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abnormal pap smear

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https://www.readbyqxmd.com/read/29118476/age-and-pattern-of-pap-smear-abnormalities-implications-for-cervical-cancer-control-in-a-developing-country
#1
Adepiti Clement Akinfolarin, Ajenifuja Kayode Olusegun, Okunola Omoladun, G O Omoniyi-Esan, Uche Onwundiegu
Aim: To characterize the age and pattern of Pap smear abnormalities in a major teaching hospital in Southwestern Nigeria. Design: This is a review of medical records of patients that came for cervical cancer screening. Materials and Methods: The Pap smear results of women between May 2013 and April 2015 were retrieved. A total of 2048 Pap smear results were retrieved during the study period and analyzed with Statistical Package for Social Sciences (SPSS) version 20...
October 2017: Journal of Cytology
https://www.readbyqxmd.com/read/29103241/unexpected-significant-uterine-pathological-findings-at-vaginal-hysterectomy-despite-unremarkable-preoperative-workup
#2
Yossi Mizrachi, Samer Tannus, Jacob Bar, Ron Sagiv, Tally Levy, Alexander Condrea, Shimon Ginath
BACKGROUND: Several studies have addressed the issue of undetected uterine pathology in women undergoing hysterectomy for pelvic organ prolapse (POP). However, these studies differ largely with respect to the incidence of malignancy found, study population, and preoperative evaluation. OBJECTIVES: To assess the risk of unexpected pre-malignant and malignant uterine pathological findings after vaginal hysterectomy for POP repair, in a single medical center in Israel...
October 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29075548/histopathologic-and-cytologic-follow-up-in-high-risk-male-patients-with-unsatisfactory-anal-cytology
#3
Daniel J Zaccarini, Kamal K Khurana
OBJECTIVE: Anal cytology is being increasingly used as part of anal cancer screening in patients at high risk for anal neoplasia. Most studies in anal cytology have focused on correlating the abnormal anal Pap smear with histopathologic outcomes. The aim of this study was to document histopathologic or repeat anal cytology outcomes in patients with unsatisfactory cytology. MATERIALS AND METHODS: Unsatisfactory anal Pap tests in high risk male patients were correlated with follow-up histopathologic diagnoses or cytology...
2017: Pathology Research International
https://www.readbyqxmd.com/read/29038761/comparison-of-human-papillomavirus-hpv-detection-in-urine-and-cervical-swab-samples-using-the-hpv-genoarray-diagnostic-assay
#4
Pornjarim Nilyanimit, Jira Chansaenroj, Anant Karalak, Piyawat Laowahutanont, Pairoj Junyangdikul, Yong Poovorawan
Human papillomavirus (HPV) is the leading cause of cervical cancer. Urine-based HPV testing offers a simple and non-invasive method because of its increasing acceptance. A total of 164 pairs of cervical swab and urine samples from Thai women who underwent cervical cancer screening were used for HPV testing with HPV GenoArray Diagnostic Kits. The overall concordance percentage for HPV detection in the cervical swab and urine samples was 65.2%. The HPV genotypes most commonly detected were HPV16 and HPV18. An analysis of the urine samples and a second analysis of the cervical swab samples showed that the differences in the overall HPV detection rate between women with normal and abnormal cytology were not significant (p > 0...
2017: PeerJ
https://www.readbyqxmd.com/read/29034324/a-review-of-epidemiologic-studies-of-the-health-of-gulf-war-women-veterans
#5
Steven S Coughlin, Maxine Krengel, Kimberly Sullivan, Penny F Pierce, Vahé Heboyan, Lt Col Candy Wilson
INTRODUCTION: In the 25 years since the 1990-1991 Gulf War (GW), studies have evaluated Gulf War Illness (GWI), sometimes referred to as medically unexplained multi symptom illness, and other medical and neurological conditions in women GW veterans. MATERIALS AND METHODS: In this article, we review epidemiologic studies of the health of women who served in the 1990-1991 GW based upon bibliographic searches in PubMed and CINAHL with relevant search terms through September 2015...
2017: Journal of Environment and Health Sciences
https://www.readbyqxmd.com/read/28990460/amplification-of-specific-chromosomal-regions-assessed-by-fluorescent-in-situ-hybridization-on-pap-smears-to-be-added-as-screening-tool-for-identifying-women-at-risk-of-progressing-to-cervical-cancer
#6
Pavani Upendram, Shubhi Sahni, Khaliq Mohiuddin, Subhadra Poornima, Bhanumathy Gourishankar, Kiran Kumar Vattam, Pavani Boddala, E Jayashankar, Shakera Mohiuddin, Vasundhara Kamineni, Vasavi Mohan, Jane Houldsworth, Qurratulain Hasan
Cervical carcinoma is a frequent malignancy in developing countries despite being a preventable disease. For the first time, four screening tests were used simultaneously for identifying women with a risk of developing cervical cancer, to help clinicians and policy makers to implement the best strategy for reducing the burden of this disease. Women visiting a hospital in India were enrolled after institutional ethics clearance and informed consent. Visual inspection using acetic acid and Pap smear tests were performed on 2683 women, and 104 had abnormal cytology: atypical squamous cells of undetermined significance (n = 29), low-grade squamous intraepithelial lesion (n = 41), high-grade squamous intraepithelial lesion (n = 17), and squamous cell carcinoma (n = 17)...
October 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28974850/difference-between-cryotherapy-and-follow-up-low-grade-squamous-lesion-of-cervix-uteri
#7
Mahira Jahic, Elmir Jahic, Mirsada Mulavdic, Azra Hadzimehmedovic
INTRODUCTION: Cervical cancer can be successfully prevented by effective treatment. AIM: Analyse of success of cryotherapy in LSIL and ASCUS. MATERIALS ET METHODS: In retrospective study between January 2016 to March 2017, 3244 PAP test were analysed. 257 patients who had been diagnosed with LSIL and ASCUS from PAP smear were divided in two groups: women who had HPV positive, colposcopic positive and cytologic finding of LSIL or ASCUS treathed with cryotherapy and women with LSIL, ASCUS and negative colposcopy...
August 2017: Medical Archives
https://www.readbyqxmd.com/read/28960293/prevalence-risk-factors-and-pregnancy-outcomes-of-cervical-cell-abnormalities-in-the-puerperium-in-a-hyperendemic-hiv-setting
#8
Hopolang C Maise, Dhayendre Moodley, Motshedisi Sebitloane, Suzanne Maman, Benn Sartorius
OBJECTIVE: To investigate the impact of cervical cell abnormalities detected in the puerperium in association with HIV-1 infection on pregnancy outcomes. METHODS: The present study was a secondary data analysis of pregnancy outcomes, Pap smear results, HIV results, and participant demography from a behavioral intervention randomized controlled trial of 1480 pregnant women aged 18 years or more conducted at a periurban primary health clinic in South Africa during 2008-2010...
September 28, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28952272/screening-cervical-cancer-by-the-pap-test-%C3%A2-relevance-of-age-ranges-recommended-by-the-brazilian-programme-for-prevention-and-control
#9
Diogo Do Nascimento Franco, Adriana Cunha Vargas Tomáz, Angela Andréia Franca Gravena, Sandra Marisa Pelloso, Márcia Edilaine Lopes Consolaro
Objective: To evaluate screening by the Papanicolaou smear (Pap) and the frequency of cervical abnormalities in the age range recommended by the Brazilian programme for prevention and control of cervical cancer (CC) in the years 2012 and 2013 in a high prevalence city. Methods: This retrospective study covered results of Pap examinations performed on women aged ≥12 years residing in urban areas of the city of Maringá, Paraná in Brazil. The examinations were performed in the years 2012 and 2013 for the System of Public Health (SPH) which maintains a city database...
September 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28929252/knowledge-about-cervical-cancer-risk-factors-and-practices-of-pap-testing-among-turkish-immigrant-women-in-the-united-states
#10
Aynur Uysal Toraman, Nilufer Yildirim
The objective of this study was to examine knowledge about cervical cancer risk factors and practices of Pap testing among female Turkish immigrants in the state of Florida in the United States of America (USA). This descriptive study was conducted between April and September 2012. The study sampling was consist of 156 Turkish women living in the state of Florida. A questionnaire-based survey was conducted among the population of Turkish immigrant women. On the survey form comprised of a total of 37 questions and three sections there are questions pertaining to the socio-demographic characteristics of the individuals, their knowledge on the cervical cancer risk factors and their approach to getting Pap smear tests...
September 19, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28901302/the-clinical-application-of-hpv-e6-e7-mrna-testing-in-triaging-women-with-atypical-squamous-cells-of-undetermined-significance-or-low-grade-squamous-intra-epithelial-lesion-pap-smear-a-meta-analysis
#11
REVIEW
Li Yang, Yuanhang Zhu, Yang Bai, Xiaoan Zhang, Chenchen Ren
OBJECTIVE: The aim is to evaluate the clinical application value and correlation with cervical lesions' progression of human papillomavirus (HPV) E6/E7 mRNA test in women with atypical squamous cells of undetermined significance (ASCUS/borderline) or low-grade squamous intraepithelial lesions (LSILs/mild dyskaryosis) cytological abnormalities. METHODS: A meta-analysis was conduct by searching China National Knowledge Infrastructure (1979-2016), Wanfang Date (1998-2016), VIP (1989-2016), PubMed (1950-2016), Web of Science (1950-2016) and Elsevier Science Direct (1998-2016), for studies on effect of HPV E6/E7 mRNA detection in women with ASCUS/LSIL/dyskaryosis...
2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28888068/thymic-enteric-type-adenocarcinoma-a-case-report-with-cytological-features
#12
Marie Tamai, Mitsuaki Ishida, Yusuke Ebisu, Hisashi Okamoto, Chika Miyasaka, Chisato Ohe, Yoshiko Uemura, Tomohito Saito, Tomohiro Murakawa, Koji Tsuta
Primary thymic adenocarcinoma is an extremely rare tumor, and thymic enteric type adenocarcinoma has recently been proposed as a distinct pathological entity. Herein, we report the first cytological description of thymic enteric type adenocarcinoma. A 29-year-old Japanese female without a significant past medical history was found to have an abnormal chest shadow. Chest computed tomography demonstrated a well-circumscribed tumor in the anterior mediastinum, and thymectomy was performed. The Papanicolaou staining of the touch smear of the resected tumor demonstrated tightly cohesive epithelial cell clusters in a necrotic background...
September 9, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28873092/effect-of-cervical-cancer-education-and-provider-recommendation-for-screening-on-screening-rates-a-systematic-review-and-meta-analysis
#13
REVIEW
Jonah Musa, Chad J Achenbach, Linda C O'Dwyer, Charlesnika T Evans, Megan McHugh, Lifang Hou, Melissa A Simon, Robert L Murphy, Neil Jordan
BACKGROUND: Although cervical cancer is largely preventable through screening, detection and treatment of precancerous abnormalities, it remains one of the top causes of cancer-related morbidity and mortality globally. OBJECTIVES: The objective of this systematic review is to understand the evidence of the effect of cervical cancer education compared to control conditions on cervical cancer screening rates in eligible women population at risk of cervical cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28860942/accuracy-of-cervical-cytology-comparison-of-diagnoses-of-100-pap-smears-read-by-four-pathologists-at-three-hospitals-in-norway
#14
Sveinung Wergeland Sørbye, Pål Suhrke, Berit Wallem Revå, Jannicke Berland, Ramona Johansen Maurseth, Khalid Al-Shibli
BACKGROUND: Cervical cancer can be prevented by early detection and treatment for precancerous lesions. Since 1995, there has been a national cervical cancer screening program in Norway, where women aged 25-69 years are recommended to take Pap smears every three years. There are 17 cytology laboratories covering a population of 5 million people. The detection rate of cervical abnormalities varies from laboratory to laboratory. We wanted to investigate the accuracy of cytology diagnoses by four different pathologists at three different hospitals in Norway...
2017: BMC Clinical Pathology
https://www.readbyqxmd.com/read/28843222/accuracy-of-cervical-visual-inspection-with-acetic-acid-guide-for-4-quadrant-random-cervical-biopsies-by-general-practitioners-in-women-with-abnormal-pap-smears
#15
Patrada Suwansura, Darigar Darojn
Objective: To study the performance of visual inspection with acetic acid plus 4-quadrant cervical biopsy (V4B) by general practitioners in detecting high grade cervical lesion, compared to highest histopathologic grade from the American Society for Colposcopy and Cervical Pathology American Society for Colposcopy and Cervical Pathology (ASCCP) 2013 work up guidelines. Materials and methods: Patients with abnormal cervical cytologic screening results suggesting low grade lesions underwent V4B by general practitioners followed by colposcopy on the same day bases on ASCCP 2013 guidelines...
August 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28832899/declining-prevalence-of-cytological-squamous-intraepithelial-lesions-of-the-cervix-among-women-living-with-well-controlled-hiv-most-women-living-with-hiv-do-not-need-annual-pap-smear-screening
#16
Inka Aho, Pia Kivelä, Jari Haukka, Jussi Sutinen, Oskari Heikinheimo
INTRODUCTION: Cervical screening by means of annual Papanicolaou (PAP) smears has been recommended for all women living with HIV. We analysed the results of our annual PAP smear screening program to identify low-risk subgroups for less rigorous screening. MATERIAL AND METHODS: The study comprised 369 women followed at the Helsinki University Hospital 2002-2013, with a total of 2033 PAP smear results. We analyzed the temporal changes in PAP smear findings. Logistic regression analysis for binominal dependent variables was used for assessing risk factors for ever having cytological squamous intraepithelial lesions (hereafter referred as SIL) using generalized estimating equations taking into account multiple observations of each patient...
November 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28821196/negative-predictive-value-and-significance-of-benign-appearing-endometrial-cells-in-papanicolaou-tests
#17
Jing Yu, Agnieszka Onisko, R Marshall Austin
Objectives: Reporting benign-appearing endometrial cells (nEMCs) in Papanicolaou (Pap) smears of women 40 years and older, introduced in The Bethesda System 2001, may be interpreted as an abnormal finding and lead to unnecessary endometrial biopsies. To our knowledge, this is the first study on the negative predictive value (NPV) of this cytology finding. Methods: An 11-year database with 1,036,629 Pap test reports and 121,079 surgical pathology reports identified reports of nEMCs in women 40 years and older with follow-up endometrial histopathology within 6 months...
September 1, 2017: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28770002/six-years-genotype-distribution-of-human-papillomavirus-in-calabria-region-southern-italy-a-retrospective-study
#18
Luisa Galati, Cinzia Peronace, Maria Teresa Fiorillo, Rosanna Masciari, Cristina Giraldi, Salvatore Nisticò, Pasquale Minchella, Vincenzo Maiolo, Giorgio Settimo Barreca, Nadia Marascio, Angelo Giuseppe Lamberti, Aida Giancotti, Maria Gabriella Lepore, Francesca Greco, Maria Vittoria Mauro, Annelisa Borelli, Giuseppa Lo Bocchiaro, Giovanni Surace, Maria Carla Liberto, Alfredo Focà
BACKGROUND: Although analysis of the Human papillomavirus (HPV) genotype spread in a particular area has a crucial impact on public health and prevention programmes, there is a lack of epidemiological data regarding HPV in the Calabria region of Italy. We therefore update information on HPV age/genotype distribution by retrospectively analysing a cohort of women, with and without cervical lesions, living in Calabria, who underwent HPV DNA testing; moreover, we also evaluated HPV age/genotype distribution in a subset of patients with cervical lesions...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28761025/eleven-year-review-of-data-on-pap-smears-in-saudi-arabia-we-need-more-focus-on-glandular-abnormalities
#19
Haitham Nasser, Mohammad AlAyyaf, Azza Atallah, Mohammad Aminulislam, Lubna Rizwan, Abdulsalam Aodah, Yasser Alkahtani, Haifa Alshammari, Ahmed Alsayed, Susan Szpunar
BACKGROUND: We reviewed data from Saudi Arabia on epithelial cell abnormalities (ECA) detected by Pap smear after noticing a slight increase in the incidence of cervical glandular abnormalities in our regional laboratory in recent years. OBJECTIVE: Clarify data on adenocarcinoma (ADCA) on Pap smears in Saudi Arabia. DESIGN: Descriptive, retrospective study. SETTINGS: Regional laboratory, Riyadh. PATIENTS AND METHODS: We reviewed all Pap smears of adult females between 2006 and 2016 and compared our data with previously published results from Saudi Arabia...
July 2017: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/28738387/false-negative-rate-of-papanicolaou-testing-a-national-survey-from-the-thai-society-of-cytology
#20
Supinda Koonmee, Andrey Bychkov, Somruetai Shuangshoti, Kanyaprin Bhummichitra, Wanwisa Himakhun, Anant Karalak, Samreung Rangdaeng
OBJECTIVE: To evaluate the performance of Papanicolaou smear screening in Thailand at the national level, and to propose recommendations for continuing quality control. STUDY DESIGN: This study was conducted by The Thai Society of Cytology and involved 124 laboratories in 76 provinces during 2010-2014. Random sampling suggested recalling of 10% of slides defined as negative at routine screenings (10% random rescreening [R10] model) directly from the reading unit...
July 25, 2017: Acta Cytologica
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