in the plantaris muscles of high-fat-fed ovariectomized rats...
September 30, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/29032504/resistance-exercise-improves-cardiac-function-and-mitochondrial-efficiency-in-diabetic-rat-hearts
#14
Tae Hee Ko, Jubert C Marquez, Hyoung Kyu Kim, Seung Hun Jeong, SungRyul Lee, Jae Boum Youm, In Sung Song, Dae Yun Seo, Hye Jin Kim, Du Nam Won, Kyoung Im Cho, Mun Gi Choi, Byoung Doo Rhee, Kyung Soo Ko, Nari Kim, Jong Chul Won, Jin Han
Metabolic disturbance and mitochondrial dysfunction are a hallmark of diabetic cardiomyopathy (DC). Resistance exercise (RE) not only enhances the condition of healthy individuals but could also improve the status of those with disease. However, the beneficial effects of RE in the prevention of DC and mitochondrial dysfunction are uncertain. Therefore, this study investigated whether RE attenuates DC by improving mitochondrial function using an in vivo rat model of diabetes. Fourteen Otsuka Long-Evans Tokushima Fatty rats were assigned to sedentary control (SC, n = 7) and RE (n = 7) groups at 28 weeks of age...
October 14, 2017: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/29031342/the-competitive-senior-athlete
#15
REVIEW
David A Soto-Quijano
Clinicians should discuss common health issues of the older population and how medical problems affect their sports performance. Patients with chronic conditions, such as hypertension and diabetes mellitus, benefit from participation in sports. However, special care should be taken to keep the patient healthy and minimize effects of these conditions and their treatments in athletic performance. Another important consideration in the older athlete is fluid ingestion and the increased risk of dehydration. There is evidence that physical exercise reduces pain in osteoarthritis and enhances physical function of affected joints...
November 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/29030343/carbohydrate-restriction-with-postmeal-walking-effectively-mitigates-postprandial-hyperglycemia-and-improves-endothelial-function-in-type-2-diabetes
#16
Monique Emily Francois, Etienne Myette-Cote, Tyler Daniel Bammert, Cody Durrer, Helena Neudorf, Christopher A DeSouza, Jonathan Peter Little
Postprandial hyperglycemia has deleterious effects on endothelial function. Restricting carbohydrate intake and postmeal walking have each been shown to reduce postprandial hyperglycemia but their combination and subsequent effects on endothelial function have not been investigated. Here, we sought to examine the effect of blunting postprandial hyperglycemia by following a low-carbohydrate diet, with or without postmeal walking exercise, on markers of vascular health in type 2 diabetes (T2D). In a randomized crossover design, individuals with T2D (N=11) completed three four-day controlled diet interventions consisting of i) low-carbohydrate diet alone (LC), ii) low-carbohydrate diet with 15-minute postmeal walks (LC+Ex), and iii) Low-fat control diet (CON)...
October 13, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29029950/survival-of-idiopathic-pulmonary-arterial-hypertension-patients-in-the-modern-era-in-australia-and-new-zealand
#17
Geoff Strange, Edmund M Lau, Eleni Giannoulatou, Carolyn Corrigan, Eugene Kotlyar, Fiona Kermeen, Trevor Williams, David S Celermajer, Nathan Dwyer, Helen Whitford, Jeremy P Wrobel, John Feenstra, Melanie Lavender, Kenneth Whyte, Nicholas Collins, Peter Steele, Susanna Proudman, Vivek Thakkar, Dominic Keating, Anne Keogh
BACKGROUND: Epidemiology and treatment strategies continue to evolve in pulmonary arterial hypertension (PAH). We sought to define the characteristics and survival of patients with idiopathic, heritable and drug-induced PAH in the current management era. METHODS: Consecutive cases of idiopathic, heritable and drug-induced PAH were prospectively enrolled into an Australian and New Zealand Registry. RESULTS: Between January 2012 and December 2016, a total of 220 incident cases were enrolled (mean age 57...
September 20, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29027533/factors-associated-with-circulating-concentrations-of-irisin-in-the-general-population-cohort-of-the-abcd-study
#18
S Buscemi, D Corleo, S Vasto, C Buscemi, M F Massenti, D Nuzzo, G Lucisano, A M Barile, G Rosafio, V Maniaci, C Giordano
BACKGROUND: Animal studies have shown that irisin is a myokine secreted following physical exercise, and that it induces the remodeling of white adipose tissue toward brown adipose tissue. Therefore, a protective role of irisin against obesity, diabetes, and other metabolic and cardiovascular conditions has been hypothesized. However, data in humans are contradictory and few data are available concerning the general population. AIMS: We aimed to evaluate the association between serum irisin concentrations and habitual physical activity, as well as other metabolic and cardiovascular factors in a general population in a Mediterranean area...
October 13, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29026833/primary-prevention-of-cardiovascular-disease-in-older-adults-in-china
#19
REVIEW
Jian Yong, Dong Lin, Xue-Rui Tan
Over the past two decades, the percentage of Chinese who is 60 years or older has increased from 5.2% in 1995 to 10.5% in 2015. Approximately 16% of the population in China was 60 years old and above in 2015. Since 1990, cardiovascular disease (CVD) has been the leading cause of death in China. Cardiovascular medications of older adults are usually more complicated than younger age groups due to polypharmacy, the presence of comorbidities and more susceptible to treatment-related adverse outcomes. Therefore, effective primary prevention of CVD for older adults is important in sustaining the health of older adults and reducing the burden of the healthcare system...
September 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29025508/discrepancy-in-motivation-for-weight-loss-and-exercise-in-rural-patients
#20
Jacob C Warren, K Bryant Smalley, K Nikki Barefoot
OBJECTIVES: We explored the extent to which discrepancy between motivation for weight loss and exercise is related to obesity among rural patients with chronic disease, and identified the psychosocial correlates of this discrepancy. METHODS: 497 patients with diabetes and/or hypertension were recruited from a network of Federally Qualified Health Centers in the rural South and completed a battery of assessments. RESULTS: Most persons in the sample (83...
November 1, 2017: American Journal of Health Behavior
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