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https://www.readbyqxmd.com/read/29777323/andriod-device-based-cervical-cancer-screening-for-resource-poor-settings
#1
Vidya Kudva, Keerthana Prasad, Shyamala Guruvare
Visual inspection with acetic acid (VIA) is an effective, affordable and simple test for cervical cancer screening in resource-poor settings. But considerable expertise is needed to differentiate cancerous lesions from normal lesions, which is lacking in developing countries. Many studies have attempted automation of cervical cancer detection from cervix images acquired during the VIA process. These studies used images acquired through colposcopy or cervicography. However, colposcopy is expensive and hence is not feasible as a screening tool in resource-poor settings...
May 18, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29764329/preliminary-results-of-the-first-cervical-cancer-screening-programme-in-the-north-eastern-region-of-romania
#2
Ioana Păvăleanu, Dumitru Gafiţanu, Nicolae Ioanid, Mihaela Grigore
Objective Cervical cancer represents a major health problem in Romania. A national population-based cervical cancer screening programme was launched in 2012. The aims of the study were to assess the participation rate and to estimate the prevalence of epithelial cell abnormalities in the first four years of the programme in North Eastern Romania. Methods The participation rate, representing the proportion of eligible women screened in the programme, was evaluated for 2012-2016. The prevalence of cytological abnormalities was estimated by age group and calendar year...
January 1, 2018: Journal of Medical Screening
https://www.readbyqxmd.com/read/29727786/the-association-between-cervical-inflammation-and-histologic-evidence-of-hpv-in-pap-smears-and-adverse-pregnancy-outcome-in-low-risk-population
#3
Maya Nimrodi, Vered Kleitman, Tamar Wainstock, Ofer Gemer, Michai Meirovitz, Eli Maymon, Neta Benshalom-Tirosh, Offer Erez
OBJECTIVE: Recent studies suggest an association between Human Papilloma Virus (HPV) infection, cervical inflammation and obstetric complications (i.e. spontaneous preterm parturition and cervical insufficiency). It has been proposed that viral inflammation of the placenta causes changes in the mother's immune reaction to bacterial pathogens, which leads to enhanced inflammatory reaction and preterm delivery. Therefore, the aim of this population-based study was to determine the association between abnormal cervical cytology prior to pregnancy and obstetric outcomes...
April 20, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29722549/effects-of-equol-supplement-on-bone-and-cardiovascular-parameters-in-middle-aged-japanese-women-a-prospective-observational-study
#4
Remi Yoshikata, Khin Zay Yar Myint, Hiroaki Ohta
OBJECTIVE: To examine changes in the bone and cardiovascular parameters and tolerability in middle-aged Japanese women taking equol supplement for a year. DESIGN: This was a prospective observational study. SUBJECTS AND SETTING: Participants were 74 women receiving outpatient care at Hamasite Medical Clinic, Minato-ku, Tokyo, from 2013 to 2015. INTERVENTIONS: Participants received per oral equol-containing supplement, 10 mg/day...
May 3, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29722175/lack-of-transformation-zone-in-cervical-pap-tests-should-it-be-a-concern-a-quality-assurance-initiative
#5
Evelyn Carolina Polanco Jacome, Jennifer Maerki, Karen Chau, Meredith Akerman, Sujata Sajjan, Melissa Klein, Cecilia Gimenez, Alice Laser, Kasturi Das
BACKGROUND: Bethesda guidelines do not require presence of transformation zone (TZ) for a cervical Pap test to be deemed adequate. However, clinicians are concerned with specimens that are reported to lack TZ. METHODS: We analyzed 566 ThinPrep cases reported as negative for intraepithelial lesion or malignancy (NILM) with no cervical abnormality detected in previous 4 years (2007-2011). These cases were divided into two cohorts; those with TZ (ETZ) and those without TZ (NTZ)...
May 2, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29708835/the-effect-of-history-of-abnormal-pap-smear-or-preceding-hpv-infection-on-the-humoral-immune-response-to-quadrivalent-human-papilloma-virus-qhpv-vaccine-in-women-with-systemic-lupus-erythematosus
#6
J Patricia Dhar, Lynnette Essenmacher, Renee Dhar, Ardella Magee, Joel Ager, Robert J Sokol
OBJECTIVE: To determine if natural human papillomavirus (HPV) infection would induce an anamnestic response to quadrivalent (qHPV) vaccine in women with Systemic Lupus Erythematosus (SLE). METHODS: Thirty four women (19-50 years) with mild to moderate and minimally active or inactive SLE received standard qHPV vaccine. Neutralizing antibody titers to HPV 6, 11, 16 and18 were evaluated pre- and post- vaccine using HPV competitive Luminex Immunoassay. For each HPV type, logistic regressions were performed to explore the relationship between a positive titer at baseline with their final geometric mean titer and with the rise in titer...
April 30, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29672447/effects-of-human-papillomavirus-awareness-and-knowledge-on-psychological-state-of-women-referred-to-cervical-cancer-screening
#7
Ljiljana Markovic-Denic, Olivera Djuric, Natasa Maksimovic, Svetlana Popovac, Vesna Kesic
OBJECTIVE: The aim of the study was to assess the impact of human papillomavirus (HPV) awareness and knowledge on physiological state and quality of life of women referred to colposcopy and/or HPV testing. MATERIALS AND METHODS: A cross-sectional study was carried out at University Hospital, Belgrade, Serbia. The women with abnormal Pap test results obtained at the primary care centers requiring colposcopy and/or HPV testing were included. Before gynecological examination, participants filled the questionnaire on demographic characteristics, gynecological history, questionnaire for the evaluation of HPV awareness and HPV knowledge level, a set of self-report questionnaires assessing the anxiety level, quality of life, and concern about the smear and colposcopy results and perceived risk of developing cervical cancer...
April 19, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29663734/new-biological-research-and-understanding-of-papanicolaou-s-test
#8
REVIEW
Elizabeth R Smith, Sophia H George, Erin Kobetz, Xiang-Xi Xu
The development of the Papanicolaou smear test by Dr. George Nicholas Papanicolaou (1883-1962) is one of the most significant achievements in screening for disease and cancer prevention in history. The Papanicolaou smear has been used for screening of cervical cancer since the 1950s. The test is technically straightforward and practical and based on a simple scientific observation: malignant cells have an aberrant nuclear morphology that can be distinguished from benign cells. Here, we review the scientific understanding that has been achieved and continues to be made on the causes and consequences of abnormal nuclear morphology, the basis of Dr...
April 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29643651/pilot-study-of-an-open-source-image-analysis-software-for-automated-screening-of-conventional-cervical-smears
#9
Parikshit Sanyal, Prosenjit Ganguli, Sanghita Barui, Prabal Deb
Introduction: The Pap stained cervical smear is a screening tool for cervical cancer. Commercial systems are used for automated screening of liquid based cervical smears. However, there is no image analysis software used for conventional cervical smears. The aim of this study was to develop and test the diagnostic accuracy of a software for analysis of conventional smears. Materials and Methods: The software was developed using Python programming language and open source libraries...
April 2018: Journal of Cytology
https://www.readbyqxmd.com/read/29617952/risk-factors-for-human-papillomavirus-infection-and-abnormal-cervical-cytology-among-perinatally-human-immunodeficiency-virus-infected-and-uninfected-asian-youth
#10
Annette H Sohn, Stephen J Kerr, Rawiwan Hansudewechakul, Sivaporn Gatechompol, Kulkanya Chokephaibulkit, Hanh Le Dung Dang, Dan Ngoc Hanh Tran, Jullapong Achalapong, Nipat Teeratakulpisarn, Amphan Chalermchockcharoenkit, Manopchai Thamkhantho, Tippawan Pankam, Thida Singtoroj, Wichai Termrungruanglert, Surasith Chaithongwongwatthana, Nittaya Phanuphak
Background: Infection with high-risk human papillomavirus (HR-HPV) may be higher in perinatally human immunodeficiency virus (HIV)-infected (PHIV) than HIV-uninfected (HU) adolescents because of long-standing immune deficiency. Methods: PHIV and HU females aged 12-24 years in Thailand and Vietnam were matched by age group and lifetime sexual partners. At enrollment, blood, cervical, vaginal, anal, and oral samples were obtained for HPV-related testing. The Wilcoxon and Fisher exact tests were used for univariate and logistic regression for multivariate analyses...
March 30, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29571035/prevalence-and-age-wise-distribution-of-human-papillomavirus-type-16-18-infections-among-hospital-screened-women-of-a-peri-urban-area-in-west-bengal-impact-of-socio-demographic-factors
#11
Amrapali Bhattacharya, Shrinka Sen, Paramita Mandal, Sweta Sharma Saha, Somosree Sarkar, Om Prakash Pathak, Lena Biswas, Jayeeta Roy, Rimpa Banerjee, Ranita Roy Chowdhury, Manidip Pal, Ankur Mukherjee, Sharmila Sengupta
BACKGROUND: We undertook the current study on cervical Human Papillomavirus (HPV) prevalence along with cytology in women visiting the Gynecology Out-patient Department of a hospital for common gynecological ailments, subsequent to our earlier population-based study on HPV prevalence from India. METHODS: We analyzed data on cervical-cytology (Pap smears) and PCR-based molecular detection of HPV infection along with socio-demographic variables (N = 696). RESULTS: We identified 36...
March 20, 2018: Cancer Epidemiology
https://www.readbyqxmd.com/read/29527550/the-value-of-visual-inspection-with-acetic-acid-and-pap-smear-in-cervical-cancer-screening-program-in-low-resource-settings-a-population-based-study
#12
REVIEW
Nguyen Vu Quoc Huy, Le Minh Tam, Ngo Viet Quynh Tram, Dang Cong Thuan, Truong Quang Vinh, Cao Ngoc Thanh, Linus Chuang
This study aims to determine the diagnostic values of visual inspection with acetic acid (VIA) and Pap smear in a cervical cancer screening program at a community level in Vietnam. A cross-sectional analysis was obtained, including 1034 women of reproductive age from Thua Thien Hue Province, Vietnam from 09/2012 to 09/2013. Samples were taken from cervixes for Pap smear testing, followed by visual inspection with acetic acid. Subjects with abnormal VIA and/or positive cytology results were invited for colposcopy and biopsy...
May 2018: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29512809/the-prevelance-of-human-papillomavirus-hpv-genotypes-detected-by-pcr-in-women-with-normal-and-abnormal-cervico-vaginal-cytology
#13
Fatma Beyazit, Fatma Sılan, Meryem Gencer, Buket Aydin, Barış Paksoy, Mesut A Unsal, Ozturk Ozdemir
OBJECTIVES: Cervical cancer is the second most common type of cancer for women worldwide with a great proportion proved to be related to human papillomavirus (HPV) infection. As infection with HPV is the strongest risk factor for cervical neoplasia, detection of HPV genotypes in cervical and vaginal specimens of women with normal and abnormal cytology seems to be of paramount importance in cervical cancer screening. The objective of the study is to evaluate the prevalence and HPV genotypes among women with normal or abnormal Pap smear tests...
2018: Ginekologia Polska
https://www.readbyqxmd.com/read/29440214/-it-has-saved-thousands-of-lives-so-why-change-it-content-analysis-of-objections-to-cervical-screening-programme-changes-in-australia
#14
Helena M Obermair, Rachael H Dodd, Carissa Bonner, Jesse Jansen, Kirsten McCaffery
OBJECTIVES: The incidence and mortality of cervical cancer have halved since introduction of the Australian cervical screening programme in 1991, involving 2-yearly Pap smears from ages 18-69 years. In 2017, the programme changed to 5- yearly primary human papillomavirus (HPV) testing for women aged 25-74 years. This study investigated reasons for opposition to the renewed screening programme within the open-ended comments of an online petition, 'Stop May 1st Changes to Pap Smears-Save Women's Lives', opposing the changes, which received over 70 000 signatures and almost 20 000 comments...
February 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29416214/prevalence-of-specific-types-of-human-papiloma-virus-in-cervical-intraepithelial-lesions-and-cervical-cancer-in-macedonian-women
#15
Irena Aleksioska-Papestiev, Vesna Chibisheva, Megi Micevska, Goran Dimitrov
Introduction: Cervical cancer is a malignancy originating in the transformation zone of the cervix, most commonly in the squamous cells. It is the fourth most common cancer in women worldwide, and the third most common cause of female cancer death. Genital human papilloma viruses (HPV) are sexually transmitted and approximately 630 milion people worldwide are infected. More than 200 genotypes, subtypes and variants have been reported, 13-15 being oncogenic type, which could be responsible for cervical intraepithelial lesions (CIN) or cancer...
February 2018: Medical Archives
https://www.readbyqxmd.com/read/29406336/swedish-women-s-awareness-of-human-papillomavirus-and-health-related-quality-of-life-anxiety-and-depression-after-a-notification-of-an-abnormal-pap-smear-result-a-cross-sectional-study
#16
Marie Rask, Katarina Swahnberg, Marie Oscarsson
This study aims to assess (a) women's awareness of the human papillomavirus (HPV), (b) women's health-related quality of life (HRQoL) and levels of anxiety and depression symptoms, and (c) to compare the outcomes between women who are aware of the sexually transmitted nature of the HPV infection and women who are not. Swedish women who have been notified of an abnormal Pap smear result completed a questionnaire. This questionnaire consisted of sociodemographic characteristics, items on awareness of HPV, and how to cope with the Pap smear result and the instruments: the Functional Assessment of Chronic Illness Therapy - Cervical Dysplasia and the Hospital Anxiety and Depression Scale (HADS)...
February 5, 2018: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/29390909/colpocytological-abnormalities-in-hiv-infected-and-uninfected-pregnant-women-prevalence-persistence-and-progression
#17
Carmine Carriero, Fabiana Divina Fascilla, Paola Cramarossa, Achiropita Lepera, Stefano Bettocchi, Antonella Vimercati
In this retrospective case-control study, we analyse data of 48 HIV-positive pregnant patients, versus a control group of 99 HIV-negative pregnant women, followed as outpatients by our department from 2009 to 2014. The aims of the study were to investigate the prevalence, persistence and progression of cervical squamous intraepithelial lesions (SIL) in each group and to correlate colpo-cytological lesions to the socio-demographic and clinical-laboratory findings in the HIV + pregnant women. In our study we observed that immunosuppression, HPV infection and vaginal coinfections were predictive of cervical lesions...
February 1, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29374678/multiple-types-of-human-papillomavirus-infection-and-anal-precancerous-lesions-in-hiv-infected-men-in-taiwan-a-cross-sectional-study
#18
Shu-Hsing Cheng, Kuo-Sheng Liao, Chi-Chao Wang, Chien-Yu Cheng, Fang-Yeh Chu
OBJECTIVES: This study aimed to assess the relationship between infection with multiple human papillomavirus (HPV) types and abnormal anal cytology in HIV-infected men. DESIGN: An observational, cross-sectional study. SETTING: A regional referral hospital in Taiwan. PARTICIPANTS: In total, 714 HIV-infected men were enrolled between March 2011 and June 2016. Thin preparation anal Pap smears were interpreted according to the 2001 Bethesda System...
January 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29344435/synchronous-uterine-metastases-from-breast-cancer-case-study-and-literature-review
#19
REVIEW
Aisha Akhtar, Atul Ratra, Yana Puckett, Abu Baker Sheikh, Catherine A Ronaghan
Breast cancer rarely metastasizes to the uterus. Here, we report two breast cancer patients with synchronous metastases to the uterus. Case 1 highlights a 46-year-old female with invasive ductal carcinoma who presented with a breast mass and was found to have uterine enlargement on positron emission tomography (PET) scan. Biopsy revealed a metastatic 4 mm focus of breast cancer in the background of endometrial hyperplasia. Case 2 reports a 62-year-old postmenopausal female diagnosed with lobular carcinoma of the breast following an abnormal screening mammogram...
November 13, 2017: Curēus
https://www.readbyqxmd.com/read/29334204/detection-of-chlamydia-trachomatis-in-pap-smear-samples-from-south-khorasan-province-of-iran
#20
Davod Javanmard, Mahmoodreza Behravan, Malaknaz Ghannadkafi, Alireza Salehabadi, Masood Ziaee, Mohammad Hasan Namaei
Background: Chlamydia trachomatis (CT), the most common bacterial sexually transmitted infection (STI), leads to pelvic inflammatory disease, infertility and chronic pelvic pain in women as well as an increased risk of vertical transmission, conjunctivitis and pneumonitis in infants. It may also be a co-factor along with human papillomavirus (HPV) in cervical cancer progression. We aimed to determine the prevalence of CT genotypes in genital specimens of women from South Khorasan, Iran and to test the association between CT and cytology statistics...
April 2018: International Journal of Fertility & Sterility
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