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https://www.readbyqxmd.com/read/28822025/cardiovascular-health-in-st-louis-bosnian-americans
#1
Maximillian T Bourdillon, Asad S Akhter, Dejan Vrtikapa, Amer Avdagic, Marc A McNeese, Richard Lee, Dawn S Hui
In Bosnia and Herzegovina, cardiovascular disease accounts for nearly 50% of deaths. Cardiovascular health of resettled Bosnian-Americans has not been well-characterized. Our study aimed to quantify cardiovascular risk in Bosnian-Americans in St. Louis, the largest non-European center of resettlement. Seven community screenings focused on Bosnian-Americans were held. Cardiovascular risk was calculated to stratify individuals into low (<10%), moderate (10-20%), and high (>20%) risk. Those with self-reported coronary heart disease (CHD) or risk equivalent were considered high-risk...
August 18, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28821320/reduced-neural-responses-to-food-cues-might-contribute-to-the-anorexigenic-effect-of-acute-exercise-observed-in-obese-but-not-lean-adolescents
#2
S N Fearnbach, L Silvert, B Pereira, Y Boirie, M Duclos, K L Keller, D Thivel
Acute exercise has been found to reduce subsequent energy intake in obese adolescents. Although it has been suggested that some neural pathways are involved in this post-exercise energy intake regulation, it remains unknown whether the post-exercise attentional response to food cues differs as a function of weight status. We hypothesize that there will be a reduction in the neural response to food cues as a result of exercise in obese adolescents, but not in their lean counterparts. Fourteen obese and 14 lean adolescent boys (12-15 years) were randomized (within-subjects design) to remain seated (CON) or to exercise 45 minutes at 65% of their maximal capacities (EX)...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28819990/effects-of-maternal-high-fat-diet-and-sedentary-lifestyle-on-susceptibility-of-adult-offspring-to-ozone-exposure-in-rats
#3
C J Gordon, P M Phillips, A F M Johnstone, J Schmid, M C Schladweiler, A Ledbetter, S J Snow, U P Kodavanti
Epidemiological and experimental data suggest that obesity exacerbates the health effects of air pollutants such as ozone (O3). Maternal inactivity and calorically rich diets lead to offspring that show signs of obesity. Exacerbated O3 susceptibility of offspring could thus be manifested by maternal obesity. Thirty-day-old female Long-Evans rats were fed a control (CD) or high-fat (HF) (60% calories) diet for 6 wks and then bred. GD1 rats were then housed with a running wheel (RW) or without a wheel (SED) until parturition, creating four groups of offspring: CD-SED, CD-RW, HF-SED and HF-RW...
August 18, 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/28818415/modifiable-lifestyle-risk-factors-and-incident-diabetes-in-african-americans
#4
Joshua J Joseph, Justin B Echouffo-Tcheugui, Sameera A Talegawkar, Valery S Effoe, Victoria Okhomina, Mercedes R Carnethon, Willa A Hsueh, Sherita H Golden
INTRODUCTION: The associations of modifiable lifestyle risk factors with incident diabetes are not well investigated in African Americans (AAs). This study investigated the association of modifiable lifestyle risk factors (exercise, diet, smoking, TV watching, and sleep-disordered breathing burden) with incident diabetes among AAs. METHODS: Modifiable lifestyle risk factors were characterized among 3,252 AAs in the Jackson Heart Study who were free of diabetes at baseline (2000-2004) using baseline questionnaires and combined into risk factor categories: poor (0-3 points), average (4-7 points), and optimal (8-11 points)...
August 14, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28818324/the-treatment-of-segmental-tibial-fractures-does-patient-preference-differ-from-surgeon-choice
#5
Z Little, T O Smith, S E McMahon, C Cooper, A Trompeter, M Pearse, S Britten, B Rogers, H Sharma, B Narayan, M Costa, D J Beard, C B Hing
INTRODUCTION: Segmental tibial fractures are complex injuries with a prolonged recovery time. Current definitive treatment options include intramedullary fixation or a circular external fixator. However, there is uncertainty as to which surgical option is preferable and there are no sufficiently rigorous multi-centre trials that have answered this question. The objective of this study was to determine whether patient and surgeon opinion was permissive for a randomised controlled trial (RCT) comparing intramedullary nailing to the application of a circular external fixator...
August 9, 2017: Injury
https://www.readbyqxmd.com/read/28818261/contemporary-medical-therapies-of-atherosclerotic-carotid-artery-disease
#6
Suk F Cheng, Martin M Brown
Contemporary medical therapy consists of identification and treatment of all patient-modifiable vascular risk factors. Specific atherosclerotic disease therapies are designed to reduce the risk of thrombosis, and the disease progression in order to reduce the risk of future cardiovascular events. Contemporary medical management emphasizes the need to support the patient in achieving lifestyle modifications and to adjust medication to achieve individualized target values for specific quantifiable risk factors...
March 2017: Seminars in Vascular Surgery
https://www.readbyqxmd.com/read/28817856/back-to-basics-the-effect-of-healthy-diet-and-exercise-on-chronic-disease-management
#7
Robert L Allison
INTRODUCTION: The increase in obesity rates in the U.S. and other less developed industrial countries have led to a worldwide epidemic of chronic disease states. Increased obesity rates are implicated in the treatment failures for illnesses such as coronary artery disease, diabetes, heart failure, hypertension and cancer. Effective prevention of obesity through diet and exercise contributes to the successful medical management of multiple chronic disease states. OBJECTIVE: Review the last 10 years of literature (2006-2016) on the effects of diet and exercise as they relate to the prevention of chronic disease...
2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28815987/health-related-quality-of-life-in-randomized-controlled-trials-of-lorcaserin-for-obesity-management-what-mediates-improvement
#8
R L Kolotkin, R D Crosby, Z Wang
Lorcaserin, plus diet and exercise, has demonstrated significant weight loss and improved cardiometabolic parameters vs. placebo in patients with overweight/obesity in three randomized, placebo-controlled trials. We examined whether lorcaserin is also associated with greater improvements in health-related quality of life (HRQOL) and whether these improvements are wholly attributable to weight loss. Pooled data from Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM), Behavioral Modification and Lorcaserin Second Study for Obesity Management (BLOSSOM) and BLOOM-Diabetes Mellitus (BLOOM-DM) trials were analysed (n = 5624)...
August 17, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28814401/effects-of-protein-supplementation-combined-with-resistance-exercise-on-body-composition-and-physical-function-in-older-adults-a-systematic-review-and-meta-analysis
#9
Chun-De Liao, Jau-Yih Tsauo, Yen-Tzu Wu, Chin-Pao Cheng, Hui-Chuen Chen, Yi-Ching Huang, Hung-Chou Chen, Tsan-Hon Liou
Background: Overweight and obese older people face a high risk of muscle loss and impaired physical function, which may contribute to sarcopenic obesity. Resistance exercise training (RET) has a beneficial effect on muscle protein synthesis and can be augmented by protein supplementation (PS). However, whether body weight affects the augmentation of muscular and functional performance in response to PS in older people undergoing RET remains unclear.Objective: This study was conducted to identify the effects of PS on the body composition and physical function of older people undergoing RET...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28814391/filling-the-void-a-role-for-exercise-induced-bdnf-and-brain-amyloid-precursor-protein-processing
#10
Rebecca Ek MacPherson
Inactivity, obesity, and insulin resistance are significant risk factors for the development of Alzheimer's disease (AD). Several studies have demonstrated that diet induced obesity, inactivity, and insulin resistance exacerbates neuropathological hallmarks of AD. The aggregation of beta-amyloid peptides is one of these hallmarks. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the rate-limiting enzyme in amyloid precursor protein (APP) processing, leading to beta-amyloid peptide formation...
August 16, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28811737/learning-and-developing-individual-exercise-skills-l-a-d-i-e-s-for-a-better-life-a-church-based-physical-activity-intervention-baseline-participant-characteristics
#11
Melicia C Whitt-Glover, Moses V Goldmon, Ziya Gizlice, Daniel P Heil, Njeri Karanja
OBJECTIVE: Physical activity (PA) is beneficial for health, yet most African American women do not achieve recommended levels. Successful, sustainable strategies could help to address disparities in health outcomes associated with low levels of PA. The Learning and Developing Individual Exercise Skills (L.A.D.I.E.S.) for a Better Life study compared a faith-based and a secular intervention for increasing PA with a self-guided control group. DESIGN SETTING AND PARTICIPANTS: This cluster randomized, controlled trial was conducted from 2010 - 2011 in African American churches (n=31) in suburban North Carolina...
2017: Ethnicity & Disease
https://www.readbyqxmd.com/read/28810972/when-military-fitness-standards-no-longer-apply-the-high-prevalence-of-metabolic-syndrome-in-recent-air-force-retirees
#12
Marcus M Cranston, Mark W True, Jana L Wardian, Rishawn M Carriere, Tom J Sauerwein
BACKGROUND: Metabolic syndrome (MetS) is strongly associated with cardiovascular disease. With MetS prevalence rates increasing in the U.S. population, prevention efforts have largely focused on diet and exercise interventions. Before retirement, military service members have met fitness requirements for at least 20 years, and have lower MetS rates compared to age-matched U.S. population controls (23.4% vs. 39.0%), which suggests a protective effect of the lifestyle associated with military service...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28809195/pok%C3%A3-mon-go-why-augmented-reality-games-offer-insights-for-enhancing-public-health-interventions-on-obesity-related-diseases
#13
Ming Chao Wong, Paul Turner, Kate MacIntyre, Kwang Chien Yee
Stimulating widespread interests of the population to participate in behavioural changes through information and technology has been an aim of much health informatics research. The recent widespread participation of the augmented reality game Pokémon Go which encourages exercises, provides significant insights into the potential of information technology to improve healthcare intervention on obesity-related disease. Does Pokémon Go point to another way of achieving health benefits using mobile devices? This paper analyses the features of Pokémon Go in relation to potential health benefits...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28807645/a-behavioral-weight-loss-program-and-non-urinary-incontinence-lower-urinary-tract-symptoms-in-overweight-and-obese-women-with-urinary-incontinence-a-secondary-data-analysis-of-the-program-to-reduce-incontinence-by-diet-and-exercise-pride
#14
Benjamin N Breyer, Jennifer M Creasman, Holly E Richter, Deborah Myers, Kathryn L Burgio, Rena R Wing, Delia Smith West, John W Kusek, Leslee L Subak
AIMS: To determine whether a behavioral weight reduction intervention improves non-urinary incontinence (UI) lower urinary tract storage symptoms (LUTS) including urinary frequency, nocturia, urgency, at 6 months compared to a structured education program (control group) among overweight and obese women with UI. METHODS: The Program to Reduce Incontinence by Diet and Exercise (PRIDE) was a randomized clinical trial of 338 overweight or obese women with UI. Participants were randomized to 6-month behavioral weight loss intervention (N=226) or control (N=112)...
August 11, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28803380/aerobic-interval-training-reduces-vascular-resistances-during-submaximal-exercise-in-obese-metabolic-syndrome-individuals
#15
Ricardo Mora-Rodriguez, V E Fernandez-Elias, F Morales-Palomo, J G Pallares, M Ramirez-Jimenez, J F Ortega
PURPOSE: The aim of this study was to determine the effects of high-intensity aerobic interval training (AIT) on exercise hemodynamics in metabolic syndrome (MetS) volunteers. METHODS: Thirty-eight, MetS participants were randomly assigned to a training (TRAIN) or to a non-training control (CONT) group. TRAIN consisted of stationary interval cycling alternating bouts at 70-90% of maximal heart rate during 45 min day(-1) for 6 months. RESULTS: CONT maintained baseline physical activity and no changes in cardiovascular function or MetS factors were detected...
August 12, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28801940/examining-the-association-between-depression-and-obesity-during-a-weight-management-programme
#16
N R Fuller, J Burns, A Sainsbury, S Horsfield, F da Luz, S Zhang, G Denyer, T P Markovic, I D Caterson
The prevalence of depression in those with obesity is reported to be as high as double that in individuals of normal weight. There is potentially a bi-directional relationship between obesity and depression. Some research has suggested that depression results in weight gain and obesity, and other studies have suggested that those with obesity are more likely to develop depression at a later stage. The aim of this study was to investigate the association of depression symptoms with weight change over a 12-month study...
August 11, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28801668/exercise-leads-to-unfavourable-cardiac-remodelling-and-enhanced-metabolic-homeostasis-in-obese-mice-with-cardiac-and-skeletal-muscle-autophagy-deficiency
#17
Zhen Yan, Ana Kronemberger, Jay Blomme, Jarrod A Call, Hannah M Caster, Renata O Pereira, Henan Zhao, Vitor U de Melo, Rhianna C Laker, Mei Zhang, Vitor A Lira
Autophagy is stimulated by exercise in several tissues; yet the role of skeletal and cardiac muscle-specific autophagy on the benefits of exercise training remains incompletely understood. Here, we determined the metabolic impact of exercise training in obese mice with cardiac and skeletal muscle disruption of the Autophagy related 7 gene (Atg7(h&mKO)). Muscle autophagy deficiency did not affect glucose clearance and exercise capacity in lean adult mice. High-fat diet in sedentary mice led to endoplasmic reticulum stress and aberrant mitochondrial protein expression in autophagy-deficient skeletal and cardiac muscles...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28801525/exercise-of-obese-mice-induces-cardioprotection-and-oxygen-sparing-in-hearts-exposed-to-high-fat-load
#18
Neoma T Boardman, Anne Dragøy Hafstad, Jim Lund, Line Rossvoll, Ellen Aasum
Exercise training is a potent, therapeutic approach in obesity and diabetes that exerts protective effects against development of diabetic cardiomyopathy and ischemic-injury. Acute increases in circulating fatty acids (FAs) during an ischemic insult can challenge the heart, as high FA-load is considered to have adverse cardiac effects. In the present study, we tested the hypothesis that exercise-induced cardiac effects in diet-induced obese mice are abrogated by an acute high FA-load. Diet-induced obese mice were fed a high-fat diet (HFD) for 20 weeks...
August 11, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28801068/lepr-polymorphism-may-affect-energy-balance-during-weight-loss-among-brazilians-obese-adolescents
#19
Flávia Campos Corgosinho, Sandro Soares Almeida, Lian Tock, João Bosco Pesquero, Ronaldo Carvalho Araújo, Ana Paula Grotti Clemente, Bárbara Dal'Molin Netto, Raquel Munhoz da Silveira Campos, Deborah Cristina Landi Masquio, Joana Pereira de Carvalho Ferreira, Priscila de Lima Sanches, Aline de Piano Ganen, Marcelo Macedo Rogero, Lila Missae Oyama, Sergio Tufik, Marco Túlio de Mello, Ana Raimunda Dâmaso
OBJECTIVE: Leptin is an adipokine released mainly by adipose tissue, with many functions including regulation of energy balance. However, little is known about the effect of LEPR polymorphism on orexigenic and anorexigenic neuropeptides. Thus, the aim of the present study is to verify the influence of LEPR polymorphism (rs2767485) on serum orexigenic (NPY, MCH and AgRP) and anorexigenic (Leptin and α-MSH) neuropeptides levels among obese adolescents submitted to 1year of multicomponent weight loss therapy...
August 2, 2017: Neuropeptides
https://www.readbyqxmd.com/read/28801055/therapy-with-mesenchymal-stromal-cells-or-conditioned-medium-reverse-cardiac-alterations-in-a-high-fat-diet-induced-obesity-model
#20
P S Daltro, B C Barreto, P G Silva, P Chenaud Neto, P H F Sousa Filho, D Santana Neta, G B Carvalho, D N Silva, B D Paredes, A C de Alcantara, L A R Freitas, R D Couto, R R Santos, B S F Souza, M B P Soares, S G Macambira
BACKGROUND: Obesity is associated with numerous cardiac complications, including arrhythmias, cardiac fibrosis, remodeling and heart failure. Here we evaluated the therapeutic potential of mesenchymal stromal cells (MSCs) and their conditioned medium (CM) to treat cardiac complications in a mouse model of high-fat diet (HFD)-induced obesity. METHODS: After obesity induction and HFD withdrawal, obese mice were treated with MSCs, CM or vehicle. Cardiac function was assessed using electrocardiography, echocardiography and treadmill test...
August 8, 2017: Cytotherapy
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