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"psychogenic non epileptic seizures"

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https://www.readbyqxmd.com/read/29588989/psychogenic-non-epileptic-seizures-among-patients-with-functional-neurological-disorder-a-case-series-from-a-tanzanian-referral-hospital-and-literature-review
#1
Marieke C J Dekker, Sarah J Urasa, Marissa Kellogg, William P Howlett
Objective: Functional neurological disorders (FNDs) and psychogenic nonepileptic seizures (PNES) are likely as common in Sub-Saharan Africa (SSA) as in the rest of the world, but there is a dearth of literature on the epidemiology and clinical presentation of these disorders in Africa. The purpose of this paper is to describe a case series of FNDs presenting to a referral hospital in SSA. In addition, we review the existing literature on FNDs in Africa. Methods: A hospital-based retrospective cross-sectional study was conducted to determine the prevalence, epidemiology, and clinical phenotype of FNDs and PNES in a referral hospital in Northern Tanzania over a 6-year period (2007-2013)...
March 2018: Epilepsia Open
https://www.readbyqxmd.com/read/29573595/post-traumatic-stress-and-relationships-to-coping-and-alexithymia-in-patients-with-psychogenic-non-epileptic-seizures
#2
Ruifan Zeng, Lorna Myers, Marcelo Lancman
PURPOSE: There is increasing evidence that patients with PNES can form subgroups distinguished by emotion dysregulation and comorbid psychological symptoms. The purpose of this study was to determine if patients with comorbid PTSD differ from other patients with PNES in terms of alexithymia and stress coping strategies. METHODS: 156 adult patients with video-EEG confirmed PNES were assessed with the Trauma Symptom Inventory-2 (TSI-2) and diagnostic clinical interview, Toronto Alexithymia Scale (TAS-20), and the Coping Inventory for Stressful Situations (CISS)...
March 10, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29414382/interictal-dysphoric-disorder-further-doubts-about-its-epilepsy-specificity-and-its-independency-from-common-psychiatric-disorders
#3
Kirsten Labudda, Dominik Illies, Christian G Bien, Frank Neuner
PURPOSE: The interictal dysphoric disorder (IDD) is a proposed epilepsy-specific psychiatric condition characterized by a conglomerate of symptoms such as depression, irritability, euphoria, and anxiety. However, there are doubts about IDD as an independent entity and about its presumed epilepsy-specific nature. METHODS: Here, we investigated the association between psychiatric disorders and IDD in 120 patients with epilepsy, also analyzing potential associations between IDD symptoms and epilepsy-related variables...
January 29, 2018: Epilepsy Research
https://www.readbyqxmd.com/read/29414136/optimising-the-use-of-eeg-in-non-epileptic-attack-disorder-results-of-a-uk-national-service-evaluation
#4
Rosalind Kandler, Sarah Lawrence, Catherine Pang, Ming Lai, Kimberley Whitehead
PURPOSE: To produce an evidence base to formulate guidelines for optimal performance of EEG in patients referred with a possible diagnosis of non-epileptic attack disorder (NEAD). METHODS: 51 UK EEG departments participated in the prospective study. A pro-forma was completed for all consecutive patients aged 5 years and over referred for EEG over a six month period. Information obtained included referral diagnosis, occurrence/type of attack during EEG, the use of suggestion, length of recording and who was present during the EEG...
January 10, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29359374/value-of-clinical-features-to-differentiate-refractory-epilepsy-from-mimics-a-prospective-longitudinal-cohort-study
#5
A Labate, L Mumoli, A Curcio, G Tripepi, G D'Arrigo, E Ferlazzo, U Aguglia, C Indolfi, A Quattrone, A Gambardella
BACKGROUND AND PURPOSE: Misdiagnosis of refractory epilepsy (rE) is common and such patients experience a long diagnostic delay. Our aim was to identify key clinical/laboratory factors in order to obtain an alternative diagnosis in patients referred for rE. METHODS: Between January 2010 and December 2015, 125 consecutive patients with a diagnosis of rE were prospectively enrolled. All patients underwent a comprehensive neurological, neuropsychiatric and cardiological evaluation, and had an observation time of at least 1 year after the study entry...
May 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29307332/an-overview-of-psychogenic-non-epileptic-seizures-etiology-diagnosis-and-management
#6
Ángela Milán-Tomás, Michelle Persyko, Martin Del Campo, Colin M Shapiro, Karl Farcnik
The purpose of this review is to provide an update of the research regarding the etiology, diagnosis and management of psychogenic non-epileptic seizures (PNES). A literature search using Pubmed, Ovid MEDLINE and EMBASE database was performed from 2000 up to August 2017. We have evaluated the different factors leading to PNES as well as the diagnostic approach and management of this disorder which continue to be very difficult. The coexistence of epilepsy and PNES poses special challenges and requires the coordinated efforts of the family physicians, psychiatrists, psychologists and neurologists...
March 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29282343/-diagnosis-of-psychogenic-non-epileptic-seizure-how-can-we-detect-it-prior-to-video-electroencephalography-monitoring
#7
Kousuke Kanemoto
It is highly recommended not to base the diagnosis of psychogenic non-epileptic seizures (PNES) on one single sign. Yet, the combination of several symptoms may be highly indicative of PNES. The aim of this paper is to demonstrate that some combinations of symptoms are more easily recorded and that some are more indicative of PNES. We review and analize various symptom combinations including convulsions, falling, and impaired consciousness. Further, we examine and discuss all individual symptoms that are known to be associated with PNES...
December 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29282342/-motor-symptoms-of-autoimmune-encephalopathies
#8
Yuichi Tashiro, Hiroshi Takashima
Autoimmune encephalopathies are clinically and immunologically heterogeneous disorders. At least 20 types of autoimmune encephalopathies have been discovered, with the most common type being Hashimoto encephalopathy. In clinical situations, we often observe that patients with autoimmune encephalopathy are misdiagnosed because they exhibit signs similar to those observed in functional psychogenic movement, conversion, or somatoform disorders. We clinically examined over 100 patients with autoimmune encephalopathy...
December 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/29220065/clinical-profile-of-patients-with-psychogenic-non-epileptic-seizures-in-puerto-rico
#9
Joashlie M Méndez-Ruiz, Alfonso Martínez-Taboas, Yeira M Valdez-Pimentel, Miguel Torres-Narváez, Marianette Colón-Laboy, Gisela G Jiménez-Colón, José Rodríguez-Gómez, Christian J González-Jiménez
OBJECTIVE: Specialized epilepsy clinics receive many cases (20%-30% of total cases) in which the patients are diagnosed with psychogenic non-epileptic seizures (PNES). In Puerto Rico, there has been a lack of research on and data about patients with PNES. This study examined the clinical profile of 34 patients with a confirmed diagnosis of PNES. METHODS: A secondary analysis of 34 clinical records of patients with PNES was conducted. The resulting profile was based on clinical interviews, the behavioral presentation of seizures, the history of traumatic experiences or abuse, and the relationship between PNES events and life stressors...
December 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29175723/brain-tumors-associated-with-psychogenic-non-epileptic-seizures-case-series
#10
Catherine R Garcia, Gulam Q Khan, Amy M Morrow, Priyanka Yadav, Donita D Lightner, Frank G Gilliam, John L Villano
OBJECTIVE: The association of psychogenic non-epileptic seizures (PNES) with primary or secondary brain tumors has not been well described in the literature. We aim to discuss their association, and their impact in brain tumor treatment. PATIENTS AND METHODS: We identified four patients retrospectively from our practice. The diagnosis of PNES was based on clinical suspicion and standard EEG, supplemented with video-EEG recording in 2 patients. RESULTS: The initial diagnosis of brain tumor was associated with a new onset seizure prior to diagnosis...
January 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29132064/patients-and-caregivers-contributions-for-differentiating-epileptic-from-psychogenic-nonepileptic-seizures-value-and-limitations-of-self-reporting-questionnaires-a-pilot-study
#11
Giuseppe Erba, Elisa Bianchi, Giorgia Giussani, John Langfitt, Adam Juersivich, Ettore Beghi
PURPOSE: Questionnaires investigating semiology and comorbidities of psychogenic non-epileptic seizures (PNES) have been used mainly to help physicians expedite referrals to epilepsy centres for confirmation of diagnosis rather than as alternative diagnostic tool when video-EEG monitoring (VEM), the current gold standard, is not available or is inconclusive. METHODS: We developed one structured questionnaire for patients, exploring subjective experiences and vulnerabilities and one for eyewitnesses, focused on features observable during typical events to study prospectively 50 consecutive adult patients with PNES or epileptic seizures (ES) admitted for VEM...
December 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29034101/lamotrigine-induced-sexual-dysfunction-and-non-adherence-case-analysis-with-literature-review
#12
Kenneth R Kaufman, Melissa Coluccio, Kartik Sivaraaman, Miriam Campeas
BACKGROUND: Optimal anti-epileptic drug (AED) treatment maximises therapeutic response and minimises adverse effects (AEs). Key to therapeutic AED treatment is adherence. Non-adherence is often related to severity of AEs. Frequently, patients do not spontaneously report, and clinicians do not specifically query, critical AEs that lead to non-adherence, including sexual dysfunction. Sexual dysfunction prevalence in patients with epilepsy ranges from 40 to 70%, often related to AEDs, epilepsy or mood states...
September 2017: BJPsych Open
https://www.readbyqxmd.com/read/28971651/-utility-of-inpatient-long-term-video-eeg-monitoring
#13
Moshe Herskovitz, Yitzhak Schiller
INTRODUCTION: Ambulatory interictal EEG cannot always clarify the nature of spells in patients with suspected epilepsy. Long term Video EEG Monitoring can help to diagnose the nature of recurrent attacks, classify epileptic seizures and aid with the localization of seizures in preoperative epilepsy surgery candidates. OBJECTIVES: The aim of this study was to investigate the usefulness of performing long term video EEG monitoring in patients undergoing this test in Rambam's epilepsy unit...
September 2017: Harefuah
https://www.readbyqxmd.com/read/28956479/psychogenic-non-epileptic-seizures-in-children-and-adolescents-part-ii-explanations-to-families-treatment-and-group-outcomes
#14
Kasia Kozlowska, Catherine Chudleigh, Catherine Cruz, Melissa Lim, Georgia McClure, Blanche Savage, Ubaid Shah, Averil Cook, Stephen Scher, Pascal Carrive, Deepak Gill
Psychogenic non-epileptic seizures (PNES) - time-limited disturbances of consciousness and motor-sensory control, not accompanied by ictal activity on electroencephalogram (EEG) - are best conceptualized as atypical neurophysiological responses to emotional distress, physiological stressors and danger. Patients and families find the diagnosis of PNES difficult to understand; the transition from neurology (where the diagnosis is made) to mental health services (to which patients are referred for treatment) can be a bumpy one...
January 2018: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28956448/psychogenic-non-epileptic-seizures-in-children-and-adolescents-part-i-diagnostic-formulations
#15
Kasia Kozlowska, Catherine Chudleigh, Catherine Cruz, Melissa Lim, Georgia McClure, Blanche Savage, Ubaid Shah, Averil Cook, Stephen Scher, Pascal Carrive, Deepak Gill
Psychogenic non-epileptic seizures (PNES) are a nonspecific, umbrella category that is used to collect together a range of atypical neurophysiological responses to emotional distress, physiological stressors and danger. Because PNES mimic epileptic seizures, children and adolescents with PNES usually present to neurologists or to epilepsy monitoring units. After a comprehensive neurological evaluation and a diagnosis of PNES, the patient is referred to mental health services for treatment. This study documents the diagnostic formulations - the clinical formulations about the probable neurophysiological mechanisms - that were constructed for 60 consecutive children and adolescents with PNES who were referred to our Mind-Body Rehabilitation Programme for treatment...
January 2018: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28927333/vulnerability-to-psychogenic-non-epileptic-seizures-is-linked-to-low-neuropeptide-y-levels
#16
Michael Winterdahl, Alessandro Miani, Moana J H Vercoe, Antonia Ciovica, Lori Uber-Zak, Charlotte Ulrikka Rask, Paul J Zak
Psychogenic non-epileptic seizures (PNES) is a conversion disorder that reflects underlying psychological distress. Female patients with PNES often present with a history of prolonged stressors, especially sexual abuse. In the current study, we studied the relationship between neuropeptide Y (NPY) and PNES symptoms in women with a history of sexual abuse. NPY has been associated with resilience to stress and we hypothesized that low levels would increase the extent and severity of PNES symptoms in this patient population...
November 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28926747/ictal-source-imaging-and-electroclinical-correlation-in-self-limited-epilepsy-with-centrotemporal-spikes
#17
Jørgen Alving, Martin Fabricius, Ivana Rosenzweig, Sándor Beniczky
PURPOSE: To elucidate the localization of ictal EEG activity, and correlate it to semiological features in self-limited epilepsy with centrotemporal spikes (formerly called "benign epilepsy with centrotemporal spikes"). METHODS: We have performed ictal electric source imaging, and we analysed electroclinical correlations in three patients with self-limited epilepsy with centrotemporal spikes. RESULTS: The source of the evolving rhythmic ictal activity (9...
November 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28808618/neuroimaging-studies-in-patients-with-psychogenic-non-epileptic-seizures-a-systematic-meta-review
#18
REVIEW
Marco Mcsweeney, Markus Reuber, Liat Levita
Psychogenic Non-epileptic Seizures (PNES) are 'medically unexplained' seizure-like episodes which superficially resemble epileptic seizures but which are not caused by epileptiform discharges in the brain. While many experts see PNES disorder as a multifactorial biopsychosocial condition, little is known about the neurobiological processes which may predispose, precipitate and/or perpetuate PNES symptomology. This systematic meta-review advances our knowledge and understanding of the neurobiological correlates of PNES by providing an up-to-date assessment of neuroimaging studies performed on individuals with PNES...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28770498/psychogenic-non-epileptic-seizures
#19
REVIEW
David K Chen, Esha Sharma, W Curt LaFrance
PURPOSE OF REVIEW: In this review, we elucidate the evaluation process involved in the diagnosis of psychogenic non-epileptic seizures (PNES). Minimum clinical criteria required to attain this diagnosis via a staged approach are delineated. The psychological underpinnings and management of PNES from the neurologists' perspective are also explored. RECENT FINDINGS: Helpful clues can be deduced from history-taking, seizure semiology, ictal/peri-ictal physical exam, and ictal/inter-ictal EEG data...
September 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28706099/cross-sectional-study-of-the-hospital-management-of-adult-patients-with-a-suspected-seizure-epic2
#20
Jon Mark Dickson, Hannah Dudhill, Jane Shewan, Sue Mason, Richard A Grünewald, Markus Reuber
OBJECTIVE: To determine the clinical characteristics, management and outcomes of patients taken to hospital by emergency ambulance after a suspected seizure. DESIGN: Quantitative cross-sectional retrospective study of a consecutive series of patients. SETTING: An acute hospital trust in a large city in England. PARTICIPANTS: In 2012-2013, the regions' ambulance service managed 605 481 emergency incidents, 74 141/605 481 originated from Sheffield (a large city in the region), 2121/74 141 (2...
July 13, 2017: BMJ Open
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