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https://www.readbyqxmd.com/read/29035428/initial-report-of-the-korean-organ-transplant-registry-kotry-heart-transplantation
#1
Hae Young Lee, Eun Seok Jeon, Seok Min Kang, Jae Joong Kim
BACKGROUND AND OBJECTIVES: The Korean Organ Transplant Registry (KOTRY), which was the first national transplant registry in Korea, was founded by the Korean Society for Transplantation and the Korean Center for Disease Control in 2014. Here, we present the initial report of the Korean Heart Transplant Registry. METHODS: A total of 183 heart transplantation (HTPL) patients performed at 4 nationally representative hospitals were collected from April 2014 to December 2015...
August 16, 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/29033310/relation-of-elevated-serum-uric-acid-levels-to-first-degree-heart-block-and-other-cardiac-conduction-defects-in-hospitalized-patients-with-type-2-diabetes
#2
Alessandro Mantovani, Riccardo Rigolon, Isabella Pichiri, Giovanni Morani, Stefano Bonapace, Clementina Dugo, Giacomo Zoppini, Enzo Bonora, Giovanni Targher
AIMS: Several studies have reported that moderately elevated serum uric acid levels are associated with an increased risk of tachyarrhythmias (mainly atrial fibrillation) in patients with and without type 2 diabetes mellitus (T2DM). It is currently unknown whether an association also exists between elevated serum uric acid levels and cardiac conduction defects in patients with T2DM. METHODS: We retrospectively analyzed a hospital-based sample of 967 patients with T2DM discharged from our Division of Endocrinology over the years 2007-2014...
September 20, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29031049/heart-valve-scaffold-fabrication-bioinspired-control-of-macro-scale-morphology-mechanics-and-micro-structure
#3
Antonio D'Amore, Samuel K Luketich, Giuseppe M Raffa, Salim Olia, Giorgio Menallo, Antonino Mazzola, Flavio D'Accardi, Tamir Grunberg, Xinzhu Gu, Michele Pilato, Marina V Kameneva, Vinay Badhwar, William R Wagner
Valvular heart disease is currently treated with mechanical valves, which benefit from longevity, but are burdened by chronic anticoagulation therapy, or with bioprosthetic valves, which have reduced thromboembolic risk, but limited durability. Tissue engineered heart valves have been proposed to resolve these issues by implanting a scaffold that is replaced by endogenous growth, leaving autologous, functional leaflets that would putatively eliminate the need for anticoagulation and avoid calcification. Despite the diversity in fabrication strategies and encouraging results in large animal models, control over engineered valve structure-function remains at best partial...
October 6, 2017: Biomaterials
https://www.readbyqxmd.com/read/29029000/spindle-cell-sarcoma-of-the-mitral-valve-a-rare-indication-for-mitral-valve-replacement
#4
John Nicholas Roche Massey, S Kim Suvarna, Karol Krawczyk, Steven Hunter
Primary cardiac tumours are a rare finding and even rarer cause of valvular heart disease. We report a case of cardiac spindle cell sarcoma mimicking mitral valve stenosis and the subsequent operative management.
September 26, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29027633/multi-modality-imaging-in-the-evaluation-and-treatment-of-mitral-regurgitation
#5
REVIEW
Marc-André Bouchard, Claudia Côté-Laroche, Jonathan Beaudoin
Mitral regurgitation (MR) is frequent and associated with increased mortality and morbidity when severe. It may be caused by intrinsic valvular disease (primary MR) or ventricular deformation (secondary MR). Imaging has a critical role to document the severity, mechanism, and impact of MR on heart function as selected patients with MR may benefit from surgery whereas other will not. In patients planned for a surgical intervention, imaging is also important to select candidates for mitral valve (MV) repair over replacement and to predict surgical success...
October 13, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29025406/impact-of-empagliflozin-on-subclinical-left-ventricular-dysfunctions-and-on-the-mechanisms-involved-in-myocardial-disease-progression-in-type-2-diabetes-rationale-and-design-of-the-empa-heart-trial
#6
Andrea Natali, Lorenzo Nesti, Iacopo Fabiani, Enrico Calogero, Vitantonio Di Bello
BACKGROUND: Asymptomatic left ventricular (LV) dysfunction is highly prevalent in type 2 diabetes patients. Unlike the other hypoglycemic drugs, SGLT2 inhibitors have shown potential benefits for reducing cardiovascular death and risk factors, aside from lowering plasma glucose levels. With this study we aim at determining whether the treatment with empagliflozin is associated with an improvement in LV functions in diabetic patients with asymptomatic LV dysfunction against Sitagliptin, which is presumably neutral on myocardial function...
October 12, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29022745/real-world-adherence-to-oral-anticoagulant-in-non-valvular-atrial-fibrillation-patients-in-china
#7
Xiao Xiang, Yaying Cao, Kexin Sun, Jing Song, Yaohua Tian, Qiongzhou Yin, Juan Juan, Yonghua Hu
BACKGROUND AND OBJECTIVE: Adherence to oral anticoagulants is crucial for the prevention of ischemic stroke in atrial fibrillation patients; however, evidence of oral-anticoagulant adherence from developing countries is still lacking. Our study aimed to evaluate the current situation and predictors of oral-anticoagulant adherence in non-valvular atrial fibrillation (NVAF) patients in China. METHODS: Records of NVAF patients were obtained from a regional claims database...
October 12, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29021274/prevalence-and-outcomes-of-left-sided-valvular-heart-disease-associated-with-chronic-kidney-disease
#8
Zainab Samad, Joseph A Sivak, Matthew Phelan, Phillip J Schulte, Uptal Patel, Eric J Velazquez
BACKGROUND: Chronic kidney disease (CKD) is an adverse prognostic marker for valve intervention patients; however, the prevalence and related outcomes of valvular heart disease in CKD patients is unknown. METHODS AND RESULTS: Included patients underwent echocardiography (1999-2013), had serum creatinine values within 6 months before index echocardiogram, and had no history of valve surgery. CKD was defined as diagnosis based on the International Classification of Diseases, Ninth Revision or an estimated glomerular filtration rate <60 mL/min per 1...
October 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29016910/left-atrial-appendage-occluder-implantation-in-europe-indications-and-anticoagulation-post-implantation-results-of-the-european-heart-rhythm-association-survey
#9
Roland Richard Tilz, Tatjana Potpara, Jian Chen, Dan Dobreanu, Torben Bjerregaard Larsen, Kristina Herman Haugaa, Nikolaos Dagres
The aim of this EP Wire survey was to assess the indications and anticoagulation strategies post-left atrial appendage occluder (LAAO) implantation for stroke prevention in patients with non-valvular atrial fibrillation in Europe. A total of 33 centres in 13 European countries completed the survey. All centres were members of the European Heart Rhythm Association Electrophysiology Research Network. Left atrial appendage occluder procedures were performed by electrophysiologists in 52% of the centres and by interventional cardiologists in the remaining centres...
September 18, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29016832/contemporary-stroke-prevention-strategies-in-11%C3%A2-096-european-patients-with-atrial-fibrillation-a-report-from-the-eurobservational-research-programme-on-atrial-fibrillation-eorp-af-long-term-general-registry
#10
Giuseppe Boriani, Marco Proietti, Cécile Laroche, Laurent Fauchier, Francisco Marin, Michael Nabauer, Tatjana Potpara, Gheorghe-Andrei Dan, Zbigniew Kalarus, Igor Diemberger, Luigi Tavazzi, Aldo P Maggioni, Gregory Y H Lip
Aims: Contemporary data regarding atrial fibrillation (AF) management and current use of oral anticoagulants (OACs) for stroke prevention are needed. Methods and results: The EURObservational Research Programme on AF (EORP-AF) Long-Term General Registry analysed consecutive AF patients presenting to cardiologists in 250 centres from 27 European countries. From 2013 to 2016, 11 096 patients were enrolled (40.7% female; mean age 69 ± 11 years). At discharge, OACs were used in 9379 patients (84...
September 14, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28994867/mid-terme-results-of-cardiac-surgery-of-valve-replacement-by-mechanical-prosthesis-about-861-patients
#11
Djafer Boulanouar
BACKGROUND: Patients with mechanical valvular prostheses are becoming more numerous in our country. Their medical care poses a number of problems in a particular socio-economic context of our geographical regions. AIM: The purpose of this study was to identify the complications of this heart valve replacement surgery by mechanical prostheses and try to compare our results with those of literature. METHODS: From January 1998 to June 2003, 861 patients were operated for acquired valvular heart disease (413 men and 448 women), average age 39±11 years...
November 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28994679/ischemic-mitral-regurgitation
#12
REVIEW
Praveen Kerala Varma, Neethu Krishna, Reshmi Liza Jose, Ashish Narayan Madkaiker
Ischemic mitral regurgitation (IMR) is a frequent complication of left ventricular (LV) global or regional pathological remodeling due to chronic coronary artery disease. It is not a valve disease but represents the valvular consequences of increased tethering forces and reduced closing forces. IMR is defined as mitral regurgitation caused by chronic changes of LV structure and function due to ischemic heart disease and it worsens the prognosis. In this review, we discuss on etiology, pathophysiology, and mechanisms of IMR, its classification, evaluation, and therapeutic corrective methods of IMR...
October 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28990938/-the-new-changes-in-the-european-society-of-cardiology-2017-guidelines-for-the-management-of-valvular-heart-disease
#13
EDITORIAL
Recep Demirbağ
No abstract text is available yet for this article.
October 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28990646/-clinical-profile-and-satisfaction-with-anticoagulated-treatment-in-patients-with-non-valvular-atrial-fibrillation-attended-in-internal-medicine-and-neurology-departments-of-spain
#14
(no author information available yet)
AIM: To determine the clinical profile, management of anticoagulant treatment and satisfaction related to anticoagulation in outpatients with nonvalvular atrial fibrillation attended in Neurology or Internal Medicine departments of Spain. PATIENTS AND METHODS: Cross-sectional and multicenter study, in which 1,337 outpatients were included. Patients fulfilled ACTS, SAT-Q and EQ-5D questionnaires. RESULTS: 865 patients (64.7%) were recruited from Neurology department and 472 (35...
October 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28990316/non-invasive-assessment-of-left-ventricular-filling-pressure
#15
REVIEW
Sherif F Nagueh
Dyspnoea is a presenting symptom for patients with heart failure. It is often due to elevated left ventricular (LV) filling pressure but can be due to pulmonary disease or other non-cardiac reasons. While physical examination is useful, it has its limitations. Accordingly, non-invasive imaging has an important role in the diagnostic evaluation of patients with known or suspected heart failure. Echocardiography is usually the first test obtained and is used to determine LV volumes, ejection fraction and mass as well as right ventricular size and function, left and right atrial volumes, valvular lesions, and pulmonary artery pressures...
October 8, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28988424/maintenance-of-valvular-integrity-with-impella-left-heart-support-results-from-the-multicenter-protect-ii-randomized-study
#16
James A Goldstein, Simon R Dixon, Pamela S Douglas, E Magnus Ohman, Jeffrey Moses, Jeffrey J Popma, William W O'Neill
BACKGROUND: The Impella 2.5 axial flow pump, which is positioned across the aortic valve, is widely employed for hemodynamic support. The present study compared structural and functional integrity of the left heart valves in patients undergoing Impella vs intra-aortic balloon pump in the randomized PROTECT II trial. METHODS AND RESULTS: Transthoracic echocardiograms were performed at baseline, 1 and 3 months in 445 patients in the PROTECT II trial. Serial studies were analyzed by an independent echocardiography core laboratory for aortic and mitral valve structure and function, and left ventricular ejection fraction (LVEF)...
October 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28986061/adverse-cardiovascular-outcomes-in-atrial-fibrillation-validation-of-the-new-2mace-risk-score
#17
Marija Polovina, Dijana Đikić, Ana Vlajković, Matej Vilotijević, Ivan Milinković, Milika Ašanin, Miodrag Ostojić, Andrew J S Coats, Petar M Seferović
BACKGROUND: In addition to thromboembolism, atrial fibrillation (AF) may also predispose to major adverse cardiovascular events (MACE) attributable to coronary artery disease (CAD), including myocardial infarction (MI). The 2MACE score (2 points - Metabolic syndrome and Age≥75years, 1 point - MI/revascularization, Congestive heart failure/ejection-fraction <40%, and thrombo-Embolism) was recently proposed to help identify AF patients at risk of MACE. We assessed the predictive validity of the 2MACE score for MACE occurrence in AF patients free of CAD at baseline...
September 18, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28984893/the-years-2015-2016-in-the-european-heart-journal-cardiovascular-imaging-part-i
#18
Thor Edvardsen, Erwan Donal, Chiara Bucciarelli-Ducci, Pál Maurovich-Horvat, Gerald Maurer, Bogdan A Popescu
The multimodality cardiovascular imaging journal, European Heart Journal-Cardiovascular Imaging, was launched in 2012. It has gained an impressive impact factor of 5.99 during its 5 first years and is now established as the most important cardiovascular imaging journal in Europe. The most important studies from the journal's forth and fifth years will be highlighted in two reports. Part I of the review will focus on studies about myocardial function and risk prediction, myocardial ischaemia, and emerging techniques in cardiovascular imaging, while Part II will focus on valvular heart disease, heart failure, cardiomyopathies, and congenital heart disease...
October 1, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28983742/multi-resolution-geometric-modeling-of-the-mitral-heart-valve-leaflets
#19
Amir H Khalighi, Andrew Drach, Robert C Gorman, Joseph H Gorman, Michael S Sacks
An essential element of cardiac function, the mitral valve (MV) ensures proper directional blood flow between the left heart chambers. Over the past two decades, computational simulations have made marked advancements toward providing powerful predictive tools to better understand valvular function and improve treatments for MV disease. However, challenges remain in the development of robust means for the quantification and representation of MV leaflet geometry. In this study, we present a novel modeling pipeline to quantitatively characterize and represent MV leaflet surface geometry...
October 5, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28978603/percutaneous-balloon-pulmonary-valvuloplasty-pbpv-of-extreme-pulmonary-valve-stenosis-by-the-use-of-accura-balloon
#20
Santosh Kumar Sinha, Vikas Mishra, Mahmadula Razi, Mukesh Jitendra Jha
Transcatheter therapy of valvular pulmonary stenosis is one of first catheter interventions facilitating its application in field of structural heart disease and now treatment of choice for significant pulmonary stenosis. Myriads of balloon catheter have been used for this purpose starting from Diamond (Boston Scientific,Natick, MA USA), Marshal (Medi-Tech,Watertown MAUSA), Innoue balloon, Tyshak I and currently Tyshak II. Diameter and length of balloon depend on size of annulus and age group, respectively...
October 4, 2017: BMJ Case Reports
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