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https://www.readbyqxmd.com/read/28320159/prevalence-of-peripheral-neuropathy-and-associated-factors-in-hiv-infected-patients
#1
Maria Luiza Areal Corrêa de Sá E Benevides, Sérgio Beduschi Filho, Rodrigo Debona, Eduardo Novaes Costa Bergamaschi, Jean Costa Nunes
The progress on HIV infection treatment has allowed a longer survival for HIV-infected patients. However, chronic comorbidities are emerging. Peripheral Neuropathy (PN) represents one of the most prevalent neurologic disorders among these patients, and comprehensive studies may contribute to a reduction in the morbidity of this condition. This is a cross-sectional analytic study conducted in a tertiary referral hospital in southern Brazil. This study investigates the prevalence of PN among HIV-infected patients and associated demographic, clinical and laboratory variables...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28320132/early-markers-of-kidney-dysfunction-and-cognitive-impairment-among-older-adults
#2
Yudan Wei, Yinan Kevin Wei, Jianmin Zhu
BACKGROUND: Age-related decline in kidney function can be an important risk factor for cognitive impairment in older adults. In this study, we examined several kidney function measures for the association with cognitive function in older adults in hope to identify early and sensitive markers that can be used for the detection or screening for cognitive impairment. METHODS: A total of 1982 older participants (aged ≥60years) in the 1999-2002 National Health and Nutrition Examination Survey was analyzed for the association between kidney function and cognitive impairment using multivariate logistic regression and general linear models...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28320073/a-model-linking-video-gaming-sleep-quality-sweet-drinks-consumption-and-obesity-among-children-and-youth
#3
O Turel, A Romashkin, K M Morrison
There is a growing need to curb paediatric obesity. The aim of this study is to untangle associations between video-game-use attributes and obesity as a first step towards identifying and examining possible interventions. Cross-sectional time-lagged cohort study was employed using parent-child surveys (t1) and objective physical activity and physiological measures (t2) from 125 children/adolescents (mean age = 13.06, 9-17-year-olds) who play video games, recruited from two clinics at a Canadian academic children's hospital...
March 20, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28320071/adherence-to-national-exercise-guidelines-by-patients-attending-emergency-departments-a-multi-site-survey
#4
Paul Berlingeri, Neil Cunningham, David McD Taylor, Jonathan Knott, Daniel McLean, Rex Gavan, Luke Plant, Hayley Chen, Tracey Weiland
OBJECTIVE: The proportion of adults in Australia meeting or exceeding the national guidelines for physical activity has remained relatively static over the past 10 years. The research objective was to measure self-reported physical activity and sedentary behaviour among ED patients in accordance with Australia's current physical activity and sedentary behaviour guidelines, revised in 2014. METHODS: A convenience sample of participants was recruited from three EDs in Melbourne between February and May 2016...
March 20, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/28320057/psychiatric-diagnoses-and-medication-treatment-among-patients-presenting-for-paediatric-weight-management-associations-with-adiposity-aerobic-fitness-and-cardiometabolic-health
#5
J M Tucker, A Cadieux, K Culver, L Smith, W Stratbucker
We compared anthropometry, cardiometabolic risk and aerobic fitness among obese youth in weight management who were diagnosed with one or more psychiatric disorders (PD), with (PD+M) or without (PD-M) a prescribed psychotropic medication with those with no PD (NPD). Physical measures were evaluated at baseline, and psychiatric diagnoses and related medications were identified from medical records. Of 99 patients 64 (65%) had a diagnosed PD, and of those, 23 (36%) had a related medication (PD+M). Compared to NPD, PD-M had a higher body mass index (BMI) (P = 0...
March 20, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28320046/increased-insulin-resistance-and-glucagon-levels-in-mild-inactive-systemic-lupus-patients-despite-normal-glucose-tolerance
#6
Cíntia Nh Miyake, Bruno Gualano, Wagner S Dantas, Renato T Pereira, William Neves, Vanessa O Zambelli, Samuel K Shinjo, Rosa M Pereira, Elizabeth R Silva, Ana Lúcia Sá-Pinto, Eduardo Borba, Hamilton Roschel, Eloisa Bonfá, Fabiana B Benatti
OBJECTIVE: To assess insulin sensitivity in patients with systemic lupus erythematosus (SLE) in response to a meal tolerance test (MTT). METHODS: In this cross-sectional study, 33 adult females mild/inactive SLE and 16 age- and body mass index (BMI)-matched female healthy controls (CTRL) underwent a MTT and were assessed for insulin sensitivity and beta-cell function. Skeletal muscle protein expressions of total and membrane GLUT-4 were also evaluated (SLE, n=10; CTRL, n=5); muscle biopsies were performed after MTT...
March 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28319905/a-new-amplified-%C3%AF-shape-electrochemical-aptasensor-for-ultrasensitive-detection-of-aflatoxin-b1
#7
Khalil Abnous, Noor Mohammad Danesh, Mona Alibolandi, Mohammad Ramezani, Ahmad Sarreshtehdar Emrani, Reza Zolfaghari, Seyed Mohammad Taghdisi
There is a prompt need for determination of aflatoxin B1 (AFB1) in food products to avoid distribution and consumption of contaminated food products. In this study, an accurate electrochemical sensing strategy was presented for detection of AFB1 based on aptamer (Apt)-complementary strands of aptamer (CSs) complex which forms a π-shape structure on the surface of electrode and exonuclease I (Exo I). The presence of π-shape structure as a double-layer physical barrier allowed detection of AFB1 with high sensitivity...
March 17, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28319868/synthesis-characterization-of-amide-substituted-dexibuprofen-derivatives-and-their-spectral-voltammetric-and-docking-investigations-for-dna-binding-interactions
#8
Nasima Arshad, Muhammad Zafran, Zaman Ashraf, Fouzia Perveen
Three amide derivatives - methyl-2-[2-(4-isobutylphenyl)propanamido]propanoate (Dex-2), methyl 2-[2-(4-isobutylphenyl) propanamido]-3-phenylpropanoate (Dex-3) and methyl 2-[2-(4-isobutylphenyl)-propanamido]-4-methylpentanoate (Dex-4) of dexibuprofen (Dex-1) 2-(4-isobutylphenyl)propanoic acid were synthesized and conformed for structures by physical data and spectral analysis. Further, all the compounds were studied for their binding with ds.DNA through experimental (UV-visible/and fluorescence spectroscopy, cyclic voltammetry) and theoretical (molecular docking) techniques...
March 3, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28319867/phototherapeutic-spectrum-expansion-through-synergistic-effect-of-mesoporous-silica-trio-nanohybrids-against-antibiotic-resistant-gram-negative-bacterium
#9
Yaswanth Kuthati, Ranjith Kumar Kankala, Prabhakar Busa, Shi-Xiang Lin, Jin-Pei Deng, Chung-Yuan Mou, Chia-Hung Lee
The extensive impact of antibiotic resistance has led to the exploration of new anti-bacterial modalities. We designed copper impregnated mesoporous silica nanoparticles (Cu-MSN) with immobilizing silver nanoparticles (SNPs) to apply photodynamic inactivation (PDI) of antibiotic-resistant E. coli. SNPs were decorated over the Cu-MSN surfaces by coordination of silver ions on diamine-functionalized Cu-MSN and further reduced to silver nanoparticles with formalin. We demonstrate that silver is capable of sensitizing the gram-negative bacteria E...
March 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28319858/identifying-adverse-effects-of-area-based-health-policy-an-ethnographic-study-of-a-deprived-neighbourhood-in-england
#10
Oli Williams
Health interventions commonly have adverse effects. Addressing these could significantly improve health outcomes. This paper addresses an adverse effect common in the promotion of health behaviours: exacerbation of health inequalities between low- and high-socioeconomic groups. Health behaviours - particularly, physical activity - are positioned within the context of social inequality and the inequitable spatial distribution of resources. Area-based health policy that targets deprived areas is assessed for its capacity to promote health behaviours without exacerbating inequality...
March 17, 2017: Health & Place
https://www.readbyqxmd.com/read/28319795/theoretical-study-of-thieno-thiophene-based-low-band-gap-copolymers-and-substituent-effect-on-the-optoelectronic-properties-of-them
#11
Mehri Javan Khoshkholgh, Mohammad Reza Abolhassani, Farah Marsusi
This paper studies donor-acceptor systems which incorporate benzodithiophene (BDT), benzodifuran (BDF) and benzodipyrrole (BDP) units as the electron-rich monomer with TT unit representing the electron-deficient monomer. This research is based on employing density functional theory (DFT) and time-dependent DFT (TD-DFT). The highest occupied molecular orbitals (HOMO) and the lowest unoccupied molecular orbitals (LUMO), HOMO-LUMO gaps and dihedral-angles of these copolymers were calculated using oligomer extrapolation technique and periodic boundary condition (PBC) method...
March 7, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28319786/lower-cardiorespiratory-fitness-is-associated-with-more-time-spent-sedentary-in-first-episode-psychosis-a-pilot-study
#12
Davy Vancampfort, Marc De Hert, Inez Myin-Germeys, Ruud van Winkel, Joseph Firth, Tine Van Damme, Michel Probst
Patients with a psychotic disorder show lower cardiorespiratory fitness and higher mortality rates compared to healthy individuals. The aim of this cross-sectional study was to explore whether in patients with first-episode psychosis a low cardiorespiratory fitness is associated with decreased physical activity and increased sedentary levels. Twenty-nine outpatients (21 men; 22.8±5.1 years) performed a maximal exercise test to assess their maximum oxygen uptake (VO2max), wore a Senswear armband for five consecutive days and were assessed with the Positive and Negative Syndrome Scale...
March 14, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28319734/novel-mechanical-impact-simulator-designed-to-generate-clinically-relevant-anterior-cruciate-ligament-ruptures
#13
Nathaniel A Bates, Nathan D Schilaty, Christopher V Nagelli, Aaron J Krych, Timothy E Hewett
BACKGROUND: Over 250,000 anterior cruciate ligament ruptures occur each year; therefore, it is important to understand the underlying mechanisms of these injuries. The objective of the current investigation was to develop and analyze an impact test device that consistently produces anterior cruciate ligament failure in a clinically relevant manner. METHOD: A mechanical impact simulator was developed to simulate the ground reaction force impulse generated from landing in a physiologic and clinically relevant manner...
March 10, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28319718/effect-of-environmental-exposure-on-charcoal-density-and-porosity-in-a-boreal-forest
#14
Xiaodong Gao, Laura E Driver, Isabella Kasin, Caroline A Masiello, Lacey A Pyle, Brandon Dugan, Mikael Ohlson
Although charcoal's density and porosity shape its environmental roles (e.g. controlling its landscape movement and determining the internal pore space available as microbial habitat), the rate of change of these properties in the environment remains largely unknown. With time, charcoal pores may fill or charcoal particles may shatter, altering the ecosystem services delivered. In this study we examined the effects of environmental exposure on the density and porosity of charcoals pyrolyzed at two different temperatures (350 and 520°C)...
March 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28319696/behavioral-activation-versus-physical-activity-via-the-internet-a-randomized-controlled-trial
#15
Markus B T Nyström, Andreas Stenling, Emma Sjöström, Gregory Neely, Philip Lindner, Peter Hassmén, Gerhard Andersson, Christopher Martell, Per Carlbring
BACKGROUND: A major problem today is that only about fifty percent of those affected by depression seeks help. One way to reach more sufferers would be by offering easily accessible internet based treatments. The purpose of this study was to compare/evaluate four therapist supported internet administered treatments. METHOD/RESULTS: Two hundred eighty six participants were included. The treatment period lasted twelve weeks, consisting of the following treatments: 1) physical activity without treatment rational, 2) physical activity with treatment rational, 3) behavioral activation without treatment rational and 4) behavioral activation with treatment rational...
March 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28319659/improving-computational-predictions-of-single-stranded-rna-tetramers-with-revised-%C3%AE-%C3%AE-torsional-parameters-for-the-amber-force-field
#16
David J Wales, Ilyas Yildirim
With current advancements in RNA based therapeutics, it is becoming crucial to utilize theoretical and computational methods to describe properly the physical properties of RNA molecules. NMR and X-ray crystallography are two powerful techniques for investigating structural properties. However, if the RNA molecules are complex or dynamic, these methods might not be adequate. For computational approaches, the quality of the force field will determine accuracy of our predictions. In this contribution, we revise the α/γ torsional parameters of RNA for amber force field using a model system representing an RNA dimer backbone...
March 20, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28319640/the-corneal-epithelial-barrier-and-its-developmental-role-in-isolating-corneal-epithelial-and-conjunctival-cells-from-one-another
#17
James K Kubilus, Carolina Zapater I Morales, Thomas F Linsenmayer
Purpose: During development, the corneal epithelium (CE) and the conjunctiva are derived from the surface ectoderm. Here we have examined how, during development, the cells of these two issues become isolated from each other. Methods: Epithelia from the anterior eyes of chicken embryos were labeled with the fluorescent, lipophilic dye, 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI). DiI was placed on the epithelial surface of the developing anterior eye and its diffusion was monitored by fluorescence microscopy...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28319611/functional-electronic-inversion-layers-at-ferroelectric-domain-walls
#18
J A Mundy, J Schaab, Y Kumagai, A Cano, M Stengel, I P Krug, D M Gottlob, H Dog Anay, M E Holtz, R Held, Z Yan, E Bourret, C M Schneider, D G Schlom, D A Muller, R Ramesh, N A Spaldin, D Meier
Ferroelectric domain walls hold great promise as functional two-dimensional materials because of their unusual electronic properties. Particularly intriguing are the so-called charged walls where a polarity mismatch causes local, diverging electrostatic potentials requiring charge compensation and hence a change in the electronic structure. These walls can exhibit significantly enhanced conductivity and serve as a circuit path. The development of all-domain-wall devices, however, also requires walls with controllable output to emulate electronic nano-components such as diodes and transistors...
March 20, 2017: Nature Materials
https://www.readbyqxmd.com/read/28319591/psychopathological-assessment-of-risk-of-restraint-in-acute-psychiatric-patients
#19
Federico Dazzi, Lorenzo Tarsitani, Michele Di Nunzio, Valeria Trincia, Gabriella Scifoni, Giuseppe Ducci
The study aims to identify independent predictors of physical restraint in acute psychiatric patients and to determine the predictive power of a risk assessment model centered on psychopathological dimensions. We included 1552 patients admitted to a psychiatric intensive care unit over a 5-year period. Patients were rated on the Brief Psychiatric Rating Scale (BPRS-E) at admission. Principal axis factoring (PAF) with varimax rotation was performed on BPRS-E items to identify psychopathological factors. Multiple logistic regression analysis was performed...
March 18, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28319590/endocannabinoid-and-mood-responses-to-exercise-in-adults-with-varying-activity-levels
#20
Angelique G Brellenthin, Kevin M Crombie, Cecilia J Hillard, Kelli F Koltyn
Acute aerobic exercise improves mood and activates the endocannabinoid (eCB) system in physically active individuals; however, both mood and eCB responses to exercise may vary based on habitual levels of physical activity. PURPOSE: To examine eCB and mood responses to prescribed and preferred exercise among individuals with low, moderate, and high levels of physical activity. METHODS: Thirty-six healthy adults (21±4yrs) were recruited from low (≤60min moderate-vigorous physical activity [MVPA]/wk), moderate (150-299min MVPA/wk), and high (≥300 MVPA/wk) physical activity groups...
March 18, 2017: Medicine and Science in Sports and Exercise
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