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Human body anatomy

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https://www.readbyqxmd.com/read/28547783/aortic-arch-origin-of-the-left-vertebral-artery-an-anatomical-and-radiological-study-with-significance-for-avoiding-complications-with-anterior-approaches-to-the-cervical-spine
#1
Gabrielle G Tardieu, Bryan Edwards, Fernando Alonso, Koichi Watanabe, Tsuyoshi Saga, Moriyoshi Nakamura, Mayuko Motomura, Raghu Sampath, Joe Iwanaga, Oded Goren, Stephen Monteith, Rod J Oskouian, Marios Loukas, R Shane Tubbs
INTRODUCTION: Complications from anterior approaches to the cervical spine are uncommon with normal anatomy. However, variant anatomy might predispose one to an increased incidence of injury during such procedures. We hypothesized that left vertebral arteries that arise from the aortic arch instead of the subclavian artery might take a more medial path in their ascent making them more susceptible to iatrogenic injury. MATERIALS AND METHODS: Fifty human adult cadavers were examined for left vertebral arteries having an aortic arch origin and these were dissected along their entire cervical course...
May 25, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28541191/fast-numerical-simulation-of-focused-ultrasound-treatments-during-respiratory-motion-with-discontinuous-motion-boundaries
#2
Michael Schwenke, Joachim Georgii, Tobias Preusser
OBJECTIVE: Focused ultrasound (FUS) is rapidly gaining clinical acceptance for several target tissues in the human body. Yet, treating liver targets is not clinically applied due to a high complexity of the procedure (noninvasiveness, target motion, complex anatomy, blood cooling effects, shielding by ribs, and limited image-based monitoring). To reduce the complexity, numerical FUS simulations can be utilized for both treatment planning and execution. These use-cases demand highly accurate and computationally efficient simulations...
May 23, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28538555/the-anatomy-of-the-facial-vein-implications-for-plastic-reconstructive-and-aesthetic-procedures
#3
Sebastian Cotofana, Hanno Steinke, Alexander Schlattau, Markus Schlager, Jonathan M Sykes, Malcolm Z Roth, Alexander Gaggl, Riccardo E Giunta, Robert H Gotkin, Thilo L Schenck
BACKGROUND: Anatomical knowledge of the facial vasculature is crucial for successful plastic, reconstructive, and minimally invasive procedures of the face. Whereas the majority of previous investigations focused on facial arteries, the precise course, variability, and relationship with adjacent structures of the facial vein have been widely neglected. METHODS: Seventy-two fresh frozen human cephalic cadavers (32 male and 40 female cadavers; mean age, 75.2 ± 10...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28535851/dancers-perceived-and-actual-knowledge-of-anatomy
#4
Dana H Kotler, Meaghan Lynch, Daniel Cushman, Jason Hu, Jocelyn Garner
Dancers are highly susceptible to musculoskeletal injuries and frequently require interaction with medical professionals. While many dancers have a finely tuned awareness of their bodies, their knowledge of the fundamentals of human anatomy is not uniform. There is a paucity of literature on the benefits of human anatomy education in dancers, though it seems intuitive that there should be a relationship. The purpose of this study was to assess dancers' perceived and actual knowledge of basic musculoskeletal anatomy and its relationship to function...
June 15, 2017: Journal of Dance Medicine & Science
https://www.readbyqxmd.com/read/28527481/rethinking-anatomy-how-to-overcome-challenges-of-medical-education-s-evolution
#5
REVIEW
Bruno Guimarães, Luís Dourado, Stanislav Tsisar, José Miguel Diniz, Maria Dulce Madeira, Maria Amélia Ferreira
INTRODUCTION: Due to scientific and technological development, Medical Education has been readjusting its focus and strategies. Medical curriculum has been adopting a vertical integration model, in which basic and clinical sciences coexist during medical instruction. This context favours the introduction of new complementary technology-based pedagogical approaches. Thus, even traditional core sciences of medical curriculum, like Anatomy, are refocusing their teaching/learning paradigm...
February 27, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28504201/cilia-the-sensory-antennae-in-the-eye
#6
REVIEW
Helen May-Simera, Kerstin Nagel-Wolfrum, Uwe Wolfrum
Cilia are hair-like projections found on almost all cells in the human body. Originally believed to function merely in motility, the function of solitary non-motile (primary) cilia was long overlooked. Recent research has demonstrated that primary cilia function as signalling hubs that sense environmental cues and are pivotal for organ development and function, tissue hoemoestasis, and maintenance of human health. Cilia share a common anatomy and their diverse functional features are achieved by evolutionarily conserved functional modules, organized into sub-compartments...
May 11, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28500091/forensic-age-estimation-using-the-medial-clavicular-epiphysis-a-study-review
#7
Mary B Buckley, Kevin R Clark
PURPOSE: To discuss current literature evaluating the medial clavicular epiphysis to assess an individual's age using various imaging modalities. METHODS: Four scholarly research databases were searched to find studies that examined living subjects. Several articles were included that used cadavers, and a textbook was used to detail the anatomy of the clavicle. Thirty-nine articles were analyzed. RESULTS: The literature indicated that several imaging modalities, including conventional radiography, computed tomography, magnetic resonance, and sonography, are being used to evaluate the medial clavicular epiphysis to estimate an individual's age in the forensic context...
May 2017: Radiologic Technology
https://www.readbyqxmd.com/read/28484627/the-chinchilla-as-a-novel-animal-model-of-pregnancy
#8
Emmeli Mikkelsen, Henrik Lauridsen, Per Mose Nielsen, Haiyun Qi, Thomas Nørlinger, Maria Dahl Andersen, Niels Uldbjerg, Christoffer Laustsen, Puk Sandager, Michael Pedersen
Several parameters are important when choosing the most appropriate animal to model human obstetrics, including gestation period, number of fetuses per gestation and placental structure. The domesticated long-tailed chinchilla (Chinchilla lanigera) is a well-suited and appropriate animal model of pregnancy that often will carry only one offspring and has a long gestation period of 105-115 days. Furthermore, the chinchilla placenta is of the haemomonochorial labyrinthine type and is therefore comparable to the human villous haemomonochorial placenta...
April 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28466514/challenges-in-identifying-and-interpreting-organizational-modules-in-morphology
#9
Borja Esteve-Altava
Form is a rich concept that agglutinates information about the proportions and topological arrangement of body parts. Modularity is readily measurable in both features, the variation of proportions (variational modules) and the organization of topology (organizational modules). The study of variational modularity and of organizational modularity faces similar challenges regarding the identification of meaningful modules and the validation of generative processes; however, most studies in morphology focus solely on variational modularity, while organizational modularity is much less understood...
May 2, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28444223/gene-organizer-linking-genes-to-the-organs-they-affect
#10
David Gokhman, Guy Kelman, Adir Amartely, Guy Gershon, Shira Tsur, Liran Carmel
One of the biggest challenges in studying how genes work is understanding their effect on the physiology and anatomy of the body. Existing tools try to address this using indirect features, such as expression levels and biochemical pathways. Here, we present Gene ORGANizer (geneorganizer.huji.ac.il), a phenotype-based tool that directly links human genes to the body parts they affect. It is built upon an exhaustive curated database that links >7000 genes to ∼150 anatomical parts using >150 000 gene-organ associations...
April 21, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28413859/meniscus-articular-cartilage-and-nucleus-pulposus-a-comparative-review-of-cartilage-like-tissues-in-anatomy-development-and-function
#11
REVIEW
Song Chen, Peiliang Fu, Haishan Wu, Ming Pei
The degradation of cartilage in the human body is impacted by aging, disease, genetic predisposition and continued insults resulting from daily activity. The burden of cartilage defects (osteoarthritis, rheumatoid arthritis, intervertebral disc damage, knee replacement surgeries, etc.) is daunting in light of substantial economic and social stresses. This review strives to broaden the scope of regenerative medicine and tissue engineering approaches used for cartilage repair by comparing and contrasting the anatomical and functional nature of the meniscus, articular cartilage (AC) and nucleus pulposus (NP)...
April 17, 2017: Cell and Tissue Research
https://www.readbyqxmd.com/read/28400207/the-safety-and-efficacy-of-growth-hormone-secretagogues
#12
REVIEW
John T Sigalos, Alexander W Pastuszak
INTRODUCTION: Growth hormone (GH) increases lean body mass, decreases fat mass, increases exercise tolerance and maximum oxygen uptake, enhances muscle strength, and improves linear growth. Long-term studies of GH administration offer conflicting results on its safety, which has led to strict Food and Drug Administration criteria for GH use. The potential drawbacks of exogenous GH use are believed to be due in part to impaired regulatory feedback. AIM: To review the literature on GH secretagogues (GHSs), which include GH-releasing peptides and the orally available small-molecule drug ibutamoren mesylate...
April 8, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28377682/body-of-evidence-integrating-eduard-pernkopf-s-atlas-into-a-librarian-led-medical-humanities-seminar
#13
Keith C Mages, Linda A Lohr
BACKGROUND: Anatomical subjects depicted in Eduard Pernkopf's richly illustrated Topographische Anatomie des Menschen may be victims of the Nazi regime. Special collections librarians in the history of medicine can use this primary resource to initiate dialogs about ethics with medical students. CASE PRESENTATION: Reported here is the authors' use of Pernkopf's Atlas in an interactive medical humanities seminar designed for third-year medical students. Topical articles, illustrations, and interviews introduced students to Pernkopf, his Atlas, and the surrounding controversies...
April 2017: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/28362409/intraductal-delivery-to-the-rabbit-mammary-gland
#14
Amelia Clark, Nora K Bird, Amy Brock
Localized intraductal treatments for breast cancer offer potential advantages, including efficient delivery to the tumor and reduced systemic toxicity and adverse effects(1)(,)(2)(,)(3)(,)(4)(,)(5)(,)(6)(,)(7). However, several challenges remain before these treatments can be applied more widely. The development and validation of intraductal therapeutics in an appropriate animal model facilitate the development of intraductal therapeutic strategies for patients. While the mouse mammary gland has been widely used as a model system of mammary development and tumorigenesis, the anatomy is distinct from the human gland...
March 9, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28340659/exploring-new-frontiers-of-microsurgery-from-anatomy-to-clinical-methods
#15
REVIEW
Zeng Tao Wang, You Mao Zheng, Lei Zhu, Li Wen Hao, Ya Bin Zhang, Chao Chen, Li Feng Xia, Lin Feng Liu
This article presents the authors' understanding and experience concerning anatomic studies and clinical methods in microsurgical hand reconstruction. The 4 parts of this article include anatomic study of the hand for developing new flaps; application of miniflaps from the hand, including clinical experience with 8 unique flaps in the hand; anatomic and clinical considerations concerning several flaps from other parts of the human body; And our experience with vascularized free toe joint transfer.
April 2017: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/28332867/age-related-changes-in-thoracic-skeletal-geometry-of-elderly-females
#16
Sven A Holcombe, Stewart C Wang, James B Grotberg
OBJECTIVE: Both females and the elderly have been identified as vulnerable populations with increased injury and mortality risk in multiple crash scenarios. Particularly in frontal impacts, older females show higher risk to the chest and thorax than their younger or male counterparts. Thoracic geometry plays a role in this increase, and this study aims to quantify key parts of that geometry in a way that can directly inform human body models that incorporate the concept of person age...
May 29, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28326490/virtual-reality-educational-tool-for-human-anatomy
#17
Santiago González Izard, Juan A Juanes Méndez, Pablo Ruisoto Palomera
Virtual Reality is becoming widespread in our society within very different areas, from industry to entertainment. It has many advantages in education as well, since it allows visualizing almost any object or going anywhere in a unique way. We will be focusing on medical education, and more specifically anatomy, where its use is especially interesting because it allows studying any structure of the human body by placing the user inside each one. By allowing virtual immersion in a body structure such as the interior of the cranium, stereoscopic vision goggles make these innovative teaching technologies a powerful tool for training in all areas of health sciences...
May 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28323442/an-investigation-of-human-body-model-morphing-for-the-assessment-of-abdomen-responses-to-impact-against-a-population-of-test-subjects
#18
Philippe Beillas, Fabien Berthet
OBJECTIVE: Human body models have the potential to better describe the human anatomy and variability than dummies. However, data sets available to verify the human response to impact are typically limited in numbers, and they are not size or gender specific. The objective of this study was to investigate the use of model morphing methodologies within that context. METHODS: In this study, a simple human model scaling methodology was developed to morph two detailed human models (Global Human Body Model Consortium models 50th male, M50, and 5th female, F05) to the dimensions of post mortem human surrogates (PMHS) used in published literature...
May 29, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28317555/the-cervical-spine-of-australopithecus-sediba
#19
Marc R Meyer, Scott A Williams, Peter Schmid, Steven E Churchill, Lee R Berger
Cervical vertebrae are rare in the early hominin fossil record, presenting a challenge for understanding the evolution of the neck and head carriage in hominin evolution. Here, we examine the cervical vertebrae of Australopithecus sediba, which unlike other South African taxa is known from associated cervical vertebrae. The A. sediba cervical vertebrae exhibit human-like values for wedging, pedicle cross-sectional areas, and articular facet heights, indicating reduced ventral loading relative to African apes...
March 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28299781/architectural-differences-in-the-anterior-and-middle-compartments-of-the-pelvic-floor-of-young-adult-and-postmenopausal-females
#20
Yi Wu, Noshir F Dabhoiwala, Jaco Hagoort, Li-Wen Tan, Shao-Xiang Zhang, Wouter H Lamers
The pelvic floor guards the passage of the pelvic organs to the exterior. The near-epidemic prevalence of incontinence in women continues to generate interest in the functional anatomy of the pelvic floor. However, due to its complex architecture and poor accessibility, the classical 'dissectional' approach has been unable to come up with a satisfactory description, so that many aspects of its anatomy continue to raise debate. For this reason, we opted for a 'sectional' approach, using the Chinese Visible Human project (four females, 21-35 years) and the Visible Human Project (USA; one female, 59 years) datasets to investigate age-related changes in the architecture of the anterior and middle compartments of the pelvic floor...
March 16, 2017: Journal of Anatomy
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