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https://www.readbyqxmd.com/read/28530132/development-of-a-high-fidelity-pressurized-porcine-beating-heart-simulator-for-cardiac-surgery-training
#1
Igo B Ribeiro, Janet M C Ngu, Gurinder Gill, Fraser D Rubens
BACKGROUND: Development of a high-fidelity cardiac surgery simulator (CSS) requires integration of a heart model with a mock cardiopulmonary bypass (CPB) circuit that can provide feedback to mimic the pathophysiology of cardiac surgery. However, the cost of commercially available simulators precludes regular use. We describe steps in the construction of a high-fidelity CSS that integrates a pulsatile paracorporeal ventricular-assist device (Pulse-VAD) and a commercially available CPB simulator...
May 1, 2017: Perfusion
https://www.readbyqxmd.com/read/28528718/double-outlet-right-ventricle-revisited
#2
Ameneh Ebadi, Diane E Spicer, Carl L Backer, F Jay Fricker, Robert H Anderson
OBJECTIVES: Double-outlet right ventricle is a form of ventriculoarterial connection. The definition formulated by the International Society for Nomenclature of Paediatric and Congenital Heart Disease is based on hearts with both arterial trunks supported in their greater part by a morphologically right ventricle. Bilateral infundibula and ventricular septal defects are highly debated criteria. This study examines the anatomic controversies surrounding double-outlet right ventricle. We show that hearts with double-outlet right ventricle can have atrioventricular-to-arterial valvular continuity...
March 23, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28526085/papillary-fibroelastoma-unusual-cause-of-stroke-in-a-young-man-a-case-report
#3
Elisabetta Grolla, Michele Dalla Vestra, Giampaolo Zoffoli, Riccardo D'Ascoli, Adriana Critelli, Rocco Quatrale, Domenico Mangino, Fausto Rigo
BACKGROUND: Papillary fibroelastoma is the third most common primary benign tumor with an incidence of up to 0.33% in autopsy series; it accounts for approximately 75% of all cardiac valvular tumors. CASE PRESENTATION: We describe a rare case of a 28-Year-old man that while playing football, had a sudden onset of neurological deficit: aphasia, right hemiparesis and right facial numbness. Transthoracic echocardiography (TTE) showed a 10x10 mm mass attached to the anterior mitral valve leaflet...
May 19, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28518178/physical-function-and-exercise-training-in-older-patients-with-heart-failure
#4
REVIEW
Andrew J Stewart Coats, Daniel E Forman, Mark Haykowsky, Dalane W Kitzman, Amy McNeil, Tavis S Campbell, Ross Arena
Heart failure (HF) is a common end point for numerous cardiovascular conditions, including coronary artery disease, valvular disease, and hypertension. HF predominantly affects older individuals (aged ≥70 years), particularly those living in developed countries. The pathophysiological sequelae of HF progression have a substantial negative effect on physical function. Diminished physical function in older patients with HF, which is the result of combined disease-related and age-related effects, has important implications on health...
May 18, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28507837/non-alcoholic-fatty-liver-disease-association-with-cardiac-arrhythmias
#5
REVIEW
Muhammad A Mangi, Hiba Rehman, Abdul M Minhas, Muhammad Rafique, Vikas Bansal, Jonathan Constantin
Non-alcoholic fatty liver disease (NAFLD) has become a public health burden all over the world. A significant percentage of the patients with NAFLD have a co-existing metabolic syndrome that is a risk factor for cardiovascular disease. Clinical as well as epidemiological research shows that NAFLD is not simply related to liver-related morbidity and mortality but is also associated with an elevated risk of coronary heart disease (CHD), irregularities of cardiac function as well as cardiac structure, valvular heart disease, and arrhythmias...
April 13, 2017: Curēus
https://www.readbyqxmd.com/read/28506547/transcatheter-mitral-valve-interventions-for-mitral-regurgitation-with-special-focus-on-mitraclip-the-position-of-spanish-portuguese-and-italian-interventional-societies
#6
Rodrigo Estévez-Loureiro, Xavier Freixa, Dabit Arzamendi, Armando Perez de Prado, Rui Campante-Teles, Bruno Melica, Giuseppe Tarantini, Giuseppe Musumeci, Manuel Pan
Mitral regurgitation is a common valvular heart disease and its prevalence is expected to increase with population ageing. In the recent years we have witnessed the evolution of several transcatheter devices to correct mitral regurgitation in patients at high-risk for surgery. Most of the evidence of the safety and efficacy of this new therapy comes from MitraClip studies. However, new alternatives have emerged with promising results. The aim of this position paper is to review the current evidence regarding patient selection, expected results and timing for transcatheter mitral valve interventions from the perspective of three European interventional societies...
May 9, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28504227/israel-coronary-and-structural-heart-interventions-from-2010-to-2015
#7
Ariel Finkelstein, Saar Minha, Ran Kornowski, Haim Danenberg, Shmuel Banai, Haim Lotan, Amit Segev, Israel M Barbash
The Israel Heart Society is a member of the European Society of Cardiology, and the Israeli Working Group of Interventional Cardiology is an active participant in EAPCI. The aim of this manuscript is to provide a snapshot of cardiac interventions performed in the State of Israel during the period 2010-2015. Data for this manuscript were collected via collaboration with the National Diseases Registries Unit of the Israel Center for Disease Control. During the survey period, the Israeli population increased by 7% but only one additional hospital with an active cardiac catheterisation laboratory was opened...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28501384/acute-heart-failure-in-the-emergency-department-the-safe-simeu-epidemiological-study
#8
Andrea Fabbri, Giulio Marchesini, Giorgio Carbone, Roberto Cosentini, Annamaria Ferrari, Mauro Chiesa, Alessio Bertini, Federico Rea
BACKGROUND: Patients with acute heart failure (AHF) have high rates of attendance to emergency departments (EDs), with significant health care costs. OBJECTIVES: We aimed to describe the clinical characteristics of patients attending Italian EDs for AHF and their diagnostic and therapeutic work-up. METHODS: We carried out a retrospective analysis on 2683 cases observed in six Italian EDs for AHF (January 2011 to June 2012). RESULTS: The median age of patients was 84 years (interquartile range 12), with females accounting for 55...
May 10, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28497538/multimodality-imaging-of-a-left-ventricular-aneurysm-in-a-patient-with-normal-coronary-arteries-unusual-localization
#9
Mahmut Yesin, Macit Kalçık, Elnur Alizade, Onur Taşar, Mehmet Özkan
Left ventricular aneurysm (LVA) is rare but potentially fatal complication of myocardial infarction. It has been strictly defined as a distinct area of abnormal left ventricular diastolic contour with systolic dyskinesia or paradoxical bulging. It may be asymptomatic. However, complications including thromboembolism, heart failure, valvular regurgitation, arrhythmia, and rarely rupture may be the initial presentation. Diagnosis may be established by transthoracic echocardiography, left ventriculography, computed tomographic angiography, and cardiac magnetic resonance imaging...
May 12, 2017: Echocardiography
https://www.readbyqxmd.com/read/28491484/valvular-hemolysis-masquerading-as-prosthetic-valve-stenosis
#10
Pooja Sethi, Ghulam Murtaza, Zia Rahman, Syed Zaidi, Thomas Helton, Timir Paul
The evaluation of prosthetic valves can provide a unique challenge, and a thoughtful approach is required. High output states like anemia should be kept in the differential when evaluating elevated gradients across prosthetic valves. We present the case of a 69-year-old man with a Starr-Edwards prosthetic aortic valve who presented with symptoms of congestive heart failure and high transvalvular pressure gradients. These symptoms indicate a potential prosthetic valve stenosis. His laboratory evaluation results were consistent with valve-related hemolysis...
April 8, 2017: Curēus
https://www.readbyqxmd.com/read/28486870/long-term-cardiac-morbidity-and-mortality-in-patients-with-aortic-valve-disease-following-liver-transplantation-a-case-matching-study
#11
Ramona Nicolau-Raducu, Thomas Marshall, Hamang Patel, Kelly Ural, Joseph Koveleskie, Susan Smith, Donald Ganier, Bryan Evans, Brian Fish, William Daly, Ari J Cohen, George Loss, Amjad Bokhari, Bobby Nossaman
INTRODUCTION: This retrospective study examined the role of aortic valve (AV) disease in patients who underwent orthotopic liver transplantation (OLT) to determine the incidence of postoperative cardiac morbidity and mortality when compared with a matched control group without AV disease. METHODS: Patients were included in the AV group if diagnosed with aortic stenosis (AS) or aortic regurgitation or had received AV replacement prior to OLT. The AV group (n = 53) was matched to a control group (n = 212) with the following preoperative variables: type of organ transplanted, age, gender, race, body mass index, MELD, redo-transplantation, preoperative renal replacement therapy, nonalcoholic steatohepatitis, viral hepatitis, diabetes, and coronary artery disease...
May 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28483032/advances-in-diagnosis-and-management-of-mitochondrial-cardiomyopathy
#12
Ruiqi Zhuge, Rong Zhou, Xinhai Ni
Mitochondrial cardiomyopathy (MCM) is a series of myocardial conditions characterized by abnormal heart-muscle structure,function,or both,secondary to genetic defects involving the mitochondrial respiratory chain,in the absence of concomitant coronary artery disease,hypertension,valvular disease,or congenital heart disease. MCM patients typically have hypertrophic or dilated cardiomyopathy. Arrhythmias and left ventricular myocardial noncompaction are less common,and heart failure may occur as the first symptom in some patients...
April 20, 2017: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
https://www.readbyqxmd.com/read/28481153/von-willebrand-factor-as-a-novel-player-in-valvular-heart-disease-from-bench-to-valve-replacement
#13
Felice Gragnano, Mario Crisci, Maurizio Cappelli Bigazzi, Renatomaria Bianchi, Simona Sperlongano, Francesco Natale, Fabio Fimiani, Claudia Concilio, Arturo Cesaro, Ivana Pariggiano, Vincenzo Diana, Giuseppe Limongelli, Plinio Cirillo, Mariagiovanna Russo, Enrica Golia, Paolo Calabrò
von Willebrand Factor (vWF) is a well-known mediator of hemostasis and vascular inflammation. Its dynamic modulation in the bloodstream, according to hemodynamic conditions, makes it an appealing biomarker in patients with valvular heart disease (VHD). Recent studies highlight the close connection between vWF and VHD, with possible implications in the pathogenesis of VHD, promoting valve aging and calcification or favoring the development of infective endocarditis. Moreover, vWF has been recently proposed as a new diagnostic and prognostic tool in patients with valve stenosis or regurgitation, showing a strict correlation with severity of valve disease, outcome, and bleeding (Heyde syndrome)...
January 1, 2017: Angiology
https://www.readbyqxmd.com/read/28476875/traditional-cardiovascular-risk-factors-and-their-relation-to-future-surgery-for-valvular-heart-disease-or-ascending-aortic-disease-a%C3%A2-case-referent-study
#14
Johan Ljungberg, Bengt Johansson, Karl Gunnar Engström, Elin Albertsson, Paul Holmer, Margareta Norberg, Ingvar A Bergdahl, Stefan Söderberg
BACKGROUND: Risk factors for developing heart valve and ascending aortic disease are based mainly on retrospective data. To elucidate these factors in a prospective manner, we have performed a nested case-referent study using data from large, population-based surveys. METHODS AND RESULTS: A total of 777 patients operated for heart valve disease or disease of the ascending aorta had previously participated in population-based health surveys in Northern Sweden. Median time (interquartile range) from survey to surgery was 10...
May 5, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28473138/antiphospholipid-syndrome-role-of-vascular-endothelial-cells-and-implications-for-risk%C3%A2-stratification-and-targeted-therapeutics
#15
REVIEW
Michel T Corban, Ali Duarte-Garcia, Robert D McBane, Eric L Matteson, Lilach O Lerman, Amir Lerman
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by venous thromboembolism, arterial thrombosis, and obstetric morbidities in the setting of persistently positive levels of antiphospholipid antibodies measured on 2 different occasions 12 weeks apart. Patients with APS are at increased risk for accelerated atherosclerosis, myocardial infarction, stroke, and valvular heart disease. Vascular endothelial cell dysfunction mediated by antiphospholipid antibodies and subsequent complement system activation play a cardinal role in APS pathogenesis...
May 9, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28473068/acr-appropriateness-criteria-%C3%A2-dyspnea-suspected-cardiac-origin
#16
Jens Vogel-Claussen, Amany S M Elshafee, Jacobo Kirsch, Richard K J Brown, Lynne M Hurwitz, Cylen Javidan-Nejad, Paul R Julsrud, Christopher M Kramer, Rajesh Krishnamurthy, Archana T Laroia, Jonathon A Leipsic, Kalpesh K Panchal, Amar B Shah, Richard D White, Pamela K Woodard, Suhny Abbara
This article discusses imaging guidelines for five dyspnea variants: (1) dyspnea due to heart failure, ischemia not excluded; (2) dyspnea due to suspected nonischemic heart failure, ischemia excluded; (3) dyspnea due to suspected valvular heart disease, ischemia excluded; (4) dyspnea due to suspected cardiac arrhythmia, ischemia excluded; and (5) dyspnea due to suspected pericardial disease, ischemia excluded. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28464518/6q25-1-tab2-microdeletion-syndrome-congenital-heart-defects-and-cardiomyopathy
#17
Andrew Cheng, Mary Beth P Dinulos, Whitney Neufeld-Kaiser, Jill Rosenfeld, McKenna Kyriss, Suneeta Madan-Khetarpal, Hiba Risheg, Peter H Byers, Yajuan J Liu
Congenital heart defects (CHD) are the most frequent type of congenital anomaly and are often associated with genetic and chromosomal syndromes. Haploinsufficiency of TAB2 (TGF-beta activated kinase 1/MAP3K7 binding protein 2) has been proposed to cause valvular and cardiac outflow tract structural abnormalities. In this study, we describe 13 newly identified individuals with microdeletions of chromosome 6q25.1 that involve TAB2. One of the patients in our study cohort has the smallest deletion yet reported, affecting only TAB2...
May 2, 2017: American Journal of Medical Genetics. Part A
https://www.readbyqxmd.com/read/28462757/can-whole-blood-parameters-be-used-in-follow-up-of-children-with-rheumatic-valvular-heart-disease
#18
Derya Karpuz, Dilek Giray, Abdullah Ozyurt, Gulcin Bozlu, Selma Unal, Olgu Hallioglu
OBJECTIVES: The aim of the present study was to investigate the relationships between red blood cell distribution width, platelet distribution width, and mean platelet volume and the presence and severity of valvular involvement in patients with rheumatic heart disease. METHODS: Between April, 2012 and December, 2015, 151 patients who were admitted to the Pediatric Cardiology Unit with diagnosis of rheumatic heart disease and 148 healthy children were included to our study...
May 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28460874/risk-index-for-postoperative-acute-kidney-injury-after-valvular-surgery-using-cardiopulmonary-bypass
#19
Takashi Yamauchi, Shigeru Miyagawa, Yasushi Yoshikawa, Koichi Toda, Yoshiki Sawa
BACKGROUND: Acute kidney injury (AKI) after valvular surgical procedures with cardiopulmonary bypass carries potentially high mortality and morbidity rates. This study investigated the risk factors for AKI, and the study investigators developed a risk index to predict postoperative AKI. METHODS: A total of 1,484 consecutive non-dialysis-dependent patients who underwent valvular operations using cardiopulmonary bypass between 2008 and 2011 were retrospectively investigated...
April 28, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28460759/utility-of-physical-examination-and-comparison-to-echocardiography-for-cardiac-diagnosis
#20
Ashish Patel, Nitin Singh Tomar, Anil Bharani
OBJECTIVE: To find out the accuracy of cardiac auscultation using non-digital stethoscope in physical diagnosis of cardiac diseases. METHODS: We enrolled 104 consecutive patients with abnormal cardiac auscultatory findings attending cardiology clinic and not previously evaluated by echocardiography. One time detailed cardiac physical examination followed by echocardiography within 1 month was undertaken. Agreement between two methods was calculated using mean pair percentage agreement, kappa statistics (κ) and calculation of 95% confidence interval (CI) for kappa statistics...
March 2017: Indian Heart Journal
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