Read by QxMD icon Read


Dong Qian, Bei Wang, Yun Qing, Tao Zhang, Yu Zhang, Xing Wang, Masatoshi Nakamura
Daytime short nap involves physiological processes, such as alertness, drowsiness and sleep. The study of the relationship between drowsiness and nap based on physiological signals is a great way to have a better understanding of the periodical rhymes of physiological states. A model of Bayesian nonnegative CP decomposition (BNCPD) was proposed to extract common multiway features from the group-level electroencephalogram (EEG) signals. As an extension of the nonnegative CP decomposition, the BNCPD model involves prior distributions of factor matrices, while the underlying CP rank could be determined automatically based on a Bayesian nonparametric approach...
October 19, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
Brice Faraut, Thomas Andrillon, Marie-Françoise Vecchierini, Damien Leger
Sleep specialists have proposed measures to counteract the negative short- and long-term consequences of sleep debt, and some have suggested the nap as a potential and powerful "public health tool". Here, we address this countermeasure aspect of napping viewed as an action against sleep deprivation rather than an action associated with poor health. We review the physiological functions that have been associated positively with napping in both public health and clinical settings (sleep-related accidents, work and school, and cardiovascular risk) and in laboratory-based studies with potential public health issues (cognitive performance, stress, immune function and pain sensitivity)...
September 13, 2016: Sleep Medicine Reviews
Andreas Beyer, Holger Grohganz, Korbinian Löbmann, Thomas Rades, Claudia S Leopold
Co-amorphisation represents a promising approach to increase the physical stability and dissolution rate of amorphous active pharmaceutical ingredients (APIs) as an alternative to polymer glass solutions. For amorphous and co-amorphous systems, it is reported that the preparation method and the blend ratio play major roles with regard to the resulting physical stability. Therefore, in the present study, co-amorphous naproxen-indomethacin (NAP/IND) was prepared by melt-quenching at three different cooling rates and at ten different NAP/IND blend ratios...
October 13, 2016: European Journal of Pharmaceutics and Biopharmaceutics
Anne Marie Greenhalgh, Leticia Gonzalez-Blanco, Clemente Garcia-Rizo, Emilio Fernandez-Egea, Brian Miller, Miguel Bernardo Arroyo, Brian Kirkpatrick
BACKGROUND: Some studies have suggested that antipsychotic-naïve patients with nonaffective psychosis (NAP) have glucose intolerance. AIMS: To conduct a systematic review and meta-analysis of fasting glucose (FG), two hour values in the oral glucose tolerance test (2HG), fasting insulin concentration (INS), and insulin resistance (IR). METHOD: We identified possibly relevant studies, then selected studies, following usual guidelines, with two authors reviewing the manuscripts...
October 13, 2016: Schizophrenia Research
Jing Zhou, Lu Ke, Dongliang Yang, Yizhe Chen, Gang Li, Zhihui Tong, Weiqin Li, Jieshou Li
BACKGROUND: Splanchnic venous thrombosis (SVT) is a relatively rare but important complication of necrotizing acute pancreatitis (NAP). Clinical manifestations and severity of this complication in different patients vary greatly, ranging from mild abdominal discomfort even asymptomatic to lethal gastrorrhagia or hepatic failure. The aim of the present study was to develop a model to predict the clinical manifestations of SVT in NAP patients. METHODS: This retrospective cohort study was conducted in the surgical intensive care unit (SICU) of Jinling Hospital...
October 3, 2016: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
Geneviève Albouy, Bradley R King, Christina Schmidt, Martin Desseilles, Thien Thanh Dang-Vu, Evelyne Balteau, Christophe Phillips, Christian Degueldre, Pierre Orban, Habib Benali, Philippe Peigneux, André Luxen, Avi Karni, Julien Doyon, Pierre Maquet, Maria Korman
Motor memory consolidation is characterized, in part, by a sleep-facilitated decrease in susceptibility to subsequent interfering experiences. Surprisingly, the cerebral substrates supporting this phenomenon have never been examined. We used fMRI to investigate the neural correlates of the influence of sleep on interference to motor memory consolidation. Healthy young adults were trained on a sequential motor task, and subsequently practiced a second competing sequence after an interval including diurnal sleep or wakefulness...
October 11, 2016: Scientific Reports
Shalini Paruthi, Lee J Brooks, Carolyn D'Ambrosio, Wendy A Hall, Suresh Kotagal, Robin M Lloyd, Beth A Malow, Kiran Maski, Cynthia Nichols, Stuart F Quan, Carol L Rosen, Matthew M Troester, Merrill S Wise
Members of the American Academy of Sleep Medicine developed consensus recommendations for the amount of sleep needed to promote optimal health in children and adolescents using a modified RAND Appropriateness Method. After review of 864 published articles, the following sleep durations are recommended: Infants 4 months to 12 months should sleep 12 to 16 hours per 24 hours (including naps) on a regular basis to promote optimal health. Children 1 to 2 years of age should sleep 11 to 14 hours per 24 hours (including naps) on a regular basis to promote optimal health...
September 29, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Kui Peng, Lin Lin, Zhengyi Wang, Lin Ding, Ya Huang, Po Wang, Yu Xu, Jieli Lu, Min Xu, Yufang Bi, Weiqing Wang, Yuhong Chen, Guang Ning
BACKGROUND: Epidemiologic studies have reported conflicting results on the relationship between short sleep duration and nonalcoholic fatty liver disease (NAFLD). Previous research investigating the impact of daytime nap on NAFLD was not available. Herein, we examined the associations between nightly sleep duration, daytime nap with NAFLD in a middle-aged and elderly Chinese population. METHODS: This cross-sectional community-based population study included 8559 individuals aged 40 years or older...
October 4, 2016: Journal of Diabetes
Ye Wen, Fu-Hua Pi, Pi Guo, Wen-Ya Dong, Yu-Qing Xie, Xiang-Yu Wang, Fang-Fang Xia, Shao-Jie Pang, Yan-Chun Wu, Yuan-Yuan Wang, Qing-Ying Zhang
Sleep habits are associated with stroke in western populations, but this relation has been rarely investigated in China. Moreover, the differences among stroke subtypes remain unclear. This study aimed to explore the associations of total stroke, including ischemic and hemorrhagic type, with sleep habits of a population in southern China. We performed a case-control study in patients admitted to the hospital with first stroke and community control subjects. A total of 333 patients (n = 223, 67.0%, with ischemic stroke; n = 110, 23...
October 4, 2016: Scientific Reports
Arne H Eliasson, Arn H Eliasson, Christopher J Lettieri
PURPOSE: To inform the design of a sleep improvement program for college students, we assessed academic performance, sleep habits, study hours, and extracurricular time, hypothesizing that there would be differences between US-born and foreign-born students. METHODS: Questionnaires queried participants on bedtimes, wake times, nap frequency, differences in weekday and weekend sleep habits, study hours, grade point average, time spent at paid employment, and other extracurricular activities...
September 30, 2016: Sleep & Breathing, Schlaf & Atmung
S B Liu, Y X Hu, X D Liao, L Lu, S F Li, L Y Zhang, H Z Tan, L Yang, H Q Suo, X G Luo
Two experiments were conducted using 22-d-old Arbor Acres male broilers to study the kinetics of inorganic P absorption and the effect of P treatment on Type IIb sodium-phosphate cotransporter (NaP-IIb) mRNA and protein levels in ligated segments from different intestinal regions. In Exp. 1, the P absorption in different small intestinal segments at different postperfusion times (0, 2.5, 5, 10, 20, or 40 min) were compared. In Exp. 2, different small intestinal loops were perfused with solutions containing 0, 1...
August 2016: Journal of Animal Science
Davide Carta, Nicola Salvarese, Nicolò Morellato, Feng Gao, Wiebke Sihver, Hans Jurgen Pietzsch, Barbara Biondi, Paolo Ruzza, Fiorenzo Refosco, Debora Carpanese, Antonio Rosato, Cristina Bolzati
The purpose of this study was to evaluate the effect of cyclization on the biological profile of a [(99m)Tc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analog. A lactam bridge-cyclized H-Cys-Ahx-βAla(3)-c[Lys(4)-Glu-His-D-Phe-Arg-Trp-Glu(10)]-Arg(11)-Pro-Val-NH2 (NAP-NS2) and the corresponding linear H-Cys-Ahx-βAla-Nle-Asp-His-D-Phe-Arg-Trp-Gly-NH2 (NAP-NS1) peptide were synthetized, characterized by ESI-MS spectroscopy and their melanocortin-1 receptor (MC1R) binding affinity was determined in B16/F10 melanoma cells...
August 31, 2016: Nuclear Medicine and Biology
Yue Leng, Nick W J Wainwright, Francesco P Cappuccio, Paul G Surtees, Shabina Hayat, Robert Luben, Carol Brayne, Kay-Tee Khaw
BACKGROUND: We have identified a strong association between daytime napping and increased mortality risk from respiratory diseases, but little is known about the relationship between daytime napping and respiratory morbidity. METHODS: Data were drawn from the European Prospective Investigation into Cancer and Nutrition-Norfolk cohort. Participants reported napping habits during 1998-2000 and were followed up for respiratory disease hospital admissions until March 2009...
July 2016: Sleep Medicine
David Looney, Valentin Goverdovsky, Ivana Rosenzweig, Mary J Morrell, Danilo P Mandic
RATIONALE: To date the only quantifiable measure of neural changes that define sleep is electroencephalography (EEG). Although widely used for clinical testing, scalp-electrode EEG is costly and poorly tolerated by sleeping patients. OBJECTIVES: This is a pilot study to assess the agreement between EEG recordings obtained from a new ear-EEG sensor and those obtained simultaneously from standard scalp electrodes. METHODS: Participants were 4 healthy men, ages 25 to 36 years...
September 29, 2016: Annals of the American Thoracic Society
Jyotilima Saikia, Puja Khare, Prasenjit Saikia, Binoy K Saikia
In the present investigation, the concentrations of polycyclic aromatic hydrocarbons (PAHs) associated with PM2.5, PM10 and dust particles emitted from two tea processing industrial units were studied that uses high-sulfur coal as their energy source. A total of 16 PAHs (viz. naphthalene (Nap), acenaphthene (Ace), acenaphthylene (Acen), phenanthrene (Phe), fluorene (Flu), anthracene (Ant), fluoranthene (Fluo), pyrene (Pyr), benz[a]anthracene (BaA), chrysene (Chry), benzo[b]fluoranthene (BbF), benzo[k]fluoranthene (BkF), benzo[a]pyrene (BaP), dibenz[a,h]anthracene (DBahA), indeno[1,2,3-cd]pyrene (IP) and benzo[ghi]perylene (BghiP) were measured...
September 27, 2016: Environmental Geochemistry and Health
Peng Bao, Ke-Qing Xiao, Hui-Jiao Wang, Hao Xu, Peng-Peng Xu, Yan Jia, Max M Häggblom, Yong-Guan Zhu
A novel nitrate- and selenite reducing bacterium strain ZYK(T) was isolated from a rice paddy soil in Dehong, Yunnan, China. Strain ZYK(T) is a facultative anaerobe and grows in up to 150, 000 ppm O2. The comparative genomics analysis of strain ZYK(T) implies that it shares more orthologues with B. subtilis subsp. subtilis NCIB 3610(T) (ANIm values, 85.4-86.7%) than with B. azotoformans NBRC 15712(T) (ANIm values, 84.4-84.7%), although B. azotoformans NBRC 15712(T) (96.3% 16S rRNA gene sequence similarity) is the closest Bacillus species according to 16S rRNA gene comparison...
September 28, 2016: Scientific Reports
Yeganeh Talebkhan, Mohsen Doozbakhshan, Samaneh Saberi, Maryam Esmaeili, Najmeh Karami, Nazanin Mohajerani, Afshin Abdirad, Mahmoud Eshagh Hosseini, Azin Nahvijou, Mohammad Ali Mohagheghi, Marjan Mohammadi
BACKGROUND: Gastric cancer arises, mainly, on an inflammatory background. Helicobacter pylori neutrophil activating (HP-NAP) protein functions as a potent pro-inflammatory mediator. Similarly, IL-4 plays a critical role in the inflammation pathway, the levels of which are altered by C to T transition at position -590 in its promoter region. Here, we have aimed to assess the risk of gastritis and gastric cancer in the co-presence of these two inflammation modulating mediators. METHODS: Gastritis (n=58) and gastric cancer (n=31) patients were evaluated and compared with H...
September 28, 2016: Iranian Biomedical Journal
Sara E Alger, Jessica D Payne
Relational memories are formed from shared components between directly learned memory associations, flexibly linking learned information to better inform future judgments. Sleep has been found to facilitate both direct associative and relational memories. However, the impact of incorporating emotionally salient information into learned material and the interaction of emotional salience and sleep in facilitating both types of memory is unknown. Participants encoded two sets of picture pairs, with either emotionally negative or neutral objects paired with neutral faces...
September 26, 2016: Cognitive, Affective & Behavioral Neuroscience
Qianhua Dong, Feng-Xiang Yin, Feng Gao, Yuan Shen, Faben Zhang, Yang Li, Haijin He, Marlyn Gonzalez, Jinpu Yang, Shu Zhang, Min Su, Yu-Hang Chen, Fei Li
CENP-A is a centromere-specific histone 3 variant essential for centromere specification. CENP-A partially replaces canonical histone H3 at the centromeres. How the particular CENP-A/H3 ratio at centromeres is precisely maintained is unknown. It also remains unclear how CENP-A is excluded from non-centromeric chromatin. Here, we identify Ccp1, an uncharacterized NAP family protein in fission yeast that antagonizes CENP-A loading at both centromeric and non-centromeric regions. Like the CENP-A loading factor HJURP, Ccp1 interacts with CENP-A and is recruited to centromeres at the end of mitosis in a Mis16-dependent manner...
October 6, 2016: Molecular Cell
Emily Urry, Alexander Jetter, Sebastian C Holst, Wolfgang Berger, Giatgen A Spinas, Wolfgang Langhans, Hans-Peter Landolt
OBJECTIVES: The purpose of this study was to examine the possible links between type 2 diabetes, daytime sleepiness, sleep quality and caffeine consumption. METHODS: In this case-control field study, comparing type 2 diabetic (n=134) and non-type 2 diabetic (n=230) participants, subjects completed detailed and validated questionnaires to assess demographic status, health, daytime sleepiness, sleep quality and timing, diurnal preference, mistimed circadian rhythms and habitual caffeine intake...
September 20, 2016: Journal of Psychopharmacology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"